Brain_Discovery
EcoTyper_Project, Data processing
Overview
This Script processes and prepares the I-SPY2 dataset, focusing on: - Cleaning, merging, and structuring genomics and radiomics clinical data. - Identifying common patients between datasets. - Ensuring MRI segmentation consistency for further analysis.
Dataset Summary
- Study Reference: PMID:
35623341
- Clinical Trial: ISPY2/NCT01042379
- Data Source: GEO:
GSE194040
- Study Population:
- Genomics Data: 987 patients (mRNA & RPPA
profiling)
- Radiomics Data: 985 patients (MRI scans)
- Genomics Data: 987 patients (mRNA & RPPA
profiling)
- Platforms Used:
- Genomics: Agilent 44K arrays
- Radiomics: MRI (DCE-MRI)
- Genomics: Agilent 44K arrays
Treatment Details
- Total Patients (RNA-seq): 987
- Total Patients (MRI): 985 (719 I-SPY2 cases, 266
ACRIN-6698 cases)
- Treatment Groups:
- IO + Chemo: 69 patients
- Chemo + Targeted Therapy: 687 patients
- Chemo Alone: 179 patients
- Targeted Therapy Alone: 52 patients
- IO + Chemo: 69 patients
- Key Treatment Arms:
- Paclitaxel ± Trastuzumab
- Veliparib + Carboplatin
- AMG-386 (Trebananib) ± Trastuzumab
- Neratinib, Ganetespib, Ganitumab, Pembrolizumab, Pertuzumab, T-DM1
- Paclitaxel ± Trastuzumab
Treatment Arms
- Chemotherapy ± IO
- Paclitaxel ± Trastuzumab
- Veliparib + Carboplatin
- Paclitaxel ± Trastuzumab
- Targeted Therapies
- AMG-386 (Trebananib) ± Trastuzumab
- Neratinib, Ganetespib, Ganitumab, Pembrolizumab, Pertuzumab, T-DM1
- AMG-386 (Trebananib) ± Trastuzumab
Additional Information
- Batch Correction:
- ComBat was applied to correct batch effects in gene
expression data.
- Adjusted ~800 patients; linear adjustments applied to remaining cases.
- ComBat was applied to correct batch effects in gene
expression data.
- Radiomics Data:
- MRI dataset includes 4 serial DCE-MRI scans per
patient.
- Performed before and during neoadjuvant chemotherapy to track tumor volume changes and response.
- MRI dataset includes 4 serial DCE-MRI scans per
patient.
- Data Availability:
- 📂 Genomics: Available in GEO:
GSE194040.
- 📂 Imaging: MRI datasets accessible via The Cancer Imaging Archive (ISPY2 Collection).
- 📂 Genomics: Available in GEO:
GSE194040.
- Key Reference:
- Wolf DM et al., Cancer Cell, 2022. PMID: 35623341.
Section 1: Data Processing
Load Libraries
Load Genomics Data
Load MultiAssayExperiment .rds File This step
extracts clinical, expression(Microarray quantile
normalizated), and annotation data** for further analysis.
# Define base directory.
input_dir <- file.path(here(), "data/rawdata/genomics")
output_dir <- file.path(here(), "data/results/genomics")
# Load dataset
mae <- readRDS(file.path(input_dir, "ICB_Wolf.rds"))
# Extract clinical, expression, and annotation data
clin <- data.frame(colData(mae))
expr <- assays(mae)[["expr"]] # dim 18348 x 987
annot <- data.frame(rowData(mae@ExperimentList$expr))
# Create a named vector to map gene_id to gene_name
gene_map <- setNames(annot$gene_name, annot$gene_id)
rownames(expr) <- gene_map[rownames(expr)]
rownames(annot) <- annot$gene_nameClinical Data
Display first 50 rows of Clinical Data.
# Display clin
kable(head(clin,50), caption = "Genomics Clinical Data") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| patientid | sex | age | cancer_type | histo | tissueid | stage | response.other.info | recist | response | treatment | dna | rna | survival_time_pfs | event_occurred_pfs | survival_time_os | event_occurred_os | survival_unit | survival_type | TMB_raw | nsTMB_raw | indel_TMB_raw | indel_nsTMB_raw | TMB_perMb | nsTMB_perMb | indel_TMB_perMb | indel_nsTMB_perMb | CIN | CNA_tot | AMP | DEL | treatmentid | dna_info | rna_info | Arm..short.name. | pCR | HR | HER2 | MP2 | Immune. | DRD. | BP.subtype | Receptor.Subtype | I.SPY2.Subtypes | RPS.5 | BP.HER2.2..6 | BP.HER2.2..4 | BP.HER2.2..Immune.5 | BP.HR.HER2.2..Immune.6 | HER2.3.state..3. | BP.HR.HER2.3..6 | BP.HER2.3..6 | BP.Immune.HER2.3..5 | BP.HR.Immune.HER2.3..6 | DRD.Immune.HER2.3..6 | RPS.7..i.e..DRD.Immune.HR.HER2.3..7. | ICS5_score | Chemokine12_score | Module5_TcellBcell_score | STAT1_sig | Module3_IFN_score | Dendritic_cells | B_cells | Mast_cells | Module11_Prolif_score | MP_index_adj…1. | Basal_Index | PARPi7_score | PARPi7_plus_MP2 | VCpred_TN | STMN1_dat | HER2_Index | Mod7_ERBB2 | ERBB2.Y1248 | EGFR.Y1173 | mTOR.S2448 | IGF1R_dat | TIE2.Y992 | Mod10_ECM | RPL24_dat | LYMPHS_PCA_16704732 | Luminal_Index | ER_PGR_avg | PAM50.Subtype | TNBCtype_7class | TNBC_BB_4class | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| X100899 | X100899 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20870 | 0.796000 | 0.63020 | 1.036000 | 0.193300 | -0.08080 | -0.064170 | -0.06758 | -0.38930 | -0.07714 | 1.22300 | 0.99240 | 0.86020 | 0.191100 | -1.06900 | -0.6318 | -0.79760 | NA | NA | NA | -0.7939000 | NA | 0.28970 | -0.24500 | -0.823600 | -0.72510 | -0.497100 | Basal | BL2 | LAR |
| X102011 | X102011 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.21900 | 0.509100 | 0.65020 | 0.299100 | -0.362000 | 0.75260 | 0.426100 | -0.54970 | 1.17800 | 1.37800 | 1.11000 | 0.66820 | 0.93300 | -0.524900 | 0.20960 | -0.5996 | -0.67160 | NA | NA | NA | -0.3970000 | NA | -1.99300 | 3.00200 | 2.261000 | -0.74760 | -0.191700 | Basal | NA | NA |
| X102212 | X102212 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 | NA | NA | MK2206 | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.10000 | 0.978200 | 1.43200 | 0.367300 | 0.253600 | 0.59370 | 2.008000 | 1.25100 | -2.17800 | -1.29500 | 0.90250 | -0.28720 | -0.58080 | 1.100000 | -0.94570 | -0.4772 | -0.74750 | NA | NA | NA | 0.1968000 | NA | 0.98770 | 0.78080 | -0.686600 | 0.01676 | 0.118600 | Normal | MSL | MES |
| X103693 | X103693 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | HR+HER2-/BP_Basal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | -0.83620 | -1.249000 | -1.12600 | -1.293000 | -1.353000 | -0.39820 | -0.444500 | 0.09109 | -0.84910 | -0.21730 | -0.26370 | -0.05050 | -0.10260 | -0.521800 | -0.94400 | -0.5073 | -0.31860 | -0.2776 | -0.26030 | 0.07633 | 0.2533000 | NA | 0.40100 | 0.25040 | -0.293600 | -0.62400 | -0.556700 | Her2 | NA | NA |
| X103939 | X103939 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.87290 | -1.231000 | -1.18500 | -1.959000 | -1.958000 | -0.80620 | -0.649100 | -0.48040 | 1.23000 | -1.00400 | -1.16000 | -0.76310 | -0.93200 | -0.730200 | 0.69100 | -0.6237 | 0.09161 | -0.3335 | -0.28550 | -0.15270 | 0.9003000 | NA | -0.91140 | 0.54750 | 1.307000 | 1.58500 | 2.070000 | LumB | NA | NA |
| X104268 | X104268 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 0 | 0 | 1 | 0 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -1.56300 | -1.605000 | -1.33500 | -1.019000 | 0.868600 | -0.61490 | -1.063000 | -1.00500 | 1.28400 | 0.99390 | 0.98400 | -1.58700 | -1.17000 | -2.076000 | 0.03416 | -0.2965 | -0.27290 | -0.3607 | -0.31670 | 0.27420 | 0.8947000 | NA | -0.61660 | -0.93500 | 0.044230 | -0.54810 | -0.728500 | Basal | UNS | BLIS |
| X104384 | X104384 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.22970 | 0.013520 | -0.25040 | -0.004404 | -1.204000 | 0.10850 | 0.032630 | 0.06288 | -0.07652 | 0.74950 | 1.02600 | 0.45570 | 0.58780 | -0.000986 | -0.23910 | -0.6197 | -1.16600 | -0.3734 | -0.38780 | -1.51100 | -0.5201000 | NA | 0.73450 | -0.66640 | -0.746000 | -0.67450 | -0.801800 | Basal | NA | NA |
| X105286 | X105286 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.33670 | 0.147300 | -0.06257 | -0.698500 | -0.095280 | 0.55290 | -0.486900 | 2.62900 | -1.70900 | -1.83500 | -0.91570 | -0.86400 | -1.22800 | -1.032000 | -1.20400 | -0.5033 | -0.76620 | NA | NA | NA | 0.4573000 | NA | 1.20900 | 0.90320 | 0.114800 | 1.02600 | 0.980500 | LumA | NA | NA |
| X105513 | X105513 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.42990 | -0.086500 | -0.03396 | -0.347600 | -0.973400 | -0.09498 | 0.300300 | -1.61100 | 1.17300 | 0.86810 | 0.02009 | 0.58810 | 0.73500 | 0.501700 | 1.10600 | -0.5595 | -0.03981 | -0.4617 | -0.35570 | -0.38710 | -1.6900000 | 3.0940 | -1.26800 | 0.78080 | -0.490400 | -0.72790 | -1.084000 | Her2 | NA | NA |
| X107700 | X107700 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 + Trastuzumab | NA | NA | MK2206 | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.89600 | -0.263100 | -0.64080 | -0.435200 | -0.206300 | -0.09306 | -0.679500 | 0.75780 | -0.01925 | -1.27700 | -1.04500 | -1.48900 | -1.64600 | -1.074000 | -0.80560 | 1.0560 | -0.12160 | -0.4019 | -0.42400 | -1.15400 | 1.6790000 | 0.4305 | 0.22030 | -1.96700 | 0.115800 | 0.67150 | 0.858000 | LumB | NA | NA |
| X108939 | X108939 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 0 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.83290 | 0.605100 | 0.54100 | -0.004226 | -0.844100 | 0.90340 | 0.281000 | 1.14000 | -0.37790 | -0.41850 | -0.81740 | -0.05181 | -0.15370 | 0.272100 | -0.73640 | 2.2950 | 1.89800 | 2.0010 | 2.44000 | 0.33000 | -0.2396000 | -0.4657 | 0.87950 | 0.67270 | -0.608400 | -0.59870 | -0.101200 | Her2 | NA | NA |
| X108969 | X108969 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 0 | 1 | 0 | 0 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.10150 | -0.923000 | -0.87110 | -1.483000 | -1.943000 | 0.33620 | 0.229600 | -0.32130 | -0.31720 | -0.96840 | -1.28400 | -1.15100 | -1.26800 | -1.205000 | -1.39900 | 2.1950 | 1.54900 | 2.1600 | 2.12700 | 0.95230 | -0.3313000 | -0.4062 | -0.70670 | 0.85050 | 1.090000 | -0.40480 | 0.458300 | LumB | NA | NA |
| X109623 | X109623 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -1.77200 | -2.232000 | -2.53000 | -2.028000 | -1.309000 | -1.51700 | -1.585000 | 0.23080 | -2.04900 | -1.16600 | -1.37400 | 0.74060 | 0.36590 | -1.197000 | -0.86970 | -0.4812 | 0.52240 | NA | NA | NA | 3.8050000 | NA | -1.74700 | 0.66270 | 1.731000 | 1.43900 | 0.432600 | LumA | NA | NA |
| X109874 | X109874 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.12610 | 0.568900 | 0.35200 | 0.722900 | 0.203500 | -0.24450 | 0.583700 | -0.30340 | -0.35630 | 0.62370 | 0.95030 | 1.29100 | 1.30000 | 0.726100 | 0.22670 | -0.5856 | -0.62310 | -0.3947 | -0.42990 | -0.38710 | -0.4627000 | -1.2890 | 1.18700 | -0.14400 | -1.535000 | -0.55090 | -1.044000 | Basal | UNS | LAR |
| X109980 | X109980 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 0 | 1 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.96250 | 0.812700 | 1.01400 | 0.665500 | 1.310000 | -0.42670 | 1.282000 | 1.12300 | -0.63020 | -0.86060 | -0.62060 | -0.17260 | -0.37090 | 0.925600 | -0.68740 | 2.1550 | 3.19000 | 6.2610 | 6.53300 | 0.59010 | 0.0381300 | -0.6191 | -1.06000 | 0.60440 | 1.434000 | 0.04486 | 0.505500 | LumB | NA | NA |
| X111004 | X111004 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Luminal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -0.21570 | 0.534000 | 0.29740 | 0.740600 | 0.913900 | 0.47210 | -0.424200 | 1.60100 | -0.89370 | -1.22400 | -0.77800 | 0.48380 | 0.12310 | 0.014020 | -0.38120 | -0.5555 | -1.17500 | -0.3340 | -0.38080 | 0.70050 | 0.3983000 | NA | 2.31800 | -1.44300 | -0.410600 | 0.40740 | -0.256300 | LumB | NA | NA |
| X111038 | X111038 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.30500 | 1.818000 | 1.45100 | 1.784000 | 1.898000 | 0.35760 | 0.803100 | -0.30500 | 0.61270 | 1.23500 | 1.17500 | -0.64410 | -0.27040 | 0.645000 | 0.10430 | -0.5796 | -0.56320 | -0.4160 | -0.31510 | 1.35700 | -1.2370000 | 0.4715 | -0.88780 | -1.55500 | -0.308700 | -1.12400 | -0.861600 | Basal | IM | BLIA |
| X111344 | X111344 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 1 | 0 | 1 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.16470 | 0.336100 | 0.18070 | 0.804400 | 2.632000 | -0.46240 | -0.011610 | -0.98070 | 0.31490 | 0.39010 | -1.05100 | -0.57770 | -0.42100 | -0.409600 | 0.08036 | -0.6016 | -0.62220 | -0.4043 | -0.41640 | 0.49830 | 0.0001858 | 0.6159 | -1.95600 | -0.21230 | 0.285900 | 0.63220 | 2.248000 | LumB | NA | NA |
| X111646 | X111646 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.36890 | -0.703600 | -0.41630 | -0.438700 | 0.796800 | -0.74150 | 0.262300 | 1.67100 | -0.87980 | -1.60500 | -1.30600 | -0.45840 | -0.80980 | -0.199800 | -0.86370 | -0.4250 | -0.46910 | NA | NA | NA | 1.2140000 | NA | 0.25080 | -0.55370 | 0.254300 | 1.58200 | 2.060000 | LumB | NA | NA |
| X111674 | X111674 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 1 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.23240 | -0.214500 | -0.01483 | 0.011390 | 0.195800 | 1.22300 | -0.499900 | 0.46760 | 0.29220 | 0.55540 | 0.90810 | 0.98660 | 1.01200 | 0.272300 | 1.13800 | -0.5113 | -0.32800 | -0.4779 | -0.56270 | -2.69100 | -0.4783000 | 9.2790 | 0.60930 | -0.20510 | -0.879600 | -0.82630 | -0.652500 | Basal | MSL | MES |
| X111881 | X111881 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 1 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.34970 | -0.216600 | -0.53990 | -0.268500 | 0.139100 | -1.58300 | -0.892400 | 0.46200 | 0.70120 | 0.72430 | -0.93820 | -1.03000 | -0.74060 | -0.076860 | -0.35420 | 2.2570 | 3.04100 | 3.4960 | 3.61400 | 0.70720 | -0.1055000 | -0.5253 | -0.08600 | 0.08368 | 0.482700 | 0.31460 | 0.233100 | LumB | NA | NA |
| X112606 | X112606 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trastuzumab | NA | NA | Ctr | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | 0.02571 | 0.159700 | -0.09021 | 0.010330 | -0.480800 | 0.40990 | 0.071040 | 0.99270 | -0.71140 | -1.09800 | -0.98030 | -3.14900 | -3.07900 | -0.537200 | -0.70060 | -0.4952 | 0.34880 | -0.2613 | -0.29810 | 0.62860 | 4.4520000 | -0.7779 | 1.15400 | -1.97400 | 0.199900 | 0.69400 | 2.501000 | LumA | NA | NA |
| X114087 | X114087 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -1.11700 | -1.409000 | -1.25100 | -0.820400 | 0.700700 | -1.52300 | -1.067000 | -0.26100 | -0.37050 | -0.72760 | -1.98400 | -1.11800 | -1.17900 | -1.218000 | 0.26500 | -0.6277 | -0.31540 | -0.3603 | -0.36150 | 0.37120 | 0.8584000 | NA | 0.03222 | -0.39490 | 0.122100 | 1.50900 | 2.133000 | LumB | NA | NA |
| X115638 | X115638 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.36310 | 0.158100 | 0.49560 | 0.805100 | 0.082480 | 0.78570 | 0.006451 | -1.35500 | 1.57100 | 0.89320 | 1.26800 | 0.14550 | 0.34750 | 0.013020 | 0.62470 | -0.6197 | -0.43430 | NA | NA | NA | -1.6680000 | NA | -2.19600 | 1.47900 | 0.274800 | -0.84600 | -0.772400 | Basal | IM | BLIA |
| X115987 | X115987 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 0 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2low/Immune-/DRD.v3- | HR-/HER2low/Immune-/DRD.v3- | -2.36500 | -2.138000 | -2.12400 | -2.721000 | -2.767000 | -0.14640 | -1.600000 | -0.70550 | 1.24000 | 0.81780 | 1.15500 | -0.09058 | 0.11860 | -2.030000 | 0.62820 | -0.1399 | -0.92390 | NA | NA | NA | -0.3328000 | NA | -0.23560 | 0.37530 | 0.442800 | -0.85720 | -1.030000 | Basal | M | BLIS |
| X116165 | X116165 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20900 | -0.333500 | 0.14560 | 0.040340 | 0.140200 | -0.56650 | 0.092170 | -0.53190 | 0.17420 | -0.45810 | -0.93540 | -0.81700 | -0.84440 | 0.678000 | -0.44900 | -0.4952 | -0.36510 | -0.1809 | -0.28000 | 3.76600 | 0.2887000 | NA | -0.72200 | -1.82000 | -0.647500 | 1.06500 | 1.511000 | LumB | NA | NA |
| X116603 | X116603 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 0 | 0 | 1 | 1 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.65710 | 0.212100 | 0.67640 | 0.794700 | 0.119800 | -0.42820 | -0.498600 | -1.72000 | 0.63850 | 1.15900 | 0.82100 | 0.05654 | 0.33430 | -0.527500 | 0.02534 | -0.1259 | -0.52070 | -0.2361 | -0.12090 | 1.92900 | -0.3574000 | 0.3903 | -1.36700 | 0.66130 | -0.401200 | -0.78980 | -1.155000 | Basal | UNS | BLIA |
| X117424 | X117424 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20130 | 0.023940 | -0.05377 | 0.333600 | 0.006988 | -0.25950 | -0.611200 | 0.38510 | 0.17090 | 0.69920 | 0.66920 | 1.12200 | 1.16900 | 0.822300 | 1.74100 | -0.5675 | -0.93290 | -0.3061 | -0.30020 | -0.03717 | -0.3578000 | -0.4342 | 1.17300 | 0.98710 | -0.170100 | -0.25300 | -0.690800 | Basal | MSL | LAR |
| X117707 | X117707 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 1 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.34680 | 0.770100 | 0.25000 | 0.650700 | 1.935000 | -0.77060 | -0.413700 | -1.13400 | 0.78900 | 0.95430 | 1.09400 | 0.19930 | 0.41040 | 0.065220 | 0.10800 | -0.5675 | -0.63500 | NA | NA | NA | -0.5770000 | NA | -0.75800 | 0.46640 | 0.134000 | -0.94430 | -0.934600 | Basal | BL1 | BLIS |
| X118307 | X118307 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | NA | NA | NA | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.29490 | -0.726600 | -0.22270 | -0.572000 | 0.327700 | -0.98270 | 0.360600 | -0.93590 | 1.01500 | 1.20200 | 1.08800 | 2.00500 | 2.07900 | 0.310300 | 1.24000 | -0.6237 | -0.58950 | -0.4582 | -0.40310 | 0.12270 | -0.6494000 | -1.4060 | -0.76410 | 0.75100 | -0.661400 | -0.62680 | -0.714900 | Basal | BL1 | BLIS |
| X119928 | X119928 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 0 | 0 | 1 | 1 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.25220 | 0.368100 | -0.49930 | 0.340400 | -0.424700 | -0.01930 | -0.482000 | -0.18170 | 1.28400 | 1.03000 | 0.49500 | -0.22080 | 0.05538 | -1.117000 | 1.27900 | -0.5836 | -1.18800 | NA | NA | NA | -1.6050000 | NA | 0.41000 | 0.67130 | 0.976700 | -0.39070 | -1.037000 | Basal | BL2 | LAR |
| X120001 | X120001 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 0 | 0 | 0 | 0 | 0 | 0 | Basal-type | TN | TN/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -0.96740 | -0.349700 | -0.35340 | -0.048590 | 0.915500 | -0.38410 | -0.624100 | -1.02500 | 1.01300 | 0.50510 | 0.93620 | -0.79060 | -0.58180 | -0.629800 | 0.64760 | -0.5515 | -0.59680 | -0.4545 | -0.43160 | -0.76680 | -0.2782000 | -0.2686 | 0.17130 | -1.24200 | -0.572300 | -0.59590 | -0.582600 | Basal | BL1 | BLIS |
| X120422 | X120422 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.37600 | 1.118000 | 1.15300 | 0.250200 | -0.468100 | 2.55500 | 1.414000 | -0.02934 | 0.48120 | 0.55180 | 1.13000 | 2.08500 | 1.98900 | 1.330000 | 2.90300 | -0.5434 | -0.98200 | NA | NA | NA | -0.4173000 | NA | 0.84000 | 0.36400 | -1.065000 | -0.66330 | -0.510900 | Basal | NA | NA |
| X122287 | X122287 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 1 | 1 | 1 | 1 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.65590 | 0.433900 | 0.20350 | 0.461600 | 0.791700 | -0.35650 | 0.553700 | 0.76490 | -0.60180 | 0.01271 | -0.51100 | 1.24200 | 1.10500 | 0.338800 | -0.38710 | 2.2610 | 2.72200 | 1.5160 | 2.01800 | -0.40390 | -0.9569000 | NA | 0.56190 | -1.09200 | -2.047000 | -0.95550 | -0.926500 | Her2 | NA | NA |
| X122579 | X122579 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | 0.35360 | -0.023670 | 0.02669 | 0.373700 | 0.543700 | -0.35840 | -0.517000 | 0.33200 | -0.94680 | -1.16200 | -1.27300 | -1.35300 | -1.49600 | 0.740500 | -1.50700 | -0.4370 | -0.25600 | -0.3575 | -0.38600 | 0.17210 | -1.1870000 | NA | -0.88580 | -0.74200 | 0.653100 | 1.07100 | 0.545900 | LumB | NA | NA |
| X122795 | X122795 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.02600 | 0.918500 | 0.85100 | -0.147900 | -0.983600 | 0.62740 | 1.071000 | 1.05400 | -1.67400 | -2.21900 | 0.86320 | -0.21630 | -0.74690 | 0.454000 | -1.00100 | -0.6036 | -0.88950 | NA | NA | NA | 0.1935000 | NA | 2.03200 | 0.16340 | -0.105200 | -0.38230 | -0.316300 | Normal | MSL | LAR |
| X123660 | X123660 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trastuzumab | NA | NA | Ctr | 0 | 0 | 1 | 0 | 0 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.93020 | -1.299000 | -0.71420 | -0.901100 | -0.427300 | -0.56650 | -0.537800 | 0.19560 | -1.47300 | -0.86060 | -0.87920 | 1.76600 | 1.35400 | -0.807600 | 0.23710 | 2.2410 | 1.59200 | 2.2400 | 2.83400 | 0.47630 | -0.1896000 | 1.5030 | 0.62890 | -0.29760 | -0.938000 | -0.50310 | 0.005983 | LumA | NA | NA |
| X125130 | X125130 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 0 | 1 | 1 | 1 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 1.19800 | 0.561800 | 0.65390 | 0.191900 | -0.451200 | -0.27830 | 1.558000 | -0.63220 | 0.59220 | 0.44400 | 0.38260 | 0.84720 | 0.86040 | 0.915500 | -0.04674 | 1.8110 | 1.43200 | 0.2868 | 0.30950 | -0.13690 | -1.3940000 | NA | -0.94240 | -0.01876 | 0.077300 | -1.01700 | -1.372000 | Her2 | NA | NA |
| X125385 | X125385 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 0 | 1 | 0 | 0 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.63910 | -1.139000 | -0.85850 | -1.245000 | -1.514000 | -0.30730 | 0.031980 | 0.34490 | -0.91440 | -1.28100 | -1.70000 | 0.54690 | 0.16500 | -0.443400 | -2.53400 | -0.5715 | 0.06301 | -0.3253 | -0.35040 | 0.86900 | 2.0510000 | -0.4205 | -1.02700 | 1.25200 | 0.337700 | 1.32900 | 1.500000 | LumA | NA | NA |
| X125418 | X125418 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Luminal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -1.09300 | -0.781700 | -0.48760 | -1.263000 | -0.745800 | 0.66220 | -0.940000 | 0.90980 | -1.72800 | -1.69800 | -0.73020 | -0.57590 | -0.93760 | -1.322000 | -0.60520 | -0.4129 | -0.34090 | NA | NA | NA | 0.6096000 | NA | 1.03100 | -0.18380 | -1.279000 | 0.64060 | 0.453100 | LumA | NA | NA |
| X127675 | X127675 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.29300 | 0.828500 | 1.17000 | 1.745000 | 1.624000 | 0.97350 | 0.749700 | -0.11100 | 0.12930 | 0.55900 | 1.36100 | 1.04200 | 1.06200 | 1.089000 | 0.08196 | -0.5394 | -0.38720 | -0.4157 | -0.34910 | -0.13850 | -1.1260000 | -0.3617 | 0.01659 | 0.09648 | -1.786000 | -0.98080 | -1.320000 | Basal | IM | BLIA |
| X127791 | X127791 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pertuzumab + Trastuzumab | NA | NA | Pertuzumab | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.96240 | -1.167000 | -1.17000 | -1.429000 | -1.249000 | -0.87150 | -1.027000 | 1.07100 | -0.19110 | -0.35390 | -0.71900 | 0.18000 | 0.06864 | -0.548700 | 0.54290 | 1.1550 | 0.36820 | 0.8130 | 0.56430 | -0.76900 | -1.4000000 | NA | 0.73710 | 1.40700 | 1.543000 | 0.56470 | 0.973900 | Her2 | NA | NA |
| X128051 | X128051 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.34930 | -0.172200 | -0.38640 | -0.372300 | -0.822200 | -0.10920 | -0.812100 | 0.54510 | 0.44580 | -0.15260 | -0.88760 | -1.47800 | -1.35700 | -0.565100 | 0.28400 | -0.5193 | 0.02209 | -0.2318 | -0.16740 | 0.72870 | 0.3469000 | NA | -0.17310 | 0.25870 | 1.562000 | 0.89070 | 0.861800 | LumB | NA | NA |
| X128675 | X128675 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 1 | 1 | 0 | 1 | 0 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | HR+HER2-/BP_Basal/Immune- | NA | NA | NA | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | -0.62740 | -0.351800 | -0.42330 | 0.274300 | -1.267000 | -0.03677 | -1.007000 | -0.66710 | 1.06900 | 0.92560 | 0.80980 | 1.71500 | 1.75200 | 0.504300 | 0.31440 | -0.5314 | -0.43710 | 0.8261 | 1.32400 | -0.88480 | -1.1300000 | NA | -0.31700 | -0.57750 | -1.632000 | -0.83470 | -1.198000 | Basal | NA | NA |
| X129837 | X129837 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 0 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.18490 | 0.129000 | -0.23280 | -0.451700 | -0.509000 | -0.05867 | 0.347200 | -0.05933 | 0.18520 | 0.59490 | 0.86880 | 1.24000 | 1.24700 | 0.347700 | 1.07100 | -0.1700 | -0.51200 | -0.3427 | -0.37730 | 1.39500 | 0.4459000 | 0.1942 | -0.27040 | 0.18330 | -0.622500 | -0.97520 | -0.613900 | Basal | UNS | LAR |
| X129973 | X129973 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.97090 | 1.241000 | 1.36000 | 1.097000 | 2.024000 | 0.70750 | 0.982700 | -0.39490 | 0.04194 | 1.07300 | 0.91940 | 1.61200 | 1.69700 | 1.653000 | 0.25600 | -0.2885 | -0.19200 | -0.2391 | -0.26100 | -0.26380 | -0.8008000 | -0.3734 | -0.96000 | 0.57030 | -0.542900 | -1.14900 | -0.728100 | Basal | IM | BLIA |
| X130580 | X130580 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.40270 | 0.485400 | 0.30520 | 0.581100 | 0.640000 | 0.37530 | 0.135700 | -0.05388 | 0.57870 | 0.72430 | 1.33200 | 0.41440 | 0.54480 | 0.189300 | -0.06618 | -0.5936 | -0.25670 | NA | NA | NA | -0.1167000 | NA | -0.46390 | 0.69260 | -0.853700 | -0.90780 | -0.282100 | Basal | BL1 | MES |
| X130892 | X130892 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 | NA | NA | MK2206 | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.01530 | 0.007158 | 0.41820 | 0.764500 | 1.249000 | -0.53860 | 0.188800 | -0.01742 | -0.53720 | 0.55540 | 0.45290 | 0.63570 | 0.69970 | 0.331200 | -1.00400 | -0.6338 | -0.59650 | -0.3888 | -0.32540 | 0.24290 | -0.4053000 | -0.6858 | -0.56700 | 0.78080 | 0.004152 | -0.88810 | -0.807900 | NA | NA | NA |
| X131595 | X131595 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 1 | 0 | 0 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.55200 | 1.614000 | 1.13400 | 1.811000 | 1.674000 | 0.18230 | 0.439100 | 0.72770 | 0.97930 | -0.27480 | -0.38740 | -1.59200 | -1.48800 | 0.973700 | -0.14340 | -0.6297 | -0.89290 | -0.4776 | -0.34710 | 1.27500 | -0.4092000 | -0.9520 | -0.97060 | -0.01307 | 1.277000 | 0.88230 | 1.506000 | LumB | NA | NA |
| X131961 | X131961 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 1 | 1 | 0 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -1.78200 | -1.909000 | -1.70800 | -1.331000 | 0.155800 | -1.03700 | -1.197000 | 0.10620 | -0.66920 | -0.22450 | -1.00800 | -0.61710 | -0.60850 | -1.644000 | 0.02262 | 2.2290 | 2.78800 | 0.3577 | 0.09546 | -0.94310 | 0.1774000 | NA | 1.63400 | -0.39150 | -0.294200 | 0.17690 | -0.359600 | Her2 | NA | NA |
Microarray Expression Data
Display first 20 rows of quantile-normalized Microarray data
# Display the first 20 rows
kable(head(expr, 20), caption = "Expression Data-Microarray") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| X756412 | X111881 | X451816 | X243836 | X402265 | X611662 | X139137 | X685753 | X627981 | X108939 | X629210 | X809037 | X107700 | X373672 | X615873 | X607047 | X155171 | X815421 | X605713 | X246134 | X373346 | X349225 | X208265 | X395076 | X637752 | X331192 | X327133 | X541165 | X802778 | X794428 | X625800 | X422450 | X613188 | X120001 | X166412 | X672734 | X828199 | X708387 | X229824 | X851180 | X587388 | X277848 | X517446 | X227832 | X495440 | X141782 | X972307 | X540539 | X891645 | X591180 | X766301 | X614044 | X284355 | X961350 | X894491 | X233962 | X552313 | X415039 | X930853 | X930172 | X489973 | X709559 | X714205 | X635862 | X519738 | X924812 | X604380 | X973837 | X375455 | X655703 | X646233 | X367682 | X108969 | X153880 | X849605 | X997702 | X706943 | X726091 | X568331 | X348009 | X160120 | X596079 | X125385 | X920479 | X789497 | X282644 | X484867 | X564234 | X139771 | X420523 | X654956 | X145513 | X957408 | X520258 | X876511 | X872188 | X388581 | X833536 | X227881 | X683374 | X771813 | X225836 | X181819 | X460776 | X840501 | X932200 | X267306 | X129837 | X239061 | X974618 | X797427 | X197942 | X111038 | X597253 | X491526 | X157463 | X570148 | X151230 | X666450 | X570380 | X255388 | X127675 | X790722 | X477816 | X298101 | X632408 | X835137 | X803514 | X202956 | X362993 | X809649 | X220664 | X941191 | X414286 | X697871 | X496205 | X284593 | X248255 | X771443 | X889049 | X531672 | X641246 | X894128 | X578975 | X335091 | X406190 | X781335 | X628692 | X580632 | X783578 | X910706 | X782334 | X836114 | X944419 | X159352 | X374121 | X573881 | X676048 | X178649 | X245655 | X553141 | X382853 | X778020 | X885590 | X443708 | X622078 | X627118 | X916645 | X427321 | X581648 | X903880 | X913225 | X201873 | X345574 | X953262 | X357017 | X380239 | X178815 | X575372 | X922433 | X350331 | X527320 | X791944 | X728182 | X183831 | X264678 | X962472 | X515141 | X411684 | X198891 | X573586 | X316996 | X190224 | X461824 | X479417 | X906042 | X988443 | X180027 | X845663 | X134526 | X623086 | X814299 | X211408 | X286984 | X733962 | X192548 | X255078 | X515105 | X273745 | X374106 | X890414 | X563856 | X222135 | X349639 | X386664 | X651541 | X426106 | X122795 | X729270 | X697098 | X942017 | X307659 | X677915 | X233832 | X994987 | X360937 | X590220 | X405717 | X640463 | X650589 | X291515 | X955953 | X340186 | X640927 | X109980 | X489504 | X234272 | X259206 | X904269 | X507198 | X800710 | X255535 | X725455 | X698094 | X934459 | X478484 | X166782 | X435313 | X202539 | X306127 | X129973 | X959366 | X228340 | X539291 | X572731 | X572235 | X946927 | X596458 | X835658 | X660915 | X318569 | X819622 | X600536 | X566011 | X318438 | X422013 | X663467 | X188511 | X573919 | X602943 | X378401 | X859699 | X188091 | X111674 | X511851 | X229144 | X812089 | X749097 | X437968 | X728714 | X395379 | X294176 | X299364 | X303947 | X766967 | X726381 | X592535 | X443444 | X962827 | X775346 | X515565 | X442637 | X238790 | X327142 | X262131 | X169536 | X151481 | X630758 | X549172 | X174903 | X680881 | X790070 | X889225 | X723918 | X742477 | X579881 | X203254 | X423619 | X154293 | X746731 | X282082 | X433144 | X883886 | X223526 | X520471 | X172283 | X720065 | X451482 | X417654 | X234723 | X883696 | X117424 | X380769 | X572444 | X925691 | X765671 | X836983 | X746265 | X287300 | X944536 | X112606 | X598798 | X960963 | X376676 | X950742 | X289420 | X641977 | X326433 | X539876 | X622315 | X366120 | X769972 | X547405 | X918979 | X845783 | X767081 | X464547 | X884011 | X949444 | X797639 | X264305 | X277888 | X753109 | X220471 | X266840 | X378885 | X220925 | X131595 | X604199 | X947398 | X689480 | X146033 | X564701 | X641697 | X522140 | X413211 | X306401 | X571995 | X506623 | X498985 | X172168 | X786003 | X663144 | X960029 | X618717 | X152090 | X460642 | X515281 | X414844 | X848003 | X131961 | X795996 | X683457 | X105513 | X518000 | X501303 | X139973 | X778527 | X345907 | X963604 | X861745 | X860901 | X724384 | X621179 | X568953 | X779739 | X863161 | X679787 | X910188 | X401215 | X345460 | X999733 | X285339 | X572793 | X843554 | X467622 | X798604 | X890372 | X208650 | X532183 | X432114 | X474874 | X651145 | X614434 | X521860 | X215932 | X793155 | X618240 | X490805 | X239910 | X294265 | X199960 | X227055 | X786753 | X253531 | X590299 | X580541 | X654064 | X791321 | X422454 | X213672 | X929391 | X477994 | X913527 | X259899 | X676630 | X894673 | X870077 | X866660 | X685795 | X218503 | X802308 | X741535 | X362150 | X317402 | X188700 | X547892 | X738041 | X900959 | X130892 | X893874 | X618860 | X628788 | X504838 | X794128 | X882553 | X732137 | X332655 | X845147 | X535415 | X851223 | X342959 | X971492 | X269899 | X729732 | X635632 | X509012 | X991818 | X290413 | X319324 | X157270 | X748611 | X689076 | X587604 | X601489 | X917762 | X516834 | X607843 | X318407 | X689452 | X712917 | X609151 | X145777 | X254060 | X491779 | X180663 | X293142 | X706639 | X563681 | X409288 | X774840 | X301665 | X783427 | X831848 | X323721 | X275626 | X296123 | X237158 | X906795 | X212307 | X229328 | X327917 | X887594 | X661730 | X156163 | X202535 | X399478 | X418593 | X200222 | X555214 | X296841 | X683896 | X356431 | X879224 | X752469 | X116603 | X664111 | X760901 | X165925 | X430441 | X329941 | X820348 | X748583 | X201831 | X938719 | X728287 | X275034 | X219545 | X982086 | X102212 | X721099 | X397505 | X109874 | X896852 | X535569 | X965265 | X992609 | X653927 | X318293 | X150547 | X111344 | X797499 | X639663 | X768214 | X294739 | X691753 | X539904 | X453596 | X118307 | X825363 | X955035 | X179568 | X280375 | X924895 | X706169 | X760011 | X221686 | X355942 | X104268 | X780272 | X800447 | X335536 | X125130 | X402384 | X896621 | X301968 | X567907 | X412772 | X356684 | X856159 | X862244 | X254273 | X690089 | X416434 | X598835 | X839274 | X136536 | X882538 | X439489 | X987914 | X437162 | X284443 | X923968 | X115987 | X804979 | X105286 | X144302 | X552549 | X411950 | X435279 | X204939 | X688955 | X700549 | X328160 | X228192 | X875089 | X462582 | X196064 | X829491 | X801641 | X213913 | X414971 | X573605 | X103939 | X824512 | X928446 | X631337 | X516763 | X685182 | X317641 | X587691 | X174904 | X695521 | X899692 | X172366 | X329076 | X146987 | X905264 | X655128 | X309830 | X653325 | X929980 | X712276 | X649198 | X974181 | X299962 | X417474 | X851488 | X535779 | X263143 | X209967 | X343898 | X531988 | X963303 | X631299 | X987995 | X624777 | X637566 | X755914 | X363669 | X345483 | X261304 | X727804 | X654021 | X203060 | X820807 | X604326 | X688291 | X530095 | X705381 | X396723 | X677910 | X666147 | X179369 | X982505 | X375954 | X320538 | X266509 | X100899 | X803677 | X799149 | X182346 | X943633 | X429220 | X901705 | X712785 | X845079 | X330134 | X771151 | X629371 | X169918 | X570966 | X745633 | X734997 | X792181 | X467686 | X287961 | X520986 | X252748 | X454808 | X597907 | X790397 | X987728 | X609642 | X889721 | X465008 | X865416 | X493519 | X138027 | X788149 | X823618 | X317131 | X383456 | X834418 | X123660 | X736721 | X233191 | X407539 | X895653 | X824234 | X283070 | X542392 | X413961 | X130580 | X375342 | X490023 | X787415 | X885871 | X728149 | X995480 | X528833 | X408692 | X805136 | X132463 | X726940 | X517870 | X652480 | X199115 | X783764 | X752372 | X808714 | X928815 | X241705 | X148357 | X591810 | X411008 | X162562 | X687288 | X120422 | X898618 | X628823 | X349330 | X524170 | X240957 | X584561 | X421917 | X115638 | X928170 | X223030 | X970839 | X507249 | X724293 | X796558 | X384830 | X586207 | X559021 | X962153 | X711476 | X361701 | X924071 | X241998 | X109623 | X111646 | X515284 | X196024 | X221375 | X847272 | X916586 | X786480 | X452703 | X167271 | X884266 | X498024 | X279902 | X551795 | X240035 | X613961 | X342142 | X554577 | X570685 | X986734 | X999264 | X988665 | X494022 | X623569 | X493775 | X355292 | X767934 | X571276 | X528479 | X981664 | X102011 | X689188 | X164468 | X483667 | X273691 | X250274 | X527581 | X410083 | X830486 | X510543 | X690410 | X550421 | X119928 | X550157 | X122287 | X518576 | X300724 | X674897 | X943879 | X567201 | X411806 | X575457 | X138425 | X810965 | X901807 | X208303 | X282777 | X930903 | X912836 | X572016 | X395249 | X759418 | X313243 | X687733 | X831702 | X268937 | X473468 | X676365 | X591079 | X125418 | X719713 | X342996 | X419590 | X924868 | X877463 | X846156 | X983841 | X466267 | X455828 | X380972 | X953885 | X133650 | X377460 | X151980 | X765773 | X240432 | X462605 | X536253 | X442669 | X860243 | X472799 | X117707 | X781642 | X493472 | X966016 | X127791 | X235995 | X824350 | X941926 | X914968 | X703455 | X981461 | X313672 | X637051 | X733276 | X357034 | X324021 | X236470 | X706418 | X646600 | X456432 | X727255 | X644609 | X459311 | X311316 | X128051 | X460812 | X503034 | X589502 | X462581 | X940186 | X602451 | X793684 | X414256 | X559263 | X666715 | X159284 | X153327 | X581180 | X494296 | X425173 | X255577 | X213328 | X494946 | X873686 | X104384 | X436371 | X311455 | X802105 | X257735 | X122579 | X168044 | X247641 | X703401 | X804233 | X484894 | X242370 | X356399 | X371528 | X177795 | X658541 | X391942 | X489194 | X473505 | X935460 | X181442 | X896939 | X289107 | X848371 | X478055 | X347516 | X369040 | X651401 | X899381 | X218249 | X423979 | X668752 | X116165 | X934906 | X815493 | X103693 | X502486 | X114087 | X301289 | X442981 | X847753 | X553012 | X142688 | X353318 | X640043 | X111004 | X830958 | X636424 | X152197 | X485637 | X149654 | X857165 | X421829 | X341238 | X655795 | X660534 | X692885 | X424541 | X841336 | X497010 | X128675 | X478655 | X990443 | X231633 | X892390 | X597873 | X574091 | X483910 | X326202 | X456506 | X922872 | X625854 | X735673 | X543795 | X431061 | X683173 | X664658 | X473365 | X622688 | X783771 | X303685 | X960490 | X333145 | X701790 | X616994 | X458196 | X209397 | X299840 | X147139 | X446263 | X500826 | X194024 | X832056 | X663197 | X644186 | X962664 | X950131 | X492612 | X792412 | X586091 | X629606 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TSPAN6 | 9.2058 | 7.5586 | 7.0909 | 8.8402 | 8.7008 | 8.3078 | 8.8128 | 9.2206 | 9.1506 | 8.9980 | 8.2162 | 10.2200 | 9.5105 | 10.2290 | 10.4370 | 7.4639 | 7.6933 | 9.8551 | 8.2288 | 8.3604 | 9.0722 | 9.4142 | 10.5580 | 9.1585 | 10.4630 | 8.8212 | 9.6225 | 10.0520 | 10.1200 | 6.0160 | 7.8679 | 10.0020 | 9.4689 | 10.3340 | 7.9905 | 9.0964 | 10.2320 | 9.5162 | 7.9447 | 8.1289 | 9.0654 | 9.1674 | 8.3009 | 9.7609 | 9.5831 | 9.6604 | 7.9505 | 10.1110 | 8.5840 | 11.1040 | 8.0384 | 9.0806 | 8.5629 | 9.0648 | 8.3341 | 9.5983 | 8.6734 | 8.7713 | 7.9705 | 9.3474 | 8.7928 | 9.0696 | 9.4847 | 9.1495 | 8.5193 | 9.1248 | 9.0107 | 7.8832 | 9.0506 | 7.5596 | 8.3583 | 8.3904 | 9.9072 | 8.9996 | 10.3850 | 10.2090 | 8.9665 | 8.7334 | 10.1070 | 8.9307 | 10.3790 | 8.9544 | 10.6210 | 8.7865 | 8.8586 | 8.7313 | 9.3868 | 8.7629 | 9.3005 | 9.7446 | 9.3505 | 8.3109 | 7.6954 | 9.0022 | 9.9119 | 9.7241 | 9.7388 | 10.1780 | 8.3814 | 8.9538 | 9.4852 | 8.7681 | 8.1157 | 7.6617 | 10.1630 | 9.9887 | 10.8330 | 9.1238 | 10.0360 | 8.1778 | 7.9095 | 10.0420 | 9.4542 | 9.3731 | 7.6943 | 8.8212 | 7.6070 | 9.1469 | 7.7280 | 9.5704 | 9.3895 | 8.2909 | 8.4393 | 10.8270 | 7.3818 | 8.7055 | 7.4912 | 8.8039 | 9.1169 | 10.0140 | 8.8349 | 9.2253 | 9.1911 | 9.6772 | 10.3770 | 10.1590 | 9.9308 | 8.8002 | 8.5503 | 10.1820 | 7.8695 | 8.9517 | 9.1153 | 9.7104 | 7.9642 | 8.7976 | 8.3893 | 9.5762 | 10.0270 | 10.5430 | 9.3479 | 8.7928 | 9.5173 | 9.6209 | 8.7423 | 10.1900 | 8.6450 | 10.0080 | 9.5541 | 9.0548 | 7.4186 | 10.5120 | 9.3805 | 9.6067 | 9.7351 | 9.6094 | 8.6908 | 8.9517 | 9.0228 | 9.7640 | 8.7876 | 8.8875 | 8.8007 | 9.7556 | 8.8981 | 8.0952 | 10.0040 | 9.0333 | 9.1064 | 9.7709 | 9.5189 | 8.9459 | 7.9616 | 8.3767 | 9.3063 | 7.7916 | 8.3725 | 9.3653 | 9.5326 | 8.0899 | 9.6946 | 8.7202 | 7.1471 | 8.1441 | 9.5299 | 8.9028 | 8.5477 | 9.2106 | 8.7913 | 8.8860 | 10.3020 | 8.2599 | 7.8479 | 9.5783 | 8.2509 | 9.2548 | 8.9380 | 9.0043 | 7.4470 | 9.6783 | 8.3662 | 10.2650 | 9.6741 | 7.5233 | 8.4661 | 8.6729 | 8.6266 | 9.1132 | 8.3120 | 9.7530 | 10.1530 | 8.6492 | 10.1550 | 8.5429 | 7.5738 | 8.4556 | 9.4089 | 11.1960 | 9.9529 | 9.3931 | 9.7619 | 9.6025 | 9.3132 | 10.6180 | 8.0294 | 8.5666 | 7.2429 | 9.3579 | 9.3537 | 9.7057 | 11.0330 | 8.1384 | 9.6483 | 10.0700 | 10.4900 | 9.6078 | 8.7087 | 9.6257 | 9.0591 | 7.1387 | 7.6212 | 9.9745 | 8.2488 | 9.6557 | 9.2811 | 9.5536 | 9.9035 | 7.0446 | 9.5773 | 9.5652 | 8.5440 | 9.6073 | 10.0280 | 10.1710 | 11.0740 | 9.2511 | 8.8002 | 6.5537 | 10.2710 | 9.6246 | 9.5999 | 9.6441 | 8.4314 | 9.7341 | 9.4863 | 7.7075 | 9.7383 | 8.2599 | 9.0075 | 9.8530 | 8.9586 | 8.7639 | 8.0910 | 8.9607 | 7.3292 | 8.7634 | 10.0570 | 8.7113 | 9.6699 | 8.4409 | 9.4615 | 8.9096 | 9.2727 | 7.9279 | 9.6967 | 8.9007 | 9.7304 | 9.3495 | 9.1196 | 8.5524 | 10.5720 | 9.5415 | 7.7143 | 9.3547 | 9.3121 | 8.4993 | 11.1640 | 9.4600 | 9.4089 | 10.1790 | 9.6625 | 10.8500 | 8.7713 | 9.2127 | 9.5778 | 9.8340 | 8.3330 | 8.7276 | 9.2706 | 8.5440 | 9.2716 | 10.5270 | 9.6693 | 8.4914 | 9.1911 | 8.6082 | 8.5172 | 9.2211 | 8.7176 | 8.1499 | 9.6604 | 7.8848 | 7.3697 | 8.6456 | 7.2244 | 9.2447 | 8.8816 | 8.4441 | 7.9705 | 10.1370 | 9.5246 | 6.6000 | 9.7650 | 9.7120 | 10.2130 | 9.1454 | 8.6062 | 7.8990 | 9.2764 | 8.9999 | 10.1410 | 6.8667 | 9.3022 | 8.2820 | 9.0642 | 8.1579 | 9.2832 | 7.6264 | 7.8017 | 9.5178 | 7.3286 | 8.6490 | 9.1965 | 8.3876 | 7.1870 | 8.1915 | 8.5706 | 10.6070 | 8.0212 | 8.3044 | 9.6166 | 8.8052 | 8.5108 | 7.6503 | 8.0981 | 10.9950 | 8.6402 | 8.3750 | 7.3057 | 10.4550 | 9.1085 | 8.8228 | 10.4430 | 8.6329 | 9.5436 | 8.6621 | 8.0022 | 9.4852 | 9.0656 | 8.1190 | 8.7872 | 10.3780 | 9.6341 | 8.3356 | 7.6435 | 9.2009 | 9.0189 | 8.3570 | 9.3445 | 7.3948 | 8.4626 | 9.0559 | 9.8935 | 8.8310 | 9.9081 | 9.0861 | 9.4521 | 10.2230 | 7.0585 | 9.2924 | 10.9810 | 9.2496 | 9.5888 | 8.8296 | 8.9439 | 9.7670 | 10.1310 | 9.5037 | 8.5799 | 9.5513 | 8.9795 | 8.5322 | 8.9508 | 8.6013 | 8.9902 | 9.1235 | 8.0022 | 9.7665 | 9.4652 | 8.3468 | 8.8344 | 8.3044 | 9.8487 | 9.2082 | 11.5310 | 9.4988 | 9.4569 | 8.9493 | 8.3643 | 8.3171 | 9.5825 | 9.9392 | 8.4071 | 8.8768 | 8.7843 | 9.8984 | 9.1143 | 8.1910 | 6.4608 | 8.6305 | 8.6986 | 8.4207 | 9.7047 | 9.3270 | 9.3484 | 8.4772 | 9.0715 | 9.1031 | 7.8800 | 8.6388 | 9.5358 | 10.8000 | 8.4358 | 8.7502 | 7.8927 | 8.1058 | 11.4710 | 10.0300 | 9.3766 | 9.1897 | 7.5364 | 9.9607 | 7.0750 | 10.2400 | 9.3698 | 7.8664 | 7.8795 | 8.4524 | 9.1503 | 8.9902 | 9.0121 | 8.4451 | 8.3263 | 9.0598 | 8.0377 | 8.8393 | 7.4741 | 8.2845 | 10.2060 | 9.0778 | 8.9104 | 8.3546 | 8.1628 | 8.3803 | 8.7999 | 9.7378 | 8.7035 | 9.6214 | 8.5546 | 8.5380 | 8.1803 | 9.7670 | 8.8933 | 9.5421 | 9.6467 | 8.6261 | 9.7582 | 9.8181 | 8.4212 | 9.5041 | 8.8967 | 7.3812 | 9.4326 | 9.3138 | 9.3309 | 10.6720 | 7.6488 | 9.4112 | 10.4310 | 8.4256 | 9.3708 | 9.0734 | 7.3330 | 9.4097 | 8.1691 | 7.8596 | 8.7191 | 9.9232 | 9.8487 | 8.9819 | 9.6000 | 9.4964 | 8.9532 | 8.7264 | 8.9045 | 9.6662 | 9.6565 | 9.3464 | 8.3482 | 9.1746 | 8.3458 | 8.5468 | 10.3070 | 9.6351 | 8.9600 | 8.1954 | 8.5268 | 8.6417 | 9.3727 | 9.6034 | 9.4282 | 9.3455 | 8.9157 | 9.5713 | 8.7055 | 8.5702 | 8.9951 | 10.1290 | 8.9016 | 8.7025 | 9.2798 | 9.0204 | 10.3830 | 9.5932 | 8.6266 | 8.5624 | 8.3458 | 11.7560 | 10.5100 | 8.8052 | 9.7757 | 9.3635 | 11.2900 | 10.0050 | 8.6232 | 8.4388 | 8.3833 | 9.1610 | 8.8291 | 9.5874 | 10.1850 | 9.0014 | 8.3536 | 11.0500 | 9.8400 | 9.3338 | 8.8291 | 9.4039 | 9.2642 | 8.6188 | 9.4292 | 10.8760 | 9.0841 | 8.5361 | 9.3299 | 10.2020 | 8.8432 | 10.1720 | 8.9109 | 8.5750 | 9.3810 | 10.4640 | 9.4452 | 9.3318 | 8.7799 | 9.3640 | 9.5338 | 8.5113 | 7.9968 | 8.9065 | 9.3688 | 9.2111 | 7.9399 | 10.2650 | 10.6730 | 9.9641 | 8.4271 | 8.7736 | 8.6879 | 9.1172 | 8.0684 | 10.2550 | 9.5737 | 8.4913 | 9.4404 | 9.2851 | 9.4068 | 8.7454 | 9.6901 | 9.4681 | 7.4965 | 9.4180 | 9.6049 | 9.1313 | 9.3328 | 9.3250 | 9.1459 | 9.6355 | 9.3187 | 8.8641 | 9.7874 | 8.8490 | 8.4996 | 10.5630 | 9.4292 | 7.0663 | 8.1248 | 10.7860 | 9.0165 | 7.7764 | 7.7968 | 9.4477 | 7.3554 | 9.0184 | 6.5401 | 11.2210 | 9.8054 | 8.7089 | 7.9443 | 9.3143 | 8.7332 | 8.2927 | 9.7728 | 9.4516 | 7.6537 | 9.6784 | 9.5694 | 8.4169 | 8.8383 | 9.3508 | 9.0807 | 8.6222 | 8.4222 | 7.8800 | 8.5770 | 7.4658 | 9.2472 | 10.0200 | 10.5450 | 9.9831 | 9.7363 | 8.3784 | 9.5095 | 9.0058 | 8.7926 | 10.2600 | 8.4582 | 6.9397 | 9.8989 | 8.7780 | 7.6518 | 9.9461 | 8.5814 | 6.3532 | 9.4438 | 9.4657 | 10.1040 | 9.2170 | 8.6904 | 8.5444 | 9.0685 | 10.4140 | 9.6273 | 9.3382 | 9.9212 | 9.1995 | 8.8544 | 9.6905 | 9.0856 | 8.2806 | 7.2069 | 9.7246 | 10.8270 | 9.0500 | 9.6652 | 9.7772 | 8.3487 | 7.6016 | 8.6529 | 9.3143 | 8.7634 | 10.7050 | 8.2927 | 7.5403 | 8.4791 | 10.2110 | 8.3205 | 8.7347 | 10.2410 | 8.1876 | 10.2720 | 10.1960 | 7.7764 | 8.0474 | 8.9887 | 10.0580 | 9.4715 | 9.1712 | 10.3000 | 9.8852 | 9.0165 | 8.1978 | 9.1591 | 7.8309 | 9.0564 | 10.2650 | 9.7455 | 9.0539 | 7.0911 | 9.1231 | 11.3480 | 8.4563 | 7.8562 | 8.9454 | 9.8044 | 9.2257 | 10.6210 | 8.2635 | 11.6710 | 9.2447 | 9.5913 | 8.3570 | 8.6183 | 9.7772 | 9.3387 | 8.8977 | 9.9670 | 9.0841 | 9.8852 | 8.2650 | 8.9352 | 9.7947 | 8.5560 | 8.6738 | 10.4260 | 9.4443 | 7.7734 | 9.7519 | 9.8039 | 10.2600 | 10.1450 | 9.7553 | 9.3275 | 11.9190 | 7.9905 | 9.0953 | 8.9824 | 9.0150 | 9.6482 | 9.7358 | 8.3020 | 8.5551 | 9.5012 | 10.7770 | 8.9882 | 9.3980 | 9.8331 | 8.6733 | 10.2860 | 9.8069 | 9.7850 | 8.6154 | 10.4310 | 8.9269 | 8.9084 | 9.3426 | 8.0445 | 8.8271 | 9.3406 | 9.0403 | 9.0622 | 9.9451 | 8.7571 | 8.9800 | 9.0072 | 8.3492 | 8.3463 | 9.1844 | 11.6290 | 9.3489 | 8.7303 | 8.5366 | 7.2283 | 10.0980 | 9.6808 | 10.1530 | 10.3600 | 8.6573 | 8.6938 | 8.9401 | 9.0062 | 9.0895 | 8.8763 | 9.4253 | 10.3630 | 9.7339 | 9.6312 | 10.1660 | 8.6923 | 9.2895 | 8.8529 | 9.1094 | 10.0230 | 9.2126 | 10.1380 | 9.5937 | 9.1016 | 7.2332 | 9.2447 | 8.7736 | 10.0680 | 9.1805 | 8.0513 | 7.9632 | 8.5930 | 11.1020 | 8.9045 | 9.2126 | 9.8945 | 10.0820 | 8.7463 | 9.2029 | 8.9303 | 9.9933 | 9.2997 | 9.0788 | 8.1297 | 9.1119 | 8.5989 | 8.6875 | 9.3586 | 6.9470 | 9.5231 | 10.0450 | 8.8709 | 9.2287 | 7.8518 | 9.8127 | 8.3161 | 9.9684 | 7.0200 | 9.0656 | 8.4641 | 9.2247 | 10.3568 | 8.1555 | 9.4958 | 8.5609 | 8.4441 | 8.3472 | 8.9405 | 8.8446 | 9.3201 | 9.6297 | 8.7775 | 9.0680 | 8.0878 | 8.8101 | 8.7726 | 9.2729 | 10.9321 | 11.0070 | 9.8828 | 9.3688 | 8.1453 | 8.9585 | 9.8662 | 8.2470 | 9.2442 | 9.2014 | 8.4704 | 8.6461 | 8.3497 | 8.9950 | 9.7976 | 9.8409 | 8.0504 | 8.7424 | 8.3555 | 8.6042 | 8.5959 | 9.6190 | 10.1597 | 8.3414 | 9.3474 | 8.3507 | 9.8054 | 8.8262 | 10.1276 | 9.0223 | 10.4546 | 8.3054 | 7.8236 | 10.8337 | 9.5080 | 9.4788 | 9.3927 | 8.4003 | 9.2875 | 8.1302 | 11.2650 | 9.7314 | 10.6508 | 8.9532 | 8.3954 | 9.4681 | 9.4958 | 9.4666 | 9.5036 | 9.7567 | 11.3073 | 9.9932 | 9.9207 | 8.6758 | 9.6292 | 9.0422 | 7.5520 | 9.1814 | 6.8809 | 9.6594 | 8.6008 | 8.5979 | 7.2644 | 8.8792 | 9.8360 | 9.9183 | 8.1969 | 9.7329 | 9.7718 | 8.2338 | 8.5896 | 8.5098 | 8.2704 | 9.8404 | 8.1370 | 11.9181 | 7.6586 | 9.5109 | 9.1844 | 8.2154 | 7.5763 | 9.3099 | 8.3623 | 8.8870 | 8.7809 | 8.7308 | 10.21050 |
| TNMD | 4.6488 | 4.2792 | 5.0983 | 5.0612 | 5.4898 | 6.0632 | 5.2203 | 4.8097 | 5.3536 | 5.7317 | 6.4832 | 5.5584 | 5.7346 | 6.1384 | 4.8078 | 5.3155 | 5.0107 | 6.2699 | 5.2936 | 6.1975 | 6.0003 | 5.6974 | 6.0879 | 5.2412 | 5.2831 | 5.6022 | 7.5804 | 5.2450 | 7.4099 | 5.1164 | 5.3450 | 6.5737 | 5.8393 | 5.7641 | 5.1021 | 5.7527 | 6.5480 | 4.8469 | 6.0984 | 5.5746 | 5.4022 | 5.9127 | 6.6194 | 6.4689 | 7.0166 | 6.0898 | 5.3898 | 5.2784 | 5.4546 | 7.0090 | 5.1726 | 5.9127 | 5.8289 | 6.2632 | 6.3032 | 5.7879 | 5.4527 | 5.1069 | 4.8564 | 6.2013 | 7.4471 | 6.6118 | 5.8651 | 5.9651 | 6.2260 | 5.1793 | 4.2545 | 4.9679 | 5.3622 | 6.2299 | 4.9526 | 5.2336 | 6.3451 | 6.0260 | 5.3193 | 5.2288 | 5.9003 | 9.5520 | 5.1964 | 4.8345 | 5.5174 | 6.5899 | 6.6175 | 6.0632 | 4.7926 | 9.4653 | 5.3726 | 5.3860 | 4.8297 | 5.5393 | 5.6936 | 4.6183 | 4.5945 | 5.4498 | 4.7631 | 5.8908 | 6.0927 | 5.3317 | 4.9964 | 5.3869 | 5.3098 | 6.3194 | 5.8079 | 6.9699 | 4.6774 | 7.2004 | 6.1118 | 6.1165 | 5.9517 | 5.8527 | 5.5784 | 6.4032 | 5.2669 | 7.0775 | 6.9366 | 6.6089 | 4.7697 | 5.8098 | 5.7632 | 5.7222 | 4.7897 | 4.9212 | 5.3603 | 8.5567 | 5.1326 | 5.7174 | 5.3317 | 6.1603 | 5.5555 | 7.5947 | 4.8212 | 5.3774 | 5.1250 | 5.0069 | 4.9993 | 5.3774 | 4.8202 | 4.7288 | 5.9136 | 4.2287 | 5.4269 | 5.3393 | 6.0241 | 7.8166 | 5.2993 | 6.1384 | 6.5651 | 6.7251 | 7.3976 | 5.2812 | 5.0850 | 6.6070 | 5.3479 | 5.4260 | 4.6107 | 5.1126 | 5.5831 | 6.2622 | 6.9385 | 5.8279 | 5.4146 | 4.9488 | 4.9117 | 6.2956 | 6.0194 | 5.1812 | 6.3737 | 5.3803 | 5.4527 | 6.0756 | 5.8041 | 4.8917 | 4.9755 | 6.1441 | 4.8650 | 5.5536 | 6.0203 | 5.3536 | 6.2518 | 6.3413 | 5.3184 | 5.6631 | 7.6262 | 5.4746 | 5.2622 | 6.5375 | 5.1755 | 4.7802 | 5.1545 | 6.2480 | 5.7212 | 5.0945 | 5.6984 | 5.1060 | 5.1012 | 5.7031 | 7.2156 | 5.7603 | 4.3449 | 5.3041 | 6.4451 | 5.3679 | 5.5403 | 5.0926 | 5.9203 | 6.3861 | 5.1983 | 5.9317 | 4.6621 | 5.2793 | 5.4812 | 5.5374 | 5.7336 | 5.7593 | 6.4575 | 5.6174 | 5.7060 | 6.0117 | 5.2107 | 5.6993 | 6.0917 | 7.9757 | 6.3337 | 6.0622 | 5.2698 | 6.4594 | 6.1984 | 5.8146 | 5.9698 | 5.6917 | 4.3726 | 6.6585 | 4.9755 | 5.5803 | 5.7136 | 5.0612 | 5.7422 | 5.7841 | 6.0889 | 4.9298 | 5.5212 | 6.0375 | 5.0393 | 7.0842 | 4.9964 | 5.4660 | 5.4546 | 5.2755 | 5.0012 | 5.7765 | 5.2479 | 5.3545 | 6.2203 | 5.8613 | 5.7031 | 5.4041 | 5.4679 | 6.9785 | 5.4193 | 6.3356 | 5.6546 | 5.7603 | 8.3329 | 6.2537 | 5.7603 | 4.9726 | 5.4174 | 5.6317 | 4.7097 | 5.9536 | 6.1337 | 6.4537 | 5.0583 | 6.4489 | 5.4784 | 5.8012 | 5.8593 | 5.4355 | 4.6650 | 5.6908 | 5.8593 | 6.3651 | 5.7117 | 6.8442 | 5.2364 | 5.7698 | 5.3841 | 6.6461 | 5.7717 | 5.8098 | 4.9802 | 6.0279 | 5.9555 | 6.1422 | 6.3851 | 5.3060 | 5.8898 | 5.7336 | 6.4746 | 5.7127 | 6.0298 | 4.8793 | 4.8669 | 5.9232 | 5.1783 | 6.7499 | 5.7451 | 5.5736 | 5.6041 | 6.6508 | 4.4250 | 6.2603 | 5.5641 | 6.5013 | 5.7689 | 5.6089 | 6.0146 | 6.2718 | 6.8775 | 5.1622 | 5.0383 | 5.4498 | 5.8155 | 7.0566 | 7.6995 | 5.3050 | 5.3222 | 4.6783 | 6.2518 | 6.0041 | 6.2213 | 4.7707 | 5.2431 | 6.9570 | 5.6087 | 5.8998 | 5.9391 | 4.9656 | 5.5148 | 6.8062 | 4.8912 | 5.5922 | 5.4497 | 5.7749 | 6.0330 | 6.8114 | 4.4979 | 5.7584 | 4.8159 | 5.7925 | 4.7436 | 5.1421 | 5.0275 | 5.9122 | 5.2753 | 4.8551 | 5.5519 | 5.5499 | 6.3283 | 6.0247 | 4.6641 | 5.9442 | 5.0533 | 5.7904 | 4.6837 | 5.9040 | 7.2233 | 4.9366 | 4.8107 | 5.3186 | 4.9707 | 5.8018 | 4.9274 | 5.5757 | 5.7718 | 5.2763 | 5.7646 | 6.5709 | 5.6965 | 5.8307 | 5.8369 | 5.0017 | 6.0774 | 6.2219 | 5.9401 | 5.7956 | 5.3991 | 4.9945 | 4.6455 | 5.7501 | 6.1848 | 4.8850 | 6.1589 | 5.5561 | 5.4043 | 6.2735 | 5.2453 | 6.5709 | 6.5223 | 5.6118 | 6.7216 | 4.9841 | 5.1576 | 5.9339 | 5.6996 | 5.1545 | 5.7254 | 6.0691 | 5.4384 | 6.3293 | 5.6345 | 6.0753 | 6.5399 | 5.5457 | 4.7766 | 5.0492 | 5.4239 | 6.2787 | 6.1486 | 5.8193 | 4.8386 | 6.0960 | 4.8768 | 5.6335 | 4.9841 | 5.4962 | 5.5963 | 5.0512 | 5.0574 | 5.2443 | 5.0739 | 6.6792 | 6.0743 | 6.1951 | 6.5182 | 5.8400 | 5.9938 | 7.0230 | 5.4384 | 4.0664 | 5.0285 | 5.7243 | 5.9834 | 5.8689 | 5.6273 | 5.6727 | 7.0984 | 5.8049 | 5.6242 | 5.3300 | 6.5358 | 5.7192 | 6.4996 | 5.5953 | 6.4821 | 7.0457 | 4.8912 | 6.2477 | 6.3035 | 6.0371 | 5.2247 | 7.2522 | 5.8162 | 5.8482 | 5.6087 | 6.7856 | 5.6479 | 5.0729 | 5.6345 | 6.1435 | 5.0884 | 5.4291 | 5.3093 | 5.3960 | 5.6655 | 4.8737 | 5.2319 | 6.0960 | 5.4539 | 5.8709 | 5.5488 | 5.9029 | 5.2794 | 6.2312 | 4.8768 | 5.7987 | 6.5863 | 5.6056 | 8.0832 | 5.4373 | 5.4704 | 6.4800 | 6.1837 | 6.0918 | 5.6469 | 6.4160 | 4.8912 | 4.8221 | 5.5086 | 5.5447 | 5.6965 | 5.4404 | 5.8709 | 4.9996 | 6.1435 | 6.8671 | 6.9322 | 7.2305 | 5.9287 | 5.4291 | 5.8833 | 7.5743 | 8.2722 | 5.0905 | 6.5296 | 4.5887 | 3.8692 | 5.5757 | 6.6441 | 5.5189 | 7.0592 | 5.5117 | 5.1101 | 5.1731 | 6.4790 | 5.2938 | 5.9896 | 4.9625 | 4.4091 | 7.6662 | 5.2856 | 5.1214 | 4.7364 | 5.4890 | 4.8148 | 5.8751 | 4.3616 | 6.3190 | 6.8362 | 5.7656 | 5.2536 | 5.9360 | 5.2907 | 5.9009 | 4.7622 | 5.4218 | 5.7047 | 7.0106 | 5.5375 | 5.3568 | 5.4249 | 6.2044 | 4.7353 | 6.7773 | 6.4274 | 5.6861 | 6.9900 | 6.7835 | 5.7501 | 4.8355 | 5.6252 | 5.4239 | 5.5003 | 5.0543 | 5.7161 | 5.2113 | 5.0915 | 7.4494 | 5.8802 | 6.4676 | 7.6022 | 8.3558 | 5.3640 | 5.6324 | 5.5457 | 5.2133 | 5.4859 | 6.4831 | 8.6789 | 6.5058 | 5.5973 | 6.7866 | 6.1414 | 5.1617 | 5.7646 | 5.8038 | 5.9587 | 4.8685 | 5.4280 | 5.3692 | 5.1039 | 5.6128 | 5.9411 | 5.6614 | 5.9174 | 5.3506 | 5.8049 | 5.4188 | 7.4979 | 4.8964 | 5.6645 | 7.4463 | 5.9752 | 6.7649 | 6.2901 | 5.4931 | 6.8909 | 6.1641 | 5.1534 | 5.4301 | 5.1452 | 5.3227 | 5.3950 | 6.6514 | 7.6992 | 5.3516 | 6.0392 | 5.9721 | 6.2064 | 7.7395 | 5.5189 | 6.4614 | 5.5943 | 5.4518 | 5.9380 | 5.5168 | 6.4015 | 5.0265 | 5.8503 | 5.0987 | 5.8658 | 6.0578 | 4.9800 | 6.4810 | 5.3723 | 7.9511 | 6.3964 | 6.8104 | 5.6407 | 6.3272 | 5.2711 | 6.2983 | 5.7316 | 5.2587 | 6.9126 | 4.9965 | 6.2147 | 6.6431 | 5.7759 | 6.6152 | 5.0574 | 4.7766 | 5.4053 | 5.3568 | 5.1813 | 6.6792 | 5.7863 | 6.5585 | 5.2732 | 5.7357 | 5.7057 | 5.9927 | 5.5354 | 6.3386 | 5.3950 | 5.9545 | 6.5378 | 7.8716 | 6.9260 | 6.2209 | 6.0423 | 5.0409 | 5.9535 | 5.5179 | 5.4425 | 4.9305 | 5.1947 | 5.7460 | 5.2298 | 6.1817 | 6.2436 | 6.2033 | 5.9194 | 6.2890 | 5.8689 | 4.7343 | 5.0595 | 5.2753 | 5.8482 | 5.5468 | 7.9191 | 5.3806 | 5.6283 | 5.1121 | 6.4057 | 7.0354 | 5.9545 | 5.7419 | 5.8678 | 5.2381 | 6.0733 | 5.6128 | 5.2092 | 6.0640 | 6.0216 | 6.2498 | 4.9057 | 4.4473 | 6.2168 | 5.2402 | 4.4556 | 7.9336 | 5.5416 | 6.9157 | 7.5929 | 5.3496 | 6.6586 | 6.4790 | 5.4766 | 5.4869 | 5.1472 | 6.0475 | 6.0413 | 5.4683 | 5.8864 | 6.1094 | 5.3227 | 4.9470 | 5.6634 | 4.7704 | 5.3176 | 5.7233 | 5.0450 | 5.0801 | 5.5509 | 7.5155 | 5.6438 | 4.7777 | 5.1462 | 4.6146 | 6.2673 | 5.6004 | 6.5368 | 5.7285 | 5.6015 | 5.6386 | 5.0894 | 5.2288 | 5.7367 | 5.5375 | 5.4652 | 5.4373 | 6.0454 | 6.0237 | 5.6686 | 5.7956 | 5.2340 | 5.7543 | 6.6060 | 5.7821 | 5.9514 | 4.9098 | 5.5478 | 5.7254 | 5.9009 | 4.9325 | 5.2598 | 5.1318 | 5.7212 | 6.6235 | 5.4838 | 5.7615 | 5.2814 | 5.4311 | 5.7243 | 4.6300 | 4.8303 | 4.8603 | 4.9728 | 6.1362 | 5.2670 | 6.2591 | 5.3269 | 6.2993 | 4.5299 | 5.5437 | 8.3868 | 5.6903 | 5.8307 | 4.7777 | 5.6149 | 6.5192 | 6.6421 | 5.3155 | 4.8592 | 5.0409 | 4.7673 | 6.9115 | 7.5289 | 5.1999 | 6.0454 | 5.9329 | 4.7570 | 5.9917 | 4.8427 | 6.0650 | 4.9480 | 5.3372 | 5.3516 | 6.0640 | 6.0939 | 4.9263 | 4.7622 | 5.8565 | 5.3486 | 6.3530 | 5.4776 | 5.7749 | 6.6411 | 4.9945 | 6.9219 | 5.4900 | 4.7735 | 5.2866 | 6.0124 | 5.5602 | 5.4363 | 4.9170 | 6.5440 | 5.2082 | 5.0471 | 5.1390 | 5.5592 | 5.9040 | 10.7490 | 7.4184 | 5.1854 | 5.7243 | 5.5437 | 4.7446 | 6.0402 | 5.5271 | 5.1782 | 5.2061 | 5.2918 | 6.9435 | 5.5416 | 4.8458 | 4.7519 | 5.0347 | 5.4208 | 4.8850 | 5.1989 | 6.7949 | 4.7188 | 5.8627 | 5.1132 | 6.0330 | 6.6380 | 6.0330 | 5.4714 | 4.4731 | 5.6087 | 6.0629 | 5.2825 | 6.4470 | 5.4012 | 4.9470 | 5.5788 | 5.3042 | 5.6170 | 5.4993 | 5.3547 | 4.8045 | 5.4704 | 5.0956 | 5.4600 | 5.8237 | 4.2575 | 5.6699 | 5.1103 | 5.6048 | 6.1665 | 4.2162 | 5.3571 | 7.8668 | 5.1299 | 5.5718 | 5.9961 | 4.7624 | 5.9455 | 5.0205 | 6.0199 | 4.5828 | 7.6800 | 5.9125 | 4.1522 | 5.0628 | 5.1206 | 5.7865 | 5.2383 | 5.1371 | 5.9238 | 5.2538 | 6.5939 | 5.0040 | 5.6802 | 5.2714 | 5.1919 | 5.6513 | 5.5739 | 5.0587 | 5.1784 | 5.1650 | 5.4902 | 4.8522 | 5.3199 | 5.3044 | 5.4562 | 6.2759 | 5.0866 | 6.1995 | 5.9920 | 5.3798 | 5.0649 | 5.4603 | 5.0556 | 4.5033 | 4.0872 | 6.1283 | 6.1654 | 4.6550 | 5.2796 | 6.6558 | 7.0151 | 4.9224 | 6.0839 | 4.5600 | 5.5243 | 5.0669 | 5.0380 | 5.4634 | 5.3777 | 5.8887 | 5.7390 | 4.3019 | 5.9982 | 5.3911 | 6.6713 | 5.2868 | 5.9734 | 3.6546 | 8.0392 | 5.2621 | 4.6664 | 5.5016 | 4.5900 | 5.6657 | 4.5838 | 6.2656 | 6.4865 | 6.7539 | 4.4764 | 4.8718 | 4.1822 | 4.2710 | 4.6571 | 4.9338 | 4.4207 | 6.0085 | 4.2132 | 4.9049 | 5.4334 | 5.0752 | 5.0267 | 6.1726 | 6.1210 | 4.8388 | 4.0160 | 5.9589 | 4.2452 | 4.9296 | 4.7294 | 4.4403 | 5.7236 | 4.2193 | 5.88410 |
| DPM1 | 12.2580 | 12.8160 | 12.7220 | 12.9750 | 12.5100 | 12.2510 | 13.2410 | 13.0880 | 12.4680 | 12.7430 | 12.6220 | 12.4200 | 13.1130 | 12.5510 | 13.6830 | 13.3890 | 12.6320 | 12.7200 | 11.9500 | 14.6470 | 12.1190 | 13.2860 | 12.4690 | 13.5980 | 12.4700 | 12.6610 | 13.7830 | 12.8110 | 12.7600 | 13.1550 | 12.8730 | 12.8640 | 13.0790 | 12.6920 | 13.1000 | 12.4800 | 12.9640 | 12.2910 | 12.0860 | 12.9590 | 11.6340 | 12.3470 | 11.8070 | 12.5570 | 12.4650 | 11.6260 | 13.9020 | 12.2310 | 12.4510 | 13.5670 | 12.3920 | 12.0980 | 13.3310 | 13.7710 | 12.9090 | 12.8360 | 13.6220 | 12.5050 | 13.7380 | 12.9950 | 12.4020 | 13.9050 | 12.2600 | 12.8620 | 12.7170 | 14.1800 | 12.6530 | 12.7150 | 13.0000 | 12.7470 | 12.3300 | 12.7700 | 13.4490 | 12.2770 | 12.6360 | 12.0950 | 12.1110 | 13.1380 | 13.2730 | 14.3070 | 13.0200 | 12.2040 | 12.2650 | 12.2200 | 12.8430 | 12.0220 | 12.3010 | 12.4390 | 13.7420 | 12.5110 | 12.3310 | 12.6820 | 14.6380 | 12.4500 | 13.0390 | 12.9480 | 12.5080 | 12.9480 | 12.5550 | 12.6370 | 13.2920 | 13.3230 | 13.3460 | 13.4290 | 12.2620 | 13.0980 | 13.5910 | 13.3470 | 13.0990 | 12.5840 | 13.0120 | 12.6920 | 13.6540 | 13.5880 | 12.3950 | 12.2360 | 12.7680 | 12.4060 | 11.8890 | 12.7600 | 13.0640 | 12.8630 | 13.7050 | 13.4460 | 14.4310 | 12.7920 | 13.4650 | 12.4000 | 12.6850 | 12.9660 | 12.7540 | 13.4830 | 12.8430 | 13.0630 | 11.9360 | 12.3580 | 12.8380 | 13.1680 | 14.1120 | 13.7650 | 13.0140 | 12.6670 | 12.5790 | 12.9020 | 13.4780 | 13.2230 | 12.0950 | 12.7730 | 13.4700 | 13.3160 | 12.4690 | 12.3210 | 12.6720 | 12.1070 | 13.9110 | 13.2100 | 11.7510 | 12.6800 | 12.2920 | 12.6090 | 13.4330 | 13.5410 | 13.0840 | 12.9860 | 12.4440 | 13.2170 | 12.0470 | 12.8930 | 12.2210 | 12.9380 | 12.1020 | 12.2380 | 12.6140 | 12.2820 | 13.2240 | 13.1480 | 12.7590 | 13.8930 | 13.2830 | 12.5410 | 12.6500 | 13.3050 | 12.9170 | 12.8940 | 13.3510 | 12.4400 | 12.2030 | 13.0520 | 12.4440 | 13.4650 | 12.3150 | 12.7750 | 13.2740 | 11.8200 | 12.8050 | 12.6370 | 12.1280 | 13.8160 | 12.3010 | 12.9750 | 12.9800 | 12.4990 | 13.1440 | 12.7970 | 12.2830 | 13.3730 | 12.0080 | 12.9540 | 12.6220 | 13.5090 | 12.4670 | 12.6170 | 12.5270 | 13.0210 | 12.7990 | 13.0570 | 13.1570 | 12.7300 | 12.0760 | 13.5070 | 14.4750 | 12.1150 | 12.3410 | 12.9210 | 13.4150 | 12.0360 | 13.4810 | 13.0650 | 12.3840 | 13.5770 | 13.4530 | 13.2940 | 12.3220 | 12.2080 | 12.9480 | 13.6830 | 13.0260 | 12.7190 | 12.5380 | 12.7400 | 13.9950 | 13.1910 | 12.0630 | 13.0170 | 12.3770 | 12.3280 | 12.2400 | 14.5130 | 13.4780 | 13.4890 | 12.7990 | 12.8640 | 12.7730 | 12.0130 | 13.4710 | 12.5610 | 13.3360 | 13.8670 | 13.2070 | 12.5400 | 12.3470 | 12.6210 | 13.1080 | 11.6110 | 12.0330 | 13.3960 | 12.5940 | 13.8950 | 12.7570 | 13.2360 | 12.6310 | 13.0800 | 12.4080 | 12.6190 | 12.9340 | 12.3430 | 12.6850 | 12.8720 | 12.2500 | 12.4880 | 13.4880 | 11.8420 | 12.6610 | 14.3620 | 12.7440 | 11.9080 | 12.0780 | 13.2480 | 13.2260 | 13.6920 | 12.6270 | 12.9770 | 12.4610 | 11.5310 | 13.5290 | 13.0120 | 11.7760 | 12.6740 | 13.1570 | 12.4710 | 13.7610 | 12.5130 | 12.4960 | 12.6140 | 13.0180 | 13.6790 | 12.8940 | 12.4890 | 13.7120 | 12.7520 | 12.9330 | 13.0980 | 12.8270 | 12.8120 | 13.1920 | 12.8100 | 12.1270 | 13.2080 | 12.3300 | 12.2830 | 12.4420 | 12.8820 | 12.5730 | 13.2960 | 11.4670 | 12.3060 | 12.2790 | 13.0510 | 12.3640 | 11.9140 | 13.8160 | 13.3580 | 12.2740 | 12.3690 | 12.8940 | 13.9950 | 12.6790 | 12.6430 | 13.3150 | 13.0360 | 13.3640 | 12.1790 | 12.9240 | 13.4190 | 13.8490 | 12.0730 | 12.1240 | 13.4820 | 11.8530 | 13.8310 | 13.9040 | 12.4420 | 13.1770 | 13.0770 | 12.4100 | 13.0810 | 14.0910 | 14.0710 | 12.5270 | 12.7500 | 12.5850 | 12.4850 | 13.0170 | 12.5520 | 13.7210 | 13.9750 | 12.8720 | 13.6620 | 12.2100 | 13.4890 | 12.4890 | 12.2390 | 12.3670 | 12.3390 | 12.3980 | 12.6440 | 12.3490 | 11.9540 | 13.3050 | 13.5380 | 13.6300 | 12.8160 | 13.1660 | 12.6380 | 12.6660 | 13.1830 | 13.9180 | 12.9860 | 12.9660 | 12.7170 | 12.3740 | 13.1700 | 13.4840 | 12.2090 | 12.8870 | 12.9870 | 12.4060 | 12.4290 | 13.4960 | 12.4510 | 13.2590 | 12.2770 | 12.7540 | 12.7260 | 13.1950 | 12.6650 | 13.0820 | 12.5390 | 13.3160 | 13.0400 | 13.0850 | 12.1240 | 13.6180 | 13.5090 | 13.6010 | 14.0170 | 13.4580 | 13.0520 | 12.5060 | 12.9950 | 12.9550 | 12.5910 | 12.6240 | 12.0700 | 12.6020 | 12.8470 | 12.6500 | 14.2470 | 12.6390 | 12.8540 | 12.3200 | 13.2080 | 13.2090 | 12.8770 | 14.9030 | 12.6480 | 12.9200 | 12.3450 | 12.2290 | 13.1020 | 12.7080 | 12.8170 | 13.4390 | 13.6430 | 13.0080 | 12.7860 | 12.7560 | 13.2350 | 12.7080 | 12.0620 | 13.2770 | 12.9920 | 12.3650 | 12.3200 | 12.4360 | 12.9770 | 12.4460 | 13.6930 | 12.1310 | 12.9120 | 12.9160 | 12.4100 | 12.5380 | 12.6140 | 13.0010 | 9.9535 | 13.7150 | 13.4050 | 12.2570 | 12.0150 | 13.2210 | 13.9250 | 13.0420 | 12.4890 | 12.7950 | 12.4010 | 12.3760 | 11.9440 | 11.9510 | 12.4300 | 13.6490 | 12.5390 | 12.7990 | 12.9840 | 13.2540 | 12.3250 | 13.3890 | 13.2900 | 12.0570 | 12.4440 | 12.2230 | 13.0070 | 13.1490 | 13.0550 | 12.7680 | 13.6220 | 13.5320 | 12.5580 | 12.8100 | 13.3400 | 12.4000 | 13.1670 | 13.7330 | 13.4660 | 13.1110 | 12.7450 | 13.4140 | 12.2510 | 12.9710 | 12.6120 | 12.8750 | 12.5640 | 12.6060 | 12.6270 | 12.0770 | 12.9830 | 12.5720 | 13.1050 | 13.7550 | 12.5010 | 12.7580 | 12.2580 | 14.3780 | 13.4760 | 13.3280 | 12.5740 | 12.5850 | 12.7630 | 13.6500 | 12.4260 | 12.7140 | 12.8200 | 12.4560 | 12.8040 | 12.9690 | 13.3370 | 11.9880 | 12.8280 | 12.3050 | 12.7240 | 13.0550 | 13.0950 | 13.0210 | 13.7080 | 12.7240 | 13.3990 | 12.7610 | 13.1830 | 12.9540 | 13.0040 | 12.5890 | 12.6470 | 13.9290 | 12.9100 | 12.7960 | 12.5070 | 12.4940 | 12.3670 | 13.2650 | 12.4920 | 12.1810 | 11.7000 | 13.0030 | 12.8470 | 11.8760 | 12.4850 | 12.6490 | 12.9030 | 13.5180 | 12.7840 | 12.7740 | 12.8780 | 13.0470 | 13.3210 | 12.4160 | 12.7720 | 12.9700 | 12.0090 | 12.2800 | 12.6840 | 13.5740 | 12.9600 | 13.2010 | 13.5680 | 12.8980 | 13.1420 | 11.9290 | 12.0980 | 13.5490 | 12.6100 | 13.0210 | 13.2120 | 13.3580 | 12.5490 | 13.1170 | 12.3410 | 12.5570 | 12.1660 | 12.8300 | 11.7820 | 12.7530 | 12.8290 | 12.8280 | 12.1540 | 12.3930 | 12.5620 | 13.0830 | 12.6770 | 13.8070 | 13.9190 | 12.4710 | 12.2130 | 12.7950 | 13.1940 | 12.9630 | 13.0210 | 12.7290 | 12.4520 | 12.6300 | 13.2830 | 11.7360 | 13.9080 | 13.0790 | 12.4960 | 13.0400 | 12.9690 | 12.0870 | 12.4100 | 12.6170 | 13.3120 | 12.2010 | 13.1150 | 12.5320 | 12.8530 | 12.5530 | 12.9480 | 12.6880 | 13.4460 | 13.7520 | 13.0010 | 13.5340 | 11.9480 | 12.6080 | 12.7020 | 12.5350 | 12.6770 | 12.3690 | 12.2650 | 12.5770 | 12.8270 | 12.5390 | 12.1740 | 14.1990 | 12.9930 | 12.2740 | 12.5800 | 12.6700 | 11.8380 | 12.4150 | 12.1400 | 13.2570 | 13.7960 | 11.9530 | 12.2960 | 12.5070 | 12.9040 | 13.6510 | 12.6530 | 13.4010 | 12.5110 | 13.2420 | 12.4590 | 12.8580 | 12.4800 | 13.8760 | 12.6050 | 12.5470 | 13.5110 | 12.4310 | 12.8950 | 13.8960 | 12.0910 | 14.2380 | 13.1760 | 12.1270 | 12.8560 | 12.4390 | 12.2180 | 12.3370 | 11.9900 | 13.1080 | 13.0400 | 12.7630 | 12.6460 | 12.5310 | 12.6740 | 12.4200 | 13.2670 | 12.2820 | 12.2420 | 12.1000 | 13.7260 | 12.9970 | 12.6340 | 13.3520 | 13.0130 | 15.2450 | 13.4220 | 11.9060 | 12.7820 | 11.8350 | 12.8940 | 12.6100 | 13.2230 | 12.4010 | 13.7640 | 13.7900 | 12.1280 | 12.6150 | 13.2160 | 13.3860 | 14.3990 | 12.0550 | 13.8990 | 13.5850 | 13.2190 | 13.4300 | 12.5510 | 12.0460 | 12.8830 | 12.9540 | 13.0980 | 12.4710 | 12.7570 | 12.9560 | 14.1500 | 13.4810 | 13.0170 | 12.0580 | 13.0600 | 13.0010 | 11.8330 | 12.2940 | 12.7140 | 12.7930 | 13.6630 | 13.1960 | 12.2980 | 12.9990 | 12.3910 | 12.2210 | 13.4810 | 12.1950 | 12.7970 | 12.5990 | 12.1090 | 12.5860 | 12.1860 | 12.9510 | 11.8000 | 12.9730 | 12.1340 | 12.9140 | 11.8150 | 13.2790 | 13.2290 | 13.1480 | 12.6810 | 12.2890 | 12.4400 | 11.9510 | 12.8910 | 11.7230 | 12.0770 | 13.4920 | 12.7410 | 13.5520 | 12.4390 | 12.4590 | 12.3910 | 13.4180 | 13.7240 | 12.3730 | 13.8110 | 13.2030 | 12.1550 | 12.2590 | 12.7570 | 13.2190 | 13.0360 | 14.4760 | 13.0650 | 12.7350 | 13.3780 | 13.0690 | 12.1530 | 12.6920 | 12.1200 | 12.8570 | 13.1760 | 11.6360 | 14.1570 | 14.4070 | 13.0020 | 12.7390 | 12.2370 | 12.1710 | 11.8170 | 12.5780 | 13.5360 | 13.0340 | 13.4050 | 11.9690 | 12.2320 | 12.5880 | 12.1100 | 12.8590 | 12.4730 | 13.5870 | 12.9810 | 12.1730 | 12.1220 | 12.0730 | 12.2560 | 11.9250 | 13.8840 | 12.8820 | 12.9760 | 12.5040 | 12.4600 | 12.6780 | 13.0500 | 12.4190 | 12.4270 | 12.5220 | 12.5140 | 13.3460 | 13.0710 | 13.8820 | 12.9800 | 12.4000 | 12.4190 | 12.7290 | 12.4540 | 11.7010 | 13.7250 | 13.1190 | 13.6990 | 13.5140 | 13.0760 | 13.0290 | 11.7570 | 12.6280 | 11.8740 | 12.6710 | 13.9050 | 12.6210 | 12.2800 | 13.5320 | 12.4540 | 11.5610 | 12.5090 | 12.4480 | 12.2330 | 13.6200 | 12.0440 | 13.6470 | 13.6620 | 12.1210 | 12.0460 | 13.2980 | 14.3260 | 13.3560 | 13.3790 | 12.6460 | 12.9410 | 12.8910 | 11.8190 | 12.4453 | 13.0688 | 13.6361 | 12.0348 | 9.0392 | 12.2096 | 13.5886 | 11.8846 | 12.7722 | 12.7086 | 13.0032 | 11.8608 | 12.3655 | 13.8005 | 12.1469 | 12.7200 | 11.7535 | 13.5705 | 12.3446 | 11.9910 | 12.4738 | 14.4430 | 13.4061 | 12.0481 | 12.7950 | 13.1543 | 14.0695 | 12.4824 | 12.3123 | 12.4510 | 13.5696 | 12.6686 | 13.5610 | 12.6734 | 12.9091 | 12.1155 | 12.3759 | 12.4852 | 12.0253 | 13.5924 | 12.4368 | 9.0877 | 12.4833 | 13.1999 | 12.6848 | 12.6820 | 14.6663 | 12.2125 | 13.4907 | 11.7658 | 12.6924 | 12.6021 | 12.3854 | 11.9093 | 12.4710 | 12.6677 | 12.3693 | 12.8701 | 12.2590 | 12.0490 | 13.5468 | 12.7266 | 13.6209 | 12.0994 | 13.6637 | 11.7734 | 12.2324 | 14.2016 | 13.6295 | 12.1469 | 11.9502 | 11.8903 | 13.6580 | 12.9728 | 12.0186 | 13.2313 | 14.7984 | 12.5898 | 12.9005 | 12.9965 | 13.0764 | 13.9925 | 12.2020 | 12.7352 | 12.3740 | 12.1136 | 12.6544 | 12.7200 | 12.5023 | 12.3626 | 12.1488 | 13.3482 | 12.0918 | 12.6772 | 12.7057 | 12.9338 | 12.4178 | 11.8000 | 13.6076 | 14.0771 | 13.0507 | 12.4510 | 12.3018 | 12.4311 | 13.1799 | 12.2476 | 12.1193 | 11.8960 | 12.86150 |
| SCYL3 | 9.9888 | 9.1309 | 8.7602 | 8.7112 | 9.0070 | 9.1536 | 9.4303 | 8.9822 | 9.1918 | 9.6543 | 10.0240 | 9.0751 | 9.5598 | 8.9032 | 9.8458 | 9.1004 | 9.6791 | 8.7184 | 8.5140 | 9.0307 | 9.9165 | 9.8148 | 10.2560 | 9.0963 | 8.8500 | 9.5748 | 10.0600 | 8.6079 | 9.9578 | 9.3998 | 9.6099 | 9.3595 | 8.2935 | 9.5397 | 9.2986 | 9.3931 | 9.0586 | 8.6131 | 9.0797 | 9.8727 | 9.0890 | 8.5997 | 8.6833 | 10.5170 | 10.1990 | 9.5836 | 9.5748 | 7.9998 | 9.5067 | 9.7653 | 8.9574 | 9.6161 | 8.7452 | 9.2558 | 9.2516 | 9.2300 | 9.8732 | 9.2831 | 9.5665 | 8.7958 | 9.2387 | 10.0800 | 8.8252 | 9.3358 | 10.4580 | 9.3859 | 9.0452 | 9.3410 | 9.0524 | 8.6828 | 10.6660 | 8.6399 | 11.1620 | 9.5887 | 9.1396 | 9.6502 | 8.6322 | 8.6028 | 9.2677 | 9.1004 | 8.4087 | 9.2109 | 10.3120 | 9.7689 | 9.3895 | 8.6311 | 9.4845 | 9.3482 | 8.7716 | 9.7756 | 9.7839 | 9.9837 | 8.6260 | 9.1882 | 9.0674 | 10.0710 | 10.1420 | 9.2919 | 8.9109 | 9.9573 | 9.4437 | 9.3089 | 8.4892 | 9.2315 | 8.9497 | 9.5634 | 9.1654 | 8.1815 | 10.1530 | 8.8918 | 10.2160 | 9.4168 | 9.2207 | 9.2212 | 8.7659 | 10.2660 | 8.6363 | 9.3513 | 10.7860 | 8.9202 | 9.5371 | 8.6936 | 8.7819 | 9.4256 | 9.1510 | 8.5253 | 9.0018 | 8.7648 | 9.0849 | 8.0602 | 9.2377 | 9.7575 | 9.1081 | 9.4385 | 8.6575 | 8.6441 | 8.0958 | 8.8185 | 10.4090 | 9.2067 | 9.8112 | 9.7281 | 9.2769 | 9.0890 | 9.7297 | 8.9842 | 8.8913 | 9.3508 | 9.7550 | 8.7365 | 9.4679 | 8.0241 | 9.1200 | 9.2253 | 9.1081 | 9.2227 | 8.9801 | 8.6998 | 8.3911 | 8.8092 | 7.8496 | 9.6920 | 8.7380 | 9.5335 | 8.2832 | 8.9651 | 9.7338 | 9.1536 | 9.1546 | 8.8789 | 9.0643 | 8.7762 | 10.2240 | 9.1701 | 9.6089 | 9.6956 | 9.3332 | 9.0674 | 9.6930 | 9.8185 | 8.9476 | 8.6946 | 9.1087 | 9.5268 | 8.8382 | 7.6132 | 8.4009 | 8.4298 | 8.7158 | 9.4783 | 8.7483 | 9.2935 | 8.6601 | 8.8903 | 9.2769 | 9.8040 | 9.7787 | 9.7384 | 9.4127 | 9.1923 | 8.9311 | 9.3621 | 10.1840 | 8.8206 | 10.1840 | 9.3229 | 9.2439 | 8.8418 | 8.2889 | 9.5748 | 8.9047 | 9.3250 | 9.3203 | 9.0957 | 8.7266 | 8.5940 | 8.3111 | 8.8191 | 9.2114 | 8.5971 | 8.8454 | 9.5129 | 9.4783 | 8.8397 | 8.9466 | 8.7070 | 8.8201 | 9.7890 | 8.3028 | 9.7183 | 9.1298 | 10.1300 | 8.5733 | 9.3693 | 8.9218 | 8.3271 | 9.1587 | 9.5929 | 9.5165 | 8.4716 | 9.8556 | 9.6595 | 8.2713 | 9.9950 | 9.0059 | 9.2336 | 8.9884 | 9.2682 | 9.3601 | 8.9429 | 8.9951 | 8.1242 | 8.8438 | 9.2093 | 9.8851 | 9.5428 | 9.4834 | 9.0927 | 9.5960 | 9.2547 | 8.7870 | 9.5299 | 8.5883 | 9.4478 | 9.3456 | 9.7777 | 9.6522 | 9.1887 | 10.5470 | 9.3900 | 8.0726 | 9.0452 | 8.9244 | 8.7731 | 9.7224 | 9.9919 | 8.9559 | 9.8190 | 10.0910 | 8.7525 | 9.7612 | 9.5820 | 9.2248 | 9.4576 | 9.4106 | 9.4008 | 9.1995 | 9.6595 | 10.3270 | 9.2707 | 8.7747 | 8.9104 | 8.6074 | 9.1293 | 9.1345 | 9.1515 | 9.2052 | 9.2439 | 8.9471 | 10.1060 | 8.6296 | 9.9795 | 9.6073 | 9.7049 | 9.2733 | 9.8071 | 9.7188 | 9.2279 | 8.9042 | 9.1825 | 9.0297 | 8.8118 | 8.6270 | 10.4340 | 8.3947 | 9.0338 | 9.4659 | 8.7540 | 9.1871 | 8.7530 | 10.3940 | 9.0415 | 9.1892 | 9.3327 | 8.9249 | 9.0658 | 9.2207 | 9.0674 | 9.6698 | 8.7881 | 9.1773 | 9.1257 | 9.2976 | 8.9143 | 7.9755 | 9.8433 | 8.9172 | 8.9359 | 8.9458 | 9.8206 | 9.3016 | 9.5631 | 8.4887 | 9.5238 | 9.3183 | 9.5130 | 9.0480 | 9.0775 | 8.7423 | 9.2839 | 8.8170 | 8.8563 | 9.2898 | 9.8501 | 9.1168 | 9.5788 | 9.0598 | 9.4314 | 8.9615 | 9.6349 | 8.9802 | 8.8593 | 9.0047 | 9.5464 | 8.7904 | 9.6830 | 8.8386 | 9.7322 | 9.3075 | 9.4903 | 10.1620 | 8.6361 | 8.6971 | 9.2190 | 9.2721 | 8.8838 | 8.8140 | 9.5316 | 8.9428 | 9.2878 | 9.9583 | 9.2928 | 9.3458 | 8.9576 | 9.0863 | 9.5749 | 9.3340 | 9.1001 | 8.7668 | 9.9386 | 9.1207 | 9.5051 | 9.1306 | 9.5592 | 9.3567 | 9.5385 | 10.1400 | 8.6312 | 9.9455 | 9.1011 | 9.3154 | 9.2220 | 8.8651 | 9.0401 | 10.0790 | 9.0539 | 9.7833 | 9.7656 | 9.3793 | 8.7570 | 11.1860 | 9.7086 | 9.8590 | 9.9681 | 9.1463 | 9.8629 | 9.7626 | 9.3911 | 9.1620 | 8.7973 | 8.9693 | 9.7744 | 8.5388 | 8.7462 | 10.4580 | 9.2613 | 9.3930 | 9.6673 | 8.5417 | 10.0440 | 9.3783 | 8.6548 | 9.0136 | 9.2063 | 9.7391 | 9.1325 | 9.9003 | 9.4825 | 9.1414 | 9.1522 | 8.8927 | 9.2652 | 9.1876 | 9.9622 | 9.7253 | 9.3999 | 9.6014 | 10.2840 | 8.5299 | 9.2937 | 9.3763 | 9.6457 | 8.7521 | 8.9025 | 8.7963 | 10.0620 | 9.6093 | 8.8907 | 9.3537 | 9.2878 | 8.5830 | 9.8000 | 8.7639 | 8.6843 | 9.1532 | 8.5624 | 9.7744 | 9.1030 | 9.3399 | 8.1928 | 8.5083 | 9.5218 | 8.9330 | 9.2888 | 8.4552 | 9.8118 | 8.4906 | 9.2259 | 9.1925 | 9.0962 | 9.4569 | 9.4127 | 10.5630 | 8.7187 | 9.6260 | 8.4238 | 9.2092 | 9.6398 | 8.8327 | 8.3147 | 8.8209 | 9.3989 | 9.6801 | 9.3793 | 9.4756 | 8.9988 | 8.5673 | 8.9969 | 10.0320 | 9.8482 | 9.9229 | 9.2908 | 8.9507 | 9.0893 | 8.9929 | 9.1355 | 9.3999 | 8.5014 | 9.9180 | 9.8374 | 9.4402 | 9.1011 | 9.2318 | 9.0883 | 9.2456 | 8.2773 | 8.5162 | 8.5742 | 8.5211 | 9.0549 | 9.1315 | 8.6990 | 8.8710 | 8.9389 | 8.3933 | 8.2036 | 9.7646 | 9.3134 | 8.4719 | 9.4422 | 9.5238 | 9.4117 | 8.5791 | 8.9438 | 9.5483 | 9.2731 | 8.2252 | 8.4198 | 8.9920 | 9.1384 | 9.8659 | 8.9074 | 9.1168 | 8.8917 | 8.9222 | 9.6417 | 9.5857 | 9.0667 | 8.7108 | 9.3911 | 10.1380 | 10.2460 | 9.1945 | 8.9733 | 9.0450 | 9.0775 | 9.1207 | 10.1620 | 8.9517 | 9.0971 | 8.4798 | 8.6813 | 8.3835 | 8.2242 | 8.1328 | 9.1935 | 8.6892 | 10.2660 | 10.5010 | 9.4530 | 9.3793 | 9.7499 | 9.6054 | 9.2249 | 8.8229 | 9.2122 | 9.5926 | 9.0578 | 8.9949 | 8.6676 | 8.7364 | 9.7833 | 8.9988 | 9.5523 | 9.4412 | 9.9494 | 8.7668 | 8.8976 | 9.4589 | 8.9251 | 9.2819 | 9.0087 | 9.3576 | 9.1443 | 9.4441 | 8.6282 | 8.5467 | 8.9723 | 8.5476 | 8.9743 | 9.4658 | 9.5238 | 9.5474 | 10.0170 | 9.3616 | 8.7226 | 9.5641 | 9.9533 | 8.8229 | 9.6319 | 9.0696 | 9.7666 | 9.3154 | 8.7364 | 8.7334 | 9.4618 | 8.6096 | 8.7875 | 9.2711 | 8.4896 | 8.9418 | 10.2550 | 10.4060 | 10.8110 | 8.4071 | 9.4559 | 8.7069 | 10.2090 | 8.2930 | 8.8189 | 9.0804 | 9.0844 | 9.0195 | 10.6190 | 8.6066 | 9.4215 | 9.9406 | 8.8828 | 9.2702 | 9.9799 | 9.6142 | 8.2301 | 8.8946 | 9.8973 | 9.5847 | 8.4533 | 9.1777 | 10.2480 | 9.6142 | 9.0362 | 9.0332 | 8.9349 | 9.1728 | 8.9389 | 8.6990 | 10.1590 | 8.2675 | 8.8760 | 9.2407 | 9.2240 | 9.0057 | 9.5769 | 8.7030 | 9.0991 | 8.6204 | 9.4845 | 8.9035 | 8.9998 | 8.9222 | 9.5041 | 8.7600 | 8.9330 | 9.3085 | 8.8484 | 8.8140 | 9.3006 | 10.2560 | 9.3783 | 8.2478 | 9.2151 | 9.1748 | 9.6378 | 7.9539 | 8.5693 | 9.7862 | 9.7597 | 9.1217 | 9.0205 | 9.4903 | 8.5014 | 8.7334 | 8.4601 | 9.2004 | 8.3963 | 9.5749 | 9.9357 | 9.7273 | 9.7046 | 9.2810 | 9.4196 | 8.9182 | 9.2053 | 9.1266 | 9.5985 | 9.0912 | 9.1355 | 8.6784 | 8.6499 | 8.4425 | 9.6054 | 8.7993 | 9.5975 | 8.2488 | 9.4972 | 8.9861 | 9.4835 | 9.5592 | 8.8003 | 8.6450 | 9.7931 | 9.5749 | 10.2400 | 8.4680 | 11.9280 | 9.2063 | 9.3793 | 10.2690 | 8.9929 | 8.7492 | 8.7895 | 9.1129 | 9.3812 | 8.8701 | 9.6309 | 9.3370 | 8.4366 | 9.3527 | 8.6066 | 9.2220 | 8.9045 | 9.9946 | 9.2878 | 8.7403 | 7.9401 | 9.1207 | 8.8209 | 9.7980 | 10.0020 | 9.2790 | 9.0686 | 10.2620 | 9.0883 | 8.7285 | 8.4316 | 9.1807 | 9.6614 | 9.9819 | 8.7206 | 10.1160 | 9.4628 | 9.4333 | 8.8838 | 9.4363 | 9.9062 | 10.4180 | 9.0362 | 8.1466 | 9.3753 | 8.9025 | 9.8315 | 10.2930 | 8.3786 | 9.1374 | 9.6152 | 9.6634 | 9.5031 | 8.5417 | 9.9760 | 8.2852 | 10.4100 | 9.6929 | 9.2279 | 8.7354 | 9.6840 | 9.0735 | 9.9809 | 8.7786 | 8.6056 | 11.3480 | 9.0273 | 8.6803 | 10.3650 | 8.6125 | 9.9484 | 8.9723 | 8.8298 | 9.1571 | 9.7725 | 9.2475 | 9.1256 | 9.2475 | 9.0637 | 8.9458 | 9.3016 | 8.5073 | 8.8327 | 9.2397 | 8.7895 | 8.9782 | 9.3282 | 8.9880 | 10.2640 | 8.9635 | 8.3923 | 9.2072 | 8.9055 | 9.9504 | 8.4611 | 9.5012 | 9.6162 | 9.7410 | 8.5958 | 8.9782 | 9.5749 | 8.6145 | 9.1158 | 9.2564 | 9.3881 | 10.1480 | 9.6221 | 8.7944 | 9.2977 | 8.9153 | 8.9222 | 9.8541 | 9.4559 | 9.5159 | 9.1129 | 9.6771 | 8.5840 | 9.5995 | 9.9416 | 9.1994 | 9.2230 | 10.2580 | 9.1443 | 10.5020 | 9.2574 | 9.5936 | 9.8845 | 8.4454 | 8.8130 | 9.0991 | 9.8816 | 8.5712 | 9.1443 | 10.6420 | 8.6774 | 10.1240 | 9.6044 | 8.3333 | 8.9556 | 8.8917 | 9.8570 | 9.6732 | 9.5887 | 9.6260 | 9.5405 | 8.9920 | 9.1227 | 9.9101 | 9.0283 | 8.6341 | 8.7462 | 8.9595 | 9.1561 | 9.4500 | 8.6577 | 9.4884 | 9.5090 | 9.9386 | 9.7380 | 8.1574 | 9.0352 | 10.4979 | 9.3016 | 9.3360 | 9.2210 | 9.3055 | 9.6633 | 9.1915 | 9.6574 | 10.2305 | 9.5552 | 9.7695 | 8.6046 | 8.1652 | 9.6270 | 8.7432 | 8.7944 | 9.1355 | 9.1443 | 9.5306 | 8.8917 | 9.3104 | 8.6980 | 8.3992 | 8.7491 | 8.9919 | 8.9231 | 9.5945 | 8.7393 | 8.9703 | 8.8917 | 9.4117 | 9.3242 | 9.4087 | 9.7970 | 9.0902 | 9.0549 | 9.3045 | 8.9674 | 8.8779 | 9.9366 | 8.9251 | 8.7796 | 10.3406 | 9.6859 | 8.9772 | 9.6604 | 8.8710 | 8.9546 | 10.1077 | 8.5014 | 9.0735 | 9.3419 | 9.6594 | 10.2315 | 8.9526 | 9.2141 | 10.0546 | 9.2642 | 9.9936 | 9.1591 | 8.8455 | 8.6489 | 9.0155 | 9.2456 | 9.6918 | 8.8386 | 9.1246 | 9.4137 | 8.6371 | 9.9150 | 9.4009 | 10.1558 | 9.2141 | 9.3802 | 9.6211 | 10.1037 | 9.3262 | 9.8275 | 9.6073 | 9.8973 | 9.7803 | 9.1109 | 11.5949 | 8.4503 | 8.8111 | 10.3357 | 9.5493 | 9.5110 | 9.9297 | 8.3894 | 8.8081 | 9.5749 | 8.8917 | 9.0057 | 9.6279 | 9.0784 | 9.5935 | 9.2701 | 9.8943 | 9.8000 | 9.0666 | 8.8877 | 10.32900 |
| C1orf112 | 9.2978 | 8.5738 | 8.7915 | 9.1821 | 9.3634 | 8.7342 | 10.3220 | 8.5519 | 8.8915 | 9.0009 | 8.7092 | 9.3957 | 9.3717 | 9.2186 | 10.1070 | 8.4748 | 9.1571 | 8.7675 | 8.0634 | 9.3009 | 9.1832 | 10.4880 | 10.2870 | 10.2980 | 9.1519 | 10.7220 | 10.8870 | 9.2676 | 9.5905 | 9.2634 | 9.3551 | 9.1790 | 9.0655 | 10.8440 | 8.6519 | 9.3394 | 9.6030 | 9.5821 | 9.1530 | 9.6269 | 8.5321 | 8.4144 | 9.6821 | 9.3040 | 9.1665 | 8.5425 | 9.3884 | 9.0092 | 8.6884 | 9.5894 | 8.7478 | 9.4092 | 9.3009 | 9.8019 | 8.6842 | 9.4728 | 8.7092 | 8.9863 | 9.2957 | 9.3874 | 9.8592 | 9.3113 | 8.5144 | 10.1380 | 11.0050 | 8.6707 | 9.2311 | 9.2280 | 9.3186 | 9.0915 | 8.7853 | 9.0384 | 9.7655 | 8.8644 | 10.6480 | 10.3710 | 8.9644 | 9.0967 | 8.8321 | 10.6000 | 8.6030 | 9.0071 | 8.8884 | 8.4311 | 9.0592 | 8.3978 | 9.2905 | 10.3730 | 8.5050 | 8.6769 | 9.6144 | 9.0259 | 8.5540 | 10.3000 | 10.1190 | 9.3051 | 8.8998 | 10.3270 | 8.9634 | 8.9665 | 10.0280 | 10.7180 | 8.9269 | 8.9426 | 9.1967 | 10.2060 | 10.5170 | 8.8905 | 8.6728 | 8.6103 | 8.9363 | 9.6280 | 10.6210 | 8.9415 | 9.7249 | 8.7238 | 8.5217 | 8.4790 | 9.8832 | 8.9551 | 9.2509 | 9.1832 | 9.6269 | 9.3280 | 9.4405 | 8.3561 | 9.5571 | 8.7478 | 9.1728 | 8.8176 | 9.1738 | 10.8950 | 9.0280 | 9.5821 | 10.3810 | 9.0832 | 8.1634 | 8.7155 | 9.3821 | 10.0300 | 9.5832 | 8.8186 | 9.7082 | 9.0248 | 9.1488 | 9.7259 | 9.0457 | 8.9676 | 9.0603 | 10.1060 | 11.0960 | 9.0634 | 9.5311 | 9.1613 | 9.3946 | 11.5030 | 8.7050 | 9.7759 | 9.0384 | 10.0020 | 8.4665 | 9.4738 | 10.9030 | 8.8123 | 9.8405 | 10.2470 | 9.6394 | 9.9582 | 10.2050 | 8.5905 | 9.5530 | 8.4186 | 9.1936 | 9.3634 | 10.1580 | 9.4696 | 9.5655 | 8.5478 | 9.5092 | 10.5210 | 8.3978 | 9.3696 | 8.7821 | 8.9707 | 8.3655 | 9.1540 | 8.4863 | 9.9186 | 10.2170 | 9.5228 | 8.8759 | 8.6373 | 8.7436 | 11.2080 | 10.7120 | 9.1082 | 8.4509 | 11.5410 | 9.0592 | 10.0850 | 10.0560 | 8.9676 | 9.1780 | 9.9801 | 8.9123 | 10.2790 | 10.3360 | 8.4686 | 8.1071 | 10.1840 | 7.8405 | 10.6880 | 9.8863 | 9.2259 | 8.5488 | 9.5488 | 9.3655 | 8.3238 | 9.0551 | 10.3820 | 9.2894 | 8.9978 | 9.5009 | 9.5103 | 8.8092 | 8.7967 | 9.7040 | 9.2186 | 9.3874 | 9.1207 | 10.6150 | 8.9540 | 9.6686 | 9.5769 | 8.4165 | 9.7030 | 8.7915 | 9.5905 | 9.9592 | 10.0940 | 11.0070 | 9.2821 | 8.6384 | 9.4342 | 9.6165 | 8.1571 | 9.7009 | 10.3000 | 9.4009 | 8.9134 | 9.7613 | 9.6738 | 8.7196 | 9.0030 | 9.2790 | 9.7707 | 9.6374 | 8.3759 | 11.7090 | 10.3610 | 8.8176 | 9.0113 | 9.2603 | 9.5759 | 9.5530 | 9.7488 | 10.5950 | 8.8717 | 9.0811 | 10.2780 | 8.4071 | 8.8134 | 8.3821 | 8.7571 | 9.0009 | 8.5905 | 8.9988 | 9.6249 | 9.5592 | 8.7217 | 9.2238 | 11.6510 | 9.7342 | 10.3290 | 8.5415 | 8.8863 | 9.6499 | 10.7040 | 9.2321 | 7.9675 | 10.4440 | 9.4832 | 10.0630 | 8.8342 | 9.7926 | 8.8561 | 10.9310 | 9.2634 | 8.8321 | 8.6790 | 10.3760 | 9.1832 | 9.4957 | 10.1560 | 9.2228 | 9.9915 | 10.1250 | 10.0990 | 8.4186 | 9.2571 | 10.0510 | 9.1676 | 8.9519 | 9.5030 | 9.3238 | 9.2978 | 8.8696 | 8.6332 | 8.8478 | 9.4207 | 10.4000 | 9.0415 | 9.5353 | 9.9832 | 9.9082 | 8.2519 | 8.5290 | 8.9634 | 9.4019 | 8.0977 | 8.9301 | 9.3405 | 8.6978 | 8.8476 | 7.9455 | 9.4650 | 9.9620 | 9.7732 | 8.7879 | 9.9199 | 9.6059 | 8.6636 | 8.8133 | 9.2106 | 10.5760 | 8.6284 | 8.4728 | 10.3480 | 9.1636 | 10.2790 | 10.1990 | 8.6362 | 9.6577 | 9.1607 | 9.0178 | 9.1822 | 9.2742 | 10.2530 | 8.6470 | 9.2575 | 8.9249 | 8.8466 | 9.4386 | 9.0599 | 7.7244 | 8.9229 | 8.8838 | 9.5521 | 9.0061 | 9.0619 | 10.5840 | 8.7938 | 8.6020 | 8.0502 | 8.5766 | 9.6802 | 8.4425 | 9.2791 | 8.8192 | 10.1500 | 8.4249 | 8.4053 | 12.0140 | 9.5863 | 9.7624 | 9.8808 | 9.0041 | 10.7900 | 9.3730 | 9.8642 | 9.3818 | 10.3130 | 9.0668 | 9.0990 | 9.1773 | 9.1783 | 8.9523 | 9.5521 | 10.3600 | 8.6617 | 10.1640 | 8.1813 | 9.7497 | 9.8221 | 10.9560 | 10.1420 | 10.8180 | 9.5501 | 9.3994 | 9.7174 | 11.3300 | 9.0227 | 9.1920 | 8.8613 | 10.2540 | 10.6290 | 9.9738 | 10.0130 | 9.0589 | 9.5442 | 10.7800 | 10.5000 | 9.2986 | 8.3192 | 9.0922 | 9.8788 | 9.0521 | 9.3084 | 9.5100 | 8.4689 | 8.4161 | 10.8810 | 9.1030 | 11.3680 | 11.2610 | 9.9855 | 8.7321 | 8.7977 | 8.9356 | 8.5609 | 8.9533 | 9.1196 | 9.0863 | 10.5900 | 9.2791 | 10.5760 | 9.1284 | 9.1030 | 8.3662 | 9.2429 | 9.8182 | 11.4420 | 9.5765 | 8.2234 | 8.7449 | 9.9072 | 10.1800 | 9.9287 | 8.3202 | 9.3035 | 9.4669 | 9.7839 | 8.4552 | 8.2429 | 8.8936 | 8.3613 | 10.7790 | 8.7184 | 9.1059 | 8.1040 | 8.5462 | 11.3120 | 8.3525 | 10.3960 | 8.4777 | 9.1597 | 8.3505 | 9.3877 | 8.7742 | 9.3231 | 9.9013 | 8.8848 | 8.4269 | 9.7712 | 9.6430 | 9.4933 | 8.6940 | 10.0810 | 9.0266 | 9.6528 | 9.0893 | 8.8466 | 10.1740 | 9.0511 | 9.3319 | 10.3930 | 9.3505 | 10.0200 | 9.9835 | 9.1636 | 9.1284 | 10.3080 | 9.7693 | 9.9395 | 9.5080 | 8.3515 | 10.0990 | 8.5081 | 9.6744 | 9.0795 | 9.5853 | 8.5932 | 9.3290 | 8.9278 | 9.3662 | 8.6509 | 9.2781 | 9.8514 | 9.7213 | 8.8554 | 9.5403 | 8.3222 | 9.2253 | 10.1120 | 8.7351 | 7.9964 | 8.4758 | 9.5022 | 10.3810 | 8.3633 | 9.7203 | 9.4699 | 8.7791 | 8.2547 | 10.0170 | 9.8289 | 8.5521 | 8.7096 | 8.9034 | 9.1411 | 9.8896 | 8.6089 | 10.9990 | 9.2771 | 9.0589 | 8.9356 | 8.5697 | 9.3123 | 10.0910 | 8.9063 | 10.0500 | 9.9786 | 10.0480 | 9.0041 | 8.5198 | 8.7605 | 9.8495 | 9.6949 | 9.6724 | 8.5863 | 9.3789 | 8.5247 | 8.9630 | 9.3026 | 8.1656 | 9.3065 | 8.5678 | 9.8877 | 9.7810 | 9.4914 | 9.8152 | 9.0169 | 10.1260 | 8.7439 | 9.3984 | 8.6548 | 10.0760 | 9.2869 | 8.3858 | 8.8652 | 9.2664 | 9.1851 | 8.7126 | 9.7282 | 9.5266 | 9.1548 | 8.8613 | 8.4484 | 10.1340 | 8.5961 | 8.3867 | 9.6792 | 8.2987 | 9.2390 | 9.7311 | 9.1568 | 8.7282 | 9.2889 | 8.7439 | 9.9053 | 8.5179 | 9.5892 | 9.8622 | 10.8220 | 8.5922 | 8.9444 | 9.7556 | 8.4014 | 8.3241 | 10.6300 | 9.3231 | 9.8348 | 9.3084 | 10.1730 | 9.5530 | 8.2948 | 8.5580 | 8.5854 | 8.5169 | 8.8623 | 8.7859 | 9.9239 | 10.0790 | 8.6646 | 9.2429 | 10.6390 | 9.5638 | 8.7272 | 9.6479 | 9.6205 | 9.5207 | 8.8623 | 9.8603 | 9.4141 | 8.7722 | 9.5873 | 8.6715 | 9.5834 | 9.9718 | 9.0579 | 9.9610 | 8.6030 | 9.1685 | 9.0374 | 9.2566 | 8.9396 | 8.4533 | 9.1059 | 9.2712 | 9.0619 | 8.5824 | 9.9454 | 8.6783 | 9.2575 | 9.2174 | 9.9268 | 9.4483 | 8.3877 | 9.0169 | 9.5697 | 8.7165 | 8.7948 | 8.9650 | 9.8280 | 8.3956 | 9.8495 | 9.1959 | 9.0844 | 9.5569 | 8.2566 | 9.0951 | 8.8192 | 9.3251 | 9.3750 | 9.3378 | 8.9797 | 8.8838 | 9.9659 | 9.8700 | 9.3681 | 9.1930 | 8.6480 | 10.0340 | 9.2918 | 9.6323 | 9.8965 | 8.4014 | 9.2527 | 9.6440 | 8.7703 | 8.7576 | 9.5256 | 8.3280 | 8.5345 | 8.5413 | 11.2560 | 9.6342 | 8.3662 | 8.9435 | 9.5022 | 9.8250 | 10.7570 | 9.2624 | 9.7898 | 9.8974 | 9.4063 | 9.5569 | 10.7790 | 8.3515 | 9.1930 | 8.5139 | 10.2220 | 9.6196 | 10.0520 | 8.9630 | 9.5374 | 10.4410 | 8.5756 | 8.9151 | 10.3100 | 9.1215 | 11.7400 | 8.7713 | 10.3320 | 8.3368 | 11.0730 | 10.4940 | 8.8936 | 9.5980 | 8.8124 | 9.6704 | 10.3350 | 8.8740 | 9.4806 | 10.4180 | 9.5706 | 10.7340 | 8.2116 | 9.4209 | 9.9796 | 9.0296 | 8.5188 | 9.1489 | 8.1059 | 9.9454 | 10.5200 | 9.7947 | 9.0306 | 8.7879 | 9.1450 | 9.0315 | 8.2654 | 8.4562 | 9.6538 | 9.2076 | 8.6372 | 10.4860 | 7.8662 | 10.7540 | 9.5726 | 8.5609 | 8.3711 | 9.3172 | 9.2752 | 10.1170 | 9.4532 | 9.1078 | 10.3730 | 8.9464 | 9.5178 | 9.3026 | 9.0981 | 8.7801 | 9.4434 | 10.4220 | 10.4440 | 10.0040 | 9.0873 | 9.3642 | 10.6020 | 9.3838 | 9.7174 | 9.8104 | 10.1290 | 8.9376 | 9.4043 | 8.6715 | 9.0531 | 9.5080 | 10.2470 | 9.6333 | 9.5775 | 8.6460 | 10.7590 | 8.9718 | 8.5404 | 9.5931 | 9.5824 | 9.8387 | 9.8642 | 9.4748 | 9.3671 | 10.0160 | 9.4806 | 9.8299 | 8.3192 | 9.7321 | 8.2282 | 8.8867 | 9.8730 | 10.5270 | 9.8113 | 8.0149 | 8.7106 | 9.0462 | 8.2302 | 9.2791 | 8.4132 | 9.1372 | 9.9082 | 8.6499 | 8.6010 | 9.3613 | 9.9415 | 9.1460 | 10.8510 | 10.1220 | 9.9013 | 10.4530 | 9.7536 | 8.7497 | 9.0589 | 10.9770 | 8.9239 | 10.3250 | 10.4840 | 8.9415 | 9.3407 | 9.6176 | 9.6978 | 10.2840 | 9.1049 | 10.4870 | 9.8299 | 8.9983 | 9.4160 | 9.6313 | 8.4719 | 9.2487 | 9.3280 | 9.0374 | 10.2320 | 8.3877 | 9.2644 | 8.8261 | 10.7090 | 9.8231 | 9.4072 | 9.9415 | 9.9336 | 8.9513 | 9.8015 | 9.9239 | 9.7057 | 9.8867 | 9.0188 | 9.6636 | 10.1020 | 8.7722 | 8.9200 | 11.3860 | 8.9650 | 9.2155 | 10.3240 | 9.1303 | 8.9347 | 8.8221 | 7.8614 | 10.3514 | 10.3025 | 8.9396 | 9.3094 | 7.6471 | 9.2312 | 11.3592 | 8.2616 | 9.2507 | 8.9562 | 9.1803 | 8.8457 | 9.6000 | 9.2194 | 8.8780 | 10.2135 | 9.2703 | 9.5785 | 7.7861 | 8.3927 | 9.6783 | 8.4073 | 9.7439 | 9.0639 | 9.5775 | 9.3544 | 9.2635 | 8.5238 | 9.7086 | 8.8085 | 9.7380 | 9.7595 | 8.8652 | 8.9328 | 7.6119 | 9.7302 | 9.2752 | 8.9308 | 8.8124 | 11.8905 | 9.1363 | 8.6294 | 8.7596 | 8.7126 | 9.5237 | 9.4953 | 8.4377 | 8.3242 | 10.1910 | 8.5179 | 9.3642 | 9.3691 | 8.4299 | 8.5042 | 9.1734 | 9.7947 | 9.3995 | 9.1010 | 9.8172 | 9.8417 | 9.6626 | 8.2195 | 10.2869 | 9.1891 | 9.6969 | 9.2586 | 8.5052 | 10.0393 | 9.1705 | 9.6216 | 8.1148 | 9.7145 | 10.8455 | 9.5687 | 9.4924 | 9.2478 | 10.1421 | 9.6529 | 8.8222 | 9.5266 | 8.7410 | 9.3975 | 9.0619 | 9.0140 | 9.6372 | 8.5854 | 10.8318 | 8.6568 | 12.1429 | 9.7067 | 9.0609 | 9.2860 | 9.0619 | 9.0854 | 8.6793 | 8.8985 | 8.7879 | 9.5296 | 8.5786 | 9.9151 | 10.7663 | 9.1040 | 8.7850 | 9.5374 | 9.3662 | 8.0698 | 9.1069 | 8.5815 | 10.63100 |
| FGR | 7.5326 | 8.0202 | 8.0026 | 8.5236 | 9.4199 | 10.9400 | 9.6857 | 9.0358 | 9.6069 | 9.2721 | 9.4824 | 8.6305 | 9.4001 | 10.2890 | 8.2569 | 8.2340 | 8.0743 | 10.0870 | 8.9420 | 9.2602 | 8.6353 | 9.1871 | 9.4652 | 8.5363 | 7.9555 | 10.6620 | 8.9812 | 9.2474 | 10.0090 | 8.9711 | 9.1158 | 10.6220 | 8.6503 | 9.4221 | 8.4012 | 9.4714 | 9.5026 | 9.8419 | 9.9004 | 8.5218 | 8.7277 | 9.5251 | 9.4459 | 9.2069 | 9.6786 | 9.3262 | 8.9900 | 9.1656 | 9.3887 | 8.8892 | 8.4919 | 9.6879 | 8.7264 | 9.8027 | 10.0770 | 8.3572 | 8.4958 | 8.0941 | 8.1526 | 10.5220 | 10.4680 | 9.3121 | 9.4349 | 9.0837 | 10.4380 | 8.2442 | 8.8844 | 7.5696 | 8.6705 | 8.7357 | 8.5597 | 9.9361 | 7.6162 | 8.0813 | 9.3161 | 8.3924 | 8.9508 | 8.9020 | 8.0114 | 9.2197 | 9.5418 | 9.9589 | 8.9570 | 9.6830 | 8.4395 | 9.9220 | 8.4668 | 9.4274 | 8.7308 | 8.9645 | 9.0036 | 7.8596 | 7.8913 | 9.1594 | 9.7724 | 9.0824 | 9.2069 | 8.9310 | 9.0067 | 9.2408 | 8.1284 | 7.8820 | 9.8978 | 9.2017 | 8.8835 | 10.2510 | 8.9218 | 9.3513 | 8.4677 | 9.8203 | 8.0329 | 9.6716 | 9.1722 | 8.7612 | 10.8960 | 9.6038 | 7.7091 | 8.9319 | 8.5064 | 9.0177 | 8.8074 | 9.3394 | 9.0925 | 10.3060 | 8.4923 | 9.3539 | 8.1641 | 8.9491 | 9.5713 | 9.0529 | 9.2721 | 9.3816 | 8.9887 | 8.0910 | 8.7612 | 9.7706 | 8.3269 | 8.1557 | 8.3242 | 6.9650 | 9.2707 | 9.1339 | 9.3812 | 9.1260 | 7.9581 | 9.0864 | 10.7430 | 10.3880 | 8.2750 | 8.7440 | 9.1079 | 10.0580 | 8.4866 | 9.0318 | 7.6488 | 8.6758 | 9.7442 | 10.0450 | 9.4173 | 9.3420 | 9.1823 | 7.9295 | 9.0327 | 8.3000 | 8.6481 | 9.4573 | 9.2989 | 8.6345 | 9.3513 | 8.2926 | 9.5326 | 9.6760 | 8.6811 | 8.8179 | 8.1707 | 7.8706 | 8.5689 | 8.1438 | 9.8881 | 10.2150 | 9.2100 | 9.1858 | 8.7748 | 7.9639 | 8.2706 | 12.1850 | 8.4193 | 8.6626 | 9.3627 | 9.5814 | 8.9174 | 8.8426 | 8.6661 | 9.3869 | 9.2030 | 8.8298 | 8.8615 | 8.2600 | 7.5920 | 9.1656 | 9.6866 | 9.2078 | 8.3630 | 8.2820 | 9.0798 | 9.4027 | 9.3240 | 9.7710 | 7.9969 | 7.9366 | 10.4240 | 9.5836 | 8.5685 | 8.6609 | 8.6763 | 10.2850 | 8.8862 | 9.2641 | 10.1350 | 7.6233 | 7.8547 | 9.3579 | 9.2505 | 9.4560 | 9.2223 | 9.8907 | 9.3997 | 8.9566 | 9.0226 | 8.8866 | 8.3137 | 8.7656 | 11.0700 | 7.7280 | 9.4815 | 7.8274 | 9.9585 | 9.6729 | 9.9075 | 9.2065 | 8.5839 | 9.3130 | 9.4789 | 8.9341 | 8.4875 | 9.3007 | 8.5306 | 8.5579 | 9.0767 | 9.3222 | 10.3070 | 11.0550 | 8.3911 | 9.1079 | 8.6626 | 8.5090 | 9.4635 | 9.5554 | 9.6848 | 9.4560 | 9.5493 | 8.7031 | 8.9504 | 8.6626 | 8.1095 | 7.8556 | 10.2860 | 9.2487 | 8.8510 | 9.4085 | 10.0100 | 9.8463 | 9.0252 | 9.1541 | 9.2483 | 9.2527 | 9.3394 | 8.8135 | 6.8919 | 9.3983 | 8.9526 | 9.6993 | 9.5735 | 9.1775 | 8.8228 | 8.8452 | 9.4586 | 8.7233 | 7.8213 | 8.7295 | 8.6186 | 9.8661 | 9.1343 | 9.5515 | 9.3108 | 8.0910 | 9.0472 | 8.4373 | 9.2122 | 9.0019 | 8.5729 | 8.1531 | 7.5265 | 9.1929 | 8.6815 | 9.2052 | 8.2046 | 10.3950 | 7.8288 | 9.1198 | 9.7231 | 10.1230 | 9.3319 | 9.3293 | 8.8822 | 9.6676 | 9.5229 | 8.9887 | 10.9740 | 9.8406 | 7.1243 | 7.9331 | 10.0980 | 10.4000 | 9.8049 | 9.3521 | 9.1172 | 8.9222 | 9.1475 | 11.1270 | 9.0872 | 7.6114 | 8.1293 | 8.9800 | 7.5842 | 7.6298 | 10.2610 | 9.8453 | 8.8959 | 7.8831 | 8.6150 | 9.2100 | 8.9138 | 9.1438 | 9.4516 | 9.8381 | 9.5661 | 8.3054 | 9.3648 | 10.2790 | 9.3174 | 10.3850 | 9.2628 | 9.8381 | 8.5434 | 8.3609 | 7.5896 | 9.4274 | 8.8995 | 8.5210 | 9.1626 | 9.2019 | 9.0973 | 8.3466 | 8.3304 | 8.6660 | 10.4410 | 9.6851 | 9.5160 | 8.8476 | 9.5276 | 10.6480 | 9.3111 | 9.2386 | 8.5810 | 9.7916 | 9.8158 | 9.5849 | 8.1640 | 7.3247 | 7.8347 | 8.9783 | 8.6418 | 8.6087 | 9.8632 | 9.6744 | 8.0110 | 8.8843 | 10.0960 | 8.4647 | 9.9043 | 9.4489 | 8.6418 | 8.3474 | 9.5097 | 8.8288 | 8.8136 | 9.5053 | 8.5192 | 9.4659 | 9.0364 | 8.1300 | 9.3621 | 8.3653 | 9.5420 | 9.8855 | 9.6386 | 9.1169 | 9.1796 | 9.7129 | 9.0346 | 8.5899 | 8.3197 | 8.9335 | 8.8369 | 7.8866 | 9.7728 | 9.9240 | 9.8999 | 10.4130 | 9.2404 | 11.0800 | 8.9604 | 9.9285 | 9.6323 | 9.2100 | 8.4181 | 8.1828 | 8.4101 | 8.9281 | 9.2619 | 9.6601 | 10.3530 | 9.4247 | 8.8029 | 9.2252 | 8.6060 | 8.4790 | 9.1429 | 9.2395 | 8.5398 | 8.6866 | 8.1327 | 9.4766 | 8.6427 | 8.6803 | 9.0642 | 8.5962 | 8.1157 | 9.3120 | 9.2494 | 7.7551 | 9.0856 | 10.8040 | 8.9568 | 8.4137 | 10.5490 | 9.6216 | 9.3192 | 8.8977 | 7.9412 | 8.4897 | 9.7665 | 9.8945 | 10.1820 | 10.3060 | 8.3340 | 8.3564 | 9.4068 | 9.4704 | 9.8193 | 9.3952 | 11.3400 | 8.8100 | 9.8471 | 8.4298 | 9.6010 | 8.8718 | 9.2315 | 10.7640 | 8.3376 | 8.9478 | 8.7787 | 11.0470 | 9.8328 | 10.0420 | 8.8673 | 8.1613 | 9.3183 | 9.5795 | 11.2210 | 8.9273 | 9.9571 | 9.7173 | 8.7304 | 8.7510 | 11.1910 | 9.4095 | 9.2019 | 8.5031 | 8.7716 | 9.2055 | 9.5724 | 9.4400 | 7.3892 | 9.9016 | 8.7411 | 8.5828 | 8.9738 | 9.1858 | 10.0740 | 10.5470 | 8.7313 | 10.1170 | 9.2288 | 8.9621 | 9.3048 | 9.3004 | 8.7698 | 8.7018 | 9.8945 | 10.5380 | 8.6696 | 9.6270 | 9.3388 | 8.1864 | 9.1930 | 9.4095 | 9.6341 | 9.6502 | 8.0316 | 7.8383 | 8.9004 | 8.3242 | 9.5572 | 9.0946 | 9.6878 | 8.4664 | 12.4780 | 9.7567 | 7.7775 | 10.2980 | 9.0114 | 9.3791 | 9.7370 | 9.0033 | 8.4673 | 9.8936 | 8.0280 | 8.1935 | 8.9362 | 9.1590 | 9.3782 | 8.4110 | 8.7841 | 9.6126 | 7.8580 | 8.1533 | 8.6356 | 9.8676 | 8.7975 | 9.6627 | 9.5992 | 9.6744 | 10.1040 | 9.2771 | 8.4280 | 8.4566 | 7.8401 | 8.1873 | 9.9106 | 9.5303 | 7.9189 | 9.2977 | 10.0610 | 8.5389 | 9.9652 | 10.7820 | 9.1814 | 10.5580 | 8.7751 | 8.5846 | 9.2136 | 7.6943 | 9.3558 | 10.4120 | 7.6039 | 7.9475 | 9.3299 | 8.0889 | 8.9290 | 8.7241 | 7.8723 | 9.4963 | 9.0597 | 8.7062 | 9.5563 | 8.9809 | 9.0937 | 9.4525 | 8.4137 | 7.7408 | 9.1653 | 9.4775 | 10.8860 | 9.2789 | 7.7497 | 8.8986 | 8.8780 | 9.5956 | 9.8569 | 9.2932 | 8.5568 | 8.5649 | 8.0799 | 9.0230 | 10.2890 | 10.1560 | 9.4677 | 9.9115 | 9.3558 | 9.4131 | 9.4516 | 9.4194 | 10.1490 | 9.8158 | 10.1970 | 8.1238 | 8.9317 | 8.8360 | 9.0230 | 8.5971 | 8.5872 | 8.4190 | 9.4561 | 8.5828 | 8.9666 | 9.9276 | 9.2959 | 8.2964 | 8.9568 | 8.9684 | 9.3388 | 8.2114 | 9.5258 | 9.8471 | 12.4140 | 8.6740 | 8.6964 | 9.0123 | 9.5858 | 9.1840 | 8.0611 | 7.9994 | 8.6875 | 8.5157 | 8.8897 | 9.3469 | 11.2900 | 8.7501 | 9.3388 | 8.8906 | 10.2430 | 9.1715 | 8.3680 | 9.1429 | 10.1370 | 10.5640 | 9.8712 | 8.9836 | 8.7170 | 9.3487 | 10.8110 | 9.2905 | 10.0550 | 11.1090 | 8.3099 | 9.7442 | 8.4629 | 8.9031 | 8.8163 | 8.8610 | 8.0226 | 9.3201 | 9.1259 | 7.9904 | 7.9591 | 8.2938 | 8.7152 | 8.9380 | 8.0468 | 10.8820 | 10.1450 | 9.1411 | 8.6060 | 8.4682 | 8.3143 | 9.9034 | 9.3800 | 7.5735 | 9.1554 | 8.3967 | 8.3993 | 9.0606 | 9.1518 | 9.6305 | 9.8372 | 10.3620 | 9.6037 | 8.3125 | 9.6404 | 9.0310 | 9.7764 | 7.8231 | 8.5711 | 9.0328 | 9.1697 | 8.1461 | 9.2333 | 8.1560 | 8.9675 | 8.8431 | 9.7728 | 7.8151 | 9.9589 | 8.3537 | 9.5661 | 9.7648 | 9.5017 | 8.1300 | 9.3022 | 9.2887 | 9.3236 | 7.9860 | 9.0946 | 7.9278 | 8.6901 | 8.6606 | 8.4414 | 8.8002 | 8.1819 | 8.8163 | 9.5706 | 9.8077 | 9.5921 | 8.1032 | 8.2750 | 8.3260 | 7.6406 | 8.3823 | 8.1774 | 7.1413 | 8.4503 | 9.6601 | 7.1583 | 8.7322 | 7.8115 | 8.3448 | 7.9627 | 9.8480 | 8.9290 | 8.7197 | 10.5580 | 7.6191 | 8.9586 | 8.2150 | 9.2995 | 9.4400 | 8.5157 | 8.6535 | 8.3949 | 9.0740 | 9.0391 | 8.4852 | 9.0955 | 9.2109 | 7.5431 | 9.5607 | 8.4271 | 9.1903 | 7.4572 | 9.2172 | 10.4470 | 7.7587 | 7.7426 | 8.1622 | 9.0955 | 9.5903 | 9.1876 | 7.5099 | 10.4960 | 9.4507 | 7.2138 | 8.1059 | 9.9142 | 8.8297 | 9.1330 | 9.1196 | 8.7331 | 8.8109 | 9.3308 | 7.3077 | 9.3657 | 9.2010 | 8.9147 | 9.6001 | 9.6216 | 8.1953 | 8.0343 | 10.3650 | 9.8166 | 8.0790 | 8.4387 | 10.3080 | 8.2991 | 9.5956 | 8.1882 | 9.1304 | 7.7614 | 9.3594 | 11.8290 | 8.4638 | 9.0847 | 8.0853 | 9.3988 | 8.1694 | 10.0200 | 9.0230 | 9.3728 | 9.5670 | 7.9162 | 8.6606 | 8.8950 | 10.0740 | 8.8763 | 8.3967 | 7.3050 | 8.3340 | 9.3943 | 9.3827 | 9.8963 | 9.5831 | 8.8754 | 9.5384 | 8.5899 | 8.4262 | 7.7811 | 9.9643 | 9.0400 | 8.7456 | 8.5219 | 8.3850 | 8.7492 | 8.9613 | 9.4570 | 8.2794 | 8.3304 | 9.0391 | 8.8816 | 9.0874 | 10.1300 | 8.9961 | 9.7048 | 9.5366 | 8.2750 | 8.4727 | 8.0611 | 9.2333 | 9.4176 | 9.8247 | 8.6499 | 9.2655 | 9.0409 | 9.0436 | 8.9264 | 8.1658 | 8.8933 | 9.3505 | 9.7576 | 8.9470 | 8.0146 | 9.1519 | 12.8365 | 8.6687 | 8.4611 | 9.7156 | 9.0096 | 9.1814 | 8.7009 | 7.5091 | 9.7836 | 8.0862 | 9.0204 | 8.8656 | 8.6678 | 9.4570 | 8.3546 | 8.0084 | 10.2381 | 7.0590 | 9.0204 | 8.6768 | 9.1671 | 8.4862 | 8.9228 | 9.5429 | 7.6460 | 9.4615 | 9.6896 | 9.0248 | 8.7054 | 8.9380 | 8.0155 | 7.7381 | 8.3233 | 9.1644 | 8.6973 | 9.3040 | 9.1143 | 9.6458 | 9.8337 | 8.2687 | 8.6535 | 7.9359 | 7.8876 | 8.8423 | 9.6225 | 8.9121 | 7.7883 | 9.5026 | 8.4933 | 9.2637 | 9.1841 | 9.1071 | 8.9998 | 7.9207 | 9.1608 | 8.7126 | 9.4230 | 9.0660 | 8.1247 | 8.1578 | 8.7466 | 8.8163 | 9.7827 | 7.8357 | 8.8208 | 9.0311 | 8.2795 | 9.6216 | 8.1828 | 9.2288 | 9.3827 | 8.8665 | 8.8342 | 8.1193 | 8.3081 | 8.6616 | 8.1542 | 8.3171 | 9.3120 | 8.8718 | 9.4373 | 9.6154 | 9.3729 | 7.9162 | 9.4203 | 9.4615 | 8.8342 | 7.7891 | 8.9810 | 8.6302 | 8.9380 | 8.6660 | 9.7648 | 9.1689 | 9.4713 | 8.6616 | 8.3376 | 9.3783 | 9.6100 | 9.2924 | 8.9479 | 8.4593 | 9.1420 | 9.8480 | 8.34860 |
| CFH | 8.7210 | 8.3135 | 8.3359 | 9.2180 | 9.9531 | 9.8552 | 8.0946 | 10.3120 | 9.7288 | 9.8100 | 9.2622 | 10.0230 | 9.3781 | 9.4571 | 8.8261 | 9.8697 | 7.1231 | 9.9766 | 8.6246 | 9.7201 | 9.8368 | 9.5647 | 8.6015 | 9.1959 | 9.1383 | 8.6105 | 9.3390 | 8.5232 | 9.9726 | 7.5273 | 8.9141 | 10.3980 | 9.9570 | 9.0760 | 8.8989 | 8.9489 | 9.9976 | 8.9550 | 9.8049 | 9.1966 | 9.1405 | 8.8199 | 9.4097 | 10.3520 | 9.7397 | 9.6545 | 8.9905 | 8.4754 | 9.6285 | 9.3289 | 9.0883 | 8.4656 | 8.5873 | 8.7732 | 9.2803 | 8.8434 | 10.0300 | 9.6756 | 9.9063 | 8.5783 | 10.8430 | 10.1100 | 9.5144 | 8.7858 | 9.2767 | 9.6614 | 8.2222 | 9.6901 | 8.9869 | 9.2995 | 10.1200 | 9.4350 | 9.4908 | 8.7800 | 8.9246 | 9.1191 | 9.8632 | 8.2069 | 10.1200 | 8.5525 | 8.8514 | 10.1670 | 8.7311 | 10.3450 | 9.4013 | 10.2830 | 9.1727 | 9.0238 | 8.1508 | 9.2043 | 9.4966 | 10.1660 | 8.5395 | 8.9155 | 8.4982 | 9.0945 | 9.3321 | 8.7145 | 10.2600 | 8.8014 | 9.0829 | 9.3209 | 9.5647 | 9.5227 | 9.0003 | 11.0290 | 10.2000 | 9.0014 | 9.0764 | 9.9186 | 8.9684 | 9.5698 | 9.2615 | 9.9165 | 9.1264 | 8.0950 | 8.5544 | 8.7105 | 8.7482 | 8.6373 | 10.1990 | 9.2463 | 9.5343 | 9.5977 | 10.1790 | 10.3220 | 9.7074 | 9.6625 | 9.7270 | 9.5912 | 8.7192 | 8.0562 | 8.7355 | 9.8940 | 8.4699 | 9.1778 | 8.6572 | 9.2492 | 10.6490 | 7.1683 | 9.3263 | 9.8397 | 9.1133 | 10.8340 | 9.4368 | 9.5973 | 10.5550 | 10.3010 | 11.0650 | 8.4468 | 8.1711 | 9.7263 | 9.0767 | 9.8150 | 9.2474 | 7.7538 | 9.4531 | 8.6551 | 9.6843 | 9.7165 | 9.1894 | 8.8108 | 9.1597 | 10.2750 | 9.1521 | 8.6120 | 8.9880 | 7.8269 | 9.9480 | 10.8460 | 8.8460 | 9.7969 | 9.7864 | 8.7253 | 9.4078 | 9.2427 | 9.3473 | 9.1148 | 10.0240 | 9.0387 | 10.0410 | 9.7719 | 9.3426 | 9.6680 | 9.2046 | 10.1660 | 8.4569 | 8.9644 | 9.1180 | 9.6723 | 8.9815 | 9.9933 | 8.7779 | 9.1173 | 8.0599 | 9.4557 | 9.0354 | 9.4281 | 9.1083 | 10.0310 | 8.5145 | 9.6154 | 8.7724 | 10.1290 | 9.2977 | 9.4368 | 8.7674 | 9.9125 | 9.2582 | 9.7324 | 10.7200 | 8.4949 | 9.3622 | 9.1260 | 9.7379 | 9.7697 | 9.3079 | 10.7740 | 9.5629 | 8.4910 | 10.1360 | 10.1730 | 8.3345 | 9.6263 | 8.7159 | 9.2285 | 10.2060 | 9.3068 | 9.9994 | 9.1137 | 8.0660 | 10.4750 | 9.5614 | 7.9965 | 8.6018 | 8.5699 | 9.1202 | 8.6333 | 9.0036 | 8.9833 | 9.7415 | 8.6565 | 9.9099 | 10.1140 | 8.5247 | 9.8962 | 8.3924 | 8.8195 | 8.8079 | 9.4763 | 8.5507 | 9.0622 | 9.5336 | 8.2895 | 8.7304 | 7.6875 | 10.6330 | 9.6020 | 9.5404 | 9.4354 | 8.8536 | 8.9235 | 9.6013 | 9.2557 | 7.9298 | 8.7786 | 8.3819 | 8.4109 | 9.6926 | 10.4310 | 9.3843 | 9.4803 | 9.7625 | 9.8810 | 10.3530 | 9.0735 | 9.4383 | 8.5308 | 7.8965 | 9.9458 | 9.2901 | 8.8304 | 8.8858 | 8.9427 | 9.4923 | 9.5140 | 9.1249 | 9.2753 | 9.4365 | 9.7382 | 8.4739 | 9.5230 | 9.0057 | 9.9770 | 8.4087 | 9.4100 | 8.6406 | 7.7824 | 10.9230 | 9.7085 | 7.6795 | 9.8810 | 8.0215 | 9.8882 | 9.7324 | 9.9012 | 9.4941 | 9.1626 | 9.0702 | 9.3111 | 9.2883 | 9.7759 | 9.7658 | 9.2492 | 10.3550 | 8.8539 | 9.9494 | 9.9288 | 9.8962 | 9.0934 | 7.5371 | 10.2200 | 8.5120 | 10.1650 | 9.3292 | 9.6919 | 9.6694 | 8.5750 | 9.3832 | 9.8734 | 10.2840 | 8.2522 | 8.6891 | 9.4812 | 7.6221 | 9.1099 | 9.2278 | 9.8658 | 9.5607 | 6.9592 | 9.3118 | 8.7307 | 9.6652 | 9.1496 | 10.0240 | 9.2189 | 9.0652 | 8.7112 | 10.0140 | 10.6350 | 8.9084 | 9.5693 | 8.9087 | 9.3435 | 9.8243 | 8.6288 | 9.1160 | 10.1980 | 8.9892 | 9.5467 | 9.2761 | 10.2100 | 9.3793 | 10.1600 | 7.9435 | 9.2106 | 9.9518 | 9.1828 | 9.2396 | 8.9400 | 8.5090 | 9.3355 | 9.1480 | 9.2595 | 9.4243 | 9.6019 | 10.1020 | 9.1665 | 8.0429 | 7.9004 | 9.3623 | 8.9064 | 8.1429 | 9.1607 | 8.8215 | 10.2860 | 9.0556 | 8.8157 | 9.5991 | 9.7569 | 9.9137 | 9.4198 | 10.4800 | 9.5422 | 8.6905 | 11.2090 | 9.8962 | 9.7706 | 9.7943 | 8.7953 | 9.5770 | 9.2138 | 9.5387 | 9.9540 | 9.0710 | 9.4863 | 9.9307 | 9.2473 | 9.1323 | 9.6824 | 8.7940 | 9.6866 | 9.6655 | 9.5955 | 8.3221 | 9.4144 | 10.0850 | 9.1000 | 9.5527 | 9.8236 | 9.7559 | 9.4422 | 8.6205 | 9.4662 | 9.6949 | 8.2803 | 10.0200 | 9.0234 | 8.7218 | 10.0550 | 8.9496 | 9.2678 | 9.6115 | 9.9882 | 10.0660 | 9.9588 | 9.5508 | 8.7020 | 9.3326 | 8.9026 | 9.1540 | 8.8163 | 9.8847 | 9.0671 | 8.9042 | 8.2662 | 9.7428 | 9.2940 | 7.8694 | 11.1560 | 8.8981 | 7.5768 | 8.6109 | 10.7240 | 10.3260 | 8.4806 | 9.1537 | 9.1419 | 9.1860 | 8.7962 | 7.9985 | 10.3350 | 9.0486 | 9.8144 | 9.7342 | 8.5719 | 7.7480 | 8.6176 | 9.3556 | 9.6534 | 9.2384 | 9.1662 | 9.9610 | 8.1077 | 9.0802 | 9.4262 | 9.2294 | 9.0122 | 8.8064 | 9.7620 | 10.0260 | 9.7083 | 8.3601 | 10.2960 | 9.6585 | 9.1617 | 9.2064 | 9.1055 | 8.5969 | 9.0135 | 9.4876 | 10.1900 | 9.4467 | 8.9438 | 7.7854 | 8.9754 | 9.0068 | 8.8812 | 9.7320 | 9.4246 | 8.9943 | 9.7265 | 9.4003 | 9.9837 | 8.3295 | 10.9570 | 9.7914 | 9.4642 | 8.5665 | 11.0520 | 9.7971 | 9.6039 | 9.9879 | 10.3000 | 9.8556 | 7.7931 | 8.5291 | 9.2850 | 9.6518 | 9.0310 | 9.3534 | 9.6805 | 9.0905 | 9.3240 | 8.7940 | 9.2761 | 10.1230 | 9.2936 | 8.9876 | 10.2180 | 9.0074 | 9.2524 | 9.7562 | 9.1080 | 9.1946 | 9.1515 | 10.1080 | 10.2100 | 10.9390 | 10.0510 | 8.4646 | 9.9562 | 7.9838 | 9.7099 | 9.1326 | 9.5377 | 9.9492 | 10.1890 | 7.8471 | 9.3773 | 9.4125 | 9.5374 | 8.3320 | 9.0467 | 9.5313 | 9.6690 | 8.8729 | 9.8572 | 8.7614 | 9.8310 | 9.1601 | 7.9502 | 9.0387 | 8.1557 | 10.1230 | 9.2253 | 8.6956 | 9.4099 | 9.6521 | 9.1262 | 9.9716 | 9.9780 | 9.2869 | 10.1000 | 9.2694 | 9.3726 | 9.6208 | 9.3895 | 9.6543 | 9.5131 | 8.9809 | 9.1543 | 9.0413 | 8.5544 | 9.2719 | 11.3320 | 9.2297 | 8.5918 | 8.8080 | 8.6793 | 10.1640 | 10.0260 | 8.8528 | 10.3080 | 10.0200 | 8.7272 | 8.5374 | 8.9828 | 10.3990 | 8.6818 | 9.4729 | 8.8764 | 8.8438 | 8.6991 | 10.0370 | 9.2323 | 8.9093 | 10.2630 | 9.3987 | 10.4380 | 9.6320 | 9.7147 | 9.3441 | 8.4611 | 8.0052 | 10.0600 | 9.1700 | 10.2130 | 10.5120 | 8.9572 | 10.1480 | 10.6530 | 9.3323 | 9.2879 | 10.1590 | 9.3799 | 8.7991 | 9.0732 | 8.9435 | 8.4560 | 8.8461 | 9.9320 | 8.7793 | 9.1400 | 9.5074 | 9.4010 | 10.8110 | 9.3981 | 9.4361 | 9.4569 | 10.1750 | 9.5470 | 9.2119 | 8.5748 | 10.0650 | 8.2480 | 10.2400 | 9.3527 | 8.8416 | 9.3655 | 9.0317 | 8.0423 | 9.1448 | 9.5617 | 7.2819 | 9.9291 | 8.3454 | 10.3940 | 9.2288 | 9.2857 | 9.7160 | 9.8930 | 9.2508 | 9.1968 | 9.0869 | 9.5684 | 9.7371 | 10.2650 | 9.3655 | 8.5426 | 9.6607 | 8.5608 | 9.8444 | 9.5885 | 9.7131 | 9.4965 | 10.2180 | 10.2880 | 8.6774 | 9.2237 | 9.5182 | 9.3582 | 7.9905 | 10.0700 | 9.1154 | 8.2748 | 9.8875 | 8.8259 | 9.4591 | 9.4604 | 8.2253 | 9.6045 | 9.6773 | 8.0442 | 9.2269 | 8.5691 | 8.8400 | 9.0687 | 10.1230 | 9.3125 | 9.4387 | 7.5311 | 7.7285 | 8.6908 | 8.6560 | 10.1030 | 8.9253 | 7.4963 | 9.8508 | 8.6953 | 8.8652 | 9.3745 | 9.3681 | 7.9224 | 10.1750 | 9.5824 | 9.7415 | 8.6790 | 9.3438 | 8.0528 | 10.1330 | 8.4755 | 9.1441 | 8.1461 | 9.9668 | 9.0719 | 9.7681 | 10.0180 | 9.9850 | 9.0390 | 9.8211 | 9.3163 | 9.0499 | 9.5700 | 8.1867 | 8.5381 | 7.5579 | 8.1336 | 7.7525 | 8.4981 | 9.6380 | 8.8639 | 8.9026 | 9.1029 | 8.5988 | 9.4288 | 9.3396 | 8.6464 | 8.9454 | 9.0384 | 9.5722 | 8.2582 | 9.1387 | 9.2850 | 8.1649 | 8.6818 | 7.2563 | 7.2557 | 8.8857 | 9.3534 | 10.5020 | 9.0758 | 9.4521 | 8.6860 | 10.4950 | 8.9662 | 10.0550 | 8.7981 | 9.1841 | 9.4182 | 9.6023 | 9.1636 | 9.8885 | 8.6767 | 9.4323 | 8.8671 | 8.5406 | 9.2585 | 10.1810 | 10.5560 | 10.1430 | 8.9403 | 10.1500 | 10.4830 | 8.4547 | 9.0841 | 9.8153 | 9.1869 | 10.1930 | 7.1845 | 10.4050 | 9.9853 | 9.1837 | 10.4200 | 10.2150 | 9.8185 | 9.9118 | 10.3350 | 10.5500 | 9.4096 | 9.7802 | 9.2272 | 9.5029 | 9.6093 | 8.6441 | 9.6668 | 7.7560 | 9.3872 | 7.6017 | 10.0150 | 8.5218 | 8.3445 | 9.5042 | 9.4074 | 8.1819 | 9.7566 | 8.9345 | 9.5026 | 10.4190 | 9.9732 | 10.1420 | 8.9585 | 9.0569 | 7.9058 | 9.0617 | 9.8016 | 9.5872 | 9.8681 | 8.5620 | 9.6550 | 9.1809 | 9.9559 | 8.0205 | 10.2290 | 10.2960 | 9.0068 | 8.9246 | 9.5007 | 9.6454 | 7.7017 | 9.0569 | 9.2799 | 8.9595 | 9.9361 | 8.7393 | 9.1649 | 10.2000 | 10.2850 | 8.6972 | 8.6291 | 8.7195 | 8.9262 | 9.8153 | 9.3087 | 9.2742 | 9.6601 | 9.2416 | 9.1700 | 10.4980 | 9.9086 | 9.2879 | 10.2790 | 8.7604 | 9.7920 | 10.5230 | 8.9390 | 9.8665 | 8.8675 | 9.6856 | 9.5540 | 8.7633 | 9.3141 | 9.3390 | 9.2885 | 8.8895 | 8.4167 | 8.8084 | 10.1897 | 8.6339 | 8.6904 | 8.6952 | 9.7501 | 8.2313 | 8.5713 | 9.1058 | 10.2217 | 8.8208 | 9.2291 | 9.1728 | 9.3575 | 8.7725 | 9.6009 | 10.0073 | 8.0381 | 9.0179 | 9.1818 | 9.5636 | 9.4406 | 8.2921 | 8.7582 | 9.5527 | 8.3499 | 10.2728 | 10.3613 | 10.3198 | 10.1651 | 6.9512 | 9.8265 | 9.9003 | 9.2383 | 9.6281 | 8.2585 | 9.5335 | 8.6425 | 9.0195 | 9.1051 | 9.1371 | 8.6991 | 8.7578 | 7.8467 | 9.4703 | 8.9364 | 9.1712 | 9.1246 | 10.7485 | 9.3613 | 9.6607 | 8.2259 | 8.8719 | 9.5013 | 9.3620 | 10.5041 | 9.6057 | 8.7118 | 9.4492 | 9.7652 | 10.1770 | 8.7000 | 9.8920 | 9.4390 | 10.3546 | 8.7962 | 10.0259 | 9.0875 | 9.7664 | 7.6940 | 8.8828 | 9.5930 | 9.9977 | 9.3831 | 10.3364 | 9.1323 | 8.7566 | 9.7399 | 10.0099 | 9.7444 | 9.1189 | 9.0083 | 8.1796 | 10.4038 | 9.1923 | 9.7709 | 9.6962 | 10.0958 | 8.8630 | 7.6336 | 8.8077 | 8.5981 | 8.4425 | 9.8853 | 9.4760 | 9.7287 | 8.8882 | 9.5287 | 9.2013 | 9.0978 | 9.4316 | 9.8124 | 7.7796 | 9.4617 | 9.2914 | 9.4105 | 10.5849 | 8.6694 | 9.7140 | 9.3460 | 8.60395 |
| FUCA2 | 7.6301 | 8.9642 | 8.6309 | 8.8627 | 9.2936 | 8.2908 | 8.3179 | 8.7120 | 8.9429 | 9.1071 | 9.8461 | 8.9072 | 9.5534 | 8.8337 | 8.7893 | 8.3913 | 9.4626 | 9.0298 | 9.4713 | 8.9584 | 9.2984 | 8.5613 | 9.1216 | 8.5536 | 9.0762 | 8.9033 | 10.1280 | 9.1390 | 8.2937 | 9.6201 | 8.7738 | 9.2433 | 8.9197 | 8.7458 | 8.3691 | 8.9274 | 8.5536 | 9.3438 | 8.4097 | 8.8975 | 9.5206 | 9.1796 | 8.5198 | 8.3565 | 8.0039 | 8.5555 | 8.4261 | 8.8221 | 8.8106 | 8.1797 | 8.5265 | 8.2802 | 9.0250 | 8.6917 | 9.2221 | 8.8733 | 8.6657 | 9.7157 | 8.7806 | 9.2839 | 9.2839 | 8.9960 | 9.0781 | 9.4114 | 8.5256 | 8.8308 | 9.1825 | 8.1479 | 8.1653 | 8.7391 | 9.6384 | 8.5623 | 8.7922 | 9.0714 | 9.9012 | 9.5090 | 8.5478 | 8.4782 | 8.1160 | 8.2715 | 8.5130 | 8.9004 | 8.5381 | 9.0250 | 9.2965 | 8.5691 | 8.5575 | 9.3264 | 8.0735 | 8.7632 | 8.7420 | 9.3071 | 8.5652 | 9.1071 | 9.3312 | 8.5121 | 9.3177 | 9.0105 | 8.7777 | 8.3981 | 9.4220 | 8.5130 | 8.7420 | 8.3227 | 8.6927 | 9.0975 | 9.5273 | 9.0704 | 8.0165 | 9.0356 | 9.5727 | 8.9352 | 8.8540 | 8.2899 | 7.7798 | 8.7362 | 7.8223 | 8.5121 | 8.9091 | 7.9576 | 8.9835 | 9.0975 | 9.6906 | 9.5592 | 8.7787 | 8.8376 | 9.1371 | 8.4869 | 8.6792 | 8.7236 | 9.0907 | 9.1216 | 9.1728 | 8.3034 | 9.4559 | 9.2926 | 8.2348 | 9.8896 | 8.0213 | 8.5748 | 8.4570 | 8.7671 | 8.7545 | 8.7420 | 7.8020 | 8.2850 | 8.5014 | 9.2569 | 8.1063 | 9.0376 | 9.1834 | 8.7719 | 8.7574 | 8.5806 | 8.2744 | 8.8965 | 9.1342 | 9.1429 | 8.8502 | 8.6570 | 10.4470 | 8.1508 | 9.8452 | 8.0532 | 9.1661 | 9.7553 | 8.7101 | 8.4406 | 9.7177 | 9.1274 | 8.7410 | 8.5391 | 8.9516 | 8.2242 | 8.6164 | 8.9052 | 8.2754 | 8.8318 | 9.3940 | 10.0300 | 9.3805 | 8.7594 | 8.3469 | 8.1411 | 8.9960 | 8.4135 | 8.8985 | 9.3902 | 9.3969 | 8.4560 | 8.6570 | 9.3680 | 9.7186 | 8.2986 | 9.0260 | 8.8463 | 8.6618 | 8.9274 | 8.6251 | 8.3507 | 9.0752 | 9.1834 | 8.8279 | 9.6104 | 7.9875 | 8.7149 | 9.5901 | 8.6917 | 8.7391 | 8.9207 | 8.7603 | 9.9109 | 8.8299 | 8.9825 | 9.1535 | 9.4713 | 8.1817 | 9.0617 | 9.3853 | 8.6898 | 8.8569 | 9.0385 | 8.4744 | 8.3913 | 8.3160 | 8.8376 | 8.5497 | 9.2279 | 9.7418 | 8.0918 | 9.0752 | 8.3662 | 8.9255 | 7.8841 | 8.3749 | 9.1960 | 8.4647 | 8.9999 | 8.5449 | 8.6927 | 9.0260 | 7.9286 | 8.9149 | 8.1981 | 8.8927 | 9.1255 | 9.3100 | 9.1168 | 9.9408 | 8.4908 | 9.2337 | 9.0298 | 8.7536 | 8.4869 | 8.8598 | 8.4811 | 9.7611 | 9.2037 | 8.8241 | 9.6317 | 8.4638 | 8.6231 | 8.9951 | 8.2928 | 8.7613 | 8.8463 | 8.2280 | 8.4734 | 9.8094 | 9.8220 | 8.6096 | 8.4367 | 9.0086 | 8.5343 | 9.3013 | 8.8106 | 8.8714 | 8.2860 | 10.0130 | 8.9526 | 8.7120 | 9.3457 | 8.4406 | 8.7854 | 8.8820 | 9.4568 | 8.6405 | 8.7313 | 8.0677 | 8.4609 | 8.7091 | 8.9989 | 8.9931 | 9.0221 | 9.4346 | 8.7990 | 8.5903 | 8.4840 | 8.3604 | 8.5729 | 9.5785 | 8.6077 | 8.9584 | 8.2860 | 9.0588 | 8.1904 | 8.8434 | 9.0067 | 8.8270 | 9.1158 | 8.8521 | 9.2414 | 8.2126 | 8.7246 | 8.8318 | 8.7623 | 9.1226 | 8.8705 | 9.5109 | 8.6937 | 7.9846 | 8.5951 | 8.4889 | 8.6077 | 8.9815 | 8.4406 | 8.8791 | 9.3245 | 8.9390 | 8.6106 | 8.8598 | 8.5449 | 8.6859 | 8.5559 | 7.9649 | 8.3300 | 8.4302 | 9.0222 | 9.1097 | 8.8484 | 9.0289 | 7.8489 | 8.6761 | 9.1838 | 8.7993 | 9.5994 | 8.8182 | 9.8755 | 8.6838 | 9.2267 | 8.0943 | 9.1362 | 8.3985 | 8.4665 | 8.9839 | 7.7890 | 8.9195 | 9.1306 | 8.9629 | 8.8504 | 8.6117 | 8.8474 | 8.7221 | 9.1045 | 8.9599 | 8.5140 | 8.7201 | 8.0462 | 9.0212 | 8.0846 | 8.5125 | 9.6997 | 8.4174 | 8.4910 | 8.1480 | 9.4972 | 8.9118 | 8.2523 | 8.2456 | 8.7523 | 8.2523 | 8.1526 | 8.3571 | 9.3142 | 8.1705 | 8.5242 | 8.2880 | 8.8648 | 8.2354 | 8.2528 | 8.5498 | 9.3908 | 8.9721 | 9.1035 | 8.5887 | 8.5048 | 9.0268 | 8.6679 | 8.9057 | 8.5222 | 8.6899 | 8.3612 | 8.5698 | 8.8913 | 9.1603 | 8.5943 | 8.7047 | 8.6265 | 9.5662 | 8.9133 | 9.0979 | 8.6531 | 8.4164 | 8.7436 | 8.6925 | 7.8683 | 8.9251 | 8.6265 | 8.5815 | 10.0180 | 8.7681 | 8.6679 | 9.2881 | 8.5084 | 8.1868 | 8.8924 | 8.1117 | 8.3146 | 8.8116 | 8.5135 | 8.8233 | 10.1380 | 8.8305 | 8.8469 | 8.6107 | 8.8581 | 8.8745 | 8.5861 | 8.5989 | 9.8796 | 8.6229 | 9.1470 | 8.5416 | 7.7650 | 8.4537 | 7.9046 | 8.7993 | 8.3090 | 7.9271 | 8.7860 | 9.2293 | 8.3739 | 8.2354 | 8.7467 | 8.8412 | 7.6004 | 8.1076 | 9.4384 | 9.0601 | 8.8821 | 8.1883 | 9.1633 | 8.4210 | 9.7027 | 8.4373 | 9.3955 | 9.6531 | 8.4164 | 8.6935 | 8.9409 | 8.7247 | 8.9967 | 8.5130 | 8.4547 | 8.6485 | 9.3004 | 8.7932 | 9.6879 | 9.1909 | 8.8458 | 9.5442 | 8.9026 | 8.3474 | 9.0100 | 8.5800 | 9.0529 | 9.3213 | 7.9751 | 8.6362 | 9.0698 | 8.6275 | 8.6505 | 8.7354 | 8.9767 | 9.1388 | 9.7452 | 9.1035 | 8.0805 | 8.5595 | 8.0554 | 8.2461 | 8.8085 | 9.0749 | 8.9082 | 7.8954 | 8.5856 | 8.5585 | 8.8719 | 8.9379 | 8.4670 | 8.8709 | 8.4481 | 8.7794 | 8.6270 | 9.0585 | 7.8299 | 9.1086 | 8.6935 | 8.5268 | 9.0713 | 8.8325 | 9.1725 | 8.5682 | 8.7328 | 8.9762 | 8.9133 | 8.9430 | 8.7328 | 8.8525 | 8.5360 | 9.3816 | 8.8428 | 8.6285 | 8.6086 | 9.6332 | 8.4900 | 8.6270 | 9.0314 | 9.0616 | 8.7937 | 8.8285 | 8.9900 | 8.7467 | 8.6163 | 8.6188 | 8.4721 | 8.4189 | 8.9000 | 8.2369 | 8.6413 | 8.2114 | 9.3776 | 8.4005 | 9.1439 | 8.2860 | 8.8131 | 8.7001 | 8.9992 | 8.5744 | 8.6654 | 8.8959 | 8.7978 | 9.0161 | 8.7185 | 9.5790 | 8.4936 | 8.8397 | 9.3607 | 8.8458 | 8.6239 | 9.1183 | 8.3888 | 9.6700 | 8.6142 | 8.7155 | 9.0948 | 8.9246 | 9.1245 | 8.1249 | 8.7937 | 8.3842 | 8.7058 | 8.7845 | 8.0278 | 8.4752 | 8.6730 | 9.5110 | 7.9445 | 9.1040 | 8.6751 | 8.4026 | 8.5616 | 8.7139 | 8.9368 | 8.9011 | 9.4410 | 8.6193 | 8.3750 | 8.7201 | 8.6720 | 9.2998 | 8.8510 | 8.2400 | 9.1526 | 9.1444 | 8.7022 | 8.8085 | 8.5033 | 8.1081 | 8.4542 | 8.9532 | 8.3039 | 8.2047 | 8.7426 | 8.9251 | 8.4614 | 8.6597 | 9.3535 | 8.2410 | 8.6725 | 8.8653 | 8.9374 | 8.3059 | 8.3606 | 8.2395 | 8.3765 | 8.8014 | 8.9859 | 9.5964 | 8.9046 | 8.7845 | 8.5784 | 8.7032 | 8.3785 | 9.5294 | 8.6490 | 8.6352 | 8.7988 | 8.5171 | 9.2533 | 9.4399 | 9.2088 | 8.3356 | 8.4491 | 8.1705 | 9.7758 | 9.2998 | 8.8310 | 8.7083 | 8.5554 | 8.2574 | 8.7763 | 9.1245 | 8.3535 | 9.5090 | 9.1229 | 8.1275 | 8.3417 | 8.8407 | 9.2421 | 8.9982 | 8.6050 | 9.2963 | 8.7860 | 9.2298 | 8.7282 | 9.0161 | 8.6204 | 8.3514 | 8.2773 | 8.9435 | 8.7037 | 8.8688 | 9.1475 | 9.4537 | 8.9491 | 9.2707 | 8.8392 | 8.8474 | 8.5007 | 8.9338 | 9.1204 | 8.2032 | 8.9343 | 9.2206 | 7.7604 | 8.5503 | 9.4885 | 8.9737 | 9.0232 | 8.1091 | 9.1526 | 8.4368 | 9.5187 | 9.8653 | 8.6306 | 7.8872 | 8.4174 | 8.6623 | 8.7339 | 8.7298 | 8.3801 | 8.1065 | 8.3862 | 8.7497 | 8.8044 | 8.7778 | 8.7247 | 8.8750 | 8.6756 | 9.1097 | 8.7993 | 8.9057 | 8.6127 | 8.6551 | 8.7088 | 8.2257 | 8.4460 | 8.9701 | 8.8111 | 8.3673 | 9.6127 | 8.5232 | 8.5764 | 8.4695 | 9.1112 | 8.7252 | 9.6005 | 8.6061 | 8.8392 | 8.8755 | 8.7727 | 8.8136 | 8.6101 | 9.0059 | 8.7901 | 8.4174 | 8.9767 | 9.2564 | 9.0115 | 8.6919 | 8.5309 | 8.5534 | 8.6122 | 8.4194 | 9.2267 | 9.2738 | 8.5554 | 8.3964 | 8.2952 | 8.3167 | 9.9543 | 9.5529 | 8.5457 | 9.2400 | 9.0774 | 10.2610 | 10.1000 | 8.7528 | 8.7523 | 9.0994 | 9.1153 | 8.5922 | 9.0253 | 8.6597 | 9.3985 | 9.2707 | 9.8571 | 9.4849 | 9.2431 | 9.1429 | 9.1981 | 9.0473 | 10.9790 | 9.2196 | 9.1664 | 8.6142 | 8.5273 | 8.9946 | 8.8233 | 9.1209 | 8.7150 | 9.6179 | 10.4390 | 9.0038 | 9.0524 | 8.9077 | 9.0284 | 8.3157 | 8.7916 | 9.4231 | 9.3760 | 8.4675 | 9.8106 | 8.9629 | 9.4486 | 9.1071 | 8.8939 | 8.8883 | 9.3300 | 9.1408 | 8.7513 | 10.3750 | 8.6838 | 8.8458 | 9.1301 | 8.9087 | 8.6158 | 8.6822 | 8.8755 | 8.7073 | 8.9348 | 9.0739 | 9.2293 | 8.9466 | 8.6321 | 8.9609 | 8.3422 | 9.2186 | 8.9527 | 8.7252 | 8.5784 | 9.2554 | 9.1071 | 8.5442 | 9.2012 | 9.5994 | 10.2310 | 9.2794 | 9.0693 | 8.9793 | 8.8821 | 8.3872 | 8.9179 | 8.9241 | 9.7119 | 9.0882 | 8.9772 | 8.9568 | 10.4710 | 8.7513 | 8.3560 | 9.0345 | 9.6035 | 9.6859 | 8.9241 | 9.5698 | 9.1434 | 9.4195 | 9.3111 | 8.6526 | 9.4026 | 9.3975 | 8.7610 | 8.1224 | 8.8607 | 8.6853 | 8.5294 | 9.4185 | 9.5330 | 8.6444 | 9.6260 | 9.7523 | 9.7717 | 9.0989 | 8.4583 | 8.7272 | 9.0074 | 9.6603 | 9.5795 | 8.5682 | 9.7160 | 9.2329 | 10.8860 | 8.8637 | 8.8167 | 8.7661 | 9.2277 | 9.1315 | 9.1591 | 7.5235 | 9.1612 | 9.7103 | 8.6893 | 8.9822 | 9.2200 | 8.2153 | 8.8779 | 9.2461 | 9.8085 | 9.4690 | 9.2302 | 9.1709 | 8.3508 | 9.0145 | 9.3846 | 9.6715 | 8.1539 | 9.4874 | 9.6756 | 9.3841 | 9.6377 | 8.5216 | 9.3381 | 9.4153 | 8.8692 | 8.8329 | 10.0007 | 9.8223 | 9.0702 | 9.5564 | 8.1923 | 8.6703 | 8.8744 | 9.4434 | 9.8596 | 9.0267 | 7.9965 | 9.5605 | 10.4711 | 8.9705 | 9.0446 | 9.6526 | 8.5942 | 9.2389 | 9.1888 | 8.5896 | 8.6356 | 9.1274 | 8.8626 | 9.3136 | 9.7154 | 8.2526 | 8.3856 | 9.3110 | 9.0477 | 8.8723 | 8.4704 | 9.1142 | 8.8309 | 9.4133 | 10.0100 | 8.8667 | 9.8750 | 9.2706 | 9.8796 | 9.6127 | 9.1832 | 8.8774 | 9.5580 | 10.4369 | 8.0665 | 9.3054 | 9.3131 | 8.2797 | 8.6371 | 9.8387 | 8.7752 | 8.7522 | 9.0983 | 9.2926 | 8.5906 | 8.6361 | 9.0267 | 8.8672 | 8.9229 | 8.6857 | 9.5743 | 8.6898 | 8.7092 | 9.0482 | 8.4321 | 8.6944 | 9.3422 | 8.4014 | 9.3780 | 8.9505 | 8.1028 | 9.0185 | 8.5614 | 8.6289 | 9.2706 | 8.4234 | 8.3298 | 8.3815 | 9.7676 | 9.68960 |
| GCLC | 8.8570 | 8.6128 | 8.5548 | 7.7268 | 8.5620 | 8.8988 | 8.7354 | 9.7240 | 8.8308 | 9.2774 | 9.0616 | 9.1999 | 9.5483 | 9.4987 | 8.6351 | 8.3284 | 8.6568 | 9.1302 | 9.1084 | 9.4045 | 8.6038 | 8.8519 | 9.3850 | 9.1129 | 8.6373 | 9.2417 | 8.7020 | 8.4115 | 9.3030 | 7.8601 | 9.0722 | 9.5617 | 8.6997 | 8.4003 | 8.0535 | 8.1466 | 9.5818 | 8.8079 | 8.5040 | 8.6473 | 8.3245 | 9.0298 | 9.0120 | 8.7343 | 9.6794 | 8.7644 | 8.9590 | 9.9219 | 8.6345 | 9.9370 | 9.3727 | 9.0934 | 8.6707 | 8.7315 | 8.6613 | 9.0923 | 9.1898 | 8.9278 | 8.6986 | 8.9412 | 9.7647 | 9.2974 | 7.9532 | 8.7321 | 9.2489 | 8.9027 | 7.5155 | 9.1714 | 8.7878 | 7.8316 | 8.4628 | 8.5999 | 8.5040 | 8.4873 | 9.0376 | 8.5280 | 9.1073 | 8.4929 | 9.9514 | 8.7917 | 8.9055 | 8.5944 | 8.3864 | 8.0976 | 8.5704 | 8.6819 | 8.7990 | 9.3515 | 8.8848 | 9.4117 | 9.9442 | 8.6367 | 7.9571 | 9.1357 | 8.6429 | 9.1553 | 8.9233 | 9.3465 | 8.6457 | 8.6936 | 8.7332 | 8.7906 | 8.4951 | 9.0398 | 8.5615 | 8.9451 | 8.4946 | 8.2174 | 8.9317 | 8.6222 | 9.1686 | 8.8988 | 9.4023 | 8.5821 | 9.4496 | 8.1818 | 8.6802 | 8.6094 | 8.7042 | 8.2498 | 8.7544 | 8.9172 | 9.4352 | 9.9425 | 9.2144 | 8.9434 | 9.6281 | 8.7114 | 8.5932 | 9.0231 | 9.0025 | 9.5338 | 8.1076 | 8.8860 | 9.5589 | 8.4003 | 8.7053 | 8.1327 | 8.9690 | 9.3225 | 8.9462 | 8.6685 | 8.5224 | 9.2250 | 9.3030 | 8.6206 | 8.9802 | 9.0136 | 8.8302 | 8.3574 | 9.1441 | 8.2871 | 9.3047 | 9.2852 | 10.1350 | 9.8857 | 8.7048 | 9.3281 | 9.0025 | 8.8982 | 9.7429 | 8.7962 | 9.2355 | 8.6529 | 8.8112 | 8.9289 | 9.0884 | 8.5548 | 8.2437 | 8.9529 | 7.9766 | 8.2531 | 8.4845 | 8.8915 | 9.1129 | 8.5732 | 8.5280 | 8.5748 | 8.9244 | 9.0337 | 8.0808 | 9.1452 | 8.7722 | 9.5004 | 8.6847 | 9.4703 | 9.1659 | 10.1170 | 8.0926 | 8.9997 | 9.9074 | 8.6089 | 9.0521 | 8.2604 | 8.3920 | 8.8642 | 8.6875 | 9.8104 | 9.7262 | 9.2417 | 9.5160 | 9.1001 | 8.8397 | 9.1341 | 8.6434 | 8.4555 | 9.0404 | 8.1951 | 9.2250 | 9.2422 | 8.4578 | 8.6178 | 9.0075 | 10.3280 | 9.1882 | 8.5358 | 9.9849 | 9.2578 | 8.1901 | 8.5035 | 9.3147 | 8.5074 | 8.7148 | 8.5787 | 9.4931 | 8.8319 | 8.6373 | 9.4686 | 8.6674 | 11.0860 | 8.6417 | 8.9456 | 8.6055 | 8.8664 | 8.6233 | 9.1586 | 8.7449 | 9.2919 | 8.8062 | 8.1723 | 9.0649 | 9.4708 | 8.2353 | 9.2105 | 9.1335 | 8.7053 | 9.1207 | 9.2216 | 9.5584 | 8.6624 | 8.4884 | 9.0421 | 9.7780 | 8.1405 | 8.6066 | 9.1095 | 10.1150 | 8.5899 | 8.7416 | 9.7167 | 8.8670 | 8.5905 | 8.4321 | 8.7549 | 8.3836 | 8.7928 | 8.5163 | 9.3504 | 8.2883 | 8.2230 | 8.9846 | 9.8160 | 8.5637 | 8.4873 | 8.7075 | 9.1831 | 8.7114 | 9.0761 | 8.6250 | 9.6504 | 9.3515 | 8.5905 | 8.4020 | 8.7995 | 9.2528 | 8.4778 | 8.6529 | 9.3833 | 8.8224 | 9.3978 | 8.9289 | 8.9880 | 8.4979 | 9.2902 | 8.6222 | 8.6824 | 8.7159 | 8.6362 | 8.7020 | 9.1357 | 9.2171 | 8.3914 | 7.8746 | 8.9635 | 8.5670 | 9.4491 | 8.8135 | 9.6704 | 9.0192 | 9.2500 | 9.2539 | 8.9517 | 9.5991 | 8.7315 | 8.0669 | 8.9166 | 9.1224 | 9.5684 | 9.2199 | 9.1369 | 7.7101 | 8.5314 | 9.0844 | 9.3275 | 8.9679 | 8.6284 | 8.6847 | 9.0549 | 10.0140 | 8.6663 | 9.3922 | 8.6116 | 8.3663 | 8.4165 | 8.7378 | 9.8844 | 8.7131 | 9.1159 | 9.2694 | 9.1898 | 8.7662 | 8.4791 | 8.3085 | 8.9510 | 9.5972 | 8.3009 | 8.5738 | 8.4032 | 8.6420 | 9.2836 | 9.1585 | 8.9491 | 9.7176 | 8.8534 | 9.1339 | 9.2324 | 9.1822 | 10.0650 | 8.3606 | 9.8105 | 7.9835 | 8.9851 | 7.9389 | 8.2014 | 8.2602 | 8.3786 | 9.4134 | 8.9074 | 8.7359 | 9.1206 | 9.3613 | 8.6856 | 8.4781 | 9.1879 | 8.6439 | 8.7671 | 8.6553 | 8.4582 | 8.7415 | 9.0353 | 8.5321 | 8.7652 | 8.8723 | 8.6619 | 8.8941 | 9.0315 | 7.7579 | 9.1718 | 8.5624 | 9.0912 | 9.0097 | 8.8060 | 9.1727 | 9.3452 | 8.5738 | 8.8136 | 8.5947 | 9.0220 | 9.6010 | 8.4772 | 9.5423 | 9.3272 | 8.4895 | 8.6999 | 8.1559 | 8.6818 | 8.1967 | 9.4523 | 9.2040 | 8.8136 | 8.5852 | 8.5776 | 10.2890 | 9.1130 | 8.7861 | 8.8856 | 9.5982 | 9.5025 | 8.9633 | 9.1737 | 9.3385 | 9.2788 | 8.8069 | 8.2876 | 8.7160 | 8.8344 | 8.6250 | 8.5274 | 8.5425 | 9.0277 | 10.4640 | 8.9443 | 9.1358 | 8.6515 | 9.5963 | 9.6228 | 8.8012 | 8.5416 | 8.3881 | 9.5015 | 9.8124 | 8.9292 | 9.2722 | 8.8098 | 9.5698 | 8.7994 | 9.0173 | 8.8126 | 9.1708 | 9.1509 | 9.0780 | 8.8894 | 9.8133 | 9.1187 | 8.6638 | 9.1007 | 9.0344 | 9.4674 | 9.0069 | 9.2011 | 9.2997 | 9.3186 | 9.0761 | 9.3878 | 9.2390 | 7.1884 | 9.8114 | 8.6771 | 8.6316 | 8.6961 | 9.3177 | 8.8202 | 9.7678 | 8.5141 | 9.8342 | 8.8998 | 8.6022 | 8.6250 | 8.8562 | 9.0723 | 8.7889 | 10.1320 | 10.2260 | 9.1178 | 8.9102 | 8.4497 | 8.5312 | 9.3945 | 9.0059 | 8.3549 | 9.6740 | 8.3672 | 9.3774 | 8.7510 | 9.6058 | 8.1540 | 9.2665 | 8.5549 | 9.3310 | 9.1073 | 9.1433 | 8.7368 | 8.7321 | 9.5385 | 9.6901 | 9.1064 | 9.4011 | 8.3142 | 9.3120 | 9.5375 | 9.2457 | 9.1462 | 8.8240 | 8.9785 | 8.7643 | 9.0912 | 7.3031 | 8.5312 | 8.6866 | 8.8875 | 8.7662 | 9.3774 | 9.7394 | 8.9699 | 9.0078 | 8.5899 | 8.9083 | 8.9083 | 8.7425 | 9.3063 | 9.1054 | 10.2160 | 8.0176 | 9.1405 | 9.1149 | 9.2608 | 8.7283 | 8.5084 | 9.9327 | 8.7520 | 8.5729 | 8.7491 | 8.7785 | 8.8780 | 8.7908 | 10.5780 | 8.8600 | 9.4940 | 9.3035 | 8.7880 | 8.7169 | 8.8382 | 9.6096 | 8.0782 | 8.6847 | 8.0394 | 9.1234 | 9.1263 | 9.1812 | 8.1408 | 8.9500 | 9.5546 | 9.3319 | 7.7210 | 8.1332 | 8.3104 | 8.6051 | 10.2220 | 9.3802 | 8.8069 | 9.0258 | 8.7131 | 8.8107 | 9.2154 | 8.6648 | 8.9188 | 8.4696 | 8.5985 | 9.3935 | 9.1680 | 9.9962 | 9.4712 | 9.4409 | 8.8932 | 8.9273 | 8.9927 | 9.5195 | 8.2820 | 9.5167 | 8.2308 | 9.1348 | 9.0088 | 9.3442 | 8.7084 | 9.9033 | 8.6004 | 8.7444 | 8.3739 | 9.5366 | 9.0069 | 8.2516 | 8.3521 | 9.0258 | 10.1080 | 9.1812 | 9.1519 | 9.7394 | 8.5388 | 8.2772 | 8.6117 | 9.1291 | 9.1651 | 8.6762 | 8.7975 | 8.9965 | 9.4712 | 10.1970 | 8.5681 | 8.7586 | 9.3423 | 8.8628 | 9.0950 | 9.5527 | 8.9766 | 8.8733 | 8.5852 | 8.9737 | 8.4828 | 9.0609 | 8.8543 | 9.0855 | 9.2447 | 9.1433 | 9.2826 | 8.7662 | 9.0505 | 8.8249 | 8.8771 | 9.0467 | 9.6115 | 8.5009 | 8.4971 | 8.7633 | 8.8600 | 9.5470 | 9.6787 | 9.3670 | 9.6209 | 8.7757 | 9.6456 | 9.3215 | 8.8704 | 8.8922 | 9.4011 | 9.2002 | 8.8695 | 8.9131 | 8.6060 | 9.0618 | 9.0088 | 8.1152 | 8.7652 | 8.5264 | 8.9311 | 8.7633 | 9.0107 | 8.8003 | 9.2135 | 8.1237 | 8.1351 | 9.2239 | 8.3037 | 9.3111 | 8.9481 | 8.6269 | 9.3859 | 9.2845 | 9.3253 | 9.2248 | 8.6127 | 8.5435 | 8.7302 | 8.7728 | 8.9680 | 8.5568 | 9.2182 | 8.9083 | 8.9747 | 8.3454 | 8.5274 | 8.8979 | 9.3414 | 8.8827 | 8.5274 | 8.6345 | 8.5463 | 8.8496 | 9.6674 | 8.8164 | 8.4753 | 8.9728 | 8.9197 | 8.4326 | 8.3075 | 8.8818 | 8.7937 | 9.5053 | 9.3338 | 9.2580 | 8.7918 | 8.4023 | 8.5369 | 8.6563 | 9.2059 | 9.1386 | 9.0325 | 9.2969 | 8.7387 | 8.7918 | 8.9349 | 8.9718 | 9.2343 | 9.1689 | 10.1100 | 8.8041 | 8.4781 | 8.8600 | 8.3530 | 8.3540 | 7.9711 | 9.6342 | 8.5492 | 8.6648 | 9.1083 | 8.8174 | 10.5660 | 9.2874 | 8.5871 | 8.2943 | 8.7216 | 9.2646 | 9.1149 | 9.2987 | 8.6136 | 8.5160 | 8.9339 | 8.6288 | 9.6607 | 10.1320 | 9.9469 | 8.9244 | 9.1339 | 8.4402 | 8.8534 | 8.5141 | 8.3360 | 9.3196 | 9.3897 | 8.7908 | 8.3312 | 8.3322 | 8.8354 | 8.8022 | 8.2782 | 9.0609 | 8.0413 | 9.0543 | 9.8199 | 8.6856 | 8.8685 | 8.0308 | 8.4961 | 8.8117 | 8.2715 | 9.8588 | 8.4421 | 8.0005 | 8.1379 | 8.9813 | 9.3907 | 9.7669 | 8.8060 | 9.0107 | 9.0988 | 8.7112 | 8.6449 | 9.1035 | 8.1891 | 9.0476 | 7.7503 | 8.7908 | 8.6894 | 8.1085 | 8.8562 | 9.0002 | 8.6430 | 8.2763 | 8.6108 | 9.3613 | 8.8676 | 8.1474 | 9.5764 | 8.7169 | 9.0325 | 9.4598 | 10.6450 | 9.2210 | 8.5634 | 8.3786 | 8.8107 | 8.4942 | 8.8989 | 8.3928 | 8.2365 | 8.6638 | 9.0353 | 8.8695 | 8.3559 | 8.6999 | 8.8193 | 9.4921 | 7.7011 | 8.5416 | 8.8657 | 8.0716 | 8.5767 | 8.4525 | 8.6146 | 8.9434 | 9.3205 | 8.4629 | 9.2343 | 8.7614 | 8.7131 | 8.8344 | 9.3082 | 8.9349 | 9.2618 | 7.9673 | 8.7273 | 8.0261 | 8.5075 | 7.8366 | 8.8136 | 7.7210 | 8.9131 | 8.3369 | 8.2365 | 8.0649 | 9.2732 | 8.5407 | 7.9238 | 8.9263 | 9.1206 | 9.0287 | 8.3037 | 8.6591 | 8.2791 | 8.9889 | 8.5624 | 8.4923 | 8.7596 | 8.2118 | 8.4468 | 8.7529 | 8.5359 | 8.5530 | 8.2308 | 8.3985 | 8.3644 | 9.3385 | 8.3426 | 8.6610 | 9.8957 | 8.6544 | 8.4478 | 8.6695 | 8.7463 | 8.8429 | 7.6489 | 9.3698 | 8.6923 | 7.5997 | 8.5340 | 9.3689 | 9.1632 | 8.4544 | 8.2696 | 8.5075 | 8.7254 | 9.2466 | 9.0107 | 8.4762 | 9.8844 | 8.2943 | 9.8521 | 8.8969 | 9.6550 | 8.3862 | 9.6484 | 8.8685 | 8.2592 | 8.2639 | 8.3502 | 9.0230 | 9.4295 | 8.8003 | 8.6487 | 8.7567 | 8.4137 | 8.7065 | 8.5710 | 8.1019 | 8.5103 | 8.8742 | 8.8126 | 8.8230 | 10.8016 | 8.7216 | 7.8773 | 8.6155 | 8.7197 | 8.5226 | 9.0201 | 8.7017 | 9.1774 | 8.9851 | 10.0142 | 8.4743 | 8.5994 | 8.7103 | 9.0675 | 8.8657 | 7.6366 | 9.7015 | 9.3992 | 8.6885 | 8.6866 | 8.1806 | 9.0429 | 8.3587 | 8.2194 | 9.5631 | 9.5830 | 8.4383 | 8.5785 | 8.4809 | 8.4800 | 9.3509 | 8.5624 | 8.5672 | 9.1215 | 9.9905 | 10.1648 | 8.6506 | 9.3726 | 9.3509 | 8.8050 | 9.7223 | 8.7463 | 8.1682 | 9.2172 | 9.4181 | 8.9661 | 9.4077 | 9.6844 | 9.3518 | 8.3938 | 9.4323 | 8.2706 | 8.9064 | 9.0457 | 9.7811 | 9.2807 | 9.2457 | 8.8420 | 9.0959 | 8.5748 | 8.7292 | 9.5792 | 8.1881 | 8.6506 | 8.7472 | 9.4665 | 9.1917 | 9.1121 | 7.98640 |
| NFYA | 7.5652 | 7.6406 | 8.0892 | 8.5125 | 8.2673 | 8.0805 | 7.7398 | 7.5644 | 8.2209 | 7.9051 | 8.3292 | 7.8130 | 8.4661 | 8.1605 | 7.2901 | 7.6342 | 7.8300 | 8.6415 | 8.2575 | 7.9968 | 8.1488 | 8.7864 | 8.5363 | 8.8060 | 8.1496 | 8.4612 | 9.4255 | 8.5087 | 8.5495 | 8.4789 | 8.1794 | 8.3201 | 8.7242 | 8.0922 | 7.7708 | 7.6263 | 8.1854 | 8.0145 | 7.9108 | 7.9613 | 7.7840 | 8.3435 | 8.4020 | 8.3873 | 8.1658 | 7.9523 | 7.2313 | 8.5103 | 8.2405 | 9.6376 | 7.6489 | 8.8132 | 8.3009 | 8.2801 | 7.6131 | 8.8755 | 8.4521 | 9.2603 | 7.7161 | 8.6812 | 9.7224 | 8.2220 | 8.6680 | 8.8898 | 8.3616 | 7.8719 | 8.4095 | 7.9202 | 7.8862 | 8.1439 | 8.0402 | 7.7595 | 8.1545 | 7.9104 | 8.3684 | 8.0198 | 8.0737 | 7.8991 | 8.0545 | 8.1277 | 8.5235 | 8.1349 | 8.1775 | 7.5652 | 7.8327 | 7.8259 | 8.3703 | 7.6950 | 7.8904 | 8.2816 | 8.8264 | 7.9175 | 7.5048 | 8.1515 | 8.2548 | 8.0345 | 8.1496 | 8.6849 | 7.3607 | 8.1598 | 7.9070 | 8.9226 | 7.3015 | 7.7866 | 7.8568 | 8.4122 | 8.4616 | 8.0722 | 9.2724 | 7.9062 | 8.1450 | 9.6198 | 7.8534 | 7.8900 | 7.6731 | 7.8828 | 7.4671 | 8.2745 | 8.7494 | 8.3801 | 7.7538 | 8.0213 | 8.1051 | 8.2341 | 7.8210 | 7.5278 | 8.6238 | 8.3110 | 7.7255 | 8.6649 | 8.0096 | 7.0185 | 8.3522 | 8.5404 | 8.2911 | 8.4589 | 9.0581 | 7.3286 | 7.8564 | 9.1667 | 7.5652 | 8.1073 | 7.9266 | 9.2746 | 7.9032 | 8.9185 | 8.5518 | 7.9772 | 7.9032 | 8.8396 | 8.9430 | 7.9145 | 7.5761 | 7.9168 | 8.8241 | 8.1677 | 8.3559 | 7.6052 | 9.1497 | 8.6657 | 7.6806 | 8.7359 | 8.3586 | 8.2658 | 9.2920 | 7.4663 | 8.5291 | 6.9736 | 7.9877 | 8.4295 | 8.4842 | 8.0088 | 7.6014 | 9.3523 | 7.7195 | 7.9692 | 8.6359 | 7.4135 | 8.0590 | 8.8864 | 8.0322 | 7.7738 | 7.3230 | 8.1605 | 7.6399 | 7.6697 | 8.0405 | 6.8608 | 7.4199 | 7.5471 | 8.2413 | 7.6791 | 7.8406 | 8.3990 | 8.4348 | 8.1277 | 7.3765 | 7.8549 | 8.5480 | 8.8053 | 8.3590 | 7.5980 | 8.2567 | 8.2126 | 8.3458 | 8.3107 | 8.3873 | 8.5208 | 7.6599 | 8.5265 | 7.8078 | 8.2858 | 7.8225 | 7.6531 | 8.1054 | 7.4920 | 8.8109 | 8.0088 | 8.0515 | 9.6994 | 9.3893 | 9.0113 | 9.1184 | 7.7368 | 7.3573 | 7.8572 | 9.1897 | 9.3674 | 8.2590 | 8.2563 | 7.9900 | 8.1069 | 9.1433 | 9.2320 | 7.5463 | 7.9232 | 8.0768 | 7.8972 | 8.5997 | 8.4144 | 8.8208 | 7.8942 | 8.9886 | 8.2865 | 7.6923 | 7.7508 | 7.8610 | 8.4091 | 7.8228 | 7.3430 | 7.7044 | 8.2031 | 7.9409 | 8.6483 | 9.0679 | 7.6029 | 7.7029 | 7.6927 | 7.8244 | 8.3363 | 7.9402 | 8.3597 | 8.0881 | 8.4963 | 7.2732 | 8.9954 | 8.1315 | 7.5501 | 7.7368 | 8.3665 | 8.4623 | 7.8900 | 8.4853 | 8.1217 | 8.6125 | 7.9666 | 7.4497 | 7.5984 | 8.9162 | 7.9723 | 8.0141 | 7.9413 | 8.4329 | 8.6944 | 7.7289 | 7.3958 | 8.5721 | 7.8266 | 8.2745 | 8.4733 | 9.0958 | 8.4548 | 8.7596 | 7.7847 | 7.7938 | 7.9319 | 9.0045 | 8.2488 | 8.2152 | 8.0866 | 8.7928 | 8.1835 | 7.9036 | 7.6991 | 7.6297 | 7.9726 | 7.3086 | 8.7181 | 8.3507 | 9.1448 | 7.3622 | 7.9704 | 8.4887 | 8.6966 | 8.3197 | 8.3514 | 7.9904 | 7.7595 | 8.3160 | 9.3414 | 9.4455 | 9.4350 | 7.5501 | 8.5008 | 8.9935 | 7.7644 | 7.9077 | 7.7470 | 8.9087 | 7.7289 | 9.2433 | 7.4625 | 8.0779 | 8.1981 | 8.1143 | 7.3461 | 7.7611 | 8.1193 | 7.6487 | 9.0369 | 7.3992 | 7.2880 | 8.1077 | 10.5250 | 8.3874 | 7.8675 | 7.4243 | 7.8701 | 8.5127 | 7.6013 | 7.8371 | 7.5448 | 9.2551 | 7.9988 | 7.9262 | 8.1805 | 7.8569 | 8.0581 | 8.1168 | 8.1275 | 7.8110 | 7.9049 | 8.3723 | 7.3147 | 7.2752 | 7.7147 | 8.6254 | 8.6495 | 8.1645 | 8.2898 | 8.3827 | 7.4428 | 7.5263 | 8.1567 | 7.8424 | 7.9834 | 7.6202 | 8.1680 | 7.9595 | 9.5668 | 8.6348 | 7.6594 | 8.6448 | 7.5530 | 8.7880 | 7.9893 | 7.2805 | 9.2733 | 7.6883 | 7.8845 | 8.3588 | 8.3092 | 7.8424 | 8.4706 | 8.0079 | 8.0286 | 7.8892 | 9.6500 | 8.2386 | 7.5247 | 8.2273 | 8.2267 | 7.8763 | 8.3748 | 8.3893 | 7.9856 | 8.0616 | 8.7475 | 7.8518 | 7.8657 | 8.4464 | 8.3648 | 7.8437 | 7.5665 | 8.3359 | 9.0096 | 8.8677 | 8.5403 | 8.0543 | 8.4904 | 8.6436 | 8.3237 | 8.0342 | 7.9404 | 8.1884 | 8.6542 | 7.4302 | 7.8867 | 8.2345 | 7.5304 | 7.4805 | 8.5070 | 7.8644 | 7.8104 | 8.1604 | 9.4026 | 9.1509 | 8.5456 | 7.9435 | 7.2146 | 8.0333 | 8.8567 | 8.0798 | 7.9718 | 8.5415 | 8.9660 | 8.2998 | 8.3435 | 7.5420 | 8.0389 | 8.1981 | 8.3560 | 8.4307 | 7.7614 | 8.3161 | 8.2242 | 8.4336 | 8.6954 | 8.1033 | 8.4084 | 9.4921 | 9.1785 | 7.7018 | 7.7143 | 7.9991 | 7.7850 | 8.9468 | 8.1881 | 7.8230 | 8.1648 | 8.3067 | 8.8112 | 7.3841 | 8.3861 | 8.2524 | 7.9793 | 7.4824 | 8.0738 | 7.9699 | 8.0233 | 7.8776 | 8.8837 | 7.6582 | 8.1673 | 8.2276 | 7.4302 | 9.0554 | 8.8966 | 8.5613 | 7.9297 | 8.0047 | 8.0402 | 8.1199 | 8.3278 | 8.1786 | 7.8528 | 7.4949 | 8.4759 | 8.3130 | 7.7991 | 8.1504 | 8.3485 | 8.3312 | 8.5419 | 8.2628 | 7.8591 | 9.1568 | 8.5626 | 7.9131 | 8.0176 | 7.7834 | 7.8854 | 8.0101 | 8.5506 | 8.8552 | 8.5139 | 8.1567 | 7.7162 | 8.6583 | 7.7627 | 7.6679 | 7.6130 | 7.8569 | 8.6345 | 8.0634 | 8.1278 | 7.7614 | 8.8159 | 8.4405 | 8.1036 | 8.3083 | 7.9369 | 7.9893 | 8.0989 | 7.8022 | 8.7754 | 8.7239 | 7.6808 | 8.1542 | 9.2567 | 7.5213 | 8.2863 | 8.7519 | 8.4923 | 8.3061 | 7.8176 | 8.4163 | 8.0465 | 8.5572 | 8.1538 | 8.6429 | 8.6134 | 7.9379 | 8.9688 | 8.5133 | 7.6528 | 8.0882 | 7.6845 | 11.3500 | 8.3315 | 8.0528 | 8.1011 | 8.1837 | 8.9766 | 7.6657 | 7.6271 | 7.7580 | 9.5364 | 7.8977 | 8.4781 | 7.7235 | 7.9536 | 8.8319 | 8.0176 | 8.4204 | 7.5502 | 7.3197 | 7.8503 | 8.0145 | 7.8396 | 7.6892 | 8.4549 | 8.0289 | 8.8599 | 7.9667 | 7.7555 | 7.8559 | 7.5464 | 8.0870 | 7.7087 | 8.0697 | 8.2973 | 8.0725 | 7.7316 | 8.2816 | 8.8683 | 7.5316 | 8.7943 | 8.2050 | 7.6092 | 7.7941 | 8.6464 | 8.6486 | 8.4988 | 8.2769 | 8.0251 | 8.3585 | 8.0666 | 7.6877 | 8.1096 | 7.9197 | 7.6773 | 7.8625 | 8.8803 | 9.4168 | 8.4044 | 7.9423 | 8.2408 | 8.3538 | 8.5130 | 7.4955 | 7.9354 | 9.0784 | 8.1174 | 8.2609 | 7.7592 | 7.8644 | 8.1645 | 8.9474 | 8.2926 | 8.0998 | 8.1818 | 8.4634 | 8.3281 | 8.5036 | 8.0942 | 7.9460 | 8.2016 | 7.7081 | 8.3196 | 8.6517 | 7.9589 | 7.7498 | 7.5960 | 8.1356 | 7.1148 | 7.8569 | 8.1196 | 8.2907 | 8.3403 | 8.0273 | 8.0182 | 8.6511 | 8.4530 | 7.8214 | 7.9344 | 9.9253 | 8.4317 | 7.8264 | 8.3683 | 7.9909 | 7.6484 | 9.3813 | 8.2119 | 7.5888 | 8.2543 | 7.7850 | 8.1799 | 8.7980 | 8.0054 | 8.5105 | 7.7388 | 8.0785 | 7.6516 | 7.6820 | 7.9043 | 7.8603 | 7.9445 | 8.4012 | 8.5635 | 8.0455 | 7.9504 | 9.3377 | 8.5921 | 8.2471 | 8.6863 | 7.8044 | 8.7089 | 7.3141 | 8.2251 | 8.1306 | 8.1306 | 8.1586 | 7.4933 | 7.9137 | 8.6593 | 7.5991 | 8.2345 | 7.8261 | 8.3362 | 8.0515 | 8.4574 | 8.3406 | 9.2708 | 7.9605 | 8.0581 | 8.7453 | 8.2201 | 7.7950 | 7.8343 | 7.7056 | 8.6662 | 8.1413 | 9.3782 | 8.3212 | 8.2590 | 8.4163 | 7.8371 | 7.7514 | 7.7178 | 8.2449 | 9.2802 | 7.4758 | 7.8004 | 8.1096 | 8.7453 | 7.4566 | 7.4959 | 7.8321 | 7.3019 | 9.1487 | 8.0437 | 7.7137 | 8.4543 | 8.2295 | 7.7705 | 8.0433 | 7.7391 | 8.2973 | 8.2072 | 8.3391 | 7.4007 | 8.1297 | 8.0389 | 8.7798 | 7.9316 | 8.5271 | 9.0240 | 8.5403 | 8.0707 | 8.9380 | 7.8732 | 7.6676 | 8.0776 | 9.0159 | 8.0729 | 8.3924 | 8.0298 | 8.0371 | 7.9291 | 8.1403 | 7.8380 | 8.7334 | 8.2232 | 7.5530 | 7.2344 | 9.0005 | 8.4329 | 8.7808 | 8.2056 | 8.2778 | 9.8795 | 8.0474 | 8.4574 | 8.9161 | 8.1947 | 8.8291 | 8.7155 | 8.2430 | 8.5855 | 8.2050 | 7.8230 | 8.3648 | 8.4147 | 7.7184 | 8.5858 | 8.0336 | 7.9617 | 7.5593 | 7.7784 | 8.5657 | 7.2378 | 8.8090 | 9.2529 | 7.2240 | 8.1896 | 8.2891 | 7.5244 | 9.0049 | 8.3953 | 8.0747 | 8.1542 | 8.3347 | 8.3931 | 9.1437 | 7.8757 | 8.9449 | 7.9821 | 8.6144 | 8.2352 | 8.4860 | 8.8862 | 7.6531 | 7.6629 | 8.2063 | 7.5219 | 7.8274 | 8.8530 | 8.1884 | 8.9192 | 7.7231 | 7.8898 | 7.6516 | 8.9766 | 8.6838 | 8.8605 | 9.0705 | 8.3262 | 8.6994 | 7.8468 | 8.3322 | 8.0182 | 8.2166 | 8.2232 | 9.0071 | 12.2890 | 7.9947 | 7.3091 | 8.0929 | 9.1129 | 8.0342 | 8.0791 | 8.6169 | 8.3058 | 8.5076 | 8.1645 | 7.7652 | 7.2422 | 7.8007 | 8.3777 | 8.2603 | 9.2705 | 7.8600 | 7.6013 | 7.5291 | 7.7457 | 7.6189 | 8.1570 | 7.6902 | 7.9944 | 7.4491 | 8.0474 | 8.5776 | 7.9671 | 7.7090 | 8.7330 | 7.7903 | 8.1808 | 7.7680 | 7.5379 | 8.1011 | 7.5517 | 8.3243 | 7.1829 | 7.6403 | 8.4514 | 7.5367 | 8.4248 | 8.0986 | 8.5017 | 7.7664 | 8.4612 | 9.0294 | 8.3962 | 7.9827 | 7.8509 | 8.8812 | 8.2179 | 8.1924 | 7.2469 | 8.3425 | 7.6864 | 7.6139 | 8.8197 | 8.2508 | 8.0490 | 7.5348 | 8.2756 | 7.0702 | 7.1012 | 8.4816 | 8.3419 | 8.6162 | 8.0967 | 7.6842 | 8.0587 | 9.3810 | 7.7847 | 6.8975 | 8.2063 | 7.7351 | 7.4635 | 7.8873 | 9.8148 | 8.2596 | 7.5944 | 8.1378 | 7.8999 | 7.8270 | 9.0501 | 8.2640 | 7.8625 | 8.4511 | 6.8482 | 7.8955 | 7.6289 | 7.4651 | 7.4666 | 8.0264 | 8.2144 | 8.0374 | 7.5793 | 8.2113 | 8.8737 | 9.1553 | 8.0038 | 7.4073 | 7.6440 | 8.1209 | 7.8261 | 7.8270 | 8.9584 | 7.8424 | 7.7705 | 7.8908 | 7.6682 | 8.3438 | 8.9317 | 7.4867 | 8.3281 | 7.7690 | 8.7387 | 8.7399 | 7.8066 | 7.5900 | 7.9903 | 7.9620 | 7.7052 | 7.3257 | 7.5385 | 8.0022 | 7.7442 | 7.3863 | 6.8802 | 8.2295 | 7.8726 | 8.2408 | 7.0833 | 8.1466 | 7.1992 | 7.7012 | 7.1533 | 7.7228 | 7.1791 | 7.3979 | 7.9303 | 7.8939 | 7.5181 | 7.7856 | 8.2807 | 6.8049 | 8.1224 | 6.9942 | 7.5680 | 8.2907 | 7.5746 | 9.01395 |
| STPG1 | 8.2748 | 8.0578 | 8.0821 | 7.6324 | 8.0831 | 8.0889 | 6.2686 | 7.6557 | 7.1719 | 7.6888 | 8.2680 | 8.5717 | 8.4325 | 8.4316 | 8.0286 | 7.5983 | 8.5591 | 8.4549 | 8.2164 | 8.5493 | 8.1016 | 8.7090 | 8.9465 | 8.8472 | 7.8718 | 9.1694 | 7.7054 | 8.5902 | 8.9631 | 7.5603 | 7.9682 | 8.7528 | 8.5591 | 8.7450 | 8.0110 | 8.1444 | 8.4471 | 7.4328 | 7.6148 | 7.7910 | 8.0305 | 8.6710 | 9.0585 | 9.3291 | 9.4498 | 8.2992 | 7.6178 | 8.7518 | 8.1463 | 8.4861 | 7.8183 | 9.0020 | 8.6301 | 8.4121 | 8.0363 | 7.5564 | 8.5386 | 8.3887 | 7.9633 | 8.1162 | 8.6097 | 9.2025 | 8.4909 | 8.4695 | 8.0402 | 8.0432 | 7.9380 | 8.0461 | 8.0286 | 8.5211 | 8.3342 | 7.8310 | 8.1824 | 7.9371 | 8.0617 | 7.9789 | 8.4724 | 9.0273 | 8.2437 | 8.4247 | 8.4802 | 8.4325 | 8.3294 | 7.6879 | 7.9468 | 7.8894 | 8.3264 | 8.0081 | 7.7725 | 7.5058 | 8.2661 | 7.8991 | 9.2862 | 8.7100 | 8.3478 | 7.7171 | 8.1833 | 7.8592 | 7.7998 | 7.5788 | 7.1495 | 7.9663 | 7.7988 | 7.6051 | 8.1629 | 8.1746 | 7.7813 | 8.3858 | 8.1094 | 7.7044 | 7.9351 | 8.3926 | 8.1045 | 7.8494 | 8.5669 | 9.0507 | 8.4014 | 8.1356 | 8.4510 | 8.3790 | 7.6041 | 8.0733 | 7.8183 | 8.0334 | 7.1943 | 8.0247 | 7.9195 | 7.6431 | 7.7891 | 7.8017 | 7.9478 | 7.9663 | 8.1668 | 7.9896 | 7.8368 | 8.2116 | 8.4228 | 7.9867 | 8.7635 | 7.3423 | 10.1390 | 7.5788 | 8.6915 | 8.2476 | 8.3147 | 8.6233 | 8.1434 | 8.3118 | 7.8602 | 7.1272 | 8.6019 | 8.0422 | 8.5046 | 8.0354 | 8.1220 | 8.4101 | 8.0811 | 8.3284 | 8.4189 | 8.2262 | 7.4669 | 7.0551 | 7.5097 | 8.8073 | 7.5915 | 8.4617 | 8.6048 | 7.5701 | 7.9322 | 7.7453 | 7.8748 | 7.6606 | 8.2067 | 8.7645 | 8.0315 | 7.5710 | 8.4501 | 7.6849 | 7.6937 | 8.3225 | 8.5163 | 9.1811 | 8.5834 | 8.4355 | 8.1269 | 7.3043 | 8.3255 | 7.1690 | 7.7073 | 7.7599 | 8.5708 | 7.6343 | 7.1301 | 8.6808 | 8.8278 | 8.2602 | 8.0315 | 8.2417 | 7.9487 | 7.9672 | 8.2534 | 7.4114 | 7.1953 | 8.1055 | 7.7502 | 8.2252 | 8.5747 | 7.9857 | 7.5594 | 8.6428 | 7.6528 | 8.3050 | 8.5240 | 6.8351 | 9.0750 | 8.6447 | 8.4306 | 8.1230 | 8.0860 | 8.0617 | 8.0529 | 8.0646 | 8.2524 | 9.0185 | 7.0960 | 8.3624 | 8.2817 | 8.1590 | 7.3530 | 8.2009 | 7.4533 | 8.1288 | 8.1668 | 7.5886 | 7.5000 | 8.1103 | 7.5233 | 7.4260 | 7.8475 | 7.8913 | 8.3926 | 8.1726 | 8.3079 | 7.8767 | 8.1833 | 7.7394 | 8.2174 | 8.0986 | 7.5886 | 7.1924 | 7.6538 | 8.5532 | 7.8816 | 8.3323 | 8.3926 | 8.4355 | 7.3579 | 7.5525 | 7.2790 | 8.1055 | 8.0325 | 8.3031 | 8.2515 | 8.2349 | 8.4549 | 8.8492 | 7.8962 | 7.8650 | 7.7064 | 7.6197 | 8.7255 | 8.0266 | 8.7022 | 7.8446 | 8.0101 | 7.8456 | 8.1025 | 8.1142 | 8.5201 | 7.9789 | 7.8329 | 7.4056 | 8.0237 | 8.2242 | 7.7813 | 8.0110 | 8.2476 | 7.6353 | 8.1035 | 8.2252 | 8.6808 | 7.8942 | 8.5669 | 8.4403 | 7.8786 | 8.2466 | 7.9906 | 8.5523 | 8.9893 | 8.7849 | 7.6918 | 8.4267 | 8.2904 | 8.3732 | 8.3770 | 8.2223 | 8.4637 | 8.3157 | 8.2340 | 8.7314 | 7.7628 | 7.7326 | 8.5717 | 8.0081 | 8.3809 | 8.0451 | 8.3449 | 8.5980 | 8.6087 | 7.6518 | 6.9772 | 8.6389 | 7.6606 | 8.1142 | 8.8190 | 8.4218 | 8.6652 | 7.7502 | 7.6956 | 7.9273 | 9.3057 | 8.6603 | 8.0120 | 9.0504 | 8.3382 | 8.0960 | 8.4664 | 8.4328 | 7.4855 | 7.7918 | 7.7104 | 8.4603 | 7.7338 | 9.2508 | 8.8500 | 8.8337 | 7.6565 | 8.2863 | 7.6137 | 7.8986 | 8.8774 | 7.9932 | 8.7950 | 8.5600 | 7.4245 | 8.3046 | 7.7877 | 7.9414 | 7.8844 | 8.5895 | 8.2507 | 7.9688 | 8.0787 | 8.0024 | 8.8947 | 8.1072 | 8.2456 | 7.6687 | 8.0421 | 8.2110 | 7.3848 | 7.9922 | 8.3005 | 8.4043 | 8.6363 | 8.4613 | 7.7714 | 8.4379 | 7.5293 | 7.2505 | 8.6037 | 8.5254 | 8.5244 | 8.1153 | 9.1511 | 7.8213 | 8.5091 | 7.2596 | 7.9393 | 8.6526 | 7.7796 | 6.8059 | 8.0085 | 7.9994 | 8.7655 | 7.9139 | 8.0930 | 8.0675 | 7.9922 | 8.2802 | 8.2568 | 8.2273 | 7.5089 | 8.4745 | 8.3148 | 7.6493 | 7.0958 | 8.0655 | 7.5730 | 7.6565 | 8.6566 | 8.2975 | 8.1031 | 7.5974 | 7.6524 | 8.6170 | 9.2590 | 7.8986 | 7.8386 | 8.0940 | 7.6331 | 7.1304 | 8.6302 | 8.2669 | 7.3980 | 8.3646 | 8.1947 | 8.0584 | 8.5956 | 7.7816 | 8.2212 | 7.5293 | 8.0879 | 7.7185 | 7.4957 | 8.3076 | 8.5661 | 8.5193 | 8.9415 | 8.0329 | 8.1896 | 7.9485 | 8.3117 | 7.2261 | 8.5081 | 7.8691 | 7.7582 | 8.5844 | 7.8905 | 8.1398 | 8.0228 | 8.7920 | 8.9710 | 7.6280 | 8.1815 | 8.2720 | 8.0085 | 7.3990 | 8.2659 | 8.9059 | 8.8072 | 8.4074 | 7.7745 | 7.5954 | 8.3138 | 8.7502 | 8.0523 | 8.7675 | 7.5506 | 7.9729 | 8.2741 | 8.6709 | 7.3634 | 7.4509 | 7.9912 | 9.4309 | 8.2761 | 7.7928 | 8.0065 | 7.8284 | 8.3565 | 8.3402 | 8.7116 | 7.8416 | 7.9200 | 8.4877 | 8.2680 | 8.6526 | 8.5244 | 8.2273 | 7.8508 | 8.4613 | 7.5506 | 7.7379 | 8.2405 | 7.8070 | 7.7582 | 8.2619 | 8.1113 | 7.7318 | 8.2161 | 8.1906 | 8.0482 | 8.4999 | 7.9149 | 7.6565 | 9.1277 | 8.3687 | 8.8327 | 7.9424 | 7.6575 | 7.8701 | 8.0950 | 7.6931 | 8.7665 | 8.2792 | 9.6843 | 8.2893 | 8.4816 | 8.1957 | 8.3046 | 7.4703 | 8.0757 | 7.9118 | 8.8846 | 8.1662 | 8.0329 | 7.7562 | 6.9208 | 8.3494 | 7.8040 | 8.3463 | 8.4562 | 8.2354 | 8.4084 | 8.2527 | 8.0095 | 8.6526 | 7.7145 | 8.0105 | 7.7592 | 7.2861 | 7.3360 | 8.2822 | 7.8264 | 8.3656 | 8.3972 | 7.7104 | 7.9118 | 8.1459 | 8.3015 | 8.0624 | 8.1530 | 8.0055 | 8.7431 | 8.7289 | 8.7248 | 7.7084 | 8.3565 | 7.3003 | 8.4562 | 7.6870 | 7.2434 | 8.6872 | 8.2140 | 7.5812 | 8.6363 | 9.2386 | 8.1357 | 8.8988 | 7.8366 | 8.6973 | 7.9617 | 7.8925 | 8.1754 | 7.8946 | 7.7694 | 7.2902 | 7.5944 | 7.8132 | 8.5834 | 7.5344 | 7.6168 | 6.8801 | 8.4287 | 8.5406 | 7.8396 | 8.2496 | 8.3453 | 8.4124 | 7.9302 | 8.6109 | 8.6027 | 7.5771 | 7.4174 | 8.1957 | 8.6841 | 8.0105 | 7.6677 | 7.4072 | 7.5425 | 9.6772 | 8.4145 | 8.0594 | 8.8734 | 7.9251 | 8.1845 | 8.1418 | 7.8569 | 8.3748 | 7.5781 | 8.2374 | 8.0411 | 8.8591 | 8.3789 | 7.7440 | 8.6760 | 8.0472 | 8.1225 | 8.0004 | 8.5600 | 7.9159 | 7.8060 | 7.5211 | 8.8713 | 7.6239 | 7.8671 | 7.6900 | 8.0726 | 7.5333 | 8.5244 | 8.3229 | 7.9536 | 7.5395 | 7.3929 | 7.9658 | 8.5193 | 8.0818 | 8.2527 | 8.1540 | 8.5274 | 8.0838 | 8.2110 | 8.8540 | 8.4918 | 7.6707 | 8.0217 | 7.9037 | 8.5722 | 8.3026 | 8.6770 | 8.8286 | 8.0573 | 7.6890 | 8.0248 | 8.2283 | 8.2771 | 8.5763 | 7.6972 | 8.6556 | 8.0655 | 8.5172 | 8.6393 | 8.5936 | 8.4297 | 8.3616 | 7.5242 | 8.3931 | 8.4440 | 8.2252 | 8.0472 | 8.0451 | 7.9973 | 7.7918 | 8.0207 | 7.8101 | 7.7338 | 7.9810 | 7.3838 | 9.2254 | 8.0655 | 8.5478 | 7.2861 | 8.6281 | 8.0166 | 7.8111 | 9.3241 | 7.5272 | 8.5895 | 8.2161 | 8.9822 | 8.0258 | 7.2424 | 7.7541 | 8.5050 | 8.2914 | 8.1510 | 8.2893 | 8.6597 | 8.0187 | 8.8082 | 7.9973 | 7.5120 | 8.1571 | 8.0248 | 8.1245 | 8.4735 | 7.4367 | 8.3758 | 7.8610 | 7.9434 | 8.1469 | 9.2569 | 7.8488 | 8.6638 | 8.0187 | 8.0523 | 8.5600 | 7.3309 | 7.6473 | 7.4428 | 7.2078 | 7.7419 | 9.1705 | 7.6585 | 8.0665 | 7.4927 | 7.9281 | 8.5020 | 8.0940 | 8.2934 | 8.0736 | 7.6727 | 7.7246 | 8.8245 | 8.2578 | 7.0358 | 8.9395 | 7.8813 | 7.4469 | 8.5895 | 8.4399 | 8.3463 | 8.9487 | 7.9037 | 7.1457 | 7.5354 | 8.6119 | 8.8530 | 7.9800 | 7.9108 | 8.3911 | 8.4806 | 7.5812 | 7.9363 | 8.1174 | 7.6656 | 8.4297 | 8.0726 | 8.0502 | 8.5040 | 8.7228 | 8.2802 | 8.5162 | 7.6972 | 7.7786 | 8.3209 | 8.1021 | 9.1501 | 8.1387 | 8.6373 | 9.3495 | 8.0950 | 7.8305 | 8.2161 | 7.0643 | 7.8142 | 8.4806 | 8.2690 | 8.6424 | 8.0655 | 8.3209 | 7.8630 | 8.4613 | 8.9863 | 8.1571 | 7.7745 | 7.6575 | 7.4652 | 8.7268 | 8.1978 | 8.1092 | 7.9810 | 8.5732 | 7.5710 | 7.6585 | 7.9434 | 8.0523 | 8.1031 | 8.4796 | 8.6709 | 8.3056 | 7.8467 | 8.0044 | 8.6210 | 8.3249 | 8.3555 | 8.6454 | 9.0748 | 7.6198 | 7.2434 | 9.3383 | 8.2252 | 7.6809 | 8.0380 | 8.2039 | 7.2576 | 8.2914 | 8.2944 | 8.1123 | 8.3219 | 8.7065 | 7.8620 | 9.1572 | 8.4409 | 6.9575 | 8.4114 | 8.5050 | 7.9556 | 7.7704 | 8.3748 | 7.9668 | 8.3351 | 7.7022 | 7.7511 | 8.2110 | 8.7808 | 7.7104 | 8.3056 | 9.2498 | 8.6027 | 7.9332 | 8.3046 | 7.1426 | 7.7999 | 8.8489 | 7.9546 | 8.2405 | 9.2529 | 7.7816 | 7.1386 | 8.6017 | 7.9525 | 8.1235 | 8.8205 | 8.1184 | 7.8803 | 8.0665 | 7.9098 | 7.6158 | 7.3614 | 8.1296 | 8.2486 | 7.5506 | 7.6666 | 8.6790 | 8.2873 | 8.4755 | 7.8488 | 8.2120 | 7.4743 | 8.0411 | 8.1042 | 8.8154 | 7.5161 | 8.1042 | 7.4306 | 8.8879 | 7.1846 | 8.1990 | 7.8877 | 8.6844 | 8.0952 | 7.5957 | 8.0006 | 7.9141 | 7.3423 | 7.9335 | 8.3852 | 7.8073 | 8.9856 | 8.1441 | 7.7127 | 8.6722 | 8.7149 | 9.3498 | 7.7208 | 7.8633 | 8.0668 | 8.6182 | 7.8022 | 9.2175 | 7.7595 | 8.0963 | 7.6313 | 7.1429 | 8.2886 | 8.3588 | 7.6221 | 8.1634 | 7.2894 | 9.6937 | 7.9681 | 8.6966 | 9.4322 | 7.5020 | 8.5195 | 7.2894 | 7.9324 | 7.5733 | 7.9477 | 7.7350 | 8.0963 | 7.9243 | 8.0006 | 8.5053 | 7.4888 | 8.4849 | 8.7525 | 7.9090 | 8.0902 | 7.9589 | 8.1461 | 8.2275 | 7.8907 | 7.8490 | 7.9874 | 8.0403 | 8.4056 | 7.6893 | 8.3140 | 7.6374 | 7.5722 | 8.7251 | 7.6425 | 7.0615 | 8.6416 | 7.5570 | 7.5458 | 7.5997 | 8.1838 | 8.1563 | 7.7371 | 7.3138 | 7.6903 | 8.4188 | 7.5570 | 8.1482 | 8.5724 | 8.0118 | 8.5613 | 7.8592 | 8.0199 | 8.1400 | 7.8012 | 8.3720 | 6.7399 | 7.4613 | 7.8531 | 8.3445 | 7.3433 | 7.6536 | 7.3606 | 7.5824 | 6.8468 | 7.7625 | 8.1400 | 7.9650 | 8.5012 | 7.5997 | 8.2794 | 7.3759 | 7.2762 | 7.1093 | 8.6070 | 7.7656 | 8.80495 |
| NIPAL3 | 6.9615 | 7.3208 | 7.5856 | 7.2215 | 7.8767 | 7.9375 | 6.9534 | 7.0362 | 7.8405 | 7.3266 | 8.6462 | 7.9910 | 7.9778 | 8.4041 | 6.9260 | 7.4698 | 7.9111 | 7.9884 | 8.2441 | 8.1137 | 7.6105 | 8.0565 | 7.4878 | 7.6852 | 8.0628 | 8.3920 | 7.3266 | 7.8123 | 8.7718 | 6.9571 | 7.5687 | 8.4565 | 7.7269 | 7.8375 | 7.3123 | 7.9782 | 7.9972 | 7.0871 | 7.4973 | 7.0930 | 7.6317 | 7.5017 | 8.4466 | 8.1375 | 8.6802 | 8.2902 | 6.9952 | 7.9309 | 7.6258 | 8.4763 | 7.2047 | 8.2323 | 7.2197 | 7.9701 | 7.9679 | 7.6614 | 7.2054 | 7.5793 | 7.0593 | 7.9675 | 8.6019 | 8.1309 | 7.9873 | 8.0738 | 8.1338 | 7.3603 | 7.9822 | 7.5478 | 7.7588 | 7.5105 | 7.2724 | 7.4973 | 6.8326 | 7.2032 | 7.2303 | 7.9467 | 7.8042 | 7.6225 | 7.3969 | 6.9487 | 6.9113 | 8.3737 | 8.4997 | 7.2933 | 7.3874 | 8.1807 | 7.3424 | 7.8452 | 9.2827 | 7.8163 | 7.6515 | 7.0497 | 7.4548 | 8.2038 | 7.6910 | 7.3856 | 7.9287 | 7.7200 | 8.2898 | 7.1882 | 6.9340 | 7.4255 | 7.7317 | 7.2955 | 7.4775 | 8.4638 | 7.7141 | 7.6090 | 8.3884 | 7.8492 | 7.4013 | 8.0954 | 7.9467 | 7.5445 | 8.3301 | 8.4275 | 7.7379 | 7.5486 | 8.0770 | 8.2294 | 7.0439 | 7.3695 | 7.3691 | 7.9188 | 6.8450 | 7.2596 | 7.2834 | 7.4903 | 7.8236 | 8.1671 | 7.1519 | 8.2400 | 7.4229 | 7.9500 | 7.5537 | 7.7917 | 7.7537 | 6.9853 | 7.8324 | 6.2356 | 8.2199 | 7.1948 | 8.1565 | 7.3431 | 7.5105 | 8.0727 | 8.3331 | 8.1649 | 7.4727 | 7.2622 | 8.3444 | 8.3133 | 8.4078 | 7.5830 | 7.0897 | 8.0836 | 7.0941 | 8.3287 | 8.0540 | 8.6381 | 7.4515 | 6.3759 | 6.9520 | 7.3046 | 7.3197 | 6.9029 | 8.3129 | 7.1614 | 7.0908 | 7.3801 | 7.1281 | 7.5735 | 7.0999 | 8.0265 | 7.1124 | 7.3955 | 8.5902 | 7.2607 | 8.0752 | 8.4250 | 7.4654 | 8.2979 | 8.6945 | 7.7320 | 7.6024 | 8.1455 | 7.3834 | 6.7278 | 7.3563 | 7.9463 | 7.6050 | 7.3486 | 7.6658 | 7.7617 | 7.9829 | 7.9071 | 7.3977 | 7.4815 | 6.5978 | 7.4120 | 8.3645 | 7.2966 | 7.4152 | 7.1329 | 7.7683 | 7.8903 | 8.0496 | 7.7573 | 6.8765 | 7.6431 | 7.7112 | 7.9708 | 7.6365 | 6.9270 | 8.2770 | 7.4735 | 8.1638 | 7.7830 | 7.8060 | 8.0119 | 7.2376 | 7.6482 | 8.0313 | 8.2807 | 7.0483 | 8.4752 | 7.3409 | 8.9198 | 7.4163 | 7.1215 | 7.4354 | 7.5541 | 7.9833 | 8.0576 | 7.3200 | 6.8066 | 6.9637 | 8.3836 | 8.1316 | 7.2252 | 7.3830 | 7.9306 | 7.4270 | 8.1023 | 8.0291 | 8.2843 | 7.7416 | 7.7141 | 7.3867 | 7.2482 | 7.4771 | 7.7126 | 7.2775 | 7.9078 | 7.7324 | 7.7258 | 7.4966 | 7.5628 | 7.2611 | 8.3550 | 7.0820 | 7.4222 | 7.4548 | 7.7405 | 8.8110 | 7.3933 | 7.6705 | 7.6013 | 6.7326 | 7.7584 | 7.7134 | 8.3385 | 7.6024 | 7.7247 | 7.6086 | 7.7562 | 7.9895 | 7.5647 | 7.4138 | 7.6299 | 7.6160 | 7.7339 | 7.9503 | 6.9600 | 7.4248 | 7.5010 | 8.2510 | 6.8468 | 7.8749 | 7.3321 | 7.4940 | 7.7602 | 7.6811 | 7.6639 | 8.4931 | 7.0464 | 7.2395 | 8.3656 | 8.0247 | 7.6639 | 7.7932 | 7.4017 | 7.0340 | 7.5665 | 7.1340 | 7.9983 | 7.4878 | 8.0404 | 7.6562 | 8.9051 | 7.1109 | 8.4334 | 8.2243 | 8.2162 | 7.6570 | 8.0620 | 8.1833 | 7.5892 | 8.2452 | 7.2127 | 7.3713 | 7.8071 | 8.0514 | 8.3221 | 8.0836 | 7.2497 | 7.5548 | 6.7619 | 7.6156 | 7.8170 | 8.1704 | 7.0801 | 7.7456 | 8.3363 | 7.5924 | 6.8409 | 7.9453 | 7.5228 | 7.4183 | 10.4330 | 6.5905 | 8.9515 | 7.3659 | 8.4345 | 8.4379 | 7.5066 | 7.5752 | 7.8861 | 7.7150 | 7.4374 | 6.9420 | 7.6697 | 8.3745 | 7.4913 | 7.2748 | 7.5671 | 6.8604 | 7.2181 | 8.0902 | 7.7002 | 7.3430 | 7.0025 | 7.2309 | 7.8513 | 8.8742 | 7.9019 | 7.6706 | 7.8184 | 8.3187 | 7.4446 | 7.4489 | 7.4255 | 9.3115 | 8.1017 | 7.4861 | 7.8027 | 7.4322 | 7.5643 | 7.2243 | 7.9939 | 7.7593 | 7.7917 | 7.9582 | 7.7054 | 8.3153 | 7.8485 | 7.6377 | 7.3482 | 7.3664 | 7.8308 | 7.8227 | 6.8676 | 7.4698 | 7.4298 | 8.2567 | 7.0745 | 7.1685 | 8.1389 | 7.8490 | 7.8122 | 7.8165 | 8.1642 | 7.5190 | 7.6668 | 7.7922 | 7.2748 | 7.5471 | 7.3811 | 7.2886 | 7.6134 | 7.3449 | 7.5500 | 7.6987 | 7.4589 | 7.7097 | 7.4331 | 9.1656 | 7.6429 | 7.6496 | 7.7684 | 7.4555 | 8.1112 | 7.4040 | 7.5681 | 7.7088 | 7.9853 | 7.3955 | 7.1370 | 8.5170 | 7.3153 | 8.0025 | 7.1351 | 7.7684 | 7.5323 | 7.0769 | 7.4732 | 7.3511 | 8.0216 | 7.4026 | 7.7874 | 7.8752 | 7.7355 | 7.5776 | 7.4951 | 7.9529 | 7.2657 | 7.4970 | 7.8232 | 7.8914 | 8.3020 | 7.4784 | 7.3263 | 8.2600 | 8.3449 | 7.7116 | 8.1003 | 8.3048 | 7.8575 | 7.6162 | 7.5147 | 7.1532 | 7.5113 | 7.6000 | 8.1193 | 7.9295 | 8.1346 | 7.5957 | 8.3878 | 7.2834 | 7.9434 | 7.3497 | 7.6787 | 7.7583 | 7.5047 | 7.3726 | 8.5838 | 7.6921 | 7.2066 | 7.9963 | 7.7746 | 8.0998 | 7.7831 | 7.9190 | 7.7736 | 7.1980 | 8.1947 | 6.9725 | 8.3530 | 8.2972 | 7.5261 | 7.8637 | 7.7173 | 7.5647 | 7.4155 | 8.3058 | 7.7107 | 7.4083 | 7.2104 | 7.9615 | 6.9238 | 8.1990 | 7.4036 | 8.0745 | 8.6801 | 7.9968 | 7.4627 | 8.4808 | 7.5171 | 7.9033 | 7.7583 | 7.8017 | 7.5361 | 7.0597 | 7.8914 | 9.3496 | 7.7464 | 8.2619 | 8.6477 | 8.6095 | 7.6973 | 8.1136 | 7.3440 | 7.9729 | 7.2157 | 8.4961 | 7.0512 | 8.3959 | 7.5018 | 6.5552 | 7.8866 | 7.4307 | 7.5848 | 7.7488 | 7.6458 | 8.0015 | 8.7207 | 8.0936 | 8.1713 | 7.6968 | 7.5504 | 7.6849 | 7.7002 | 7.1642 | 7.5943 | 7.5666 | 7.6115 | 7.9257 | 7.2190 | 8.1575 | 6.7731 | 7.9472 | 7.1117 | 7.9801 | 7.3893 | 8.3954 | 7.4422 | 7.4675 | 8.0135 | 8.5847 | 7.1275 | 7.6849 | 7.6577 | 7.1279 | 8.2753 | 7.8475 | 7.3969 | 8.7378 | 9.0783 | 6.9453 | 7.5934 | 7.4999 | 7.6282 | 7.3106 | 7.2734 | 7.7397 | 7.6072 | 7.7755 | 7.3435 | 7.4908 | 7.3835 | 7.9033 | 7.6778 | 7.5104 | 7.0068 | 7.5042 | 7.2958 | 7.5385 | 8.6057 | 7.5619 | 8.2419 | 7.2529 | 8.4093 | 7.9739 | 7.3349 | 7.1728 | 7.9562 | 7.9868 | 7.6267 | 7.8876 | 7.5671 | 7.0507 | 9.7745 | 7.9458 | 7.5843 | 7.7374 | 7.8847 | 7.4336 | 7.7903 | 7.0740 | 7.3401 | 7.6468 | 7.4365 | 7.3897 | 8.2881 | 8.8480 | 7.5337 | 7.8733 | 7.6506 | 7.6396 | 7.3969 | 7.7574 | 6.7002 | 7.5581 | 7.3449 | 8.9042 | 7.6391 | 7.4980 | 8.1279 | 7.5442 | 6.8652 | 7.5428 | 7.6620 | 7.4641 | 8.4622 | 8.4116 | 7.4369 | 7.9438 | 8.2066 | 7.2843 | 7.6258 | 7.8084 | 7.7388 | 7.6067 | 7.4956 | 7.1356 | 7.2548 | 7.6096 | 7.2638 | 7.9624 | 7.8280 | 6.9639 | 8.3621 | 7.8585 | 7.2829 | 7.9610 | 7.2352 | 7.5366 | 8.2290 | 7.5395 | 7.9067 | 7.2028 | 8.2786 | 8.0573 | 8.1575 | 8.1432 | 8.0836 | 7.1914 | 7.4512 | 7.7974 | 7.7507 | 7.4555 | 8.1913 | 7.7984 | 7.2777 | 7.9238 | 7.6201 | 7.4632 | 7.4698 | 7.6372 | 7.8861 | 7.1227 | 8.1751 | 7.5237 | 8.6081 | 7.1489 | 7.4684 | 7.5900 | 7.3697 | 8.1065 | 7.7345 | 8.2958 | 7.5433 | 7.4350 | 8.0011 | 8.0058 | 8.1260 | 9.2123 | 7.6549 | 7.4756 | 7.5027 | 8.4755 | 8.3315 | 8.4441 | 8.0640 | 7.5414 | 7.6339 | 8.2419 | 7.1561 | 8.0588 | 7.2233 | 7.8375 | 7.8652 | 8.9252 | 7.5776 | 7.9505 | 7.7979 | 7.7240 | 8.0807 | 7.1084 | 7.6687 | 7.6072 | 7.2033 | 7.7698 | 8.7497 | 7.4169 | 7.7259 | 7.4737 | 7.6420 | 7.9863 | 7.8122 | 8.3745 | 7.6806 | 7.1575 | 7.4551 | 7.7388 | 8.2867 | 7.4155 | 7.8284 | 6.5958 | 7.3125 | 7.6649 | 7.8399 | 7.6635 | 7.9839 | 7.4164 | 7.5476 | 8.1107 | 8.3349 | 7.4341 | 7.2610 | 7.1365 | 7.9286 | 7.8232 | 7.2204 | 8.0087 | 7.9624 | 8.2385 | 7.8828 | 8.5681 | 8.2414 | 7.5380 | 7.5662 | 7.3239 | 7.7016 | 7.3726 | 7.7984 | 7.7808 | 7.7936 | 7.3382 | 7.4164 | 7.2777 | 8.6229 | 7.2805 | 7.4145 | 7.6830 | 7.0855 | 6.7269 | 7.1580 | 7.0912 | 7.8575 | 6.7932 | 8.0840 | 7.3583 | 8.4045 | 7.4760 | 7.1379 | 7.1465 | 7.8222 | 6.8499 | 8.0244 | 6.8652 | 7.1809 | 7.4455 | 7.1027 | 7.8180 | 7.5204 | 7.7102 | 7.9605 | 7.7178 | 7.7908 | 7.5962 | 7.9653 | 7.4145 | 7.2872 | 7.7388 | 8.1937 | 7.8394 | 7.5395 | 8.4007 | 7.2324 | 8.2877 | 9.8661 | 7.9300 | 7.4865 | 8.0015 | 7.5419 | 6.9796 | 8.1427 | 8.5342 | 8.5104 | 7.5280 | 7.8428 | 7.0340 | 7.9281 | 8.0063 | 6.3330 | 8.1842 | 7.7798 | 7.4951 | 7.5481 | 7.4298 | 7.1251 | 7.4679 | 7.8056 | 6.7007 | 7.5428 | 7.5314 | 6.4026 | 7.4384 | 8.6897 | 8.1336 | 7.2252 | 7.6215 | 6.9644 | 7.2667 | 7.6243 | 7.6496 | 7.3502 | 8.1532 | 7.0349 | 7.1341 | 7.4875 | 7.0831 | 7.7927 | 8.1999 | 7.4908 | 7.1980 | 7.1213 | 7.5213 | 7.1608 | 7.0993 | 7.0502 | 7.7812 | 6.9386 | 6.6907 | 7.5838 | 6.9591 | 7.0273 | 6.8895 | 7.1084 | 7.5337 | 8.1141 | 8.3559 | 7.4160 | 7.4040 | 7.3506 | 7.6964 | 7.9701 | 7.5018 | 8.7316 | 7.7855 | 7.7259 | 10.3577 | 7.4822 | 8.5142 | 7.7645 | 7.6143 | 7.8756 | 7.5857 | 7.7202 | 8.2581 | 7.2047 | 7.7679 | 8.9076 | 8.5213 | 8.0993 | 7.2910 | 7.7469 | 7.4040 | 8.1260 | 6.9658 | 9.2481 | 7.2247 | 7.5933 | 6.5671 | 7.5709 | 7.1870 | 7.9453 | 6.9338 | 8.2853 | 7.2452 | 8.5814 | 8.6105 | 8.0192 | 7.8656 | 7.1818 | 7.4970 | 6.8685 | 7.3797 | 9.7712 | 7.6820 | 7.6024 | 8.5752 | 8.0869 | 7.0974 | 8.5404 | 7.9448 | 8.4112 | 7.9696 | 8.6248 | 7.7679 | 7.6157 | 8.1756 | 7.4755 | 7.7454 | 6.9357 | 7.1689 | 6.9605 | 8.4622 | 7.6253 | 7.2743 | 7.5533 | 7.6095 | 7.7798 | 7.1618 | 6.5366 | 7.8966 | 7.4307 | 7.1651 | 7.3601 | 7.0683 | 7.8065 | 7.8971 | 7.5824 | 6.9291 | 7.9028 | 7.5495 | 7.7140 | 7.9319 | 7.2605 | 8.2128 | 7.5590 | 7.0945 | 7.7817 | 7.4598 | 9.6610 | 7.5528 | 7.9691 | 7.8046 | 7.7130 | 7.6477 | 7.7636 | 7.9710 | 7.3601 | 7.8060 | 7.5671 | 8.3463 | 7.5170 | 8.2762 | 7.6095 | 7.9295 | 8.7535 | 6.9043 | 8.4889 | 9.0654 | 7.4875 | 8.40200 |
| LAS1L | 12.4860 | 12.4020 | 12.1390 | 12.2450 | 12.2250 | 12.3380 | 12.1710 | 11.7540 | 12.3760 | 11.9090 | 12.7520 | 12.3670 | 11.9690 | 12.0230 | 12.0800 | 12.3010 | 12.1020 | 11.5150 | 12.1520 | 13.7310 | 12.7810 | 12.2580 | 12.4800 | 11.9000 | 12.2130 | 13.2720 | 12.0220 | 12.3520 | 12.6880 | 13.0980 | 12.4260 | 11.8830 | 13.2360 | 12.6000 | 12.3420 | 12.4000 | 11.9840 | 12.1390 | 12.0900 | 12.5040 | 12.0670 | 11.9250 | 12.7660 | 12.3450 | 12.6060 | 11.9440 | 12.7520 | 12.7770 | 11.6670 | 12.3730 | 12.8150 | 12.7610 | 11.3570 | 13.3220 | 12.2450 | 12.3340 | 12.1240 | 12.3160 | 11.8290 | 12.2780 | 12.7400 | 11.4010 | 12.1260 | 12.3380 | 12.0990 | 11.4760 | 12.5510 | 11.5910 | 12.0390 | 12.5110 | 12.0260 | 12.7330 | 11.7540 | 12.3540 | 12.4970 | 11.9220 | 12.1900 | 12.0100 | 12.1360 | 12.6240 | 12.5070 | 12.6140 | 12.1140 | 12.0890 | 12.3800 | 12.6550 | 11.7070 | 12.4150 | 12.8660 | 12.6960 | 11.7940 | 11.6000 | 13.0910 | 12.5880 | 12.3860 | 11.9730 | 12.0300 | 11.7860 | 11.7280 | 12.5580 | 12.0820 | 11.9150 | 12.0490 | 13.1160 | 11.9590 | 11.9200 | 13.0520 | 12.8160 | 11.3670 | 12.4390 | 12.2960 | 12.2570 | 11.8430 | 12.3930 | 13.1930 | 12.9710 | 11.7780 | 12.4250 | 12.4820 | 12.1180 | 11.7140 | 12.4440 | 12.5340 | 12.2380 | 11.7740 | 13.4020 | 12.2260 | 12.0070 | 12.4110 | 12.3190 | 11.9230 | 12.5190 | 12.2180 | 11.8690 | 12.3930 | 12.5980 | 11.9650 | 12.0580 | 12.2200 | 12.2010 | 12.1410 | 11.7930 | 12.0710 | 11.5000 | 11.8940 | 12.3760 | 12.6080 | 11.6920 | 11.7260 | 12.6290 | 12.5930 | 12.1980 | 11.4220 | 12.1750 | 11.4400 | 12.2360 | 12.1390 | 12.2160 | 11.5460 | 11.9620 | 12.3050 | 13.0260 | 12.9590 | 11.9670 | 12.9140 | 12.7870 | 11.8120 | 12.1980 | 11.7340 | 11.3980 | 12.6990 | 12.0530 | 11.3990 | 11.8510 | 11.9380 | 11.6520 | 12.3390 | 11.9860 | 11.9070 | 12.9510 | 12.3370 | 11.9700 | 12.5030 | 11.4600 | 12.4030 | 11.0810 | 12.1400 | 12.8570 | 12.7480 | 12.4910 | 12.2900 | 11.6840 | 12.2390 | 12.7460 | 12.9930 | 11.8740 | 12.2920 | 12.7570 | 12.0000 | 12.2600 | 13.5040 | 12.1340 | 12.4460 | 11.9560 | 11.3820 | 12.1630 | 12.3600 | 12.1700 | 12.6360 | 11.5970 | 11.9270 | 12.8260 | 11.5180 | 12.5330 | 12.1910 | 12.7390 | 11.3840 | 11.3260 | 12.5320 | 13.3590 | 12.4180 | 12.2860 | 12.3100 | 12.2520 | 11.8750 | 11.9810 | 11.9850 | 11.7720 | 12.2170 | 11.8300 | 12.1410 | 11.7350 | 12.0200 | 13.0490 | 12.0210 | 12.8290 | 12.3740 | 12.4250 | 12.6180 | 12.5960 | 12.3220 | 11.9770 | 12.2350 | 12.2490 | 11.9030 | 11.7630 | 12.4440 | 12.4890 | 12.1970 | 11.9910 | 11.9240 | 12.5930 | 12.3230 | 12.5980 | 12.5200 | 12.7660 | 11.5900 | 12.1840 | 11.8480 | 12.5520 | 11.8520 | 12.3190 | 12.2710 | 12.3980 | 12.5130 | 11.9970 | 12.4120 | 12.4420 | 11.8820 | 12.4060 | 11.6840 | 12.3140 | 12.0300 | 12.2510 | 12.6450 | 12.2390 | 12.3550 | 12.4360 | 12.5090 | 12.0180 | 12.4650 | 12.7300 | 12.5710 | 11.8080 | 12.0670 | 12.1990 | 12.3340 | 12.0910 | 11.5800 | 12.4640 | 12.5450 | 12.6740 | 12.8120 | 12.2900 | 13.5830 | 12.1690 | 12.4840 | 12.1420 | 11.9920 | 12.4570 | 12.3050 | 11.9500 | 12.7210 | 12.0860 | 12.0540 | 12.2210 | 12.2850 | 12.4190 | 12.5840 | 12.5590 | 12.4840 | 12.0770 | 11.6050 | 12.1170 | 11.6300 | 12.1040 | 11.9720 | 12.8070 | 11.6470 | 11.9540 | 12.4370 | 11.5800 | 11.9360 | 12.2130 | 12.1830 | 11.9660 | 11.9920 | 12.6290 | 12.1580 | 12.0490 | 12.2270 | 11.9230 | 12.5360 | 11.4380 | 12.6010 | 12.5580 | 12.0410 | 12.3720 | 11.6460 | 12.9080 | 12.3930 | 11.7010 | 11.5540 | 12.0970 | 12.7700 | 12.0040 | 11.8760 | 11.6950 | 11.8050 | 12.7430 | 12.4940 | 11.9980 | 12.1320 | 11.7490 | 11.8100 | 12.1620 | 12.4170 | 12.2070 | 12.0480 | 11.7600 | 12.3210 | 12.1870 | 12.6590 | 11.6870 | 12.3710 | 12.5080 | 12.0160 | 12.0990 | 12.1360 | 12.4780 | 12.4040 | 12.3350 | 12.2530 | 11.7970 | 12.0830 | 12.8890 | 11.6340 | 12.3400 | 12.4510 | 12.3340 | 11.8600 | 11.1610 | 12.5260 | 11.3760 | 11.6800 | 12.8140 | 12.4570 | 12.6080 | 11.9870 | 12.2670 | 12.1560 | 12.4870 | 12.7880 | 12.1540 | 11.9430 | 11.7560 | 12.2410 | 12.0720 | 12.4480 | 12.8120 | 12.0680 | 12.0930 | 12.9530 | 11.6750 | 12.2520 | 12.2320 | 12.2060 | 12.4680 | 11.8180 | 12.7710 | 12.9710 | 12.2650 | 11.7970 | 11.6320 | 12.6380 | 11.7610 | 12.1160 | 11.5980 | 12.3750 | 12.7700 | 13.2770 | 12.5100 | 12.8180 | 12.2010 | 11.8020 | 12.1410 | 12.0780 | 12.2160 | 12.6650 | 11.6280 | 12.2800 | 11.6090 | 12.1810 | 12.6620 | 12.8540 | 12.7160 | 11.6450 | 11.7920 | 11.7530 | 12.8570 | 12.0610 | 12.0500 | 12.0020 | 12.3070 | 12.0720 | 12.5600 | 11.4540 | 12.5310 | 12.5560 | 11.9370 | 12.2340 | 12.2110 | 12.3690 | 11.8140 | 11.4930 | 12.1460 | 11.7670 | 12.1520 | 11.9010 | 13.3930 | 11.7320 | 12.3350 | 12.0440 | 12.3570 | 12.3360 | 12.2430 | 13.7260 | 12.5200 | 11.9950 | 12.0860 | 12.1580 | 13.1920 | 11.6860 | 12.4800 | 12.1340 | 12.0700 | 12.1430 | 13.1390 | 12.0610 | 11.4900 | 12.0700 | 12.2060 | 12.4460 | 11.9890 | 12.1660 | 12.3540 | 12.4720 | 11.7340 | 12.0300 | 11.7260 | 11.7720 | 12.2930 | 11.7810 | 12.5330 | 12.2810 | 12.8400 | 12.7730 | 12.3680 | 12.3220 | 12.3660 | 11.9610 | 12.9070 | 12.2180 | 12.4040 | 12.4060 | 11.7770 | 13.3420 | 12.5120 | 12.3820 | 12.1180 | 11.5000 | 12.4320 | 12.1840 | 12.2550 | 12.4350 | 12.0920 | 13.0270 | 12.2290 | 12.4330 | 12.1300 | 12.1260 | 11.9980 | 12.5240 | 11.9790 | 12.5790 | 12.2860 | 11.9250 | 11.7460 | 12.7580 | 11.5430 | 12.2310 | 12.6490 | 11.9690 | 12.2790 | 11.8680 | 12.5260 | 12.0510 | 11.4980 | 11.9400 | 12.2010 | 10.8930 | 12.0980 | 12.7020 | 11.8900 | 12.1180 | 11.9820 | 12.0390 | 12.2670 | 12.4860 | 12.4040 | 11.5800 | 12.5670 | 11.9240 | 11.8130 | 12.3540 | 12.6830 | 12.0590 | 12.1870 | 12.6830 | 12.1690 | 12.8770 | 12.3970 | 13.0680 | 12.4850 | 12.2030 | 12.0230 | 12.0640 | 12.0650 | 12.8750 | 12.4330 | 11.8930 | 12.4510 | 13.7350 | 12.3760 | 12.3330 | 12.1220 | 12.1660 | 12.3650 | 11.9710 | 11.8020 | 12.8730 | 12.1000 | 12.1360 | 13.0050 | 11.8750 | 11.9890 | 12.4800 | 12.2690 | 12.8150 | 12.6780 | 11.9630 | 12.4260 | 12.2310 | 11.9500 | 12.3130 | 12.6560 | 12.1400 | 12.0570 | 12.5120 | 11.7090 | 12.1730 | 13.0110 | 11.9340 | 12.0440 | 11.5740 | 12.4450 | 12.3760 | 12.3800 | 12.5240 | 12.4490 | 12.5150 | 12.0920 | 12.2280 | 12.4770 | 12.0930 | 12.0280 | 12.1980 | 12.0530 | 11.5340 | 12.5870 | 11.6500 | 12.3250 | 12.3590 | 12.0890 | 12.5900 | 12.5750 | 12.5960 | 11.7330 | 12.0910 | 12.4630 | 12.4550 | 12.4470 | 12.1430 | 11.8000 | 12.0460 | 12.4310 | 11.9810 | 11.9520 | 11.6080 | 11.0380 | 12.0170 | 12.2420 | 11.5930 | 12.1410 | 12.1620 | 12.9410 | 11.9050 | 12.3140 | 12.0050 | 12.4290 | 12.0370 | 12.3870 | 12.2250 | 12.1700 | 12.0940 | 12.2690 | 12.8690 | 11.6390 | 12.1240 | 12.2340 | 11.7300 | 12.5180 | 11.8600 | 12.3670 | 12.2850 | 12.3910 | 11.6910 | 12.0530 | 11.8950 | 11.8500 | 12.4150 | 12.0630 | 12.3800 | 11.9170 | 12.3020 | 12.2980 | 11.7310 | 12.0010 | 12.1750 | 12.2800 | 12.2250 | 11.9320 | 12.5430 | 11.9310 | 12.5660 | 12.3910 | 11.6860 | 12.6740 | 12.0940 | 11.9430 | 12.9540 | 12.0530 | 11.5630 | 12.3180 | 11.5790 | 12.1970 | 12.3130 | 12.1770 | 12.4830 | 12.2960 | 11.6880 | 12.5270 | 12.5380 | 12.5370 | 12.6610 | 11.6720 | 12.1830 | 12.9160 | 12.4140 | 11.4710 | 12.6070 | 11.9660 | 12.0840 | 12.9180 | 11.6700 | 12.3990 | 12.9400 | 12.7520 | 11.7020 | 12.3710 | 12.4930 | 13.7720 | 11.7980 | 11.2420 | 11.8720 | 12.0280 | 12.7550 | 11.8660 | 11.8570 | 12.3250 | 12.8250 | 12.1500 | 12.3740 | 12.0790 | 12.0040 | 11.8860 | 12.1170 | 12.7820 | 12.1480 | 12.5220 | 11.0550 | 12.4960 | 13.0040 | 12.7400 | 12.0370 | 11.1390 | NA | 12.0300 | 12.7230 | 12.3170 | 12.4660 | 12.3180 | 12.9480 | 12.8960 | 11.5970 | 12.1960 | 12.2110 | 12.4210 | 12.6100 | 12.2960 | 12.0730 | 12.1800 | 11.8410 | 12.3260 | 12.6730 | 11.7590 | 12.1460 | 12.3890 | 12.0920 | 12.1710 | 11.6340 | 12.4200 | 11.9010 | 12.4250 | 12.4470 | 12.3590 | 12.8970 | 12.5370 | 12.6080 | 11.9350 | 12.7730 | 12.2100 | 13.0130 | 12.5690 | 12.3270 | 12.4980 | 12.3210 | 12.2100 | 12.0070 | 12.5820 | 12.7770 | 12.1370 | 12.8190 | 12.1980 | 11.7260 | 12.1790 | 12.3840 | 11.9210 | 12.3630 | 12.9910 | 12.4440 | 11.8200 | 12.9270 | 12.3250 | 12.7350 | 12.4890 | 13.0800 | 12.5470 | 12.3820 | 12.0740 | 13.0680 | 12.6980 | 11.8600 | 12.2660 | 12.5540 | 12.2720 | 12.3040 | 12.1490 | 11.7630 | 11.8470 | 11.5420 | 11.8710 | 12.4750 | 12.8820 | 12.3200 | 13.6580 | 12.3890 | 11.8130 | 12.3270 | 12.3990 | 12.0660 | 12.5610 | 11.7970 | 11.9610 | 11.7600 | 11.9010 | 12.1190 | 13.1620 | 12.4420 | 11.9450 | 12.0930 | 12.4470 | 12.6170 | 12.4140 | 11.8400 | 12.4700 | 11.8180 | 12.4040 | 11.5030 | 12.7430 | 12.4780 | 12.7990 | 12.0980 | 11.4040 | 11.7920 | 12.5800 | 12.6960 | 11.7850 | 12.4250 | 11.9610 | 12.1450 | 12.3220 | 12.3370 | 11.8040 | 11.7990 | 12.2420 | 13.2710 | 12.3480 | 12.1410 | 12.8850 | 12.8190 | 12.7920 | 11.6320 | 13.7010 | 12.7380 | 12.9760 | 11.3520 | 11.6221 | 12.4595 | 13.6352 | 11.9043 | 11.1412 | 10.0428 | 12.0990 | 12.1392 | 11.3330 | 11.9625 | 11.4444 | 12.4073 | 11.7195 | 12.2647 | 11.6432 | 11.2547 | 12.3882 | 11.6954 | 12.0137 | 11.4394 | 11.5679 | 12.5207 | 11.5248 | 12.2135 | 12.4022 | 12.0539 | 12.0970 | 11.6733 | 11.9364 | 12.7597 | 11.8772 | 12.1894 | 12.5790 | 12.0980 | 11.2507 | 11.3631 | 12.7285 | 12.1352 | 12.1272 | 11.9223 | 12.0508 | 12.5127 | 9.6302 | 11.4906 | 11.9113 | 12.0870 | 11.7988 | 12.3621 | 12.2155 | 11.8209 | 11.7557 | 12.0790 | 12.3290 | 12.1272 | 11.2727 | 11.2266 | 12.2868 | 11.4856 | 12.3470 | 11.7587 | 11.9063 | 12.1472 | 11.5559 | 12.0268 | 11.5468 | 11.8822 | 12.0780 | 12.5689 | 12.3239 | 15.1010 | 12.1673 | 11.7316 | 12.0800 | 12.0880 | 11.7547 | 11.5197 | 11.8792 | 12.0960 | 11.6934 | 11.7567 | 12.6753 | 11.6723 | 11.3982 | 10.8019 | 11.6362 | 11.7567 | 13.3942 | 11.3731 | 11.5970 | 11.8139 | 12.1101 | 11.8290 | 11.8470 | 11.3199 | 11.3601 | 11.9002 | 11.4675 | 12.0629 | 11.8430 | 11.6241 | 12.4043 | 12.9595 | 11.9796 | 11.4685 | 11.7346 | 11.7878 | 11.5227 | 11.1734 | 11.4535 | 12.37950 |
| ENPP4 | 9.9619 | 8.2837 | 10.3630 | 9.0396 | 9.3834 | 9.5861 | 11.5330 | 8.5668 | 8.2330 | 8.4611 | 8.6374 | 10.7920 | 8.6836 | 9.4660 | 9.1542 | 10.1580 | 11.2050 | 10.1970 | 9.5509 | 9.8792 | 9.4958 | 9.5244 | 9.6544 | 10.9470 | 9.4969 | 9.4054 | 10.6100 | 9.1057 | 10.0640 | 10.7510 | 9.0341 | 10.0150 | 9.0175 | 9.9387 | 10.0000 | 8.6054 | 11.0090 | 9.9718 | 9.9982 | 9.2148 | 9.7448 | 8.8699 | 7.7613 | 9.9222 | 10.5920 | 9.6588 | 9.0098 | 8.7002 | 9.5982 | 9.6765 | 8.3751 | 9.5685 | 10.1910 | 8.6330 | 9.1938 | 9.6787 | 9.9751 | 8.4545 | 8.2539 | 9.8329 | 9.8462 | 11.5530 | 9.8880 | 10.5910 | 8.6440 | 9.5002 | 8.6528 | 10.9000 | 9.7338 | 8.8941 | 9.7988 | 8.7762 | 8.9944 | 9.2401 | 8.7663 | 10.2120 | 9.4263 | 9.0319 | 9.0230 | 9.8572 | 8.5184 | 9.2952 | 9.6985 | 9.5167 | 9.9376 | 9.3040 | 9.4021 | 8.9272 | 9.5090 | 9.3239 | 8.6770 | 9.5619 | 9.6599 | 9.6831 | 9.3371 | 10.1510 | 10.2340 | 9.2015 | 10.6890 | 9.7172 | 9.4252 | 6.6859 | 9.9222 | 9.5773 | 9.0737 | 9.4969 | 8.7398 | 9.7029 | 8.5007 | 9.8396 | 10.9330 | 9.7217 | 9.2489 | 9.7194 | 9.7745 | 9.3999 | 10.6090 | 9.6710 | 8.3487 | 8.9382 | 8.6473 | 8.1272 | 9.2004 | 9.6335 | 9.6159 | 9.7624 | 8.8104 | 8.3465 | 9.7117 | 9.5398 | 9.1641 | 11.3810 | 9.6048 | 8.7443 | 9.9641 | 9.5564 | 8.3905 | 9.2919 | 10.8540 | 9.2963 | 9.9960 | 9.1982 | 9.3834 | 10.6770 | 10.0890 | 10.5990 | 9.9905 | 8.8159 | 10.6810 | 9.5310 | 10.3380 | 9.5718 | 8.5679 | 9.5949 | 8.0523 | 9.5542 | 10.0630 | 9.7437 | 9.3503 | 8.2440 | 9.5696 | 7.8418 | 8.9724 | 10.4490 | 8.2297 | 8.4456 | 9.1376 | 9.7294 | 9.6588 | 8.8489 | 8.8192 | 10.5370 | 9.5365 | 10.2590 | 8.5459 | 9.2919 | 9.9597 | 8.9845 | 9.4186 | 9.8418 | 8.8236 | 10.5120 | 9.1156 | 11.0520 | 10.0140 | 9.9046 | 8.8302 | 8.2781 | 9.4781 | 10.1640 | 8.5492 | 10.0070 | 9.2346 | 7.5288 | 9.1773 | 9.7029 | 8.7057 | 10.1010 | 10.5360 | 10.1000 | 9.2566 | 9.6357 | 8.4379 | 9.5101 | 8.7586 | 8.6153 | 8.8820 | 8.8864 | 9.5431 | 9.5850 | 9.9398 | 8.3068 | 8.8115 | 9.6313 | 9.6137 | 9.2588 | 9.7393 | 9.3911 | 8.3365 | 10.3180 | 10.9290 | 9.9817 | 8.4522 | 9.1189 | 9.4858 | 8.5977 | 9.3481 | 11.5870 | 8.9338 | 9.0693 | 8.7696 | 9.5982 | 9.7261 | 10.2160 | 9.3206 | 7.9046 | 8.4126 | 10.1780 | 9.0142 | 10.0510 | 10.7740 | 7.9509 | 9.1520 | 11.7490 | 10.3480 | 8.1173 | 10.0740 | 9.0495 | 10.0360 | 9.1773 | 9.8781 | 9.9630 | 9.1365 | 9.2489 | 9.8693 | 9.6908 | 10.3320 | 10.3180 | 8.9217 | 9.9046 | 8.7729 | 10.1340 | 9.4539 | 8.6561 | 10.6830 | 10.1940 | 8.5724 | 10.2860 | 9.1839 | 8.8148 | 9.9222 | 9.6809 | 8.0578 | 9.2941 | 9.2115 | 10.7200 | 8.4346 | 10.5460 | 10.5730 | 8.5051 | 10.6050 | 9.4847 | 9.5354 | 9.7371 | 10.8310 | 9.6787 | 8.4886 | 9.4385 | 9.5795 | 10.8180 | 9.6291 | 9.5850 | 8.5635 | 9.1938 | 9.4693 | 9.1630 | 8.4192 | 9.3007 | 10.1670 | 10.1110 | 9.0407 | 8.9613 | 9.0418 | 8.9084 | 10.0280 | 10.7180 | 9.6335 | 8.8082 | 8.5558 | 9.5288 | 9.2963 | 8.7674 | 10.3130 | 10.9290 | 10.1790 | 9.1343 | 9.5707 | 9.8803 | 10.3290 | 9.3889 | 8.9900 | 10.5790 | 9.0363 | 9.9431 | 9.9696 | 9.5740 | 9.2533 | 9.1619 | 9.0219 | 9.6357 | 10.9610 | 9.9277 | 8.4522 | 9.8276 | 9.9543 | 11.1760 | 9.3504 | 9.5400 | 9.3095 | 8.6398 | 9.8362 | 10.0600 | 9.9734 | 10.0280 | 9.7648 | 8.8618 | 8.5589 | 9.2066 | 8.8865 | 10.3720 | 9.5962 | 9.1371 | 9.9524 | 8.0750 | 9.1361 | 9.6905 | 8.7694 | 9.5276 | 8.4208 | 9.6257 | 9.2504 | 8.3122 | 9.5057 | 9.6562 | 9.2533 | 8.8408 | 9.2094 | 9.8695 | 9.7838 | 9.9915 | 9.5981 | 8.9151 | 10.1700 | 9.5152 | 10.1230 | 9.7705 | 9.4962 | 9.5447 | 9.2495 | 8.1017 | 8.0188 | 9.8714 | 9.2923 | 9.4590 | 8.8142 | 8.4074 | 10.0070 | 10.2130 | 9.1437 | 11.7160 | 9.8581 | 9.1418 | 10.0350 | 10.2870 | 10.7650 | 9.5752 | 8.9637 | 11.7770 | 10.6260 | 9.2571 | 10.5080 | 10.5080 | 9.6524 | 10.0700 | 8.3770 | 8.4732 | 9.2571 | 9.1609 | 9.9276 | 8.9027 | 9.7352 | 8.5189 | 11.2300 | 9.1428 | 8.7951 | 10.1950 | 10.6160 | 9.3647 | 8.6294 | 9.5171 | 10.1200 | 9.5685 | 9.8495 | 8.9304 | 9.0247 | 9.4085 | 9.3380 | 10.9410 | 9.0685 | 10.6470 | 9.6705 | 9.4628 | 8.9732 | 9.3009 | 10.4390 | 10.2890 | 9.9695 | 10.5770 | 8.6408 | 9.8819 | 9.3018 | 9.7038 | 8.7808 | 8.7875 | 9.7343 | 9.3114 | 9.4447 | 9.9314 | 9.4657 | 9.1799 | 9.0751 | 10.7890 | 8.6789 | 10.0560 | 9.3647 | 10.6010 | 9.2237 | 9.5095 | 8.8418 | 8.3884 | 9.5533 | 10.6450 | 9.1942 | 9.3666 | 9.7952 | 7.5245 | 9.6724 | 9.1371 | 9.0123 | 9.4952 | 9.8171 | 10.7590 | 9.8600 | 9.8333 | 10.0490 | 9.2352 | 9.8533 | 9.4466 | 9.8124 | 8.9380 | 10.2900 | 9.0942 | 10.6960 | 9.8124 | 8.8646 | 9.1933 | 9.2161 | 10.0030 | 10.3130 | 9.3285 | 9.8838 | 9.9591 | 8.8770 | 8.9704 | 10.5780 | 10.2200 | 9.0580 | 8.5941 | 10.2870 | 10.3410 | 9.4847 | 9.8838 | 8.9980 | 10.3090 | 8.4665 | 9.3076 | 9.9896 | 8.2065 | 11.0470 | 9.0828 | 9.4504 | 9.9695 | 9.0828 | 9.6505 | 10.4170 | 10.2470 | 9.5123 | 9.1237 | 11.0120 | 8.8113 | 8.4465 | 9.4447 | 9.7248 | 9.8248 | 9.3971 | 9.1180 | 9.1694 | 9.8924 | 9.8743 | 9.9915 | 9.7552 | 8.7856 | 9.0818 | 10.2520 | 8.5579 | 9.4438 | 8.8180 | 9.3704 | 9.2209 | 9.5381 | 9.4752 | 9.4295 | 8.7522 | 12.1430 | 8.7551 | 11.1040 | 9.5171 | 9.8438 | 9.1028 | 9.4952 | 8.9780 | 8.5436 | 10.1830 | 9.1523 | 9.5676 | 8.9056 | 8.6541 | 10.0650 | 11.7260 | 8.4408 | 9.5181 | 9.7209 | 8.4903 | 9.7810 | 9.3704 | 8.4951 | 9.4761 | 11.1040 | 9.1199 | 8.9485 | 9.1075 | 9.3409 | 8.1122 | 10.0380 | 9.0018 | 8.7513 | 9.4447 | 9.1466 | 9.5552 | 8.9570 | 11.2510 | 10.9070 | 9.8352 | 8.6246 | 9.3018 | 10.3660 | 10.7780 | 8.7713 | 9.5847 | 9.0837 | 9.3371 | 9.9086 | 10.4590 | 9.6981 | 8.3131 | 8.5541 | 9.7848 | 9.9381 | 9.7771 | 9.4076 | 8.9789 | 8.0074 | 9.3209 | 10.5260 | 8.9485 | 9.1018 | 11.3920 | 9.0370 | 7.9264 | 10.3050 | 8.3208 | 9.7895 | 8.5074 | 9.1799 | 8.5141 | 10.5070 | 11.0660 | 9.1151 | 9.3218 | 9.2142 | 9.8705 | 9.8143 | 9.5181 | 8.7989 | 10.1870 | 9.2304 | 10.1140 | 9.7686 | 9.1190 | 9.2180 | 9.1894 | 9.3095 | 9.8086 | 10.8530 | 9.1056 | 8.2293 | 9.7105 | 9.8838 | 9.6457 | 8.9065 | 10.6900 | 9.2571 | 9.1285 | 10.5100 | 10.8730 | 9.6038 | 9.9000 | 9.8448 | 8.4798 | 10.2310 | 7.3730 | 10.0090 | 10.4570 | 9.4390 | 10.6160 | 9.9676 | 9.1504 | 9.9886 | 8.8446 | 10.2350 | 8.8189 | 9.7962 | 9.6114 | 8.7475 | 10.6250 | 10.3210 | 9.2094 | 9.5009 | 9.3571 | 9.4400 | 9.4161 | 8.4227 | 10.2710 | 8.3331 | 8.7837 | 9.4971 | 10.2610 | 10.0010 | 9.3028 | 8.4608 | 9.6343 | 9.5409 | 8.9351 | 10.3650 | 8.8608 | 9.6714 | 9.0675 | 9.7200 | 9.4419 | 8.4122 | 10.0600 | 9.1580 | 9.1656 | 9.2314 | 9.3457 | 8.6379 | 9.7962 | 10.4310 | 9.7124 | 7.6140 | 8.3703 | 9.8133 | 8.2598 | 9.0104 | 9.4523 | 9.1799 | 9.4962 | 8.3312 | 9.5019 | 9.4190 | 9.3799 | 10.0220 | 8.7561 | 8.1550 | 9.6990 | 11.4740 | 11.1630 | 9.7495 | 9.5304 | 9.8467 | 10.3370 | 9.9038 | 9.2933 | 9.8162 | 10.0830 | 10.5770 | 8.4589 | 9.2790 | 8.5560 | 9.4666 | 10.4540 | 8.2179 | 7.1263 | 10.5170 | 8.5408 | 11.4490 | 8.5551 | 8.8570 | 9.9334 | 9.2695 | 11.2870 | 8.2588 | 8.7637 | 9.2275 | 9.1390 | 9.5228 | 9.9514 | 10.1680 | 12.3720 | 9.7933 | 9.6724 | 11.1740 | 9.3104 | 9.3819 | 9.3447 | 9.3599 | 10.0170 | 10.6200 | 10.0470 | 8.9227 | 10.0440 | 8.0474 | 9.8714 | 8.9561 | 8.6246 | 9.1199 | 10.0220 | 9.1999 | 8.9904 | 9.8972 | 9.1609 | 9.4590 | 8.7332 | 8.2874 | 11.2390 | 9.4133 | 7.5702 | 9.2247 | 9.1047 | 10.0960 | 10.5090 | 9.5019 | 9.4342 | 12.2290 | 10.3950 | 9.9743 | 9.0818 | 8.7246 | 8.9923 | 9.1618 | 9.5019 | 9.5657 | 8.6503 | 10.6720 | 9.4771 | 8.8856 | 9.0066 | 10.1060 | 9.3866 | 9.4142 | 9.6047 | 10.3890 | 8.8294 | 9.0599 | 9.5809 | 8.6484 | 8.6846 | 10.3850 | 10.5900 | 9.8029 | 8.9799 | 8.7961 | 9.3085 | 8.8704 | 9.4838 | 9.5181 | 9.9448 | 9.5866 | 10.8130 | 9.7333 | 9.7943 | 10.2480 | 8.5941 | 9.6047 | 9.9314 | 7.9398 | 10.2240 | 8.6427 | 9.3685 | 9.8819 | 7.9531 | 8.0807 | 8.4255 | 9.0666 | 9.5771 | 10.2590 | 10.3700 | 8.8751 | 9.1771 | 10.6450 | 10.0980 | 8.2341 | 10.9270 | 9.3599 | 9.7257 | 9.2018 | 10.1320 | 8.6808 | 8.1960 | 7.2044 | 9.0132 | 8.8875 | 9.7562 | 8.5208 | 9.6771 | 8.8999 | 8.7141 | 9.3638 | 9.9724 | 8.6970 | 7.7045 | 9.0885 | 8.9542 | 9.4019 | 10.2830 | 10.2490 | 9.4485 | 8.9942 | 8.6065 | 7.9426 | 9.5333 | 9.8800 | 10.2610 | 9.4400 | 9.8552 | 11.1970 | 9.7133 | 9.5161 | 8.5617 | 9.3180 | 11.1192 | 9.5523 | 9.5504 | 8.9265 | 8.9656 | 9.2409 | 8.9018 | 8.2350 | 9.9067 | 10.0362 | 9.1323 | 11.3459 | 9.7819 | 10.0096 | 9.8181 | 9.1218 | 9.5657 | 9.7076 | 8.4579 | 9.9095 | 9.8419 | 9.1675 | 10.7230 | 9.4276 | 8.8360 | 10.6220 | 8.7903 | 9.1742 | 9.5200 | 9.4247 | 10.3677 | 9.5019 | 9.9753 | 8.0845 | 10.3458 | 9.5828 | 10.1601 | 9.7343 | 8.5970 | 8.1340 | 9.1409 | 8.3064 | 9.2075 | 9.0685 | 10.3115 | 9.9191 | 10.5106 | 9.2771 | 9.8657 | 9.3390 | 8.9865 | 9.5952 | 10.2591 | 8.1045 | 11.1802 | 9.7543 | 10.3048 | 9.6019 | 11.1535 | 10.4277 | 9.0494 | 9.7667 | 10.2105 | 9.5962 | 8.5036 | 9.3218 | 9.3352 | 9.6714 | 10.0981 | 8.2541 | 9.9772 | 8.8522 | 9.4190 | 9.0599 | 10.2143 | 10.7782 | 9.2561 | 8.3826 | 10.3782 | 11.4688 | 9.4190 | 10.2582 | 10.0553 | 9.5276 | 9.7857 | 8.5760 | 7.9131 | 8.5198 | 10.3972 | 11.9184 | 7.6864 | 10.2877 | 9.5123 | 9.7638 | 9.9762 | 8.5598 | 9.0466 | 9.7095 | 9.2590 | 9.2409 | 8.1502 | 8.6398 | 10.2591 | 9.6676 | 9.7648 | 9.0342 | 9.46150 |
| SEMA3F | 8.2284 | 7.3826 | 9.6703 | 7.2874 | 8.5348 | 6.7404 | 7.9285 | 7.0881 | 7.7268 | 7.6107 | 8.0332 | 7.5197 | 7.8423 | 7.4957 | 6.7541 | 6.9762 | 8.4864 | 7.2402 | 8.8658 | 7.8243 | 7.8196 | 6.6183 | 7.3359 | 6.0772 | 6.6213 | 6.9529 | 6.5375 | 8.0488 | 8.4911 | 7.1216 | 8.2523 | 7.6131 | 7.0654 | 6.5943 | 9.2244 | 6.7487 | 7.4664 | 7.7705 | 6.9529 | 7.8423 | 8.7617 | 7.7489 | 9.1029 | 7.2958 | 7.6873 | 8.2236 | 7.1839 | 5.9874 | 7.5951 | 7.6382 | 7.5532 | 6.7464 | 5.7288 | 7.8459 | 8.2493 | 6.6320 | 6.3782 | 7.7896 | 7.0349 | 7.3323 | 8.2912 | 8.0297 | 6.7888 | 7.1767 | 7.5981 | 6.8469 | 6.5428 | 7.2916 | 7.3916 | 9.8564 | 7.9925 | 6.5566 | 5.4984 | 7.2851 | 7.3928 | 6.7571 | 7.2785 | 6.0143 | 6.2753 | 6.7703 | 7.0384 | 7.8249 | 9.0837 | 7.7417 | 8.6659 | 7.6077 | 7.0217 | 6.7709 | 6.1556 | 8.2781 | 7.4048 | 6.6817 | 6.2250 | 6.3046 | 7.5502 | 7.3192 | 7.3736 | 7.2509 | 7.4772 | 8.2936 | 6.1095 | 6.6901 | 8.7737 | 7.0097 | 6.8768 | 8.1338 | 7.0875 | 7.5245 | 7.0995 | 7.1749 | 7.9231 | 8.1619 | 7.4030 | 6.8391 | 8.7042 | 8.5600 | 7.8423 | 7.9770 | 7.7765 | 7.5245 | 6.9942 | 7.7699 | 7.0145 | 7.5592 | 6.5835 | 6.7817 | 6.7362 | 9.2549 | 8.6581 | 7.1635 | 6.3423 | 6.8547 | 7.4383 | 6.7912 | 8.4977 | 7.1360 | 7.5197 | 7.9746 | 7.7100 | 6.9870 | 8.5462 | 7.1426 | 7.2084 | 6.4501 | 6.0999 | 6.4459 | 7.7328 | 8.1625 | 6.5662 | 8.2613 | 6.6727 | 7.4060 | 6.2681 | 8.5468 | 5.9658 | 6.3758 | 7.1600 | 7.6759 | 7.2856 | 7.5394 | 8.0608 | 6.8732 | 6.7577 | 5.7138 | 6.9834 | 6.2328 | 8.6246 | 7.9465 | 6.9169 | 6.1161 | 8.0189 | 7.6125 | 6.6284 | 6.5333 | 6.4944 | 6.7475 | 7.2150 | 7.7435 | 6.9954 | 7.5215 | 8.7365 | 7.5514 | 7.6753 | 7.3329 | 8.4600 | 7.1905 | 8.6551 | 8.0925 | 6.4070 | 7.1971 | 7.1773 | 6.9451 | 9.2567 | 6.4567 | 7.1468 | 8.0428 | 7.0941 | 5.8539 | 6.6021 | 7.0319 | 7.3976 | 7.7687 | 7.3952 | 7.6238 | 7.7412 | 8.0051 | 7.0444 | 8.6061 | 7.2497 | 5.8701 | 6.1077 | 7.5981 | 6.9648 | 8.1889 | 8.4588 | 7.5819 | 6.9648 | 6.2914 | 7.4754 | 6.6709 | 5.4433 | 7.9937 | 7.0534 | 7.1582 | 8.4283 | 8.2781 | 6.3088 | 7.4389 | 7.2629 | 6.1771 | 5.5091 | 6.4991 | 6.9696 | 7.3497 | 6.7039 | 6.5758 | 6.6446 | 7.0570 | 7.0480 | 6.8972 | 6.2621 | 8.1961 | 7.7717 | 7.6382 | 7.8447 | 8.1206 | 8.9203 | 6.8074 | 7.4700 | 7.2396 | 6.6045 | 6.6655 | 7.3353 | 7.6723 | 6.5111 | 8.7647 | 6.3322 | 7.3431 | 7.0522 | 7.5712 | 6.7679 | 7.6813 | 7.2713 | 7.8579 | 6.3178 | 7.9423 | 7.3323 | 8.5648 | 6.6560 | 7.1294 | 7.1546 | 7.4772 | 6.1705 | 7.5855 | 7.2432 | 8.1673 | 7.0079 | 8.8269 | 8.0392 | 6.9020 | 8.1464 | 7.6891 | 6.7158 | 6.7260 | 6.7799 | 8.2236 | 7.8662 | 7.1151 | 7.4688 | 6.9948 | 6.1861 | 7.6208 | 7.5574 | 7.2515 | 8.9431 | 6.9038 | 6.6344 | 7.2108 | 6.2513 | 6.6638 | 7.1402 | 7.2491 | 7.8782 | 7.2928 | 8.2068 | 8.2870 | 6.0820 | 6.8290 | 6.1095 | 7.3156 | 8.1733 | 7.4850 | 6.7601 | 7.6765 | 7.2467 | 7.2964 | 7.9500 | 7.0295 | 7.5933 | 6.9110 | 6.5584 | 6.1526 | 7.0043 | 7.7926 | 7.5981 | 6.7386 | 7.5430 | 7.7842 | 8.4971 | 7.1659 | 8.4457 | 6.8409 | 7.0522 | 6.7637 | 8.7079 | 7.2095 | 8.1703 | 7.3381 | 7.2298 | 6.9080 | 7.3312 | 9.1311 | 6.7655 | 6.5622 | 6.1915 | 8.8125 | 7.8130 | 8.3736 | 6.9864 | 6.1537 | 6.0486 | 7.6664 | 5.6904 | 7.2680 | 8.0177 | 8.9785 | 7.7835 | 6.2192 | 7.2418 | 8.0324 | 7.2482 | 7.5852 | 6.6765 | 8.5442 | 8.1947 | 7.7148 | 6.6599 | 7.5719 | 7.2478 | 7.4004 | 7.5733 | 7.3815 | 8.1818 | 7.4958 | 8.4986 | 7.2579 | 8.0431 | 8.5258 | 8.9831 | 6.7355 | 7.7222 | 8.0924 | 7.0182 | 7.3409 | 6.6567 | 6.4917 | 7.9306 | 7.1795 | 7.4197 | 7.8015 | 6.9407 | 7.2782 | 6.7355 | 9.0324 | 9.1578 | 7.0435 | 7.8798 | 7.1473 | 6.8388 | 8.7249 | 7.2989 | 9.2611 | 7.5414 | 7.0108 | 7.1385 | 7.8600 | 6.3142 | 7.1671 | 7.3003 | 7.3672 | 8.0781 | 7.6364 | 6.9204 | 7.7586 | 7.1731 | 5.7803 | 5.9730 | 7.0818 | 7.3506 | 7.1532 | 6.5147 | 6.8600 | 8.7079 | 7.3123 | 7.7535 | 7.0269 | 7.6862 | 8.2123 | 6.8471 | 7.3068 | 7.3593 | 6.4271 | 6.8918 | 6.7189 | 5.9061 | 6.7222 | 6.5419 | 9.3201 | 8.5497 | 6.6396 | 6.1947 | 7.5018 | 7.8176 | 5.9278 | 7.1606 | 6.8964 | 7.6530 | 7.5202 | 9.2385 | 8.0873 | 6.9864 | 8.0071 | 6.5714 | 6.3455 | 7.6622 | 7.5023 | 6.3686 | 6.6300 | 7.8222 | 7.8268 | 6.1196 | 6.7291 | 7.4326 | 7.0149 | 8.1311 | 8.0417 | 6.5816 | 9.1394 | 8.4248 | 7.9476 | 8.0975 | 5.7794 | 6.8872 | 7.9315 | 6.9435 | 7.7673 | 9.5815 | 8.7152 | 7.3934 | 6.5327 | 6.3063 | 6.1588 | 8.6747 | 6.6765 | 7.3930 | 6.8254 | 7.6078 | 6.3248 | 6.9094 | 7.1477 | 6.6373 | 7.2561 | 6.9476 | 7.0440 | 8.7973 | 6.6807 | 6.9725 | 7.2293 | 6.7480 | 7.7637 | 7.2828 | 6.2593 | 7.0168 | 6.1754 | 8.3736 | 6.8190 | 6.2132 | 8.7715 | 6.9034 | 7.4884 | 7.1975 | 6.9333 | 7.2611 | 7.1763 | 7.0329 | 6.9642 | 7.0726 | 6.4976 | 6.4225 | 8.6793 | 7.7756 | 6.9287 | 7.5018 | 5.7918 | 7.1901 | 7.5322 | 6.9389 | 6.7060 | 6.8444 | 6.6267 | 8.1081 | 8.3188 | 7.2321 | 7.7443 | 7.2455 | 6.4184 | 7.7480 | 7.7641 | 6.4497 | 6.1191 | 8.9425 | 7.3409 | 7.2256 | 6.4479 | 6.6401 | 6.8789 | 7.4322 | 7.0348 | 6.9877 | 6.7747 | 7.3022 | 7.9246 | 5.4497 | 7.5866 | 6.7692 | 7.6267 | 8.4442 | 7.5202 | 6.4110 | 7.3363 | 7.6304 | 8.3377 | 6.9084 | 7.8711 | 7.4654 | 7.0260 | 7.6060 | 6.6014 | 7.3510 | 7.8600 | 8.0191 | 7.5331 | 7.9472 | 6.8268 | 6.4119 | 8.2865 | 6.7591 | 7.2436 | 8.5082 | 6.8102 | 8.2473 | 6.6254 | 7.0629 | 8.2496 | 7.8088 | 6.2312 | 8.5737 | 10.0480 | 7.1648 | 8.8024 | 7.0799 | 6.9840 | 8.4714 | 6.9619 | 6.5299 | 7.1242 | 7.1030 | 7.2367 | 6.8278 | 7.6189 | 7.5451 | 6.3151 | 7.3211 | 7.8171 | 7.5995 | 7.5645 | 7.2330 | 7.4870 | 9.0652 | 5.9486 | 8.0163 | 8.3911 | 7.5539 | 6.8609 | 7.1214 | 6.6807 | 7.4658 | 7.0758 | 7.5880 | 7.3658 | 7.2994 | 6.8540 | 6.7803 | 7.3303 | 6.5700 | 6.9817 | 7.2261 | 7.1698 | 8.0371 | 6.4645 | 8.2731 | 7.2851 | 7.1182 | 6.5050 | 6.7010 | 8.5059 | 7.1399 | 6.4852 | 7.0237 | 7.8503 | 5.8739 | 8.0753 | 6.8845 | 8.2164 | 7.4248 | 8.1311 | 7.0601 | 8.6184 | 7.3607 | 7.3349 | 8.3427 | 6.5548 | 6.9887 | 7.8116 | 9.7337 | 6.8010 | 7.4681 | 7.1560 | 6.9393 | 7.7664 | 8.3174 | 7.8909 | 7.1399 | 6.9946 | 8.9264 | 6.2160 | 7.5705 | 7.4797 | 6.8545 | 7.1330 | 7.9633 | 8.2288 | 7.4442 | 7.3768 | 7.2478 | 7.3838 | 7.9831 | 6.6839 | 7.1915 | 7.3796 | 8.4654 | 7.6816 | 6.3921 | 6.7083 | 7.3372 | 6.6258 | 8.0131 | 8.7789 | 7.9817 | 8.9144 | 8.7245 | 9.0062 | 7.2196 | 7.8462 | 7.8356 | 6.9292 | 6.7909 | 7.3483 | 7.7826 | 7.7480 | 7.4165 | 6.1035 | 6.9412 | 7.3215 | 6.8139 | 6.8799 | 6.2302 | 6.8167 | 8.2726 | 7.9937 | 9.1767 | 7.0878 | 7.0726 | 8.0495 | 6.8900 | 5.9453 | 6.4502 | 8.2786 | 8.8383 | 9.4898 | 6.5604 | 6.5156 | 8.7996 | 8.3584 | 6.9075 | 7.0965 | 6.4552 | 7.5926 | 7.2616 | 9.4165 | 6.0039 | 6.5931 | 7.4921 | 7.8854 | 8.7152 | 6.2653 | 6.5299 | 8.6097 | 8.6507 | 6.9338 | 7.8324 | 9.4432 | 6.6987 | 7.4778 | 6.6904 | 6.6622 | 7.3450 | 7.2501 | 7.1302 | 8.1850 | 8.0251 | 7.7508 | 8.6276 | 6.6406 | 7.3243 | 8.7383 | 6.3340 | 8.2247 | 6.2289 | 7.0855 | 7.5069 | 9.0412 | 7.7046 | 8.4082 | 6.2376 | 7.7019 | 6.8282 | 6.6655 | 7.5059 | 7.6401 | 7.7203 | 6.9831 | 7.1648 | 7.4571 | 6.1731 | 7.1016 | 7.8688 | 6.8702 | 6.8937 | 7.0638 | 6.5650 | 7.1343 | 7.0896 | 6.5456 | 8.1726 | 8.1532 | 7.9140 | 8.2210 | 6.4986 | 6.5253 | 6.5304 | 7.0265 | 7.2888 | 5.9195 | 7.4580 | 8.1915 | 6.5594 | 7.8015 | 6.6645 | 7.4953 | 7.3930 | 7.1579 | 6.2528 | 7.7973 | 6.7531 | 7.8222 | 6.8554 | 8.9854 | 6.0956 | 6.1362 | 6.4792 | 5.9864 | 7.6244 | 7.2538 | 7.9536 | 8.0753 | 6.9333 | 7.0620 | 6.3119 | 5.4723 | 7.2381 | 8.1749 | 8.2325 | 6.7291 | 7.3460 | 6.3340 | 6.5908 | 6.0776 | 7.0089 | 8.0269 | 7.6968 | 7.2021 | 6.6904 | 7.0338 | 5.4857 | 7.2206 | 7.8125 | 7.6544 | 8.0785 | 7.2164 | 6.8444 | 7.8052 | 6.9656 | 6.9232 | 8.4635 | 7.4857 | 7.6383 | 8.3040 | 6.8660 | 8.3363 | 7.2856 | 8.3828 | 7.3524 | 7.0080 | 6.7254 | 6.5156 | 7.7558 | 8.8305 | 6.0726 | 7.2496 | 8.6069 | 5.9541 | 8.3473 | 7.1044 | 6.1800 | 7.4548 | 7.7872 | 5.5078 | 6.9375 | 7.1625 | 6.6899 | 7.0915 | 7.1546 | 6.0629 | 8.0320 | 6.2671 | 8.1731 | 7.0117 | 6.1643 | 7.3054 | 8.1809 | 8.1527 | 7.9462 | 6.5387 | 5.8448 | 6.6645 | 6.9660 | 7.0878 | 8.4390 | 7.8826 | 6.9121 | 8.0439 | 8.1311 | 6.8973 | 8.6106 | 7.0831 | 8.1638 | 8.7318 | 6.4833 | 7.3745 | 6.3635 | 7.5788 | 5.7973 | 6.7065 | 6.5516 | 7.3298 | 6.9296 | 7.5257 | 5.9508 | 6.6189 | 7.2076 | 6.1228 | 7.4321 | 6.5142 | 8.3662 | 7.8959 | 8.0942 | 6.5663 | 8.6931 | 7.3427 | 6.6530 | 7.4644 | 7.8286 | 7.9937 | 6.5834 | 8.0707 | 5.6636 | 7.6013 | 6.8088 | 7.5801 | 8.4105 | 7.5986 | 7.7521 | 5.8374 | 7.2620 | 7.4363 | 7.8522 | 8.4722 | 6.3063 | 7.4455 | 5.9624 | 7.1915 | 5.4271 | 8.2758 | 7.9485 | 5.9831 | 7.6345 | 6.9375 | 7.6558 | 7.0924 | 7.2205 | 6.6839 | 6.9342 | 5.8969 | 5.2528 | 8.2671 | 8.3593 | 7.2759 | 8.7281 | 7.0430 | 7.4833 | 7.5871 | 8.0942 | 7.5414 | 5.9435 | 6.3100 | 6.2998 | 5.8596 | 6.8706 | 7.4875 | 7.8946 | 7.7300 | 6.5765 | 8.7747 | 7.6857 | 7.9149 | 7.5405 | 5.3593 | 6.5368 | 7.3229 | 8.5534 | 6.6355 | 7.3031 | 6.3561 | 6.7678 | 6.6908 | 6.95785 |
| CFTR | 4.0713 | 4.0962 | 4.8268 | 4.9354 | 5.3265 | 5.6654 | 5.1613 | 4.6548 | 5.3867 | 6.0285 | 6.8503 | 5.7076 | 5.4804 | 6.5983 | 6.3916 | 4.3960 | 4.8982 | 6.2166 | 5.2842 | 6.1477 | 5.9788 | 5.7926 | 6.0577 | 5.3842 | 4.9025 | 5.6765 | 5.5462 | 5.2197 | 7.4009 | 6.6467 | 5.2464 | 7.4102 | 5.2979 | 5.7212 | 4.8156 | 5.1787 | 6.7616 | 5.2265 | 5.3656 | 4.9962 | 5.5716 | 4.9075 | 7.0645 | 6.6083 | 7.2085 | 5.9782 | 4.8963 | 4.9087 | 5.2669 | 6.5605 | 5.0235 | 5.8783 | 4.4121 | 6.5276 | 6.0595 | 5.2582 | 5.4686 | 5.2178 | 4.5021 | 6.4593 | 7.6436 | 6.9962 | 4.6654 | 7.3891 | 6.4847 | 5.1874 | 3.6617 | 4.6685 | 4.8311 | 5.0018 | 5.8671 | 4.8702 | 5.1104 | 5.6846 | 5.9900 | 5.3494 | 5.6213 | 6.4816 | 4.8926 | 6.3264 | 4.4115 | 7.3351 | 6.4841 | 6.0757 | 4.4500 | 6.5648 | 5.2675 | 5.5238 | 5.3836 | 5.7057 | 6.1595 | 4.4264 | 4.6623 | 5.5381 | 5.1899 | 6.4599 | 6.2712 | 7.9925 | 4.9714 | 5.3054 | 4.8547 | 5.1409 | 6.9043 | 5.6914 | 5.2805 | 7.8007 | 6.3246 | 5.9360 | 6.0341 | 5.9354 | 5.1036 | 6.9372 | 5.8485 | 5.2091 | 7.3935 | 6.8510 | 4.6008 | 5.9397 | 6.0291 | 5.9441 | 5.1278 | 4.7237 | 5.3662 | 6.6294 | 5.2029 | 5.6263 | 5.1247 | 5.7492 | 4.9298 | 5.3891 | 4.4854 | 5.7734 | 9.0427 | 5.0502 | 6.7281 | 5.1415 | 4.8746 | 4.7225 | 5.8559 | 4.8721 | 5.3072 | 4.8404 | 6.2973 | 5.5356 | 4.9683 | 5.5164 | 7.0483 | 6.7001 | 5.6604 | 5.0577 | 5.1700 | 6.0316 | 5.0297 | 5.1669 | 5.7498 | 5.3935 | 6.4053 | 8.8770 | 6.3817 | 5.8280 | 5.3656 | 4.6163 | 5.0595 | 5.2563 | 6.2557 | 5.1291 | 6.5710 | 5.3054 | 5.0403 | 4.7498 | 5.3562 | 5.0813 | 4.7721 | 5.5375 | 4.7740 | 5.1260 | 6.3507 | 5.1862 | 6.1812 | 6.6318 | 5.5462 | 6.1464 | 5.4574 | 5.1874 | 5.3811 | 6.6560 | 5.1402 | 4.3563 | 5.3525 | 6.3302 | 5.2911 | 4.6579 | 5.8137 | 5.5698 | 5.1378 | 5.9335 | 5.4643 | 4.7678 | 4.0515 | 5.1229 | 7.3817 | 5.1930 | 5.2569 | 4.7194 | 6.0614 | 6.4090 | 5.1440 | 6.1408 | 4.5009 | 5.0794 | 5.3445 | 5.8112 | 5.3978 | 5.9217 | 5.1284 | 5.8398 | 5.8553 | 5.3891 | 5.2184 | 7.6281 | 4.9491 | 6.4556 | 6.1433 | 6.3295 | 5.2222 | 6.7864 | 5.1396 | 6.7746 | 5.9354 | 4.9379 | 4.4134 | 5.6176 | 5.1800 | 5.7814 | 5.1936 | 4.1167 | 5.4748 | 5.5530 | 6.3488 | 5.0757 | 5.5003 | 6.1644 | 4.9937 | 5.7672 | 6.7169 | 5.8975 | 5.2408 | 5.0546 | 6.7938 | 5.2749 | 5.0198 | 5.3724 | 5.3202 | 6.0931 | 6.8081 | 5.4084 | 5.3792 | 5.5468 | 5.3482 | 9.9298 | 5.1415 | 5.5474 | 5.1235 | 5.8230 | 5.4512 | 4.6027 | 5.7144 | 5.6120 | 4.5667 | 8.1036 | 5.9552 | 6.1998 | 5.1887 | 5.6343 | 5.7368 | 5.4065 | 5.7914 | 5.4587 | 4.4115 | 5.9447 | 6.5623 | 7.0006 | 6.6430 | 4.9143 | 5.0862 | 5.2991 | 5.5356 | 5.0782 | 5.6803 | 5.3358 | 4.7591 | 6.4779 | 6.0558 | 6.0068 | 6.6635 | 5.4400 | 5.0651 | 5.9925 | 5.9962 | 5.3022 | 6.2966 | 4.8206 | 5.0471 | 6.3972 | 4.6194 | 7.1359 | 5.4376 | 5.8851 | 5.7641 | 7.2681 | 4.2824 | 5.4612 | 5.9428 | 6.8714 | 9.2023 | 6.1489 | 5.8280 | 5.5238 | 6.8131 | 5.1762 | 4.9596 | 5.1272 | 5.8280 | 7.2513 | 6.7827 | 5.3985 | 5.3693 | 4.9739 | 6.5158 | 5.4667 | 6.5878 | 4.3358 | 5.1520 | 6.0604 | 5.5084 | 5.8937 | 5.8928 | 4.8178 | 5.2205 | 5.9210 | 4.9344 | 4.7951 | 5.1248 | 5.7434 | 5.5904 | 5.8500 | 4.9026 | 5.8901 | 5.4200 | 5.9693 | 6.4431 | 5.0674 | 4.7112 | 6.3319 | 5.0875 | 4.7914 | 5.3353 | 5.7334 | 6.2171 | 5.2096 | 5.0101 | 5.5029 | 5.3799 | 5.5585 | 4.5227 | 5.7789 | 5.6769 | 5.0009 | 8.2177 | 5.3417 | 6.5715 | 5.6660 | 5.6751 | 5.1777 | 5.5740 | 7.1217 | 5.5257 | 5.3954 | 5.4027 | 6.1707 | 5.5311 | 4.9399 | 6.0595 | 6.2253 | 5.5639 | 5.7261 | 5.0993 | 5.3034 | 5.2414 | 6.1042 | 5.3644 | 6.0677 | 6.3538 | 5.3699 | 5.4091 | 5.9693 | 8.1175 | 7.0498 | 9.9376 | 4.9627 | 5.8218 | 4.8816 | 5.8218 | 5.9766 | 6.0213 | 4.8452 | 5.3198 | 5.2451 | 5.5867 | 5.2870 | 5.6177 | 6.5196 | 6.0686 | 5.4054 | 6.4640 | 5.1012 | 5.4847 | 6.0723 | 5.6851 | 5.1804 | 4.8734 | 6.9942 | 4.6156 | 5.4674 | 4.9180 | 6.9733 | 5.8418 | 5.0602 | 8.2058 | 4.9463 | 5.0565 | 5.0146 | 6.0531 | 8.1439 | 5.8691 | 5.8463 | 5.6368 | 4.6876 | 5.3526 | 4.2002 | 5.2788 | 5.1385 | 7.3695 | 5.2178 | 5.9101 | 8.7807 | 6.0149 | 5.4810 | 4.7112 | 6.3237 | 5.2023 | 7.2229 | 5.6359 | 5.1294 | 6.2745 | 6.0012 | 4.6539 | 5.7543 | 6.6061 | 6.0668 | 4.6921 | 6.6535 | 5.7288 | 4.8625 | 5.6696 | 6.5815 | 5.5885 | 5.8017 | 5.3225 | 5.4419 | 5.1021 | 5.3936 | 5.0219 | 5.5384 | 5.8172 | 4.7777 | 4.8160 | 5.7170 | 5.3499 | 5.6441 | 7.1873 | 5.7270 | 4.9517 | 6.1452 | 4.7586 | 7.3695 | 5.3234 | 6.5050 | 5.4610 | 6.4913 | 5.4765 | 6.0623 | 5.9912 | 6.5852 | 5.3271 | 5.5676 | 5.9693 | 4.8388 | 5.4528 | 5.4109 | 5.5566 | 5.2761 | 5.3034 | 5.3963 | 5.7607 | 5.9657 | 6.1953 | 5.4072 | 5.7707 | 6.1288 | 5.9593 | 5.0274 | 5.5712 | 6.0276 | 6.2845 | 5.4318 | 3.9906 | 5.9466 | 8.9255 | 5.2797 | 5.9848 | 5.7024 | 4.5791 | 5.1330 | 5.2496 | 5.3544 | 5.3453 | 5.1768 | 4.9864 | 5.7516 | 4.7951 | 5.0356 | 4.8306 | 5.3990 | 5.0173 | 6.2964 | 4.3806 | 6.3201 | 6.3419 | 5.4410 | 5.9602 | 5.7379 | 6.1415 | 5.7361 | 4.6074 | 5.2050 | 5.5075 | 5.4519 | 5.5858 | 5.9065 | 5.5157 | 5.3007 | 9.0002 | 5.9912 | 6.3811 | 5.2496 | 6.4695 | 5.6587 | 5.5412 | 5.7798 | 6.3337 | 4.8279 | 4.5846 | 4.6411 | 5.6742 | 4.9964 | 5.4801 | 12.5270 | 6.1032 | 5.8883 | 5.8454 | 5.4683 | 6.3784 | 5.3143 | 5.8054 | 5.2961 | 5.4127 | 5.8145 | 5.4173 | 5.6068 | 5.6651 | 6.0677 | 4.9700 | 5.0720 | 5.2442 | 5.4464 | 5.3972 | 4.7368 | 5.0848 | 5.5211 | 5.8181 | 11.7820 | 5.7079 | 5.3152 | 7.9608 | 8.2213 | 5.4419 | 6.2016 | 5.8299 | 6.5487 | 5.9511 | 6.0158 | 5.6878 | 5.7908 | 6.6744 | 5.6678 | 5.9611 | 5.6687 | 5.3553 | 7.9772 | 5.1795 | 5.1868 | 5.2752 | 5.6259 | 6.0030 | 6.9177 | 5.0438 | 6.1124 | 6.0950 | 5.7625 | 5.4127 | 5.5913 | 5.8810 | 5.4619 | 6.2044 | 5.9484 | 9.2826 | 5.0583 | 6.9860 | 6.1060 | 6.8412 | 5.8008 | 5.0993 | 5.7598 | 5.0182 | 5.7215 | 5.9511 | 7.3850 | 6.2645 | 6.2672 | 4.8333 | 6.1078 | 5.7789 | 4.9800 | 4.5810 | 5.6988 | 5.9247 | 5.1194 | 5.7334 | 6.2071 | 5.4983 | 5.1786 | 5.2369 | 5.5439 | 5.0529 | 6.3529 | 4.8552 | 6.4522 | 5.0711 | 7.2866 | 5.7534 | 5.9147 | 5.0793 | 6.2162 | 4.9727 | 5.3863 | 5.1631 | 5.9912 | 5.0948 | 7.3377 | 6.1980 | 4.5236 | 5.7234 | 5.4473 | 5.3389 | 5.0028 | 4.7568 | 5.5885 | 5.2670 | 5.8573 | 5.9912 | 5.5166 | 6.0814 | 6.0841 | 5.8054 | 5.0419 | 5.0893 | 5.1431 | 8.5812 | 5.5648 | 5.5740 | 6.0021 | 5.2588 | 4.4662 | 6.3875 | 6.6735 | 5.6605 | 5.5676 | 6.5806 | 4.8251 | 5.7662 | 5.5776 | 5.9529 | 5.8500 | 6.1652 | 6.2144 | 4.5873 | 4.5236 | 6.0131 | 5.2861 | 4.8497 | 5.7470 | 6.5059 | 5.9220 | 6.5496 | 6.7892 | 6.4431 | 6.0577 | 5.0237 | 5.2223 | 5.1786 | 7.6064 | 5.0474 | 5.2433 | 4.9609 | 5.8564 | 5.4829 | 4.9235 | 5.7443 | 4.9827 | 5.3371 | 5.6969 | 4.7103 | 5.0337 | 5.0319 | 5.9429 | 6.4485 | 4.2831 | 5.6450 | 5.2424 | 6.0304 | 5.8181 | 7.0807 | 5.9365 | 5.5120 | 5.6550 | 5.1895 | 5.2533 | 5.1148 | 5.5239 | 5.7953 | 4.9991 | 5.5576 | 5.3599 | 6.1069 | 5.0173 | 5.2187 | 5.5648 | 5.4218 | 4.5254 | 5.1267 | 6.1461 | 4.9108 | 5.4829 | 5.3644 | 4.9791 | 4.9773 | 4.9654 | 5.0966 | 5.3098 | 4.8279 | 5.4364 | 4.9927 | 4.7131 | 5.6423 | 5.7653 | 4.6466 | 4.9026 | 7.6137 | 6.0112 | 5.0037 | 7.2566 | 5.1904 | 6.6280 | 4.7550 | 5.3936 | 4.6557 | 5.6569 | 5.7097 | 4.7641 | 5.6714 | 4.8789 | 5.5020 | 6.2818 | 5.2551 | 5.8035 | 5.2405 | 5.4118 | 5.7680 | 7.9644 | 6.2854 | 5.5157 | 10.6000 | 5.4783 | 4.9900 | 5.8290 | 4.4580 | 5.0775 | 5.1658 | 5.3407 | 7.8451 | 4.9162 | 4.5199 | 5.2332 | 5.1358 | 5.0957 | 5.0756 | 5.3316 | 8.9756 | 4.9089 | 5.6432 | 4.9845 | 4.8315 | 5.1367 | 5.4045 | 5.4938 | 4.9272 | 5.4701 | 4.9681 | 5.4364 | 4.7632 | 5.5412 | 5.6569 | 4.9891 | 4.8907 | 4.7067 | 4.9982 | 5.4583 | 5.4173 | 4.8442 | 6.0258 | 5.6450 | 5.0428 | 6.6298 | 8.4063 | 5.4519 | 5.6304 | 4.9627 | 4.6848 | 4.8324 | 5.9001 | 4.9372 | 5.0629 | 6.0386 | 4.8187 | 5.6022 | 4.8361 | 5.6578 | 5.5794 | 6.1889 | 5.4036 | 5.6177 | 5.1321 | 5.5293 | 5.1230 | 5.5056 | 5.3462 | 5.8828 | 6.0231 | 5.6323 | 5.5147 | 4.9499 | 6.2636 | 5.4810 | 5.4865 | 5.9611 | 4.6129 | 6.3957 | 5.1786 | 5.6651 | 4.5664 | 5.7653 | 6.0267 | 3.7538 | 4.7641 | 4.2430 | 4.5491 | 5.6660 | 5.9411 | 4.7513 | 5.9721 | 4.9472 | 5.2223 | 9.7172 | 7.2949 | 6.3820 | 4.2703 | 4.7167 | 5.0702 | 4.3733 | 4.7987 | 5.2606 | 4.2230 | 7.0134 | 4.5527 | 4.3951 | 4.3778 | 5.4291 | 4.8488 | 5.6277 | 4.4881 | 5.0702 | 4.1938 | 5.2141 | 5.4774 | 4.3232 | 5.0921 | 5.1258 | 5.2579 | 6.0267 | 4.7504 | 5.7999 | 6.3101 | 4.7058 | 4.7368 | 5.3745 | 4.6748 | 4.1200 | 3.9169 | 5.7908 | 5.5749 | 4.5436 | 5.1513 | 4.4498 | 4.8178 | 4.2430 | 4.0052 | 4.9436 | 5.2324 | 4.6557 | 4.5591 | 8.3370 | 5.2770 | 5.8673 | 5.6897 | 4.8834 | 5.0638 | 5.1331 | 3.8586 | 5.4911 | 6.9004 | 4.4134 | 4.3942 | 5.8518 | 6.2955 | 5.3808 | 4.7386 | 5.3235 | 4.1574 | 6.1761 | 5.5257 | 4.8342 | 4.2876 | 4.2357 | 4.7422 | 4.3405 | 4.5855 | 4.4106 | 6.1215 | 5.4656 | 4.3532 | 4.5591 | 4.7322 | 4.0845 | 5.6514 | 5.7571 | 5.6232 | 4.5673 | 4.4890 | 6.0869 | 4.1911 | 4.6320 | 4.3660 | 4.4279 | 7.2775 | 3.8467 | 8.97860 |
| ANKIB1 | 7.9097 | 7.9659 | 8.8805 | 8.9959 | 8.3236 | 8.0768 | 8.2322 | 8.7116 | 8.5584 | 7.9947 | 8.7798 | 9.0457 | 8.2037 | 8.8229 | 7.8828 | 8.3584 | 8.2547 | 8.4082 | 8.1865 | 8.2652 | 8.5127 | 8.1479 | 8.1839 | 9.0873 | 8.8401 | 8.4270 | 9.3637 | 8.1663 | 8.7719 | 8.1884 | 7.6142 | 8.3322 | 8.6356 | 8.3360 | 7.9786 | 8.5517 | 8.7727 | 7.3494 | 8.7405 | 8.2622 | 8.3154 | 8.3667 | 8.6640 | 8.6611 | 8.3573 | 8.0446 | 8.4390 | 8.0060 | 8.8079 | 8.6551 | 8.0888 | 7.8858 | 8.9573 | 8.2082 | 8.1738 | 8.2772 | 8.8408 | 8.1277 | 8.3846 | 8.4217 | 8.9139 | 8.4629 | 8.2360 | 8.8244 | 8.6607 | 8.5865 | 8.4727 | 8.8723 | 8.1311 | 8.0839 | 8.3427 | 8.1614 | 8.3258 | 8.4521 | 8.4131 | 7.7045 | 8.2180 | 8.8139 | 8.3146 | 8.8423 | 8.8120 | 8.2536 | 8.6906 | 8.1667 | 8.6858 | 8.0034 | 8.1895 | 7.5813 | 8.1225 | 8.5258 | 8.5652 | 8.7487 | 8.1667 | 8.0869 | 8.0086 | 8.2786 | 10.9380 | 7.9015 | 8.2708 | 8.1985 | 9.3023 | 8.3648 | 7.9745 | 8.1502 | 8.6341 | 9.0532 | 8.9045 | 7.7607 | 9.0502 | 8.1198 | 8.2086 | 8.7097 | 9.1229 | 7.8509 | 8.6401 | 8.6371 | 8.5723 | 8.1243 | 8.4037 | 8.9809 | 8.6543 | 8.6004 | 7.9805 | 8.2562 | 8.6753 | 8.1565 | 8.5577 | 8.2191 | 7.9191 | 8.2768 | 8.6281 | 8.1846 | 8.2955 | 8.7052 | 7.9880 | 8.8715 | 8.6831 | 8.8116 | 8.6667 | 9.5322 | 8.2700 | 8.4678 | 8.5880 | 9.5236 | 8.2326 | 8.0112 | 8.3082 | 8.5888 | 9.3086 | 8.2034 | 7.7891 | 7.9195 | 8.6150 | 7.9685 | 9.2764 | 8.4779 | 8.0944 | 7.9846 | 8.9685 | 7.8768 | 8.0981 | 7.7861 | 8.1981 | 8.3637 | 8.0992 | 7.7266 | 8.6925 | 8.5914 | 7.8569 | 9.1768 | 7.7970 | 8.0041 | 8.6446 | 8.2206 | 8.7348 | 8.9670 | 8.7948 | 8.2944 | 8.2079 | 8.2045 | 7.6794 | 8.1858 | 7.7790 | 8.9760 | 8.2352 | 8.2547 | 8.3858 | 8.0461 | 8.2127 | 7.4666 | 8.5052 | 7.9300 | 8.7026 | 7.9352 | 7.9509 | 8.5026 | 7.6607 | 8.2854 | 8.2049 | 8.2704 | 8.7974 | 8.0064 | 7.9625 | 8.8854 | 8.4730 | 8.3622 | 8.0580 | 8.1345 | 8.4011 | 8.5120 | 8.2517 | 8.4805 | 9.2607 | 8.0944 | 8.4824 | 7.8562 | 8.6603 | 8.4221 | 7.9397 | 8.4700 | 9.2236 | 7.9344 | 8.5112 | 8.5655 | 8.4034 | 8.5390 | 8.6307 | 8.2217 | 7.9940 | 8.1292 | 9.4794 | 8.1925 | 8.0442 | 8.5854 | 7.8974 | 7.9981 | 7.8888 | 7.9187 | 8.7326 | 8.1757 | 8.6307 | 8.4498 | 7.8539 | 8.7401 | 7.8831 | 8.2513 | 7.7640 | 8.0861 | 8.4079 | 8.3970 | 8.3041 | 8.2034 | 7.9577 | 8.2835 | 8.5060 | 8.1423 | 9.0322 | 7.8255 | 8.2434 | 8.5985 | 8.0693 | 7.8547 | 8.1719 | 8.7082 | 7.4056 | 8.3670 | 8.4483 | 8.0285 | 8.6603 | 8.8667 | 8.5655 | 8.2948 | 8.0236 | 8.0532 | 8.4296 | 8.2697 | 8.2719 | 8.4464 | 8.4056 | 8.3169 | 8.1217 | 8.1423 | 8.6614 | 8.1453 | 8.0026 | 7.7341 | 8.1715 | 8.7787 | 8.5891 | 8.6828 | 8.4079 | 9.0948 | 9.1877 | 8.4678 | 8.6258 | 8.2610 | 8.6974 | 12.8660 | 8.6071 | 8.5453 | 9.5435 | 7.8906 | 8.2131 | 8.3985 | 7.5745 | 8.5240 | 8.6487 | 8.3011 | 9.0476 | 8.5655 | 7.8764 | 7.7558 | 8.2434 | 8.4442 | 8.8393 | 8.2783 | 7.9532 | 8.2985 | 8.4461 | 8.2090 | 8.5075 | 8.1547 | 8.4064 | 8.6577 | 8.5607 | 7.7809 | 8.2742 | 8.4056 | 8.3401 | 8.3816 | 8.9667 | 8.3434 | 8.2772 | 8.0002 | 8.4328 | 8.7634 | 8.0682 | 9.1403 | 8.3733 | 7.8103 | 8.4753 | 8.0984 | 8.9448 | 8.4668 | 8.7710 | 8.2061 | 8.4271 | 9.1932 | 8.6822 | 8.3620 | 8.2958 | 8.3506 | 8.5565 | 8.0077 | 8.7294 | 8.9117 | 7.8557 | 9.2036 | 8.0824 | 8.3724 | 8.5906 | 8.4167 | 8.6737 | 8.2184 | 8.6255 | 7.9444 | 8.8626 | 9.2867 | 8.4337 | 7.9029 | 8.4678 | 8.0417 | 8.4385 | 8.5783 | 8.1324 | 8.2118 | 8.2873 | 8.1456 | 8.5244 | 9.4804 | 8.8683 | 7.9010 | 8.8125 | 9.2546 | 8.7228 | 10.7330 | 8.9741 | 7.9671 | 7.9794 | 8.5830 | 8.0918 | 8.1985 | 8.5443 | 9.0043 | 8.7426 | 9.3878 | 8.2382 | 8.4668 | 8.6246 | 8.3846 | 9.1441 | 8.4838 | 8.3827 | 8.3043 | 8.5150 | 8.1730 | 8.5159 | 8.4035 | 8.6208 | 8.0399 | 8.4045 | 8.3912 | 9.2027 | 8.8749 | 9.0959 | 9.0477 | 9.3028 | 8.9316 | 8.0417 | 7.8793 | 8.2892 | 8.1995 | 8.5310 | 7.9690 | 8.2448 | 8.1230 | 8.6633 | 8.9854 | 7.9766 | 8.7436 | 8.2524 | 8.4621 | 8.2278 | 8.4215 | 8.8881 | 8.3195 | 8.5858 | 8.5452 | 8.5480 | 8.2467 | 8.4319 | 9.0402 | 8.4111 | 9.3434 | 8.5490 | 9.0562 | 8.3516 | 8.4149 | 8.7719 | 8.3714 | 7.9359 | 9.1885 | 8.9155 | 8.3468 | 8.1636 | 8.5301 | 7.9860 | 8.0937 | 8.6576 | 8.0550 | 9.5276 | 8.9533 | 9.0270 | 7.8198 | 7.9605 | 6.6570 | 8.5575 | 7.9161 | 8.4508 | 7.7036 | 8.0285 | 9.4454 | 8.3308 | 8.1664 | 8.5792 | 8.5688 | 8.3251 | 7.9350 | 7.4759 | 8.5358 | 8.3799 | 8.4385 | 8.1116 | 7.7631 | 8.6557 | 8.2543 | 8.0115 | 8.7426 | 8.6661 | 8.0465 | 8.3138 | 8.8097 | 8.5216 | 7.8339 | 8.2864 | 8.8229 | 8.6765 | 8.6841 | 9.3406 | 8.2089 | 8.3015 | 8.6283 | 8.4838 | 8.5660 | 8.0143 | 8.3119 | 8.3393 | 8.4668 | 8.7644 | 8.5216 | 8.5537 | 8.3223 | 8.1721 | 8.5008 | 7.5147 | 8.6350 | 9.2055 | 8.3393 | 8.2694 | 8.4073 | 8.3450 | 8.2581 | 9.0052 | 8.4781 | 8.4611 | 8.1201 | 8.8872 | 9.1762 | 9.2489 | 8.8135 | 9.0468 | 7.7697 | 8.8890 | 9.1687 | 7.9898 | 9.1601 | 7.6091 | 8.3865 | 9.0260 | 8.8182 | 8.4309 | 8.1995 | 8.8673 | 9.2423 | 8.5830 | 9.3103 | 8.2599 | 9.1082 | 8.2779 | 8.7049 | 7.6214 | 7.8415 | 8.3884 | 8.3563 | 8.1636 | 8.0408 | 8.4064 | 8.3242 | 8.3790 | 8.4007 | 8.3516 | 8.4149 | 8.6406 | 7.4551 | 8.6227 | 8.6642 | 9.0657 | 9.9073 | 9.0194 | 8.3365 | 8.5320 | 8.0956 | 8.4970 | 8.5972 | 8.5263 | 7.7187 | 8.3865 | 7.8972 | 7.7669 | 8.9675 | 8.6642 | 8.9911 | 8.8484 | 7.5430 | 8.5811 | 9.0024 | 8.5462 | 8.2269 | 8.1334 | 8.2571 | 8.3025 | 8.9174 | 8.4838 | 7.9019 | 8.8588 | 8.0578 | 8.2949 | 8.3450 | 8.4848 | 8.3487 | 8.5339 | 9.3576 | 8.8994 | 8.5802 | 8.4356 | 8.6935 | 8.5225 | 8.2193 | 8.0323 | 9.3103 | 8.2722 | 8.5395 | 8.1891 | 8.2779 | 8.4385 | 9.2593 | 8.8957 | 8.1721 | 8.2618 | 8.4536 | 8.2004 | 8.4706 | 8.9117 | 8.0408 | 8.0465 | 8.2184 | 7.9029 | 8.6510 | 7.4608 | 8.5613 | 8.1315 | 8.8796 | 8.4016 | 8.7351 | 8.5395 | 8.5301 | 8.7407 | 8.6963 | 8.8975 | 8.1192 | 7.9237 | 8.1787 | 9.1592 | 8.5537 | 8.3827 | 7.7329 | 8.5263 | 8.3638 | 7.8330 | 8.3062 | 7.4079 | 7.9775 | 9.1687 | 8.9986 | 8.3195 | 8.8494 | 7.4410 | 8.3185 | 7.7489 | 8.1466 | 7.8755 | 8.8021 | 8.9344 | 7.8840 | 8.3242 | 8.7955 | 8.3525 | 8.4526 | 8.3043 | 8.1409 | 8.8692 | 8.9316 | 8.5792 | 8.6605 | 8.4045 | 7.7300 | 8.7785 | 8.4111 | 7.0716 | 7.3238 | 8.2099 | 7.9076 | 8.5707 | 8.3676 | 8.2552 | 9.1753 | 8.4753 | 7.3267 | 7.8472 | 8.0125 | 8.6765 | 8.3355 | 8.0040 | 8.6359 | 8.4564 | 8.4564 | 7.9492 | 7.8982 | 8.4234 | 8.1192 | 8.0984 | 9.5720 | 8.7511 | 8.0153 | 8.3809 | 8.7483 | 7.8122 | 8.1258 | 8.0918 | 8.1693 | 7.8944 | 8.8550 | 8.0077 | 8.7936 | 7.7971 | 7.9407 | 8.7124 | 8.7398 | 7.8453 | 7.9596 | 9.2518 | 9.1715 | 7.9813 | 8.9845 | 8.2694 | 8.6170 | 7.9463 | 8.2023 | 8.0465 | 8.3006 | 8.8749 | 8.1683 | 8.1523 | 8.3648 | 7.9548 | 8.0899 | 8.4167 | 8.9013 | 8.9013 | 9.3018 | 8.8078 | 7.6658 | 11.7010 | 7.9520 | 8.2089 | 9.3944 | 8.4970 | 9.0591 | 9.0581 | 8.2269 | 8.4309 | 9.2168 | 7.4145 | 8.0323 | 8.2505 | 7.9133 | 7.3153 | 7.8594 | 8.3705 | 8.3553 | 8.1834 | 7.7678 | 9.1979 | 7.7867 | 8.3128 | 7.8547 | 8.0975 | 7.6960 | 7.5666 | 7.9123 | 8.2486 | 8.2137 | 8.6737 | 8.1853 | 8.9306 | 8.3346 | 7.9274 | 7.7395 | 8.7134 | 8.3922 | 8.8475 | 9.2792 | 7.6752 | 8.9372 | 8.7115 | 8.5254 | 7.6941 | 7.6601 | 8.1419 | 8.3818 | 8.2184 | 8.1268 | 7.9511 | 8.9797 | 8.5292 | 7.9870 | 8.9523 | 8.5915 | 8.8494 | 8.3941 | 7.9312 | 9.0515 | 8.4791 | 8.2930 | 8.6123 | 7.7140 | 7.8953 | 8.1938 | 7.9104 | 8.6179 | 7.3626 | 7.9671 | 8.1551 | 8.3601 | 8.3232 | 8.1674 | 8.6350 | 7.7725 | 8.6368 | 8.4536 | 8.4479 | 7.6563 | 7.7744 | 7.8632 | 7.8764 | 7.5298 | 7.7234 | 8.2061 | 7.5430 | 8.4045 | 8.1995 | 8.8182 | 8.5688 | 8.1041 | 8.7662 | 8.1636 | 8.2864 | 7.8094 | 8.4385 | 8.2099 | 7.7527 | 7.7999 | 7.8519 | 8.0805 | 8.1201 | 8.1674 | 8.0361 | 7.9303 | 7.2681 | 7.7848 | 8.7275 | 8.2240 | 8.2297 | 7.9152 | 7.7858 | 8.9495 | 8.0682 | 8.2429 | 8.2146 | 8.5736 | 7.3201 | 7.9256 | 7.5987 | 7.6091 | 8.3846 | 8.2023 | 8.8626 | 8.5046 | 8.5339 | 7.5647 | 8.4120 | 8.1815 | 7.8207 | 8.5235 | 8.2004 | 8.5188 | 8.3997 | 8.3506 | 8.0096 | 8.3828 | 8.6359 | 8.4904 | 7.7933 | 8.3081 | 8.3497 | 8.5207 | 7.9964 | 7.8802 | 8.2099 | 9.4785 | 7.9123 | 8.8513 | 7.4703 | 8.4168 | 8.4536 | 8.0984 | 9.0506 | 8.5518 | 8.4782 | 8.6142 | 8.4300 | 7.7480 | 8.6888 | 9.0478 | 8.1910 | 8.5745 | 8.3648 | 8.3147 | 8.1409 | 7.8236 | 8.1655 | 8.5915 | 7.9671 | 7.9048 | 8.1844 | 7.9624 | 8.4272 | 8.0446 | 7.7829 | 7.6412 | 7.6016 | 8.0276 | 8.2231 | 8.3761 | 8.4961 | 8.2807 | 8.4640 | 8.1570 | 8.8966 | 7.8368 | 7.8330 | 8.2581 | 7.8056 | 8.9108 | 8.3204 | 8.3157 | 8.0512 | 7.3002 | 8.5065 | 8.6491 | 8.0503 | 8.3138 | 8.4753 | 8.0578 | 7.8906 | 8.7918 | 7.5543 | 8.1305 | 8.5339 | 8.6114 | 8.0115 | 8.7625 | 8.1834 | 9.2291 | 8.9344 | 7.7499 | 7.5836 | 8.1135 | 8.1551 | 7.7848 | 8.2439 | 8.2184 | 9.0855 | 7.8547 | 8.4442 | 8.2108 | 8.6557 | 7.7026 | 8.3705 | 8.5670 | 7.9454 | 8.1787 | 8.4555 | 8.2732 | 7.9879 | 8.2515 | 8.0521 | 7.8774 | 8.3950 | 8.3828 | 7.8632 | 7.3191 | 8.4224 | 8.3327 | 8.1532 | 7.7839 | 7.94265 |
| CYP51A1 | 9.9704 | 9.9086 | 10.3710 | 10.8150 | 9.5464 | 9.2960 | 11.0760 | 10.7000 | 11.4010 | 9.5541 | 10.5390 | 10.2800 | 10.1020 | 10.3940 | 9.4959 | 10.0950 | 10.3890 | 10.7610 | 10.6260 | 9.9818 | 10.1660 | 10.9120 | 11.4850 | 10.8260 | 9.8355 | 9.7623 | 10.6810 | 10.9060 | 9.8669 | 10.2620 | 9.4794 | 10.5590 | 9.6242 | 9.7834 | 10.3630 | 10.3450 | 9.9009 | 9.6577 | 8.3175 | 10.0520 | 10.0420 | 10.5790 | 9.7638 | 9.7710 | 9.7149 | 9.2728 | 10.5550 | 9.3908 | 9.5067 | 10.6250 | 8.9147 | 9.4408 | 10.3820 | 9.9431 | 10.7760 | 9.9550 | 10.1630 | 9.9117 | 10.8360 | 10.4950 | 10.5290 | 9.3151 | 9.4614 | 9.9400 | 9.5680 | 9.0033 | 10.1840 | 10.7020 | 9.9668 | 9.9158 | 9.5747 | 9.6690 | 11.5760 | 9.4428 | 9.6355 | 8.7169 | 9.8932 | 10.1230 | 10.9000 | 9.7035 | 10.4800 | 10.2580 | 10.6830 | 9.6324 | 10.3720 | 9.3568 | 10.0940 | 9.0482 | 10.4310 | 11.0300 | 10.3170 | 10.5120 | 10.2370 | 10.0330 | 9.4877 | 10.7720 | 12.9680 | 10.6320 | 9.9014 | 9.8664 | 10.8960 | 9.7226 | 10.4100 | 9.6757 | 9.4944 | 10.0980 | 10.1760 | 9.4356 | 10.4920 | 10.4580 | 9.9333 | 10.2410 | 9.9184 | 10.5600 | 9.9200 | 10.4820 | 9.7489 | 9.4578 | 10.0290 | 11.8740 | 11.0670 | 9.8962 | 10.1850 | 10.4340 | 10.7220 | 9.2445 | 10.0870 | 10.1430 | 9.6773 | 10.2030 | 10.2340 | 9.5067 | 10.8410 | 11.1870 | 9.6273 | 10.0420 | 9.9308 | 10.1610 | 10.8890 | 9.6840 | 9.9514 | 10.4520 | 9.9261 | 10.9580 | 10.2940 | 9.5923 | 9.2697 | 9.8947 | 10.0680 | 10.0250 | 9.6675 | 9.4938 | 10.8400 | 9.6963 | 11.6360 | 11.0120 | 9.1280 | 9.5088 | 10.2570 | 10.2160 | 9.7051 | 10.1600 | 10.0250 | 9.9215 | 9.4985 | 11.1710 | 10.4890 | 10.3140 | 11.5530 | 9.8092 | 10.4770 | 9.8221 | 10.3590 | 8.7282 | 9.8622 | 10.7600 | 10.5960 | 10.2470 | 9.7056 | 9.6031 | 9.2403 | 10.3980 | 9.3666 | 10.1840 | 10.0190 | 10.3060 | 8.9832 | 11.0370 | 9.6160 | 9.3728 | 10.4280 | 9.8901 | 10.5960 | 9.4557 | 9.2445 | 9.5165 | 9.5485 | 10.1850 | 10.6550 | 9.3759 | 10.7390 | 10.0200 | 10.1330 | 10.8530 | 9.8288 | 10.0490 | 9.9947 | 9.8803 | 10.5460 | 10.5170 | 9.1203 | 10.3800 | 10.0150 | 10.2040 | 10.4660 | 9.6149 | 10.3050 | 9.7118 | 9.0981 | 9.2218 | 10.4730 | 9.4227 | 10.5130 | 10.2250 | 11.3510 | 10.5400 | 9.7262 | 9.9390 | 9.6711 | 10.7420 | 9.7087 | 10.4770 | 9.2646 | 10.2900 | 10.5700 | 9.7211 | 10.0540 | 9.8087 | 9.8004 | 9.1167 | 10.9000 | 10.4430 | 9.5170 | 10.1560 | 10.5690 | 11.2840 | 10.2650 | 10.0670 | 9.6103 | 10.0060 | 9.6788 | 9.2280 | 9.6726 | 9.0275 | 9.4660 | 11.0320 | 10.2140 | 10.2830 | 9.5933 | 10.2400 | 9.7716 | 9.1115 | 10.1550 | 10.6260 | 10.2040 | 10.2940 | 9.6422 | 10.1130 | 10.8960 | 10.5190 | 10.5060 | 10.6860 | 10.7170 | 10.2600 | 10.1950 | 10.0120 | 11.4170 | 10.0430 | 10.4260 | 10.4950 | 9.4088 | 9.8303 | 9.6938 | 10.1790 | 10.0500 | 9.7803 | 9.8081 | 9.8674 | 10.0290 | 10.8780 | 10.6380 | 10.8460 | 10.4910 | 9.6288 | 10.9500 | 10.7370 | 8.9745 | 15.8580 | 10.0820 | 10.1030 | 10.2900 | 9.9220 | 10.3540 | 9.8190 | 9.5608 | 10.1080 | 9.4877 | 9.7391 | 11.4470 | 10.0210 | 9.6793 | 10.5730 | 10.1230 | 11.2090 | 10.3690 | 9.2944 | 9.5335 | 10.5370 | 10.3200 | 10.0010 | 10.0320 | 9.9076 | 9.6175 | 10.3710 | 10.1190 | 10.0630 | 10.4390 | 10.6170 | 10.1970 | 9.4078 | 10.4020 | 10.1370 | 11.0320 | 9.1648 | 10.5780 | 9.6273 | 9.9913 | 10.4740 | 10.6040 | 10.4460 | 9.9382 | 9.7995 | 10.2270 | 10.1950 | 10.0830 | 10.4190 | 10.3540 | 11.9800 | 10.2390 | 9.2848 | 9.9628 | 9.8487 | 10.4630 | 11.9320 | 10.6900 | 11.3080 | 9.5977 | 10.6370 | 10.0430 | 10.1350 | 10.5680 | 10.2940 | 9.8929 | 9.5968 | 10.1160 | 10.0810 | 9.7178 | 10.7690 | 11.8270 | 10.3750 | 10.3010 | 10.4450 | 10.8640 | 10.1870 | 9.6961 | 10.3790 | 8.4455 | 10.0560 | 10.6010 | 9.8073 | 10.8740 | 9.5948 | 10.2370 | 10.8520 | 9.6450 | 13.0170 | 10.4740 | 9.1451 | 10.2340 | 9.8861 | 9.0113 | 10.2070 | 10.3920 | 10.7350 | 10.2950 | 10.6180 | 9.7572 | 9.8989 | 10.7100 | 10.8660 | 10.5730 | 9.3655 | 10.3770 | 11.1580 | 10.4490 | 10.1050 | 8.8076 | 10.0790 | 11.7310 | 9.5653 | 9.9638 | 9.6902 | 10.3040 | 10.6710 | 10.6260 | 10.6440 | 9.9992 | 10.5700 | 9.5643 | 9.3527 | 9.8969 | 10.8650 | 10.6120 | 10.8740 | 10.9270 | 9.6893 | 10.7950 | 10.9860 | 9.8369 | 10.5020 | 10.4750 | 9.4560 | 9.5682 | 9.7768 | 10.7730 | 9.8772 | 11.2440 | 9.6617 | 9.6853 | 10.7800 | 11.3120 | 9.8310 | 9.8703 | 10.6290 | 9.3478 | 11.2670 | 9.9205 | 9.9057 | 10.4300 | 10.6340 | 9.3301 | 10.8180 | 10.1730 | 9.4895 | 9.5082 | 10.4160 | 8.9877 | 11.0630 | 10.8220 | 9.7512 | 9.9933 | 10.1140 | 10.5960 | 9.8241 | 9.1756 | 8.6993 | 10.3560 | 9.5623 | 10.9540 | 9.7394 | 9.1402 | 10.2570 | 9.7985 | 9.8496 | 9.6322 | 10.8220 | 9.8516 | 10.6010 | 9.6450 | 9.7099 | 10.9020 | 10.2460 | 9.7522 | 9.8428 | 10.8430 | 9.9982 | 9.5151 | 10.9920 | 9.2396 | 9.5141 | 10.3400 | 9.8989 | 10.6020 | 10.2410 | 10.4800 | 10.5570 | 8.7397 | 9.4836 | 10.5620 | 10.2370 | 10.2940 | 9.2642 | 9.3990 | 10.9980 | 9.9451 | 9.9264 | 10.3100 | 10.3200 | 10.2810 | 10.8300 | 10.9770 | 10.0200 | 9.5544 | 9.6538 | 10.1670 | 10.0590 | 9.7542 | 9.8024 | 10.2280 | 10.8580 | 9.8359 | 9.0073 | 10.9630 | 10.8190 | 10.1370 | 10.6650 | 10.9840 | 11.1660 | 10.5670 | 9.2071 | 11.0340 | 9.2819 | 10.0930 | 10.9020 | 9.7522 | 10.3020 | 9.3311 | 10.0800 | 9.4246 | 9.2947 | 9.6096 | 9.5869 | 11.3190 | 9.7640 | 10.3620 | 10.6740 | 10.2190 | 10.4650 | 9.3488 | 10.2880 | 8.6777 | 8.7515 | 9.6243 | 11.0820 | 9.3311 | 11.0160 | 10.5360 | 9.3931 | 9.0752 | 11.0500 | 9.1540 | 10.2460 | 10.9040 | 8.6285 | 9.9815 | 10.8500 | 10.4280 | 11.4880 | 10.7530 | 10.9300 | 10.4620 | 10.2090 | 10.1470 | 10.5220 | 9.4629 | 10.7270 | 10.1400 | 8.7544 | 9.2022 | 10.2890 | 11.1070 | 10.7550 | 10.5090 | 10.2100 | 10.2980 | 10.0060 | 10.3150 | 9.7522 | 9.7916 | 10.4600 | 10.5390 | 9.9894 | 10.9040 | 9.3508 | 11.6780 | 9.9746 | 10.3980 | 10.7540 | 10.3980 | 9.5426 | 11.2930 | 10.3040 | 9.2651 | 10.4150 | 10.2300 | 10.3440 | 10.8120 | 10.1140 | 10.6090 | 9.5121 | 9.9215 | 9.8644 | 10.0010 | 10.5860 | 10.6760 | 10.5350 | 11.0350 | 10.2860 | 9.8605 | 9.9481 | 9.0034 | 9.6243 | 10.7450 | 11.0170 | 9.2957 | 9.7129 | 9.3911 | 11.0380 | 9.6322 | 10.2730 | 10.0500 | 9.8516 | 9.4718 | 10.9100 | 10.3190 | 10.5850 | 10.5520 | 10.8090 | 10.0850 | 10.6380 | 9.8467 | 9.8201 | 10.1210 | 9.5495 | 10.2440 | 10.3820 | 10.3980 | 9.4492 | 9.3271 | 10.3100 | 11.3980 | 9.6253 | 10.7850 | 10.9750 | 10.3700 | 9.7719 | 9.6027 | 9.0861 | 9.4236 | 10.5550 | 10.4630 | 10.8570 | 9.6745 | 9.0989 | 9.7257 | 9.9805 | 10.3500 | 10.3020 | 9.0585 | 11.8820 | 10.3430 | 10.5470 | 10.5370 | 10.4400 | 10.4330 | 9.1018 | 11.7890 | 9.7385 | 8.8194 | 9.0211 | 12.8120 | 9.6912 | 9.6027 | 9.4934 | 9.4206 | 10.0800 | 9.8388 | 9.5171 | 10.1430 | 9.8260 | 10.9250 | 10.0920 | 9.6519 | 10.8920 | 10.1250 | 9.7955 | 10.3080 | 9.4147 | 9.4669 | 9.5112 | 9.6952 | 10.2850 | 10.9350 | 9.8703 | 10.1560 | 11.2020 | 9.1235 | 11.3930 | 9.5466 | 10.8190 | 10.3520 | 10.8680 | 10.5110 | 10.8670 | 9.3695 | 9.5112 | 10.0430 | 10.1690 | 9.5131 | 10.0170 | 10.7380 | 10.8360 | 9.7434 | 11.0620 | 9.6194 | 10.5660 | 10.5300 | 9.5121 | 9.6637 | 9.8910 | 10.5200 | 10.3290 | 10.2140 | 10.2130 | 10.0330 | 9.2642 | 10.4060 | 10.4480 | 9.5003 | 9.7670 | 10.7830 | 10.2470 | 13.7990 | 10.1960 | 9.8851 | 11.1900 | 10.8130 | 10.6250 | 11.7750 | 10.2570 | 10.5280 | 10.9590 | 10.6040 | 9.0979 | 9.2327 | 10.3860 | 9.4767 | 10.2900 | 10.0480 | 10.1020 | 10.0180 | 10.3930 | 10.8580 | 9.7424 | 9.2032 | 9.3773 | 9.1254 | 10.4790 | 9.8900 | 9.2474 | 9.8851 | 10.0960 | 10.1440 | 9.6332 | 8.7328 | 9.1579 | 9.8870 | 9.6312 | 9.8044 | 10.3110 | 10.6240 | 9.2779 | 8.7377 | 10.3660 | 10.4260 | 10.8030 | 9.2022 | 10.1250 | 11.0600 | 9.7562 | 9.8152 | 10.3590 | 9.6391 | 10.5770 | 10.3590 | 9.9195 | 10.8940 | 10.3520 | 10.0710 | 8.9178 | 10.7870 | 10.1560 | 10.7310 | 10.3140 | 10.7090 | 9.0920 | 10.1820 | 9.9166 | 8.8420 | 9.5997 | 9.4265 | 10.2150 | 9.9510 | 10.0780 | 9.9244 | 9.6430 | 11.6570 | 9.8123 | 9.9963 | 9.2976 | 9.9116 | 9.8319 | 9.3980 | 9.2091 | 9.5604 | 8.3894 | 9.3950 | 10.1670 | 9.3990 | 10.2280 | 9.9776 | 10.1560 | 9.5407 | 10.4500 | 10.0330 | 10.5250 | 10.7340 | 9.7512 | 9.7257 | 10.6590 | 9.8605 | 10.4900 | 9.6656 | 9.8004 | 9.7286 | 9.7995 | 9.2120 | 9.7778 | 9.7237 | 10.2780 | 10.0240 | 11.2190 | 11.0480 | 9.7503 | 9.2868 | 10.0390 | 10.5070 | 9.9766 | 9.2179 | 9.7257 | 9.6647 | 11.3360 | 9.7434 | 9.8418 | 9.0910 | 9.9854 | 10.1110 | 9.7945 | 10.7630 | 10.4000 | 9.6538 | 10.1330 | 9.1156 | 10.3560 | 10.0660 | 9.5653 | 10.4530 | 9.4324 | 10.8317 | 10.4066 | 10.7687 | 9.3183 | 9.4718 | 11.0324 | 9.1855 | 9.7926 | 10.6447 | 9.3744 | 10.4046 | 12.1728 | 9.9717 | 13.4294 | 9.6440 | 9.7552 | 10.3515 | 10.8287 | 11.7389 | 9.7434 | 10.3731 | 10.2816 | 10.2983 | 9.6981 | 10.0209 | 10.9861 | 10.0602 | 9.4816 | 9.6233 | 9.6499 | 9.1077 | 9.8919 | 10.0750 | 10.6152 | 9.4285 | 9.6017 | 10.1242 | 9.7886 | 10.0228 | 9.3084 | 9.8408 | 9.3685 | 9.6971 | 9.7591 | 10.5227 | 9.8998 | 10.8779 | 10.3111 | 10.0779 | 9.9756 | 10.1330 | 9.7030 | 10.4863 | 9.6824 | 9.7079 | 10.6762 | 10.2747 | 9.7562 | 9.7512 | 10.3692 | 10.5168 | 9.9195 | 9.8555 | 9.4452 | 10.7165 | 10.0622 | 9.9254 | 10.3554 | 10.5109 | 10.0258 | 10.3210 | 10.9684 | 9.3311 | 11.2912 | 9.7906 | 11.8540 | 8.8273 | 10.9724 | 9.4915 | 9.4147 | 9.9254 | 10.3849 | 10.1911 | 10.4007 | 11.6149 | 9.7690 | 10.1261 | 10.4440 | 10.8740 | 9.4433 | 10.0720 | 10.4144 | 10.6063 | 10.2049 | 10.6358 | 9.5613 | 10.1409 | 10.1675 | 9.4147 | 8.6807 | 9.7227 | 9.2179 | 10.3308 | 9.3980 | 10.1557 | 9.8044 | 9.1687 | 9.4964 | 9.84935 |
| KRIT1 | 5.5416 | 5.1471 | 5.9670 | 5.6125 | 5.8544 | 6.1310 | 5.9321 | 5.6955 | 6.0890 | 5.8235 | 6.6173 | 6.2715 | 5.7987 | 6.5255 | 5.3326 | 5.5211 | 5.7116 | 6.2849 | 5.6747 | 6.2244 | 6.1885 | 6.0352 | 5.9220 | 6.0823 | 5.9102 | 6.1710 | 6.3676 | 5.9653 | 7.0460 | 5.9327 | 5.4834 | 6.7342 | 5.6363 | 6.0218 | 5.7556 | 5.8027 | 6.5174 | 5.2754 | 6.1249 | 5.5228 | 5.9687 | 5.4458 | 6.7429 | 6.3474 | 6.6519 | 6.1286 | 5.6562 | 5.6975 | 5.8897 | 6.6441 | 5.7062 | 5.7879 | 5.8336 | 6.5033 | 6.3508 | 5.7405 | 5.7687 | 5.8185 | 5.6505 | 6.5097 | 7.2618 | 6.5037 | 5.2922 | 6.3760 | 6.5265 | 5.7597 | 5.2472 | 6.0618 | 5.7597 | 5.5873 | 5.6985 | 5.6834 | 5.5070 | 5.6730 | 5.6256 | 5.4969 | 5.7882 | 5.8312 | 5.7939 | 5.6568 | 5.7613 | 6.7033 | 6.3541 | 5.7351 | 5.6014 | 6.5114 | 5.5853 | 5.6531 | 5.8094 | 5.9257 | 6.1686 | 5.6458 | 5.6105 | 6.0352 | 5.6585 | 5.9892 | 7.5350 | 5.7832 | 5.4616 | 5.8144 | 5.9657 | 5.9952 | 6.0594 | 5.8249 | 5.9166 | 6.9882 | 6.4892 | 5.6199 | 6.6556 | 6.1999 | 5.8887 | 6.5591 | 6.1041 | 6.0665 | 6.7433 | 6.8316 | 5.5819 | 6.0164 | 5.9371 | 6.5941 | 5.9882 | 5.8635 | 5.6999 | 6.6878 | 6.0792 | 5.8034 | 6.0423 | 6.0319 | 5.6266 | 5.5940 | 5.5275 | 5.7708 | 5.9371 | 6.0302 | 5.4105 | 5.8165 | 5.5053 | 5.7190 | 6.1871 | 5.6938 | 5.9011 | 5.5974 | 6.2489 | 6.1303 | 5.6202 | 5.7402 | 6.5013 | 6.4798 | 6.3830 | 5.8030 | 5.7899 | 6.1942 | 5.8907 | 5.5234 | 5.9250 | 5.8269 | 5.7425 | 6.2594 | 6.4838 | 5.9697 | 5.7593 | 5.1256 | 5.5318 | 5.9072 | 6.1787 | 6.0292 | 6.4281 | 5.8430 | 5.7953 | 5.9482 | 5.9364 | 5.7224 | 5.4236 | 5.8249 | 5.7015 | 6.0171 | 6.2254 | 5.6783 | 6.1972 | 6.5198 | 5.4892 | 5.8464 | 5.7375 | 6.0604 | 5.9156 | 6.4439 | 5.6794 | 5.4307 | 5.7587 | 5.9899 | 5.8111 | 5.4700 | 6.2365 | 5.6128 | 5.5668 | 6.0107 | 5.4871 | 5.7251 | 5.2983 | 5.5873 | 6.5957 | 5.6599 | 5.5819 | 5.8249 | 6.1360 | 6.3488 | 5.8786 | 6.0860 | 5.7963 | 5.9435 | 5.9196 | 5.9411 | 5.9169 | 5.6397 | 6.0530 | 5.7546 | 6.0913 | 6.0853 | 5.8000 | 5.6834 | 5.7701 | 6.0201 | 6.2432 | 6.2678 | 5.7667 | 6.7695 | 5.7573 | 6.3145 | 5.9680 | 5.7543 | 5.7422 | 5.8598 | 5.7190 | 6.0221 | 5.8323 | 5.2267 | 5.5298 | 5.7398 | 6.2446 | 5.7563 | 6.0772 | 6.3471 | 5.4122 | 6.1310 | 5.4186 | 6.0040 | 5.6283 | 5.6988 | 5.8316 | 5.8625 | 5.5312 | 5.8064 | 5.5641 | 5.9936 | 6.0275 | 5.7923 | 6.1498 | 5.9825 | 5.9052 | 6.3104 | 5.5036 | 5.6908 | 5.6820 | 5.9976 | 5.2069 | 5.5890 | 6.1337 | 5.8736 | 5.5627 | 6.3898 | 6.2389 | 6.3525 | 5.4982 | 5.7402 | 6.0813 | 6.0403 | 5.7701 | 5.9237 | 5.5107 | 5.9190 | 5.9001 | 6.4879 | 6.0298 | 5.6747 | 5.8870 | 5.5775 | 5.9801 | 5.5056 | 6.0342 | 5.9364 | 5.7113 | 6.4701 | 6.0960 | 5.9193 | 6.6549 | 5.7281 | 5.8642 | 10.6580 | 5.9761 | 5.8339 | 6.4294 | 5.6609 | 5.8299 | 6.0950 | 5.1847 | 6.7863 | 6.0399 | 5.9573 | 6.0598 | 6.5191 | 5.2089 | 5.7442 | 6.0628 | 6.5638 | 6.1817 | 6.0635 | 5.9075 | 5.8608 | 6.6008 | 5.6199 | 5.8568 | 5.4166 | 6.0870 | 6.7954 | 6.5107 | 5.5278 | 5.9633 | 5.7143 | 6.5141 | 6.0272 | 6.5423 | 5.6676 | 5.7503 | 6.3641 | 6.1908 | 6.2326 | 6.2366 | 5.7784 | 6.0722 | 6.3302 | 5.4129 | 5.4208 | 5.6878 | 6.6350 | 6.2734 | 5.1858 | 5.0971 | 6.5723 | 5.5583 | 6.2217 | 4.9557 | 5.7515 | 5.5294 | 6.2645 | 6.0424 | 5.8601 | 5.8262 | 6.1639 | 6.5892 | 5.8322 | 5.3680 | 5.4706 | 5.6569 | 6.0653 | 5.1628 | 6.1709 | 5.7963 | 5.6499 | 5.4497 | 5.8053 | 5.6728 | 6.1619 | 5.6898 | 5.8521 | 6.1081 | 5.6788 | 6.1489 | 5.5135 | 6.0772 | 6.0573 | 5.9667 | 5.4965 | 6.4766 | 6.0633 | 6.3491 | 6.8541 | 5.6808 | 5.3212 | 5.5702 | 7.0075 | 5.9567 | 5.5852 | 6.3322 | 6.3840 | 6.0832 | 6.7884 | 5.4129 | 6.2635 | 6.9089 | 5.8581 | 6.6579 | 5.4915 | 5.9926 | 6.3103 | 6.0812 | 5.5702 | 5.8003 | 5.6678 | 6.0453 | 5.8023 | 5.9657 | 6.2565 | 6.7366 | 6.1370 | 6.2366 | 5.8461 | 6.0404 | 6.7077 | 6.1210 | 5.3780 | 5.6081 | 6.2844 | 5.8342 | 5.8441 | 5.5394 | 6.0175 | 6.0812 | 5.6529 | 5.5762 | 5.9547 | 5.7147 | 5.5423 | 6.5523 | 5.9228 | 6.2734 | 6.2705 | 6.0673 | 5.3382 | 5.8272 | 5.1708 | 5.7157 | 5.9955 | 5.9368 | 6.6260 | 6.1848 | 6.9199 | 6.2685 | 6.1191 | 5.6300 | 5.8999 | 5.7137 | 6.5424 | 6.3611 | 5.8332 | 6.9518 | 6.6669 | 5.5553 | 6.3661 | 6.6221 | 6.2406 | 5.6629 | 6.4229 | 6.0872 | 5.2874 | 6.4677 | 6.9109 | 6.0792 | 5.2136 | 5.6170 | 5.9756 | 5.7924 | 6.0673 | 5.8481 | 6.0244 | 6.1967 | 5.5991 | 5.7296 | 5.7176 | 5.6669 | 6.1918 | 5.9179 | 6.1908 | 5.7426 | 6.5623 | 5.4836 | 6.0155 | 5.7943 | 6.5603 | 6.1738 | 5.7485 | 6.1689 | 6.6181 | 6.8512 | 6.6788 | 5.9736 | 5.9338 | 5.7744 | 5.8242 | 6.5563 | 5.9258 | 6.0822 | 5.7684 | 5.8671 | 5.9447 | 6.1629 | 6.5822 | 6.8492 | 5.6688 | 6.4836 | 5.6220 | 6.2416 | 6.0384 | 5.9836 | 5.5971 | 6.3910 | 5.4686 | 5.5633 | NA | 5.9647 | 5.9129 | 6.3452 | 5.7635 | 6.0623 | 5.9208 | 5.9089 | 5.6081 | 6.1171 | 6.2665 | 5.3641 | 6.3890 | 5.4238 | 5.7306 | 5.7077 | 6.4587 | 5.3302 | 6.3671 | 5.3123 | 6.4995 | 7.0334 | 6.0165 | 5.8511 | 6.0772 | 5.8671 | 6.7426 | 5.5662 | 6.2256 | 6.0015 | 6.1021 | 6.0792 | 6.1778 | 5.9836 | 5.7167 | 5.4726 | 6.6778 | 6.8631 | 5.7784 | 6.3422 | 6.3362 | 6.1330 | 5.3322 | 5.8461 | 5.7196 | 5.2336 | 4.7614 | 6.2037 | 5.9248 | 6.0214 | 6.3970 | 6.0892 | 6.5045 | 5.9776 | 5.8720 | 6.2625 | 6.0633 | 6.0304 | 5.9208 | 5.9687 | 6.2197 | 5.9736 | 5.6868 | 6.0603 | 6.4717 | 5.7505 | 5.8332 | 5.7147 | 6.1031 | 6.2087 | 5.7545 | 5.5583 | 6.0444 | 5.6519 | 6.2207 | 6.5802 | 6.2595 | 6.6460 | 5.9258 | 5.9408 | 5.5971 | 6.7874 | 6.0971 | 6.1390 | 6.5653 | 5.6708 | 6.3681 | 6.2545 | 5.7714 | 6.5972 | 6.2436 | 5.8033 | 6.0673 | 5.9826 | 6.1320 | 5.6270 | 5.9627 | 6.4577 | 6.1579 | 6.0991 | 6.3930 | 6.6739 | 6.2724 | 5.8023 | 5.8332 | 7.0424 | 5.9358 | 6.3671 | 5.9428 | 6.0882 | 6.0175 | 5.2027 | 5.6200 | 6.2097 | 6.2854 | 5.8521 | 6.5195 | 5.8242 | 6.5932 | 6.3213 | 6.1878 | 6.1360 | 6.6470 | 5.2385 | 6.6609 | 6.4986 | 5.6061 | 5.7077 | 5.5862 | 6.4577 | 5.7465 | 6.3173 | 6.7296 | 4.7804 | 5.3133 | 6.0673 | 6.3362 | 5.9378 | 6.7087 | 5.4398 | 6.8263 | 5.2246 | 6.2426 | 6.1041 | 6.4019 | 5.8103 | 7.6490 | 5.5862 | 5.9816 | 5.7107 | 6.4906 | 5.1668 | 6.5314 | 6.7525 | 5.2854 | 6.1440 | 6.1629 | 6.0015 | 5.4726 | 5.7535 | 6.2824 | 5.5692 | 6.4099 | 6.7217 | 5.9338 | 6.0214 | 6.6470 | 6.2157 | 5.8103 | 6.0115 | 5.6260 | 6.0075 | 6.1758 | 5.8023 | 5.7206 | 6.1679 | 5.7196 | 6.7406 | 6.8651 | 6.4438 | 6.2306 | 6.0613 | 5.5971 | 6.3232 | 6.3611 | 6.4418 | 6.3472 | 6.8213 | 6.2715 | 4.8511 | 5.8661 | 6.0782 | 5.6748 | 5.0423 | 6.4129 | 6.1390 | 7.2257 | 5.7077 | 6.4995 | 6.7725 | 6.6021 | 5.7296 | 5.8043 | 5.7874 | 7.1729 | 5.8013 | 6.4458 | 5.7874 | 6.6021 | 5.9856 | 5.6280 | 6.2047 | 5.0403 | 6.0324 | 6.0195 | 5.5125 | 5.6848 | 5.2555 | 6.5414 | 6.3860 | 5.7714 | 5.7615 | 5.2186 | 6.3581 | 5.9567 | 8.7516 | 6.3392 | 6.0244 | 6.1798 | 5.5005 | 5.9796 | 6.4776 | 6.2446 | 5.8153 | 5.7286 | 6.0314 | 5.8661 | 5.8730 | 5.5005 | 5.6977 | 6.1669 | 5.6788 | 5.7455 | 5.5274 | 4.8909 | 5.8591 | 5.7655 | 5.8760 | 5.2814 | 5.4706 | 5.7206 | 4.9427 | 5.8850 | 5.4348 | 6.0135 | 5.6310 | 5.3631 | 6.1599 | 5.4547 | 5.2465 | 5.5742 | 5.0473 | 5.9069 | 5.7714 | 6.2087 | 5.6071 | 6.3641 | 5.2814 | 6.0095 | 5.1748 | 5.9975 | 5.8392 | 5.3053 | 5.9876 | 5.2973 | 5.8750 | 5.6240 | 5.2764 | 5.3880 | 5.6708 | 6.0553 | 6.0792 | 5.6908 | 5.2714 | 5.5672 | 5.3033 | 6.2485 | 5.7495 | 6.3223 | 5.5742 | 5.7117 | 6.1609 | 5.7067 | 5.9477 | 5.6967 | 5.2117 | 5.6858 | 5.7366 | 5.6310 | 5.8830 | 5.4846 | 5.8939 | 5.6579 | 6.2475 | 5.7346 | 5.3989 | 5.7485 | 5.7376 | 5.7545 | 5.5902 | 5.5593 | 5.5563 | 5.7943 | 5.8242 | 5.5772 | 5.8710 | 5.4527 | 5.9438 | 5.5892 | 5.8242 | 5.6340 | 5.7286 | 5.5404 | 6.3661 | 5.7107 | 5.5244 | 5.6081 | 5.5503 | 6.1748 | 5.5214 | 5.0553 | 5.0204 | 5.1310 | 5.5503 | 5.0115 | 5.6967 | 6.5145 | 5.4188 | 5.9069 | 5.7276 | 5.9906 | 5.8322 | 6.2296 | 5.7774 | 5.3770 | 5.7665 | 6.1539 | 5.0931 | 6.2525 | 5.9218 | 5.7465 | 6.0703 | 5.7525 | 5.8750 | 5.5892 | 5.8920 | 5.5543 | 6.1848 | 5.6439 | 5.2973 | 6.1649 | 5.6340 | 6.3192 | 6.2406 | 6.4029 | 6.3262 | 4.9865 | 5.9607 | 5.4268 | 5.5523 | 6.0204 | 6.4089 | 6.1400 | 6.4438 | 5.5164 | 5.4228 | 5.3770 | 7.9518 | 5.6609 | 5.2475 | 5.6399 | 5.7236 | 5.6021 | 5.5842 | 5.7395 | 5.3939 | 6.3033 | 5.3700 | 5.9139 | 5.9119 | 5.8471 | 5.3571 | 6.1260 | 5.2216 | 6.3900 | 4.8859 | 5.9866 | 6.1091 | 5.1887 | 5.8870 | 5.7196 | 5.6509 | 6.4647 | 5.2893 | 6.3103 | 6.2844 | 5.6449 | 5.3322 | 5.9457 | 6.0005 | 5.0961 | 5.2814 | 6.4657 | 6.0274 | 5.6160 | 5.6887 | 5.9139 | 5.7704 | 5.1300 | 5.2186 | 5.3063 | 6.1131 | 6.0513 | 5.3112 | 5.5523 | 5.8382 | 6.1519 | 6.1848 | 5.0294 | 5.3531 | 5.5812 | 5.0045 | 6.0593 | 5.8292 | 4.8939 | 5.8202 | 6.1439 | 5.3322 | 6.1360 | 5.4089 | 6.1569 | 5.3451 | 6.4169 | 6.4139 | 5.9756 | 5.6121 | 5.8880 | 5.3800 | 6.0722 | 6.2346 | 5.4517 | 6.1420 | 6.3710 | 5.4935 | 5.6479 | 5.9328 | 5.3312 | 5.4666 | 6.4258 | 6.2246 | 5.1170 | 5.4477 | 6.6798 | 5.1857 | 6.1370 | 5.1937 | 5.9656 | 6.5254 | 5.2913 | 6.33150 |
| RAD52 | 6.1560 | 5.7671 | 6.7864 | 6.4826 | 6.9222 | 6.8361 | 6.6163 | 6.2856 | 6.8538 | 6.9263 | 7.6998 | 7.1783 | 6.9699 | 7.5485 | 6.3882 | 6.2980 | 6.5977 | 7.5599 | 6.6122 | 7.0964 | 6.8382 | 6.5904 | 7.1503 | 7.0010 | 6.0761 | 7.7662 | 6.7677 | 6.5676 | 8.0762 | 7.4831 | 6.7926 | 7.5132 | 7.2602 | 7.8782 | 6.6982 | 6.4349 | 7.3577 | 6.5230 | 6.8880 | 6.8361 | 7.0300 | 6.4846 | 7.8408 | 7.5982 | 7.6770 | 7.1700 | 6.3509 | 7.1223 | 6.8081 | 7.0072 | 7.0943 | 6.7128 | 6.8019 | 7.4572 | 6.8569 | 6.7428 | 6.5583 | 6.5562 | 6.1663 | 8.1685 | 8.0793 | 7.7859 | 6.2171 | 7.2187 | 7.2955 | 6.6039 | 5.9621 | 7.0062 | 6.8890 | 6.5925 | 6.4805 | 6.6018 | 6.7687 | 6.2856 | 6.8755 | 7.1399 | 6.7034 | 7.7465 | 6.3105 | 6.7013 | 6.2285 | 7.3359 | 7.4748 | 6.5811 | 6.2348 | 7.3214 | 6.4774 | 7.5972 | 7.9767 | 6.9730 | 7.9435 | 6.4525 | 5.8325 | 7.7880 | 7.3390 | 7.0477 | 6.9429 | 6.7304 | 6.9699 | 6.7086 | 7.0238 | 6.7480 | 7.2084 | 6.8859 | 7.0871 | 8.3199 | 7.1783 | 7.1482 | 7.7475 | 6.8901 | 6.3934 | 7.4821 | 7.5464 | 6.7065 | 7.6324 | 7.2675 | 6.4712 | 7.2167 | 7.3307 | 6.9315 | 6.5189 | 6.3540 | 6.7511 | 7.5267 | 6.4266 | 7.2861 | 6.8216 | 7.0020 | 6.7314 | 6.7128 | 6.3913 | 6.9108 | 6.9295 | 6.7335 | 6.3913 | 6.7998 | 6.3426 | 7.3328 | 6.8704 | 7.1327 | 6.8631 | 6.3789 | 7.1783 | 6.5914 | 6.4681 | 6.7770 | 7.6003 | 7.3100 | 6.8227 | 6.3167 | 6.8216 | 7.4562 | 6.7148 | 6.9222 | 6.9035 | 6.5842 | 7.7465 | 7.2011 | 7.8077 | 7.1182 | 6.9595 | 6.3882 | 6.5977 | 6.5448 | 7.1793 | 6.2472 | 7.1441 | 6.5666 | 6.1902 | 7.2322 | 6.1497 | 6.7947 | 6.4183 | 8.0907 | 6.4266 | 6.4608 | 7.4396 | 6.4090 | 7.5360 | 7.3919 | 6.5220 | 7.0466 | 6.6215 | 6.9035 | 6.6671 | 7.5547 | 6.9606 | 6.0720 | 6.7314 | 6.8299 | 7.0207 | 6.2399 | 7.1337 | 6.4266 | 8.0586 | 6.6868 | 6.7397 | 6.7407 | 6.5510 | 7.0342 | 7.5547 | 6.4587 | 6.6734 | 6.2005 | 6.9699 | 6.9481 | 6.7667 | 7.1057 | 6.3250 | 7.0176 | 6.7936 | 6.8942 | 7.5858 | 6.9253 | 7.3473 | 6.9129 | 7.5080 | 6.6308 | 6.8351 | 7.0757 | 6.9523 | 7.0995 | 8.0855 | 7.4759 | 7.0435 | 7.5754 | 7.2571 | 7.1099 | 7.2602 | 6.2721 | 7.9829 | 6.7957 | 7.0031 | 7.0331 | 6.6277 | 6.9989 | 6.5437 | 6.7480 | 7.1773 | 6.5106 | 7.0788 | 7.3566 | 6.6049 | 7.4489 | 6.5852 | 6.6547 | 7.0767 | 7.0456 | 6.2607 | 6.3540 | 6.9917 | 6.1508 | 6.7604 | 7.6760 | 6.6537 | 6.8009 | 6.7905 | 6.8755 | 6.9844 | 7.8087 | 6.4079 | 7.1327 | 6.7013 | 6.8786 | 6.4753 | 6.7107 | 7.4437 | 7.0497 | 5.9828 | 7.4925 | 7.1016 | 7.2301 | 6.0264 | 6.4494 | 6.8755 | 6.6951 | 6.8766 | 7.3224 | 8.5666 | 7.2322 | 7.1638 | 7.3722 | 7.2405 | 6.5697 | 6.7781 | 6.7045 | 6.8278 | 6.4805 | 6.6993 | 7.0622 | 7.2436 | 7.5059 | 6.7242 | 6.7231 | 7.1513 | 6.2970 | 7.1503 | 8.9347 | 7.1202 | 7.2467 | 7.7330 | 6.5956 | 6.2213 | 7.7620 | 6.3436 | 7.6770 | 6.9429 | 6.9823 | 6.5189 | 7.5267 | 6.1570 | 6.7407 | 7.4862 | 7.4375 | 7.3929 | 7.7735 | 7.0435 | 7.1244 | 7.3203 | 6.9098 | 7.0300 | 6.3011 | 6.8258 | 7.8201 | 7.5225 | 6.4214 | 6.7076 | 6.5023 | 7.1959 | 6.8475 | 7.4945 | 6.5769 | 6.5676 | 7.3110 | 6.9785 | 7.1619 | 7.0148 | 7.0295 | 6.2272 | 6.7343 | 6.5724 | 6.0232 | 6.3174 | 7.4885 | 7.0913 | 7.2364 | 6.2831 | 6.8804 | 6.7519 | 7.0118 | 7.0373 | 6.5734 | 6.5116 | 6.8284 | 6.7529 | 5.8741 | 6.9902 | 6.6872 | 7.0187 | 6.5960 | 6.3439 | 6.4822 | 7.1334 | 6.8686 | 6.7431 | 6.8784 | 6.5675 | 6.5371 | 6.5842 | 7.0118 | 6.1987 | 6.8529 | 7.5522 | 6.3439 | 7.4012 | 7.1138 | 7.0873 | 7.3090 | 6.7686 | 8.7812 | 6.9804 | 6.7921 | 8.2025 | 7.1746 | 7.7719 | 6.9206 | 7.1903 | 6.6833 | 7.0157 | 7.7258 | 6.4184 | 6.6597 | 7.3708 | 6.4361 | 7.0687 | 7.0256 | 6.9373 | 7.1884 | 7.0108 | 6.9618 | 6.5597 | 6.2095 | 6.9285 | 6.9451 | 7.6464 | 6.4479 | 7.5503 | 7.6739 | 6.3910 | 7.6611 | 6.5479 | 7.6042 | 7.2570 | 6.4008 | 6.4851 | 6.8333 | 6.9589 | 7.5483 | 6.8353 | 6.8039 | 6.4577 | 6.8892 | 6.4508 | 7.3188 | 6.3625 | 7.3953 | 7.2502 | 7.0913 | 7.0844 | 6.3920 | 6.1379 | 6.5842 | 7.0157 | 6.5979 | 7.0383 | 7.0864 | 6.9010 | 6.8274 | 7.1334 | 6.3115 | 7.2963 | 7.6984 | 6.9559 | 7.4110 | 7.0040 | 7.1079 | 6.5763 | 6.7843 | 6.1781 | 6.6999 | 6.9088 | 7.0785 | 8.0809 | 6.9363 | 7.6542 | 7.7631 | 6.1585 | 7.1246 | 7.4542 | 7.0932 | 6.8559 | 7.4071 | 6.4743 | 6.7470 | 6.5842 | 7.1383 | 6.8421 | 7.0226 | 6.8166 | 6.8863 | 6.5361 | 6.6891 | 6.3488 | 6.8882 | 7.1521 | 6.3478 | 6.4802 | 7.5993 | 6.3684 | 6.8117 | 6.4763 | 7.3208 | 7.5483 | 7.3992 | 6.4361 | 6.8902 | 7.1452 | 7.9367 | 7.0099 | 7.1050 | 6.9687 | 7.3374 | 7.0010 | 7.0511 | 6.4832 | 6.8873 | 6.2998 | 6.6940 | 7.3796 | 6.7990 | 6.7264 | 6.6175 | 7.3835 | 7.4571 | 7.3590 | 7.0677 | 7.5611 | 6.6323 | 7.4708 | 6.4057 | 6.8392 | 6.7617 | 7.1619 | 6.7813 | 7.1030 | 6.0820 | 5.6564 | 7.1531 | 7.1070 | 6.6607 | 7.1001 | 6.6411 | 6.4067 | 6.9128 | 6.5302 | 6.9491 | 6.7490 | 7.1256 | 6.9510 | 7.0628 | 6.9137 | 7.1109 | 6.7333 | 6.2752 | 6.5450 | 8.2349 | 7.0020 | 7.4787 | 7.5983 | 7.5728 | 7.0638 | 6.6940 | 8.1917 | 6.8824 | 6.8255 | 7.2796 | 6.7333 | 6.8402 | 6.8902 | 6.0595 | 7.7965 | 6.4214 | 6.5969 | 6.8078 | 7.2119 | 7.3414 | 6.7078 | 7.0432 | 7.4473 | 6.4037 | 7.1187 | 6.4802 | 6.0869 | 7.1236 | 6.9441 | 6.4881 | 6.9412 | 6.9363 | 7.0932 | 6.8873 | 6.8265 | 7.1795 | 7.7818 | 6.6421 | 8.5095 | 6.4969 | 6.9549 | 6.9853 | 6.5744 | 6.8225 | 6.3714 | 7.2109 | 6.4969 | 6.2605 | 6.3086 | 7.3070 | 6.9824 | 6.3478 | 6.8215 | 6.7303 | 6.6234 | 7.4493 | 6.8343 | 6.5253 | 7.6592 | 6.5332 | 7.1030 | 8.6556 | 7.2031 | 6.4959 | 7.0403 | 7.7406 | 6.9353 | 6.9235 | 6.8843 | 7.3345 | 6.9687 | 6.9844 | 6.1948 | 6.9951 | 6.9549 | 6.9304 | 6.2576 | 7.1786 | 6.8873 | 6.8323 | 6.4959 | 7.1658 | 6.9647 | 7.2168 | 6.6166 | 6.4783 | 7.3021 | 6.8274 | 6.8794 | 6.3772 | 6.9422 | 5.9987 | 7.1638 | 6.8559 | 6.7980 | 7.1825 | 6.7019 | 7.6356 | 7.4993 | 7.1560 | 7.2913 | 6.8765 | 7.6601 | 7.0295 | 6.5302 | 7.2080 | 7.8602 | 6.8637 | 6.4282 | 6.5695 | 7.3443 | 6.9343 | 7.0324 | 7.7523 | 6.3871 | 6.8716 | 6.6038 | 6.7303 | 6.9716 | 7.9161 | 6.4273 | 7.9995 | 7.0560 | 6.6421 | 7.1599 | 7.1658 | 6.6999 | 9.3716 | 6.3400 | 7.3365 | 6.7117 | 6.9334 | 6.2429 | 6.6097 | 8.3271 | 6.5047 | 7.0177 | 7.1491 | 6.7647 | 7.2158 | 6.6803 | 6.7029 | 6.5459 | 6.9696 | 7.3247 | 6.8863 | 7.5110 | 7.2335 | 7.0157 | 6.9961 | 6.6352 | 6.8775 | 7.2619 | 6.8019 | 6.9461 | 6.0614 | 6.8421 | 6.2399 | 6.7411 | 7.2943 | 7.3414 | 6.9275 | 6.9746 | 6.1958 | 6.4165 | 6.9824 | 7.1364 | 7.7631 | 6.9157 | 6.7137 | 7.0913 | 6.7401 | 7.0972 | 6.4557 | 6.4273 | 7.1138 | 6.2546 | 7.2609 | 6.8402 | 7.4228 | 7.4600 | 6.8647 | 6.2458 | 6.4704 | 6.9294 | 7.0824 | 6.4175 | 6.8196 | 6.6950 | 6.6734 | 8.5252 | 6.3017 | 7.6562 | 7.1903 | 8.6115 | 6.9118 | 6.4508 | 6.9363 | 6.7686 | 7.5983 | 9.0744 | 6.5401 | 6.5636 | 6.6617 | 7.0324 | 7.0030 | 7.5954 | 7.0040 | 7.5591 | 7.2580 | 6.8304 | 7.5356 | 7.0697 | 6.9736 | 6.8775 | 6.0379 | 6.8157 | 7.3247 | 6.6636 | 6.9216 | 6.5656 | 6.6607 | 7.2168 | 6.6273 | 7.1423 | 6.5803 | 6.9098 | 7.0030 | 6.6803 | 6.9049 | 6.5361 | 6.6332 | 6.5940 | 6.7666 | 6.5724 | 7.9093 | 7.0246 | 6.1134 | 6.6783 | 7.0775 | 7.4375 | 6.3311 | 7.4336 | 6.8569 | 7.7023 | 7.9524 | 6.6774 | 6.8873 | 7.0236 | 6.5420 | 6.1487 | 6.6891 | 6.6381 | 7.1864 | 6.7156 | 6.7813 | 8.8950 | 6.6558 | 6.2409 | 7.8484 | 6.9942 | 7.2658 | 6.9373 | 7.0991 | 7.0393 | 6.9402 | 7.1599 | 6.6146 | 7.5248 | 6.9353 | 7.2198 | 7.0079 | 7.5601 | 6.9010 | 6.5862 | 7.1854 | 7.7190 | 6.6813 | 7.4365 | 6.8725 | 6.5371 | 6.7882 | 6.2301 | 7.0069 | 7.1825 | 6.9383 | 6.8421 | 7.8906 | 6.9461 | 7.2766 | 6.5714 | 6.7617 | 6.7990 | 6.9128 | 7.5640 | 6.8382 | 7.5248 | 6.1507 | 6.7568 | 6.9608 | 6.5597 | 6.9373 | 7.2482 | 7.2923 | 7.4502 | 6.7705 | 6.6960 | 6.5126 | 6.7558 | 6.9863 | 6.9118 | 6.8569 | 9.7541 | 7.1158 | 7.0981 | 6.5077 | 6.9598 | 7.1746 | 6.9285 | 7.2551 | 6.4018 | 7.1334 | 6.7892 | 7.0373 | 6.7902 | 6.0045 | 6.5381 | 6.3527 | 6.5960 | 7.2296 | 6.9098 | 8.8253 | 6.9108 | 6.3145 | 7.0148 | 6.6411 | 7.2060 | 6.7617 | 7.1168 | 6.4106 | 6.3517 | 7.0913 | 6.4724 | 7.4463 | 6.0565 | 7.5277 | 7.9171 | 6.4498 | 5.8123 | 5.8731 | 6.6892 | 7.7916 | 6.8490 | 6.2988 | 7.2070 | 6.3910 | 6.2262 | 6.2174 | 7.7857 | 7.0069 | 5.8594 | 6.5293 | 6.7176 | 5.3602 | 6.0467 | 6.4606 | 6.4783 | 7.3002 | 5.9585 | 6.3557 | 7.2904 | 6.5548 | 6.3292 | 7.4169 | 6.4371 | 7.2747 | 6.1370 | 7.2247 | 6.6342 | 6.1782 | 6.5057 | 7.1580 | 6.2998 | 8.5831 | 6.3773 | 6.8745 | 6.6744 | 6.1281 | 6.4685 | 6.9059 | 6.1203 | 6.3939 | 6.1948 | 7.2168 | 6.9422 | 6.0251 | 5.8457 | 6.7990 | 6.2174 | 7.1364 | 5.8368 | 6.5410 | 6.6872 | 6.0320 | 6.7392 | 6.7451 | 6.3763 | 7.6611 | 6.8274 | 6.3665 | 6.3674 | 6.3586 | 5.8996 | 6.6872 | 6.5675 | 5.7849 | 6.4420 | 6.4341 | 7.0118 | 6.3488 | 6.1262 | 6.3331 | 5.8104 | 6.4793 | 6.6038 | 6.2507 | 6.1703 | 6.1379 | 7.0589 | 6.0869 | 6.8245 | 6.9255 | 6.7980 | 6.5116 | 6.2811 | 6.1183 | 6.1958 | 5.9075 | 5.7927 | 6.9736 | 6.3174 | 5.8535 | 6.7460 | 7.0628 | 6.0811 | 6.3439 | 6.1448 | 6.3792 | 6.4851 | 6.5587 | 6.95470 |
Annotation Data
Displays gene annotation for the dataset.
# Display the first 20 rows
kable(head(annot, 20), caption = "Gene Annotation Data") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| source | type | score | phase | gene_id | gene_type | gene_name | level | havana_gene | tag | gene_id_no_ver | length | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TSPAN6 | HAVANA | gene | NA | NA | ENSG00000000003.10 | protein_coding | TSPAN6 | 2 | OTTHUMG00000022002.1 | NA | ENSG00000000003 | NA |
| TNMD | HAVANA | gene | NA | NA | ENSG00000000005.5 | protein_coding | TNMD | 2 | OTTHUMG00000022001.1 | NA | ENSG00000000005 | NA |
| DPM1 | HAVANA | gene | NA | NA | ENSG00000000419.8 | protein_coding | DPM1 | 2 | OTTHUMG00000032742.2 | NA | ENSG00000000419 | NA |
| SCYL3 | HAVANA | gene | NA | NA | ENSG00000000457.9 | protein_coding | SCYL3 | 2 | OTTHUMG00000035941.4 | NA | ENSG00000000457 | NA |
| C1orf112 | HAVANA | gene | NA | NA | ENSG00000000460.12 | protein_coding | C1orf112 | 2 | OTTHUMG00000035821.6 | NA | ENSG00000000460 | NA |
| FGR | HAVANA | gene | NA | NA | ENSG00000000938.8 | protein_coding | FGR | 2 | OTTHUMG00000003516.1 | NA | ENSG00000000938 | NA |
| CFH | HAVANA | gene | NA | NA | ENSG00000000971.11 | protein_coding | CFH | 1 | OTTHUMG00000035607.4 | NA | ENSG00000000971 | NA |
| FUCA2 | HAVANA | gene | NA | NA | ENSG00000001036.9 | protein_coding | FUCA2 | 2 | OTTHUMG00000015728.2 | NA | ENSG00000001036 | NA |
| GCLC | HAVANA | gene | NA | NA | ENSG00000001084.6 | protein_coding | GCLC | 2 | OTTHUMG00000160220.4 | NA | ENSG00000001084 | NA |
| NFYA | HAVANA | gene | NA | NA | ENSG00000001167.10 | protein_coding | NFYA | 2 | OTTHUMG00000014669.1 | NA | ENSG00000001167 | NA |
| STPG1 | HAVANA | gene | NA | NA | ENSG00000001460.13 | protein_coding | STPG1 | 2 | OTTHUMG00000003297.2 | NA | ENSG00000001460 | NA |
| NIPAL3 | HAVANA | gene | NA | NA | ENSG00000001461.12 | protein_coding | NIPAL3 | 2 | OTTHUMG00000003299.3 | NA | ENSG00000001461 | NA |
| LAS1L | HAVANA | gene | NA | NA | ENSG00000001497.12 | protein_coding | LAS1L | 2 | OTTHUMG00000021720.2 | NA | ENSG00000001497 | NA |
| ENPP4 | HAVANA | gene | NA | NA | ENSG00000001561.6 | protein_coding | ENPP4 | 2 | OTTHUMG00000014779.2 | NA | ENSG00000001561 | NA |
| SEMA3F | HAVANA | gene | NA | NA | ENSG00000001617.7 | protein_coding | SEMA3F | 2 | OTTHUMG00000156806.7 | ncRNA_host | ENSG00000001617 | NA |
| CFTR | HAVANA | gene | NA | NA | ENSG00000001626.10 | protein_coding | CFTR | 1 | OTTHUMG00000023076.10 | NA | ENSG00000001626 | NA |
| ANKIB1 | HAVANA | gene | NA | NA | ENSG00000001629.5 | protein_coding | ANKIB1 | 2 | OTTHUMG00000155859.1 | NA | ENSG00000001629 | NA |
| CYP51A1 | HAVANA | gene | NA | NA | ENSG00000001630.11 | protein_coding | CYP51A1 | 1 | OTTHUMG00000131131.5 | NA | ENSG00000001630 | NA |
| KRIT1 | HAVANA | gene | NA | NA | ENSG00000001631.10 | protein_coding | KRIT1 | 2 | OTTHUMG00000131187.7 | ncRNA_host | ENSG00000001631 | NA |
| RAD52 | HAVANA | gene | NA | NA | ENSG00000002016.12 | protein_coding | RAD52 | 2 | OTTHUMG00000090361.4 | NA | ENSG00000002016 | NA |
Load Radiomics Data
The radiomics dataset includes dynamic contrast-enhanced MRI (DCE-MRI) scans used to monitor tumor response to treatment.
Metadata Source:
File:
ISPY2-Imaging-Cohort-1-Clinical-Data.xlsxTotal Patients: 985
- 719 I-SPY2 cases
- 266 ACRIN-6698 cases
Radiomics (MRI) Data:
Each patient has 4 MRI scans (T1–T4)
MRI features include:
- Functional Tumor Volume (FTV)
- Longest Tumor Diameter
- Sphericity
Data collected from 22+ clinical centers
# Load radiomics clinical data
Radiomics_clin <- read_excel(file.path(input_dir, "ISPY2-Imaging-Cohort-1-Clinical-Data.xlsx"))
# Display radiomics metadata with scrolling
kable(Radiomics_clin, caption = "Radiomics Clinical Data") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| Patient_ID | Arm | HR | HER2 | MP | pCR | Age_at_Screening | Race | menopausal_status | ethnicity |
|---|---|---|---|---|---|---|---|---|---|
| 100899 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 102011 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 1 | 32 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 102212 | Paclitaxel + MK-2206 | 0 | 0 | 0 | 0 | 26 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 103693 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 103939 | Paclitaxel | 1 | 0 | 0 | 0 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 104268 | Paclitaxel | 0 | 0 | 1 | 0 | 50 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 104384 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 42 | American Indian or Alaska Native | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 105286 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 65 | White | NA | Not Hispanic or Latino |
| 105513 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 107700 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 68 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 108939 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 34 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 108969 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 109623 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 109874 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 43 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 109980 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 111004 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | NA | NA | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111038 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 28 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111344 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 111646 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 66 | White | NA | Not Hispanic or Latino |
| 111674 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 1 | 30 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111881 | Paclitaxel + Neratinib | 1 | 1 | 1 | 1 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 112606 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 114087 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 115638 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 115987 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 116165 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 116603 | Paclitaxel | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 117424 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 117707 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 50 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 118307 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 44 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 119928 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 120001 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 53 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 120422 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 122287 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 122579 | Paclitaxel | 1 | 0 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 122795 | Paclitaxel + Ganitumab | 0 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 123660 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 71 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 125130 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 125418 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 49 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 127675 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 127791 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 128051 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 128675 | Paclitaxel | 1 | 0 | 1 | 1 | 47 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 129837 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 67 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 129973 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 35 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 130580 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 130892 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 1 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 131595 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 131961 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 44 | White | NA | Not Hispanic or Latino |
| 132463 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 1 | 1 | 64 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 133650 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 134526 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 136536 | Paclitaxel | 0 | 0 | 1 | 1 | 42 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 138027 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 64 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 138425 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 62 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 139137 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 139771 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 139973 | Paclitaxel | 1 | 0 | 0 | 0 | 41 | White | NA | Not Hispanic or Latino |
| 141782 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 54 | White | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 142688 | Paclitaxel | 0 | 0 | 1 | 0 | 45 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 144302 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 145513 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 32 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 145777 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 30 | Asian | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 146033 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 53 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 146987 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 53 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 147139 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 52 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 148357 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 55 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 149654 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | NA | NA | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 150547 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 151230 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 45 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 151481 | Paclitaxel | 0 | 0 | 0 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 151980 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 1 | 46 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 152090 | Paclitaxel | 1 | 0 | 1 | 1 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 152197 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 153327 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 153880 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 154293 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 52 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 155171 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 156163 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 157270 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 157463 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 159284 | Paclitaxel | 0 | 0 | 0 | 0 | 35 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 159352 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 160120 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 55 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 162562 | Paclitaxel + Trastuzumab | 0 | 1 | 1 | 1 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 164468 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 165925 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 50 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 166412 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 166782 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 52 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 167271 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 33 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 168044 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 169536 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 25 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 169918 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 172168 | Paclitaxel | 0 | 0 | 1 | 0 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 172283 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 48 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 172366 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 174903 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 174904 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 177795 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 178649 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 178815 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 179369 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 179568 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 180027 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 40 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 180663 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 181442 | Paclitaxel | 0 | 0 | 1 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 181819 | Paclitaxel | 1 | 0 | 0 | 1 | 32 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 182346 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 183831 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 1 | 49 | Asian | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 188091 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 50 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 188511 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 188700 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 190224 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 192548 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 0 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 194024 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 196024 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 67 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 196064 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 50 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 197942 | Paclitaxel | 0 | 0 | 0 | 0 | 34 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 198891 | Paclitaxel | 1 | 0 | 0 | 0 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 199115 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 199960 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 200222 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 70 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 201831 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 44 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 201873 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 49 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 202535 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 202539 | Paclitaxel | 1 | 0 | 0 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 202956 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 49 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 203060 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 203254 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 25 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 204939 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 49 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 208265 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 208303 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 64 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 208650 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 39 | White | NA | Not Hispanic or Latino |
| 209397 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 209967 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 211408 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 212307 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 213328 | Paclitaxel | 0 | 0 | 1 | 1 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 213672 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 213913 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 69 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 215932 | Paclitaxel + AMG 386 + Trastuzumab | 0 | 1 | 1 | 0 | 43 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 218249 | Paclitaxel | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 218503 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 219545 | Paclitaxel | 0 | 0 | 1 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 220471 | Paclitaxel + Trastuzumab | 0 | 1 | 1 | 0 | 50 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 220664 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 47 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 220925 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 221375 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 221686 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 47 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 222135 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 53 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 223030 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 223526 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 225836 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 70 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 227055 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 1 | 0 | 40 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 227832 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 53 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 227881 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 49 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 228192 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 56 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 228340 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 229144 | Paclitaxel | 1 | 0 | 0 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 229328 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 229824 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 231633 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 233191 | Paclitaxel | 0 | 0 | 1 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 233832 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 42 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 233962 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 234272 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 41 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 234723 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 235995 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 50 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 236470 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 54 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 237158 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 238790 | Paclitaxel | 0 | 0 | 1 | 0 | 44 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 239061 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 70 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 239910 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 240035 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 240432 | Paclitaxel | 1 | 0 | 0 | 0 | 48 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 240957 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 241705 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 49 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 241998 | Paclitaxel | 1 | 0 | 0 | 0 | 54 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 242370 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 243836 | Paclitaxel + Neratinib | 1 | 0 | 1 | 1 | 31 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 245655 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 43 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 246134 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 68 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 247641 | Paclitaxel | 0 | 0 | 1 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 248255 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 31 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 250274 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 43 | Asian | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 252748 | Paclitaxel | 0 | 0 | 1 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 253531 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 59 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 254060 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 254273 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 255078 | Paclitaxel | 0 | 0 | 1 | 0 | 57 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 255388 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 255535 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 44 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 255577 | Paclitaxel | 0 | 0 | 1 | 0 | 50 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 257735 | Paclitaxel | 0 | 0 | 1 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 259206 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 64 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 259899 | Paclitaxel | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 261304 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 262131 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 263143 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 0 | 54 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 264305 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 264678 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 266509 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 266840 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 267306 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 268937 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 50 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 269899 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 1 | 58 | White | NA | Not Hispanic or Latino |
| 273691 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 46 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 273745 | Paclitaxel | 1 | 0 | 0 | 0 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 275034 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 1 | 1 | 27 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 275626 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 42 | Native Hawaiian or Pacific Islander;White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 277848 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 277888 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 1 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 279902 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 1 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 280375 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 282082 | Paclitaxel | 0 | 0 | 1 | 1 | NA | NULL | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 282644 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 62 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 282777 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 283070 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 284355 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 284443 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 284593 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 32 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 285339 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 286984 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 287300 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 287961 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 1 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 289107 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 50 | American Indian or Alaska Native | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 289420 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 64 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 290413 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 291515 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 293142 | Paclitaxel | 1 | 0 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 294176 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 294265 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 52 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 294739 | Paclitaxel | 1 | 0 | 1 | 0 | 42 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 296123 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 62 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 296841 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 298101 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 71 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 299364 | Paclitaxel | 0 | 0 | 1 | 0 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 299840 | Paclitaxel | 0 | 0 | 1 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 299962 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 300724 | Paclitaxel | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 301289 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 301665 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 52 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 301968 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 45 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 303685 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 71 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 303947 | Paclitaxel + Neratinib | 0 | 1 | 1 | 1 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 306127 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 55 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 306401 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 58 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 307659 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 309830 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 311316 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 311455 | Paclitaxel | 1 | 0 | 0 | 0 | 58 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 313243 | Paclitaxel | 1 | 0 | 1 | 1 | 36 | White | NA | Not Hispanic or Latino |
| 313672 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 73 | White | NA | Not Hispanic or Latino |
| 316996 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 51 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 317131 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 317402 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 317641 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 28 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 318293 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 318407 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 58 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 318438 | Paclitaxel | 0 | 0 | 0 | 0 | 60 | White | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 318569 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 39 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 319324 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 320538 | Paclitaxel | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 323721 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 65 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 324021 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 1 | 0 | 44 | Black or African American | NA | Not Hispanic or Latino |
| 326202 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 45 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 326433 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 327133 | Paclitaxel | 0 | 0 | 1 | 0 | 38 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 327142 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 59 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 327917 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 56 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 328160 | Paclitaxel | 1 | 0 | 0 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 329076 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 329941 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 330134 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 331192 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 1 | 42 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 332655 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 333145 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 335091 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 1 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 335536 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 67 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 340186 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 341238 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 27 | Asian;White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 342142 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 342959 | Paclitaxel + MK-2206 | 0 | 0 | 0 | 1 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 342996 | Paclitaxel | 1 | 0 | 0 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 343898 | Paclitaxel + MK-2206 | 0 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 345460 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 345483 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 50 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 345574 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 39 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 345907 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 61 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 347516 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 39 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 348009 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 349225 | Paclitaxel | 0 | 0 | 1 | 0 | 40 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 349330 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 50 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 349639 | Paclitaxel + Neratinib | 1 | 1 | 1 | 1 | 43 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 350331 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 54 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 353318 | Paclitaxel | 0 | 0 | 1 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 355292 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 355942 | Paclitaxel | 1 | 0 | 0 | 0 | 52 | White | NA | Not Hispanic or Latino |
| 356399 | Paclitaxel | 1 | 0 | 1 | 0 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 356431 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 356684 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 1 | 0 | 51 | Native Hawaiian or Pacific Islander | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 357017 | Paclitaxel | 1 | 0 | 0 | 0 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 357034 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 63 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 360937 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 361701 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 49 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 362150 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 44 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 362993 | Paclitaxel | 0 | 0 | 0 | 0 | 35 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 363669 | Paclitaxel | 1 | 0 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 366120 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 367682 | Paclitaxel | 0 | 0 | 1 | 0 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 369040 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 371528 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 70 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 373346 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 373672 | Paclitaxel | 0 | 0 | 0 | 0 | 67 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 374106 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 36 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 374121 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 375342 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 38 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 375455 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 375954 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 376676 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 377460 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 53 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 378401 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 378885 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 380239 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 380769 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 40 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 380972 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 28 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 382853 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 1 | 32 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 383456 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 1 | 50 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 384830 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 386664 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 388581 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 391942 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 395076 | Paclitaxel | 0 | 0 | 1 | 1 | 53 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 395249 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 395379 | Paclitaxel | 1 | 0 | 0 | 0 | 36 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 396723 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 72 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 397505 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 41 | White | NA | Hispanic or Latino |
| 399478 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 54 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 401215 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 402265 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 402384 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 405717 | Paclitaxel | 0 | 0 | 0 | 0 | 44 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 406190 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 407539 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 35 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 408692 | Paclitaxel | 0 | 0 | 1 | 1 | 25 | Asian;White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 409288 | Paclitaxel | 0 | 0 | 1 | 0 | 77 | Black or African American | NA | Not Hispanic or Latino |
| 410083 | T-DM1 + Pertuzumab | 0 | 1 | 0 | 1 | 55 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 411008 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 49 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 411684 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 411806 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 411950 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 61 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 412772 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 62 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 413211 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 413961 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 414256 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 38 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 414286 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 62 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 414844 | Paclitaxel | 1 | 0 | 1 | 0 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 414971 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 73 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 415039 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 416434 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 417474 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 63 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 417654 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 418593 | Paclitaxel | 1 | 0 | 0 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 419590 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 63 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 420523 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 421829 | Paclitaxel | 0 | 0 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 421917 | Paclitaxel | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 422013 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 32 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 422450 | Paclitaxel + Neratinib | 1 | 0 | 1 | 1 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 422454 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 45 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 423619 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 53 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 423979 | Paclitaxel | 1 | 0 | 0 | 0 | 54 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 424541 | Paclitaxel | 1 | 0 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 425173 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 426106 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 427321 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 1 | 51 | Black or African American | NA | Not Hispanic or Latino |
| 429220 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 52 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 430441 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 431061 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 432114 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 1 | 1 | 50 | White | NA | Not Hispanic or Latino |
| 433144 | Paclitaxel | 0 | 0 | 0 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 435279 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 435313 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 52 | Black or African American | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 436371 | Paclitaxel | 1 | 0 | 1 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 437162 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 437968 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 60 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 439489 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 442637 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 56 | Asian | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 442669 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 442981 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 443444 | Paclitaxel + Neratinib | 0 | 1 | 1 | 0 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 443708 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 55 | White | NA | Not Hispanic or Latino |
| 446263 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 53 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 451482 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 47 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 451816 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 452703 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 453596 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 57 | White | NA | Not Hispanic or Latino |
| 454808 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 56 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 455828 | Paclitaxel | 1 | 0 | 0 | 1 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 456432 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 45 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 456506 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 458196 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | Asian | NA | Not Hispanic or Latino |
| 459311 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 54 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 460642 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 45 | White | NA | Not Hispanic or Latino |
| 460776 | Paclitaxel | 1 | 0 | 0 | 1 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 460812 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 50 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 461824 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 0 | 36 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 462581 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 69 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 462582 | Paclitaxel | 1 | 0 | 0 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 462605 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 464547 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 465008 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 62 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 466267 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 467622 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 467686 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 1 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 472799 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 63 | American Indian or Alaska Native;White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 473365 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 473468 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 54 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 473505 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 56 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 474874 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 0 | 1 | 41 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 477816 | Paclitaxel | 1 | 0 | 0 | 0 | 39 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 477994 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 1 | 1 | 54 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 478055 | Paclitaxel | 1 | 0 | 0 | 0 | 31 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 478484 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 64 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 478655 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 479417 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 49 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 483667 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 483910 | Paclitaxel + Pembrolizumab | 0 | 0 | 0 | 0 | 50 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 484867 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 51 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 484894 | Paclitaxel | 1 | 0 | 0 | 0 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 485637 | Paclitaxel + Pembrolizumab | 0 | 0 | 0 | 0 | 54 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 489194 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 489504 | Paclitaxel | 0 | 0 | 1 | 1 | 47 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 489973 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 39 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 490023 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 490805 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 491526 | Paclitaxel | 1 | 0 | 0 | 0 | 71 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 491779 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 70 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 492612 | Paclitaxel | 0 | 0 | 1 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 493472 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 493519 | Paclitaxel | 1 | 0 | 0 | 0 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 493775 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 494022 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 0 | 58 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 494296 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 494946 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 495440 | Paclitaxel | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 496205 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 1 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 497010 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 498024 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 498985 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 25 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 500826 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 69 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 501303 | Paclitaxel + Trastuzumab | 0 | 1 | 1 | 1 | 47 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 502486 | Paclitaxel | 0 | 0 | 1 | 0 | 28 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 503034 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 0 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 504838 | Paclitaxel | 0 | 0 | 0 | 0 | 69 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 506623 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 69 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 507198 | Paclitaxel | 0 | 0 | 1 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 507249 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 509012 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 510543 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 62 | White | NA | Not Hispanic or Latino |
| 511851 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 48 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 515105 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 515141 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 43 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 515281 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 515284 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 36 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 515565 | Paclitaxel | 0 | 0 | 1 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 516763 | Paclitaxel + AMG 386 + Trastuzumab | 0 | 1 | 1 | 1 | 50 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 516834 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 517446 | Paclitaxel | 1 | 0 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 517870 | Paclitaxel | 0 | 0 | 1 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 518000 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 518576 | Paclitaxel + Ganetespib | 0 | 0 | 0 | 1 | 50 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 519738 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 520258 | Paclitaxel | 1 | 0 | 1 | 0 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 520471 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 1 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 520986 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 1 | 53 | Native Hawaiian or Pacific Islander | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 521860 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 522140 | Paclitaxel | 1 | 0 | 0 | 0 | 55 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 524170 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 527320 | Paclitaxel | 0 | 0 | 0 | 0 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 527581 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 528479 | Paclitaxel + Ganetespib | 0 | 0 | 0 | 0 | 63 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 528833 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 1 | 61 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 530095 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 45 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 531672 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 28 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 531988 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 532183 | Paclitaxel | 0 | 0 | 1 | 0 | 47 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 535415 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 535569 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 0 | 50 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 535779 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 536253 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 539291 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 47 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 539876 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 539904 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 45 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 540539 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 35 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 541165 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 49 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 542392 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 543795 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 547405 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 25 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 547892 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 48 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 549172 | Paclitaxel | 0 | 0 | 0 | 0 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 550157 | Paclitaxel | 0 | 0 | 1 | 1 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 550421 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 49 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 551795 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 552313 | Paclitaxel + Neratinib | 0 | 1 | 1 | 1 | 61 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 552549 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 553012 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 63 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 553141 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 1 | 70 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 554577 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 52 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 555214 | Paclitaxel + AMG 386 + Trastuzumab | 0 | 1 | 1 | 1 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 559021 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 1 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 559263 | Paclitaxel | 0 | 0 | 1 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 563681 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 23 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 563856 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 40 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 564234 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 564701 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 566011 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 567201 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 567907 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 52 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 568331 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 568953 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 570148 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 570380 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 570685 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 70 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 570966 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 1 | 0 | 51 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 571276 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 48 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 571995 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 572016 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 572235 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 54 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 572444 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 572731 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 1 | 34 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 572793 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 49 | White | NA | Hispanic or Latino |
| 573586 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 573605 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 573881 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 573919 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 0 | 65 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 574091 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 575372 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 575457 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 578975 | Paclitaxel + MK-2206 | 0 | 0 | 0 | 1 | 43 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 579881 | Paclitaxel | 1 | 0 | 0 | 0 | 32 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 580541 | Paclitaxel | 1 | 0 | 0 | 0 | 61 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 580632 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 581648 | Paclitaxel | 0 | 0 | 0 | 0 | 42 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 584561 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 586091 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 1 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 586207 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 587388 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 587604 | Paclitaxel | 0 | 0 | 1 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 587691 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 589502 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 1 | 67 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 590220 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 41 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 590299 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 591079 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 43 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 591180 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 591810 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 1 | 35 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 592535 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 596079 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 1 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 596458 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 597253 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 597873 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 36 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 597907 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 52 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 598798 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 0 | 46 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 598835 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 0 | 41 | American Indian or Alaska Native | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 600536 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 601489 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 0 | 54 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 602451 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 602943 | Paclitaxel | 0 | 0 | 1 | 1 | 38 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 604199 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 60 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 604326 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 604380 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 52 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 605713 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 38 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 607047 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 1 | 41 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 607843 | Paclitaxel | 1 | 0 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 609151 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 609642 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 609897 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 611662 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 55 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 613188 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 613961 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 614044 | Paclitaxel | 0 | 0 | 0 | 0 | 52 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 614434 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 1 | 56 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 615873 | Paclitaxel | 0 | 0 | 1 | 1 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 616994 | Paclitaxel | 1 | 0 | 1 | 0 | 43 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 618240 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 618717 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 29 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 618860 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 621179 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 622078 | Paclitaxel + Neratinib | 0 | 1 | 1 | 0 | 46 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 622315 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 48 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 622688 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 29 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 623086 | Paclitaxel + Neratinib | 1 | 0 | 1 | 0 | 34 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 623569 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 40 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 624777 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 52 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 625800 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 50 | White | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 625854 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 627118 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 627981 | Paclitaxel | 0 | 0 | 0 | 1 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 628692 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 628788 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 628823 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 629210 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 40 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 629371 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 629606 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 630758 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 631299 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 631337 | Paclitaxel | 1 | 0 | 0 | 0 | 28 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 632408 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 635632 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 46 | Asian | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 635862 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 37 | Asian,White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 636424 | Paclitaxel | 0 | 0 | 1 | 0 | 33 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 637051 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 52 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 637566 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 637752 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 638126 | Paclitaxel | 1 | 0 | 0 | 0 | 58 | White | NA | NA |
| 639663 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 640043 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 640463 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 1 | 31 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 640927 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 62 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 641246 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 641697 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 26 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 641977 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 57 | Native Hawaiian or Pacific Islander | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 644186 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 644609 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 67 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 646233 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 646600 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 35 | White | NA | Not Hispanic or Latino |
| 649198 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 0 | 0 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 650589 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 651145 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 651401 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 651541 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 652480 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 653325 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 653927 | Paclitaxel | 0 | 0 | 1 | 1 | 38 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 654021 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 654064 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 654956 | Paclitaxel + Neratinib | 0 | 1 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 655128 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 49 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 655703 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 655795 | Paclitaxel | 1 | 0 | 1 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 658541 | Paclitaxel | 1 | 0 | 1 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 660534 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 50 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 660915 | Paclitaxel + Neratinib | 1 | 0 | 1 | 0 | 54 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 661730 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 663144 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 48 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 663197 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 663467 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 0 | 45 | Black or African American | NA | Not Hispanic or Latino |
| 664111 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 664658 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 666147 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 27 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 666450 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 666715 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 668752 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 58 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 672734 | Paclitaxel + Ganitumab | 1 | 0 | 1 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 674897 | Paclitaxel | 0 | 0 | 1 | 0 | 50 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 676048 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 0 | 52 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 676365 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 676630 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 42 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 677910 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 45 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 677915 | Paclitaxel | 1 | 0 | 1 | 0 | 43 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 679787 | Paclitaxel | 0 | 0 | 1 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 680881 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 683173 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 683374 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 683457 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 50 | Black or African American | NA | Not Hispanic or Latino |
| 683896 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 685182 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 1 | 1 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 685753 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 685795 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 687288 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 687733 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 688291 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 56 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 688955 | Paclitaxel | 1 | 0 | 1 | 0 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 689076 | Paclitaxel | 1 | 0 | 0 | 0 | 32 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 689188 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 1 | 72 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 689452 | Paclitaxel | 0 | 0 | 1 | 0 | 63 | White | NA | Not Hispanic or Latino |
| 689480 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 54 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 690089 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 690410 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 69 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 691753 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 692885 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 40 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 695521 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 57 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 697098 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 697871 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 698094 | Paclitaxel | 1 | 0 | 0 | 0 | 53 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 700549 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 701790 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 65 | American Indian or Alaska Native | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 703401 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 703455 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 44 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 705381 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 706169 | Paclitaxel | 0 | 0 | 1 | 0 | 70 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 706418 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 706639 | Paclitaxel | 0 | 0 | 1 | 0 | 50 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 706943 | Paclitaxel + Neratinib | 0 | 1 | 1 | 0 | 52 | Black or African American | NA | Not Hispanic or Latino |
| 708387 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 29 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 709559 | Paclitaxel | 1 | 0 | 0 | 0 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 711476 | Paclitaxel | 1 | 0 | 0 | 1 | 47 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 712276 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 712785 | Paclitaxel | 0 | 0 | 1 | 0 | 50 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 712917 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 714205 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 719713 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 38 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 720065 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 721099 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 47 | White | NA | Hispanic or Latino |
| 723918 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 35 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 724293 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 41 | White | NA | Not Hispanic or Latino |
| 724384 | Paclitaxel | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 725455 | Paclitaxel + Trastuzumab | 0 | 1 | 1 | 0 | 49 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 726091 | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 43 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 726381 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 726940 | Paclitaxel | 0 | 0 | 0 | 0 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 727255 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 0 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 727804 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 43 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 728149 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 46 | White | NA | Not Hispanic or Latino |
| 728182 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 41 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 728287 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 1 | 66 | White | NA | Not Hispanic or Latino |
| 728714 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 729270 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 729732 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 732137 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 733276 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 54 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 733962 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 51 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 734997 | Paclitaxel | 1 | 0 | 1 | 0 | 38 | White | NA | Not Hispanic or Latino |
| 735673 | Paclitaxel | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 736721 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 738041 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 1 | 1 | 37 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 741535 | Paclitaxel | 1 | 0 | 0 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 742477 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 745633 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 746265 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 35 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 746731 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 46 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 748583 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 67 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 748611 | Paclitaxel | 1 | 0 | 1 | 1 | 59 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 749097 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 752372 | Paclitaxel | 1 | 0 | 0 | 0 | 59 | White | Above categories not applicable AND Age < 50 | Hispanic or Latino |
| 752469 | Paclitaxel | 0 | 0 | 1 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 753109 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 755914 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 756412 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 759015 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 36 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 759418 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 760011 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 760901 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 765671 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 41 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 765773 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 49 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 766301 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 766967 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 1 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 767081 | T-DM1 + Pertuzumab | 0 | 1 | 0 | 1 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 767934 | Paclitaxel | 0 | 0 | 1 | 1 | 68 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 768214 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 51 | White | NA | Not Hispanic or Latino |
| 769972 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 771151 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 771443 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 51 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 771813 | Paclitaxel | 0 | 0 | 1 | 0 | 49 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 774840 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 775346 | Paclitaxel | 1 | 0 | 0 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 778020 | Paclitaxel + Neratinib | 1 | 0 | 1 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 778527 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 44 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 779739 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 1 | 47 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 780272 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 781335 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 0 | 57 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 781642 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 61 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 782334 | Paclitaxel | 1 | 0 | 0 | 0 | 46 | Black or African American | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 783427 | Paclitaxel | 1 | 0 | 1 | 1 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 783578 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 48 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 783764 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 54 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 783771 | Paclitaxel | 1 | 0 | 1 | 0 | 31 | Black or African American | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 786003 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 786480 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 41 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 786753 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 0 | 59 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 787415 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 788149 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 0 | 1 | 57 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 789497 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 54 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 790070 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 44 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 790397 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 790722 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 791321 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 791944 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 792181 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 792412 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 793155 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 793684 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 48 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 794128 | Paclitaxel + Ganitumab | 0 | 0 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 794428 | Paclitaxel | 0 | 0 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 795996 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 1 | 1 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 796558 | Paclitaxel | 0 | 0 | 0 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 797427 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 797499 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 52 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 797639 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 798604 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 799149 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 800447 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 800710 | Paclitaxel | 0 | 0 | 1 | 0 | 29 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 801641 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 53 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 802105 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 802308 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 52 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 802778 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 803514 | Paclitaxel | 1 | 0 | 0 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 803677 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 804233 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 804979 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 47 | Asian | NA | Not Hispanic or Latino |
| 805136 | Paclitaxel + AMG 386 + Trastuzumab | 0 | 1 | 1 | 0 | 52 | Black or African American | NA | Not Hispanic or Latino |
| 808714 | Paclitaxel | 0 | 0 | 1 | 0 | 69 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 809037 | Paclitaxel | 1 | 0 | 0 | 0 | 52 | White | Perimenopausal (6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 809649 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 1 | 44 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 810965 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 812089 | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 814299 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 40 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 815421 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 68 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 815493 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 37 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 819622 | Paclitaxel | 1 | 0 | 0 | 0 | 53 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 820348 | Paclitaxel | 1 | 0 | 1 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 820807 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 1 | 50 | Black or African American | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 823618 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 824234 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 1 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 824350 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 824512 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 68 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 825363 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 29 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 828199 | Paclitaxel + Neratinib | 1 | 0 | 0 | 0 | 43 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 829491 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 830486 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 36 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 830958 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 55 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 831702 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 42 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 831848 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 832056 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 833536 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 1 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 834418 | Paclitaxel | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 835137 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 71 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 835658 | Paclitaxel + Neratinib | 1 | 0 | 1 | 1 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 836114 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 836983 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 839274 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 1 | 0 | 68 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 840501 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 841336 | Paclitaxel | 1 | 0 | 0 | 0 | 47 | Black or African American | NA | Not Hispanic or Latino |
| 843554 | Paclitaxel | 0 | 0 | 1 | 0 | 31 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 845079 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 845147 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 46 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 845663 | Paclitaxel | 1 | 0 | 0 | 0 | 32 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 845783 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 34 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 846156 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 847272 | Paclitaxel | 0 | 0 | 1 | 0 | 51 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 847753 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 1 | 54 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 848003 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 848371 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 32 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 849605 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 851180 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 50 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 851223 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 851488 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 63 | White | NA | Not Hispanic or Latino |
| 856159 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 46 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 857165 | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 859699 | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 1 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 860243 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 860901 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 861745 | Paclitaxel + MK-2206 | 1 | 0 | 1 | 0 | 31 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 862244 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 863161 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 865416 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 866660 | Paclitaxel | 1 | 0 | 0 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 870077 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 60 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 872188 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 60 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 873686 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 875089 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 876511 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 877463 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 45 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 879224 | Paclitaxel | 0 | 0 | 0 | 0 | 33 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 882538 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 882553 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 883696 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 0 | 27 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 883886 | Paclitaxel + Neratinib | 0 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 884011 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 66 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 884266 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 49 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 885590 | Paclitaxel | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 885871 | Paclitaxel | 0 | 0 | 1 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 887594 | Paclitaxel + MK-2206 | 0 | 0 | 1 | 1 | 39 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 889049 | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 36 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 889225 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 889721 | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 890372 | Paclitaxel + Ganitumab | 0 | 0 | 0 | 0 | 39 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 890414 | Paclitaxel | 0 | 0 | 0 | 1 | 55 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 891645 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 37 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 892390 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 893874 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 894128 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 57 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 894491 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 1 | 0 | 49 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 894673 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 59 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 895653 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 896621 | Paclitaxel | 1 | 0 | 0 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 896852 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 896939 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 63 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 898618 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 54 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 899381 | Paclitaxel | 1 | 0 | 1 | 1 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 899692 | Paclitaxel | 0 | 0 | 1 | 1 | 57 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 900959 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 901705 | Paclitaxel | 1 | 0 | 0 | 0 | 42 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 903880 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 53 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 904269 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 905264 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 0 | 69 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 906042 | Paclitaxel | 1 | 0 | 0 | 0 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 906795 | Paclitaxel + Trastuzumab | 1 | 1 | 1 | 0 | 29 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 910188 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 910706 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 37 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 912836 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 57 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 913225 | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 51 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 913527 | Paclitaxel | 0 | 0 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 914968 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 30 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 916586 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 46 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 916645 | Paclitaxel | 1 | 0 | 0 | 1 | 50 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 917762 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 35 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 918979 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 60 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 920479 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 45 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 922872 | Paclitaxel | 1 | 0 | 0 | 0 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 923968 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 1 | 40 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 924071 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 57 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 924812 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 0 | 60 | White | NA | Hispanic or Latino |
| 924868 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 924895 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 39 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 925691 | Paclitaxel + Neratinib | 0 | 1 | 0 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 928170 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 67 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 928446 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 39 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 928815 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 38 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 929391 | Paclitaxel | 0 | 0 | 1 | 0 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 929980 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 1 | 1 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 930172 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 44 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 930853 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 1 | 45 | Native Hawaiian or Other Pacific Islande | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 930903 | Paclitaxel + Ganetespib | 1 | 0 | 1 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 932200 | Paclitaxel | 1 | 0 | 1 | 0 | 24 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 934459 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 0 | 70 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 934906 | Paclitaxel | 0 | 0 | 1 | 0 | 32 | Asian;White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 935460 | Paclitaxel | 0 | 0 | 1 | 0 | 65 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 938719 | Paclitaxel | 1 | 0 | 1 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 940186 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 1 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 941191 | Paclitaxel + Neratinib | 1 | 1 | 0 | 0 | 52 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 941926 | Paclitaxel | 1 | 0 | 0 | 0 | 51 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 942017 | Paclitaxel | 1 | 0 | 1 | 0 | 44 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 943633 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 943879 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 40 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 944419 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 38 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 944536 | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 58 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 946927 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 63 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 947398 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 949444 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 34 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 950131 | Paclitaxel | 1 | 0 | 0 | 1 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 950742 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 40 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 953262 | Paclitaxel + Neratinib | 1 | 0 | 1 | 0 | 36 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 953885 | T-DM1 + Pertuzumab | 1 | 1 | 1 | 0 | 42 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 955035 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 955953 | Paclitaxel + MK-2206 + Trastuzumab | 0 | 1 | 0 | 1 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 957408 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 29 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 959366 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 65 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 960029 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 43 | Native Hawaiian or Pacific Islander | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 960490 | Paclitaxel + Pembrolizumab | 0 | 0 | 1 | 1 | 36 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 960963 | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 962153 | Paclitaxel + AMG 386 + Trastuzumab | 1 | 1 | 1 | 0 | 55 | White | NA | Hispanic or Latino |
| 962472 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 29 | Black or African American | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 962664 | Paclitaxel | 0 | 0 | 1 | 1 | 30 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 962827 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 963303 | Paclitaxel | 1 | 0 | 0 | 0 | 37 | Asian;White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 963604 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 965265 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 966016 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 1 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 970839 | Paclitaxel | 1 | 0 | 1 | 0 | 58 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 971492 | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 32 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 972307 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 973837 | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 47 | Asian | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 974181 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 41 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 974618 | Paclitaxel + AMG 386 | 0 | 0 | 0 | 1 | 67 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 981461 | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 44 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 981664 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 50 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 982086 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 982505 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 51 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 983841 | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 52 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 986734 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 33 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 987728 | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | Asian | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 987914 | Paclitaxel | 0 | 0 | 1 | 0 | 57 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 987995 | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 56 | White | Above categories not applicable AND Age > 50 | Hispanic or Latino |
| 988443 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 988665 | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 49 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 990443 | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 53 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 991818 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 1 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 992609 | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 994987 | Paclitaxel + ABT 888 + Carboplatin | 1 | 0 | 0 | 0 | 62 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 995480 | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 46 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 997702 | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 31 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 999264 | Paclitaxel + Pertuzumab + Trastuzumab | 0 | 1 | 1 | 1 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 999733 | Paclitaxel + MK-2206 | 1 | 0 | 0 | 0 | 47 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
MatchPatients: Genomics and Radiomics
Identify overlapping patients between genomics (gene expression) and radiomics (MRI scans) datasets.
# Prepare genomic clinical data
Genomics_clin <- clin
Genomics_clin$patientid <- sub("^X", "", Genomics_clin$patientid) # Remove "X" prefix
rownames(Genomics_clin) <- Genomics_clin$patientid
colnames(expr) <- sub("^X", "", colnames(expr))
# Identify common patients
common_patients <- intersect(Genomics_clin$patientid, Radiomics_clin$Patient_ID)
# Print count of common patients
cat("Patients with both microarray and MRI data:", length(common_patients), "\n")Patients with both microarray and MRI data: 982
# Venn diagram
venn_data <- list(Genomics = Genomics_clin$patientid, Radiomics = Radiomics_clin$Patient_ID)
ggvenn(venn_data, fill_color = c("#A6CEE3", "#FB9A99"), stroke_size = 0.5, set_name_size = 4) +
ggtitle("Overlap of Genomics (Microarray) and Radiomics (MRI) Patient IDs") +
theme(plot.title = element_text(hjust = 0.5, size = 12, face = "bold"), plot.background = element_rect(fill = "white"), panel.background = element_blank())
Merge Genomics & Radiomics Data
Merging both datasets based on common patient IDs.
Adjustments:
- Prefix MRI columns with
"Radiomics_"
- Ensure consistent patient IDs
- Save merged dataset for analysis
# Add prefix to radiomics columns
colnames(Radiomics_clin)[-which(colnames(Radiomics_clin) == "Patient_ID")] <- paste0("Radiomics_", colnames(Radiomics_clin)[-which(colnames(Radiomics_clin) == "Patient_ID")])
# Merge datasets
merged_clin <- merge(Genomics_clin, Radiomics_clin, by.x = "patientid", by.y = "Patient_ID")
# Sort by patient ID
merged_clin <- merged_clin[order(merged_clin$patientid), ]
# Save dataset as CSV
write.csv(merged_clin, file = file.path(here(), "data/results/radiogenomics", "combined_clin_radiogenomic.csv"), row.names = FALSE)
# Display merged dataset with scrolling
kable(head(merged_clin,50), caption = "Merged Clinical Data (Genomics & Radiomics)") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| patientid | sex | age | cancer_type | histo | tissueid | stage | response.other.info | recist | response | treatment | dna | rna | survival_time_pfs | event_occurred_pfs | survival_time_os | event_occurred_os | survival_unit | survival_type | TMB_raw | nsTMB_raw | indel_TMB_raw | indel_nsTMB_raw | TMB_perMb | nsTMB_perMb | indel_TMB_perMb | indel_nsTMB_perMb | CIN | CNA_tot | AMP | DEL | treatmentid | dna_info | rna_info | Arm..short.name. | pCR | HR | HER2 | MP2 | Immune. | DRD. | BP.subtype | Receptor.Subtype | I.SPY2.Subtypes | RPS.5 | BP.HER2.2..6 | BP.HER2.2..4 | BP.HER2.2..Immune.5 | BP.HR.HER2.2..Immune.6 | HER2.3.state..3. | BP.HR.HER2.3..6 | BP.HER2.3..6 | BP.Immune.HER2.3..5 | BP.HR.Immune.HER2.3..6 | DRD.Immune.HER2.3..6 | RPS.7..i.e..DRD.Immune.HR.HER2.3..7. | ICS5_score | Chemokine12_score | Module5_TcellBcell_score | STAT1_sig | Module3_IFN_score | Dendritic_cells | B_cells | Mast_cells | Module11_Prolif_score | MP_index_adj…1. | Basal_Index | PARPi7_score | PARPi7_plus_MP2 | VCpred_TN | STMN1_dat | HER2_Index | Mod7_ERBB2 | ERBB2.Y1248 | EGFR.Y1173 | mTOR.S2448 | IGF1R_dat | TIE2.Y992 | Mod10_ECM | RPL24_dat | LYMPHS_PCA_16704732 | Luminal_Index | ER_PGR_avg | PAM50.Subtype | TNBCtype_7class | TNBC_BB_4class | Radiomics_Arm | Radiomics_HR | Radiomics_HER2 | Radiomics_MP | Radiomics_pCR | Radiomics_Age_at_Screening | Radiomics_Race | Radiomics_menopausal_status | Radiomics_ethnicity |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 100899 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20870 | 0.796000 | 0.63020 | 1.036000 | 0.193300 | -0.08080 | -0.064170 | -0.06758 | -0.38930 | -0.07714 | 1.22300 | 0.99240 | 0.86020 | 0.191100 | -1.06900 | -0.6318 | -0.79760 | NA | NA | NA | -0.7939000 | NA | 0.28970 | -0.24500 | -0.823600 | -0.72510 | -0.497100 | Basal | BL2 | LAR | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 53 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 102011 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.21900 | 0.509100 | 0.65020 | 0.299100 | -0.362000 | 0.75260 | 0.426100 | -0.54970 | 1.17800 | 1.37800 | 1.11000 | 0.66820 | 0.93300 | -0.524900 | 0.20960 | -0.5996 | -0.67160 | NA | NA | NA | -0.3970000 | NA | -1.99300 | 3.00200 | 2.261000 | -0.74760 | -0.191700 | Basal | NA | NA | Paclitaxel + Ganetespib | 1 | 0 | 1 | 1 | 32 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 102212 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 | NA | NA | MK2206 | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.10000 | 0.978200 | 1.43200 | 0.367300 | 0.253600 | 0.59370 | 2.008000 | 1.25100 | -2.17800 | -1.29500 | 0.90250 | -0.28720 | -0.58080 | 1.100000 | -0.94570 | -0.4772 | -0.74750 | NA | NA | NA | 0.1968000 | NA | 0.98770 | 0.78080 | -0.686600 | 0.01676 | 0.118600 | Normal | MSL | MES | Paclitaxel + MK-2206 | 0 | 0 | 0 | 0 | 26 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 103693 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | HR+HER2-/BP_Basal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | -0.83620 | -1.249000 | -1.12600 | -1.293000 | -1.353000 | -0.39820 | -0.444500 | 0.09109 | -0.84910 | -0.21730 | -0.26370 | -0.05050 | -0.10260 | -0.521800 | -0.94400 | -0.5073 | -0.31860 | -0.2776 | -0.26030 | 0.07633 | 0.2533000 | NA | 0.40100 | 0.25040 | -0.293600 | -0.62400 | -0.556700 | Her2 | NA | NA | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 103939 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.87290 | -1.231000 | -1.18500 | -1.959000 | -1.958000 | -0.80620 | -0.649100 | -0.48040 | 1.23000 | -1.00400 | -1.16000 | -0.76310 | -0.93200 | -0.730200 | 0.69100 | -0.6237 | 0.09161 | -0.3335 | -0.28550 | -0.15270 | 0.9003000 | NA | -0.91140 | 0.54750 | 1.307000 | 1.58500 | 2.070000 | LumB | NA | NA | Paclitaxel | 1 | 0 | 0 | 0 | 51 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 104268 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 0 | 0 | 1 | 0 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -1.56300 | -1.605000 | -1.33500 | -1.019000 | 0.868600 | -0.61490 | -1.063000 | -1.00500 | 1.28400 | 0.99390 | 0.98400 | -1.58700 | -1.17000 | -2.076000 | 0.03416 | -0.2965 | -0.27290 | -0.3607 | -0.31670 | 0.27420 | 0.8947000 | NA | -0.61660 | -0.93500 | 0.044230 | -0.54810 | -0.728500 | Basal | UNS | BLIS | Paclitaxel | 0 | 0 | 1 | 0 | 50 | Black or African American | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 104384 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.22970 | 0.013520 | -0.25040 | -0.004404 | -1.204000 | 0.10850 | 0.032630 | 0.06288 | -0.07652 | 0.74950 | 1.02600 | 0.45570 | 0.58780 | -0.000986 | -0.23910 | -0.6197 | -1.16600 | -0.3734 | -0.38780 | -1.51100 | -0.5201000 | NA | 0.73450 | -0.66640 | -0.746000 | -0.67450 | -0.801800 | Basal | NA | NA | Paclitaxel + Pembrolizumab | 1 | 0 | 1 | 0 | 42 | American Indian or Alaska Native | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 105286 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.33670 | 0.147300 | -0.06257 | -0.698500 | -0.095280 | 0.55290 | -0.486900 | 2.62900 | -1.70900 | -1.83500 | -0.91570 | -0.86400 | -1.22800 | -1.032000 | -1.20400 | -0.5033 | -0.76620 | NA | NA | NA | 0.4573000 | NA | 1.20900 | 0.90320 | 0.114800 | 1.02600 | 0.980500 | LumA | NA | NA | Paclitaxel + Ganitumab | 1 | 0 | 0 | 0 | 65 | White | NA | Not Hispanic or Latino |
| 105513 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.42990 | -0.086500 | -0.03396 | -0.347600 | -0.973400 | -0.09498 | 0.300300 | -1.61100 | 1.17300 | 0.86810 | 0.02009 | 0.58810 | 0.73500 | 0.501700 | 1.10600 | -0.5595 | -0.03981 | -0.4617 | -0.35570 | -0.38710 | -1.6900000 | 3.0940 | -1.26800 | 0.78080 | -0.490400 | -0.72790 | -1.084000 | Her2 | NA | NA | Paclitaxel + AMG 386 | 1 | 0 | 1 | 1 | 48 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 107700 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 + Trastuzumab | NA | NA | MK2206 | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.89600 | -0.263100 | -0.64080 | -0.435200 | -0.206300 | -0.09306 | -0.679500 | 0.75780 | -0.01925 | -1.27700 | -1.04500 | -1.48900 | -1.64600 | -1.074000 | -0.80560 | 1.0560 | -0.12160 | -0.4019 | -0.42400 | -1.15400 | 1.6790000 | 0.4305 | 0.22030 | -1.96700 | 0.115800 | 0.67150 | 0.858000 | LumB | NA | NA | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 0 | 0 | 68 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 108939 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 0 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.83290 | 0.605100 | 0.54100 | -0.004226 | -0.844100 | 0.90340 | 0.281000 | 1.14000 | -0.37790 | -0.41850 | -0.81740 | -0.05181 | -0.15370 | 0.272100 | -0.73640 | 2.2950 | 1.89800 | 2.0010 | 2.44000 | 0.33000 | -0.2396000 | -0.4657 | 0.87950 | 0.67270 | -0.608400 | -0.59870 | -0.101200 | Her2 | NA | NA | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 34 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 108969 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 0 | 1 | 0 | 0 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.10150 | -0.923000 | -0.87110 | -1.483000 | -1.943000 | 0.33620 | 0.229600 | -0.32130 | -0.31720 | -0.96840 | -1.28400 | -1.15100 | -1.26800 | -1.205000 | -1.39900 | 2.1950 | 1.54900 | 2.1600 | 2.12700 | 0.95230 | -0.3313000 | -0.4062 | -0.70670 | 0.85050 | 1.090000 | -0.40480 | 0.458300 | LumB | NA | NA | Paclitaxel + Neratinib | 0 | 1 | 0 | 1 | 64 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 109623 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -1.77200 | -2.232000 | -2.53000 | -2.028000 | -1.309000 | -1.51700 | -1.585000 | 0.23080 | -2.04900 | -1.16600 | -1.37400 | 0.74060 | 0.36590 | -1.197000 | -0.86970 | -0.4812 | 0.52240 | NA | NA | NA | 3.8050000 | NA | -1.74700 | 0.66270 | 1.731000 | 1.43900 | 0.432600 | LumA | NA | NA | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 109874 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.12610 | 0.568900 | 0.35200 | 0.722900 | 0.203500 | -0.24450 | 0.583700 | -0.30340 | -0.35630 | 0.62370 | 0.95030 | 1.29100 | 1.30000 | 0.726100 | 0.22670 | -0.5856 | -0.62310 | -0.3947 | -0.42990 | -0.38710 | -0.4627000 | -1.2890 | 1.18700 | -0.14400 | -1.535000 | -0.55090 | -1.044000 | Basal | UNS | LAR | Paclitaxel + AMG 386 | 0 | 0 | 1 | 1 | 43 | Asian | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 109980 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 0 | 1 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.96250 | 0.812700 | 1.01400 | 0.665500 | 1.310000 | -0.42670 | 1.282000 | 1.12300 | -0.63020 | -0.86060 | -0.62060 | -0.17260 | -0.37090 | 0.925600 | -0.68740 | 2.1550 | 3.19000 | 6.2610 | 6.53300 | 0.59010 | 0.0381300 | -0.6191 | -1.06000 | 0.60440 | 1.434000 | 0.04486 | 0.505500 | LumB | NA | NA | Paclitaxel + Neratinib | 1 | 1 | 0 | 1 | 53 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 111004 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Luminal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -0.21570 | 0.534000 | 0.29740 | 0.740600 | 0.913900 | 0.47210 | -0.424200 | 1.60100 | -0.89370 | -1.22400 | -0.77800 | 0.48380 | 0.12310 | 0.014020 | -0.38120 | -0.5555 | -1.17500 | -0.3340 | -0.38080 | 0.70050 | 0.3983000 | NA | 2.31800 | -1.44300 | -0.410600 | 0.40740 | -0.256300 | LumB | NA | NA | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | NA | NA | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111038 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.30500 | 1.818000 | 1.45100 | 1.784000 | 1.898000 | 0.35760 | 0.803100 | -0.30500 | 0.61270 | 1.23500 | 1.17500 | -0.64410 | -0.27040 | 0.645000 | 0.10430 | -0.5796 | -0.56320 | -0.4160 | -0.31510 | 1.35700 | -1.2370000 | 0.4715 | -0.88780 | -1.55500 | -0.308700 | -1.12400 | -0.861600 | Basal | IM | BLIA | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 28 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111344 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 1 | 0 | 1 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.16470 | 0.336100 | 0.18070 | 0.804400 | 2.632000 | -0.46240 | -0.011610 | -0.98070 | 0.31490 | 0.39010 | -1.05100 | -0.57770 | -0.42100 | -0.409600 | 0.08036 | -0.6016 | -0.62220 | -0.4043 | -0.41640 | 0.49830 | 0.0001858 | 0.6159 | -1.95600 | -0.21230 | 0.285900 | 0.63220 | 2.248000 | LumB | NA | NA | Paclitaxel + AMG 386 | 1 | 0 | 1 | 0 | 55 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 111646 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -0.36890 | -0.703600 | -0.41630 | -0.438700 | 0.796800 | -0.74150 | 0.262300 | 1.67100 | -0.87980 | -1.60500 | -1.30600 | -0.45840 | -0.80980 | -0.199800 | -0.86370 | -0.4250 | -0.46910 | NA | NA | NA | 1.2140000 | NA | 0.25080 | -0.55370 | 0.254300 | 1.58200 | 2.060000 | LumB | NA | NA | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 66 | White | NA | Not Hispanic or Latino |
| 111674 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 1 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.23240 | -0.214500 | -0.01483 | 0.011390 | 0.195800 | 1.22300 | -0.499900 | 0.46760 | 0.29220 | 0.55540 | 0.90810 | 0.98660 | 1.01200 | 0.272300 | 1.13800 | -0.5113 | -0.32800 | -0.4779 | -0.56270 | -2.69100 | -0.4783000 | 9.2790 | 0.60930 | -0.20510 | -0.879600 | -0.82630 | -0.652500 | Basal | MSL | MES | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 0 | 1 | 30 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 111881 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 1 | 1 | 1 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.34970 | -0.216600 | -0.53990 | -0.268500 | 0.139100 | -1.58300 | -0.892400 | 0.46200 | 0.70120 | 0.72430 | -0.93820 | -1.03000 | -0.74060 | -0.076860 | -0.35420 | 2.2570 | 3.04100 | 3.4960 | 3.61400 | 0.70720 | -0.1055000 | -0.5253 | -0.08600 | 0.08368 | 0.482700 | 0.31460 | 0.233100 | LumB | NA | NA | Paclitaxel + Neratinib | 1 | 1 | 1 | 1 | 37 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 112606 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trastuzumab | NA | NA | Ctr | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | 0.02571 | 0.159700 | -0.09021 | 0.010330 | -0.480800 | 0.40990 | 0.071040 | 0.99270 | -0.71140 | -1.09800 | -0.98030 | -3.14900 | -3.07900 | -0.537200 | -0.70060 | -0.4952 | 0.34880 | -0.2613 | -0.29810 | 0.62860 | 4.4520000 | -0.7779 | 1.15400 | -1.97400 | 0.199900 | 0.69400 | 2.501000 | LumA | NA | NA | Paclitaxel + Trastuzumab | 1 | 1 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 114087 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | -1.11700 | -1.409000 | -1.25100 | -0.820400 | 0.700700 | -1.52300 | -1.067000 | -0.26100 | -0.37050 | -0.72760 | -1.98400 | -1.11800 | -1.17900 | -1.218000 | 0.26500 | -0.6277 | -0.31540 | -0.3603 | -0.36150 | 0.37120 | 0.8584000 | NA | 0.03222 | -0.39490 | 0.122100 | 1.50900 | 2.133000 | LumB | NA | NA | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 46 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 115638 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.36310 | 0.158100 | 0.49560 | 0.805100 | 0.082480 | 0.78570 | 0.006451 | -1.35500 | 1.57100 | 0.89320 | 1.26800 | 0.14550 | 0.34750 | 0.013020 | 0.62470 | -0.6197 | -0.43430 | NA | NA | NA | -1.6680000 | NA | -2.19600 | 1.47900 | 0.274800 | -0.84600 | -0.772400 | Basal | IM | BLIA | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 34 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 115987 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 1 | 0 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2low/Immune-/DRD.v3- | HR-/HER2low/Immune-/DRD.v3- | -2.36500 | -2.138000 | -2.12400 | -2.721000 | -2.767000 | -0.14640 | -1.600000 | -0.70550 | 1.24000 | 0.81780 | 1.15500 | -0.09058 | 0.11860 | -2.030000 | 0.62820 | -0.1399 | -0.92390 | NA | NA | NA | -0.3328000 | NA | -0.23560 | 0.37530 | 0.442800 | -0.85720 | -1.030000 | Basal | M | BLIS | Paclitaxel + Ganitumab | 0 | 0 | 1 | 0 | 42 | White | Above categories not applicable AND Age < 50 | Not Hispanic or Latino |
| 116165 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | IO+chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pembrolizumab | NA | NA | Pembro | 0 | 1 | 0 | 0 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20900 | -0.333500 | 0.14560 | 0.040340 | 0.140200 | -0.56650 | 0.092170 | -0.53190 | 0.17420 | -0.45810 | -0.93540 | -0.81700 | -0.84440 | 0.678000 | -0.44900 | -0.4952 | -0.36510 | -0.1809 | -0.28000 | 3.76600 | 0.2887000 | NA | -0.72200 | -1.82000 | -0.647500 | 1.06500 | 1.511000 | LumB | NA | NA | Paclitaxel + Pembrolizumab | 1 | 0 | 0 | 0 | 55 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 116603 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 0 | 0 | 1 | 1 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.65710 | 0.212100 | 0.67640 | 0.794700 | 0.119800 | -0.42820 | -0.498600 | -1.72000 | 0.63850 | 1.15900 | 0.82100 | 0.05654 | 0.33430 | -0.527500 | 0.02534 | -0.1259 | -0.52070 | -0.2361 | -0.12090 | 1.92900 | -0.3574000 | 0.3903 | -1.36700 | 0.66130 | -0.401200 | -0.78980 | -1.155000 | Basal | UNS | BLIA | Paclitaxel | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 117424 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.20130 | 0.023940 | -0.05377 | 0.333600 | 0.006988 | -0.25950 | -0.611200 | 0.38510 | 0.17090 | 0.69920 | 0.66920 | 1.12200 | 1.16900 | 0.822300 | 1.74100 | -0.5675 | -0.93290 | -0.3061 | -0.30020 | -0.03717 | -0.3578000 | -0.4342 | 1.17300 | 0.98710 | -0.170100 | -0.25300 | -0.690800 | Basal | MSL | LAR | Paclitaxel + Neratinib | 0 | 0 | 1 | 1 | 33 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 117707 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 1 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.34680 | 0.770100 | 0.25000 | 0.650700 | 1.935000 | -0.77060 | -0.413700 | -1.13400 | 0.78900 | 0.95430 | 1.09400 | 0.19930 | 0.41040 | 0.065220 | 0.10800 | -0.5675 | -0.63500 | NA | NA | NA | -0.5770000 | NA | -0.75800 | 0.46640 | 0.134000 | -0.94430 | -0.934600 | Basal | BL1 | BLIS | Paclitaxel + Ganetespib | 0 | 0 | 1 | 1 | 50 | Black or African American | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 118307 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | NA | NA | NA | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.29490 | -0.726600 | -0.22270 | -0.572000 | 0.327700 | -0.98270 | 0.360600 | -0.93590 | 1.01500 | 1.20200 | 1.08800 | 2.00500 | 2.07900 | 0.310300 | 1.24000 | -0.6237 | -0.58950 | -0.4582 | -0.40310 | 0.12270 | -0.6494000 | -1.4060 | -0.76410 | 0.75100 | -0.661400 | -0.62680 | -0.714900 | Basal | BL1 | BLIS | Paclitaxel + AMG 386 | 0 | 0 | 1 | 0 | 44 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 119928 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 0 | 0 | 1 | 1 | 0 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | -0.25220 | 0.368100 | -0.49930 | 0.340400 | -0.424700 | -0.01930 | -0.482000 | -0.18170 | 1.28400 | 1.03000 | 0.49500 | -0.22080 | 0.05538 | -1.117000 | 1.27900 | -0.5836 | -1.18800 | NA | NA | NA | -1.6050000 | NA | 0.41000 | 0.67130 | 0.976700 | -0.39070 | -1.037000 | Basal | BL2 | LAR | Paclitaxel + Ganetespib | 0 | 0 | 1 | 0 | 39 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 120001 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 0 | 0 | 0 | 0 | 0 | 0 | Basal-type | TN | TN/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -0.96740 | -0.349700 | -0.35340 | -0.048590 | 0.915500 | -0.38410 | -0.624100 | -1.02500 | 1.01300 | 0.50510 | 0.93620 | -0.79060 | -0.58180 | -0.629800 | 0.64760 | -0.5515 | -0.59680 | -0.4545 | -0.43160 | -0.76680 | -0.2782000 | -0.2686 | 0.17130 | -1.24200 | -0.572300 | -0.59590 | -0.582600 | Basal | BL1 | BLIS | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 53 | Black or African American | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 120422 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2=0 | HR+/HER2=0 | HER2=0/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.37600 | 1.118000 | 1.15300 | 0.250200 | -0.468100 | 2.55500 | 1.414000 | -0.02934 | 0.48120 | 0.55180 | 1.13000 | 2.08500 | 1.98900 | 1.330000 | 2.90300 | -0.5434 | -0.98200 | NA | NA | NA | -0.4173000 | NA | 0.84000 | 0.36400 | -1.065000 | -0.66330 | -0.510900 | Basal | NA | NA | Paclitaxel + Ganitumab | 1 | 0 | 1 | 1 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 122287 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 1 | 1 | 1 | 1 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 0.65590 | 0.433900 | 0.20350 | 0.461600 | 0.791700 | -0.35650 | 0.553700 | 0.76490 | -0.60180 | 0.01271 | -0.51100 | 1.24200 | 1.10500 | 0.338800 | -0.38710 | 2.2610 | 2.72200 | 1.5160 | 2.01800 | -0.40390 | -0.9569000 | NA | 0.56190 | -1.09200 | -2.047000 | -0.95550 | -0.926500 | Her2 | NA | NA | T-DM1 + Pertuzumab | 1 | 1 | 1 | 1 | 54 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Hispanic or Latino |
| 122579 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2low/BP_Luminal/Immune- | HER2low/BP_Luminal/Immune- | HER2low/Immune-/DRD.v3- | HR+/HER2low/Immune-/DRD.v3- | 0.35360 | -0.023670 | 0.02669 | 0.373700 | 0.543700 | -0.35840 | -0.517000 | 0.33200 | -0.94680 | -1.16200 | -1.27300 | -1.35300 | -1.49600 | 0.740500 | -1.50700 | -0.4370 | -0.25600 | -0.3575 | -0.38600 | 0.17210 | -1.1870000 | NA | -0.88580 | -0.74200 | 0.653100 | 1.07100 | 0.545900 | LumB | NA | NA | Paclitaxel | 1 | 0 | 0 | 0 | 57 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 122795 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.02600 | 0.918500 | 0.85100 | -0.147900 | -0.983600 | 0.62740 | 1.071000 | 1.05400 | -1.67400 | -2.21900 | 0.86320 | -0.21630 | -0.74690 | 0.454000 | -1.00100 | -0.6036 | -0.88950 | NA | NA | NA | 0.1935000 | NA | 2.03200 | 0.16340 | -0.105200 | -0.38230 | -0.316300 | Normal | MSL | LAR | Paclitaxel + Ganitumab | 0 | 0 | 0 | 0 | 45 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 123660 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trastuzumab | NA | NA | Ctr | 0 | 0 | 1 | 0 | 0 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -0.93020 | -1.299000 | -0.71420 | -0.901100 | -0.427300 | -0.56650 | -0.537800 | 0.19560 | -1.47300 | -0.86060 | -0.87920 | 1.76600 | 1.35400 | -0.807600 | 0.23710 | 2.2410 | 1.59200 | 2.2400 | 2.83400 | 0.47630 | -0.1896000 | 1.5030 | 0.62890 | -0.29760 | -0.938000 | -0.50310 | 0.005983 | LumA | NA | NA | Paclitaxel + Trastuzumab | 0 | 1 | 0 | 0 | 71 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 125130 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 0 | 1 | 1 | 1 | 0 | HER2-type | HR-HER2+ | HR-HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | 1.19800 | 0.561800 | 0.65390 | 0.191900 | -0.451200 | -0.27830 | 1.558000 | -0.63220 | 0.59220 | 0.44400 | 0.38260 | 0.84720 | 0.86040 | 0.915500 | -0.04674 | 1.8110 | 1.43200 | 0.2868 | 0.30950 | -0.13690 | -1.3940000 | NA | -0.94240 | -0.01876 | 0.077300 | -1.01700 | -1.372000 | Her2 | NA | NA | T-DM1 + Pertuzumab | 0 | 1 | 1 | 1 | 48 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 125418 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganetespib | NA | NA | Ganetespib | 0 | 1 | 0 | 0 | 0 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune-/DRD.v3- | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/BP_Luminal/Immune- | HER2-/BP_Luminal/Immune- | HER2=0 | HR+/HER2=0 | HER2=0/BP_Luminal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0/Immune-/DRD.v3- | HER2=0/Immune-/DRD.v3- | -1.09300 | -0.781700 | -0.48760 | -1.263000 | -0.745800 | 0.66220 | -0.940000 | 0.90980 | -1.72800 | -1.69800 | -0.73020 | -0.57590 | -0.93760 | -1.322000 | -0.60520 | -0.4129 | -0.34090 | NA | NA | NA | 0.6096000 | NA | 1.03100 | -0.18380 | -1.279000 | 0.64060 | 0.453100 | LumA | NA | NA | Paclitaxel + Ganetespib | 1 | 0 | 0 | 0 | 49 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 127675 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Neratinib | NA | NA | N | 0 | 0 | 0 | 0 | 1 | 1 | Basal-type | TN | TN/MP1 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.29300 | 0.828500 | 1.17000 | 1.745000 | 1.624000 | 0.97350 | 0.749700 | -0.11100 | 0.12930 | 0.55900 | 1.36100 | 1.04200 | 1.06200 | 1.089000 | 0.08196 | -0.5394 | -0.38720 | -0.4157 | -0.34910 | -0.13850 | -1.1260000 | -0.3617 | 0.01659 | 0.09648 | -1.786000 | -0.98080 | -1.320000 | Basal | IM | BLIA | Paclitaxel + Neratinib | 0 | 0 | 0 | 0 | 59 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 127791 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Pertuzumab + Trastuzumab | NA | NA | Pertuzumab | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.96240 | -1.167000 | -1.17000 | -1.429000 | -1.249000 | -0.87150 | -1.027000 | 1.07100 | -0.19110 | -0.35390 | -0.71900 | 0.18000 | 0.06864 | -0.548700 | 0.54290 | 1.1550 | 0.36820 | 0.8130 | 0.56430 | -0.76900 | -1.4000000 | NA | 0.73710 | 1.40700 | 1.543000 | 0.56470 | 0.973900 | Her2 | NA | NA | Paclitaxel + Pertuzumab + Trastuzumab | 1 | 1 | 0 | 0 | 44 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 128051 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 0 | 1 | 1 | 0 | 0 | 0 | Luminal-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-Luminal | HER2+/Luminal-type | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+ | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP_Luminal | HER2+/BP-Luminal | HER2+/BP-Luminal | -0.34930 | -0.172200 | -0.38640 | -0.372300 | -0.822200 | -0.10920 | -0.812100 | 0.54510 | 0.44580 | -0.15260 | -0.88760 | -1.47800 | -1.35700 | -0.565100 | 0.28400 | -0.5193 | 0.02209 | -0.2318 | -0.16740 | 0.72870 | 0.3469000 | NA | -0.17310 | 0.25870 | 1.562000 | 0.89070 | 0.861800 | LumB | NA | NA | T-DM1 + Pertuzumab | 1 | 1 | 0 | 0 | 56 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 128675 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel | NA | NA | Ctr | 1 | 1 | 0 | 1 | 0 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | HR+HER2-/BP_Basal/Immune- | NA | NA | NA | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR+/HER2=0/Immune- or HR+/HER2low/BP-Basal/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | -0.62740 | -0.351800 | -0.42330 | 0.274300 | -1.267000 | -0.03677 | -1.007000 | -0.66710 | 1.06900 | 0.92560 | 0.80980 | 1.71500 | 1.75200 | 0.504300 | 0.31440 | -0.5314 | -0.43710 | 0.8261 | 1.32400 | -0.88480 | -1.1300000 | NA | -0.31700 | -0.57750 | -1.632000 | -0.83470 | -1.198000 | Basal | NA | NA | Paclitaxel | 1 | 0 | 1 | 1 | 47 | White | Perimenopausal(6-12 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 129837 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 0 | 0 | 0 | 1 | 0 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune-/DRD.v3+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/BP_Basal/Immune- | TN/BP_Basal/Immune- | HER2=0 | HR-/HER2=0 | HER2=0/BP_Basal | HER2=0/Immune- or HER2low/BP-Basal/Immune- | HR-/(HER2=0.or.low)/Immune- | HER2=0.or.low/Immune-/DRD.v3+ | HER2=0.or.low/Immune-/DRD.v3+ | 0.18490 | 0.129000 | -0.23280 | -0.451700 | -0.509000 | -0.05867 | 0.347200 | -0.05933 | 0.18520 | 0.59490 | 0.86880 | 1.24000 | 1.24700 | 0.347700 | 1.07100 | -0.1700 | -0.51200 | -0.3427 | -0.37730 | 1.39500 | 0.4459000 | 0.1942 | -0.27040 | 0.18330 | -0.622500 | -0.97520 | -0.613900 | Basal | UNS | LAR | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 0 | 67 | White | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
| 129973 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Veliparib dihydrochloride + Carboplatinum | NA | NA | VC | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR-/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.97090 | 1.241000 | 1.36000 | 1.097000 | 2.024000 | 0.70750 | 0.982700 | -0.39490 | 0.04194 | 1.07300 | 0.91940 | 1.61200 | 1.69700 | 1.653000 | 0.25600 | -0.2885 | -0.19200 | -0.2391 | -0.26100 | -0.26380 | -0.8008000 | -0.3734 | -0.96000 | 0.57030 | -0.542900 | -1.14900 | -0.728100 | Basal | IM | BLIA | Paclitaxel + ABT 888 + Carboplatin | 0 | 0 | 1 | 1 | 35 | White | Premenopausal(< 6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 130580 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Ganitumab | NA | NA | Ganitumab | 1 | 0 | 0 | 1 | 1 | 1 | Basal-type | TN | TN/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | NA | NA | NA | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.40270 | 0.485400 | 0.30520 | 0.581100 | 0.640000 | 0.37530 | 0.135700 | -0.05388 | 0.57870 | 0.72430 | 1.33200 | 0.41440 | 0.54480 | 0.189300 | -0.06618 | -0.5936 | -0.25670 | NA | NA | NA | -0.1167000 | NA | -0.46390 | 0.69260 | -0.853700 | -0.90780 | -0.282100 | Basal | BL1 | MES | Paclitaxel + Ganitumab | 0 | 0 | 1 | 1 | 56 | White | Above categories not applicable AND Age > 50 | Not Hispanic or Latino |
| 130892 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 | NA | NA | MK2206 | 1 | 1 | 0 | 1 | 1 | 1 | Basal-type | HR+HER2- | HR+HER2-/MP2 | HER2-/Immune+ | HER2-/Basal-type | HER2-/BP_Basal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Basal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 0.01530 | 0.007158 | 0.41820 | 0.764500 | 1.249000 | -0.53860 | 0.188800 | -0.01742 | -0.53720 | 0.55540 | 0.45290 | 0.63570 | 0.69970 | 0.331200 | -1.00400 | -0.6338 | -0.59650 | -0.3888 | -0.32540 | 0.24290 | -0.4053000 | -0.6858 | -0.56700 | 0.78080 | 0.004152 | -0.88810 | -0.807900 | NA | NA | NA | Paclitaxel + MK-2206 | 1 | 0 | 1 | 1 | 50 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Not Hispanic or Latino |
| 131595 | F | NA | Breast | NA | Breast | NA | NR | NA | NR | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + Trebananib | NA | NA | AMG386 | 0 | 1 | 0 | 0 | 1 | 0 | Luminal-type | HR+HER2- | HR+HER2-/MP1 | HER2-/Immune+ | HER2-/Luminal-type | HER2-/BP_Luminal | HER2-/Immune+ | HER2-/Immune+ | HER2low | HR+/HER2low | HER2low/BP_Luminal | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | HER2=0.or.low/Immune+ | 1.55200 | 1.614000 | 1.13400 | 1.811000 | 1.674000 | 0.18230 | 0.439100 | 0.72770 | 0.97930 | -0.27480 | -0.38740 | -1.59200 | -1.48800 | 0.973700 | -0.14340 | -0.6297 | -0.89290 | -0.4776 | -0.34710 | 1.27500 | -0.4092000 | -0.9520 | -0.97060 | -0.01307 | 1.277000 | 0.88230 | 1.506000 | LumB | NA | NA | Paclitaxel + AMG 386 | 1 | 0 | 0 | 0 | 43 | White | Premenopausal(<6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement) | Hispanic or Latino |
| 131961 | F | NA | Breast | NA | Breast | NA | R | NA | R | targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Trastuzumab Emtansine + Pertuzumab | NA | NA | TDM1/P | 1 | 1 | 1 | 0 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP1 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -1.78200 | -1.909000 | -1.70800 | -1.331000 | 0.155800 | -1.03700 | -1.197000 | 0.10620 | -0.66920 | -0.22450 | -1.00800 | -0.61710 | -0.60850 | -1.644000 | 0.02262 | 2.2290 | 2.78800 | 0.3577 | 0.09546 | -0.94310 | 0.1774000 | NA | 1.63400 | -0.39150 | -0.294200 | 0.17690 | -0.359600 | Her2 | NA | NA | T-DM1 + Pertuzumab | 1 | 1 | 0 | 1 | 44 | White | NA | Not Hispanic or Latino |
| 132463 | F | NA | Breast | NA | Breast | NA | R | NA | R | chemo+targeted | NA | microarray | NA | NA | NA | NA | NA | None | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Paclitaxel + MK-2206 + Trastuzumab | NA | NA | MK2206 | 1 | 1 | 1 | 1 | 0 | 0 | HER2-type | HR+HER2+ | HR+HER2+/MP2 | HER2+/BP-HER2_or_Basal | HER2+/HER2-type | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+ | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP_Her2orBasal | HER2+/BP-HER2_or_Basal | HER2+/BP-HER2_or_Basal | -1.09800 | -0.864200 | -1.14100 | -1.170000 | -0.593800 | -0.88350 | -0.298300 | 0.01909 | 1.90000 | 0.86810 | -0.53630 | -0.22600 | 0.01065 | -1.591000 | 1.25400 | 1.8010 | 2.08100 | 0.5597 | 0.76560 | 0.99740 | -1.4020000 | 1.5150 | -1.87900 | 0.44650 | 0.052500 | -0.80940 | -0.366800 | Her2 | NA | NA | Paclitaxel + MK-2206 + Trastuzumab | 1 | 1 | 1 | 1 | 64 | Asian | Postmenopausal (prior bilateral ovariectomy OR > 12 months since LMP with no prior hysterectomy) | Not Hispanic or Latino |
Segmentation Overview
We evaluated segmentation consistency by verifying that each patient had four DCE-MRI segmentation masks—one per time point—for reliable Functional Tumor Volume (FTV) analysis. Most patients met this requirement; those with fewer were flagged for review.
DCE-MRI Segmentation
Each scan undergoes multiple segmentation steps:
1. Manual VOI (Volume of Interest): A rectangular
region around the enhancing tumor.
2. Background Masking: Removes noise and fat saturation
artifacts.
3. Percent Enhancement (PE) Threshold: Filters
non-enhancing tissue.
4. Connectivity Filter: Ensures 3D tumor voxel
connectivity.
5. OMIT Regions: Manual exclusion of non-tumor
areas.
Segmentation masks are stored as 2D DICOM images,
aligned with the original DCE-MRI scans.
📥 Download masks: UCSF Box
Segmentation Metadata
ISPY1: MRI Metadata
Stored in ispy1_dce_series_info.xlsx, this file contains
metadata for 221 patients, including:
- Patient ID and Time Points (T1–T4)
- MRI Series Description and Unique ID
- SER (Signal Enhancement Ratio) indicator
- OMIT region counts (non-tumor exclusion markers)
# Load ISPY1 segmentation metadata
ispy1_dce_series_info <- read_excel(
path = file.path(input_dir, "ispy1_dce_series_info.xlsx"),
sheet = "DCE Series, All 20160823"
)
# Display ISPY1 segmentation metadata
kable(head(ispy1_dce_series_info, 20), caption = "DCE MRI Series Information") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| PATIENT_ID | SUBJECT_NO | TIME_POINT | VISIT | SERIES_DESC | SERIES_ID | SERIES_TYPE | SERIES_CAT | STUDY_UID | SERIES_UID | SERIES_PATH | PRIMARY_AIM | GOOD_VOLSER | VOLSER | ACQ_POST_PHASES | PRE_PHASE_INDEX | EARLY_PHASE_INDEX | LATE_PHASE_INDEX | OMIT_ROI_COUNT | BACKGROUND_PCT | BACKGROUND_THRESHOLD | PE_THRESHOLD | MIN_NEIGHBOR_COUNT | EARLY_DELAY | LATE_DELAY | VOI_CENTER_RL | VOI_CENTER_AP | VOI_CENTER_SI | VOI_HALF_WIDTH_RL | VOI_HALF_WIDTH_AP | VOI_HALF_WIDTH_SI | VOI_HALF_LENGTH_RL | VOI_HALF_LENGTH_AP | VOI_HALF_LENGTH_SI | VOI_HALF_DEPTH_RL | VOI_HALF_DEPTH_AP | VOI_HALF_DEPTH_SI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ISPY1_1001 | 1001 | T1 | 10 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.162588073261248159118785473116 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.334491271566855314830260417024 | ISPY1/ISPY1_1001/1.3.6.1.4.1.14519.5.2.1.7695.1700.162588073261248159118785473116/1.3.6.1.4.1.14519.5.2.1.7695.1700.334491271566855314830260417024 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | 57 | 70 | 4 | 142.908 | 471.909 | 82.89999 | -44.875000 | -12.7500000 | 0 | 39.84375 | 0 | 0 | 0 | 40.62500 | 34.000 | 0 | 0 |
| ISPY1_1001 | 1001 | T2 | 20 | Dynamic-3dfgre | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.251725059071532256976802593346 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.284567351304426376226790714264 | ISPY1/ISPY1_1001/1.3.6.1.4.1.14519.5.2.1.7695.1700.251725059071532256976802593346/1.3.6.1.4.1.14519.5.2.1.7695.1700.284567351304426376226790714264 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | 50 | 70 | 9 | 142.908 | 504.909 | 102.00000 | -46.503125 | -45.1562500 | 0 | 44.92188 | 0 | 0 | 0 | 36.71875 | 38.000 | 0 | 0 |
| ISPY1_1001 | 1001 | T3 | 30 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.186130315530827043916665138479 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.229054711046553504545787083659 | ISPY1/ISPY1_1001/1.3.6.1.4.1.14519.5.2.1.7695.1700.186130315530827043916665138479/1.3.6.1.4.1.14519.5.2.1.7695.1700.229054711046553504545787083659 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 4 | 142.908 | 467.909 | 75.80000 | -35.546875 | 14.2031250 | 0 | 43.35938 | 0 | 0 | 0 | 41.01562 | 30.000 | 0 | 0 |
| ISPY1_1001 | 1001 | T4 | 40 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.118757564401397374205631727107 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.195983148423034180376334647727 | ISPY1/ISPY1_1001/1.3.6.1.4.1.14519.5.2.1.7695.1700.118757564401397374205631727107/1.3.6.1.4.1.14519.5.2.1.7695.1700.195983148423034180376334647727 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 9 | 142.908 | 469.909 | 68.70000 | -47.659374 | 9.1562500 | 0 | 37.10938 | 0 | 0 | 0 | 31.25000 | 34.000 | 0 | 0 |
| ISPY1_1002 | 1002 | T1 | 10 | Dynamic-3dfgre | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.134976640792500085117907460097 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.200978610610642152304681086604 | ISPY1/ISPY1_1002/1.3.6.1.4.1.14519.5.2.1.7695.1700.134976640792500085117907460097/1.3.6.1.4.1.14519.5.2.1.7695.1700.200978610610642152304681086604 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | 47 | 70 | 4 | 142.908 | 487.909 | -120.10000 | -8.543750 | 2.0156250 | 0 | 24.21875 | 0 | 0 | 0 | 24.60938 | 21.000 | 0 | 0 |
| ISPY1_1002 | 1002 | T2 | 20 | Dynamic-3dfgre | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.213299857546682356325308543300 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.217629313261264666455404162928 | ISPY1/ISPY1_1002/1.3.6.1.4.1.14519.5.2.1.7695.1700.213299857546682356325308543300/1.3.6.1.4.1.14519.5.2.1.7695.1700.217629313261264666455404162928 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | 49 | 70 | 4 | 142.908 | 455.909 | -108.60000 | -15.184375 | 17.8125000 | 0 | 18.35938 | 0 | 0 | 0 | 17.96875 | 18.000 | 0 | 0 |
| ISPY1_1002 | 1002 | T3 | 30 | Dynamic-3dfgre | 5 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.310641334810324025592282005680 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.308304415889255945632238319959 | ISPY1/ISPY1_1002/1.3.6.1.4.1.14519.5.2.1.7695.1700.310641334810324025592282005680/1.3.6.1.4.1.14519.5.2.1.7695.1700.308304415889255945632238319959 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 4 | 142.908 | 480.909 | -124.50000 | -9.768749 | -0.5000000 | 0 | 12.50000 | 0 | 0 | 0 | 14.06250 | 18.000 | 0 | 0 |
| ISPY1_1002 | 1002 | T4 | 40 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.161260768808765067428187568337 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.123719184220486274456682769238 | ISPY1/ISPY1_1002/1.3.6.1.4.1.14519.5.2.1.7695.1700.161260768808765067428187568337/1.3.6.1.4.1.14519.5.2.1.7695.1700.123719184220486274456682769238 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 4 | 142.908 | 464.909 | -107.00000 | -10.784375 | -13.3906250 | 0 | 18.35938 | 0 | 0 | 0 | 18.35938 | 22.000 | 0 | 0 |
| ISPY1_1003 | 1003 | T1 | 10 | Dynamic-3dfgre | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.298080081174310898419212435677 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.217966338988546791542147267475 | ISPY1/ISPY1_1003/1.3.6.1.4.1.14519.5.2.1.7695.1700.298080081174310898419212435677/1.3.6.1.4.1.14519.5.2.1.7695.1700.217966338988546791542147267475 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | 41 | 70 | 4 | 142.908 | 464.909 | 80.00000 | -42.150000 | -38.9531250 | 0 | 39.84375 | 0 | 0 | 0 | 29.29688 | 23.000 | 0 | 0 |
| ISPY1_1003 | 1003 | T2 | 20 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.138213557573473307011258165864 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.299956820661297346246226539430 | ISPY1/ISPY1_1003/1.3.6.1.4.1.14519.5.2.1.7695.1700.138213557573473307011258165864/1.3.6.1.4.1.14519.5.2.1.7695.1700.299956820661297346246226539430 | 1 | 1 | yes | 2 | 0 | 1 | 2 | 1 | 60 | 49 | 70 | 4 | 142.908 | 448.909 | 85.89999 | -20.403125 | 23.5281260 | 0 | 33.98438 | 0 | 0 | 0 | 22.26562 | 18.000 | 0 | 0 |
| ISPY1_1003 | 1003 | T3 | 30 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.266827030532815128632203224043 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.160218149129103458523671303946 | ISPY1/ISPY1_1003/1.3.6.1.4.1.14519.5.2.1.7695.1700.266827030532815128632203224043/1.3.6.1.4.1.14519.5.2.1.7695.1700.160218149129103458523671303946 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 4 | 142.908 | 467.909 | 84.89999 | -31.143750 | -10.5156250 | 0 | 30.46875 | 0 | 0 | 0 | 19.92188 | 15.000 | 0 | 0 |
| ISPY1_1003 | 1003 | T4 | 40 | Dynamic-3dfgre | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.268904421322788588680650702521 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.333833341467598933118786229456 | ISPY1/ISPY1_1003/1.3.6.1.4.1.14519.5.2.1.7695.1700.268904421322788588680650702521/1.3.6.1.4.1.14519.5.2.1.7695.1700.333833341467598933118786229456 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 60 | NA | 70 | 9 | 142.908 | 477.909 | 82.40000 | -33.162500 | -23.6875000 | 0 | 26.56250 | 0 | 0 | 0 | 17.96875 | 14.000 | 0 | 0 |
| ISPY1_1004 | 1004 | T1 | 10 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 2 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.123666578177897342122858721875 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.228597508795509915957044689330 | ISPY1/ISPY1_1004/1.3.6.1.4.1.14519.5.2.1.7695.1700.123666578177897342122858721875/1.3.6.1.4.1.14519.5.2.1.7695.1700.228597508795509915957044689330 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | 72 | 90 | 13 | 204.500 | 613.500 | 78.75000 | -43.484375 | 19.2500000 | 0 | 36.91406 | 0 | 0 | 0 | 62.92969 | 34.500 | 0 | 0 |
| ISPY1_1004 | 1004 | T2 | 20 | PELVIC,Sag,3D,SPGR,VBw, GRx, | 2 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.139210337184334513376946376405 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.300426672774245107955438830162 | ISPY1/ISPY1_1004/1.3.6.1.4.1.14519.5.2.1.7695.1700.139210337184334513376946376405/1.3.6.1.4.1.14519.5.2.1.7695.1700.300426672774245107955438830162 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | 90 | 90 | 13 | 182.000 | 546.000 | 77.55000 | -36.514069 | 1.5781250 | 0 | 35.85938 | 0 | 0 | 0 | 53.78906 | 36.000 | 0 | 0 |
| ISPY1_1004 | 1004 | T3 | 30 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.472960478717934840128915797201 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.304375489738621951636388985164 | ISPY1/ISPY1_1004/1.3.6.1.4.1.14519.5.2.1.7695.1700.472960478717934840128915797201/1.3.6.1.4.1.14519.5.2.1.7695.1700.304375489738621951636388985164 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | NA | 90 | 13 | 186.500 | 559.500 | 70.89999 | -39.962502 | 3.0312500 | 0 | 45.35156 | 0 | 0 | 0 | 62.22656 | 47.000 | 0 | 0 |
| ISPY1_1004 | 1004 | T4 | 40 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 3 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.293613141232081657976654600946 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.794231212227579946078491333086 | ISPY1/ISPY1_1004/1.3.6.1.4.1.14519.5.2.1.7695.1700.293613141232081657976654600946/1.3.6.1.4.1.14519.5.2.1.7695.1700.794231212227579946078491333086 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | NA | 90 | 13 | 200.000 | 600.000 | 76.90000 | -27.107811 | 5.4453125 | 0 | 18.98438 | 0 | 0 | 0 | 45.00000 | 21.750 | 0 | 0 |
| ISPY1_1005 | 1005 | T1 | 10 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 2 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.168682333761219918185990956754 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.112512091674522544167508033512 | ISPY1/ISPY1_1005/1.3.6.1.4.1.14519.5.2.1.7695.1700.168682333761219918185990956754/1.3.6.1.4.1.14519.5.2.1.7695.1700.112512091674522544167508033512 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | 73 | 90 | 13 | 175.500 | 526.500 | 79.90001 | -41.065628 | 39.2656250 | 0 | 46.05469 | 0 | 0 | 0 | 45.35156 | 41.400 | 0 | 0 |
| ISPY1_1005 | 1005 | T2 | 20 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 2 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.175394084652801531467726863292 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.229410656917615455958078148940 | ISPY1/ISPY1_1005/1.3.6.1.4.1.14519.5.2.1.7695.1700.175394084652801531467726863292/1.3.6.1.4.1.14519.5.2.1.7695.1700.229410656917615455958078148940 | 0 | 0 | no | 1 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| ISPY1_1005 | 1005 | T3 | 30 | CTLMID,Sag,3D,SPGR,VBw, GRx, | 4 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.278680050483471060479946922896 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.253971398051889701206388702985 | ISPY1/ISPY1_1005/1.3.6.1.4.1.14519.5.2.1.7695.1700.278680050483471060479946922896/1.3.6.1.4.1.14519.5.2.1.7695.1700.253971398051889701206388702985 | 0 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | 70 | 90 | 13 | 206.500 | 619.500 | 72.40313 | -48.245316 | -0.1796875 | 0 | 46.05469 | 0 | 0 | 0 | 45.35156 | 38.825 | 0 | 0 |
| ISPY1_1005 | 1005 | T4 | 40 | 3D | 5 | dce/post | dce pre post | 1.3.6.1.4.1.14519.5.2.1.7695.1700.315178405770722394134357255715 | 1.3.6.1.4.1.14519.5.2.1.7695.1700.244038849484388506230960714412 | ISPY1/ISPY1_1005/1.3.6.1.4.1.14519.5.2.1.7695.1700.315178405770722394134357255715/1.3.6.1.4.1.14519.5.2.1.7695.1700.244038849484388506230960714412 | 1 | 1 | yes | 2 | 0 | 1 | 2 | NA | 65 | NA | 90 | 13 | 146.369 | 621.369 | 86.80000 | -37.195313 | 31.5546880 | 0 | 39.02344 | 0 | 0 | 0 | 41.83594 | 36.750 | 0 | 0 |
ISPY2: MRI Metadata
Metadata for ISPY2 was extracted from
series-data1741883133411.csv, containing records for
719 patients. This dataset includes MRI series-level
information for each patient, including:
- Subject ID
- Study Description (e.g.,
"ISPY2_MRI_T0") - Number of Images
- Modality (e.g.,
"MR","SEG")
# Load ISPY2 segmentation metadata
ispy2_dce_series_info <- read.csv(file.path(input_dir, "series-data1741883133411.csv"))
# Rename the "ispy2_dce_series_info" column to "PATIENT_ID"
colnames(ispy2_dce_series_info)[colnames(ispy2_dce_series_info) == "Subject.ID" ] <- "PATIENT_ID"
# Extract time points from the "Study.Description" column
ispy2_dce_series_info$TIME_POINT <- gsub(".*(T[0-9]+).*", "\\1", ispy2_dce_series_info$Study.Description)
# Display ISPY2 segmentation metadata
kable(head(ispy2_dce_series_info, 20), caption = "ISPY2 DCE MRI Series Information") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| PATIENT_ID | Study.UID | Study.Description | Study.Date | Series.ID | Series.Description | Number.of.images | File.Size..Bytes. | Collection.Name | Modality | Manufacturer | X3rd.Party.Analysis | Data.Description.URI | Series.Number | License.Name | License.URL | Date.Released | Series.Date | Protocol.Name | Body.Part.Examined | Annotations.Flag | Manufacturer.Model.Name | Software.Versions | TimeStamp | TIME_POINT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.313330782407390298344661311370946136238 | ISPY2: SCOUT ISPY2 | 51 | 6827686 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 1 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.279614487823636499235940907104792611414 | ISPY2: WATER:IDEAL | 45 | 23737674 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 3 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.2647355698869417812524932280893489028 | ISPY2: FAT:IDEAL | 45 | 23737582 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 300 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.206199927301215764245278347773827952523 | ISPY2: AX VIBRANT-SERIES | 106 | 55919746 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 500 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.266124567498488197926988477469957203969 | ISPY2: Ph1/AX VIBRANT-SERIES | 106 | 55924242 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 501 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.16099171300378572953268398707957231139 | ISPY2: Ph2/AX VIBRANT-SERIES | 106 | 55925922 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 502 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.121895725493536428267661368492699481578 | ISPY2: Ph3/AX VIBRANT-SERIES | 106 | 55926114 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 503 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.308685298008010400893831782399676642910 | ISPY2: Ph4/AX VIBRANT-SERIES | 106 | 55926134 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 504 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.279756085626113072659714263260085690790 | ISPY2: Ph5/AX VIBRANT-SERIES | 106 | 55926134 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 505 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.26092330643949841378637650049345388223 | ISPY2: Ph6/AX VIBRANT-SERIES | 106 | 55925942 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 506 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.269426242885278506123547184297304481837 | ISPY2: Ph7/AX VIBRANT-SERIES | 106 | 55926102 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 507 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.293975225635615618905200212057567133995 | ISPY2: VOLSER: uni-lateral cropped: SER | 80 | 10996402 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 51000 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 2022-05-02 00:00:00.0 | T0 | ||
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.192674667601251977965157561923468814958 | ISPY2: VOLSER: uni-lateral cropped: PE2 | 80 | 10919044 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 51002 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 2022-05-02 00:00:00.0 | T0 | ||
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.12678479245503031715538181201834554397 | ISPY2: VOLSER: uni-lateral cropped: PE5 | 80 | 10918864 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 51005 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 2022-05-02 00:00:00.0 | T0 | ||
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.89750556793240490681454008016631530523 | ISPY2: VOLSER: uni-lateral cropped: original DCE | 640 | 86184586 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 51800 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-10-26 | NA | NA | Signa HDxt | 2022-05-02 00:00:00.0 | T0 | ||
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.191407311082200176460176232508943888595 | ISPY2_MRI_T0 | 2002-10-26 | 1.3.6.1.4.1.14519.5.2.1.170670992519727173038447879955287778091 | ISPY2: VOLSER: uni-lateral cropped: Analysis Mask | 1 | 5285900 | ISPY2 | SEG | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 51900 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | NA | BREAST | NA | Signa HDxt | 220 | 2022-05-02 00:00:00.0 | T0 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.313717101780375925531007251690743209330 | ISPY2_MRI_T1 | 2002-11-29 | 1.3.6.1.4.1.14519.5.2.1.92528379925157023915586133268003573401 | ISPY2: SCOUT ISPY2 | 51 | 6827804 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 1 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-11-29 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T1 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.313717101780375925531007251690743209330 | ISPY2_MRI_T1 | 2002-11-29 | 1.3.6.1.4.1.14519.5.2.1.238689391857387503989892745238508896359 | ISPY2: WATER:IDEAL | 45 | 23737864 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 3 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-11-29 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T1 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.313717101780375925531007251690743209330 | ISPY2_MRI_T1 | 2002-11-29 | 1.3.6.1.4.1.14519.5.2.1.91162948756112161226686952449027586143 | ISPY2: FAT:IDEAL | 45 | 23737796 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 300 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-11-29 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T1 | |
| ISPY2-100899 | 1.3.6.1.4.1.14519.5.2.1.313717101780375925531007251690743209330 | ISPY2_MRI_T1 | 2002-11-29 | 1.3.6.1.4.1.14519.5.2.1.145698408400144867676386090516002449032 | ISPY2: AX VIBRANT-SERIES | 100 | 52767818 | ISPY2 | MR | GE MEDICAL SYSTEMS | NO | https://doi.org/10.7937/TCIA.D8Z0-9T85 | 600 | Creative Commons Attribution 4.0 International License | https://creativecommons.org/licenses/by/4.0/ | 2022-05-02 | 2002-11-29 | NA | NA | Signa HDxt | 24 | 2022-05-02 00:00:00.0 | T1 |
# Select only PATIENT_ID and TIME_POINT columns from both datasets
ispy1_selected <- ispy1_dce_series_info[, c("PATIENT_ID", "TIME_POINT")]
ispy2_selected <- ispy2_dce_series_info[, c("PATIENT_ID", "TIME_POINT")]
# Merge based on PATIENT_ID and TIME_POINT
ispy1and2 <- merge(ispy1_selected, ispy2_selected, by = c("PATIENT_ID", "TIME_POINT"), all = TRUE)Segmentation Completeness Check (T1–T4)
Each of the 940 patients is expected to have at least four segmentation masks, one for each of their four MRI scans
# Count segmentations per patient for each time point
series_per_patient <- ispy1and2 %>%
group_by(PATIENT_ID, TIME_POINT) %>%
summarize(Series_Count = n(), .groups = 'drop') %>%
pivot_wider(names_from = TIME_POINT, values_from = Series_Count, values_fill = 0) %>%
mutate(across(starts_with("T"), as.numeric),
Total_Segmentations = rowSums(select(., starts_with("T")), na.rm = TRUE))
# Display segmentation counts per patient
kable(series_per_patient, caption = "Segmentation Counts per Patient") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| PATIENT_ID | T1 | T2 | T3 | T4 | T0 | Total_Segmentations |
|---|---|---|---|---|---|---|
| ISPY1_1001 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1002 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1003 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1004 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1005 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1007 | 3 | 6 | 0 | 3 | 0 | 12 |
| ISPY1_1008 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1009 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1010 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1011 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1012 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1013 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1015 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1016 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1017 | 1 | 0 | 1 | 1 | 0 | 3 |
| ISPY1_1019 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1021 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1022 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1024 | 0 | 0 | 0 | 3 | 0 | 3 |
| ISPY1_1025 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1026 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1027 | 1 | 0 | 0 | 0 | 0 | 1 |
| ISPY1_1028 | 0 | 0 | 3 | 0 | 0 | 3 |
| ISPY1_1029 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1030 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1031 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1032 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1033 | 0 | 0 | 0 | 3 | 0 | 3 |
| ISPY1_1034 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1035 | 4 | 4 | 3 | 0 | 0 | 11 |
| ISPY1_1036 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1037 | 1 | 1 | 2 | 1 | 0 | 5 |
| ISPY1_1038 | 2 | 1 | 2 | 1 | 0 | 6 |
| ISPY1_1039 | 0 | 3 | 3 | 3 | 0 | 9 |
| ISPY1_1040 | 3 | 0 | 0 | 0 | 0 | 3 |
| ISPY1_1041 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1042 | 4 | 3 | 3 | 3 | 0 | 13 |
| ISPY1_1043 | 0 | 3 | 3 | 3 | 0 | 9 |
| ISPY1_1044 | 0 | 0 | 0 | 1 | 0 | 1 |
| ISPY1_1045 | 4 | 4 | 4 | 0 | 0 | 12 |
| ISPY1_1046 | 0 | 3 | 0 | 3 | 0 | 6 |
| ISPY1_1047 | 4 | 3 | 4 | 3 | 0 | 14 |
| ISPY1_1048 | 0 | 3 | 0 | 0 | 0 | 3 |
| ISPY1_1049 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1050 | 1 | 0 | 0 | 0 | 0 | 1 |
| ISPY1_1051 | 1 | 0 | 1 | 1 | 0 | 3 |
| ISPY1_1053 | 3 | 3 | 0 | 3 | 0 | 9 |
| ISPY1_1054 | 1 | 2 | 1 | 1 | 0 | 5 |
| ISPY1_1055 | 3 | 4 | 4 | 4 | 0 | 15 |
| ISPY1_1056 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1057 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1058 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1059 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1060 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1061 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1062 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1063 | 0 | 4 | 4 | 4 | 0 | 12 |
| ISPY1_1064 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1065 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1066 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1067 | 2 | 1 | 1 | 0 | 0 | 4 |
| ISPY1_1068 | 3 | 1 | 3 | 0 | 0 | 7 |
| ISPY1_1069 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1070 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1071 | 0 | 3 | 3 | 3 | 0 | 9 |
| ISPY1_1072 | 3 | 0 | 3 | 3 | 0 | 9 |
| ISPY1_1073 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1074 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1075 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1077 | 1 | 1 | 3 | 1 | 0 | 6 |
| ISPY1_1078 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1079 | 3 | 3 | 0 | 0 | 0 | 6 |
| ISPY1_1081 | 4 | 6 | 0 | 0 | 0 | 10 |
| ISPY1_1082 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1083 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1084 | 4 | 3 | 0 | 3 | 0 | 10 |
| ISPY1_1085 | 3 | 3 | 4 | 4 | 0 | 14 |
| ISPY1_1086 | 3 | 0 | 0 | 3 | 0 | 6 |
| ISPY1_1087 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1088 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1089 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1090 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1091 | 3 | 3 | 0 | 4 | 0 | 10 |
| ISPY1_1092 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1093 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1094 | 1 | 0 | 1 | 1 | 0 | 3 |
| ISPY1_1095 | 0 | 0 | 0 | 3 | 0 | 3 |
| ISPY1_1096 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1097 | 3 | 4 | 3 | 4 | 0 | 14 |
| ISPY1_1098 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1099 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1100 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1101 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1102 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1103 | 3 | 1 | 3 | 3 | 0 | 10 |
| ISPY1_1104 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1106 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1107 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1109 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1110 | 0 | 0 | 3 | 4 | 0 | 7 |
| ISPY1_1111 | 0 | 3 | 3 | 4 | 0 | 10 |
| ISPY1_1112 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1113 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1114 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1115 | 1 | 3 | 3 | 3 | 0 | 10 |
| ISPY1_1116 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1117 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1118 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1120 | 1 | 1 | 1 | 0 | 0 | 3 |
| ISPY1_1121 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1122 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1123 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1124 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1125 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1126 | 3 | 3 | 0 | 4 | 0 | 10 |
| ISPY1_1127 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1128 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1129 | 3 | 3 | 4 | 4 | 0 | 14 |
| ISPY1_1130 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1132 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1134 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1135 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1136 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1137 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1138 | 0 | 1 | 1 | 1 | 0 | 3 |
| ISPY1_1139 | 3 | 4 | 3 | 3 | 0 | 13 |
| ISPY1_1140 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1141 | 3 | 4 | 3 | 3 | 0 | 13 |
| ISPY1_1142 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1143 | 4 | 4 | 4 | 4 | 0 | 16 |
| ISPY1_1144 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1145 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1146 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1147 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1148 | 4 | 1 | 3 | 3 | 0 | 11 |
| ISPY1_1149 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1150 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1151 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1152 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1154 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1155 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1156 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1157 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1158 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1159 | 3 | 3 | 4 | 3 | 0 | 13 |
| ISPY1_1160 | 4 | 4 | 0 | 5 | 0 | 13 |
| ISPY1_1161 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1162 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1163 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1164 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1165 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1166 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1167 | 4 | 3 | 6 | 3 | 0 | 16 |
| ISPY1_1168 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1169 | 3 | 4 | 3 | 3 | 0 | 13 |
| ISPY1_1170 | 3 | 4 | 4 | 4 | 0 | 15 |
| ISPY1_1171 | 1 | 3 | 1 | 1 | 0 | 6 |
| ISPY1_1172 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1173 | 4 | 0 | 3 | 4 | 0 | 11 |
| ISPY1_1174 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1175 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1176 | 1 | 1 | 0 | 0 | 0 | 2 |
| ISPY1_1177 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1179 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1180 | 4 | 3 | 3 | 2 | 0 | 12 |
| ISPY1_1181 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1182 | 6 | 6 | 6 | 6 | 0 | 24 |
| ISPY1_1183 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1184 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1185 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1187 | 3 | 3 | 3 | 0 | 0 | 9 |
| ISPY1_1188 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1189 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1191 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1192 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1193 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1194 | 1 | 3 | 1 | 1 | 0 | 6 |
| ISPY1_1196 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1197 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1198 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1199 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1200 | 6 | 0 | 3 | 3 | 0 | 12 |
| ISPY1_1201 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1202 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1203 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1204 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1205 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1206 | 3 | 7 | 3 | 6 | 0 | 19 |
| ISPY1_1207 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1208 | 3 | 3 | 0 | 3 | 0 | 9 |
| ISPY1_1209 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1210 | 3 | 3 | 3 | 0 | 0 | 9 |
| ISPY1_1211 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1212 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1213 | 5 | 0 | 0 | 6 | 0 | 11 |
| ISPY1_1214 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1215 | 1 | 0 | 0 | 0 | 0 | 1 |
| ISPY1_1216 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1217 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1218 | 3 | 4 | 3 | 3 | 0 | 13 |
| ISPY1_1219 | 3 | 3 | 3 | 0 | 0 | 9 |
| ISPY1_1220 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1221 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1222 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1223 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1224 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1225 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1226 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1227 | 1 | 1 | 0 | 1 | 0 | 3 |
| ISPY1_1228 | 3 | 3 | 3 | 6 | 0 | 15 |
| ISPY1_1229 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1230 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1231 | 1 | 0 | 1 | 1 | 0 | 3 |
| ISPY1_1232 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1233 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1234 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY1_1235 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1236 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1237 | 3 | 3 | 3 | 3 | 0 | 12 |
| ISPY1_1238 | 3 | 3 | 0 | 0 | 0 | 6 |
| ISPY1_1239 | 1 | 1 | 1 | 1 | 0 | 4 |
| ISPY2-100899 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-102011 | 9 | 10 | 9 | 0 | 11 | 39 |
| ISPY2-103693 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-104384 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-105286 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-105513 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-108939 | 12 | 0 | 0 | 0 | 12 | 24 |
| ISPY2-109623 | 10 | 11 | 17 | 0 | 10 | 48 |
| ISPY2-109874 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-109980 | 9 | 0 | 9 | 0 | 9 | 27 |
| ISPY2-111004 | 18 | 22 | 18 | 0 | 18 | 76 |
| ISPY2-111038 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-111344 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-111646 | 17 | 16 | 0 | 0 | 18 | 51 |
| ISPY2-111674 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-111881 | 13 | 14 | 13 | 0 | 13 | 53 |
| ISPY2-112606 | 14 | 14 | 13 | 0 | 14 | 55 |
| ISPY2-114087 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-115638 | 14 | 13 | 13 | 0 | 14 | 54 |
| ISPY2-116165 | 0 | 0 | 0 | 0 | 9 | 9 |
| ISPY2-117424 | 13 | 12 | 12 | 0 | 12 | 49 |
| ISPY2-117707 | 15 | 15 | 14 | 0 | 15 | 59 |
| ISPY2-119928 | 13 | 13 | 0 | 0 | 13 | 39 |
| ISPY2-120001 | 8 | 7 | 9 | 0 | 8 | 32 |
| ISPY2-120422 | 13 | 13 | 0 | 0 | 14 | 40 |
| ISPY2-122287 | 8 | 8 | 0 | 0 | 8 | 24 |
| ISPY2-122579 | 15 | 14 | 14 | 0 | 14 | 57 |
| ISPY2-122795 | 9 | 13 | 0 | 0 | 13 | 35 |
| ISPY2-123660 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-125130 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-125418 | 13 | 13 | 0 | 0 | 13 | 39 |
| ISPY2-127675 | 13 | 14 | 12 | 0 | 13 | 52 |
| ISPY2-127791 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-128051 | 8 | 8 | 7 | 0 | 8 | 31 |
| ISPY2-128675 | 9 | 10 | 9 | 0 | 9 | 37 |
| ISPY2-129837 | 12 | 12 | 12 | 0 | 12 | 48 |
| ISPY2-129973 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-130892 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-131595 | 15 | 16 | 0 | 0 | 15 | 46 |
| ISPY2-132463 | 12 | 12 | 13 | 0 | 12 | 49 |
| ISPY2-133650 | 9 | 8 | 0 | 0 | 8 | 25 |
| ISPY2-134526 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-136536 | 8 | 8 | 7 | 0 | 7 | 30 |
| ISPY2-138425 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-139137 | 9 | 8 | 9 | 0 | 8 | 34 |
| ISPY2-139771 | 10 | 0 | 8 | 0 | 10 | 28 |
| ISPY2-141782 | 13 | 14 | 14 | 0 | 13 | 54 |
| ISPY2-142688 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-145513 | 14 | 14 | 13 | 0 | 14 | 55 |
| ISPY2-146033 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-147139 | 14 | 14 | 15 | 0 | 14 | 57 |
| ISPY2-149654 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-151230 | 0 | 14 | 14 | 0 | 14 | 42 |
| ISPY2-151481 | 7 | 7 | 12 | 0 | 7 | 33 |
| ISPY2-151980 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-152197 | 16 | 0 | 16 | 0 | 16 | 48 |
| ISPY2-153327 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-153880 | 15 | 9 | 15 | 0 | 11 | 50 |
| ISPY2-154293 | 16 | 16 | 16 | 0 | 9 | 57 |
| ISPY2-155171 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-157270 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-157463 | 14 | 8 | 8 | 0 | 8 | 38 |
| ISPY2-159284 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-159352 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-160120 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-164468 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-166412 | 12 | 12 | 13 | 0 | 12 | 49 |
| ISPY2-166782 | 0 | 0 | 7 | 0 | 7 | 14 |
| ISPY2-167271 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-168044 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-169536 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-172168 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-172283 | 15 | 14 | 15 | 0 | 15 | 59 |
| ISPY2-174903 | 9 | 16 | 16 | 0 | 9 | 50 |
| ISPY2-174904 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-177795 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-178649 | 8 | 8 | 8 | 0 | 7 | 31 |
| ISPY2-178815 | 14 | 13 | 9 | 0 | 15 | 51 |
| ISPY2-180027 | 12 | 0 | 12 | 0 | 13 | 37 |
| ISPY2-180663 | 14 | 13 | 13 | 0 | 14 | 54 |
| ISPY2-181442 | 14 | 13 | 14 | 0 | 14 | 55 |
| ISPY2-181819 | 8 | 7 | 7 | 0 | 8 | 30 |
| ISPY2-182346 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-183831 | 12 | 12 | 13 | 0 | 12 | 49 |
| ISPY2-188091 | 0 | 0 | 0 | 0 | 14 | 14 |
| ISPY2-188511 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-190224 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-192548 | 14 | 14 | 0 | 0 | 14 | 42 |
| ISPY2-194024 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-196024 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-197942 | 14 | 14 | 15 | 0 | 14 | 57 |
| ISPY2-198891 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-199115 | 15 | 16 | 16 | 0 | 15 | 62 |
| ISPY2-199960 | 0 | 0 | 0 | 0 | 13 | 13 |
| ISPY2-200222 | 13 | 16 | 15 | 0 | 12 | 56 |
| ISPY2-201831 | 13 | 13 | 13 | 0 | 12 | 51 |
| ISPY2-201873 | 12 | 13 | 13 | 0 | 14 | 52 |
| ISPY2-202539 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-202956 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-203254 | 12 | 12 | 12 | 0 | 14 | 50 |
| ISPY2-204939 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-208265 | 12 | 7 | 12 | 0 | 7 | 38 |
| ISPY2-208303 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-209397 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-211408 | 12 | 12 | 12 | 0 | 13 | 49 |
| ISPY2-212307 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-213328 | 0 | 0 | 18 | 0 | 18 | 36 |
| ISPY2-213672 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-215932 | 12 | 13 | 13 | 0 | 13 | 51 |
| ISPY2-218249 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-220664 | 0 | 0 | 0 | 0 | 6 | 6 |
| ISPY2-221375 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-223030 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-223526 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-225836 | 13 | 9 | 14 | 0 | 14 | 50 |
| ISPY2-227832 | 15 | 13 | 13 | 0 | 13 | 54 |
| ISPY2-227881 | 8 | 8 | 17 | 0 | 10 | 43 |
| ISPY2-228192 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-228340 | 13 | 14 | 14 | 0 | 13 | 54 |
| ISPY2-229144 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-229328 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-229824 | 12 | 12 | 12 | 0 | 12 | 48 |
| ISPY2-231633 | 17 | 16 | 16 | 0 | 16 | 65 |
| ISPY2-233832 | 0 | 14 | 0 | 0 | 14 | 28 |
| ISPY2-233962 | 15 | 14 | 14 | 0 | 14 | 57 |
| ISPY2-234272 | 16 | 16 | 16 | 0 | 9 | 57 |
| ISPY2-235995 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-236470 | 13 | 0 | 0 | 0 | 13 | 26 |
| ISPY2-238790 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-239061 | 8 | 8 | 9 | 0 | 8 | 33 |
| ISPY2-240035 | 16 | 16 | 16 | 0 | 13 | 61 |
| ISPY2-240432 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-241705 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-242370 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-243836 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-245655 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-246134 | 8 | 9 | 0 | 0 | 8 | 25 |
| ISPY2-247641 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-248255 | 12 | 12 | 12 | 0 | 13 | 49 |
| ISPY2-250274 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-252748 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-254060 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-254273 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-255078 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-255535 | 8 | 7 | 7 | 0 | 8 | 30 |
| ISPY2-255577 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-257735 | 0 | 0 | 0 | 0 | 7 | 7 |
| ISPY2-259206 | 8 | 8 | 16 | 0 | 9 | 41 |
| ISPY2-259899 | 8 | 0 | 0 | 0 | 8 | 16 |
| ISPY2-261304 | 16 | 17 | 13 | 0 | 16 | 62 |
| ISPY2-262131 | 13 | 0 | 0 | 0 | 14 | 27 |
| ISPY2-264678 | 13 | 12 | 12 | 0 | 13 | 50 |
| ISPY2-266509 | 0 | 15 | 16 | 0 | 16 | 47 |
| ISPY2-267306 | 9 | 8 | 8 | 0 | 9 | 34 |
| ISPY2-268937 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-273691 | 9 | 10 | 17 | 0 | 10 | 46 |
| ISPY2-273745 | 9 | 8 | 8 | 0 | 8 | 33 |
| ISPY2-277848 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-279902 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-282082 | 14 | 14 | 14 | 0 | 13 | 55 |
| ISPY2-282644 | 0 | 0 | 0 | 0 | 8 | 8 |
| ISPY2-282777 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-284355 | 16 | 16 | 15 | 0 | 15 | 62 |
| ISPY2-286984 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-287300 | 15 | 10 | 8 | 0 | 14 | 47 |
| ISPY2-289107 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-290413 | 15 | 12 | 15 | 0 | 15 | 57 |
| ISPY2-291515 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-294176 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-294265 | 16 | 15 | 16 | 0 | 16 | 63 |
| ISPY2-299364 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-299840 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-300724 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-301289 | 15 | 0 | 0 | 0 | 15 | 30 |
| ISPY2-301968 | 14 | 0 | 0 | 0 | 13 | 27 |
| ISPY2-303685 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-303947 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-306127 | 0 | 0 | 0 | 0 | 12 | 12 |
| ISPY2-307659 | 8 | 8 | 8 | 0 | 9 | 33 |
| ISPY2-309830 | 13 | 0 | 0 | 0 | 13 | 26 |
| ISPY2-311316 | 15 | 15 | 15 | 0 | 14 | 59 |
| ISPY2-311455 | 19 | 18 | 19 | 0 | 18 | 74 |
| ISPY2-313243 | 8 | 7 | 7 | 0 | 8 | 30 |
| ISPY2-313672 | 9 | 0 | 9 | 0 | 9 | 27 |
| ISPY2-316996 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-317131 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-318293 | 7 | 7 | 8 | 0 | 8 | 30 |
| ISPY2-318407 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-318438 | 0 | 0 | 13 | 0 | 13 | 26 |
| ISPY2-318569 | 16 | 17 | 16 | 0 | 16 | 65 |
| ISPY2-319324 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-324021 | 7 | 7 | 8 | 0 | 8 | 30 |
| ISPY2-326202 | 14 | 13 | 14 | 0 | 15 | 56 |
| ISPY2-327133 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-327142 | 13 | 0 | 13 | 0 | 12 | 38 |
| ISPY2-327917 | 15 | 0 | 0 | 0 | 15 | 30 |
| ISPY2-329941 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-330134 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-331192 | 14 | 14 | 14 | 0 | 13 | 55 |
| ISPY2-332655 | 0 | 0 | 0 | 0 | 15 | 15 |
| ISPY2-333145 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-335091 | 8 | 7 | 9 | 0 | 8 | 32 |
| ISPY2-340186 | 12 | 13 | 12 | 0 | 14 | 51 |
| ISPY2-341238 | 15 | 15 | 14 | 0 | 15 | 59 |
| ISPY2-342142 | 9 | 9 | 9 | 0 | 8 | 35 |
| ISPY2-342996 | 10 | 17 | 17 | 0 | 10 | 54 |
| ISPY2-345460 | 0 | 0 | 0 | 0 | 8 | 8 |
| ISPY2-345483 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-345574 | 9 | 14 | 8 | 0 | 8 | 39 |
| ISPY2-347516 | 13 | 0 | 13 | 0 | 13 | 39 |
| ISPY2-348009 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-349225 | 16 | 16 | 0 | 0 | 16 | 48 |
| ISPY2-349330 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-349639 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-350331 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-353318 | 0 | 13 | 13 | 0 | 13 | 39 |
| ISPY2-355292 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-356399 | 13 | 14 | 14 | 0 | 14 | 55 |
| ISPY2-356684 | 13 | 13 | 14 | 0 | 13 | 53 |
| ISPY2-357017 | 7 | 7 | 8 | 0 | 8 | 30 |
| ISPY2-357034 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-360937 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-362993 | 12 | 12 | 12 | 0 | 12 | 48 |
| ISPY2-363669 | 15 | 16 | 17 | 0 | 15 | 63 |
| ISPY2-366120 | 15 | 15 | 0 | 0 | 15 | 45 |
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| ISPY2-800710 | 9 | 13 | 13 | 0 | 13 | 48 |
| ISPY2-802105 | 17 | 18 | 18 | 0 | 18 | 71 |
| ISPY2-802778 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-803514 | 13 | 12 | 12 | 0 | 13 | 50 |
| ISPY2-803677 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-804233 | 9 | 9 | 9 | 0 | 10 | 37 |
| ISPY2-808714 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-809037 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-809649 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-810965 | 10 | 17 | 17 | 0 | 10 | 54 |
| ISPY2-812089 | 7 | 8 | 8 | 0 | 8 | 31 |
| ISPY2-814299 | 0 | 8 | 14 | 0 | 14 | 36 |
| ISPY2-815421 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-815493 | 8 | 7 | 7 | 0 | 7 | 29 |
| ISPY2-819622 | 9 | 9 | 14 | 0 | 15 | 47 |
| ISPY2-820348 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-823618 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-824234 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-824350 | 13 | 13 | 0 | 0 | 13 | 39 |
| ISPY2-824512 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-825363 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-828199 | 14 | 0 | 0 | 0 | 14 | 28 |
| ISPY2-829491 | 13 | 11 | 13 | 0 | 14 | 51 |
| ISPY2-830486 | 8 | 0 | 0 | 0 | 8 | 16 |
| ISPY2-830958 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-831702 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-832056 | 13 | 14 | 14 | 0 | 15 | 56 |
| ISPY2-833536 | 12 | 13 | 14 | 0 | 14 | 53 |
| ISPY2-834418 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-835137 | 13 | 14 | 0 | 0 | 0 | 27 |
| ISPY2-835658 | 8 | 7 | 8 | 0 | 8 | 31 |
| ISPY2-836114 | 10 | 13 | 13 | 0 | 14 | 50 |
| ISPY2-836983 | 12 | 12 | 12 | 0 | 12 | 48 |
| ISPY2-840501 | 14 | 14 | 14 | 0 | 13 | 55 |
| ISPY2-841336 | 8 | 7 | 8 | 0 | 8 | 31 |
| ISPY2-845079 | 10 | 9 | 9 | 0 | 9 | 37 |
| ISPY2-845147 | 14 | 13 | 13 | 0 | 13 | 53 |
| ISPY2-845663 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-846156 | 13 | 0 | 13 | 0 | 14 | 40 |
| ISPY2-847272 | 9 | 9 | 0 | 0 | 9 | 27 |
| ISPY2-847753 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-848371 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-849605 | 14 | 0 | 13 | 0 | 13 | 40 |
| ISPY2-851180 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-851223 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-851488 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-857165 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-859699 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-862244 | 9 | 10 | 9 | 0 | 9 | 37 |
| ISPY2-865416 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-872188 | 14 | 0 | 15 | 0 | 16 | 45 |
| ISPY2-873686 | 8 | 8 | 7 | 0 | 8 | 31 |
| ISPY2-876511 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-877463 | 13 | 0 | 0 | 0 | 13 | 26 |
| ISPY2-882538 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-883696 | 15 | 15 | 16 | 0 | 16 | 62 |
| ISPY2-883886 | 13 | 13 | 13 | 0 | 14 | 53 |
| ISPY2-884266 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-885590 | 14 | 14 | 14 | 0 | 13 | 55 |
| ISPY2-885871 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-889049 | 13 | 13 | 12 | 0 | 13 | 51 |
| ISPY2-889225 | 12 | 13 | 0 | 0 | 12 | 37 |
| ISPY2-889721 | 15 | 15 | 15 | 0 | 15 | 60 |
| ISPY2-890414 | 13 | 13 | 12 | 0 | 13 | 51 |
| ISPY2-891645 | 13 | 12 | 13 | 0 | 13 | 51 |
| ISPY2-892390 | 14 | 14 | 14 | 0 | 13 | 55 |
| ISPY2-893874 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-894128 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-894491 | 18 | 14 | 14 | 0 | 18 | 64 |
| ISPY2-896621 | 13 | 0 | 14 | 0 | 13 | 40 |
| ISPY2-896939 | 13 | 15 | 15 | 0 | 14 | 57 |
| ISPY2-898618 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-899381 | 18 | 17 | 18 | 0 | 18 | 71 |
| ISPY2-903880 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-904269 | 14 | 9 | 9 | 0 | 14 | 46 |
| ISPY2-905264 | 8 | 7 | 8 | 0 | 8 | 31 |
| ISPY2-906042 | 8 | 8 | 9 | 0 | 9 | 34 |
| ISPY2-906795 | 8 | 8 | 0 | 0 | 9 | 25 |
| ISPY2-910188 | 13 | 13 | 13 | 0 | 14 | 53 |
| ISPY2-910706 | 15 | 14 | 14 | 0 | 15 | 58 |
| ISPY2-912836 | 10 | 10 | 17 | 0 | 10 | 47 |
| ISPY2-913225 | 9 | 14 | 14 | 0 | 9 | 46 |
| ISPY2-914968 | 8 | 9 | 8 | 0 | 8 | 33 |
| ISPY2-916586 | 0 | 0 | 0 | 0 | 13 | 13 |
| ISPY2-916645 | 14 | 13 | 13 | 0 | 14 | 54 |
| ISPY2-917762 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-918979 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-920479 | 14 | 14 | 14 | 0 | 12 | 54 |
| ISPY2-922872 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-923968 | 13 | 13 | 13 | 0 | 14 | 53 |
| ISPY2-924812 | 8 | 8 | 8 | 0 | 7 | 31 |
| ISPY2-924868 | 14 | 15 | 14 | 0 | 14 | 57 |
| ISPY2-924895 | 16 | 0 | 0 | 0 | 16 | 32 |
| ISPY2-925691 | 11 | 9 | 9 | 0 | 9 | 38 |
| ISPY2-930172 | 13 | 0 | 0 | 0 | 12 | 25 |
| ISPY2-930853 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-930903 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-932200 | 18 | 18 | 16 | 0 | 18 | 70 |
| ISPY2-934459 | 13 | 14 | 14 | 0 | 14 | 55 |
| ISPY2-934906 | 17 | 18 | 18 | 0 | 18 | 71 |
| ISPY2-935460 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-940186 | 17 | 17 | 18 | 0 | 10 | 62 |
| ISPY2-941191 | 12 | 12 | 13 | 0 | 12 | 49 |
| ISPY2-941926 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-943879 | 8 | 9 | 8 | 0 | 9 | 34 |
| ISPY2-944419 | 14 | 9 | 14 | 0 | 14 | 51 |
| ISPY2-944536 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-950131 | 18 | 18 | 18 | 0 | 18 | 72 |
| ISPY2-953262 | 14 | 14 | 14 | 0 | 14 | 56 |
| ISPY2-953885 | 14 | 14 | 15 | 0 | 15 | 58 |
| ISPY2-955953 | 13 | 13 | 12 | 0 | 13 | 51 |
| ISPY2-957408 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-959366 | 14 | 13 | 13 | 0 | 14 | 54 |
| ISPY2-960490 | 13 | 0 | 13 | 0 | 13 | 39 |
| ISPY2-960963 | 9 | 9 | 8 | 0 | 9 | 35 |
| ISPY2-962472 | 9 | 8 | 7 | 0 | 8 | 32 |
| ISPY2-962664 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-962827 | 12 | 12 | 13 | 0 | 12 | 49 |
| ISPY2-965265 | 7 | 0 | 7 | 0 | 7 | 21 |
| ISPY2-966016 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-972307 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-974181 | 14 | 13 | 13 | 0 | 14 | 54 |
| ISPY2-974618 | 7 | 7 | 7 | 0 | 7 | 28 |
| ISPY2-981461 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-981664 | 8 | 8 | 0 | 0 | 8 | 24 |
| ISPY2-982505 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-983841 | 14 | 13 | 13 | 0 | 13 | 53 |
| ISPY2-986734 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-987995 | 8 | 8 | 8 | 0 | 8 | 32 |
| ISPY2-988443 | 9 | 16 | 16 | 0 | 9 | 50 |
| ISPY2-988665 | 16 | 16 | 16 | 0 | 16 | 64 |
| ISPY2-990443 | 13 | 13 | 13 | 0 | 13 | 52 |
| ISPY2-994987 | 15 | 0 | 0 | 0 | 15 | 30 |
| ISPY2-997702 | 12 | 13 | 12 | 0 | 13 | 50 |
| ISPY2-999264 | 9 | 9 | 9 | 0 | 9 | 36 |
| ISPY2-999733 | 11 | 9 | 9 | 0 | 9 | 38 |
Patients missing one or more segmentation masks need further review (24 patients).
# Identify patients with <4 segmentations
patients_less_than_4 <- series_per_patient %>%
filter(Total_Segmentations < 4) %>%
select(PATIENT_ID, Total_Segmentations)
# Display patients missing segmentations
kable(patients_less_than_4, caption = "Patients with Less Than 4 Segmentation Masks") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| PATIENT_ID | Total_Segmentations |
|---|---|
| ISPY1_1017 | 3 |
| ISPY1_1022 | 3 |
| ISPY1_1024 | 3 |
| ISPY1_1027 | 1 |
| ISPY1_1028 | 3 |
| ISPY1_1033 | 3 |
| ISPY1_1036 | 3 |
| ISPY1_1040 | 3 |
| ISPY1_1044 | 1 |
| ISPY1_1048 | 3 |
| ISPY1_1050 | 1 |
| ISPY1_1051 | 3 |
| ISPY1_1087 | 3 |
| ISPY1_1094 | 3 |
| ISPY1_1095 | 3 |
| ISPY1_1101 | 3 |
| ISPY1_1120 | 3 |
| ISPY1_1138 | 3 |
| ISPY1_1140 | 3 |
| ISPY1_1145 | 3 |
| ISPY1_1176 | 2 |
| ISPY1_1215 | 1 |
| ISPY1_1227 | 3 |
| ISPY1_1231 | 3 |
Section 2: Genomic Analysis
Objective: Process microarray expression data to identify predictive and biologically meaningful features associated with treatment response.
1. Subset Radiogenomics
982 patients shared between genomic and radiomics data; 18,348 genes.
2. Keep Protein-Coding Genes
- Retained only protein-coding genes(17,547) based on GENCODE annotations
- Optional: Apply variance filtering to remove low-variance genes
# 1. Subset to common patients
expr_data <- expr[, common_patients] #982
annot_data <- annot[annot$gene_name %in% common_patients , ]
clin_data <- merged_clin[merged_clin$patientid %in% common_patients, ]
# 2. Restrict to Pr-Coding Genes.
annot_proteincoding <- annot[annot$gene_type == "protein_coding",] # 17547 protein coding genes.
expr_data <- expr_data[rownames(expr_data) %in% rownames(annot_proteincoding),]
# Frequency table for the treatment columns
DT::datatable(as.data.frame(table(merged_clin$treatment)),
colnames = c("Treatment", "Count"))# Optional: low varience removal
# plot a density plot
plot(
density(as.numeric(as.matrix(expr_data)), na.rm = TRUE),
main = "Overall Expression Density (All treatments)",
xlab = "Expression",
ylab = "Density"
)
# Plot densities by treatment group
treatments <- unique(na.omit(merged_clin$treatment))
for (treat in treatments) {
patients <- merged_clin$patientid[merged_clin$treatment == treat]
expr_subset <- expr_data[, colnames(expr_data) %in% patients, drop = FALSE]
plot(
density(as.numeric(as.matrix(expr_subset)), na.rm = TRUE),
main = paste("Expression Density:", treat),
xlab = "Expression", ylab = "Density"
)
}
3. Add PredictIO Signatures
(Optional) step: * Loaded 55 curated immune-oncology (IO) RNA
signatures (.rda format) * Each signature derived
from peer-reviewed publications * Signatures used to
assess immune response, sensitivity,
or resistance to immune checkpoint blockade * Mapped to
GENCODE v40 * Sources: * GitHub: bhklab/SignatureSets
* Web app: predictio.ca
# 3. check of how many genes are avaivale in Predio_signitures
sig_path <- file.path(input_dir, "predictIO_sigs")
rda_files <- list.files(sig_path, pattern = "\\.rda$", full.names = TRUE)
summary_list <- list()
# Check gene overlap between IO signatures and expression data
for (file in rda_files) {
sig_obj <- get(load(file))
sig_name <- if ("signature_name" %in% colnames(sig_obj) && length(unique(sig_obj$signature_name)) > 0)
unique(sig_obj$signature_name)[1]
else
tools::file_path_sans_ext(basename(file))
if (!"gene_name" %in% colnames(sig_obj)) next
genes <- sig_obj$gene_name
matched <- intersect(rownames(expr_data), genes)
summary_list[[sig_name]] <- data.frame(
signature = sig_name,
n_genes_total = length(genes),
n_genes_matched = length(matched),
matched_genes = paste(sort(matched), collapse = ", ")
)
}
summary_df <- do.call(rbind, summary_list)
kable(summary_df, caption = "Summary of gene overlap between IO signatures and expression data") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| signature | n_genes_total | n_genes_matched | matched_genes | |
|---|---|---|---|---|
| ADO_Sidders | ADO_Sidders | 14 | 14 | APP, CASP1, CD81, COL3A1, CREB1, CYBB, FOS, FOXP3, GPI, LAG3, MAPK1, MAPK3, PPARG, PTGS2 |
| APM_Thompson | APM_Thompson | 8 | 8 | B2M, CALR, HSP90AB1, NLRC5, PSMB9, PSME1, PSME3, RFX5 |
| APM_Wang | APM_Wang | 18 | 18 | B2M, CALR, CANX, ERAP1, ERAP2, HLA-A, HLA-B, HLA-C, PDIA3, PSMB10, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, TAP1, TAP2, TAPBP |
| Bcell_Budczies | Bcell_Budczies | 8 | 8 | BLK, CD19, FCRL2, MS4A1, PNOC, SPIB, TCL1A, TNFRSF17 |
| Bcell_Helmink | Bcell_Helmink | 66 | 58 | ALG13, AREG, ARHGAP24, ARRDC2, BANK1, BCL11A, BTG1, C9orf72, CALM2, CCR7, CD69, CD83, CHD1, CKS2, CREM, CXCR4, DDX27, DDX3Y, DNAJA1, DNAJB1, DNAJB14, EZR, GPR183, HERPUD1, HSPH1, JUND, KDM6B, LY9, MS4A1, NFKBID, NR4A1, NR4A2, NR4A3, PER1, PRDM2, RANBP2, RASGEF1B, REL, RGPD5, RILPL2, SDCBP, SKIL, SLC2A3, SMCHD1, TGIF1, TRA2A, TSC22D2, TUBA1A, TUBA1C, USP36, VPS37B, WDR45B, WDR74, YPEL5, ZFP36L2, ZNF141, ZNF165, ZNF331 |
| Blood_Friedlander | Blood_Friedlander | 15 | 14 | ADAM17, CDK2, CDKN2A, DPP4, ERBB2, HLA-DRA, ICOS, ITGA4, MYC, NAB2, NRAS, RHOC, TGFB1, TIMP1 |
| C-ECM_Chakravarthy | C-ECM_Chakravarthy | 58 | 55 | A2M, ABI3BP, ACAN, ADAM12, ADAM8, ADAMTS14, COL10A1, COL11A1, COL14A1, COL1A1, COL1A2, COL3A1, COL4A3, COL4A4, COL4A6, COL5A1, COL5A2, COL5A3, COL7A1, COMP, DCN, DDR2, DPT, ECM2, FAP, FBLN1, FBLN5, FGF2, FLRT2, FN1, GPM6B, ITGA9, ITGAX, JAM2, LAMA2, LAMC3, LOXL2, MFAP2, MFAP4, MFAP5, MMP1, MMP11, MMP9, MYH11, PDGFRA, POSTN, RECK, SERPINH1, SPP1, SULF1, TGFBI, TIMP1, TLL1, TNXB, VCAN |
| CCL5-CXCL9_Dangaj | CCL5-CXCL9_Dangaj | 21 | 21 | CCL5, CD2, CD247, CD3E, CD4, CD53, CD86, CD8A, CXCL9, DOCK2, GBP2, GZMK, IL10RA, IL2RB, IRF1, LAPTM5, LCP1, PTPRC, SLC7A7, STAT1, TNFRSF9 |
| CD39-CD8Tcell_Chow | CD39-CD8Tcell_Chow | 23 | 21 | B2M, CD2, CD247, CD96, CXCL13, CXCR6, ENTPD1, GNLY, GZMA, HCST, HLA-B, IKZF3, ITGAL, KLRB1, KLRC1, LCK, LSP1, PDCD1, PTPN22, TNIP3, ZNF683 |
| CD8_Sade-Feldman | CD8_Sade-Feldman | 34 | 32 | BTG2, CD55, CSRNP1, EGR1, FAM177A1, FOSL2, FOXP1, GPR183, IFRD1, IL7R, LMNA, MGAT4A, MYADM, NEU1, NR4A1, NR4A3, PDE4B, PER1, PFKFB3, PIK3R1, REL, RGCC, RGPD5, SKIL, STAT4, TC2N, TCF7, TSC22D2, TSPYL2, USP36, YPEL5, ZFP36L2 |
| Chemokine_Messina | Chemokine_Messina | 12 | 12 | CCL18, CCL19, CCL2, CCL21, CCL3, CCL4, CCL5, CCL8, CXCL10, CXCL11, CXCL13, CXCL9 |
| CIN25_Carter | CIN25_Carter | 25 | 24 | CCNB2, CCT5, CDC45, CDK1, ESPL1, FEN1, FOXM1, KIF20A, MAD2L1, MCM2, MCM7, MELK, NCAPD2, PCNA, PRC1, RAD51AP1, RFC4, RNASEH2A, TGIF2, TOP2A, TPX2, TRIP13, TTK, UBE2C |
| CIN70_Carter | CIN70_Carter | 70 | 67 | ACTL6A, ASF1B, ATAD2, AURKA, AURKB, CCNB1, CCNB2, CCT5, CDC20, CDC45, CDC6, CDCA3, CDCA8, CDK1, CEP55, CKAP5, CKS2, CMAS, CTPS1, DHCR7, DKC1, ECT2, ELAVL1, ESPL1, EZH2, FEN1, FOXM1, HDGF, KIF20A, KIF4A, LSM4, MAD2L1, MCM10, MCM2, MCM7, MELK, MSH6, MTCH2, NCAPD2, NCAPG2, NCAPH, NDUFAB1, NEK2, NUP205, NXT1, OIP5, PBK, PCNA, PDCD2L, PRC1, PTTG1, RAD21, RAD51AP1, RFC4, RNASEH2A, RRM1, RRM2, SRSF2, TGIF2, TOP2A, TPX2, TRIP13, TTK, UBE2C, UNG, ZWILCH, ZWINT |
| COX-IS_Bonavita | COX-IS_Bonavita | 24 | 23 | CCL2, CCL5, CD8A, CD8B, CSF3, CXCL1, CXCL10, CXCL11, CXCL2, CXCL9, EOMES, GZMA, GZMB, IFNG, IL12A, IL12B, IL1A, IL1B, IL6, PRF1, STAT1, TBX21, VEGFA |
| CRMA_Shukla | CRMA_Shukla | 5 | 3 | MAGEA12, MAGEA2B, MAGEA6 |
| CYT_Davoli | CYT_Davoli | 7 | 7 | CD2, CD247, CD3E, GZMH, GZMK, NKG7, PRF1 |
| CYT_Rooney | CYT_Rooney | 2 | 2 | GZMA, PRF1 |
| EMT_Thompson | EMT_Thompson | 12 | 12 | AGER, CDH1, CDH3, CLDN4, EPCAM, FN1, MAL2, MMP2, SNAI2, ST14, VIM, ZEB2 |
| EMTstroma_Wang | EMTstroma_Wang | 18 | 18 | CALD1, CALU, COL6A2, COL6A3, CTHRC1, ECM1, EMP3, FBN1, FLNA, FN1, FOXC2, LAMA2, LOX, LRP1, MFAP5, SERPINE2, TNC, VIM |
| IFN_Ayers | IFN_Ayers | 6 | 6 | CXCL10, CXCL9, HLA-DRA, IDO1, IFNG, STAT1 |
| ImmuneCells_Xiong | ImmuneCells_Xiong | 109 | 97 | ADAM21, ALDH1L2, APBB2, APOC2, ARSF, ASAH2, ASPM, BIRC5, C6orf223, CACNG1, CCL18, CD244, CDCA5, CDH1, CEACAM6, CILP2, CLDN7, CORO7, CR2, CRTAM, CYTL1, DHRS9, DLK1, DUSP13, EIF4A2, ENTHD1, FBLN1, FBLN2, FMOD, FOLR2, FOXI1, GDF1, GIMAP4, GPR31, GRIA1, GRM7, ITGA3, JMJD7, KIR2DL4, KIRREL2, KLHDC8B, KRT4, LALBA, LEF1, LYSMD2, MAEL, MAP2K5, MATN3, MFAP2, MKI67, MMP9, MT1G, MUSK, MXRA8, MYL1, MYO1G, NACA2, NUDT10, NUPR1, OTOF, PKDCC, PLA2G2D, PPA2, PRPH, PRUNE2, RASL12, RIMS2, RNASE1, ROR1, RRM2, SCGB2A2, SH2D2A, SHC3, SLC16A3, SPATA13, SPC24, SPP1, STC1, STC2, STOML3, SYT6, TEAD2, TK1, TM4SF19, TMEM171, TRAF3IP2, TREM2, TRPC4, TSHZ3, TUBA8, TYMS, UBE2C, UNC80, ZNF219, ZNF462, ZNF610, ZNF880 |
| ImmuneScore_Roh | ImmuneScore_Roh | 41 | 40 | CCL3, CCL4, CCL5, CCR5, CXCL10, CXCL11, CXCL9, GNLY, GZMA, GZMB, HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-E, HLA-F, HLA-G, ICAM1, ICAM2, ICAM3, ICAM4, ICAM5, IFNG, IFNGR1, IFNGR2, IRF1, PRF1, PSMB9, STAT1, VCAM1 |
| ImmunoScore_Hao | ImmunoScore_Hao | 76 | 75 | ACAP1, ACP5, AHCYL1, AIM2, ASB2, BIRC5, BTN3A2, CCL13, CCL18, CCL5, CCR2, CCR7, CD2, CD300LF, CD38, CD3D, CD3G, CD6, CD7, CD70, CD8A, CD96, CD97, CDC7, CLECL1, CXCR4, CXCR6, DAXX, DUSP6, EZH2, FADD, FCN1, FCRL3, GMPR, GPRC5C, GRB2, GZMA, HAPLN3, HK3, HLA-DMB, HLA-DOA, HLA-E, HLA-F, ICAM3, IGSF6, IKZF1, IL21R, IL2RB, IRF1, ITGAL, ITK, LAMP3, LCK, LILRA5, LTK, MAK, MLST8, MMP25, NKG7, NOL11, NUCB2, PDCD1, PTGS1, PTGS2, RAET1E, SIRPG, SLC15A3, ST3GAL6, TAP1, TAP2, TAPBP, TBX21, TFEC, TIGIT, UBASH3A |
| IMPRES_Auslander | IMPRES_Auslander | 28 | 26 | BTLA, CD200, CD200R1, CD27, CD274, CD276, CD28, CD40, CD80, CD86, CEACAM1, CTLA4, HAVCR2, IDO1, IL2RB, LAG3, PDCD1, PDCD1LG2, PVR, TIGIT, TNFRSF14, TNFRSF18, TNFRSF4, TNFRSF9, TNFSF4, TNFSF9 |
| IMS_Cui | IMS_Cui | 18 | 18 | ADAM12, AXL, BCAT1, CCL13, CCL2, CCL8, CD163, COL6A3, FAP, IL10, INHBA, ISG15, OLFML2B, PDGFRB, SIGLEC1, STC1, TWIST2, VCAN |
| Inflammatory_Thompson | Inflammatory_Thompson | 27 | 27 | CCL5, CCR5, CD274, CD3D, CD3E, CD8A, CIITA, CTLA4, CXCL10, CXCL11, CXCL13, CXCL9, GZMA, GZMB, HLA-DRA, HLA-DRB1, HLA-E, IDO1, IL2RG, ITGAL, LAG3, NKG7, PDCD1, PRF1, PTPRC, STAT1, TAGAP |
| IPS_Charoentong | IPS_Charoentong | 162 | 152 | ACAP1, ADRM1, AHSA1, AIM2, APOL3, ARHGAP10, ATM, ATP10D, B2M, BIRC3, BRIP1, C1GALT1C1, C3AR1, CASP3, CASQ1, CCL20, CCL4, CCL5, CCNB1, CCR2, CCR5, CCR7, CCT6B, CD14, CD160, CD2, CD27, CD274, CD300E, CD37, CD3D, CD3E, CD3G, CD55, CD69, CD72, CD86, CD8A, CETN3, CFLAR, CLEC5A, CMKLR1, CSE1L, CTLA4, CXCR4, DAPP1, DOCK9, DUSP2, ESCO2, ETS1, EXO1, EXOC6, EXOSC9, EZH2, FCGR2A, FCGR2B, FCGR3A, FERMT3, FLT3LG, FOXP3, GDE1, GEMIN6, GNLY, GPSM3, GPT2, GZMA, GZMH, GZMK, GZMM, HAPLN3, HAVCR2, HLA-A, HLA-B, HLA-C, HLA-DMB, HLA-DPA1, HLA-DPB1, HLA-E, HLA-F, ICOS, IDO1, IFI16, IL18BP, IL2RB, IL34, IL4R, ITGA4, ITGAL, ITGAM, KIF11, KNTC1, L1CAM, LAG3, LCK, LIME1, LIPA, LRP1, LRRC42, LTK, MARCO, MNDA, MPZL1, MRC1, MS4A6A, NCOA4, NFKBIA, NKG7, NUF2, PARVG, PDCD1, PDCD1LG2, PDGFRL, PELO, PIK3IP1, PLEK, PRC1, PRSS23, PSAP, PSAT1, PTGER2, PTGES2, PTGIR, PTGS1, PTRH2, REPS1, RGS1, RTKN2, S100A8, S100A9, SAMSN1, SCG2, SELL, SETD7, SIGLEC6, SIK1, ST8SIA4, STAB1, TAL1, TAP1, TAP2, TFEC, TIGIT, TIMM13, TIPIN, TPK1, TRAT1, TRIB2, UQCRB, USP9Y, WIPF1, ZAP70, ZCRB1 |
| IRG_Ayers | IRG_Ayers | 17 | 17 | CCL5, CD2, CD3D, CD3E, CIITA, CXCL10, CXCL13, CXCR6, GZMB, GZMK, HLA-DRA, HLA-E, IDO1, IL2RG, NKG7, STAT1, TAGAP |
| IRG_Yang | IRG_Yang | 11 | 11 | ANGPTL5, IFI30, IGF1, LEPR, NR2F2, NRP1, PLAU, PRL, PRLHR, TNFRSF10A, TNFRSF10B |
| KDM5A_Wang | KDM5A_Wang | 8 | 8 | ANO3, FAM13C, HMCN1, IKZF3, KDM5A, MVB12B, PDE1A, RIOK1 |
| M1_Hwang | M1_Hwang | 13 | 12 | CBLB, CCR7, CD27, CD48, FOXO1, HLA-B, HLA-G, IFIH1, IKZF4, LAMP3, NFKBIA, SAMHD1 |
| Macrophage_Danaher | Macrophage_Danaher | 4 | 4 | CD163, CD68, CD84, MS4A4A |
| MHC-I_Liu | MHC-I_Liu | 8 | 8 | B2M, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, TAP1, TAP2 |
| MHC-II_Liu | MHC-II_Liu | 13 | 13 | HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB5 |
| MPS_Guijarro | MPS_Guijarro | 45 | 42 | AKR1C3, ALX1, BMP1, BRD7, CRTAC1, DTD1, ECEL1, ERC2, FAM110C, FUT9, GABRA2, GAP43, GREM1, GRSF1, HCN1, HECW1, KLHL1, KRT12, LHFPL4, LTA4H, NEFM, NETO1, NKX2-2, OCIAD2, OTOP1, OXCT1, PDE3B, PLXNC1, PTPRN2, PTPRT, SIGLEC15, SLC13A5, SLC9A2, SLITRK6, SNAP91, SSBP4, STON2, TAC1, TELO2, TMEM177, VAT1L, WNT5A |
| Myeloid-DC_Helmink | Myeloid-DC_Helmink | 6 | 5 | CD1A, CD1B, CD1E, CLEC10A, CLIC2 |
| NonResponse_Chen | NonResponse_Chen | 258 | 241 | ACTL6A, ALYREF, ANLN, APOBEC3A, ASPM, ATAD2, AUNIP, AURKA, AURKB, BIRC5, BLM, BOP1, BORA, BRIX1, BUB1, BYSL, CBX2, CCDC138, CCDC167, CCNA2, CCNB1, CCNB2, CCNE1, CCNE2, CCT3, CDC123, CDC20, CDC25A, CDC25C, CDC45, CDC7, CDCA2, CDCA3, CDCA5, CDCA7, CDCA8, CDK1, CDK4, CDKN3, CENPA, CENPE, CENPF, CENPI, CENPK, CENPL, CENPM, CENPN, CENPO, CENPW, CEP55, CHCHD3, CHEK1, CHEK2, CKAP2L, CKS1B, CKS2, CMC2, CMSS1, CSE1L, CTPS1, CTSV, DEPDC1B, DHFR, DIAPH3, DKC1, DLGAP5, DNAJC9, DONSON, DSCC1, DTL, E2F2, ECE2, ECT2, ENY2, ERCC6L, ESPL1, EXO1, EZH2, FAM72D, FAM83D, FAM91A1, FANCB, FANCD2, FANCI, FBXO5, FEN1, FOXM1, GABPB1, GGH, GINS3, GMPS, GPSM2, GTPBP4, HDGF, HELLS, HJURP, HMMR, HPRT1, HSPA14, HSPD1, ILF2, KIF11, KIF14, KIF15, KIF18A, KIF20A, KIF23, KIF2C, KIF4A, KIFC1, KPNA2, LIN9, LMNB1, LMNB2, LRP8, LRR1, LYAR, MAD2L1, MASTL, MCM10, MCM2, MCM3, MCM4, MCM6, MCM7, MELK, MND1, MRPL13, MRPL15, MRPL3, MRPL42, MRPS17, MSH6, MTFR1, MTHFD2, NCAPG, NCAPG2, NCBP2, NDC1, NDC80, NEIL3, NEK2, NME1, NOLC1, NOP16, NOP58, NUDT5, NUF2, NUP155, NUP205, NUSAP1, OIP5, ORC1, ORC6, PARPBP, PBK, PCNA, PDCD5, PDSS1, PGAM5, PHF19, PKMYT1, PLK1, PLK4, PNP, POC1A, POLE2, POLQ, POLR2D, POP1, PPAT, PRC1, PRDX4, PRR11, PSMD12, PSMD14, PSMG1, PTTG1, RACGAP1, RAD51, RAD51AP1, RAD54B, RAD54L, RANBP1, RFC2, RFC3, RFC4, RIPK2, RNASEH2A, RPL29, RPL34, RPL6, RPL8, RPS21, RPS24, RRM2, SEH1L, SMC2, SNRPA1, SNRPC, SNRPD1, SNRPF, SNRPG, SPAG5, SPC25, SPDL1, SRPK1, STIL, STMN1, TACC3, TICRR, TIMELESS, TIMM8A, TIPIN, TMPO, TOMM5, TOP2A, TPX2, TRIP13, TROAP, TTK, TUBA1B, TUBA1C, TXN, TYMS, UBE2C, UBE2S, UBE2T, UBE2V2, UBQLN1, UCHL5, UCK2, UNG, UQCRB, UQCRH, VRK1, WDR12, WDR43, XPOT, ZNF670, ZWINT |
| PDL1_Nishino | PDL1_Nishino | 3 | 3 | CD274, PDCD1, PDCD1LG2 |
| peri-Tcell_Hwang | peri-Tcell_Hwang | 3 | 3 | GPR18, HLA-DOA, STAT1 |
| PredictIO_Bareche | PredictIO_Bareche | 100 | 98 | ABCD2, ANP32E, APOL6, ARHGAP24, B2M, C14orf132, CA2, CD3E, CD3G, CD83, CD8A, CRYAB, CST7, CTSW, CXCL10, CXCL11, CXCL13, CXCL9, CXCR6, DAPK1, DLG4, DOCK8, EAF1, EOMES, EPB41, ERI1, F11R, F2RL1, FASLG, FBXO6, FGD3, FHL3, FJX1, GALNT5, GBP1, GBP4, GBP5, GCNT4, GLE1, GMIP, GNLY, GZMA, GZMB, GZMK, HPGD, IFIT5, IKZF3, IQUB, JAKMIP1, KLHDC7B, KLRD1, LAG3, LCK, LPAR1, LY9, MAST1, MS4A1, MYCL, NKG7, NUB1, P2RY10, PCDHGB6, PDCD1, PDGFA, PLA2G2D, PLCL2, POLE, PPM1D, PRF1, PRKCH, PSMB9, PSME1, PTPRCAP, RAB11FIP1, RAB11FIP4, RAB20, RAB42, RAB8A, RBFOX2, RCBTB2, RPS6KA5, SELL, SLAMF1, SLAMF7, SLC20A2, SLC9C1, SORCS2, SOX9, SPINK5, SYK, TAGAP, TBX21, TRAFD1, TXNDC11, VSNL1, XPC, ZBED2, ZHX3 |
| proliferation_Pabla | proliferation_Pabla | 10 | 9 | BUB1, CCNB2, CDK1, CDKN3, FOXM1, MAD2L1, MELK, MKI67, TOP2A |
| PTEN-MITF_Cabrita | PTEN-MITF_Cabrita | 263 | 244 | ADAMDEC1, ANGPT1, ANKRD22, ANTXR1, APOE, ARL6IP5, ASB9, ATP2B1, AUTS2, BACE2, BCAT1, BCL2A1, BHLHE41, BIRC3, BIRC7, C2orf88, CABLES1, CADM1, CAPN3, CASP1, CBR3, CBX2, CCL5, CD38, CD3D, CD44, CD48, CD52, CD79A, CD79B, CD8A, CDH2, CDK14, CDK6, CEACAM1, CENPV, CHCHD6, CLIP3, CNPY4, COL12A1, COL16A1, COL5A1, COL5A2, COL8A1, CPE, CPXM1, CSTB, CXCL10, CXCL13, CXCL9, DACT3, DDAH1, DIAPH3, DKK3, DPYSL3, ECHDC3, EDNRA, EFEMP2, EFNB2, EMILIN1, ENAH, ENC1, ERRFI1, ESM1, EXTL2, FBXO6, FBXW5, FCRLA, FOXC1, FSCN1, FZD1, FZD2, GBP5, GMPR, GNPTAB, GPC6, GPNMB, GSDMD, GSTO1, GYG2, GZMB, HCST, HERC5, HIGD1A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HOXA5, HOXB5, HPS1, HRK, HSD17B14, ID1, ID3, IFI27, IFI35, IFIH1, IGFBP2, IL18BP, INPP4B, IRF1, IRF4, IRF8, ISG20, ITGB5, ITGB7, KAT2B, KDM5B, KLF12, LAMB1, LAMC1, LGALS3, LIMCH1, LMNB2, LOX, LRP5, LY96, LYN, LYST, MAZ, MBP, MCOLN2, MCOLN3, MEIS2, MFSD6, MICAL1, MITF, MLANA, MLLT11, MOXD1, MYO5A, NCF1, NKG7, NR4A2, NREP, NSG1, NTM, OAS2, OLFML2A, OSTM1, P2RX7, PAM, PARP10, PARP9, PCDH17, PCDH18, PCOLCE, PEG10, PHACTR1, PHLDB2, PIR, PKIA, PLA1A, PLEK, PLXNC1, PMEPA1, POSTN, PRDM8, PRICKLE1, PRICKLE2, PRKCB, PRKCD, PSMB8, PSMB9, PXDN, QPCT, RAB27A, RAB32, RAB38, RAC2, RBBP4, RBP1, RCAN2, RENBP, RGS10, RGS4, ROPN1, ROPN1B, RPS6KA5, RTP4, RUNX3, S100A1, S1PR3, SALL2, SAT1, SBK1, SDC2, SDCBP, SERPINB1, SIGIRR, SKP2, SLC11A2, SLC45A2, SLC9A3R1, SLIT2, SNCA, SNX10, SOCS2, SOD2, SOX13, SOX4, SPRY1, SPRY2, ST3GAL6, ST6GALNAC2, STAT1, STK32B, STX7, SWAP70, SYT11, TAP1, TAPBP, TBC1D7, TCF12, TCF3, TLE4, TMEM140, TMEM47, TMSB15A, TMTC4, TNFRSF14, TRIB1, TRIM63, TRO, TRPV2, TSPAN5, TUSC3, TYR, TYSND1, UBA52, UBD, UBE2E3, UBE2L6, UPP1, VAT1, VCAN, VNN2, ZNF286A, ZNF395, ZNF512, ZNF532, ZNF84 |
| Response_Chen | Response_Chen | 443 | 414 | ABI3, ABI3BP, ACAP1, ACSL5, ACVRL1, ADA, ADAM7, ADAP2, ADCY7, AIM2, AKNA, ALOX5, ANXA2R, APBB1IP, APOBEC3C, APOBEC3G, APOBEC3H, APOE, ARHGAP15, ARHGAP25, ARHGAP30, ARHGAP4, ARHGAP9, ARHGEF1, ARHGEF18, ARRDC5, BACH2, BANK1, BATF3, BCL11B, BIN1, BIRC3, BLK, BTK, BTLA, BTN3A1, BTN3A2, BTN3A3, C1orf162, C1QA, C1QC, C2, CAPN3, CARD11, CASP1, CCL19, CCL22, CCL5, CCM2, CCND2, CCR2, CCR7, CD19, CD1B, CD1C, CD2, CD22, CD247, CD27, CD28, CD37, CD3D, CD3E, CD3G, CD4, CD40, CD40LG, CD48, CD5, CD52, CD53, CD6, CD7, CD72, CD74, CD79A, CD79B, CD84, CD86, CD8A, CELF2, CETP, CHKB, CLECL1, CMKLR1, CORO1A, CR2, CSF1R, CSF2RA, CSK, CST7, CTLA4, CTSW, CXCL9, CXCR3, CXCR5, CXCR6, CXorf65, CYBB, CYTH1, CYTIP, DAB2, DEF6, DENND1C, DENND3, DGKA, DNAH1, DNASE1L3, DOCK10, DOCK11, DOCK2, DOCK8, DOK2, DOK3, DPEP2, EFHD2, EHD1, ELMO1, EML3, EMP3, ENG, EOMES, ETS1, EVI2B, FAM78A, FCAR, FCER2, FCHSD2, FCN1, FCRL3, FCRL5, FERMT3, FGD2, FGR, FNBP1, FYN, GAB3, GAS7, GBP2, GBP4, GBP5, GIMAP4, GIMAP5, GIMAP6, GIMAP7, GMFG, GMIP, GNAI2, GNGT2, GNLY, GPR132, GPR18, GPSM3, GRAP, GZMA, GZMB, GZMH, GZMK, HCLS1, HCST, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPB1, HLA-E, HLA-F, HLX, HVCN1, ICAM2, ICAM3, ICOS, IFFO1, IFNAR2, IGFLR1, IGSF6, IL10RA, IL12RB1, IL15, IL16, IL18BP, IL18R1, IL18RAP, IL21R, IL2RG, IL32, IL4R, IL7R, INPP5D, IPCEF1, IRF1, IRF8, ITGAX, ITGB2, ITGB7, ITK, KBTBD8, KIF21B, KLHL6, KLRB1, KLRD1, KLRG1, LAG3, LAPTM5, LAT, LAT2, LBH, LCK, LCP1, LCP2, LGALS2, LGALS9, LILRB3, LILRB4, LIME1, LPXN, LSP1, LST1, LTA, LTB, LY86, LY9, LYL1, LYN, MAL, MAN2B1, MAP4K1, MATK, MCOLN2, MEF2C, MEI1, MGAT1, MICAL1, MOB3A, MSC, MSN, MX2, MYCBP2, MYO1F, MYO1G, MYO9B, NAGK, NAPSA, NCF1, NCF4, NCKAP1L, NCR3, NFS1, NKG7, NLRC5, NLRP1, NLRP3, NPSR1, NR1H3, NRROS, P2RY10, P2RY8, PAG1, PAPLN, PAQR8, PARP15, PARVG, PBX4, PCSK7, PDCD1, PDE4DIP, PIK3CD, PIK3IP1, PIP4K2A, PITPNM2, PLAC8, PLCB2, PLCG2, PLCL2, PLEK, PLEKHA2, PLEKHO1, PLEKHO2, PNOC, POU2AF1, POU2F2, PPM1M, PPP1R16B, PPP1R18, PRAM1, PRDM8, PRF1, PRKCB, PRKCH, PSMB10, PSTPIP1, PTGDS, PTGER4, PTK2B, PTPN6, PTPN7, PTPRC, PTPRCAP, PVRIG, PYHIN1, RAB33A, RAB37, RAB8B, RAC2, RAPGEF1, RASAL3, RASGRP2, RASGRP3, RASSF2, RASSF4, RASSF5, RCSD1, RENBP, RFTN1, RGL4, RGS19, RHOF, RHOG, RIN3, RNF166, RUNX3, S1PR4, SAMD3, SAP25, SASH3, SCIMP, SEL1L3, SELL, SELPLG, SEMA4D, SERPING1, SH2B3, SH2D1A, SH2D3C, SH3BGRL3, SH3BP1, SH3KBP1, SH3TC1, SIPA1, SIRPA, SLA, SLA2, SLAMF1, SLAMF7, SLC15A3, SLC1A3, SLC7A6, SLC7A7, SLC9A9, SLCO2B1, SMAP2, SOCS1, SP140, SPI1, SPNS3, SPOCK2, ST3GAL5, ST8SIA4, STAB1, STAT2, STAT4, STK10, STK4, SYK, SYNE3, SYT11, TAGAP, TAPBP, TBC1D10C, TBC1D2B, TBXAS1, TCF4, TCIRG1, TCL1A, TESPA1, TIMD4, TLN1, TLR10, TLR9, TMEM119, TMEM140, TNFAIP3, TNFRSF13B, TNFRSF14, TNFRSF1B, TNFRSF25, TNFRSF4, TNFRSF6B, TNFSF13, TNFSF14, TNIP1, TOX2, TRAF1, TRAF3IP3, TRANK1, TRAT1, TRIM38, TRPV2, TXK, UBASH3A, VAMP5, VASH1, VAV1, VCAM1, VPREB3, WAS, WIPF1, XAF1, ZAP70, ZBED2, ZBTB32, ZNF366, ZNF683, ZNF831 |
| STAT1_Care | STAT1_Care | 39 | 37 | ANKRD22, APOL3, APOL6, CCL4, CCR5, CD2, CST7, CXCL10, CXCL11, CXCL9, CXCR6, FCER1G, FCGR1B, FGL2, GBP1, GBP2, GBP4, GBP5, GIMAP4, GIMAP5, GZMA, GZMK, IDO1, IFIT3, IFNG, IRF1, LAG3, LAP3, PRF1, SERPINA1, SERPING1, SLAMF7, SLC31A2, STAT1, TAP1, TNFSF10, XAF1 |
| Tcell-exclusion_Arnon | Tcell-exclusion_Arnon | 108 | 94 | APOD, APOE, ATIC, ATP1A1, B2M, BTF3, CAPN3, CD63, CDH1, CHCHD2, CTSD, DAAM2, EEF1G, EIF3G, EIF3M, EIF4A1, ENO1, EXOSC4, FARSA, GAPDH, GPNMB, HLA-A, HLA-B, HLA-C, HLA-F, HNRNPA1, HPS5, HSP90AA1, IFI27, IRF4, LGALS3, LGALS3BP, LSM7, MAGEA4, MAGEC1, MCAM, MDH2, MLLT11, MRPS24, NACA, NDUFB9, NME1, NREP, NSG1, PLXNC1, PSAP, QPCT, RAB5B, RPL18A, RPL19, RPL26, RPL27A, RPL31, RPL32, RPL35A, RPL36, RPL37, RPL37A, RPL39, RPL6, RPL7, RPLP2, RPS11, RPS13, RPS14, RPS15, RPS16, RPS17, RPS18, RPS20, RPS21, RPS23, RPS25, RPS27A, RPS28, RPS4X, RPS5, RPS6, S100A1, S100B, SAT1, SEC11C, SLC7A8, SMARCA4, SNRPD2, ST3GAL6, STOML2, TIMM13, TMED10, TMEM255A, TPI1, TYR, UBA52, VAT1 |
| Teff-IFNG_Fehrenbacher | Teff-IFNG_Fehrenbacher | 8 | 8 | CD8A, CXCL10, CXCL9, EOMES, GZMA, GZMB, IFNG, TBX21 |
| Teff_McDermott | Teff_McDermott | 5 | 5 | CD274, CD8A, EOMES, IFNG, PRF1 |
| TGFB_Mariathasan | TGFB_Mariathasan | 19 | 17 | ACTA2, ACTG2, ADAM12, ADAM19, CNN1, COL4A1, CTPS1, FSTL3, HSPB1, IGFBP3, PXDC1, SEMA7A, SH3PXD2A, TAGLN, TGFBI, TNS1, TPM1 |
| TIS_Damotte | TIS_Damotte | 18 | 18 | CCL5, CD27, CD274, CD276, CD8A, CMKLR1, CXCL9, CXCR6, HLA-DQA1, HLA-DRB1, HLA-E, IDO1, LAG3, NKG7, PDCD1LG2, PSMB10, STAT1, TIGIT |
| TLS_Cabrita | TLS_Cabrita | 9 | 9 | CCR6, CD1D, CD79B, CETP, EIF1AY, LAT, PTGDS, RBP5, SKAP1 |
| TUMOR-VASCULATURE-UP_Lu | TUMOR-VASCULATURE-UP_Lu | 29 | 29 | ADAM12, ADAP2, CHN1, CMTM8, COL5A3, EGFL6, FJX1, FOXF2, FZD10, HOPX, HSPA6, ISG15, LCP2, MMP9, MUC1, MXRA5, PAMR1, PLXDC1, PMAIP1, POSTN, RPS11, SCIN, SPP1, STC1, TNFAIP6, TNFRSF21, TWIST1, VCAN, WDR77 |
| VIGex_Hernando-Calvo | VIGex_Hernando-Calvo | 12 | 12 | CD274, CTLA4, CXCL10, CXCL11, CXCL9, FOXP3, GZMA, GZMB, IFNG, IL7R, PDCD1, PRF1 |
Full dataset analysis (no subsetting)
# Design and model
design_full <- model.matrix(~ clin_data$response)
fit_full <- eBayes(lmFit(expr_data, design_full))
top_full <- topTable(fit_full, sort.by = "P", n = Inf)
top_full$Gene <- rownames(top_full)
# Save results
write.table(top_full, file.path(output_dir,"DEG_analysis", "full_limma_fit.txt"),
sep = "\t", quote = FALSE, row.names = FALSE)
# Display table
DT::datatable(round(top_full[sapply(top_full, is.numeric)], 3),
caption = "TopTable - Full")# Volcano plot
top_clean <- top_full[, sapply(top_full, is.numeric)]
rownames(top_clean) <- top_full$Gene
print(EnhancedVolcano(top_full,
lab = rownames(top_full),
x = 'logFC',
y = 'P.Value',
pCutoff = 0.05,
FCcutoff = 1.5,
xlim = c(-3, 3),
ylim = c(0, 20),
title = paste("Volcano Plot (P value)")
))
# Volcano plot: FDR
print(EnhancedVolcano(top_full,
lab = rownames(top_full),
x = 'logFC',
y = 'adj.P.Val',
pCutoff = 0.05,
FCcutoff = 1.5,
xlim = c(-3, 3),
ylim = c(0, 20),
legendLabels = c('Not sig.', 'Log FC', 'adj p-value', 'adj p-value & Log FC'),
title = paste("Volcano Plot (FDR) ")
))
# Summary
sig_genes_full <- rownames(top_full)[top_full$adj.P.Val < 0.05 & abs(top_full$logFC) >= 1.5]
cat("DE genes (adj.P.Val < 0.05):", sum(top_full$adj.P.Val < 0.05), "\n")DE genes (adj.P.Val < 0.05): 5870
DE genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5): 0
No Significant gene names:
character(0)
5. Pathway Enrichment
MSigDB Hallmark Gene Sets
- Gene sets downloaded from MSigDB
- Analysis: GSEA using the
fgseaR package - Input: ranked gene list from differential expression results
# Load human hallmark gene sets from MSigDB
pathwaysDF <- msigdbr("Homo sapiens", category="H")
# Create a list of gene symbols for each pathway
pathwaysH <- split(as.character(pathwaysDF$gene_symbol), pathwaysDF$gs_name)
# 1. Create ranks
# Create 'ranks' vector from 'top.table' with logFC as values and gene names as names.
ranks <- top_full$logFC
names(ranks) <- top_full$Gene
ranks <- sort(ranks, decreasing = T)
# Preview the data table of ranks.
kable(ranks) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| x | |
|---|---|
| S100A8 | 1.3850785 |
| CCL18 | 1.1434526 |
| S100A9 | 1.1320002 |
| MMP1 | 1.0863855 |
| CXCL9 | 1.0839579 |
| UBD | 1.0458175 |
| CXCL13 | 1.0326681 |
| IDO1 | 1.0178867 |
| SOX11 | 0.9947555 |
| S100A7 | 0.9933994 |
| CALML5 | 0.9652130 |
| GBP5 | 0.9569267 |
| POU2AF1 | 0.9293084 |
| GZMB | 0.9134147 |
| CD38 | 0.8987808 |
| TNFRSF17 | 0.8837390 |
| PPP1R1B | 0.8783770 |
| RARRES1 | 0.8604521 |
| IGLL1 | 0.8036213 |
| MARCO | 0.7989275 |
| LAMP3 | 0.7974185 |
| KRT86 | 0.7973198 |
| SLAMF7 | 0.7956771 |
| CXCL10 | 0.7851975 |
| MZB1 | 0.7807303 |
| PNMT | 0.7685745 |
| GRB7 | 0.7637936 |
| CCL13 | 0.7589612 |
| KRT81 | 0.7589158 |
| GLYATL2 | 0.7440797 |
| FDCSP | 0.7228458 |
| VGLL1 | 0.7146038 |
| KLHDC7B | 0.7122132 |
| CCL5 | 0.7096057 |
| CD19 | 0.7006908 |
| DEFB1 | 0.6873511 |
| CCL8 | 0.6834228 |
| CXCL11 | 0.6810084 |
| FAM26F | 0.6697862 |
| PSAT1 | 0.6691349 |
| AIM2 | 0.6690814 |
| LYZ | 0.6657482 |
| GBP1 | 0.6657354 |
| LAG3 | 0.6638736 |
| TMSB15A | 0.6625949 |
| CD2 | 0.6618834 |
| ZBED2 | 0.6613328 |
| CD27 | 0.6610416 |
| KRT7 | 0.6564974 |
| CD79A | 0.6556491 |
| IL21R | 0.6540160 |
| DCD | 0.6513482 |
| SMR3A | 0.6457189 |
| PNOC | 0.6433911 |
| PPP1R14C | 0.6354700 |
| CDH3 | 0.6293015 |
| TCL1A | 0.6265711 |
| CCR7 | 0.6243550 |
| IGJ | 0.6242737 |
| CD3D | 0.6236595 |
| PROM1 | 0.6146861 |
| NMU | 0.6136748 |
| IL4I1 | 0.6079146 |
| HSD17B2 | 0.6073983 |
| LTB | 0.6031957 |
| CCL4 | 0.5962834 |
| SLAMF8 | 0.5937734 |
| STAC2 | 0.5872901 |
| MUCL1 | 0.5855715 |
| FUT3 | 0.5851305 |
| NYX | 0.5814667 |
| GZMA | 0.5811556 |
| CYTIP | 0.5764298 |
| KRT23 | 0.5764271 |
| TRPV6 | 0.5748127 |
| GZMK | 0.5747942 |
| DKK1 | 0.5734656 |
| KIAA0125 | 0.5712151 |
| WARS | 0.5711957 |
| CPNE5 | 0.5706374 |
| TCAP | 0.5690387 |
| GNLY | 0.5681792 |
| EGFL6 | 0.5674976 |
| FABP7 | 0.5666536 |
| PIM2 | 0.5642276 |
| PDCD1 | 0.5592628 |
| BBOX1 | 0.5583286 |
| TAP1 | 0.5562940 |
| HAPLN3 | 0.5554008 |
| GZMH | 0.5514987 |
| LCK | 0.5498950 |
| ZNF683 | 0.5486613 |
| CXCL17 | 0.5470079 |
| TXNDC5 | 0.5435695 |
| GBP4 | 0.5434831 |
| SOD2 | 0.5425075 |
| S1PR4 | 0.5417795 |
| PHGDH | 0.5387533 |
| NKG7 | 0.5386368 |
| PSMD3 | 0.5385507 |
| LCN2 | 0.5375737 |
| PTGDS | 0.5369307 |
| MIEN1 | 0.5343650 |
| STARD3 | 0.5275384 |
| IL2RB | 0.5274443 |
| BATF2 | 0.5229919 |
| LY6D | 0.5228244 |
| PVRIG | 0.5227094 |
| GABRP | 0.5202545 |
| KLK8 | 0.5184354 |
| TIGIT | 0.5172658 |
| B3GNT3 | 0.5164388 |
| ICOS | 0.5160900 |
| CRABP1 | 0.5140264 |
| WNT6 | 0.5126218 |
| HIST1H1A | 0.5101229 |
| LAD1 | 0.5097289 |
| STAT1 | 0.5071251 |
| NANOS1 | 0.5040484 |
| HLA-DQB2 | 0.5034304 |
| IRF4 | 0.5012674 |
| CHI3L2 | 0.4928142 |
| CD3G | 0.4918653 |
| PCP4L1 | 0.4885043 |
| CD247 | 0.4866781 |
| GSTA5 | 0.4851778 |
| CDKN2A | 0.4851177 |
| CXCL1 | 0.4824368 |
| TDO2 | 0.4810336 |
| CHI3L1 | 0.4803812 |
| HLA-F | 0.4796175 |
| C1QA | 0.4781693 |
| KRT17 | 0.4774839 |
| PSMB9 | 0.4773345 |
| CXCR3 | 0.4768548 |
| CCNE1 | 0.4765488 |
| GPR171 | 0.4761948 |
| MEX3A | 0.4745969 |
| ISG20 | 0.4743085 |
| CCL2 | 0.4734924 |
| C1QB | 0.4734545 |
| CCR5 | 0.4729445 |
| CD52 | 0.4726944 |
| GSDMB | 0.4725802 |
| ICAM1 | 0.4703538 |
| PFKP | 0.4698684 |
| KCNG1 | 0.4695368 |
| ITM2C | 0.4691700 |
| SEL1L3 | 0.4687432 |
| PGAP3 | 0.4677950 |
| IL32 | 0.4677122 |
| CLCA2 | 0.4671760 |
| CXCR6 | 0.4669572 |
| CCL7 | 0.4668918 |
| MYCN | 0.4662222 |
| ADAMDEC1 | 0.4637067 |
| ROPN1 | 0.4627056 |
| C1orf106 | 0.4619162 |
| TNFSF13B | 0.4610545 |
| CCL17 | 0.4605624 |
| TBX21 | 0.4602236 |
| CCL19 | 0.4600060 |
| P2RY6 | 0.4574165 |
| EAF2 | 0.4571497 |
| ST6GAL1 | 0.4571121 |
| TRAF3IP3 | 0.4559037 |
| PTPRCAP | 0.4541002 |
| CCL3 | 0.4526464 |
| COL4A4 | 0.4514899 |
| EFS | 0.4505822 |
| DAPP1 | 0.4503117 |
| ETV7 | 0.4496546 |
| CD6 | 0.4483874 |
| HLA-DRA | 0.4479487 |
| TBC1D10C | 0.4468485 |
| CD53 | 0.4460939 |
| HCST | 0.4454721 |
| LILRB3 | 0.4449828 |
| PLA2G7 | 0.4421087 |
| CP | 0.4417872 |
| FAM3D | 0.4375691 |
| HLA-DPA1 | 0.4370586 |
| XCL1 | 0.4355630 |
| HLA-DRB5 | 0.4354076 |
| HLA-DRB1 | 0.4341736 |
| LCP1 | 0.4339514 |
| SLPI | 0.4337239 |
| HLA-E | 0.4332669 |
| GAL | 0.4331002 |
| IFNG | 0.4322959 |
| FADS2 | 0.4307643 |
| XCL2 | 0.4303177 |
| FKBP11 | 0.4297693 |
| GIMAP5 | 0.4296121 |
| CLEC4E | 0.4290977 |
| BANK1 | 0.4277823 |
| NLRP7 | 0.4268740 |
| B3GNT5 | 0.4249782 |
| MMP9 | 0.4210249 |
| CDCA7 | 0.4206268 |
| TMEM45A | 0.4200200 |
| HSD11B1 | 0.4186542 |
| IFI30 | 0.4181884 |
| IRF1 | 0.4168068 |
| LTF | 0.4166539 |
| LGALS2 | 0.4161137 |
| GALNT14 | 0.4158044 |
| ORM2 | 0.4155995 |
| COL9A3 | 0.4142167 |
| BIRC3 | 0.4138371 |
| CCL3L3 | 0.4131763 |
| SIT1 | 0.4123435 |
| HLA-DQA2 | 0.4116911 |
| TRIM29 | 0.4114497 |
| CD8A | 0.4107074 |
| CD79B | 0.4094244 |
| SH2D2A | 0.4073098 |
| CORO1A | 0.4070454 |
| ANXA3 | 0.4062726 |
| FASLG | 0.4058934 |
| IGF2BP3 | 0.4051887 |
| KYNU | 0.4042375 |
| C1QC | 0.4029574 |
| NUDT8 | 0.4022472 |
| KLK5 | 0.4009160 |
| C17orf96 | 0.4004112 |
| ASS1 | 0.3997093 |
| CD5 | 0.3992069 |
| IDH2 | 0.3988369 |
| ARL9 | 0.3983356 |
| GSTA2 | 0.3963213 |
| MNX1 | 0.3950176 |
| IGFLR1 | 0.3949745 |
| ZAP70 | 0.3940882 |
| GPR183 | 0.3933396 |
| MMP3 | 0.3913860 |
| ORMDL3 | 0.3905396 |
| PDZK1IP1 | 0.3901984 |
| HLA-A | 0.3899421 |
| CYBB | 0.3891377 |
| PLEK | 0.3883532 |
| CD48 | 0.3880726 |
| ACE2 | 0.3879054 |
| ERBB2 | 0.3872352 |
| KCNN4 | 0.3871849 |
| LILRB2 | 0.3867208 |
| PLCG2 | 0.3858359 |
| CHST11 | 0.3855673 |
| RGL4 | 0.3845609 |
| FCGR1B | 0.3835191 |
| SOCS1 | 0.3831187 |
| HCLS1 | 0.3829338 |
| ITGB7 | 0.3814530 |
| JSRP1 | 0.3810312 |
| SLC7A7 | 0.3805421 |
| ZBP1 | 0.3804669 |
| CD96 | 0.3799172 |
| MAL | 0.3798783 |
| KRT16 | 0.3796895 |
| ACTL8 | 0.3791262 |
| HLA-DMA | 0.3776115 |
| VTCN1 | 0.3764346 |
| MMP7 | 0.3760805 |
| IL10RA | 0.3755800 |
| MELK | 0.3749998 |
| KIF1A | 0.3749996 |
| P2RY8 | 0.3735646 |
| HLA-DPB1 | 0.3706516 |
| KLRB1 | 0.3701256 |
| HLA-C | 0.3698873 |
| HLA-B | 0.3692516 |
| ORM1 | 0.3689933 |
| ACTG2 | 0.3687850 |
| CD74 | 0.3681222 |
| SLAMF1 | 0.3681120 |
| FGFBP1 | 0.3678127 |
| PM20D2 | 0.3669306 |
| CSRP2 | 0.3667279 |
| IL12RB2 | 0.3662288 |
| PTPN7 | 0.3654962 |
| GPRIN2 | 0.3651123 |
| FAM49A | 0.3648710 |
| SPCS3 | 0.3647517 |
| GABBR2 | 0.3646907 |
| LAPTM5 | 0.3631916 |
| CENPW | 0.3603389 |
| PDK1 | 0.3590239 |
| CD70 | 0.3564888 |
| ZC4H2 | 0.3561108 |
| KLRG2 | 0.3558844 |
| CTSC | 0.3546270 |
| FCRL5 | 0.3545776 |
| VAV1 | 0.3542093 |
| GSTA1 | 0.3540657 |
| GPR126 | 0.3537022 |
| ANXA2R | 0.3529508 |
| TNS4 | 0.3526886 |
| C2orf54 | 0.3526884 |
| VCAM1 | 0.3510003 |
| GHRL | 0.3506863 |
| GIMAP7 | 0.3506819 |
| KRT6A | 0.3500335 |
| RASSF4 | 0.3498467 |
| ROPN1B | 0.3495164 |
| CD163 | 0.3485973 |
| VNN2 | 0.3483673 |
| FOXC1 | 0.3480929 |
| KIF2C | 0.3480348 |
| C2 | 0.3480231 |
| ZNF831 | 0.3479948 |
| CDC45 | 0.3466702 |
| CENPA | 0.3463336 |
| ABRACL | 0.3459351 |
| GSTP1 | 0.3458692 |
| DPEP3 | 0.3451624 |
| COTL1 | 0.3446105 |
| TMSB15B | 0.3444800 |
| IL2RG | 0.3436939 |
| THEMIS2 | 0.3435251 |
| TTYH1 | 0.3434137 |
| PRKX | 0.3433775 |
| HLA-DQB1 | 0.3433603 |
| TFRC | 0.3431881 |
| CTSV | 0.3431612 |
| NCF1 | 0.3428172 |
| LAX1 | 0.3422780 |
| HRK | 0.3419301 |
| AQP5 | 0.3417451 |
| AMICA1 | 0.3415933 |
| ANKRD22 | 0.3414978 |
| ARHGAP9 | 0.3406020 |
| EPHB6 | 0.3405115 |
| IMPA2 | 0.3402292 |
| SASH3 | 0.3399722 |
| CD97 | 0.3398194 |
| KLHL6 | 0.3396713 |
| CCR2 | 0.3393446 |
| GALNT3 | 0.3393409 |
| FAM46C | 0.3392439 |
| LMO4 | 0.3389611 |
| TNFRSF8 | 0.3386100 |
| CHODL | 0.3373857 |
| NCF2 | 0.3371489 |
| SYK | 0.3366901 |
| S100P | 0.3362015 |
| AQP9 | 0.3359032 |
| LCP2 | 0.3358369 |
| APOBEC3B | 0.3348679 |
| TUBB3 | 0.3338096 |
| TMEM176B | 0.3335792 |
| TMEM123 | 0.3335476 |
| FYB | 0.3332403 |
| S100A11 | 0.3328825 |
| KMO | 0.3326720 |
| HPDL | 0.3321936 |
| TLR2 | 0.3320822 |
| RASAL3 | 0.3311095 |
| CHIT1 | 0.3310905 |
| SMCO4 | 0.3309185 |
| PLAC8 | 0.3308013 |
| DDIT4 | 0.3303564 |
| CLIC3 | 0.3300961 |
| CASP1 | 0.3299625 |
| TIMD4 | 0.3295940 |
| MS4A4A | 0.3290770 |
| MRC1 | 0.3290152 |
| SDC1 | 0.3290055 |
| ERP27 | 0.3284690 |
| LY6K | 0.3279954 |
| EN1 | 0.3271552 |
| ADM | 0.3265800 |
| HLA-DOB | 0.3265671 |
| TTLL4 | 0.3261571 |
| ASB2 | 0.3252899 |
| HRASLS | 0.3251010 |
| IL7R | 0.3250536 |
| SLA | 0.3246867 |
| S100A7A | 0.3246426 |
| INPP5D | 0.3245358 |
| APOBEC3G | 0.3242787 |
| MTFR2 | 0.3241859 |
| IL27RA | 0.3240332 |
| JAKMIP1 | 0.3237296 |
| RUNX3 | 0.3230069 |
| PNP | 0.3229697 |
| ELF5 | 0.3227892 |
| AKR1B10 | 0.3225706 |
| CDC20 | 0.3220648 |
| SPOCK2 | 0.3218176 |
| MEI1 | 0.3214948 |
| FCGR3A | 0.3207397 |
| GPR18 | 0.3201833 |
| TNFRSF21 | 0.3200123 |
| LYN | 0.3188189 |
| GMFG | 0.3184065 |
| TEX40 | 0.3182023 |
| HRCT1 | 0.3179452 |
| CTSS | 0.3179144 |
| PSTPIP1 | 0.3172498 |
| SIRPG | 0.3171398 |
| RDH10 | 0.3164552 |
| KRT6B | 0.3159936 |
| GBP2 | 0.3154329 |
| BATF3 | 0.3154180 |
| CD83 | 0.3142457 |
| TM4SF1 | 0.3136857 |
| LILRB4 | 0.3136293 |
| HLA-DQA1 | 0.3134072 |
| PADI2 | 0.3131522 |
| KCNK5 | 0.3125659 |
| GLIPR2 | 0.3124770 |
| MT1G | 0.3120749 |
| SOWAHD | 0.3119446 |
| SRGN | 0.3107929 |
| CBS | 0.3105189 |
| SLC15A3 | 0.3101478 |
| RASD1 | 0.3095007 |
| OASL | 0.3092334 |
| CEACAM1 | 0.3092099 |
| CD69 | 0.3091879 |
| TNFSF14 | 0.3087833 |
| FPR3 | 0.3084919 |
| SH2D1A | 0.3081100 |
| TTK | 0.3079729 |
| ACSL1 | 0.3079438 |
| CLEC10A | 0.3078284 |
| EDN1 | 0.3077297 |
| NFIL3 | 0.3073483 |
| GGH | 0.3069003 |
| EZH2 | 0.3067115 |
| CD274 | 0.3062787 |
| TMEM40 | 0.3062371 |
| CSAG1 | 0.3062208 |
| FAM78A | 0.3062144 |
| MCOLN2 | 0.3060810 |
| FGL2 | 0.3059359 |
| TNFSF10 | 0.3047273 |
| FCER1G | 0.3046051 |
| MLKL | 0.3039551 |
| MYBL2 | 0.3034397 |
| GIMAP4 | 0.3026314 |
| ABCC11 | 0.3024806 |
| CARD17 | 0.3017292 |
| EBI3 | 0.3014245 |
| DENND1C | 0.3009962 |
| LRMP | 0.3006406 |
| EFNA4 | 0.3003508 |
| CCDC71L | 0.3001066 |
| DLGAP5 | 0.2992788 |
| SAMD9L | 0.2990654 |
| LILRA4 | 0.2986833 |
| LAIR2 | 0.2986791 |
| LILRA6 | 0.2983771 |
| GABRE | 0.2978676 |
| SLFN11 | 0.2978589 |
| APOC1 | 0.2976344 |
| RNF144B | 0.2971222 |
| USP18 | 0.2970713 |
| FPR1 | 0.2970508 |
| RNF182 | 0.2969273 |
| CEBPB | 0.2969252 |
| EOMES | 0.2967931 |
| LPXN | 0.2967177 |
| IL18RAP | 0.2965295 |
| LEMD1 | 0.2963437 |
| HENMT1 | 0.2963403 |
| RBP1 | 0.2959975 |
| ART3 | 0.2957586 |
| MED24 | 0.2952076 |
| C5orf20 | 0.2949397 |
| SERPING1 | 0.2948085 |
| BCL2A1 | 0.2946124 |
| FGG | 0.2945368 |
| VAMP5 | 0.2930220 |
| PSMB3 | 0.2924006 |
| EVI2B | 0.2917535 |
| NASP | 0.2915327 |
| PIM1 | 0.2913278 |
| SAA1 | 0.2912399 |
| CDCA5 | 0.2907791 |
| BIN2 | 0.2907713 |
| FERMT3 | 0.2907215 |
| MDK | 0.2904888 |
| SP140 | 0.2900011 |
| RTN4IP1 | 0.2899804 |
| FCGR2B | 0.2897926 |
| PLAUR | 0.2893274 |
| IL1B | 0.2891606 |
| ASCL2 | 0.2887747 |
| MUC15 | 0.2885202 |
| TNFAIP8 | 0.2884781 |
| PERP | 0.2883620 |
| APOL1 | 0.2873394 |
| MNDA | 0.2872490 |
| HOXB13 | 0.2868932 |
| WNT10A | 0.2866097 |
| CD14 | 0.2863904 |
| AIM1 | 0.2860182 |
| SLC6A14 | 0.2851308 |
| ACTBL2 | 0.2850904 |
| KLRC1 | 0.2848506 |
| GZMM | 0.2845714 |
| MCM10 | 0.2843987 |
| PRKCB | 0.2839270 |
| IL2RA | 0.2838922 |
| CD37 | 0.2835305 |
| DLK1 | 0.2834297 |
| PTAFR | 0.2833812 |
| CXCR4 | 0.2832697 |
| IGSF9 | 0.2831386 |
| CASP5 | 0.2830501 |
| FCGR3B | 0.2826579 |
| C1S | 0.2822521 |
| SCPEP1 | 0.2820845 |
| FAM20A | 0.2818186 |
| PVRL4 | 0.2811202 |
| CASP4 | 0.2810390 |
| TNFRSF4 | 0.2799614 |
| BCL11A | 0.2796252 |
| GPR119 | 0.2795574 |
| SLC35F3 | 0.2795324 |
| TRPV2 | 0.2794075 |
| SPN | 0.2788463 |
| KRT5 | 0.2786728 |
| IL15 | 0.2776723 |
| DEK | 0.2772090 |
| UBE2J1 | 0.2766578 |
| HOMER3 | 0.2765935 |
| APOBEC3A | 0.2765601 |
| GTSF1 | 0.2761960 |
| RGS1 | 0.2761676 |
| CYBA | 0.2760486 |
| ADAM8 | 0.2758442 |
| TRIM27 | 0.2750996 |
| CD68 | 0.2740734 |
| NCF4 | 0.2740548 |
| GLRX | 0.2740033 |
| PAPSS2 | 0.2739074 |
| BLK | 0.2737889 |
| SPAG4 | 0.2737731 |
| GPT2 | 0.2737313 |
| NCOA7 | 0.2736693 |
| MPHOSPH6 | 0.2735288 |
| KRT14 | 0.2734219 |
| EPSTI1 | 0.2730863 |
| STRA8 | 0.2728606 |
| IRF8 | 0.2728150 |
| LST1 | 0.2727630 |
| ZNF750 | 0.2725998 |
| GMPS | 0.2724366 |
| ITGB6 | 0.2722316 |
| CDT1 | 0.2721460 |
| PTGER4 | 0.2716664 |
| IFIH1 | 0.2716061 |
| TNFAIP8L2 | 0.2714088 |
| CD40 | 0.2713868 |
| VPREB3 | 0.2711479 |
| RAC2 | 0.2707725 |
| C1orf162 | 0.2701723 |
| B2M | 0.2695452 |
| EDN2 | 0.2686926 |
| ARHGAP25 | 0.2683757 |
| DERL3 | 0.2681451 |
| ODC1 | 0.2676733 |
| IL18 | 0.2675009 |
| CHST2 | 0.2674359 |
| CIB2 | 0.2673720 |
| TRAF1 | 0.2671974 |
| LAIR1 | 0.2671663 |
| GPR84 | 0.2671494 |
| PSMB8 | 0.2668847 |
| APOL6 | 0.2659891 |
| GIMAP6 | 0.2659628 |
| CEP55 | 0.2657876 |
| FABP6 | 0.2657636 |
| P2RY14 | 0.2655481 |
| CA9 | 0.2652431 |
| MPZL2 | 0.2649507 |
| PLAU | 0.2647856 |
| BUB1 | 0.2647401 |
| TMEM176A | 0.2647296 |
| GGTLC1 | 0.2646639 |
| SLC7A5 | 0.2646178 |
| LBP | 0.2646110 |
| STK17B | 0.2641863 |
| TLR1 | 0.2639773 |
| CLEC4A | 0.2635176 |
| TRAT1 | 0.2634889 |
| PTCHD1 | 0.2631504 |
| TCN2 | 0.2628109 |
| XAGE2 | 0.2625736 |
| MAGEA6 | 0.2624096 |
| DUSP6 | 0.2623371 |
| CTSL | 0.2623152 |
| PTPRK | 0.2622772 |
| NR1H3 | 0.2622502 |
| IFI16 | 0.2621794 |
| RCAN1 | 0.2619987 |
| TYROBP | 0.2615134 |
| NFKBIE | 0.2607845 |
| TNF | 0.2606733 |
| ARL4C | 0.2604614 |
| NDC80 | 0.2603294 |
| UNC13D | 0.2602604 |
| CD82 | 0.2598229 |
| MCM5 | 0.2596061 |
| LILRB1 | 0.2595301 |
| RASGRP2 | 0.2590092 |
| HCAR3 | 0.2587788 |
| LGALS9C | 0.2587538 |
| BTLA | 0.2586696 |
| TIAM2 | 0.2586371 |
| CHEK1 | 0.2585259 |
| SPAG5 | 0.2583122 |
| RNASE6 | 0.2579868 |
| SFT2D2 | 0.2579393 |
| MCM2 | 0.2579031 |
| RASAL1 | 0.2576769 |
| CXorf65 | 0.2572032 |
| SOX10 | 0.2571759 |
| C3 | 0.2571521 |
| RPL39L | 0.2570114 |
| KLRC4 | 0.2569303 |
| GPC2 | 0.2567826 |
| KIFC1 | 0.2566630 |
| EGR2 | 0.2565759 |
| FCN1 | 0.2564483 |
| NUDT5 | 0.2563911 |
| CDC42EP1 | 0.2562377 |
| CD8B | 0.2561488 |
| TOX2 | 0.2557923 |
| OSM | 0.2557474 |
| HTRA4 | 0.2555452 |
| TMSB10 | 0.2555098 |
| MYO1G | 0.2554445 |
| AIF1L | 0.2550246 |
| IGSF6 | 0.2548291 |
| SAMSN1 | 0.2542061 |
| ALOX5 | 0.2539652 |
| UGT2B7 | 0.2539117 |
| HERPUD1 | 0.2536291 |
| CDK1 | 0.2535621 |
| ITM2A | 0.2535055 |
| NMI | 0.2534456 |
| PRODH | 0.2530307 |
| TAGLN2 | 0.2530215 |
| FAM83D | 0.2530066 |
| GIMAP1 | 0.2529853 |
| MTHFD2 | 0.2527677 |
| LSR | 0.2525971 |
| SELPLG | 0.2517282 |
| TTC22 | 0.2517102 |
| FAM131C | 0.2514215 |
| LILRB5 | 0.2514021 |
| ALOX5AP | 0.2513838 |
| PLEKHO1 | 0.2507497 |
| CBR3 | 0.2505917 |
| SLC5A1 | 0.2504134 |
| CDCA2 | 0.2502904 |
| DOK2 | 0.2502479 |
| MS4A1 | 0.2499092 |
| TRIM22 | 0.2497330 |
| GCNT1 | 0.2496460 |
| SLC1A3 | 0.2493867 |
| PTTG2 | 0.2491699 |
| APOL2 | 0.2488898 |
| ALDH2 | 0.2485743 |
| C15orf39 | 0.2480203 |
| EMILIN2 | 0.2477787 |
| HCK | 0.2477664 |
| ITK | 0.2476344 |
| TLE1 | 0.2474939 |
| ASNS | 0.2471902 |
| FAM64A | 0.2469241 |
| SLC16A3 | 0.2468352 |
| MFNG | 0.2468150 |
| PRAME | 0.2466880 |
| ICAM2 | 0.2466760 |
| PLBD1 | 0.2456957 |
| LGALS7 | 0.2452980 |
| RARRES2 | 0.2449705 |
| LBR | 0.2448757 |
| PDSS1 | 0.2448155 |
| MOXD1 | 0.2447618 |
| CYB5R2 | 0.2442278 |
| CSTB | 0.2438548 |
| CTSH | 0.2436320 |
| PPP1R1A | 0.2431661 |
| NFE2L3 | 0.2431595 |
| RAB33A | 0.2430728 |
| TTYH3 | 0.2425826 |
| FAT1 | 0.2425504 |
| S100A2 | 0.2424283 |
| C10orf54 | 0.2423837 |
| SSR4 | 0.2423120 |
| MS4A6A | 0.2421174 |
| CPAMD8 | 0.2419306 |
| KLRC2 | 0.2418405 |
| CD72 | 0.2417616 |
| NUF2 | 0.2415275 |
| MSL1 | 0.2414421 |
| MGAT4A | 0.2412952 |
| HMGB3 | 0.2410098 |
| MCM6 | 0.2409575 |
| PLEKHO2 | 0.2408670 |
| H2AFY2 | 0.2406550 |
| MSN | 0.2404700 |
| CIITA | 0.2403075 |
| LAT | 0.2400396 |
| KRT73 | 0.2398083 |
| NFIB | 0.2395913 |
| SECTM1 | 0.2395502 |
| ICAM4 | 0.2394730 |
| FANCE | 0.2393615 |
| AMY1C | 0.2393537 |
| SAPCD2 | 0.2392637 |
| JARID2 | 0.2389864 |
| IL15RA | 0.2388257 |
| ST14 | 0.2387687 |
| UCK2 | 0.2383925 |
| BMP6 | 0.2376774 |
| IL18BP | 0.2376063 |
| BARX1 | 0.2370860 |
| PRF1 | 0.2370552 |
| ACSL5 | 0.2370468 |
| FGR | 0.2369665 |
| APOBEC3C | 0.2368647 |
| HERC5 | 0.2366315 |
| B4GALT5 | 0.2365704 |
| CCDC109B | 0.2360993 |
| KCNN3 | 0.2359154 |
| CTLA4 | 0.2355969 |
| QPRT | 0.2354017 |
| DOK3 | 0.2352090 |
| CCR1 | 0.2350548 |
| PTTG1 | 0.2349757 |
| WIPF1 | 0.2347870 |
| DONSON | 0.2345880 |
| IL22RA2 | 0.2345555 |
| LYPD5 | 0.2343168 |
| AOAH | 0.2341223 |
| CDCA8 | 0.2339853 |
| HMGA1 | 0.2333239 |
| CX3CL1 | 0.2331407 |
| TNIP3 | 0.2330665 |
| UBE2L6 | 0.2328942 |
| EMP3 | 0.2328628 |
| GRK6 | 0.2322082 |
| TAGAP | 0.2321754 |
| S100A6 | 0.2318177 |
| BID | 0.2318072 |
| PNMA5 | 0.2317757 |
| UGT8 | 0.2317172 |
| LRRC25 | 0.2316968 |
| TPX2 | 0.2312689 |
| OR10H2 | 0.2310212 |
| BTN3A2 | 0.2309002 |
| ZBTB32 | 0.2307430 |
| FUOM | 0.2306604 |
| LY75 | 0.2304400 |
| EXO1 | 0.2302479 |
| MAP3K5 | 0.2300455 |
| COL6A6 | 0.2298566 |
| LDHC | 0.2298248 |
| NPL | 0.2291186 |
| ARNTL2 | 0.2289444 |
| SLC4A11 | 0.2289245 |
| HJURP | 0.2288151 |
| TIGD2 | 0.2287715 |
| PFN1 | 0.2287468 |
| VOPP1 | 0.2287031 |
| CMKLR1 | 0.2286870 |
| POMC | 0.2286659 |
| ATP6V0A4 | 0.2286208 |
| C21orf91 | 0.2284445 |
| CHRNA5 | 0.2280494 |
| SCRG1 | 0.2277398 |
| CAPG | 0.2276977 |
| ABTB2 | 0.2273068 |
| FXYD5 | 0.2272182 |
| DHTKD1 | 0.2271775 |
| MCM4 | 0.2269169 |
| PTK7 | 0.2264044 |
| PTPLA | 0.2263033 |
| MT1H | 0.2262357 |
| TRIM2 | 0.2261907 |
| LDHB | 0.2261397 |
| BATF | 0.2261269 |
| EPHB3 | 0.2261085 |
| PPP1R16B | 0.2260035 |
| CREB3L2 | 0.2257948 |
| RSAD2 | 0.2255405 |
| TLR8 | 0.2252358 |
| HN1 | 0.2252063 |
| SKA3 | 0.2248981 |
| SLURP1 | 0.2247055 |
| GRIN3A | 0.2246387 |
| CSTA | 0.2243711 |
| KIF20A | 0.2241090 |
| BORA | 0.2240952 |
| ANLN | 0.2238933 |
| HLA-DMB | 0.2236320 |
| FOXM1 | 0.2235886 |
| TFEC | 0.2232172 |
| GMNN | 0.2231497 |
| CMTM7 | 0.2230881 |
| DUSP2 | 0.2228985 |
| TNFRSF9 | 0.2228626 |
| CDC25B | 0.2228419 |
| MED1 | 0.2227271 |
| NEK6 | 0.2225549 |
| KIAA0020 | 0.2225540 |
| ITGAL | 0.2221800 |
| S100B | 0.2221319 |
| CCNA2 | 0.2217452 |
| ADA | 0.2217439 |
| TMPRSS13 | 0.2215812 |
| IFI44L | 0.2214275 |
| ARPC1B | 0.2213373 |
| ITGB2 | 0.2212815 |
| EML4 | 0.2212674 |
| CLIC4 | 0.2212568 |
| ITGAM | 0.2210836 |
| CXCR5 | 0.2208082 |
| PXDC1 | 0.2203872 |
| BLM | 0.2203223 |
| GMDS | 0.2202288 |
| GTSE1 | 0.2198739 |
| ACOT9 | 0.2197700 |
| UBE2C | 0.2196178 |
| CRTAM | 0.2194581 |
| BTN3A3 | 0.2193518 |
| IGFL2 | 0.2193374 |
| SLC38A5 | 0.2189527 |
| LGMN | 0.2189185 |
| CPNE2 | 0.2188168 |
| TUBB | 0.2183287 |
| RHBDF2 | 0.2179915 |
| ONECUT2 | 0.2178550 |
| PSMB10 | 0.2177993 |
| PDE4B | 0.2173907 |
| CEACAM6 | 0.2171315 |
| RTP4 | 0.2170819 |
| FA2H | 0.2166337 |
| ACTR3 | 0.2164539 |
| LAP3 | 0.2164424 |
| SEPT1 | 0.2161095 |
| TNFAIP3 | 0.2157542 |
| CASC3 | 0.2157068 |
| SYTL3 | 0.2156283 |
| GFI1 | 0.2155283 |
| STEAP3 | 0.2154726 |
| CD7 | 0.2154517 |
| TCF7L1 | 0.2151616 |
| RGL1 | 0.2151383 |
| ENO1 | 0.2150694 |
| CCL21 | 0.2149875 |
| RFC4 | 0.2148063 |
| TOP2A | 0.2143848 |
| RAB42 | 0.2141133 |
| LIMK2 | 0.2140889 |
| SYT8 | 0.2140642 |
| PLIN2 | 0.2140071 |
| BFSP2 | 0.2137494 |
| TNFAIP2 | 0.2134869 |
| MND1 | 0.2134311 |
| EDARADD | 0.2133396 |
| PLEKHF1 | 0.2132457 |
| COMT | 0.2130010 |
| GIMAP2 | 0.2129182 |
| IFNGR1 | 0.2127569 |
| PTPRC | 0.2127360 |
| CST7 | 0.2123609 |
| KLK10 | 0.2123482 |
| RCSD1 | 0.2120669 |
| TREM1 | 0.2118577 |
| MYO1F | 0.2117906 |
| C16orf54 | 0.2117777 |
| OAS2 | 0.2115711 |
| CTSZ | 0.2114478 |
| SH2B2 | 0.2112710 |
| PPFIBP2 | 0.2109429 |
| TUBA4A | 0.2107942 |
| MIA | 0.2106022 |
| TEX10 | 0.2102475 |
| C1R | 0.2102351 |
| GPR19 | 0.2102198 |
| MFSD2A | 0.2101989 |
| NAPSA | 0.2097472 |
| MX1 | 0.2096299 |
| VSIG4 | 0.2094077 |
| ARHGDIB | 0.2093141 |
| FNDC3B | 0.2090722 |
| FAM171A1 | 0.2088208 |
| LY96 | 0.2085469 |
| APBB1IP | 0.2085090 |
| SRPK1 | 0.2084763 |
| TMEM132A | 0.2084207 |
| GGTLC2 | 0.2083411 |
| DHCR7 | 0.2082520 |
| TOR4A | 0.2082467 |
| APOBEC3F | 0.2081985 |
| BCL11B | 0.2080399 |
| DHRS9 | 0.2079046 |
| UPP1 | 0.2078803 |
| AURKA | 0.2072781 |
| HLA-G | 0.2068141 |
| IFRD1 | 0.2067037 |
| TYMS | 0.2066982 |
| AGAP2 | 0.2066147 |
| PPP1R14B | 0.2064535 |
| PPP1R18 | 0.2063882 |
| CPVL | 0.2061314 |
| BCL2L14 | 0.2058771 |
| SPNS2 | 0.2057408 |
| IKZF1 | 0.2056981 |
| SUV39H2 | 0.2056192 |
| TES | 0.2052265 |
| SLC31A2 | 0.2051712 |
| FMNL2 | 0.2051596 |
| MAGEA2B | 0.2050957 |
| ARHGAP30 | 0.2049382 |
| TEP1 | 0.2048092 |
| BTK | 0.2048081 |
| PLCH1 | 0.2043488 |
| SLC35F2 | 0.2041427 |
| RPL22L1 | 0.2041000 |
| MPEG1 | 0.2040056 |
| XDH | 0.2039823 |
| RPP40 | 0.2037237 |
| CRYM | 0.2034793 |
| APOE | 0.2034012 |
| CD44 | 0.2033534 |
| PSAP | 0.2033494 |
| MCM3 | 0.2033116 |
| SREBF2 | 0.2032137 |
| HR | 0.2030406 |
| FLI1 | 0.2028743 |
| E2F3 | 0.2027099 |
| SPIB | 0.2025364 |
| SLC31A1 | 0.2023537 |
| ASGR1 | 0.2020491 |
| NCKAP1L | 0.2020400 |
| ADAM19 | 0.2019299 |
| ST8SIA1 | 0.2018277 |
| OR7E24 | 0.2017133 |
| CFLAR | 0.2016618 |
| PRDM1 | 0.2016323 |
| CFP | 0.2015924 |
| CORO1C | 0.2015619 |
| KPNA2 | 0.2014670 |
| RNASEH1 | 0.2012733 |
| MGAT1 | 0.2009272 |
| S100A4 | 0.2008037 |
| UCHL3 | 0.2001364 |
| CECR1 | 0.2001360 |
| MAGED4B | 0.1998607 |
| MAP4K1 | 0.1998200 |
| ACP5 | 0.1998045 |
| PRDM13 | 0.1997637 |
| NABP1 | 0.1996954 |
| ICAM3 | 0.1996800 |
| SAMD3 | 0.1996084 |
| CRELD2 | 0.1993702 |
| HMGN3 | 0.1990372 |
| ADAMTS4 | 0.1988297 |
| MB21D1 | 0.1987846 |
| CHRM1 | 0.1986887 |
| FCRL2 | 0.1985999 |
| TNNI2 | 0.1985299 |
| RBM38 | 0.1984388 |
| LMAN1 | 0.1983776 |
| CTSW | 0.1983288 |
| C3AR1 | 0.1981036 |
| ZBED6CL | 0.1980887 |
| MT2A | 0.1980797 |
| ARAP2 | 0.1979757 |
| INA | 0.1979110 |
| KIF4A | 0.1978634 |
| KLRD1 | 0.1973765 |
| SLC2A5 | 0.1973657 |
| PNRC1 | 0.1972077 |
| SRPK3 | 0.1970343 |
| DNMT3B | 0.1968074 |
| RMI2 | 0.1967477 |
| FEN1 | 0.1967218 |
| ADCY7 | 0.1966948 |
| FAIM2 | 0.1966788 |
| ABI3 | 0.1965013 |
| SPTSSA | 0.1964555 |
| LGALS9 | 0.1964344 |
| ANP32E | 0.1963146 |
| EMR2 | 0.1962055 |
| NARF | 0.1961946 |
| H2AFX | 0.1959895 |
| RANGAP1 | 0.1959272 |
| SELL | 0.1958467 |
| ASRGL1 | 0.1956290 |
| CD300LF | 0.1954971 |
| SCEL | 0.1954485 |
| CKS1B | 0.1954206 |
| CCNB2 | 0.1953528 |
| FCN3 | 0.1953433 |
| FDPS | 0.1951138 |
| HORMAD1 | 0.1949762 |
| B4GALT3 | 0.1949641 |
| SGK1 | 0.1949193 |
| FYN | 0.1949077 |
| ERCC6L | 0.1948421 |
| HVCN1 | 0.1945237 |
| PAX7 | 0.1945193 |
| MGST1 | 0.1944365 |
| MAGEA12 | 0.1940823 |
| TMPRSS4 | 0.1940280 |
| FNBP1 | 0.1939066 |
| RELB | 0.1938573 |
| JAK3 | 0.1937519 |
| PCP4 | 0.1937024 |
| PARP12 | 0.1936056 |
| RFTN1 | 0.1934619 |
| KRT15 | 0.1930593 |
| FMO1 | 0.1929588 |
| GCH1 | 0.1929170 |
| PREP | 0.1923993 |
| APOC2 | 0.1921960 |
| DUSP4 | 0.1918397 |
| TFAP2B | 0.1918383 |
| OR8B8 | 0.1914336 |
| CARD9 | 0.1913863 |
| ZFP36 | 0.1913173 |
| FCGR2A | 0.1911356 |
| FBN3 | 0.1908350 |
| TRIM69 | 0.1903795 |
| IFI44 | 0.1902471 |
| CNN2 | 0.1901540 |
| SRSF12 | 0.1900238 |
| IFIT3 | 0.1896875 |
| MCCC1 | 0.1896262 |
| HAVCR2 | 0.1895596 |
| SLC15A1 | 0.1894503 |
| SCGB1A1 | 0.1893938 |
| LIME1 | 0.1893349 |
| CTSB | 0.1891370 |
| NAGK | 0.1890303 |
| CDKN3 | 0.1890199 |
| TPM4 | 0.1889158 |
| RTN4R | 0.1888484 |
| FAM92B | 0.1887716 |
| OAS1 | 0.1887285 |
| VPS37B | 0.1886977 |
| GPR56 | 0.1882571 |
| GNGT2 | 0.1882316 |
| WNT2 | 0.1882174 |
| AIF1 | 0.1882041 |
| OGFRL1 | 0.1881228 |
| BHLHA15 | 0.1878360 |
| CCK | 0.1878070 |
| IFNAR2 | 0.1875092 |
| CDCA3 | 0.1872931 |
| FAS | 0.1872840 |
| FAM101A | 0.1872370 |
| CCL20 | 0.1869349 |
| NLRC5 | 0.1864654 |
| MX2 | 0.1863309 |
| KCNK12 | 0.1862952 |
| BTN2A2 | 0.1861382 |
| ABCC3 | 0.1860969 |
| AKR1A1 | 0.1860019 |
| CST6 | 0.1858060 |
| USB1 | 0.1857876 |
| DUSP10 | 0.1857596 |
| GPRC5B | 0.1856108 |
| PGD | 0.1854395 |
| CLPTM1L | 0.1851281 |
| SPNS3 | 0.1850428 |
| KIF11 | 0.1850028 |
| CASP10 | 0.1849993 |
| DYSF | 0.1849423 |
| SERPINB9 | 0.1847968 |
| SUSD2 | 0.1846726 |
| MSANTD3 | 0.1845203 |
| ARPC5L | 0.1844105 |
| ZFP57 | 0.1843003 |
| HECA | 0.1842893 |
| TSPAN33 | 0.1842744 |
| GLDC | 0.1841703 |
| NDRG1 | 0.1840900 |
| RRAGD | 0.1839404 |
| FBLN2 | 0.1839132 |
| PTPN22 | 0.1837751 |
| BLNK | 0.1832722 |
| EVX1 | 0.1831301 |
| IL7 | 0.1830226 |
| USP6NL | 0.1829631 |
| SLC43A3 | 0.1829520 |
| CYTH1 | 0.1829036 |
| PEG10 | 0.1828049 |
| COL27A1 | 0.1827764 |
| IL17RE | 0.1826129 |
| QPCT | 0.1825831 |
| CDC123 | 0.1825819 |
| MAPK1 | 0.1825342 |
| NFAM1 | 0.1821385 |
| GMIP | 0.1815636 |
| SLC6A16 | 0.1814043 |
| PAK1IP1 | 0.1812002 |
| CATSPERB | 0.1808525 |
| RCN1 | 0.1807740 |
| RNASE1 | 0.1804552 |
| HK3 | 0.1803873 |
| GIMAP8 | 0.1803294 |
| TSPAN6 | 0.1802984 |
| DSC2 | 0.1799861 |
| SLCO2B1 | 0.1797492 |
| CHAF1B | 0.1795567 |
| TEX30 | 0.1795366 |
| BAK1 | 0.1794468 |
| STMN1 | 0.1793339 |
| ENPP3 | 0.1793032 |
| CXCL16 | 0.1792657 |
| SFRP1 | 0.1789670 |
| SAT1 | 0.1789540 |
| PGM1 | 0.1788025 |
| TCF3 | 0.1787206 |
| CAMK1D | 0.1786890 |
| SEPHS1 | 0.1786715 |
| BTG3 | 0.1786012 |
| SEC11C | 0.1784123 |
| CCL11 | 0.1783557 |
| FBXO6 | 0.1782366 |
| SHCBP1 | 0.1781059 |
| FKBP5 | 0.1781007 |
| ALYREF | 0.1780630 |
| HLA-DOA | 0.1776361 |
| ARHGAP15 | 0.1776053 |
| PIF1 | 0.1775725 |
| SRD5A1 | 0.1775143 |
| E2F1 | 0.1773362 |
| MTHFD1L | 0.1772897 |
| PRSS16 | 0.1772877 |
| CSF1R | 0.1772796 |
| RHBDL1 | 0.1771655 |
| IL17RA | 0.1767311 |
| BIRC5 | 0.1767228 |
| ARFGAP3 | 0.1766486 |
| CHST6 | 0.1765986 |
| RIPK2 | 0.1765174 |
| GGT1 | 0.1764146 |
| ENPP2 | 0.1763618 |
| MARCKS | 0.1761781 |
| ABLIM1 | 0.1760381 |
| TGM2 | 0.1759673 |
| XAF1 | 0.1759631 |
| ARHGAP4 | 0.1758815 |
| VEGFA | 0.1757247 |
| VLDLR | 0.1756995 |
| TMIGD2 | 0.1756864 |
| ADORA2B | 0.1756057 |
| SLC41A2 | 0.1755209 |
| OSTF1 | 0.1755166 |
| DBI | 0.1755091 |
| TOMM40L | 0.1754819 |
| NETO2 | 0.1754392 |
| TMEM51 | 0.1753627 |
| CD163L1 | 0.1753057 |
| LRRK1 | 0.1752734 |
| ATP11C | 0.1752418 |
| RGMA | 0.1751434 |
| PHEX | 0.1751429 |
| FBXO32 | 0.1750267 |
| CXorf21 | 0.1750021 |
| PRDX4 | 0.1748982 |
| CRISP2 | 0.1747032 |
| RPUSD3 | 0.1746766 |
| RRAS2 | 0.1744646 |
| RAD54L | 0.1742665 |
| RRM2 | 0.1742015 |
| SLC18B1 | 0.1741710 |
| PITX1 | 0.1741686 |
| UBE2E3 | 0.1741592 |
| CCNC | 0.1740084 |
| CLEC4D | 0.1738434 |
| PDCD5 | 0.1738143 |
| ELFN1 | 0.1737370 |
| GNB4 | 0.1735448 |
| PSMG1 | 0.1735050 |
| MSLN | 0.1731368 |
| FTL | 0.1731178 |
| TMEM79 | 0.1728899 |
| SLC36A4 | 0.1728298 |
| MT1B | 0.1727810 |
| IGF2R | 0.1727103 |
| PRKD3 | 0.1727098 |
| HDAC2 | 0.1725771 |
| MYO18A | 0.1724941 |
| SLC5A6 | 0.1724784 |
| TDP1 | 0.1724485 |
| NXPH4 | 0.1721701 |
| CELF4 | 0.1721580 |
| SOX8 | 0.1719188 |
| RIPK4 | 0.1719034 |
| TIMM8A | 0.1718096 |
| TSPO | 0.1717171 |
| IL6 | 0.1716556 |
| CTPS1 | 0.1713999 |
| NUP155 | 0.1713212 |
| PRKCQ | 0.1711498 |
| C2CD4A | 0.1711169 |
| IDI1 | 0.1711134 |
| CES1 | 0.1710714 |
| LY6E | 0.1709013 |
| ZFP36L2 | 0.1708896 |
| RGS10 | 0.1705429 |
| GPR65 | 0.1705147 |
| PPA1 | 0.1704610 |
| PIK3CG | 0.1704395 |
| CCND2 | 0.1703930 |
| CD47 | 0.1703601 |
| SCGB3A1 | 0.1702515 |
| EVI2A | 0.1702075 |
| ARRB2 | 0.1699513 |
| LMNB1 | 0.1694776 |
| GGCT | 0.1692737 |
| ALOX15B | 0.1689973 |
| SLC45A4 | 0.1689476 |
| STK38 | 0.1688315 |
| CYP27A1 | 0.1688255 |
| UBE2T | 0.1687750 |
| E2F2 | 0.1687106 |
| ASPM | 0.1684570 |
| AMD1 | 0.1681852 |
| SDR42E1 | 0.1681466 |
| MVD | 0.1679897 |
| CR2 | 0.1676326 |
| LPIN1 | 0.1676232 |
| SNX3 | 0.1675943 |
| CKAP4 | 0.1675647 |
| TTC7A | 0.1675129 |
| MARCH1 | 0.1674318 |
| MMS22L | 0.1674221 |
| PFDN2 | 0.1673014 |
| SMPDL3B | 0.1672932 |
| ORC6 | 0.1671745 |
| LHX2 | 0.1670992 |
| ATL3 | 0.1670201 |
| EHD1 | 0.1669308 |
| RELT | 0.1669234 |
| SLC2A6 | 0.1669209 |
| B3GAT1 | 0.1668070 |
| STX11 | 0.1665118 |
| CEBPA | 0.1665020 |
| GPR132 | 0.1663726 |
| MYD88 | 0.1663641 |
| CYB561A3 | 0.1662875 |
| ITGA6 | 0.1661446 |
| CCNE2 | 0.1659319 |
| TUBB6 | 0.1657798 |
| IL6R | 0.1657634 |
| C1orf112 | 0.1657126 |
| TPST2 | 0.1656994 |
| TNFSF13 | 0.1656541 |
| DDOST | 0.1656083 |
| DDC | 0.1656043 |
| TGM1 | 0.1655064 |
| NCAPD2 | 0.1652577 |
| CYTH4 | 0.1650591 |
| NUP93 | 0.1647177 |
| CHN1 | 0.1647115 |
| JAK2 | 0.1645559 |
| PDXK | 0.1645510 |
| ACAT2 | 0.1645099 |
| NUS1 | 0.1645068 |
| CKAP2L | 0.1645041 |
| RGS18 | 0.1644203 |
| BYSL | 0.1640587 |
| PDIA5 | 0.1640273 |
| AKR1B1 | 0.1640145 |
| CARD6 | 0.1639615 |
| CLECL1 | 0.1637762 |
| KRT24 | 0.1637498 |
| RRP36 | 0.1635874 |
| MAGED1 | 0.1635064 |
| FAM111B | 0.1632796 |
| TINAGL1 | 0.1632417 |
| NAMPT | 0.1631711 |
| FBLN5 | 0.1631120 |
| KRT4 | 0.1631066 |
| GSDMC | 0.1630670 |
| DESI1 | 0.1630651 |
| RAB9A | 0.1630502 |
| PDLIM1 | 0.1626958 |
| GPSM2 | 0.1626496 |
| ZC3H12A | 0.1625030 |
| ST6GALNAC5 | 0.1624849 |
| DDX26B | 0.1624798 |
| UBASH3A | 0.1623562 |
| STAT5A | 0.1622519 |
| LHFPL2 | 0.1622229 |
| ARL5B | 0.1620678 |
| CFH | 0.1618123 |
| PHF19 | 0.1618072 |
| ILF2 | 0.1617532 |
| KDELR3 | 0.1617431 |
| CHML | 0.1617063 |
| ABCF1 | 0.1615867 |
| ZNF607 | 0.1614977 |
| PLSCR1 | 0.1614650 |
| CSF2RA | 0.1614487 |
| FBXO5 | 0.1614166 |
| SMOC1 | 0.1614027 |
| SLC5A11 | 0.1613930 |
| RGS20 | 0.1613601 |
| DUSP22 | 0.1612929 |
| SMARCD2 | 0.1611141 |
| IL34 | 0.1610186 |
| ARHGAP27 | 0.1610077 |
| APOOL | 0.1605000 |
| RFC2 | 0.1603790 |
| GFRA3 | 0.1602118 |
| CFHR3 | 0.1600254 |
| CSK | 0.1600034 |
| FANCA | 0.1599488 |
| ERO1L | 0.1599316 |
| MCUR1 | 0.1599299 |
| PELI1 | 0.1598440 |
| CD28 | 0.1597226 |
| AADAT | 0.1596430 |
| DNAJB11 | 0.1594925 |
| PARP8 | 0.1593340 |
| SYNM | 0.1593110 |
| RASGEF1A | 0.1592670 |
| GLYATL1 | 0.1592657 |
| TARS | 0.1592126 |
| SYNCRIP | 0.1590320 |
| DPT | 0.1589707 |
| SNX10 | 0.1588538 |
| NRBF2 | 0.1588048 |
| PTCRA | 0.1585501 |
| KARS | 0.1585329 |
| OLIG1 | 0.1585007 |
| BST2 | 0.1583544 |
| TRMU | 0.1583296 |
| CHAC2 | 0.1579444 |
| C11orf86 | 0.1578436 |
| AKAP7 | 0.1578159 |
| CD4 | 0.1577723 |
| HMMR | 0.1577537 |
| PRRX2 | 0.1575873 |
| TXNDC11 | 0.1574591 |
| PDZD2 | 0.1574002 |
| MCM7 | 0.1571852 |
| IFNL2 | 0.1570438 |
| ADAM15 | 0.1569729 |
| LRRN1 | 0.1568918 |
| F11R | 0.1567740 |
| CDK12 | 0.1567259 |
| RIOK1 | 0.1566591 |
| ADTRP | 0.1565380 |
| RRBP1 | 0.1563747 |
| TBX10 | 0.1562683 |
| CYP27B1 | 0.1561018 |
| CFL1 | 0.1560783 |
| NCEH1 | 0.1560048 |
| TMSB4X | 0.1559258 |
| TICRR | 0.1559186 |
| TNFRSF25 | 0.1558003 |
| PDPN | 0.1557246 |
| TMEM38A | 0.1556842 |
| TMEM65 | 0.1556401 |
| HIVEP2 | 0.1555960 |
| CPM | 0.1555750 |
| BACE2 | 0.1553887 |
| STAC | 0.1552248 |
| MORC4 | 0.1552050 |
| TMEM158 | 0.1550705 |
| APOL3 | 0.1550522 |
| SEPT6 | 0.1549965 |
| SLC25A19 | 0.1549288 |
| C19orf38 | 0.1548101 |
| PSME2 | 0.1546613 |
| GM2A | 0.1546526 |
| CYP7B1 | 0.1546140 |
| SLC16A1 | 0.1545857 |
| SYNGR4 | 0.1545383 |
| IL23A | 0.1544358 |
| PI3 | 0.1544046 |
| SAMD4A | 0.1543474 |
| RPF2 | 0.1543119 |
| SLC35B1 | 0.1543030 |
| MT1X | 0.1542513 |
| PSMB2 | 0.1541160 |
| MTFP1 | 0.1540245 |
| SDF2L1 | 0.1539457 |
| TMEM171 | 0.1538439 |
| SUPT5H | 0.1537390 |
| CENPE | 0.1536533 |
| SDHA | 0.1536415 |
| PAG1 | 0.1536126 |
| TOR3A | 0.1535327 |
| INSL3 | 0.1533868 |
| CMC2 | 0.1533603 |
| DOCK8 | 0.1533459 |
| TGFBI | 0.1532567 |
| UAP1 | 0.1531852 |
| NRTN | 0.1531800 |
| VGF | 0.1530612 |
| FAM89B | 0.1530514 |
| MFGE8 | 0.1528015 |
| KLRC3 | 0.1527709 |
| LAT2 | 0.1527066 |
| ANKS6 | 0.1525383 |
| CENPF | 0.1524801 |
| PKIA | 0.1524042 |
| RANBP1 | 0.1523531 |
| PAX6 | 0.1522641 |
| RILP | 0.1522420 |
| VARS | 0.1521468 |
| SLC6A2 | 0.1520874 |
| CLDN4 | 0.1519921 |
| SBK1 | 0.1518735 |
| KRT9 | 0.1517724 |
| MCL1 | 0.1516907 |
| TMEM130 | 0.1516555 |
| TBC1D7 | 0.1515711 |
| PABPC3 | 0.1515469 |
| BIN1 | 0.1515057 |
| MALL | 0.1513532 |
| INCENP | 0.1513427 |
| C2CD4B | 0.1512559 |
| DNAJB9 | 0.1511997 |
| RHOG | 0.1507428 |
| LIMS1 | 0.1501774 |
| C10orf10 | 0.1499651 |
| RASSF5 | 0.1499454 |
| RNF19A | 0.1499081 |
| TEAD4 | 0.1498352 |
| BHLHE23 | 0.1497660 |
| IFFO2 | 0.1495894 |
| PHLDA2 | 0.1495826 |
| SPC25 | 0.1495483 |
| DRAM1 | 0.1494188 |
| YBX1 | 0.1493930 |
| C6orf15 | 0.1493454 |
| SIGLEC10 | 0.1492456 |
| TRIM16L | 0.1492434 |
| GTPBP8 | 0.1491972 |
| IL3RA | 0.1491680 |
| PIP5K1B | 0.1491406 |
| USP41 | 0.1490737 |
| ADI1 | 0.1489403 |
| SKP2 | 0.1488934 |
| CCDC50 | 0.1486854 |
| UCP2 | 0.1486702 |
| GTF3C6 | 0.1486285 |
| RNGTT | 0.1485672 |
| LCE1D | 0.1485287 |
| GALM | 0.1484633 |
| ATF4 | 0.1484329 |
| EIF4G1 | 0.1484319 |
| PGM3 | 0.1481817 |
| ANXA1 | 0.1480730 |
| TRABD2A | 0.1479888 |
| PML | 0.1479456 |
| NCK1 | 0.1479382 |
| VIT | 0.1479212 |
| ME1 | 0.1477413 |
| SOAT1 | 0.1475603 |
| CEACAM19 | 0.1474630 |
| VMO1 | 0.1474310 |
| DEPDC1B | 0.1474298 |
| PPP2R2B | 0.1472627 |
| PSME4 | 0.1472347 |
| FAM72D | 0.1472082 |
| NRN1 | 0.1470118 |
| SERPINB8 | 0.1469432 |
| PSPH | 0.1467459 |
| MAN2B1 | 0.1466981 |
| SLC25A5 | 0.1466905 |
| FOLH1 | 0.1466044 |
| TNFRSF13C | 0.1465461 |
| TLR6 | 0.1465069 |
| VPS72 | 0.1461482 |
| SCML4 | 0.1460514 |
| SLC28A3 | 0.1459871 |
| TRPM2 | 0.1458385 |
| BMP7 | 0.1458169 |
| CA13 | 0.1456960 |
| A2ML1 | 0.1456607 |
| FOLR1 | 0.1456027 |
| RPN1 | 0.1455978 |
| ACN9 | 0.1455744 |
| SCD | 0.1454992 |
| TMEM138 | 0.1453388 |
| SAP30 | 0.1452276 |
| DNAJC9 | 0.1451238 |
| ACAP1 | 0.1450404 |
| ETFA | 0.1448763 |
| SUMO3 | 0.1448590 |
| PTPN6 | 0.1447241 |
| SEC61B | 0.1444260 |
| H2AFZ | 0.1443692 |
| ZYX | 0.1442208 |
| CIRH1A | 0.1441483 |
| VNN1 | 0.1441469 |
| TPD52L1 | 0.1441413 |
| HHIPL2 | 0.1440224 |
| RYR1 | 0.1439506 |
| RPS6KA4 | 0.1439465 |
| PDIA6 | 0.1438346 |
| HEPH | 0.1437018 |
| TFDP2 | 0.1436784 |
| ECT2 | 0.1436373 |
| NEUROD2 | 0.1434707 |
| EIF4A1 | 0.1434377 |
| HIST1H2BK | 0.1434078 |
| SNRPB | 0.1432137 |
| KREMEN2 | 0.1430828 |
| RPS6KA3 | 0.1430462 |
| NNMT | 0.1430138 |
| CYB5R4 | 0.1429752 |
| PALM2-AKAP2 | 0.1429414 |
| ITGAX | 0.1427835 |
| NTMT1 | 0.1427714 |
| SMC6 | 0.1427466 |
| SHMT2 | 0.1427301 |
| KLK7 | 0.1427100 |
| BEND3 | 0.1427037 |
| CKS2 | 0.1426605 |
| ITPR3 | 0.1426189 |
| CLIC2 | 0.1425870 |
| CD300A | 0.1425130 |
| RGCC | 0.1425122 |
| ID2 | 0.1424950 |
| CUL1 | 0.1424395 |
| TUBA1C | 0.1424248 |
| LRRK2 | 0.1421191 |
| KCNA3 | 0.1420725 |
| CTAG1A | 0.1420181 |
| S1PR2 | 0.1420010 |
| TTC39B | 0.1419436 |
| MYO10 | 0.1419129 |
| CAP1 | 0.1418096 |
| SLC39A7 | 0.1418017 |
| PLD1 | 0.1417948 |
| TLCD1 | 0.1417507 |
| MAD2L1 | 0.1416935 |
| UGP2 | 0.1416404 |
| MILR1 | 0.1415048 |
| DSCC1 | 0.1413287 |
| EGLN3 | 0.1413113 |
| GPR114 | 0.1411128 |
| ANP32B | 0.1410881 |
| FBL | 0.1409444 |
| VDR | 0.1409207 |
| NCR3 | 0.1407178 |
| KLF5 | 0.1406233 |
| PDP1 | 0.1405963 |
| NT5DC2 | 0.1405637 |
| COLGALT1 | 0.1405521 |
| BPIFB2 | 0.1405242 |
| FAM65B | 0.1405222 |
| FOXL1 | 0.1404583 |
| AKIRIN2 | 0.1402457 |
| ACTB | 0.1402352 |
| CDC42SE1 | 0.1401367 |
| IRF5 | 0.1400244 |
| PPM1G | 0.1400165 |
| PBX4 | 0.1400151 |
| MRAS | 0.1399854 |
| LZTS3 | 0.1399794 |
| FBXL20 | 0.1398574 |
| NPC2 | 0.1397961 |
| VASN | 0.1397138 |
| KLK6 | 0.1396259 |
| VCP | 0.1395804 |
| PLAGL2 | 0.1395362 |
| TPK1 | 0.1394240 |
| IFI6 | 0.1393989 |
| ACOXL | 0.1393136 |
| COL6A5 | 0.1392092 |
| EIF3K | 0.1390821 |
| ACTR3B | 0.1390167 |
| PITPNB | 0.1389816 |
| NTN1 | 0.1389511 |
| RGS16 | 0.1389104 |
| WDR4 | 0.1387904 |
| TRIB1 | 0.1387588 |
| NACC2 | 0.1385116 |
| RHEBL1 | 0.1385019 |
| MAPK4 | 0.1384698 |
| SUN2 | 0.1384238 |
| PSMD11 | 0.1383906 |
| IL16 | 0.1383446 |
| KLRK1 | 0.1382477 |
| GARS | 0.1382187 |
| S100A12 | 0.1382011 |
| PPIB | 0.1381978 |
| NUP50 | 0.1379608 |
| IL10 | 0.1379607 |
| DGAT2 | 0.1379554 |
| LITAF | 0.1377323 |
| CNN3 | 0.1376321 |
| RAB43 | 0.1375370 |
| CDC25A | 0.1374929 |
| BST1 | 0.1374126 |
| C17orf62 | 0.1374013 |
| SLC25A33 | 0.1373963 |
| TAPBPL | 0.1373796 |
| C17orf49 | 0.1373117 |
| PLK1 | 0.1372969 |
| EMB | 0.1372375 |
| IL1R2 | 0.1372305 |
| CWC25 | 0.1371901 |
| TIMM50 | 0.1371608 |
| S100A16 | 0.1371244 |
| AGO2 | 0.1370938 |
| FUT4 | 0.1369697 |
| HAPLN1 | 0.1369236 |
| HMGCS1 | 0.1368517 |
| CENPN | 0.1368164 |
| NOD2 | 0.1367254 |
| COMMD2 | 0.1364406 |
| PFKL | 0.1363745 |
| HPCAL1 | 0.1363224 |
| UFD1L | 0.1361571 |
| TOMM22 | 0.1361097 |
| TRIM47 | 0.1360777 |
| FAM107A | 0.1360500 |
| SAA2 | 0.1359823 |
| C6orf203 | 0.1358592 |
| TUBB2A | 0.1357418 |
| LRRC59 | 0.1355967 |
| KCNMB1 | 0.1355668 |
| BAG2 | 0.1354264 |
| ZC3H12C | 0.1353783 |
| CD84 | 0.1353067 |
| SNAI3 | 0.1352979 |
| AMER1 | 0.1352751 |
| TNFRSF1B | 0.1352236 |
| KRT83 | 0.1351916 |
| RAD51AP1 | 0.1351209 |
| ASPH | 0.1350907 |
| STAT4 | 0.1350818 |
| LRRC8D | 0.1349658 |
| UTS2R | 0.1348536 |
| SERPINF1 | 0.1348057 |
| LRRC8C | 0.1347555 |
| PTMS | 0.1347426 |
| RSU1 | 0.1346815 |
| SLC1A5 | 0.1345979 |
| KIF15 | 0.1345790 |
| SEC14L1 | 0.1345692 |
| IDH1 | 0.1343431 |
| STEAP1 | 0.1343095 |
| STARD4 | 0.1342491 |
| MOB1A | 0.1342360 |
| PCSK9 | 0.1341072 |
| EDEM1 | 0.1340201 |
| PLCB4 | 0.1339874 |
| TWF2 | 0.1339698 |
| LILRA3 | 0.1339221 |
| CD58 | 0.1338138 |
| JOSD1 | 0.1337992 |
| PHOSPHO1 | 0.1337717 |
| FMO2 | 0.1337187 |
| E2F8 | 0.1336791 |
| KANK4 | 0.1336413 |
| FMNL1 | 0.1336407 |
| RAB27A | 0.1335818 |
| FUT7 | 0.1335310 |
| UBAC2 | 0.1334794 |
| CYR61 | 0.1334329 |
| DTX2 | 0.1332811 |
| PACSIN2 | 0.1332681 |
| URI1 | 0.1332676 |
| NFKBIB | 0.1332162 |
| MT1A | 0.1330456 |
| RNF122 | 0.1328798 |
| TIPRL | 0.1327627 |
| UBE2D1 | 0.1327615 |
| KRT6C | 0.1327305 |
| SQRDL | 0.1326733 |
| GLT1D1 | 0.1325226 |
| FCRLA | 0.1324937 |
| PDIA4 | 0.1324644 |
| TP53I3 | 0.1324071 |
| HIF1A | 0.1323721 |
| WAS | 0.1322880 |
| TRADD | 0.1322828 |
| RAB20 | 0.1322526 |
| GDI2 | 0.1322426 |
| NUTF2 | 0.1321920 |
| POR | 0.1320994 |
| YWHAQ | 0.1320904 |
| OSBPL3 | 0.1320599 |
| C7orf49 | 0.1318984 |
| LPAR3 | 0.1318864 |
| RNASET2 | 0.1318108 |
| LCE1A | 0.1318090 |
| NUP153 | 0.1317847 |
| YPEL1 | 0.1315524 |
| HIST2H3A | 0.1315006 |
| IFNGR2 | 0.1314433 |
| NCAPG | 0.1313189 |
| AARS | 0.1312798 |
| ATP6V0A2 | 0.1312685 |
| TMEM139 | 0.1312658 |
| ZW10 | 0.1310872 |
| CCRL2 | 0.1310343 |
| S100A10 | 0.1310085 |
| PHACTR2 | 0.1309593 |
| GALR3 | 0.1308753 |
| DRG1 | 0.1308598 |
| BCL2L12 | 0.1308345 |
| TANK | 0.1308180 |
| SAA4 | 0.1306943 |
| EHF | 0.1306663 |
| SLC10A3 | 0.1305498 |
| VASP | 0.1303666 |
| CDC42SE2 | 0.1302343 |
| TNFRSF6B | 0.1302061 |
| RND3 | 0.1302000 |
| PRKCH | 0.1300572 |
| CDC7 | 0.1300556 |
| NUP205 | 0.1300398 |
| SFT2D1 | 0.1299685 |
| CXADR | 0.1299367 |
| IFIT2 | 0.1297945 |
| ZWINT | 0.1297348 |
| C12orf45 | 0.1296375 |
| CD99 | 0.1295955 |
| SLFN13 | 0.1293988 |
| OR11A1 | 0.1293266 |
| ITPRIP | 0.1293232 |
| PSMD2 | 0.1293164 |
| HAUS8 | 0.1291917 |
| CHEK2 | 0.1291736 |
| ALAS1 | 0.1291130 |
| TRIP13 | 0.1291000 |
| PRLHR | 0.1290782 |
| CAMP | 0.1290748 |
| PABPC1 | 0.1289115 |
| TFDP1 | 0.1288682 |
| PLEKHG1 | 0.1288122 |
| GYPC | 0.1286958 |
| STAG3 | 0.1285330 |
| CBX2 | 0.1285052 |
| DCPS | 0.1284864 |
| SLC35C1 | 0.1284309 |
| CHAC1 | 0.1283806 |
| PTPN2 | 0.1281379 |
| STOX2 | 0.1279923 |
| GPR12 | 0.1279728 |
| HSP90B1 | 0.1279107 |
| ST3GAL5 | 0.1278768 |
| CCNJL | 0.1278242 |
| FAM107B | 0.1277770 |
| FLNA | 0.1277561 |
| CYSLTR1 | 0.1276795 |
| PRELID1 | 0.1276776 |
| KRTAP4-12 | 0.1276726 |
| CLUH | 0.1276110 |
| EHBP1L1 | 0.1275854 |
| MEMO1 | 0.1273966 |
| PLCB2 | 0.1273419 |
| RPN2 | 0.1270960 |
| ZMYND15 | 0.1270555 |
| MYL12A | 0.1270104 |
| C19orf66 | 0.1269284 |
| IL4R | 0.1268829 |
| ATP11A | 0.1268341 |
| ARHGAP22 | 0.1268002 |
| SEC13 | 0.1267199 |
| LMO1 | 0.1266869 |
| CNIH4 | 0.1265494 |
| TPP2 | 0.1264976 |
| UBALD2 | 0.1264353 |
| MRPL11 | 0.1262160 |
| PLEKHG6 | 0.1261304 |
| KRT20 | 0.1260547 |
| NIP7 | 0.1258859 |
| XRCC6 | 0.1258293 |
| SLC43A2 | 0.1257824 |
| IL27 | 0.1257819 |
| C16orf80 | 0.1257022 |
| UQCRFS1 | 0.1256200 |
| MBNL3 | 0.1255906 |
| LGALS3 | 0.1255543 |
| HMBS | 0.1255421 |
| SLC7A1 | 0.1255415 |
| KCNJ2 | 0.1254296 |
| TNFSF4 | 0.1254235 |
| GHSR | 0.1253931 |
| MAD2L2 | 0.1253910 |
| SOD3 | 0.1253863 |
| SLC8A1 | 0.1253526 |
| MRPS12 | 0.1253522 |
| GPM6B | 0.1253364 |
| CREB3L1 | 0.1251903 |
| KCNK1 | 0.1250848 |
| RHCG | 0.1250232 |
| GAS1 | 0.1249459 |
| PDHA1 | 0.1247989 |
| GPNMB | 0.1247211 |
| RRP1B | 0.1246890 |
| SNRPA1 | 0.1243892 |
| SGPP2 | 0.1243623 |
| RTCB | 0.1243272 |
| AURKB | 0.1243037 |
| FAM19A3 | 0.1242658 |
| DSP | 0.1242630 |
| TCF7 | 0.1242364 |
| C2orf72 | 0.1241418 |
| RFWD3 | 0.1241317 |
| DBN1 | 0.1241249 |
| PCDHB11 | 0.1241000 |
| CRLF1 | 0.1240904 |
| FAF1 | 0.1240872 |
| ING1 | 0.1240001 |
| TMC8 | 0.1239693 |
| TMEM86A | 0.1238974 |
| TMEM140 | 0.1238508 |
| SCIMP | 0.1238290 |
| CASP3 | 0.1238153 |
| XPNPEP1 | 0.1237172 |
| SSR2 | 0.1235261 |
| LIMCH1 | 0.1235101 |
| SLC9A9 | 0.1234411 |
| MEX3D | 0.1234343 |
| SPSB4 | 0.1234106 |
| VRK1 | 0.1232617 |
| LYSMD4 | 0.1232564 |
| GPSM3 | 0.1232294 |
| POU2F2 | 0.1232054 |
| RASD2 | 0.1231741 |
| ETS1 | 0.1230748 |
| PGRMC1 | 0.1230607 |
| ERVV-1 | 0.1230402 |
| NDUFA9 | 0.1230372 |
| SSR1 | 0.1230316 |
| SLC39A1 | 0.1229748 |
| PDE9A | 0.1228799 |
| PHB | 0.1228615 |
| RCOR2 | 0.1228285 |
| ALDH1A3 | 0.1227989 |
| FOXQ1 | 0.1226769 |
| ADRB2 | 0.1226756 |
| MDFI | 0.1225871 |
| CD1A | 0.1225713 |
| PLA2G2A | 0.1223879 |
| LYSMD2 | 0.1223746 |
| ADSL | 0.1221617 |
| STAMBPL1 | 0.1221611 |
| FGB | 0.1221328 |
| ANXA8 | 0.1220619 |
| SPRR2E | 0.1219643 |
| DSCR8 | 0.1219211 |
| SMC4 | 0.1219080 |
| ACTR2 | 0.1219066 |
| SOX9 | 0.1218826 |
| SGOL1 | 0.1218106 |
| ASCC3 | 0.1216100 |
| UTP6 | 0.1214011 |
| TBPL1 | 0.1213685 |
| LAPTM4B | 0.1213197 |
| AP1B1 | 0.1213046 |
| FTHL17 | 0.1212659 |
| CECR5 | 0.1212649 |
| KLHL34 | 0.1211901 |
| OOEP | 0.1211583 |
| DNASE2 | 0.1211166 |
| CTSD | 0.1211151 |
| MAF | 0.1210319 |
| MICALL1 | 0.1210220 |
| EIF5A | 0.1208567 |
| APOBEC3H | 0.1208219 |
| BHLHE22 | 0.1207846 |
| PRAM1 | 0.1207526 |
| TMEM71 | 0.1207370 |
| HIST1H4C | 0.1206568 |
| CD40LG | 0.1206507 |
| CEBPG | 0.1206356 |
| TOMM5 | 0.1205227 |
| ACTL6A | 0.1204854 |
| REXO1 | 0.1204348 |
| MRPL47 | 0.1204262 |
| KCNE1L | 0.1203776 |
| ID4 | 0.1202994 |
| NANS | 0.1200694 |
| C3orf55 | 0.1199515 |
| PDCD10 | 0.1198120 |
| RASGEF1B | 0.1197644 |
| IL10RB | 0.1196047 |
| GIPR | 0.1195557 |
| CCDC167 | 0.1194598 |
| MAFB | 0.1194348 |
| MPST | 0.1193523 |
| ETV4 | 0.1192884 |
| ACSL4 | 0.1192656 |
| CRLF3 | 0.1192442 |
| A2M | 0.1192180 |
| TP53BP2 | 0.1191514 |
| RPL19 | 0.1190024 |
| GSTA4 | 0.1189620 |
| KIF23 | 0.1187891 |
| YBX3 | 0.1186895 |
| TMEM165 | 0.1185728 |
| STX17 | 0.1185230 |
| CHIC2 | 0.1184164 |
| C1orf158 | 0.1183981 |
| SP110 | 0.1183952 |
| PLTP | 0.1183807 |
| MFAP5 | 0.1182988 |
| FOLR2 | 0.1181768 |
| STAT2 | 0.1181529 |
| MSL3 | 0.1181278 |
| PSMA4 | 0.1179762 |
| PTK2B | 0.1179468 |
| PLXDC2 | 0.1179388 |
| C9orf40 | 0.1178980 |
| TAF11 | 0.1178665 |
| NAB1 | 0.1178174 |
| AGFG1 | 0.1177926 |
| OR1S2 | 0.1177392 |
| TRIM59 | 0.1176135 |
| OXGR1 | 0.1176064 |
| CLIC1 | 0.1175977 |
| GADD45A | 0.1175936 |
| CCNYL1 | 0.1175851 |
| ZNF438 | 0.1175829 |
| TBX19 | 0.1175279 |
| PARP2 | 0.1174788 |
| PLS3 | 0.1173552 |
| LINGO4 | 0.1172905 |
| EPYC | 0.1172141 |
| LRRC16B | 0.1170901 |
| SOSTDC1 | 0.1170482 |
| RNASE2 | 0.1170277 |
| BAZ1A | 0.1170227 |
| ASPHD2 | 0.1170048 |
| BEX5 | 0.1169438 |
| MAP2K3 | 0.1168761 |
| MOGS | 0.1168445 |
| BRIX1 | 0.1167340 |
| MICAL1 | 0.1165505 |
| ATP1A3 | 0.1165413 |
| BSPRY | 0.1164817 |
| GRHL1 | 0.1163803 |
| PRC1 | 0.1163387 |
| LSM6 | 0.1163297 |
| NT5C2 | 0.1161581 |
| DPAGT1 | 0.1161086 |
| IQGAP3 | 0.1159871 |
| VMA21 | 0.1159279 |
| SEC61A1 | 0.1158620 |
| GPX7 | 0.1158030 |
| TNIK | 0.1156946 |
| PCED1B | 0.1156938 |
| RASSF2 | 0.1155660 |
| TMEM170A | 0.1155451 |
| COLCA1 | 0.1155451 |
| RBM28 | 0.1155447 |
| HMCES | 0.1154452 |
| SLAIN1 | 0.1154325 |
| NKX1-2 | 0.1153832 |
| CDK2AP1 | 0.1153279 |
| MRPS17 | 0.1153249 |
| MAP3K8 | 0.1153236 |
| ZNF215 | 0.1153215 |
| CCL23 | 0.1152719 |
| PLCL2 | 0.1152411 |
| CAPN6 | 0.1150687 |
| GFPT2 | 0.1150047 |
| RPS7 | 0.1149394 |
| EPHB4 | 0.1149280 |
| WASF3 | 0.1148828 |
| HYOU1 | 0.1147514 |
| MRPL9 | 0.1146277 |
| PLOD1 | 0.1146225 |
| MID1 | 0.1145381 |
| LRP8 | 0.1144986 |
| ATAD2 | 0.1144662 |
| LRIG3 | 0.1144095 |
| POLR2D | 0.1144040 |
| ASF1A | 0.1143839 |
| NCS1 | 0.1143817 |
| UQCRH | 0.1143753 |
| CARD11 | 0.1143461 |
| EPB41L2 | 0.1142940 |
| STOML2 | 0.1142018 |
| KATNA1 | 0.1141944 |
| EN2 | 0.1140211 |
| RAP2A | 0.1139503 |
| LY86 | 0.1139459 |
| DNAJC5B | 0.1139371 |
| CLEC12A | 0.1139234 |
| MICAL3 | 0.1139074 |
| LCE1C | 0.1138478 |
| TUBA1A | 0.1138016 |
| DEF6 | 0.1137216 |
| PILRA | 0.1136822 |
| PARP14 | 0.1136398 |
| TCP11L1 | 0.1136225 |
| C8orf46 | 0.1135969 |
| C7orf13 | 0.1135231 |
| RNASEH2A | 0.1134813 |
| MMP17 | 0.1134608 |
| METTL8 | 0.1133864 |
| SLC22A23 | 0.1132875 |
| RBMS1 | 0.1132683 |
| TMCC2 | 0.1132415 |
| CARD16 | 0.1132171 |
| MPP6 | 0.1131011 |
| PLA2G4A | 0.1129806 |
| HEXA | 0.1129085 |
| NIPSNAP1 | 0.1129026 |
| NHP2L1 | 0.1126924 |
| RGS19 | 0.1126902 |
| MAGEA4 | 0.1126526 |
| CLDN1 | 0.1125589 |
| BUD13 | 0.1123471 |
| GTF3C5 | 0.1123391 |
| NUB1 | 0.1122617 |
| IFI27 | 0.1122526 |
| GFOD2 | 0.1122442 |
| STIP1 | 0.1122292 |
| TLR4 | 0.1121985 |
| CENPM | 0.1121144 |
| SNX20 | 0.1120734 |
| CD1B | 0.1120355 |
| COL4A2 | 0.1120238 |
| SRM | 0.1120229 |
| C1orf198 | 0.1120172 |
| HIST1H4B | 0.1119749 |
| RAD1 | 0.1119065 |
| UBE2E2 | 0.1118460 |
| CRHR2 | 0.1117160 |
| SLC37A1 | 0.1116628 |
| MMP19 | 0.1116532 |
| PITRM1 | 0.1116524 |
| ALPK2 | 0.1116487 |
| MAFF | 0.1116461 |
| DDX39A | 0.1116342 |
| U2AF1 | 0.1116318 |
| MPP1 | 0.1115138 |
| CCDC102A | 0.1114791 |
| GSTO1 | 0.1114558 |
| LSP1 | 0.1113228 |
| EEF1E1 | 0.1112961 |
| TDRD1 | 0.1112465 |
| PCNA | 0.1111937 |
| CD244 | 0.1111700 |
| STX7 | 0.1111233 |
| STAP1 | 0.1109743 |
| APOL4 | 0.1109586 |
| LBH | 0.1109218 |
| LHB | 0.1109066 |
| PBDC1 | 0.1109061 |
| MYBPC2 | 0.1108550 |
| MET | 0.1108203 |
| ECEL1 | 0.1108181 |
| LMNB2 | 0.1107798 |
| PCSK1N | 0.1107574 |
| OGFR | 0.1107555 |
| MT1HL1 | 0.1106294 |
| DOCK2 | 0.1106007 |
| NHSL1 | 0.1105835 |
| BUB1B | 0.1105329 |
| TMEM45B | 0.1104639 |
| DIAPH3 | 0.1103700 |
| DUS1L | 0.1103279 |
| LSM2 | 0.1103099 |
| SPRED1 | 0.1102514 |
| HIST1H2BG | 0.1101408 |
| VKORC1L1 | 0.1101109 |
| ATP5C1 | 0.1099734 |
| RFFL | 0.1099261 |
| IFFO1 | 0.1099095 |
| CEP76 | 0.1098959 |
| LMNA | 0.1097986 |
| THOC3 | 0.1097977 |
| MYOG | 0.1097781 |
| FAM83B | 0.1096053 |
| NPC1 | 0.1095226 |
| OBP2B | 0.1095050 |
| AGA | 0.1094410 |
| SMPDL3A | 0.1094400 |
| SLC8B1 | 0.1093254 |
| ARPC2 | 0.1093164 |
| STAC3 | 0.1092531 |
| RNF217 | 0.1092437 |
| SH2D1B | 0.1092431 |
| HEBP2 | 0.1091730 |
| MAP7D1 | 0.1090691 |
| DGCR14 | 0.1089891 |
| C19orf12 | 0.1089851 |
| TMEM14B | 0.1089392 |
| SOCS3 | 0.1089322 |
| CXCL2 | 0.1088840 |
| FAM122A | 0.1088441 |
| KLF11 | 0.1088431 |
| CHCHD10 | 0.1087840 |
| CTHRC1 | 0.1087616 |
| SMYD2 | 0.1087592 |
| FKBP15 | 0.1086498 |
| LDLR | 0.1084746 |
| KIAA0513 | 0.1084667 |
| SERPINB5 | 0.1084425 |
| HIST1H2BB | 0.1084243 |
| CCNJ | 0.1082883 |
| SBF1 | 0.1082851 |
| FAM20C | 0.1081807 |
| CNKSR3 | 0.1080414 |
| MRPL2 | 0.1079941 |
| NCAPG2 | 0.1079817 |
| MYCBP2 | 0.1079749 |
| MRPL39 | 0.1079679 |
| AKR1E2 | 0.1079449 |
| KIFC3 | 0.1079283 |
| DEDD | 0.1077622 |
| ZDHHC20 | 0.1077447 |
| SF3A2 | 0.1077283 |
| PRPF18 | 0.1076879 |
| ACTN1 | 0.1076828 |
| TBC1D2B | 0.1076350 |
| MUC4 | 0.1075985 |
| CD164 | 0.1075430 |
| MINA | 0.1075055 |
| JUNB | 0.1074204 |
| NRBP1 | 0.1073689 |
| RNF130 | 0.1073106 |
| TNRC6B | 0.1072114 |
| YWHAH | 0.1071510 |
| KIF2A | 0.1070218 |
| SRRD | 0.1069759 |
| HNRNPAB | 0.1068905 |
| NONO | 0.1067515 |
| SERBP1 | 0.1065854 |
| TUBD1 | 0.1065676 |
| SERPINA1 | 0.1065582 |
| MRPS6 | 0.1064228 |
| OSCAR | 0.1064158 |
| DENND4B | 0.1063423 |
| TRAF4 | 0.1063236 |
| C12orf49 | 0.1062262 |
| ZBTB24 | 0.1062023 |
| FCHO1 | 0.1061936 |
| TEX11 | 0.1061923 |
| SNX5 | 0.1061704 |
| OR10J5 | 0.1061642 |
| EXOSC8 | 0.1061491 |
| USP1 | 0.1061302 |
| CALR | 0.1061226 |
| METTL13 | 0.1060838 |
| NOTCH1 | 0.1060654 |
| ARG2 | 0.1059896 |
| CPSF3 | 0.1059374 |
| SMG5 | 0.1059345 |
| MRPL44 | 0.1058230 |
| LTV1 | 0.1058189 |
| MTHFD1 | 0.1058157 |
| SPSB1 | 0.1058140 |
| STK10 | 0.1057848 |
| WWTR1 | 0.1057828 |
| IKZF3 | 0.1057484 |
| TRIM43 | 0.1056628 |
| SIGLEC9 | 0.1056538 |
| DMRTA1 | 0.1056210 |
| PRR11 | 0.1055057 |
| GPBAR1 | 0.1054904 |
| CDCP1 | 0.1053088 |
| DEF8 | 0.1052518 |
| DNMT3A | 0.1052398 |
| CENPO | 0.1052123 |
| P2RX5 | 0.1051768 |
| FABP5 | 0.1051489 |
| RLBP1 | 0.1050670 |
| PPP1R10 | 0.1050521 |
| RAB32 | 0.1050410 |
| RPS12 | 0.1050131 |
| MTO1 | 0.1049987 |
| KIF21B | 0.1049848 |
| GEMIN4 | 0.1049125 |
| CD226 | 0.1048563 |
| F8A1 | 0.1048162 |
| CEP128 | 0.1047849 |
| CLIP4 | 0.1047295 |
| HINFP | 0.1047281 |
| NXT2 | 0.1046956 |
| SNRPD3 | 0.1046456 |
| TFF2 | 0.1046086 |
| FZD9 | 0.1045141 |
| LASP1 | 0.1044999 |
| ITGA4 | 0.1044776 |
| PSORS1C2 | 0.1044215 |
| RAP1A | 0.1043822 |
| NELFB | 0.1043136 |
| SSRP1 | 0.1042314 |
| ARPC5 | 0.1042265 |
| TBC1D4 | 0.1041953 |
| FRAT2 | 0.1041951 |
| LMAN2 | 0.1041789 |
| RNF145 | 0.1041762 |
| OGFOD1 | 0.1041639 |
| ACTN4 | 0.1041631 |
| DCUN1D5 | 0.1041118 |
| TAP2 | 0.1041038 |
| SQLE | 0.1040452 |
| PYGB | 0.1040201 |
| RDX | 0.1039514 |
| LAGE3 | 0.1039327 |
| IGSF23 | 0.1038481 |
| TSR1 | 0.1038380 |
| SNN | 0.1038094 |
| SATB1 | 0.1037947 |
| TRIM14 | 0.1037233 |
| FANCC | 0.1036932 |
| WDR34 | 0.1036912 |
| RPRML | 0.1036687 |
| PRIM2 | 0.1035937 |
| APP | 0.1034339 |
| KIAA0930 | 0.1034325 |
| GTPBP1 | 0.1033667 |
| SPRR3 | 0.1033646 |
| HIVEP1 | 0.1033621 |
| MYH9 | 0.1033418 |
| WDHD1 | 0.1032726 |
| MRPL15 | 0.1031057 |
| PI4K2B | 0.1030805 |
| CLCN4 | 0.1030628 |
| NECAP2 | 0.1030305 |
| GAB3 | 0.1029982 |
| ALDH1B1 | 0.1029978 |
| KCTD14 | 0.1029603 |
| SMO | 0.1029591 |
| TRIM26 | 0.1029536 |
| TACC3 | 0.1028893 |
| STT3A | 0.1027825 |
| PANX1 | 0.1027749 |
| HILPDA | 0.1027620 |
| ANKRD37 | 0.1027349 |
| ADPGK | 0.1027182 |
| COQ3 | 0.1027098 |
| LOXL4 | 0.1026199 |
| HAP1 | 0.1026089 |
| PTGIR | 0.1025962 |
| GRHL3 | 0.1025596 |
| MRPS18A | 0.1025545 |
| ZMIZ2 | 0.1025279 |
| SNX22 | 0.1025023 |
| ASCC2 | 0.1024819 |
| PSMC2 | 0.1024075 |
| CHD1L | 0.1024001 |
| FLVCR2 | 0.1023918 |
| SMARCB1 | 0.1023844 |
| RASGRP1 | 0.1023187 |
| PARL | 0.1022374 |
| FANCG | 0.1022107 |
| ACOT13 | 0.1022065 |
| POLA2 | 0.1022050 |
| SPHK1 | 0.1020570 |
| NDC1 | 0.1020390 |
| SPINT2 | 0.1020231 |
| CEP57L1 | 0.1020124 |
| DERL2 | 0.1020029 |
| NDUFAF7 | 0.1018776 |
| ATP6V1B2 | 0.1018130 |
| ZFAND5 | 0.1018055 |
| VRK2 | 0.1017913 |
| TPMT | 0.1017111 |
| TMEM74B | 0.1016840 |
| SPI1 | 0.1016325 |
| ANXA5 | 0.1016069 |
| PCTP | 0.1015917 |
| MRAP2 | 0.1011732 |
| PSMA3 | 0.1011349 |
| INPP4A | 0.1011010 |
| RSPO3 | 0.1010957 |
| LY9 | 0.1010805 |
| TBC1D22A | 0.1010477 |
| ASGR2 | 0.1010287 |
| SSX3 | 0.1009126 |
| RPS19BP1 | 0.1008876 |
| MAN1A1 | 0.1008464 |
| KCNB2 | 0.1007665 |
| RPS19 | 0.1007462 |
| HIST1H4E | 0.1007246 |
| TCF20 | 0.1007170 |
| SNRPA | 0.1006982 |
| HDGF | 0.1006754 |
| STRN4 | 0.1006661 |
| TRIM21 | 0.1006306 |
| TUBB4A | 0.1005761 |
| GALNT12 | 0.1005113 |
| PREB | 0.1004924 |
| PPARGC1B | 0.1004369 |
| C21orf58 | 0.1004245 |
| OPN3 | 0.1003729 |
| CAPZB | 0.1001664 |
| PSMC4 | 0.1001608 |
| ITGB4 | 0.1001314 |
| JAGN1 | 0.1001164 |
| UBE2L3 | 0.1000905 |
| SF3B5 | 0.1000804 |
| CLP1 | 0.0999465 |
| TM9SF2 | 0.0999407 |
| RNF149 | 0.0998750 |
| POLQ | 0.0998433 |
| KNTC1 | 0.0998297 |
| MKI67 | 0.0997652 |
| CSGALNACT1 | 0.0997507 |
| FBXO18 | 0.0997063 |
| CLDN10 | 0.0996781 |
| SPTBN2 | 0.0996101 |
| CCNB1 | 0.0995963 |
| CLTA | 0.0995393 |
| LAMC2 | 0.0994882 |
| MRPS5 | 0.0994859 |
| CBFB | 0.0994740 |
| DOCK11 | 0.0994459 |
| ERVV-2 | 0.0993986 |
| SF3A3 | 0.0993550 |
| EPRS | 0.0993518 |
| PSMB4 | 0.0993277 |
| DNM2 | 0.0992390 |
| BAX | 0.0991425 |
| CD200 | 0.0990904 |
| TROAP | 0.0990402 |
| PARVG | 0.0990140 |
| ITGA9 | 0.0989621 |
| GAN | 0.0989453 |
| REPS1 | 0.0988794 |
| CALU | 0.0988382 |
| ATP6V1C2 | 0.0988379 |
| GRN | 0.0988142 |
| TK1 | 0.0988097 |
| CDKAL1 | 0.0987390 |
| TBC1D1 | 0.0987331 |
| ZNF462 | 0.0987303 |
| C6orf106 | 0.0986863 |
| DEGS1 | 0.0985855 |
| AXL | 0.0985841 |
| CDC42BPG | 0.0985655 |
| DPH2 | 0.0984809 |
| MAGEA9 | 0.0984137 |
| PVRL1 | 0.0983858 |
| GAPDH | 0.0982298 |
| TSPAN32 | 0.0982125 |
| AHSA1 | 0.0981952 |
| CSTF2 | 0.0981755 |
| TRAM2 | 0.0981402 |
| RASGRP3 | 0.0981036 |
| RTKN2 | 0.0980775 |
| C15orf48 | 0.0980307 |
| ECHDC1 | 0.0980169 |
| IQCB1 | 0.0979919 |
| ARHGEF2 | 0.0979816 |
| CLDN14 | 0.0979504 |
| PUS3 | 0.0978833 |
| IFI35 | 0.0975995 |
| MPZL1 | 0.0975947 |
| TBC1D2 | 0.0975928 |
| TEAD3 | 0.0975021 |
| DNMT1 | 0.0974967 |
| STK17A | 0.0972297 |
| MPZL3 | 0.0972162 |
| GBA | 0.0971834 |
| EEF1G | 0.0971566 |
| TLE4 | 0.0971143 |
| SLC30A3 | 0.0970874 |
| GJD3 | 0.0970146 |
| TNFRSF10A | 0.0969807 |
| KCNJ10 | 0.0969595 |
| HSPA8 | 0.0968994 |
| PLD3 | 0.0967789 |
| STXBP6 | 0.0967058 |
| SLC34A2 | 0.0966830 |
| CALB2 | 0.0966374 |
| SSH2 | 0.0965254 |
| MEF2B | 0.0964636 |
| NDRG2 | 0.0964521 |
| ALG3 | 0.0964149 |
| CELF2 | 0.0963163 |
| FLAD1 | 0.0962929 |
| TXNDC12 | 0.0962815 |
| GPN1 | 0.0962525 |
| PAX1 | 0.0962092 |
| TATDN2 | 0.0961767 |
| AMPD3 | 0.0961555 |
| GJB3 | 0.0961517 |
| POC1A | 0.0961392 |
| TNFRSF12A | 0.0961095 |
| POP1 | 0.0960888 |
| NFKBIA | 0.0960807 |
| HMGB1 | 0.0960674 |
| SLC45A3 | 0.0959911 |
| ORC3 | 0.0959888 |
| ADRM1 | 0.0959310 |
| GTF2E2 | 0.0958189 |
| GRK5 | 0.0957460 |
| B3GNT7 | 0.0956713 |
| PABPC4L | 0.0956301 |
| GPR180 | 0.0956110 |
| PTMA | 0.0954938 |
| C11orf24 | 0.0954196 |
| MAP3K7 | 0.0954186 |
| C15orf52 | 0.0954115 |
| PSMA7 | 0.0953259 |
| MASTL | 0.0953175 |
| CHST12 | 0.0952512 |
| GSN | 0.0952070 |
| ZNF843 | 0.0951830 |
| STK24 | 0.0951774 |
| PIK3CD | 0.0951726 |
| RAB35 | 0.0951048 |
| TDRKH | 0.0951012 |
| ATP1A1 | 0.0949679 |
| ACTR3C | 0.0949430 |
| ASIC4 | 0.0949402 |
| NFASC | 0.0949089 |
| PSMD14 | 0.0948978 |
| EFHD2 | 0.0947775 |
| ADAM17 | 0.0946871 |
| YES1 | 0.0946040 |
| EMR1 | 0.0946003 |
| CWH43 | 0.0945467 |
| FBLIM1 | 0.0944550 |
| C16orf87 | 0.0943414 |
| RPA2 | 0.0943283 |
| PODXL2 | 0.0942442 |
| YARS | 0.0941831 |
| GPR150 | 0.0941616 |
| CCT6A | 0.0941406 |
| FUCA2 | 0.0941336 |
| SMOX | 0.0941169 |
| FAM118B | 0.0941089 |
| NUP88 | 0.0940985 |
| NFKB1 | 0.0940324 |
| RENBP | 0.0940309 |
| CSNK1D | 0.0940285 |
| OPTN | 0.0940187 |
| SEMA4A | 0.0939496 |
| CTRB2 | 0.0938395 |
| RHBDL2 | 0.0937932 |
| CCHCR1 | 0.0937611 |
| GCNT2 | 0.0937238 |
| FOXN2 | 0.0936739 |
| PSMB5 | 0.0936456 |
| DEPDC1 | 0.0936195 |
| SEH1L | 0.0935809 |
| MIS18A | 0.0935577 |
| GNG5 | 0.0935298 |
| SMTN | 0.0935085 |
| SYNGR1 | 0.0934935 |
| CDH1 | 0.0934399 |
| NLRC4 | 0.0934372 |
| SIGLEC1 | 0.0934100 |
| ZNF101 | 0.0933820 |
| PUS1 | 0.0933794 |
| CD80 | 0.0932888 |
| LIMD2 | 0.0932442 |
| TFIP11 | 0.0931949 |
| TECPR1 | 0.0931940 |
| CD33 | 0.0931353 |
| ACOT7 | 0.0930994 |
| PMF1 | 0.0930480 |
| CHD7 | 0.0929071 |
| AK4 | 0.0928746 |
| KLHL7 | 0.0928624 |
| LPAR2 | 0.0928512 |
| MED8 | 0.0928171 |
| C1orf54 | 0.0927349 |
| ELF4 | 0.0926726 |
| SH3KBP1 | 0.0926352 |
| PRSS27 | 0.0926065 |
| AVEN | 0.0925826 |
| ST3GAL6 | 0.0925813 |
| UXS1 | 0.0925209 |
| SEC61G | 0.0924339 |
| THUMPD3 | 0.0923003 |
| SIRPA | 0.0922071 |
| MACC1 | 0.0921682 |
| C19orf52 | 0.0921243 |
| TBXAS1 | 0.0921088 |
| NDEL1 | 0.0920941 |
| ATL2 | 0.0920666 |
| FAM207A | 0.0920219 |
| RHOH | 0.0919944 |
| NDUFA6 | 0.0919555 |
| S100A1 | 0.0918668 |
| IL12RB1 | 0.0918628 |
| WDFY4 | 0.0918615 |
| DPYSL5 | 0.0917704 |
| GPI | 0.0917543 |
| DPEP2 | 0.0917140 |
| CLPS | 0.0916508 |
| UNC93B1 | 0.0916144 |
| FLT3LG | 0.0915731 |
| MTPAP | 0.0915467 |
| DECR1 | 0.0915320 |
| HPSE | 0.0915091 |
| ELF3 | 0.0914741 |
| PPP1CA | 0.0914282 |
| TCF19 | 0.0914177 |
| CKLF | 0.0914158 |
| PKM | 0.0913863 |
| CAMK2D | 0.0913609 |
| FAM21C | 0.0913452 |
| GRIN2D | 0.0913104 |
| AGMAT | 0.0912905 |
| MAPK13 | 0.0912820 |
| PSMD7 | 0.0912683 |
| NUP210 | 0.0912610 |
| SNRPG | 0.0912455 |
| LRP3 | 0.0912013 |
| DSE | 0.0911593 |
| SIPA1 | 0.0911353 |
| CPNE7 | 0.0910628 |
| FAM89A | 0.0910552 |
| PDCD2L | 0.0910191 |
| POU3F1 | 0.0908599 |
| LGR6 | 0.0908135 |
| RCC2 | 0.0907436 |
| SIGMAR1 | 0.0906808 |
| MARCKSL1 | 0.0906358 |
| UBE2A | 0.0905762 |
| EED | 0.0904631 |
| MANF | 0.0904614 |
| SAMM50 | 0.0904505 |
| SLC35B3 | 0.0904188 |
| TLR9 | 0.0901970 |
| PNLDC1 | 0.0901552 |
| TOMM40 | 0.0901149 |
| HMX1 | 0.0900721 |
| OR7C2 | 0.0899812 |
| WSB2 | 0.0899481 |
| FNDC9 | 0.0899347 |
| FBXO27 | 0.0898891 |
| MOB3A | 0.0898105 |
| AUNIP | 0.0897367 |
| PGAM1 | 0.0896111 |
| MRPS15 | 0.0896093 |
| NCAPH | 0.0895166 |
| WDR46 | 0.0894948 |
| NOP2 | 0.0894422 |
| S100A3 | 0.0894296 |
| C1GALT1 | 0.0894079 |
| AATF | 0.0893699 |
| SGSM3 | 0.0893027 |
| GP1BA | 0.0892813 |
| GMPPB | 0.0892764 |
| ACAA2 | 0.0891899 |
| KLF7 | 0.0891401 |
| ARID3B | 0.0891165 |
| HIST1H3E | 0.0890679 |
| ELOVL1 | 0.0890491 |
| MARS | 0.0890440 |
| ALDH18A1 | 0.0890363 |
| RAN | 0.0890195 |
| CD1E | 0.0890035 |
| FAM127A | 0.0889962 |
| WISP3 | 0.0889916 |
| WFDC10B | 0.0889418 |
| FAM98A | 0.0888995 |
| PRKAA1 | 0.0888922 |
| TNFRSF14 | 0.0888827 |
| RHOV | 0.0888289 |
| HSPA6 | 0.0888254 |
| PPAP2C | 0.0887891 |
| HOXB4 | 0.0886894 |
| GUCY1A3 | 0.0886776 |
| ME2 | 0.0886185 |
| ELAC1 | 0.0886147 |
| MGAT3 | 0.0885852 |
| PRDX1 | 0.0885306 |
| MRPL37 | 0.0885174 |
| ARHGAP10 | 0.0885086 |
| FRMPD3 | 0.0884027 |
| AAED1 | 0.0883775 |
| ATG5 | 0.0883460 |
| HAMP | 0.0883028 |
| TKT | 0.0882865 |
| GORASP2 | 0.0882747 |
| RRP1 | 0.0882642 |
| IRF7 | 0.0882386 |
| DAB1 | 0.0882173 |
| P4HB | 0.0881873 |
| WDTC1 | 0.0881338 |
| COPB2 | 0.0881024 |
| TMEM206 | 0.0880434 |
| CCM2 | 0.0879873 |
| ATP2C1 | 0.0878494 |
| CDK6 | 0.0878068 |
| TAX1BP3 | 0.0877077 |
| DESI2 | 0.0876863 |
| SLC33A1 | 0.0876766 |
| CDC34 | 0.0876573 |
| GALK2 | 0.0876230 |
| SH3BP1 | 0.0875723 |
| TLDC1 | 0.0875476 |
| SIX2 | 0.0874627 |
| FAM60A | 0.0874499 |
| CADPS2 | 0.0873661 |
| DUSP26 | 0.0872900 |
| NCK2 | 0.0872252 |
| NLRP3 | 0.0872144 |
| MORC2 | 0.0872084 |
| LIPG | 0.0871853 |
| HMHB1 | 0.0871643 |
| NEUROG3 | 0.0870801 |
| STAP2 | 0.0870470 |
| CCDC88B | 0.0870451 |
| EZR | 0.0869930 |
| SND1 | 0.0869711 |
| FBXO45 | 0.0869224 |
| DDX28 | 0.0869117 |
| RPP38 | 0.0869087 |
| DTNBP1 | 0.0868582 |
| PAK4 | 0.0868041 |
| ATAD3A | 0.0867812 |
| ASB9 | 0.0867513 |
| DMWD | 0.0867065 |
| PTGDR | 0.0866743 |
| ZNF280C | 0.0865615 |
| PPAN | 0.0865468 |
| UCHL1 | 0.0864869 |
| FAM96B | 0.0864811 |
| TMEM109 | 0.0864697 |
| NRAS | 0.0863233 |
| CAPN2 | 0.0863117 |
| LPCAT1 | 0.0862943 |
| LYNX1 | 0.0862294 |
| LTB4R2 | 0.0861790 |
| GFOD1 | 0.0860839 |
| FH | 0.0860381 |
| HIST1H2BM | 0.0860288 |
| SMC1B | 0.0859471 |
| HIST1H3B | 0.0859183 |
| CEACAM3 | 0.0858950 |
| TAPBP | 0.0858793 |
| SDHD | 0.0858670 |
| TBCC | 0.0858560 |
| SLC25A28 | 0.0858087 |
| ATF3 | 0.0857758 |
| ZNF503 | 0.0857746 |
| GOT1 | 0.0856604 |
| KPNA3 | 0.0855957 |
| WNT11 | 0.0855725 |
| SCYL1 | 0.0855686 |
| MC5R | 0.0855433 |
| UGT2B10 | 0.0855345 |
| UCHL5 | 0.0855066 |
| ZNF71 | 0.0853421 |
| FAM129B | 0.0853276 |
| FPR2 | 0.0853143 |
| NTNG2 | 0.0852236 |
| ZNF232 | 0.0851814 |
| VSNL1 | 0.0851643 |
| CCDC137 | 0.0851032 |
| SYCE1L | 0.0850934 |
| METRNL | 0.0850188 |
| STK40 | 0.0849760 |
| SNAI1 | 0.0849680 |
| S100A14 | 0.0849593 |
| TXN | 0.0849577 |
| PRKD2 | 0.0848399 |
| FKBP2 | 0.0848360 |
| UPK3B | 0.0847882 |
| NOD1 | 0.0847570 |
| MYO9B | 0.0846957 |
| FAM58A | 0.0846934 |
| PHF23 | 0.0846838 |
| PARP9 | 0.0846828 |
| GLB1 | 0.0845809 |
| PCDHB2 | 0.0844033 |
| EDEM2 | 0.0841208 |
| HS3ST1 | 0.0841037 |
| LGALS8 | 0.0840963 |
| FBXL19 | 0.0840446 |
| TC2N | 0.0839868 |
| NT5C3A | 0.0838945 |
| PITX3 | 0.0838859 |
| PSMB6 | 0.0838837 |
| POLR3D | 0.0838065 |
| FAM222B | 0.0837743 |
| GLO1 | 0.0837504 |
| PAGE5 | 0.0837192 |
| CEACAM7 | 0.0836916 |
| STARD7 | 0.0836719 |
| TIAM1 | 0.0836623 |
| KCNE3 | 0.0836349 |
| SNRNP70 | 0.0836311 |
| KIF18A | 0.0835329 |
| ARPC4 | 0.0835300 |
| SURF4 | 0.0834704 |
| CLEC2B | 0.0834701 |
| TYMP | 0.0834619 |
| CYP1B1 | 0.0834457 |
| IVL | 0.0834344 |
| KIF18B | 0.0834341 |
| SLC35B2 | 0.0833706 |
| OAT | 0.0833575 |
| KDELR2 | 0.0833453 |
| TRAPPC3 | 0.0833002 |
| CCT4 | 0.0832324 |
| COPS3 | 0.0831937 |
| ASIP | 0.0831699 |
| FGFR4 | 0.0831696 |
| EPHB2 | 0.0830936 |
| ARSA | 0.0830716 |
| DIO2 | 0.0830490 |
| CD3E | 0.0830229 |
| ACTG1 | 0.0829055 |
| BAIAP2L2 | 0.0828766 |
| SPACA3 | 0.0828744 |
| PPP2R5D | 0.0827920 |
| DPH3 | 0.0827618 |
| CLEC4G | 0.0825939 |
| VIMP | 0.0825886 |
| NPM3 | 0.0825231 |
| CORT | 0.0825228 |
| OAZ3 | 0.0825157 |
| NAE1 | 0.0824957 |
| INTS8 | 0.0824836 |
| ERAL1 | 0.0823626 |
| EIF4E2 | 0.0823479 |
| CCL24 | 0.0823178 |
| RANBP9 | 0.0822539 |
| ZDHHC5 | 0.0822478 |
| KLHDC3 | 0.0821836 |
| TRIP10 | 0.0821681 |
| SGOL2 | 0.0821671 |
| TRRAP | 0.0821361 |
| RAB8B | 0.0821283 |
| DERL1 | 0.0821138 |
| DMBT1 | 0.0821045 |
| P2RX7 | 0.0820996 |
| RIBC2 | 0.0820587 |
| PLEKHS1 | 0.0820569 |
| UBAP2 | 0.0820113 |
| MATK | 0.0819917 |
| IL20RB | 0.0818724 |
| JRKL | 0.0818299 |
| KLF8 | 0.0817833 |
| CD180 | 0.0817758 |
| KIAA1432 | 0.0817521 |
| FAM214B | 0.0817372 |
| CWC15 | 0.0816929 |
| CAD | 0.0816853 |
| PDE6G | 0.0816759 |
| CAPS | 0.0816404 |
| RALY | 0.0816352 |
| CPNE8 | 0.0813633 |
| PTRH2 | 0.0813200 |
| POLE3 | 0.0812609 |
| SLC25A13 | 0.0812589 |
| ALDH1L2 | 0.0812424 |
| CCR6 | 0.0812009 |
| NXN | 0.0811905 |
| RAD18 | 0.0811882 |
| SAAL1 | 0.0811761 |
| SDHC | 0.0811629 |
| COG5 | 0.0811163 |
| SP140L | 0.0811158 |
| SCO1 | 0.0811115 |
| MAPRE2 | 0.0811109 |
| CUTC | 0.0810906 |
| IRAK1 | 0.0810669 |
| SFN | 0.0809616 |
| TACO1 | 0.0809486 |
| FOXB1 | 0.0809439 |
| ERP29 | 0.0808965 |
| DUX4 | 0.0808907 |
| SLC17A7 | 0.0807744 |
| CLDND1 | 0.0807619 |
| SAMHD1 | 0.0807483 |
| LHX1 | 0.0807149 |
| KIRREL3 | 0.0806728 |
| SF3B3 | 0.0806722 |
| CCND3 | 0.0806102 |
| PYHIN1 | 0.0805843 |
| PTX3 | 0.0805067 |
| CCNB1IP1 | 0.0804807 |
| STK4 | 0.0803412 |
| SFMBT2 | 0.0803097 |
| LYAR | 0.0802996 |
| DAPK2 | 0.0802593 |
| RABGAP1L | 0.0802311 |
| SLC37A4 | 0.0802150 |
| SVOPL | 0.0802021 |
| PDGFRA | 0.0801998 |
| CALM3 | 0.0801212 |
| SRPRB | 0.0801209 |
| DUS2 | 0.0801023 |
| HELLS | 0.0800973 |
| CD209 | 0.0800843 |
| PAPSS1 | 0.0800743 |
| ZNF695 | 0.0800742 |
| OR4X2 | 0.0800597 |
| UBAP1 | 0.0800305 |
| SDCCAG3 | 0.0800297 |
| DDT | 0.0800073 |
| KCNH3 | 0.0799823 |
| MMGT1 | 0.0799511 |
| STAT3 | 0.0799492 |
| DCAF7 | 0.0799445 |
| COCH | 0.0798982 |
| EPHA1 | 0.0798849 |
| PPP2R5C | 0.0797758 |
| DHRS13 | 0.0796840 |
| CDCA7L | 0.0796829 |
| SELE | 0.0796631 |
| AFG3L2 | 0.0796609 |
| IGF2BP2 | 0.0796338 |
| EPHX3 | 0.0796166 |
| TMEM167A | 0.0795479 |
| EMC8 | 0.0794935 |
| RPP25 | 0.0794549 |
| SHC4 | 0.0794328 |
| NXT1 | 0.0793236 |
| PPP1R14A | 0.0792789 |
| DDX58 | 0.0792281 |
| COX5A | 0.0791862 |
| HCCS | 0.0791284 |
| PFN2 | 0.0790860 |
| PMPCA | 0.0790810 |
| CCNY | 0.0790783 |
| CTDNEP1 | 0.0790782 |
| KIAA1199 | 0.0789827 |
| INTS7 | 0.0789212 |
| NDUFAF4 | 0.0788729 |
| CPA4 | 0.0788133 |
| NT5E | 0.0787410 |
| KIN | 0.0787248 |
| PTDSS1 | 0.0787177 |
| PPIF | 0.0786883 |
| PIWIL4 | 0.0786171 |
| ARSB | 0.0786139 |
| DNLZ | 0.0786002 |
| TPI1 | 0.0785915 |
| CIAPIN1 | 0.0785632 |
| SLC9A6 | 0.0785402 |
| ITGB8 | 0.0785384 |
| DARS | 0.0784753 |
| EBP | 0.0784655 |
| MPC1 | 0.0784383 |
| HIRA | 0.0784344 |
| MED15 | 0.0784274 |
| HCRTR1 | 0.0783740 |
| OLR1 | 0.0783508 |
| UTS2 | 0.0783135 |
| PTTG1IP | 0.0782105 |
| TRAF2 | 0.0782077 |
| ANXA4 | 0.0781922 |
| CABP5 | 0.0781685 |
| WDR53 | 0.0780979 |
| BCAT1 | 0.0780937 |
| ARID5A | 0.0780474 |
| NCAPD3 | 0.0780381 |
| LYL1 | 0.0780092 |
| SNX8 | 0.0779772 |
| CLSPN | 0.0779755 |
| CENPBD1 | 0.0779565 |
| LXN | 0.0779492 |
| C12orf4 | 0.0779374 |
| SMAGP | 0.0778909 |
| ZCCHC11 | 0.0778805 |
| LTA | 0.0778152 |
| C1orf116 | 0.0777982 |
| TPSG1 | 0.0777076 |
| TMEM11 | 0.0776617 |
| AGPAT3 | 0.0776264 |
| RSRC1 | 0.0775388 |
| DUS3L | 0.0775152 |
| VPS9D1 | 0.0774452 |
| MFSD12 | 0.0774346 |
| C5orf46 | 0.0774265 |
| ADK | 0.0773649 |
| KLHL36 | 0.0773250 |
| HMGB2 | 0.0773213 |
| PRPS1L1 | 0.0773018 |
| MON1B | 0.0772876 |
| DHX38 | 0.0772772 |
| TMEM61 | 0.0771915 |
| SCNM1 | 0.0771517 |
| DNA2 | 0.0770976 |
| KALRN | 0.0770542 |
| PSMG2 | 0.0770283 |
| SLC13A3 | 0.0770166 |
| URB2 | 0.0769929 |
| SUSD1 | 0.0769927 |
| PRB3 | 0.0769661 |
| PPARD | 0.0768977 |
| WDR91 | 0.0768845 |
| RNASEH2B | 0.0768461 |
| ZNF711 | 0.0768162 |
| ARMC6 | 0.0767556 |
| SLC39A12 | 0.0767021 |
| PRPF3 | 0.0766045 |
| CNTNAP3B | 0.0765368 |
| AP1M1 | 0.0765121 |
| SHD | 0.0764339 |
| DHX36 | 0.0764146 |
| LACTB | 0.0763036 |
| GATA6 | 0.0761890 |
| FZD7 | 0.0761410 |
| CCDC77 | 0.0761292 |
| PLIN3 | 0.0760794 |
| FBXW7 | 0.0760748 |
| RHPN2 | 0.0760523 |
| AIM1L | 0.0760459 |
| KIAA0100 | 0.0760244 |
| PEPD | 0.0760024 |
| DRAM2 | 0.0759881 |
| RCL1 | 0.0759415 |
| PDSS2 | 0.0758995 |
| FLII | 0.0758587 |
| PSMA5 | 0.0758255 |
| RARRES3 | 0.0758191 |
| AMN | 0.0757875 |
| CNDP2 | 0.0757556 |
| TMEM105 | 0.0757397 |
| ANXA2 | 0.0757276 |
| RAI14 | 0.0756965 |
| IKBKG | 0.0756898 |
| C1GALT1C1 | 0.0756801 |
| ITLN1 | 0.0756732 |
| GSTA3 | 0.0756632 |
| RPS10 | 0.0756520 |
| ECH1 | 0.0756328 |
| C1orf85 | 0.0756030 |
| RPL7L1 | 0.0755890 |
| CNDP1 | 0.0755336 |
| LRRC61 | 0.0755199 |
| CDK3 | 0.0754558 |
| POU2F3 | 0.0754489 |
| DLGAP3 | 0.0753701 |
| ACY3 | 0.0753292 |
| PIR | 0.0753109 |
| NAA50 | 0.0753093 |
| CCDC9 | 0.0752447 |
| PIEZO1 | 0.0752088 |
| NUP85 | 0.0751440 |
| TKTL1 | 0.0751409 |
| TESPA1 | 0.0751146 |
| SLFN5 | 0.0750668 |
| GINS1 | 0.0750667 |
| COL23A1 | 0.0749879 |
| RHOU | 0.0749248 |
| POP4 | 0.0748816 |
| DNPH1 | 0.0747948 |
| SKA2 | 0.0747158 |
| MRPL36 | 0.0747142 |
| ARRDC1 | 0.0746893 |
| ADAM28 | 0.0746890 |
| MRPS22 | 0.0746629 |
| TIMM23 | 0.0746313 |
| HSH2D | 0.0746279 |
| DR1 | 0.0746132 |
| ZDHHC9 | 0.0746006 |
| SIGLEC7 | 0.0745786 |
| PRPF8 | 0.0745470 |
| ENDOD1 | 0.0745357 |
| SPRR1A | 0.0745328 |
| ALG6 | 0.0745327 |
| PYCARD | 0.0744654 |
| FBXO17 | 0.0744449 |
| FOXK2 | 0.0744049 |
| PLK3 | 0.0743979 |
| PDCL3 | 0.0743178 |
| TMEM55B | 0.0742694 |
| DOK5 | 0.0742654 |
| MFAP2 | 0.0742564 |
| SLC15A4 | 0.0742477 |
| MIEF1 | 0.0742461 |
| LIN9 | 0.0742177 |
| PTGS2 | 0.0742098 |
| MIS18BP1 | 0.0741541 |
| NCALD | 0.0741017 |
| PKMYT1 | 0.0740977 |
| TTC13 | 0.0740971 |
| NOL11 | 0.0740923 |
| GPRIN1 | 0.0740884 |
| UBAC1 | 0.0739723 |
| SENP3 | 0.0739695 |
| GRB10 | 0.0739655 |
| FNDC1 | 0.0739093 |
| KIF19 | 0.0738220 |
| ELMO1 | 0.0738190 |
| CHTF8 | 0.0737782 |
| SULF1 | 0.0737396 |
| CEACAM4 | 0.0737349 |
| PROSER1 | 0.0736572 |
| BTN3A1 | 0.0736357 |
| TRA2B | 0.0736077 |
| SOST | 0.0736036 |
| PSTPIP2 | 0.0735735 |
| PGAM5 | 0.0735431 |
| GML | 0.0735158 |
| MAGOH | 0.0734908 |
| GGT5 | 0.0734726 |
| PLEKHA2 | 0.0734668 |
| NFKB2 | 0.0734310 |
| PYDC1 | 0.0733498 |
| ARID5B | 0.0732574 |
| PLP2 | 0.0732481 |
| ALPPL2 | 0.0732401 |
| WDR5 | 0.0732060 |
| MEF2C | 0.0731664 |
| UBQLN4 | 0.0731485 |
| ADPRHL2 | 0.0730963 |
| TMEM177 | 0.0730718 |
| ALPP | 0.0729977 |
| PLEKHA8 | 0.0729589 |
| MFSD1 | 0.0729482 |
| NOL7 | 0.0729468 |
| GYG1 | 0.0728720 |
| PPIL1 | 0.0728498 |
| UHRF2 | 0.0728489 |
| CDSN | 0.0728162 |
| PAPD7 | 0.0727732 |
| BANF1 | 0.0727411 |
| HIST1H2BJ | 0.0727052 |
| ZDHHC18 | 0.0726573 |
| TMEM100 | 0.0726337 |
| CREG1 | 0.0724841 |
| LRRC8B | 0.0723911 |
| SSSCA1 | 0.0723813 |
| SLC11A1 | 0.0723109 |
| EIF3L | 0.0722896 |
| NKX2-5 | 0.0722792 |
| LACC1 | 0.0722604 |
| SHB | 0.0722445 |
| SKAP2 | 0.0722294 |
| TBC1D22B | 0.0721771 |
| GART | 0.0721748 |
| FBXO7 | 0.0721281 |
| PRKAG2 | 0.0721160 |
| CCDC6 | 0.0721134 |
| RAF1 | 0.0721082 |
| TAGLN | 0.0720394 |
| ESRRA | 0.0720247 |
| JMJD6 | 0.0720209 |
| KIAA0247 | 0.0719710 |
| ADAMTS7 | 0.0719313 |
| MRPL4 | 0.0719101 |
| TMEM214 | 0.0718554 |
| KRT13 | 0.0717210 |
| AICDA | 0.0717011 |
| SIK1 | 0.0716814 |
| YBX2 | 0.0716762 |
| SLA2 | 0.0716461 |
| FAM136A | 0.0715789 |
| DZIP1 | 0.0715515 |
| TSSC1 | 0.0715302 |
| GTPBP2 | 0.0714116 |
| SH3GL3 | 0.0714092 |
| HIATL1 | 0.0714078 |
| B4GALT4 | 0.0713534 |
| NDUFS2 | 0.0713343 |
| SH3BGRL3 | 0.0713284 |
| PITPNM1 | 0.0712481 |
| LHPP | 0.0712471 |
| CLIC5 | 0.0712177 |
| POLDIP2 | 0.0711998 |
| ASF1B | 0.0711961 |
| SYVN1 | 0.0711807 |
| CA8 | 0.0711247 |
| BRI3 | 0.0711127 |
| ANKRD33 | 0.0710759 |
| TAAR5 | 0.0710674 |
| IER2 | 0.0710434 |
| LDHA | 0.0709499 |
| TOX | 0.0709146 |
| SDF2 | 0.0709126 |
| ZMYND19 | 0.0708825 |
| KREMEN1 | 0.0708689 |
| LILRA2 | 0.0707630 |
| ESRP2 | 0.0707276 |
| IRX4 | 0.0706753 |
| NFATC3 | 0.0706714 |
| YEATS2 | 0.0706643 |
| PLA2G15 | 0.0706339 |
| ORC1 | 0.0705692 |
| ANXA8L1 | 0.0705688 |
| HIST1H1B | 0.0705285 |
| PGK1 | 0.0705196 |
| DCN | 0.0704654 |
| ATF5 | 0.0704621 |
| VIM | 0.0704297 |
| METTL7A | 0.0704250 |
| PSMD12 | 0.0704177 |
| MTA2 | 0.0704038 |
| CHCHD3 | 0.0703944 |
| IRAK2 | 0.0703932 |
| PPRC1 | 0.0703568 |
| NOB1 | 0.0703335 |
| LACE1 | 0.0703301 |
| RRP7A | 0.0702991 |
| ARHGAP23 | 0.0702800 |
| TPM1 | 0.0702621 |
| GPR161 | 0.0701616 |
| OSTC | 0.0701301 |
| CKMT1A | 0.0700623 |
| SEC24A | 0.0700588 |
| TREML2 | 0.0700030 |
| SMU1 | 0.0699956 |
| CDC42EP5 | 0.0699733 |
| EPCAM | 0.0698906 |
| SMAP2 | 0.0698814 |
| KANK1 | 0.0698545 |
| ALOXE3 | 0.0698253 |
| MOSPD1 | 0.0697753 |
| MRS2 | 0.0697600 |
| GAR1 | 0.0697545 |
| PCMT1 | 0.0697360 |
| SRSF2 | 0.0697331 |
| PES1 | 0.0697324 |
| PLAG1 | 0.0697169 |
| PRRC2C | 0.0697083 |
| SNX6 | 0.0696978 |
| SLC44A3 | 0.0696925 |
| GABARAP | 0.0696814 |
| SPPL2A | 0.0696563 |
| RNF219 | 0.0696495 |
| P2RX3 | 0.0696270 |
| RPE | 0.0696221 |
| ABI1 | 0.0696204 |
| CMTM3 | 0.0696031 |
| PARM1 | 0.0695856 |
| TMEM147 | 0.0695744 |
| ZDHHC6 | 0.0695195 |
| CBL | 0.0695144 |
| ANKS1A | 0.0694627 |
| HIST1H3I | 0.0693904 |
| ITPRIPL1 | 0.0692640 |
| SLC26A9 | 0.0692074 |
| AMPD1 | 0.0691992 |
| CCT7 | 0.0691763 |
| FRMD1 | 0.0691375 |
| NR2C2 | 0.0691362 |
| UPF3B | 0.0690625 |
| ABCC10 | 0.0690471 |
| THEM5 | 0.0689252 |
| NCSTN | 0.0688290 |
| FOXO3 | 0.0688028 |
| LRRC34 | 0.0687664 |
| IL1RN | 0.0686629 |
| CLDN7 | 0.0686529 |
| POLR2F | 0.0686169 |
| FHOD1 | 0.0685154 |
| CCDC107 | 0.0684884 |
| MYH3 | 0.0684812 |
| OXA1L | 0.0684345 |
| GLG1 | 0.0684147 |
| CAB39 | 0.0683805 |
| PITPNA | 0.0683408 |
| PSMD8 | 0.0683295 |
| FGD2 | 0.0682925 |
| PTPRO | 0.0682754 |
| ERLIN1 | 0.0682552 |
| B3GALNT2 | 0.0682266 |
| YKT6 | 0.0681917 |
| PMFBP1 | 0.0681672 |
| C19orf47 | 0.0681501 |
| MRPS9 | 0.0681125 |
| ACTR1A | 0.0681067 |
| MSH2 | 0.0680969 |
| RASGRF1 | 0.0680623 |
| TFAP2C | 0.0680135 |
| ENOX2 | 0.0680062 |
| VCL | 0.0679214 |
| NKX2-3 | 0.0678894 |
| TOMM6 | 0.0678771 |
| YWHAZ | 0.0678287 |
| HPS5 | 0.0678254 |
| INSIG2 | 0.0678076 |
| HS3ST3B1 | 0.0677899 |
| FAM101B | 0.0677774 |
| KIF14 | 0.0677452 |
| CALML3 | 0.0676952 |
| KLHL24 | 0.0676871 |
| SLC38A10 | 0.0676781 |
| SERPINE2 | 0.0676240 |
| FAR2 | 0.0675891 |
| RBM7 | 0.0675214 |
| PPP2R3C | 0.0674576 |
| BMP2K | 0.0674363 |
| PCYT2 | 0.0674020 |
| FXYD6 | 0.0673971 |
| RNF26 | 0.0673397 |
| MYO7A | 0.0672264 |
| FXYD2 | 0.0672238 |
| UGT2B28 | 0.0672176 |
| ABCA12 | 0.0672070 |
| FBXO46 | 0.0671893 |
| ORAI1 | 0.0671599 |
| C20orf24 | 0.0671512 |
| DAP | 0.0671422 |
| MYBPC3 | 0.0671129 |
| POLR1C | 0.0670974 |
| KPNA4 | 0.0670905 |
| DYNLL2 | 0.0670534 |
| KCTD12 | 0.0670449 |
| RNF168 | 0.0670059 |
| MIIP | 0.0669739 |
| ADAR | 0.0669735 |
| C15orf27 | 0.0669630 |
| HRH1 | 0.0669566 |
| THAP11 | 0.0669497 |
| ABHD5 | 0.0669476 |
| WISP2 | 0.0669377 |
| NMB | 0.0668969 |
| ARF5 | 0.0668405 |
| PWP2 | 0.0667865 |
| ABCE1 | 0.0667665 |
| CCT3 | 0.0667622 |
| KRTAP4-11 | 0.0667519 |
| MIER2 | 0.0667501 |
| NSDHL | 0.0667414 |
| FANCD2 | 0.0667318 |
| KLF13 | 0.0667191 |
| CACNA1E | 0.0667188 |
| ARHGEF5 | 0.0667026 |
| HSPA14 | 0.0666692 |
| IL1R1 | 0.0666402 |
| FOXO1 | 0.0666153 |
| COPG1 | 0.0665983 |
| MYOZ1 | 0.0665781 |
| LIN28B | 0.0665530 |
| UFC1 | 0.0665491 |
| MYRF | 0.0664562 |
| FTSJ1 | 0.0664438 |
| SF3B2 | 0.0663297 |
| GANAB | 0.0663225 |
| SLC16A10 | 0.0662870 |
| MSMO1 | 0.0662582 |
| ANGPT1 | 0.0662540 |
| ETV6 | 0.0662064 |
| APCDD1 | 0.0661792 |
| PQLC1 | 0.0661784 |
| DENND3 | 0.0661458 |
| LYRM4 | 0.0661201 |
| ZNF22 | 0.0661087 |
| SET | 0.0660057 |
| RPS16 | 0.0659783 |
| PHF11 | 0.0659290 |
| DDX21 | 0.0659161 |
| FAM32A | 0.0659114 |
| HIST1H2BE | 0.0659061 |
| RIF1 | 0.0659006 |
| GPR110 | 0.0658469 |
| DGKZ | 0.0658409 |
| RPL18A | 0.0657827 |
| LIPA | 0.0657179 |
| KCNQ3 | 0.0656964 |
| SERTAD2 | 0.0656480 |
| PABPN1 | 0.0656113 |
| DYNC1H1 | 0.0655949 |
| ZUFSP | 0.0655774 |
| TPRXL | 0.0655533 |
| HIST1H4L | 0.0655111 |
| RCC1 | 0.0654885 |
| PBK | 0.0654885 |
| TUBA1B | 0.0654778 |
| MLLT6 | 0.0654590 |
| CHAF1A | 0.0654586 |
| DPYSL2 | 0.0654405 |
| YME1L1 | 0.0654361 |
| RBM42 | 0.0654161 |
| LRRC42 | 0.0653777 |
| DEPDC7 | 0.0653643 |
| NPPC | 0.0653486 |
| PAK1 | 0.0652914 |
| PRAP1 | 0.0652801 |
| NPTX2 | 0.0652653 |
| NUDT19 | 0.0652627 |
| GNB1L | 0.0652165 |
| POLR2H | 0.0652146 |
| CXorf38 | 0.0651495 |
| C8orf76 | 0.0651364 |
| C5orf56 | 0.0651295 |
| ACTL7A | 0.0650568 |
| DSCR3 | 0.0649059 |
| CDH22 | 0.0648849 |
| UTF1 | 0.0648570 |
| UBXN2A | 0.0648533 |
| ADAMTS3 | 0.0648505 |
| FES | 0.0647813 |
| OR5V1 | 0.0647775 |
| KRBA1 | 0.0647575 |
| CLPB | 0.0647574 |
| NCAPH2 | 0.0647464 |
| ARF1 | 0.0647303 |
| NAAA | 0.0647301 |
| PKP1 | 0.0647252 |
| SP100 | 0.0647230 |
| FTH1 | 0.0646869 |
| BRK1 | 0.0646630 |
| HSD17B11 | 0.0646288 |
| TTC9C | 0.0645922 |
| TAF5 | 0.0645767 |
| G0S2 | 0.0645731 |
| CDC6 | 0.0645599 |
| UBE2G1 | 0.0645314 |
| OR1D2 | 0.0645103 |
| POLE2 | 0.0644701 |
| WNT5B | 0.0644618 |
| GNE | 0.0644253 |
| CHST4 | 0.0644003 |
| NRD1 | 0.0643802 |
| LCE3E | 0.0643500 |
| SLC2A3 | 0.0643285 |
| WIPF2 | 0.0643234 |
| CLDN23 | 0.0643154 |
| MDC1 | 0.0643110 |
| COMMD1 | 0.0642879 |
| HOXB9 | 0.0642718 |
| PSMD13 | 0.0642656 |
| CMPK1 | 0.0642627 |
| PIP4K2A | 0.0642378 |
| MRPS31 | 0.0641694 |
| ATG7 | 0.0640409 |
| ASCL5 | 0.0639427 |
| APCS | 0.0639217 |
| DOCK10 | 0.0639102 |
| POU4F1 | 0.0638207 |
| RFX5 | 0.0637918 |
| ABCC2 | 0.0637861 |
| NXF3 | 0.0637737 |
| TIMP2 | 0.0637037 |
| CREB5 | 0.0636963 |
| TCP1 | 0.0636829 |
| SLC37A2 | 0.0636587 |
| CDC25C | 0.0636377 |
| NPBWR1 | 0.0636220 |
| MEX3B | 0.0635786 |
| RFC3 | 0.0635713 |
| ISG15 | 0.0635022 |
| RNF114 | 0.0634672 |
| OBP2A | 0.0634576 |
| YAP1 | 0.0634501 |
| G3BP2 | 0.0633575 |
| RCAN3 | 0.0633023 |
| SMIM13 | 0.0632777 |
| SHKBP1 | 0.0632624 |
| KRT85 | 0.0632521 |
| PAQR8 | 0.0632408 |
| CORO7 | 0.0632250 |
| NR4A3 | 0.0632227 |
| TMCC3 | 0.0632060 |
| GSG2 | 0.0631960 |
| CASP6 | 0.0631794 |
| NMT2 | 0.0630666 |
| ATP1B3 | 0.0630623 |
| P2RY10 | 0.0630555 |
| STIL | 0.0630238 |
| MAP1S | 0.0629835 |
| HIST1H2BC | 0.0629775 |
| PITPNM3 | 0.0629752 |
| ARHGAP26 | 0.0629039 |
| SKA1 | 0.0628731 |
| SRPR | 0.0628374 |
| PPP2R3A | 0.0627453 |
| C6orf62 | 0.0627269 |
| OTOF | 0.0626746 |
| TMEM243 | 0.0626578 |
| SYNRG | 0.0626272 |
| BMF | 0.0625832 |
| FAM212B | 0.0625202 |
| EIF3D | 0.0625073 |
| NAA10 | 0.0624918 |
| CDK4 | 0.0624662 |
| TNIP1 | 0.0624546 |
| RPS6KA1 | 0.0624299 |
| DHX16 | 0.0624288 |
| CPNE4 | 0.0624169 |
| CMSS1 | 0.0624080 |
| GPN2 | 0.0623746 |
| DNAJC2 | 0.0623692 |
| UCP3 | 0.0623402 |
| CTU2 | 0.0623252 |
| IL13 | 0.0623010 |
| DUSP14 | 0.0622673 |
| PSMB1 | 0.0622528 |
| MAGT1 | 0.0621829 |
| CTNNBIP1 | 0.0621807 |
| ERLEC1 | 0.0621519 |
| CHORDC1 | 0.0621340 |
| PRMT1 | 0.0621318 |
| MFI2 | 0.0621096 |
| CPPED1 | 0.0620820 |
| ITPKB | 0.0620635 |
| NUP214 | 0.0619599 |
| PRSS12 | 0.0619471 |
| ICOSLG | 0.0619353 |
| REXO4 | 0.0619344 |
| TMEM39B | 0.0619293 |
| HNRNPUL1 | 0.0618763 |
| WEE1 | 0.0618376 |
| ARHGAP44 | 0.0617088 |
| LIG1 | 0.0616734 |
| SLC25A11 | 0.0616425 |
| APMAP | 0.0616052 |
| MFSD9 | 0.0615267 |
| E2F4 | 0.0614567 |
| MRPL12 | 0.0613235 |
| OSGEP | 0.0612656 |
| PSMB7 | 0.0612407 |
| IGFBP3 | 0.0612036 |
| SPINK5 | 0.0611362 |
| ZNF267 | 0.0611328 |
| RAB10 | 0.0611269 |
| LCE5A | 0.0611104 |
| C17orf51 | 0.0610872 |
| MYBBP1A | 0.0610781 |
| ACKR4 | 0.0610548 |
| TMEM258 | 0.0610088 |
| ARHGEF3 | 0.0609713 |
| CCDC134 | 0.0609680 |
| CSNK2B | 0.0608544 |
| TOM1 | 0.0607582 |
| TMEM43 | 0.0607556 |
| TNS3 | 0.0607419 |
| PIP4K2B | 0.0606498 |
| TAS2R31 | 0.0606323 |
| CFDP1 | 0.0605924 |
| SYNE2 | 0.0605894 |
| RPL23 | 0.0605218 |
| APH1A | 0.0605203 |
| RAVER1 | 0.0604600 |
| PDCD1LG2 | 0.0604495 |
| FARS2 | 0.0604362 |
| XPO5 | 0.0604108 |
| AUP1 | 0.0603902 |
| EIF5B | 0.0603693 |
| DUSP12 | 0.0603255 |
| ASCC1 | 0.0603052 |
| SEC14L4 | 0.0600982 |
| PLEKHG2 | 0.0600617 |
| CCDC124 | 0.0600488 |
| WTAP | 0.0600426 |
| CCDC82 | 0.0600253 |
| RQCD1 | 0.0599990 |
| SPDL1 | 0.0599852 |
| SLC16A2 | 0.0598867 |
| RNF220 | 0.0598731 |
| YDJC | 0.0598604 |
| SNF8 | 0.0598394 |
| CDK8 | 0.0598071 |
| HARBI1 | 0.0597933 |
| STX5 | 0.0597550 |
| GREM1 | 0.0597153 |
| BACH1 | 0.0596728 |
| RNF24 | 0.0596459 |
| RBMS2 | 0.0596199 |
| OCIAD2 | 0.0596084 |
| IARS | 0.0595377 |
| PTPRJ | 0.0594832 |
| COL11A2 | 0.0594606 |
| PEX13 | 0.0594144 |
| GSPT2 | 0.0593754 |
| SDE2 | 0.0593437 |
| UPF2 | 0.0593275 |
| SAC3D1 | 0.0593196 |
| NCKAP5L | 0.0592697 |
| NEK2 | 0.0592679 |
| RAB25 | 0.0592277 |
| NUDT3 | 0.0592243 |
| PRKAG3 | 0.0591941 |
| GCHFR | 0.0591698 |
| CTSA | 0.0591694 |
| FLOT2 | 0.0591591 |
| ATAD5 | 0.0591370 |
| SMARCC1 | 0.0591242 |
| KRTCAP2 | 0.0590785 |
| CYB5R3 | 0.0589984 |
| SLC16A11 | 0.0589584 |
| ECE2 | 0.0589545 |
| MRPS21 | 0.0589507 |
| AADAC | 0.0588487 |
| IFNL1 | 0.0587494 |
| PRICKLE1 | 0.0587491 |
| CHPF2 | 0.0587096 |
| DAPK1 | 0.0587081 |
| GLA | 0.0587053 |
| PRMT2 | 0.0586869 |
| CSF2 | 0.0586718 |
| RIPK1 | 0.0586635 |
| PRRT1 | 0.0585530 |
| SPG21 | 0.0584897 |
| CNGA1 | 0.0584851 |
| SLC17A5 | 0.0584370 |
| SCO2 | 0.0584263 |
| EXT2 | 0.0583851 |
| PAGE2 | 0.0583828 |
| PARD3 | 0.0582969 |
| SDHAF1 | 0.0582392 |
| CACNA1A | 0.0582379 |
| UBA2 | 0.0582218 |
| BACH2 | 0.0581974 |
| RNF183 | 0.0581790 |
| VAMP7 | 0.0581515 |
| BTG1 | 0.0580679 |
| GTDC1 | 0.0580604 |
| CNR2 | 0.0579309 |
| JMJD4 | 0.0579202 |
| KIR3DL1 | 0.0579108 |
| ALPK1 | 0.0579099 |
| TRIB2 | 0.0578912 |
| VAC14 | 0.0578680 |
| DNAJC15 | 0.0578619 |
| C12orf5 | 0.0578506 |
| PIPOX | 0.0578480 |
| TNFRSF18 | 0.0578175 |
| TPP1 | 0.0578103 |
| BAG6 | 0.0578055 |
| CARS2 | 0.0577830 |
| HSD17B10 | 0.0577416 |
| ANKRD9 | 0.0577005 |
| FRK | 0.0576646 |
| ADAMTS2 | 0.0576288 |
| KLK11 | 0.0576269 |
| LTK | 0.0576226 |
| SLC52A2 | 0.0576216 |
| MAPRE1 | 0.0576059 |
| MARK1 | 0.0575548 |
| ZNF80 | 0.0574770 |
| FAM83F | 0.0574341 |
| MAP3K6 | 0.0574177 |
| SSU72 | 0.0573717 |
| EVA1A | 0.0573366 |
| GBGT1 | 0.0573171 |
| ZC3H18 | 0.0572193 |
| COX6B1 | 0.0571270 |
| MAG | 0.0571181 |
| CD1C | 0.0571017 |
| C1QBP | 0.0570628 |
| FEM1B | 0.0570501 |
| POLDIP3 | 0.0570392 |
| ZFAND3 | 0.0570350 |
| CDH2 | 0.0570281 |
| AP2S1 | 0.0570274 |
| C6orf136 | 0.0570167 |
| WBSCR22 | 0.0570147 |
| FOXD1 | 0.0569838 |
| DKC1 | 0.0569666 |
| MTMR14 | 0.0568281 |
| CNP | 0.0568102 |
| KRT3 | 0.0567879 |
| BEAN1 | 0.0566998 |
| CENPL | 0.0565714 |
| GINS4 | 0.0565489 |
| SAMD11 | 0.0565338 |
| INTS10 | 0.0564626 |
| PCDHA1 | 0.0564109 |
| GLRX3 | 0.0563416 |
| NUDT21 | 0.0563338 |
| PLK4 | 0.0563316 |
| NUMBL | 0.0563295 |
| MYO1E | 0.0563229 |
| ERI1 | 0.0563046 |
| APEX1 | 0.0563041 |
| UMPS | 0.0562969 |
| FANCI | 0.0562799 |
| CLEC7A | 0.0562685 |
| NSUN2 | 0.0562449 |
| PHF5A | 0.0562286 |
| CD55 | 0.0561986 |
| PDE7A | 0.0561901 |
| EMC6 | 0.0561340 |
| M6PR | 0.0561007 |
| TJP2 | 0.0560622 |
| C11orf73 | 0.0560551 |
| PCNX | 0.0560508 |
| FAM109B | 0.0560488 |
| B3GNT4 | 0.0560461 |
| ADAM10 | 0.0559995 |
| CCSAP | 0.0559622 |
| CDKN1A | 0.0559150 |
| RNF125 | 0.0559145 |
| CEP78 | 0.0558486 |
| SLC25A52 | 0.0557612 |
| RAPH1 | 0.0557606 |
| FOS | 0.0557465 |
| WAC | 0.0557172 |
| PASK | 0.0556764 |
| COX4I1 | 0.0556146 |
| MRGBP | 0.0555540 |
| C6orf57 | 0.0555214 |
| GNG7 | 0.0554809 |
| NLRP2 | 0.0554790 |
| CCDC138 | 0.0554477 |
| SRSF3 | 0.0554109 |
| MEA1 | 0.0553476 |
| RLIM | 0.0553421 |
| PPP1CB | 0.0553412 |
| OR5H1 | 0.0553390 |
| SLC35C2 | 0.0553268 |
| BRCA2 | 0.0553029 |
| ABCA13 | 0.0552896 |
| ADAP2 | 0.0552452 |
| MITD1 | 0.0551506 |
| TMEM102 | 0.0551376 |
| RRH | 0.0551262 |
| SNX17 | 0.0551084 |
| GNG4 | 0.0550815 |
| LPIN2 | 0.0550796 |
| UCK1 | 0.0550660 |
| COPE | 0.0550310 |
| EIF2B3 | 0.0550071 |
| PLEKHG4B | 0.0549267 |
| TMEM106A | 0.0549190 |
| IL17RC | 0.0548921 |
| DND1 | 0.0548675 |
| AP2M1 | 0.0548645 |
| PAX9 | 0.0548574 |
| CHST3 | 0.0548189 |
| LRRC15 | 0.0547902 |
| PACSIN1 | 0.0547260 |
| PPP1R11 | 0.0546884 |
| OCA2 | 0.0546868 |
| POLD1 | 0.0546834 |
| CUL2 | 0.0546829 |
| KBTBD8 | 0.0546661 |
| PLEK2 | 0.0546189 |
| PRPS1 | 0.0545378 |
| OSTM1 | 0.0545260 |
| CHFR | 0.0544598 |
| HCN2 | 0.0544527 |
| NME1 | 0.0544525 |
| LSM4 | 0.0544512 |
| CCDC86 | 0.0544428 |
| PUS7 | 0.0544067 |
| SMCHD1 | 0.0543437 |
| MSH6 | 0.0542971 |
| HIST1H2BH | 0.0542953 |
| TEX2 | 0.0542786 |
| TMBIM1 | 0.0542454 |
| SARS2 | 0.0541882 |
| CCDC69 | 0.0541809 |
| ABCF3 | 0.0540800 |
| LINC00346 | 0.0540661 |
| NIPAL2 | 0.0540565 |
| VPS35 | 0.0540419 |
| RRAS | 0.0540140 |
| TRIM25 | 0.0539698 |
| GLIPR1 | 0.0539627 |
| ZNF146 | 0.0539420 |
| NUP62 | 0.0539283 |
| PARP1 | 0.0539145 |
| POTEF | 0.0539109 |
| ATP5G1 | 0.0539000 |
| MUC16 | 0.0538834 |
| ANKRD54 | 0.0538681 |
| TRDMT1 | 0.0538099 |
| CYP39A1 | 0.0537424 |
| LGALSL | 0.0537273 |
| NCBP1 | 0.0537187 |
| EMILIN1 | 0.0537131 |
| SMC2 | 0.0536872 |
| ARHGEF1 | 0.0536857 |
| MKNK1 | 0.0536683 |
| KCTD20 | 0.0536425 |
| DSN1 | 0.0536148 |
| ZNF286A | 0.0534987 |
| SEMA4D | 0.0534872 |
| MMD | 0.0534429 |
| SRF | 0.0534298 |
| GTF2H4 | 0.0533540 |
| PAFAH1B1 | 0.0533157 |
| HEXB | 0.0533049 |
| PYCR1 | 0.0532679 |
| TLR10 | 0.0532178 |
| ATP11B | 0.0532032 |
| DIAPH1 | 0.0532024 |
| CFI | 0.0531399 |
| PLXNB2 | 0.0531227 |
| COX6A2 | 0.0530836 |
| CPZ | 0.0530594 |
| CENPI | 0.0530484 |
| SIRPB2 | 0.0530232 |
| ACTN2 | 0.0529815 |
| TPD52L2 | 0.0529670 |
| PATL1 | 0.0529487 |
| ADAT2 | 0.0528492 |
| CLCN5 | 0.0528477 |
| HSPBAP1 | 0.0528466 |
| BPGM | 0.0528452 |
| ELAC2 | 0.0528400 |
| ARHGEF9 | 0.0528387 |
| IDH3G | 0.0527871 |
| IL17C | 0.0527859 |
| LAS1L | 0.0527541 |
| OSMR | 0.0527296 |
| NEIL3 | 0.0527172 |
| ARPC1A | 0.0526923 |
| TOR2A | 0.0526893 |
| ATG3 | 0.0526754 |
| COMTD1 | 0.0526751 |
| PDXP | 0.0526447 |
| FAM178B | 0.0526308 |
| CSF2RB | 0.0526227 |
| DYRK2 | 0.0526161 |
| TGFBR1 | 0.0525721 |
| DDX43 | 0.0525528 |
| FN1 | 0.0525000 |
| GPX1 | 0.0524325 |
| LPAR5 | 0.0523777 |
| MYH14 | 0.0523581 |
| CLMP | 0.0523217 |
| MUC3A | 0.0523151 |
| PRKCDBP | 0.0522296 |
| MAPKAP1 | 0.0521385 |
| SNRPD1 | 0.0520900 |
| KCNAB2 | 0.0520477 |
| MYCL | 0.0520193 |
| PCYT1A | 0.0520019 |
| CARS | 0.0519884 |
| RIN3 | 0.0519663 |
| ATG4A | 0.0519596 |
| SHFM1 | 0.0518972 |
| PI4KB | 0.0518832 |
| ATP6V0D1 | 0.0518814 |
| EWSR1 | 0.0518610 |
| CBR1 | 0.0518598 |
| MIS12 | 0.0518509 |
| OLFM2 | 0.0518392 |
| CSF3R | 0.0518269 |
| EGFR | 0.0517282 |
| MIF | 0.0516977 |
| C11orf71 | 0.0516786 |
| HSF2 | 0.0516337 |
| DYRK4 | 0.0515543 |
| SETD6 | 0.0515386 |
| SNRPF | 0.0515198 |
| SOCS7 | 0.0514792 |
| SLC25A1 | 0.0514537 |
| AIFM1 | 0.0513891 |
| MME | 0.0513553 |
| PGM2L1 | 0.0513430 |
| PTPRF | 0.0513214 |
| MPDU1 | 0.0513002 |
| MCM8 | 0.0512991 |
| RACGAP1 | 0.0512189 |
| NOL12 | 0.0512091 |
| BOP1 | 0.0511970 |
| SUCLG1 | 0.0511754 |
| VMP1 | 0.0511727 |
| SLFN12 | 0.0511626 |
| C2orf43 | 0.0511577 |
| BRPF1 | 0.0511560 |
| RLF | 0.0511509 |
| GADD45B | 0.0511465 |
| UBE2Q1 | 0.0511269 |
| B4GALT1 | 0.0511179 |
| AREL1 | 0.0510872 |
| RNF19B | 0.0510803 |
| ZSCAN16 | 0.0510285 |
| PMCH | 0.0510144 |
| IL12A | 0.0510128 |
| GSTK1 | 0.0509233 |
| IL13RA1 | 0.0508951 |
| PAICS | 0.0508202 |
| SLC2A9 | 0.0508104 |
| UGT1A6 | 0.0506846 |
| ADM2 | 0.0506650 |
| STT3B | 0.0506635 |
| L3MBTL2 | 0.0506491 |
| ZNF93 | 0.0506435 |
| PRNP | 0.0506369 |
| RPS25 | 0.0506288 |
| ALDH1A1 | 0.0505984 |
| IRF3 | 0.0505963 |
| TMEM180 | 0.0505576 |
| PCSK7 | 0.0505169 |
| USO1 | 0.0505037 |
| SIRT7 | 0.0505002 |
| RHBDD3 | 0.0504692 |
| CEACAM21 | 0.0504453 |
| IDO2 | 0.0504322 |
| HTRA2 | 0.0504074 |
| TIAL1 | 0.0504013 |
| DCK | 0.0503833 |
| SNRPC | 0.0503530 |
| FAM84A | 0.0503462 |
| TP53I13 | 0.0503316 |
| WDR74 | 0.0502971 |
| TMEM239 | 0.0502817 |
| TCIRG1 | 0.0502692 |
| GJB5 | 0.0502609 |
| ANKRD13A | 0.0502350 |
| ESCO2 | 0.0501746 |
| HNRNPL | 0.0501664 |
| GSK3B | 0.0501602 |
| DBNL | 0.0501573 |
| WWC3 | 0.0501449 |
| SPATC1L | 0.0501415 |
| MAP1LC3B | 0.0501302 |
| MFHAS1 | 0.0501070 |
| PSMC3 | 0.0500768 |
| ITGA5 | 0.0500636 |
| FAM181A | 0.0500379 |
| SCHIP1 | 0.0499758 |
| LEMD2 | 0.0499687 |
| RASL10A | 0.0499394 |
| HRASLS5 | 0.0499196 |
| C14orf1 | 0.0499075 |
| AP3S1 | 0.0498994 |
| HNRNPA2B1 | 0.0498529 |
| AKIRIN1 | 0.0498162 |
| HOXA3 | 0.0497674 |
| SDHAF2 | 0.0497528 |
| BAZ1B | 0.0497131 |
| TLR7 | 0.0497067 |
| C11orf21 | 0.0497006 |
| NGLY1 | 0.0496578 |
| ZWILCH | 0.0496573 |
| CRYGA | 0.0496294 |
| ACLY | 0.0495687 |
| NRG2 | 0.0495192 |
| SPINK7 | 0.0494637 |
| RHEB | 0.0494365 |
| SLC12A1 | 0.0493751 |
| AKAP2 | 0.0493691 |
| PPIAL4G | 0.0493619 |
| JPH2 | 0.0493471 |
| KDM2A | 0.0493221 |
| INPP1 | 0.0492993 |
| CYP2J2 | 0.0492966 |
| REXO2 | 0.0492844 |
| NAA11 | 0.0492743 |
| TXK | 0.0492612 |
| PLAGL1 | 0.0492450 |
| POGK | 0.0492234 |
| TRIM10 | 0.0491900 |
| ARCN1 | 0.0491580 |
| IFITM5 | 0.0490909 |
| GK | 0.0490525 |
| ACSS1 | 0.0490441 |
| TFEB | 0.0489980 |
| CEBPE | 0.0489818 |
| C19orf48 | 0.0489729 |
| TAOK3 | 0.0489343 |
| SIVA1 | 0.0489205 |
| FAM129C | 0.0488735 |
| DLG4 | 0.0488667 |
| E2F5 | 0.0488403 |
| ANKRD27 | 0.0488251 |
| PNPLA3 | 0.0488205 |
| MARK2 | 0.0488184 |
| CENPQ | 0.0488177 |
| ANKRD11 | 0.0487804 |
| FN3KRP | 0.0487802 |
| PPIAL4B | 0.0487722 |
| PRDM8 | 0.0487590 |
| IAPP | 0.0487440 |
| C1orf228 | 0.0487378 |
| GRAMD2 | 0.0487189 |
| GRAMD3 | 0.0487105 |
| TAOK1 | 0.0486993 |
| SUPT20H | 0.0486679 |
| TIMM10 | 0.0486623 |
| MARVELD3 | 0.0486209 |
| MBNL2 | 0.0486115 |
| SLC11A2 | 0.0486069 |
| TMEM164 | 0.0485978 |
| SRC | 0.0485448 |
| NELFE | 0.0485304 |
| FIGNL1 | 0.0485149 |
| ARHGAP18 | 0.0485124 |
| SLC19A1 | 0.0484865 |
| FOXN3 | 0.0483674 |
| LRR1 | 0.0483575 |
| GFRA4 | 0.0482774 |
| KRTAP13-4 | 0.0482486 |
| FOXRED1 | 0.0482426 |
| PRR5 | 0.0482350 |
| DUX4L4 | 0.0482310 |
| ADAT3 | 0.0482283 |
| C16orf3 | 0.0482149 |
| PRPF4 | 0.0481946 |
| ULBP2 | 0.0480744 |
| MAP3K9 | 0.0480523 |
| CRTC2 | 0.0480511 |
| TREM2 | 0.0479915 |
| CNOT1 | 0.0479798 |
| NMRK1 | 0.0479406 |
| NRM | 0.0479157 |
| SLC22A2 | 0.0478544 |
| DYNLT1 | 0.0478475 |
| BICD2 | 0.0478108 |
| TRIM38 | 0.0477614 |
| SNTB1 | 0.0477277 |
| SMPD2 | 0.0477223 |
| CDC26 | 0.0476917 |
| PANX3 | 0.0476363 |
| HIST1H3G | 0.0475962 |
| CHIA | 0.0475740 |
| DUSP15 | 0.0475704 |
| CD300C | 0.0475412 |
| FANCB | 0.0475102 |
| NUDT1 | 0.0474638 |
| CNOT11 | 0.0474288 |
| CEP57 | 0.0474115 |
| CKAP5 | 0.0473831 |
| LIMK1 | 0.0473137 |
| UBASH3B | 0.0472127 |
| NUDT15 | 0.0471983 |
| MUC6 | 0.0471841 |
| FADS1 | 0.0471829 |
| ARHGEF4 | 0.0471714 |
| FAM127B | 0.0471598 |
| ZDHHC14 | 0.0471452 |
| PFDN6 | 0.0471189 |
| VPS54 | 0.0470954 |
| SIGLEC8 | 0.0470716 |
| RNF113A | 0.0470680 |
| F13A1 | 0.0470606 |
| TADA2A | 0.0470525 |
| CDR2L | 0.0470296 |
| TSACC | 0.0470222 |
| MTF2 | 0.0470183 |
| PRPF31 | 0.0470132 |
| MTM1 | 0.0469864 |
| SLC9A7 | 0.0469367 |
| CDK5RAP2 | 0.0468913 |
| GNA12 | 0.0468880 |
| HIST1H2BI | 0.0468873 |
| TUBGCP3 | 0.0468844 |
| PDCL | 0.0468596 |
| SURF6 | 0.0468530 |
| PRKRIR | 0.0468438 |
| CERK | 0.0468370 |
| LGALS3BP | 0.0468019 |
| TGFBR2 | 0.0467270 |
| PLCG1 | 0.0466698 |
| VSX1 | 0.0466403 |
| VPS33A | 0.0466040 |
| AKT1 | 0.0466013 |
| APEX2 | 0.0465986 |
| SRD5A3 | 0.0465115 |
| MEST | 0.0464690 |
| C19orf43 | 0.0464394 |
| XPNPEP2 | 0.0463949 |
| DCST2 | 0.0463601 |
| WDR76 | 0.0463225 |
| DENND6B | 0.0463192 |
| C17orf59 | 0.0463000 |
| CSNK1G2 | 0.0462550 |
| CHAMP1 | 0.0462290 |
| KDM2B | 0.0462032 |
| PARVB | 0.0460888 |
| MDFIC | 0.0460626 |
| SMEK1 | 0.0460584 |
| NUPR1 | 0.0460136 |
| HBEGF | 0.0459876 |
| B4GALT2 | 0.0459553 |
| ACVRL1 | 0.0459489 |
| DNAJC22 | 0.0459414 |
| MOV10 | 0.0459319 |
| ARHGAP31 | 0.0459281 |
| RASAL2 | 0.0458865 |
| NEDD9 | 0.0458683 |
| DERA | 0.0457692 |
| TBCCD1 | 0.0457637 |
| ZBED4 | 0.0456541 |
| DROSHA | 0.0456444 |
| CDK5R1 | 0.0456253 |
| IL9R | 0.0455842 |
| MOG | 0.0455713 |
| BNIP3 | 0.0454857 |
| MAP3K11 | 0.0453988 |
| PAFAH1B2 | 0.0453821 |
| ARID3A | 0.0453750 |
| SPP1 | 0.0453671 |
| SPAG9 | 0.0453615 |
| ACR | 0.0453603 |
| TMPO | 0.0453523 |
| TOP3B | 0.0452844 |
| POLR1E | 0.0452698 |
| OTUB1 | 0.0452390 |
| MPHOSPH10 | 0.0452372 |
| MKRN2 | 0.0452057 |
| CEP72 | 0.0451852 |
| IP6K1 | 0.0451638 |
| SNX12 | 0.0451564 |
| GPR97 | 0.0451392 |
| TRPV4 | 0.0451042 |
| MTFR1 | 0.0450986 |
| XRN1 | 0.0450713 |
| OR6M1 | 0.0450331 |
| TIGD1 | 0.0449737 |
| OR52K2 | 0.0449663 |
| GAREML | 0.0449357 |
| STARD5 | 0.0449310 |
| MBNL1 | 0.0449287 |
| STK19 | 0.0449286 |
| UBA52 | 0.0449274 |
| DPM1 | 0.0449100 |
| TNPO3 | 0.0448678 |
| TST | 0.0448607 |
| GEMIN7 | 0.0448536 |
| ERCC2 | 0.0448138 |
| C9orf69 | 0.0448126 |
| IFT20 | 0.0447916 |
| AOX1 | 0.0447669 |
| GPR174 | 0.0447106 |
| RASA2 | 0.0446763 |
| ARHGEF39 | 0.0446648 |
| MAP7D3 | 0.0446315 |
| PVR | 0.0446183 |
| TMEM14C | 0.0445295 |
| OIP5 | 0.0443508 |
| GTF3A | 0.0443500 |
| SLC7A6 | 0.0443003 |
| ADCY3 | 0.0442946 |
| ARL6IP5 | 0.0442863 |
| TAS2R9 | 0.0442774 |
| CCNL1 | 0.0442764 |
| WRNIP1 | 0.0442306 |
| EGR1 | 0.0441934 |
| NME2 | 0.0441881 |
| YIPF2 | 0.0441779 |
| RPA1 | 0.0441601 |
| DNAJC3 | 0.0441570 |
| OGDHL | 0.0441231 |
| TMEM70 | 0.0440905 |
| FOXH1 | 0.0440710 |
| NPB | 0.0440629 |
| UBE2S | 0.0440625 |
| SLAMF6 | 0.0440125 |
| KRT72 | 0.0439136 |
| SSBP1 | 0.0439080 |
| C11orf42 | 0.0438865 |
| BCL3 | 0.0438686 |
| HDDC2 | 0.0438588 |
| CHRM4 | 0.0438566 |
| PLEKHM2 | 0.0438566 |
| EIF2S1 | 0.0438487 |
| TMPRSS3 | 0.0438207 |
| TMEM60 | 0.0437830 |
| CTAG2 | 0.0436638 |
| VGLL3 | 0.0436636 |
| MTMR12 | 0.0436590 |
| EPB41L4B | 0.0436519 |
| MYO1A | 0.0436381 |
| MAFA | 0.0436358 |
| CLN6 | 0.0436210 |
| UBE2Z | 0.0436130 |
| ZC3HAV1 | 0.0435846 |
| LMAN1L | 0.0435785 |
| NLRP1 | 0.0435620 |
| GINS3 | 0.0435333 |
| MAPKAPK3 | 0.0435118 |
| HTATSF1 | 0.0435054 |
| NOLC1 | 0.0434949 |
| TEFM | 0.0434659 |
| COLCA2 | 0.0434569 |
| SAP25 | 0.0434434 |
| SART1 | 0.0434104 |
| XCR1 | 0.0433847 |
| NF2 | 0.0433706 |
| RLTPR | 0.0433659 |
| GPR137B | 0.0433402 |
| PPP1R15A | 0.0433115 |
| SLC25A18 | 0.0432571 |
| PPM1D | 0.0432524 |
| DDA1 | 0.0432069 |
| DDX1 | 0.0431687 |
| RAB1A | 0.0431512 |
| TOMM70A | 0.0431413 |
| TXNIP | 0.0431175 |
| CTSK | 0.0431069 |
| DNASE1L3 | 0.0430837 |
| NPAS2 | 0.0430317 |
| GPR87 | 0.0429942 |
| CACNB3 | 0.0429919 |
| SLC22A31 | 0.0429624 |
| KXD1 | 0.0429566 |
| AGPAT2 | 0.0429272 |
| CASP2 | 0.0428553 |
| FFAR2 | 0.0428457 |
| GPR25 | 0.0428118 |
| GPC6 | 0.0427486 |
| TALDO1 | 0.0427418 |
| SETMAR | 0.0427293 |
| GPS1 | 0.0427016 |
| DTNA | 0.0426464 |
| ZYG11A | 0.0425919 |
| UBE4A | 0.0425786 |
| MAP2K6 | 0.0425095 |
| MAT2B | 0.0425016 |
| RHOF | 0.0424861 |
| MANEA | 0.0424489 |
| PLOD3 | 0.0424140 |
| C11orf84 | 0.0424093 |
| NUSAP1 | 0.0424036 |
| PSMC1 | 0.0423976 |
| GPBP1L1 | 0.0423132 |
| PAK6 | 0.0422794 |
| CAPZA1 | 0.0422360 |
| TMEM173 | 0.0421778 |
| IPO5 | 0.0421525 |
| STYK1 | 0.0420907 |
| PDCD11 | 0.0420633 |
| INHBC | 0.0419993 |
| NPM2 | 0.0419922 |
| DLG1 | 0.0419917 |
| ZEB2 | 0.0419716 |
| MOB3C | 0.0419451 |
| GPR155 | 0.0419193 |
| UGT2B11 | 0.0418860 |
| MKL1 | 0.0418830 |
| TBKBP1 | 0.0418624 |
| ARRDC5 | 0.0418587 |
| PPP1R9B | 0.0418464 |
| ARID1B | 0.0418310 |
| MOB3B | 0.0417850 |
| RXRB | 0.0417747 |
| TMEM156 | 0.0417583 |
| RPL35 | 0.0417426 |
| ZNF124 | 0.0417372 |
| UQCC2 | 0.0417125 |
| ITPA | 0.0417094 |
| STK25 | 0.0416970 |
| ZDHHC12 | 0.0416930 |
| ST8SIA4 | 0.0416185 |
| ZBTB5 | 0.0416176 |
| SLC37A3 | 0.0415794 |
| MORC1 | 0.0415679 |
| AK2 | 0.0415632 |
| DFFA | 0.0415308 |
| RNF38 | 0.0415274 |
| FETUB | 0.0414937 |
| MBD4 | 0.0414536 |
| TMEM210 | 0.0413593 |
| IL1RAP | 0.0413036 |
| ADPRH | 0.0412563 |
| SGPL1 | 0.0412360 |
| DOHH | 0.0412273 |
| CSDE1 | 0.0412267 |
| PAQR4 | 0.0411938 |
| IER5 | 0.0411883 |
| ZBTB7B | 0.0411400 |
| ARSF | 0.0411305 |
| HUWE1 | 0.0411185 |
| ELL | 0.0410903 |
| WDFY1 | 0.0410522 |
| NUP160 | 0.0410507 |
| ARL5A | 0.0410217 |
| TMEM163 | 0.0409869 |
| CCDC47 | 0.0409682 |
| PEA15 | 0.0409459 |
| MST4 | 0.0409321 |
| CASP8 | 0.0408884 |
| WDR81 | 0.0408596 |
| DIRAS1 | 0.0407693 |
| MSR1 | 0.0407687 |
| C1orf229 | 0.0407418 |
| ATR | 0.0407125 |
| HEATR1 | 0.0406963 |
| YIF1A | 0.0406539 |
| H6PD | 0.0406291 |
| SLC44A2 | 0.0406280 |
| IGF2BP1 | 0.0405951 |
| MAP3K3 | 0.0405846 |
| CAPNS2 | 0.0405587 |
| NOTCH2 | 0.0405404 |
| CSNK2A2 | 0.0405211 |
| LILRA1 | 0.0404908 |
| SLCO5A1 | 0.0404830 |
| MMP15 | 0.0404818 |
| TMEM37 | 0.0404515 |
| C6orf52 | 0.0404313 |
| PRKCI | 0.0404123 |
| KLRG1 | 0.0403811 |
| ATP5J2 | 0.0403285 |
| LMTK2 | 0.0403276 |
| ZNF672 | 0.0403233 |
| EXOC3L1 | 0.0402904 |
| IYD | 0.0402628 |
| CCZ1 | 0.0402388 |
| SLC6A9 | 0.0402057 |
| SLC4A1AP | 0.0401948 |
| DHX37 | 0.0401944 |
| GMEB1 | 0.0401415 |
| KLK9 | 0.0400429 |
| TRAF3 | 0.0400142 |
| PSMC5 | 0.0399759 |
| SLC30A2 | 0.0399632 |
| HOXC12 | 0.0399583 |
| PSMA6 | 0.0399300 |
| RFWD2 | 0.0398930 |
| MRPL19 | 0.0398387 |
| GABRA3 | 0.0398297 |
| PRPF19 | 0.0397642 |
| C2orf88 | 0.0397367 |
| NOP16 | 0.0397179 |
| ENSA | 0.0396879 |
| PPIAL4A | 0.0396471 |
| KDM5A | 0.0395963 |
| ELANE | 0.0395239 |
| EXT1 | 0.0394746 |
| N4BP2L1 | 0.0394630 |
| HAUS7 | 0.0394556 |
| MAL2 | 0.0393761 |
| SPRR1B | 0.0393269 |
| CCDC166 | 0.0393245 |
| SLC35D2 | 0.0393132 |
| CKAP2 | 0.0393114 |
| RAB5A | 0.0393002 |
| ZFP36L1 | 0.0392925 |
| PRADC1 | 0.0392731 |
| RPS6 | 0.0392591 |
| GBP6 | 0.0392025 |
| FASTKD5 | 0.0391942 |
| XRCC5 | 0.0391704 |
| SPATS2 | 0.0391671 |
| CCDC80 | 0.0391667 |
| TMLHE | 0.0391505 |
| SAP30BP | 0.0391394 |
| MSRB1 | 0.0391246 |
| CCDC3 | 0.0391149 |
| CCDC23 | 0.0390978 |
| KIAA0922 | 0.0390798 |
| SERTAD4 | 0.0390734 |
| PPIH | 0.0390476 |
| RCN2 | 0.0390222 |
| ZNF362 | 0.0389943 |
| DAZAP1 | 0.0389887 |
| TTF1 | 0.0389865 |
| SDHB | 0.0389551 |
| ZIC1 | 0.0389035 |
| DPEP1 | 0.0389008 |
| NELFCD | 0.0388863 |
| CLEC4C | 0.0388737 |
| ATAD3B | 0.0388595 |
| PCGF6 | 0.0388511 |
| NKX2-2 | 0.0388445 |
| EIF4EBP1 | 0.0388422 |
| NOP56 | 0.0388407 |
| COL22A1 | 0.0388368 |
| DCBLD1 | 0.0388253 |
| PIK3AP1 | 0.0388211 |
| ANGPTL6 | 0.0388123 |
| HMX2 | 0.0387924 |
| ITGA8 | 0.0387801 |
| NOP9 | 0.0387701 |
| ATP5G3 | 0.0387503 |
| CC2D1B | 0.0387174 |
| SLC6A12 | 0.0387108 |
| SLC1A4 | 0.0386589 |
| HELZ2 | 0.0386482 |
| HAX1 | 0.0386381 |
| CABLES2 | 0.0386035 |
| MATN4 | 0.0385995 |
| RCCD1 | 0.0385845 |
| ABHD17A | 0.0385731 |
| BMP5 | 0.0385614 |
| ATP2A3 | 0.0384784 |
| ZNF574 | 0.0384691 |
| CRB3 | 0.0384681 |
| MMP25 | 0.0384321 |
| HDGFRP2 | 0.0384019 |
| SH2D3A | 0.0383920 |
| CDV3 | 0.0383635 |
| C1orf174 | 0.0383482 |
| POLG | 0.0383149 |
| RPS6KB2 | 0.0383111 |
| TOP3A | 0.0382806 |
| DMRTC2 | 0.0382425 |
| PLCXD1 | 0.0382363 |
| ORC2 | 0.0382242 |
| MTX1 | 0.0382229 |
| DTNB | 0.0382211 |
| KCNK7 | 0.0381751 |
| ANO10 | 0.0381419 |
| GOLPH3 | 0.0381244 |
| APOBR | 0.0380896 |
| SSTR3 | 0.0380858 |
| XK | 0.0380434 |
| FYTTD1 | 0.0380305 |
| RRAGC | 0.0380055 |
| PSMD5 | 0.0380038 |
| TMEM110 | 0.0379564 |
| JUN | 0.0379197 |
| ARHGAP17 | 0.0379188 |
| EXOSC7 | 0.0379185 |
| MYH7 | 0.0379035 |
| CCKBR | 0.0378941 |
| MEX3C | 0.0378849 |
| SSNA1 | 0.0378736 |
| FICD | 0.0378675 |
| SLC16A8 | 0.0378377 |
| DPYD | 0.0378301 |
| TMC6 | 0.0377913 |
| KCTD7 | 0.0377880 |
| SPC24 | 0.0377519 |
| SLC25A37 | 0.0377115 |
| HDHD1 | 0.0377056 |
| WIPF3 | 0.0376776 |
| BRD7 | 0.0376744 |
| ESYT1 | 0.0376712 |
| AHSG | 0.0376602 |
| CDK5R2 | 0.0376542 |
| DAXX | 0.0376510 |
| N4BP1 | 0.0376322 |
| GDAP2 | 0.0376017 |
| THEG | 0.0376016 |
| WASF1 | 0.0375239 |
| C20orf196 | 0.0375232 |
| FMO3 | 0.0374121 |
| RPL35A | 0.0373939 |
| XPO1 | 0.0373597 |
| CDCA4 | 0.0373506 |
| TFB1M | 0.0373404 |
| SLC3A2 | 0.0373043 |
| KIF22 | 0.0372962 |
| NAGA | 0.0372826 |
| LSM7 | 0.0372580 |
| KCTD15 | 0.0372323 |
| DPH7 | 0.0371913 |
| XIRP1 | 0.0371867 |
| CIT | 0.0371761 |
| SH3TC1 | 0.0371674 |
| NIPSNAP3A | 0.0371649 |
| RALA | 0.0371447 |
| GINS2 | 0.0371447 |
| USP28 | 0.0371411 |
| TTC27 | 0.0370984 |
| USP39 | 0.0370871 |
| BLOC1S5 | 0.0370539 |
| SELK | 0.0370302 |
| TMEM184B | 0.0370246 |
| OXNAD1 | 0.0370140 |
| DNAH11 | 0.0370075 |
| RNMTL1 | 0.0369906 |
| FAM57A | 0.0369887 |
| BCL2L11 | 0.0369548 |
| CITED2 | 0.0369249 |
| MRPL27 | 0.0368408 |
| C22orf39 | 0.0368175 |
| SERPINB1 | 0.0368033 |
| DBF4 | 0.0367924 |
| PPARA | 0.0367589 |
| PSRC1 | 0.0367581 |
| KIF1B | 0.0367517 |
| L3HYPDH | 0.0367187 |
| COG4 | 0.0366622 |
| BAIAP2L1 | 0.0366490 |
| VASH2 | 0.0365785 |
| ATP2C2 | 0.0365548 |
| CLK3 | 0.0365182 |
| KRTAP6-3 | 0.0365140 |
| SGMS2 | 0.0364940 |
| EGLN1 | 0.0364925 |
| NKAPL | 0.0364870 |
| SPATS2L | 0.0364702 |
| MGME1 | 0.0364576 |
| PSMA2 | 0.0364506 |
| IRAK3 | 0.0364036 |
| MFRP | 0.0363995 |
| UBA7 | 0.0363826 |
| KCNA5 | 0.0363623 |
| SH2D3C | 0.0363614 |
| MYL12B | 0.0363399 |
| NIT1 | 0.0363063 |
| C2orf47 | 0.0363033 |
| RCAN2 | 0.0361803 |
| FOXP4 | 0.0361522 |
| TRPV5 | 0.0361393 |
| SOX4 | 0.0361286 |
| GATAD2A | 0.0360884 |
| ZFP42 | 0.0360664 |
| TM6SF1 | 0.0360137 |
| DNAJC4 | 0.0359927 |
| DAZL | 0.0359532 |
| CDCP2 | 0.0359412 |
| IRX2 | 0.0358693 |
| MTCH1 | 0.0358335 |
| CYB561 | 0.0357949 |
| ACO2 | 0.0357734 |
| SDC3 | 0.0357500 |
| EIF2AK2 | 0.0357278 |
| FCRL4 | 0.0357256 |
| BMS1 | 0.0357067 |
| HIST1H2AL | 0.0356977 |
| CLC | 0.0356746 |
| SSR3 | 0.0356437 |
| MGAT4B | 0.0355992 |
| HELB | 0.0355534 |
| CH25H | 0.0355170 |
| COQ9 | 0.0354850 |
| LMO2 | 0.0354773 |
| CPXM1 | 0.0354626 |
| MAPK7 | 0.0354553 |
| GNA15 | 0.0354403 |
| INPP5K | 0.0354264 |
| MPV17L2 | 0.0354108 |
| DCLRE1C | 0.0353899 |
| TNFAIP1 | 0.0353836 |
| CYorf17 | 0.0353827 |
| WDR45B | 0.0353822 |
| OXT | 0.0353205 |
| OR3A3 | 0.0352962 |
| CENPJ | 0.0352791 |
| DDX52 | 0.0352723 |
| WDR62 | 0.0352669 |
| TFPI | 0.0352279 |
| TNFSF9 | 0.0351826 |
| FKBPL | 0.0351709 |
| ASB16 | 0.0351573 |
| RAP2B | 0.0351439 |
| KHDRBS3 | 0.0351215 |
| ELOVL3 | 0.0351162 |
| SLC12A8 | 0.0350872 |
| NOP58 | 0.0350029 |
| RGPD1 | 0.0349729 |
| ISY1 | 0.0349404 |
| TSPAN4 | 0.0349357 |
| RBM26 | 0.0348452 |
| CDC40 | 0.0348452 |
| TRAPPC1 | 0.0348442 |
| NGF | 0.0348376 |
| MTMR2 | 0.0347799 |
| AARS2 | 0.0347374 |
| SMIM8 | 0.0347261 |
| KCNK13 | 0.0347173 |
| CHCHD4 | 0.0346977 |
| TMEM39A | 0.0346898 |
| LRWD1 | 0.0346749 |
| MAD2L1BP | 0.0346748 |
| SZT2 | 0.0346683 |
| R3HDM4 | 0.0346434 |
| SEC63 | 0.0346408 |
| C19orf73 | 0.0346139 |
| MUTYH | 0.0346083 |
| GP9 | 0.0345958 |
| SCAMP3 | 0.0345853 |
| CLDN6 | 0.0345812 |
| STX8 | 0.0345745 |
| AEN | 0.0345497 |
| EXD1 | 0.0345468 |
| CEL | 0.0345142 |
| CD81 | 0.0345064 |
| IER5L | 0.0344978 |
| SETD8 | 0.0344822 |
| RPRM | 0.0344507 |
| OAS3 | 0.0344264 |
| ERI3 | 0.0344133 |
| VWA1 | 0.0343690 |
| DEDD2 | 0.0343534 |
| STRA13 | 0.0343390 |
| RPL24 | 0.0343315 |
| DLL3 | 0.0343129 |
| CSE1L | 0.0342906 |
| POP7 | 0.0342687 |
| EHD4 | 0.0341739 |
| QSOX2 | 0.0341703 |
| TMEM97 | 0.0341507 |
| SERPINH1 | 0.0341392 |
| CHMP1A | 0.0340571 |
| XG | 0.0340115 |
| OXER1 | 0.0340027 |
| UFM1 | 0.0339614 |
| PDE3B | 0.0339495 |
| CHST5 | 0.0339341 |
| FAM189B | 0.0339093 |
| AMMECR1 | 0.0338812 |
| PAX8 | 0.0338454 |
| FFAR4 | 0.0338418 |
| EXOSC1 | 0.0337376 |
| ZP1 | 0.0336655 |
| HOPX | 0.0336626 |
| NOC3L | 0.0336606 |
| GRB2 | 0.0336427 |
| LTA4H | 0.0336231 |
| STIM1 | 0.0336159 |
| ITGAE | 0.0336152 |
| TPRKB | 0.0336139 |
| NDUFS6 | 0.0336061 |
| BMP1 | 0.0336047 |
| CDC16 | 0.0335714 |
| DNAJC5 | 0.0335366 |
| GALNS | 0.0335318 |
| COX10 | 0.0335297 |
| TNFRSF1A | 0.0335021 |
| HIST1H2BO | 0.0334697 |
| PELP1 | 0.0334138 |
| FBRSL1 | 0.0333932 |
| SPECC1 | 0.0333802 |
| MID1IP1 | 0.0333784 |
| PITPNC1 | 0.0333249 |
| BEST2 | 0.0333195 |
| NINJ2 | 0.0332746 |
| FUT5 | 0.0332733 |
| ZHX2 | 0.0332394 |
| FILIP1L | 0.0332349 |
| KRTAP10-10 | 0.0332348 |
| RBP5 | 0.0332318 |
| EXOSC5 | 0.0332224 |
| ZNF384 | 0.0331331 |
| UQCR10 | 0.0331261 |
| CLMN | 0.0331096 |
| MCMBP | 0.0330559 |
| CXXC1 | 0.0330307 |
| BCL2L15 | 0.0330228 |
| FAM91A1 | 0.0330127 |
| GPR142 | 0.0329916 |
| PTPN12 | 0.0329540 |
| RAPGEF1 | 0.0329195 |
| DTD1 | 0.0329003 |
| ZSCAN1 | 0.0328976 |
| TWIST2 | 0.0328469 |
| KTI12 | 0.0328054 |
| RASA3 | 0.0328011 |
| CDKN2C | 0.0327590 |
| KRTAP5-9 | 0.0327411 |
| SOHLH1 | 0.0327254 |
| UGGT1 | 0.0327191 |
| C9orf78 | 0.0327059 |
| RNMT | 0.0326345 |
| SIGLEC5 | 0.0326029 |
| SUPV3L1 | 0.0325272 |
| MAGEA10 | 0.0325268 |
| SDCBP | 0.0324664 |
| GPR176 | 0.0324585 |
| ZIC5 | 0.0324571 |
| SETD3 | 0.0324462 |
| STX3 | 0.0324398 |
| C18orf8 | 0.0324392 |
| WDR93 | 0.0323902 |
| PRIM1 | 0.0323771 |
| GPX3 | 0.0323221 |
| BRMS1L | 0.0323094 |
| EPS8L3 | 0.0323076 |
| PCCB | 0.0322638 |
| MRPS33 | 0.0322426 |
| GLRX2 | 0.0322079 |
| ACRC | 0.0322004 |
| LYPD1 | 0.0321899 |
| DNAJA1 | 0.0321286 |
| NDUFS1 | 0.0321238 |
| KRTAP2-1 | 0.0321151 |
| GJB7 | 0.0320985 |
| HEATR3 | 0.0320976 |
| IQSEC3 | 0.0320913 |
| PTGER2 | 0.0320428 |
| ENTPD2 | 0.0320315 |
| ACTL6B | 0.0320272 |
| KCNJ5 | 0.0320205 |
| SFTPB | 0.0319476 |
| ZNF787 | 0.0319096 |
| TMEM175 | 0.0319044 |
| MDH1 | 0.0318823 |
| HIST1H3C | 0.0318617 |
| GPX5 | 0.0318503 |
| L3MBTL3 | 0.0318275 |
| LSM14A | 0.0318125 |
| EI24 | 0.0317721 |
| SYT12 | 0.0317504 |
| CHCHD2 | 0.0317425 |
| CAPNS1 | 0.0317294 |
| TSPAN14 | 0.0317275 |
| ZNF670 | 0.0316857 |
| ZNRF1 | 0.0316789 |
| SRP68 | 0.0316607 |
| ZNF710 | 0.0316217 |
| ERCC6 | 0.0316027 |
| RBL1 | 0.0315952 |
| CACYBP | 0.0315908 |
| GTPBP4 | 0.0315611 |
| EID3 | 0.0315415 |
| UNC5A | 0.0315327 |
| MRPL16 | 0.0315238 |
| C1QL2 | 0.0315042 |
| PACS1 | 0.0314979 |
| MFAP3L | 0.0314469 |
| AQP2 | 0.0314365 |
| NCOA3 | 0.0314320 |
| PEX26 | 0.0314283 |
| HIST2H3D | 0.0313943 |
| C1QTNF2 | 0.0313823 |
| RBX1 | 0.0313622 |
| LIPF | 0.0313588 |
| ST6GALNAC4 | 0.0312871 |
| TLX3 | 0.0312837 |
| TBATA | 0.0312625 |
| C2orf50 | 0.0312441 |
| SCT | 0.0311764 |
| AMOT | 0.0311706 |
| THYN1 | 0.0311672 |
| CNGB1 | 0.0311566 |
| ZNF184 | 0.0311221 |
| C3orf38 | 0.0310954 |
| UBA3 | 0.0310896 |
| C9orf142 | 0.0310758 |
| TBCEL | 0.0310332 |
| KCTD5 | 0.0310171 |
| ACTC1 | 0.0309832 |
| EIF2AK3 | 0.0309674 |
| RUSC1 | 0.0309402 |
| RAPSN | 0.0309331 |
| HCN4 | 0.0309172 |
| ZFP91 | 0.0309040 |
| TNC | 0.0308905 |
| NFX1 | 0.0308759 |
| GOLM1 | 0.0308274 |
| BARD1 | 0.0307836 |
| UBE2V1 | 0.0307033 |
| WDR43 | 0.0306915 |
| TSPAN11 | 0.0306846 |
| RNF115 | 0.0306620 |
| IL21 | 0.0305766 |
| RNPEPL1 | 0.0305610 |
| RGR | 0.0305543 |
| DDX19B | 0.0305523 |
| DAB2 | 0.0305467 |
| RNF213 | 0.0305257 |
| CXCL3 | 0.0305139 |
| TSPAN17 | 0.0305094 |
| NPR3 | 0.0304975 |
| MT1F | 0.0304699 |
| SLC6A6 | 0.0304643 |
| PRDX5 | 0.0303310 |
| TMEM217 | 0.0303032 |
| LSG1 | 0.0303006 |
| TLN1 | 0.0302937 |
| ABCD1 | 0.0302564 |
| BPNT1 | 0.0302468 |
| STAMBP | 0.0301966 |
| SLC27A6 | 0.0301823 |
| SURF2 | 0.0301543 |
| MRPL18 | 0.0301364 |
| SLC1A6 | 0.0300534 |
| LSM10 | 0.0300503 |
| TDG | 0.0300303 |
| ATAD2B | 0.0300228 |
| GIT1 | 0.0300098 |
| POLD3 | 0.0300087 |
| SIPA1L1 | 0.0299940 |
| FOXRED2 | 0.0299665 |
| CHMP7 | 0.0299630 |
| DTX3L | 0.0299349 |
| MXRA5 | 0.0299208 |
| PSMD10 | 0.0299057 |
| PNO1 | 0.0298942 |
| PPP1CC | 0.0298444 |
| SZRD1 | 0.0298337 |
| ARSJ | 0.0298244 |
| AP5M1 | 0.0298090 |
| MTAP | 0.0298086 |
| SAE1 | 0.0297016 |
| CTXN1 | 0.0296971 |
| ADAD1 | 0.0296876 |
| NADK | 0.0296612 |
| UBE2NL | 0.0296597 |
| CCL25 | 0.0296491 |
| DRAP1 | 0.0296092 |
| GK5 | 0.0295779 |
| AQP3 | 0.0295331 |
| GRAMD1B | 0.0295226 |
| MGLL | 0.0295192 |
| FOXF1 | 0.0294814 |
| SHISA7 | 0.0294703 |
| DIABLO | 0.0294401 |
| KLF16 | 0.0293828 |
| CSF1 | 0.0293718 |
| KBTBD12 | 0.0293287 |
| TIMM44 | 0.0293197 |
| PI4K2A | 0.0292802 |
| ZNF567 | 0.0292772 |
| NFKBID | 0.0292223 |
| LSS | 0.0291912 |
| GNAI2 | 0.0291775 |
| HIGD2A | 0.0291478 |
| CRHR1 | 0.0291073 |
| TRIB3 | 0.0290370 |
| TEAD2 | 0.0288865 |
| ERMP1 | 0.0288838 |
| SEC23B | 0.0288721 |
| PGPEP1L | 0.0288688 |
| YIPF1 | 0.0288542 |
| SDK2 | 0.0288347 |
| CHD4 | 0.0287695 |
| HAS3 | 0.0287640 |
| KIF17 | 0.0286887 |
| NOS3 | 0.0286702 |
| EEF1B2 | 0.0286686 |
| PPP1R13L | 0.0286382 |
| XRN2 | 0.0286278 |
| CNTNAP3 | 0.0286273 |
| C17orf50 | 0.0286216 |
| GRIK5 | 0.0285942 |
| LOX | 0.0285694 |
| CYP11A1 | 0.0285681 |
| MOB2 | 0.0285593 |
| KRT80 | 0.0285467 |
| MED30 | 0.0285433 |
| RETN | 0.0285316 |
| PPP4C | 0.0285299 |
| SLC51A | 0.0285274 |
| PINX1 | 0.0285152 |
| KIAA2013 | 0.0285048 |
| PTGIS | 0.0284959 |
| CASC10 | 0.0284841 |
| RXFP3 | 0.0284710 |
| IKBKE | 0.0284672 |
| SIRT6 | 0.0284638 |
| RELA | 0.0284585 |
| RPS27A | 0.0284533 |
| TRAPPC10 | 0.0284460 |
| CYLD | 0.0284371 |
| NRROS | 0.0284035 |
| ZNF131 | 0.0283995 |
| MEFV | 0.0283522 |
| SYT11 | 0.0283277 |
| NKRF | 0.0283226 |
| CNTRL | 0.0283220 |
| KPTN | 0.0283168 |
| EIF4G2 | 0.0283130 |
| AIDA | 0.0282567 |
| EID2 | 0.0282464 |
| DHFR | 0.0282167 |
| WDR77 | 0.0281828 |
| ACE | 0.0281266 |
| NSMAF | 0.0281030 |
| DUSP11 | 0.0280823 |
| PSMD1 | 0.0280416 |
| SH3GLB1 | 0.0280390 |
| GDF5 | 0.0279922 |
| ARL6IP6 | 0.0279807 |
| RNASEK | 0.0279725 |
| SLC6A20 | 0.0279621 |
| CECR2 | 0.0279423 |
| PIGA | 0.0279392 |
| HMGN1 | 0.0279288 |
| CNOT3 | 0.0278711 |
| RETNLB | 0.0278388 |
| NTAN1 | 0.0278334 |
| PARK2 | 0.0278257 |
| GXYLT1 | 0.0278125 |
| MRPL45 | 0.0277954 |
| TMEM2 | 0.0277850 |
| RPL21 | 0.0277714 |
| DUSP5 | 0.0277664 |
| C9orf62 | 0.0277504 |
| CDK19 | 0.0277497 |
| NOL10 | 0.0277135 |
| HIST3H3 | 0.0277132 |
| ALG5 | 0.0277126 |
| RASL11A | 0.0277087 |
| NOMO1 | 0.0276965 |
| ATP10B | 0.0276709 |
| CDC37 | 0.0276574 |
| PRRG1 | 0.0276480 |
| PBXIP1 | 0.0276094 |
| FUCA1 | 0.0275245 |
| ALOX12B | 0.0274977 |
| SCMH1 | 0.0274957 |
| SH3BP5 | 0.0274723 |
| DHRS11 | 0.0273705 |
| CCSER2 | 0.0273634 |
| SCARB2 | 0.0273413 |
| SLC25A17 | 0.0273346 |
| RNASE3 | 0.0273121 |
| HIST1H4D | 0.0272780 |
| PSD4 | 0.0272759 |
| IL18R1 | 0.0272590 |
| PLXNA1 | 0.0272533 |
| MED27 | 0.0272471 |
| EIF2B5 | 0.0272211 |
| CNTROB | 0.0272124 |
| LIX1L | 0.0271993 |
| IQSEC1 | 0.0271989 |
| VPS4A | 0.0271610 |
| NQO2 | 0.0271561 |
| GCAT | 0.0271472 |
| NES | 0.0270356 |
| TIMMDC1 | 0.0270288 |
| GBF1 | 0.0270214 |
| ABHD16A | 0.0270133 |
| PON2 | 0.0270126 |
| NDUFB9 | 0.0270029 |
| PCDHA5 | 0.0269916 |
| MAP2K2 | 0.0269893 |
| MRPL14 | 0.0269404 |
| PCNXL3 | 0.0269204 |
| DNAJC13 | 0.0269088 |
| SLCO2A1 | 0.0268755 |
| LRRC31 | 0.0268738 |
| WDFY2 | 0.0268729 |
| ZNF212 | 0.0268512 |
| SIRT5 | 0.0268034 |
| FOXE1 | 0.0267891 |
| ADRBK1 | 0.0267660 |
| FCRL1 | 0.0267544 |
| MED9 | 0.0267540 |
| KIAA0226L | 0.0267428 |
| PTGFR | 0.0266984 |
| PHC2 | 0.0266885 |
| TPGS2 | 0.0266735 |
| EIF2S3 | 0.0266719 |
| DDX49 | 0.0266177 |
| ZNF33A | 0.0265856 |
| SCARF1 | 0.0265820 |
| RPL39 | 0.0265755 |
| TMEM63B | 0.0265503 |
| SPINK1 | 0.0265488 |
| KIAA0101 | 0.0265382 |
| FAM53B | 0.0265011 |
| CPOX | 0.0264786 |
| ACP2 | 0.0264456 |
| ANGPTL4 | 0.0264325 |
| CYGB | 0.0263900 |
| OLFML2B | 0.0263838 |
| LGI3 | 0.0263763 |
| PRRC2A | 0.0263744 |
| TGFB1 | 0.0263293 |
| PDE4DIP | 0.0263048 |
| SPRY3 | 0.0262749 |
| FSCN3 | 0.0262654 |
| CTDP1 | 0.0262273 |
| TAF1A | 0.0262250 |
| SLC35A1 | 0.0262045 |
| FBXO30 | 0.0262029 |
| ARRDC2 | 0.0261840 |
| GSR | 0.0261678 |
| STRA6 | 0.0261574 |
| E2F7 | 0.0261559 |
| TMEM216 | 0.0261277 |
| TMEM41A | 0.0260980 |
| C12orf75 | 0.0260949 |
| LHFPL5 | 0.0260886 |
| DDX5 | 0.0260704 |
| GNG8 | 0.0260500 |
| GIT2 | 0.0260346 |
| TMEM201 | 0.0260297 |
| SMC3 | 0.0259470 |
| SLC50A1 | 0.0259078 |
| DCTN3 | 0.0259010 |
| TLR3 | 0.0258376 |
| ZNF207 | 0.0257768 |
| RING1 | 0.0257605 |
| TCHP | 0.0257492 |
| PKP2 | 0.0257424 |
| REPIN1 | 0.0256992 |
| TXNDC9 | 0.0256650 |
| INO80C | 0.0256525 |
| FAM179A | 0.0256131 |
| DNAJB5 | 0.0255972 |
| C11orf48 | 0.0255907 |
| LTBP1 | 0.0255894 |
| GNA13 | 0.0255513 |
| CSTF1 | 0.0255400 |
| SLC25A44 | 0.0255353 |
| PABPC4 | 0.0255099 |
| MOS | 0.0254561 |
| FAM109A | 0.0253226 |
| NSG1 | 0.0252586 |
| NME8 | 0.0252480 |
| FGD5 | 0.0252046 |
| NDUFB11 | 0.0251242 |
| VTI1A | 0.0251094 |
| MLXIP | 0.0250508 |
| ACHE | 0.0250324 |
| BFSP1 | 0.0249880 |
| RPIA | 0.0249774 |
| C15orf38 | 0.0249737 |
| NRP2 | 0.0248647 |
| UGT2A1 | 0.0248088 |
| CNPPD1 | 0.0247932 |
| FANCL | 0.0247699 |
| ZBTB21 | 0.0247271 |
| RDH12 | 0.0246703 |
| GPR15 | 0.0246606 |
| OR5F1 | 0.0246315 |
| SGPP1 | 0.0246294 |
| OPN4 | 0.0246243 |
| DHX9 | 0.0245661 |
| IL33 | 0.0245241 |
| LRP12 | 0.0245026 |
| MAPK14 | 0.0244961 |
| OPN1SW | 0.0244960 |
| WIPI1 | 0.0244737 |
| TOPBP1 | 0.0244569 |
| CPSF6 | 0.0244377 |
| UTP18 | 0.0244247 |
| ZP4 | 0.0243759 |
| LYRM2 | 0.0242811 |
| FKBP1A | 0.0242735 |
| ATM | 0.0242574 |
| BABAM1 | 0.0242229 |
| PSMD6 | 0.0242215 |
| MAPK1IP1L | 0.0241862 |
| HGS | 0.0241684 |
| RWDD2B | 0.0241480 |
| BRD9 | 0.0241458 |
| LFNG | 0.0240827 |
| MRPL48 | 0.0240180 |
| TMED5 | 0.0239968 |
| TFAP2E | 0.0239825 |
| TMEM38B | 0.0239289 |
| RUVBL1 | 0.0238420 |
| DDX18 | 0.0238410 |
| SEC16A | 0.0237860 |
| GPR64 | 0.0237855 |
| CLEC2D | 0.0237792 |
| RPS18 | 0.0237707 |
| TVP23C | 0.0237508 |
| TRMT11 | 0.0237477 |
| MOCS3 | 0.0237369 |
| HIC2 | 0.0237274 |
| RPL23A | 0.0237200 |
| LIN37 | 0.0237010 |
| SPRR2D | 0.0236683 |
| EFNA2 | 0.0236516 |
| MED6 | 0.0236282 |
| DDX31 | 0.0236176 |
| BTN2A1 | 0.0236163 |
| PCDHB13 | 0.0236052 |
| GCSAM | 0.0235751 |
| UBC | 0.0235692 |
| NCR2 | 0.0235495 |
| SLC36A1 | 0.0235324 |
| MEN1 | 0.0235173 |
| ATP6V0E1 | 0.0235143 |
| UBL4A | 0.0235018 |
| CDRT1 | 0.0234785 |
| HIST1H2BL | 0.0234711 |
| SMURF2 | 0.0234626 |
| SLC30A7 | 0.0234446 |
| KIF20B | 0.0234286 |
| ATP5O | 0.0234223 |
| WFDC3 | 0.0233652 |
| QPCTL | 0.0233535 |
| DDR2 | 0.0233498 |
| DGKG | 0.0233320 |
| CCDC28A | 0.0233293 |
| HNRNPH3 | 0.0233259 |
| YIPF3 | 0.0233245 |
| ARHGAP33 | 0.0233156 |
| FAM210B | 0.0233051 |
| CST2 | 0.0232975 |
| RCN3 | 0.0232901 |
| MED18 | 0.0232604 |
| ACTR5 | 0.0232403 |
| QKI | 0.0232269 |
| USP10 | 0.0232222 |
| POLR2C | 0.0231978 |
| EFNA5 | 0.0231975 |
| YPEL4 | 0.0231768 |
| MAP2K1 | 0.0231728 |
| FCGBP | 0.0231463 |
| TRMT6 | 0.0231426 |
| STAM | 0.0231247 |
| ATXN7L2 | 0.0231229 |
| WDR12 | 0.0230907 |
| ACRBP | 0.0230174 |
| ST6GALNAC1 | 0.0229748 |
| GPR158 | 0.0229497 |
| RAD51 | 0.0229406 |
| SLC25A15 | 0.0229231 |
| XPO4 | 0.0229096 |
| MED11 | 0.0229021 |
| TIPIN | 0.0228663 |
| CR1L | 0.0228645 |
| CNFN | 0.0228517 |
| PTS | 0.0228314 |
| TET1 | 0.0228285 |
| CARHSP1 | 0.0227571 |
| RAB24 | 0.0227352 |
| BPHL | 0.0227311 |
| CMTR1 | 0.0227125 |
| DGCR8 | 0.0227047 |
| SS18L2 | 0.0226280 |
| PLA2G2D | 0.0226245 |
| NLE1 | 0.0225941 |
| EXOC3L2 | 0.0225266 |
| ETHE1 | 0.0225205 |
| ATP8B4 | 0.0225069 |
| MUS81 | 0.0224922 |
| IDE | 0.0224756 |
| RPL7A | 0.0224729 |
| C6orf47 | 0.0224510 |
| CCDC179 | 0.0223768 |
| NDUFB8 | 0.0223542 |
| OR10A5 | 0.0223476 |
| RFC5 | 0.0223236 |
| ESX1 | 0.0223094 |
| SAMD9 | 0.0223078 |
| CDK16 | 0.0222583 |
| ATP6V1E1 | 0.0222536 |
| PC | 0.0222156 |
| ATP8A2 | 0.0222013 |
| LATS2 | 0.0221993 |
| MCTP1 | 0.0221992 |
| FAM153A | 0.0221901 |
| FDFT1 | 0.0221633 |
| OSBPL11 | 0.0221364 |
| DPF3 | 0.0221296 |
| FCHSD2 | 0.0221104 |
| CHST13 | 0.0220796 |
| FCAMR | 0.0220755 |
| SCAF4 | 0.0220343 |
| FAM115C | 0.0220157 |
| SLC1A7 | 0.0219927 |
| PLOD2 | 0.0219773 |
| ITGB1 | 0.0219637 |
| COL13A1 | 0.0219600 |
| CXCL6 | 0.0219590 |
| PLA2G4C | 0.0219478 |
| NCLN | 0.0219475 |
| HSPB11 | 0.0219439 |
| USF1 | 0.0219139 |
| GPR68 | 0.0219107 |
| FUT11 | 0.0218964 |
| WBP5 | 0.0218862 |
| SLC5A2 | 0.0218836 |
| CCDC14 | 0.0218579 |
| PTPN3 | 0.0218417 |
| MSI1 | 0.0218324 |
| RNF166 | 0.0218064 |
| MGAT2 | 0.0217810 |
| RNF138 | 0.0217807 |
| TXNL4B | 0.0217799 |
| ENG | 0.0217674 |
| TRIM39 | 0.0217658 |
| USP20 | 0.0217423 |
| ABHD15 | 0.0217404 |
| KAT2B | 0.0217318 |
| APCDD1L | 0.0217266 |
| DAD1 | 0.0216911 |
| OR5L2 | 0.0216710 |
| TIFA | 0.0216587 |
| HABP4 | 0.0216537 |
| THOC5 | 0.0216464 |
| FAM92A1 | 0.0216365 |
| TMEM234 | 0.0216273 |
| CACTIN | 0.0215779 |
| SMNDC1 | 0.0215747 |
| SIM1 | 0.0215632 |
| SCAMP2 | 0.0215171 |
| FAM53C | 0.0215030 |
| USPL1 | 0.0214735 |
| ANK3 | 0.0214505 |
| COL4A3 | 0.0214487 |
| CCL26 | 0.0214398 |
| GRAMD4 | 0.0214206 |
| GPS2 | 0.0213913 |
| STAB2 | 0.0213822 |
| RFXANK | 0.0213742 |
| GALT | 0.0213539 |
| PTBP1 | 0.0213498 |
| PDAP1 | 0.0212938 |
| TRAF3IP2 | 0.0212838 |
| SIRT2 | 0.0212786 |
| FNIP2 | 0.0212661 |
| NSUN3 | 0.0212621 |
| PPL | 0.0212617 |
| CBLB | 0.0212551 |
| AKAP13 | 0.0212437 |
| IVNS1ABP | 0.0212364 |
| CCDC88A | 0.0212292 |
| EFTUD2 | 0.0212187 |
| MAST3 | 0.0211914 |
| C4orf46 | 0.0211696 |
| GALNT2 | 0.0211654 |
| IFITM1 | 0.0211401 |
| H1FNT | 0.0211343 |
| ID3 | 0.0211179 |
| FAM126A | 0.0211144 |
| C4orf27 | 0.0210950 |
| NDUFAF5 | 0.0210747 |
| KIF5B | 0.0210385 |
| SH3BP2 | 0.0210313 |
| RHOQ | 0.0210161 |
| ASB10 | 0.0210158 |
| KIR2DL4 | 0.0210098 |
| SLC6A18 | 0.0209769 |
| MAN2A1 | 0.0209458 |
| BIRC2 | 0.0209373 |
| KLF14 | 0.0209271 |
| RDH11 | 0.0208959 |
| TSPAN2 | 0.0208819 |
| PRKCA | 0.0208679 |
| C1orf61 | 0.0208631 |
| MIPEP | 0.0208607 |
| SH2D5 | 0.0208583 |
| DDX60 | 0.0208472 |
| NOS2 | 0.0208449 |
| ILF3 | 0.0207828 |
| PPP4R1 | 0.0207737 |
| TDRD7 | 0.0207639 |
| ISG20L2 | 0.0207599 |
| P2RX1 | 0.0207449 |
| ADAMTSL4 | 0.0207301 |
| ALKBH4 | 0.0207046 |
| GPR108 | 0.0207002 |
| PTP4A1 | 0.0206911 |
| ETS2 | 0.0206679 |
| TACR2 | 0.0206600 |
| TRIP6 | 0.0206495 |
| LSM12 | 0.0206467 |
| HSP90AA1 | 0.0206154 |
| NLRX1 | 0.0205972 |
| DPP3 | 0.0205918 |
| PLEKHJ1 | 0.0205849 |
| AMPD2 | 0.0205829 |
| TRANK1 | 0.0205545 |
| SAR1A | 0.0205247 |
| DDX19A | 0.0205227 |
| PMM2 | 0.0205078 |
| TCOF1 | 0.0204886 |
| NR2C2AP | 0.0204668 |
| CYCS | 0.0204109 |
| ZBTB33 | 0.0204099 |
| BUD31 | 0.0203980 |
| CWC22 | 0.0203469 |
| FBXW2 | 0.0203439 |
| NIPA2 | 0.0203199 |
| DBR1 | 0.0203118 |
| ATG13 | 0.0203089 |
| TIMP1 | 0.0202989 |
| PLBD2 | 0.0202336 |
| KLF6 | 0.0202285 |
| KRTAP2-4 | 0.0202022 |
| PCID2 | 0.0201992 |
| POLR3C | 0.0201946 |
| CABIN1 | 0.0201881 |
| SRMS | 0.0201664 |
| SEMA5B | 0.0201625 |
| ASAP1 | 0.0201557 |
| CDKL1 | 0.0201512 |
| PDCD2 | 0.0201141 |
| MXD3 | 0.0200669 |
| ZC3HAV1L | 0.0200636 |
| UBR2 | 0.0200578 |
| UNG | 0.0200447 |
| GCFC2 | 0.0200435 |
| CHRNE | 0.0200385 |
| TMED3 | 0.0200116 |
| PNPT1 | 0.0199989 |
| USP24 | 0.0199919 |
| DCAF4 | 0.0199910 |
| KLHDC4 | 0.0199429 |
| METAP1 | 0.0199405 |
| TMX4 | 0.0198972 |
| CD3EAP | 0.0198818 |
| GTF3C2 | 0.0198538 |
| SH2B3 | 0.0198339 |
| TUBB2B | 0.0198337 |
| MTSS1L | 0.0198311 |
| PTPRS | 0.0197886 |
| UBB | 0.0197759 |
| IWS1 | 0.0197757 |
| HSPD1 | 0.0197555 |
| PMM1 | 0.0197554 |
| SBK2 | 0.0197460 |
| ANKRD44 | 0.0196878 |
| PSAPL1 | 0.0196711 |
| PACSIN3 | 0.0196470 |
| CSRP1 | 0.0195731 |
| PRPSAP2 | 0.0195569 |
| SEC22A | 0.0195530 |
| CSTF3 | 0.0195362 |
| HEG1 | 0.0195007 |
| ACSL6 | 0.0194770 |
| C9orf139 | 0.0194539 |
| POM121L12 | 0.0194524 |
| OST4 | 0.0194430 |
| SPTLC3 | 0.0194102 |
| MTOR | 0.0193561 |
| KCNK17 | 0.0193368 |
| GSKIP | 0.0193169 |
| TBC1D23 | 0.0192909 |
| RAB3GAP1 | 0.0192612 |
| HRG | 0.0192477 |
| ACER3 | 0.0192268 |
| SCGB3A2 | 0.0192174 |
| CKM | 0.0192110 |
| NTSR1 | 0.0191897 |
| NDUFB5 | 0.0191817 |
| COA6 | 0.0191703 |
| FAM167B | 0.0191529 |
| FOXP3 | 0.0191356 |
| CACUL1 | 0.0191199 |
| MAFG | 0.0191146 |
| R3HDML | 0.0190846 |
| MDH2 | 0.0190738 |
| FRMD4B | 0.0190444 |
| EIF4H | 0.0190427 |
| C4BPA | 0.0190297 |
| TLX2 | 0.0190006 |
| PAPOLA | 0.0189891 |
| TBC1D5 | 0.0189518 |
| ZNF598 | 0.0189510 |
| KRTAP11-1 | 0.0189315 |
| C11orf80 | 0.0189243 |
| STOM | 0.0189101 |
| PIM3 | 0.0188977 |
| ABHD17B | 0.0188953 |
| ODF3L2 | 0.0188917 |
| COMMD3 | 0.0188848 |
| LILRA5 | 0.0188774 |
| FBXL6 | 0.0188552 |
| TM4SF4 | 0.0188372 |
| GABPB1 | 0.0188302 |
| ERN2 | 0.0188290 |
| ATMIN | 0.0188281 |
| APOBEC3D | 0.0188134 |
| TRABD2B | 0.0188058 |
| NOP10 | 0.0187792 |
| JDP2 | 0.0187645 |
| WDR82 | 0.0187150 |
| RNF167 | 0.0187139 |
| ANKRD35 | 0.0186862 |
| RPL10L | 0.0186845 |
| B3GNT2 | 0.0186670 |
| OR4C15 | 0.0186566 |
| HSD17B12 | 0.0186432 |
| SMEK2 | 0.0186183 |
| KLC1 | 0.0185195 |
| MMP28 | 0.0184968 |
| SUMO2 | 0.0184936 |
| RAB36 | 0.0184697 |
| SLC22A10 | 0.0184643 |
| MRTO4 | 0.0184524 |
| VASH1 | 0.0184260 |
| SNRNP200 | 0.0184149 |
| GPA33 | 0.0183276 |
| RAB8A | 0.0183102 |
| PLCD1 | 0.0183062 |
| SERPINB7 | 0.0182515 |
| LMBRD1 | 0.0182380 |
| GCM1 | 0.0181721 |
| MTRR | 0.0181649 |
| HPS1 | 0.0181447 |
| IFT27 | 0.0181264 |
| PDE4C | 0.0181075 |
| ASB6 | 0.0181060 |
| SLC39A9 | 0.0181049 |
| C5orf34 | 0.0180965 |
| CLPTM1 | 0.0180905 |
| KLF4 | 0.0180851 |
| DGUOK | 0.0180794 |
| GSDMA | 0.0180499 |
| FDX1 | 0.0180322 |
| KIAA0586 | 0.0179833 |
| MYO19 | 0.0179434 |
| HDX | 0.0179333 |
| IGFBPL1 | 0.0179036 |
| NUP37 | 0.0178773 |
| C22orf29 | 0.0178751 |
| CYP2D6 | 0.0178586 |
| SEL1L | 0.0178450 |
| GMPR | 0.0178277 |
| TMEM114 | 0.0178203 |
| PCDHGA7 | 0.0177984 |
| LSAMP | 0.0177968 |
| AP3D1 | 0.0177705 |
| PPM1M | 0.0177532 |
| PPP1R7 | 0.0177096 |
| HIP1R | 0.0177086 |
| ZNF713 | 0.0177072 |
| FAM192A | 0.0176999 |
| TRMT61A | 0.0176854 |
| DAP3 | 0.0176830 |
| OGT | 0.0176781 |
| LRRC37A2 | 0.0176316 |
| WFDC9 | 0.0176145 |
| MARCH7 | 0.0176122 |
| VTA1 | 0.0176032 |
| EPHA4 | 0.0175999 |
| ANKRD49 | 0.0175907 |
| STAR | 0.0175752 |
| NAA35 | 0.0175716 |
| POLR2B | 0.0175668 |
| GCNT3 | 0.0175566 |
| EXO5 | 0.0175040 |
| TMEM72 | 0.0174856 |
| FTSJ3 | 0.0174667 |
| GFI1B | 0.0174496 |
| LINC00998 | 0.0174385 |
| C9orf163 | 0.0174188 |
| XKRX | 0.0173771 |
| MARK3 | 0.0173560 |
| DCAF12 | 0.0173065 |
| CDC42 | 0.0172759 |
| C3orf58 | 0.0172608 |
| LONRF3 | 0.0172570 |
| MSL2 | 0.0172512 |
| XPC | 0.0172485 |
| WDR37 | 0.0172122 |
| CCDC12 | 0.0172083 |
| CUL9 | 0.0171709 |
| FAM159A | 0.0171665 |
| COL9A2 | 0.0171275 |
| MMP14 | 0.0171174 |
| ATXN7L1 | 0.0171146 |
| MMP2 | 0.0171134 |
| BLMH | 0.0170823 |
| NUDT7 | 0.0170791 |
| CDH24 | 0.0170289 |
| CCZ1B | 0.0169862 |
| TMED9 | 0.0169833 |
| TRMT10C | 0.0169823 |
| CEP85L | 0.0169692 |
| COX7B2 | 0.0169268 |
| CCR10 | 0.0169243 |
| ERRFI1 | 0.0169176 |
| TXLNB | 0.0169166 |
| PCOLCE | 0.0168906 |
| SEC23A | 0.0168737 |
| RASGRP4 | 0.0168642 |
| LAMB3 | 0.0168371 |
| ZNF276 | 0.0168290 |
| FBXO10 | 0.0168171 |
| TDRD12 | 0.0167649 |
| MEF2D | 0.0167634 |
| RPSA | 0.0167601 |
| OR51G1 | 0.0167320 |
| RARS2 | 0.0167272 |
| HHIPL1 | 0.0167104 |
| STX6 | 0.0167061 |
| TAF13 | 0.0166993 |
| TLX1 | 0.0166919 |
| LYG1 | 0.0166712 |
| IFT172 | 0.0166342 |
| SRRM1 | 0.0166283 |
| MAB21L3 | 0.0166226 |
| MFF | 0.0166040 |
| CDKN1C | 0.0165915 |
| NLN | 0.0165768 |
| TMEM154 | 0.0165674 |
| CREB3 | 0.0165520 |
| KIAA1210 | 0.0165467 |
| NBEAL2 | 0.0165347 |
| FGFBP3 | 0.0165233 |
| TESK1 | 0.0165084 |
| RPL3L | 0.0164729 |
| KLF12 | 0.0164676 |
| LSM3 | 0.0164656 |
| FAM118A | 0.0164549 |
| HLX | 0.0164268 |
| KRT34 | 0.0164201 |
| FERMT2 | 0.0164195 |
| SLC17A3 | 0.0164017 |
| CEP192 | 0.0163476 |
| POLA1 | 0.0163323 |
| TOR1A | 0.0163191 |
| PIGC | 0.0163097 |
| MED26 | 0.0163072 |
| ARSI | 0.0162828 |
| PXDN | 0.0162790 |
| DNM3 | 0.0162491 |
| TNP2 | 0.0162225 |
| LARP4B | 0.0162099 |
| FAM195B | 0.0161950 |
| UBE3C | 0.0161904 |
| METTL4 | 0.0161779 |
| NUDT22 | 0.0161724 |
| EVA1C | 0.0161663 |
| TGFA | 0.0161415 |
| TAB2 | 0.0161409 |
| PWP1 | 0.0161014 |
| OR10A2 | 0.0160893 |
| STAG1 | 0.0160841 |
| RNF5 | 0.0160807 |
| C14orf2 | 0.0160738 |
| LACRT | 0.0160466 |
| HESX1 | 0.0160390 |
| LOXL3 | 0.0160293 |
| ULBP1 | 0.0160165 |
| SLC14A2 | 0.0159745 |
| VTI1B | 0.0159450 |
| KIF1C | 0.0159186 |
| CACNA1B | 0.0159157 |
| RPL4 | 0.0158768 |
| CNPY3 | 0.0158520 |
| CWF19L1 | 0.0158427 |
| ATP10A | 0.0157986 |
| ZBED1 | 0.0157765 |
| FAM213A | 0.0157555 |
| SERPINB3 | 0.0157511 |
| ETV5 | 0.0157138 |
| HACE1 | 0.0157119 |
| TBC1D31 | 0.0157031 |
| MSANTD4 | 0.0156769 |
| RWDD1 | 0.0156383 |
| C10orf2 | 0.0156358 |
| YOD1 | 0.0156357 |
| SRP72 | 0.0156186 |
| KATNB1 | 0.0156063 |
| P2RY13 | 0.0155974 |
| DAB2IP | 0.0155946 |
| KLHL33 | 0.0155889 |
| ROCK2 | 0.0155758 |
| MPRIP | 0.0155483 |
| TG | 0.0155268 |
| DLAT | 0.0155187 |
| SPRY1 | 0.0154994 |
| MR1 | 0.0154557 |
| PXDNL | 0.0154522 |
| TNRC18 | 0.0154399 |
| SLC29A2 | 0.0154287 |
| LTBP4 | 0.0154159 |
| BOLA1 | 0.0153988 |
| ABT1 | 0.0153890 |
| NYNRIN | 0.0153763 |
| NPAT | 0.0153448 |
| BCL9L | 0.0153326 |
| XPO6 | 0.0153135 |
| TTC4 | 0.0153050 |
| CCR8 | 0.0153005 |
| RNF13 | 0.0152679 |
| KIF25 | 0.0152665 |
| PLCXD2 | 0.0152659 |
| ZNF777 | 0.0152483 |
| RBMX2 | 0.0152443 |
| C18orf21 | 0.0152375 |
| LIF | 0.0152258 |
| IKBIP | 0.0152117 |
| NUP54 | 0.0151900 |
| ADAMTS5 | 0.0151877 |
| GCA | 0.0151532 |
| CELA2B | 0.0151439 |
| MAN1B1 | 0.0151261 |
| FBXL13 | 0.0151016 |
| TPM3 | 0.0150793 |
| MB21D2 | 0.0150759 |
| TMEM151A | 0.0150427 |
| BRMS1 | 0.0150277 |
| COX6B2 | 0.0150145 |
| TCF25 | 0.0150141 |
| OR2B6 | 0.0149768 |
| COL9A1 | 0.0149598 |
| ANKZF1 | 0.0149071 |
| HCRT | 0.0148938 |
| TEX261 | 0.0148851 |
| ABCC12 | 0.0148814 |
| PI4KA | 0.0148761 |
| PRR21 | 0.0148747 |
| SUCNR1 | 0.0148739 |
| FXN | 0.0148162 |
| C22orf46 | 0.0148044 |
| STARD8 | 0.0147955 |
| MRPL40 | 0.0147677 |
| LPCAT2 | 0.0147494 |
| TAF4B | 0.0147485 |
| RGS2 | 0.0147400 |
| CLCN1 | 0.0147108 |
| PRIMA1 | 0.0146948 |
| C1orf105 | 0.0146685 |
| CLDN16 | 0.0146522 |
| DAAM2 | 0.0146511 |
| SAMD10 | 0.0146163 |
| LMO7 | 0.0146146 |
| FAM188B | 0.0145721 |
| ZNRD1 | 0.0145678 |
| C10orf128 | 0.0145415 |
| FAIM | 0.0145353 |
| XPOT | 0.0145049 |
| PSENEN | 0.0144979 |
| ZMYM3 | 0.0144654 |
| FAM117A | 0.0143760 |
| MIOX | 0.0142964 |
| LBX1 | 0.0142960 |
| C8orf56 | 0.0142875 |
| CDKL5 | 0.0142846 |
| ATF6B | 0.0142785 |
| MRPS2 | 0.0142754 |
| SMG8 | 0.0142748 |
| ZNF519 | 0.0142712 |
| LMF2 | 0.0142677 |
| TRMT5 | 0.0142359 |
| KCTD19 | 0.0142204 |
| WDYHV1 | 0.0142115 |
| KIAA1671 | 0.0141939 |
| MTMR8 | 0.0141780 |
| PARP4 | 0.0141698 |
| ODF2 | 0.0141369 |
| PTBP3 | 0.0141203 |
| RNF126 | 0.0141110 |
| EMD | 0.0140901 |
| EME1 | 0.0140736 |
| BOLA3 | 0.0140638 |
| AAMP | 0.0140586 |
| TOB2 | 0.0140443 |
| TMEM14A | 0.0140199 |
| RASSF1 | 0.0139876 |
| FBXO9 | 0.0139793 |
| MINK1 | 0.0139765 |
| RAD51B | 0.0139692 |
| APOA2 | 0.0139497 |
| ANTXR2 | 0.0139401 |
| ATP5J | 0.0139261 |
| CCDC150 | 0.0139109 |
| HMOX1 | 0.0138979 |
| SERHL2 | 0.0138958 |
| C6orf132 | 0.0138765 |
| TTC1 | 0.0138612 |
| TSC22D2 | 0.0138156 |
| SPRY4 | 0.0137951 |
| INVS | 0.0137754 |
| SRBD1 | 0.0137600 |
| ATP5B | 0.0137526 |
| HBS1L | 0.0136799 |
| SLC16A13 | 0.0136791 |
| PTP4A3 | 0.0136534 |
| TMEM208 | 0.0136466 |
| PCBP3 | 0.0136352 |
| SH3BP5L | 0.0135930 |
| OPA3 | 0.0135731 |
| ETV3 | 0.0134964 |
| DCAF13 | 0.0134925 |
| TMEM199 | 0.0134889 |
| PRKDC | 0.0134658 |
| SPAG7 | 0.0134420 |
| INHBE | 0.0134255 |
| DGKH | 0.0133919 |
| MLF1 | 0.0133854 |
| YTHDF2 | 0.0133595 |
| NXNL1 | 0.0133594 |
| ISCA2 | 0.0133513 |
| KIAA2022 | 0.0133295 |
| CETP | 0.0133226 |
| C21orf119 | 0.0133202 |
| TRABD | 0.0133001 |
| HOXA4 | 0.0132970 |
| MAGEC2 | 0.0132487 |
| RNF165 | 0.0132376 |
| MFN1 | 0.0132267 |
| ZKSCAN4 | 0.0132080 |
| TBCB | 0.0132064 |
| KIAA1841 | 0.0132006 |
| SNRNP27 | 0.0131855 |
| CAGE1 | 0.0131645 |
| MBIP | 0.0131545 |
| LCLAT1 | 0.0131242 |
| KDM5C | 0.0131191 |
| MTERFD1 | 0.0131097 |
| ENTPD1 | 0.0130425 |
| NSUN5 | 0.0130379 |
| KDM1B | 0.0130325 |
| ESPL1 | 0.0129786 |
| SDF4 | 0.0129594 |
| CREM | 0.0128791 |
| PPIL2 | 0.0128492 |
| DDX39B | 0.0128465 |
| RC3H2 | 0.0128274 |
| SDCBP2 | 0.0128256 |
| NAT10 | 0.0128242 |
| SLBP | 0.0128072 |
| MVK | 0.0127929 |
| NFATC2 | 0.0127603 |
| TOP2B | 0.0127548 |
| MCFD2 | 0.0127476 |
| JTB | 0.0127104 |
| ORC5 | 0.0126818 |
| NEGR1 | 0.0126641 |
| CDX1 | 0.0126582 |
| UBA1 | 0.0126527 |
| VEGFC | 0.0125592 |
| KDM1A | 0.0125322 |
| B3GNT9 | 0.0125033 |
| MED22 | 0.0124869 |
| EIF3E | 0.0124644 |
| CUL4A | 0.0124538 |
| MRGPRF | 0.0124468 |
| RWDD2A | 0.0124338 |
| MROH7 | 0.0124102 |
| SNX18 | 0.0124046 |
| PICALM | 0.0124013 |
| RTN3 | 0.0123935 |
| SERPINB4 | 0.0123161 |
| CIB4 | 0.0122980 |
| GBP3 | 0.0122925 |
| PUSL1 | 0.0122646 |
| WDR70 | 0.0122563 |
| RBM23 | 0.0122502 |
| OR4D2 | 0.0122455 |
| NOL6 | 0.0122258 |
| ATF6 | 0.0122235 |
| FKRP | 0.0122111 |
| NCL | 0.0121778 |
| TRAFD1 | 0.0121559 |
| DHDH | 0.0121363 |
| VDAC3 | 0.0121307 |
| PSMD4 | 0.0121268 |
| AP1S2 | 0.0121251 |
| SCGB2A2 | 0.0121168 |
| NRSN2 | 0.0121165 |
| MAK16 | 0.0121019 |
| CTRL | 0.0120968 |
| SRSF4 | 0.0120903 |
| ELL2 | 0.0120870 |
| B3GNTL1 | 0.0120845 |
| TRIP12 | 0.0120740 |
| SUV39H1 | 0.0120209 |
| FAM219A | 0.0120131 |
| ZNF292 | 0.0120087 |
| MKRN3 | 0.0119785 |
| SORBS2 | 0.0119614 |
| DPP4 | 0.0119554 |
| KCNT1 | 0.0119338 |
| C10orf25 | 0.0118851 |
| PIK3R3 | 0.0118565 |
| DOT1L | 0.0118210 |
| MAGEB2 | 0.0117839 |
| SGMS1 | 0.0117569 |
| TANGO2 | 0.0117367 |
| NFYA | 0.0117316 |
| TAAR2 | 0.0117123 |
| PDK3 | 0.0116808 |
| AGBL3 | 0.0116363 |
| ABHD3 | 0.0116293 |
| DDB1 | 0.0115876 |
| THAP8 | 0.0115708 |
| MSI2 | 0.0115502 |
| C6orf99 | 0.0115457 |
| ARPC3 | 0.0115250 |
| SLCO4C1 | 0.0114271 |
| GOLT1B | 0.0114039 |
| OR4A15 | 0.0113835 |
| SIGLEC12 | 0.0113183 |
| TMEM159 | 0.0113008 |
| GALNT1 | 0.0112547 |
| KLK4 | 0.0112385 |
| SMAP1 | 0.0112206 |
| CBY1 | 0.0112199 |
| SRSF7 | 0.0112165 |
| OR6N1 | 0.0112072 |
| LGSN | 0.0111762 |
| ADRA1D | 0.0111377 |
| FAIM3 | 0.0111266 |
| MON1A | 0.0110964 |
| ID1 | 0.0110790 |
| TIMM22 | 0.0110586 |
| YWHAE | 0.0110433 |
| TRIM54 | 0.0110110 |
| RNFT2 | 0.0110102 |
| QRFPR | 0.0110033 |
| ARHGEF15 | 0.0109939 |
| FAM185A | 0.0109867 |
| GTF3C4 | 0.0109697 |
| CA6 | 0.0109299 |
| TMEM203 | 0.0109167 |
| EIF1AD | 0.0108546 |
| ALDH3B1 | 0.0108361 |
| ASXL1 | 0.0108172 |
| LMBR1L | 0.0108164 |
| NGDN | 0.0108163 |
| SF3A1 | 0.0108043 |
| CDIP1 | 0.0107730 |
| GAS2L1 | 0.0107558 |
| ZNF821 | 0.0107073 |
| PZP | 0.0106936 |
| FCRL3 | 0.0106879 |
| IPO13 | 0.0106745 |
| SBNO2 | 0.0106693 |
| HS6ST2 | 0.0106683 |
| NPLOC4 | 0.0106359 |
| CRNN | 0.0106258 |
| FAM124A | 0.0106200 |
| SPTA1 | 0.0106191 |
| FAM96A | 0.0106049 |
| ICAM5 | 0.0105867 |
| PSPC1 | 0.0105618 |
| TIMM8B | 0.0105223 |
| PLA1A | 0.0105186 |
| OR2H1 | 0.0105177 |
| SWAP70 | 0.0105127 |
| ZNF704 | 0.0104992 |
| COA1 | 0.0104856 |
| TRAPPC12 | 0.0104682 |
| COQ2 | 0.0104489 |
| NDUFS5 | 0.0104337 |
| BRINP3 | 0.0103575 |
| NDUFA8 | 0.0103458 |
| DPF2 | 0.0103443 |
| MRPS7 | 0.0103096 |
| DCUN1D1 | 0.0102641 |
| CRYAB | 0.0102582 |
| FBXL12 | 0.0102579 |
| HIST2H2AC | 0.0102357 |
| FUBP1 | 0.0102035 |
| MAP4K2 | 0.0101922 |
| IFNLR1 | 0.0101787 |
| GIPC1 | 0.0101725 |
| GPX8 | 0.0101719 |
| TOE1 | 0.0101610 |
| CALD1 | 0.0101547 |
| CANX | 0.0101388 |
| GALR2 | 0.0101336 |
| HMGN4 | 0.0101056 |
| ERCC5 | 0.0100993 |
| KDELC1 | 0.0100901 |
| GPR50 | 0.0100707 |
| SUGT1 | 0.0100554 |
| CCDC59 | 0.0100180 |
| RABL6 | 0.0100131 |
| ATP13A1 | 0.0100036 |
| MAX | 0.0099798 |
| LRRC3 | 0.0099726 |
| SFPQ | 0.0099695 |
| OR7A17 | 0.0099400 |
| FAM188A | 0.0099276 |
| ERC2 | 0.0099246 |
| CDR2 | 0.0099181 |
| NDUFV1 | 0.0098947 |
| NACC1 | 0.0098035 |
| MYOD1 | 0.0097909 |
| PIGS | 0.0097813 |
| TRIM35 | 0.0097800 |
| FAM151A | 0.0097778 |
| MBLAC1 | 0.0097261 |
| TAS2R60 | 0.0097247 |
| TMEM92 | 0.0096490 |
| CCDC177 | 0.0096474 |
| ZSCAN5A | 0.0096428 |
| CSH1 | 0.0096392 |
| IFNAR1 | 0.0096354 |
| INF2 | 0.0096182 |
| SLC35A2 | 0.0096150 |
| CSNK1E | 0.0096045 |
| TAF1B | 0.0095981 |
| PPP3CC | 0.0095972 |
| RNF44 | 0.0095919 |
| ZNF74 | 0.0095349 |
| GUCD1 | 0.0095270 |
| BNIP1 | 0.0095048 |
| NDUFA11 | 0.0094698 |
| FAM50B | 0.0094457 |
| BRD3 | 0.0094153 |
| DDX24 | 0.0093745 |
| PRRG3 | 0.0093547 |
| CBX3 | 0.0093059 |
| TRIM5 | 0.0093043 |
| APBA2 | 0.0092634 |
| OVCA2 | 0.0092506 |
| AKAP8 | 0.0092443 |
| CHTOP | 0.0092125 |
| RPL7 | 0.0092010 |
| HIST1H3A | 0.0091917 |
| UBE2G2 | 0.0091908 |
| FSTL1 | 0.0091882 |
| S100PBP | 0.0091845 |
| KHDRBS1 | 0.0091761 |
| MRPL38 | 0.0090979 |
| MKLN1 | 0.0090758 |
| KDELR1 | 0.0090506 |
| B4GALNT2 | 0.0090464 |
| ANKRD33B | 0.0090315 |
| METTL17 | 0.0090130 |
| TCEAL2 | 0.0089843 |
| MTDH | 0.0089678 |
| TMEM89 | 0.0089479 |
| OR8J1 | 0.0089238 |
| DMRT1 | 0.0089237 |
| RINT1 | 0.0088813 |
| HDGFL1 | 0.0088668 |
| SCUBE3 | 0.0088218 |
| FIP1L1 | 0.0088188 |
| SENP5 | 0.0087887 |
| GNL2 | 0.0087886 |
| RPL32 | 0.0087883 |
| TMEM86B | 0.0087806 |
| KCTD11 | 0.0087714 |
| MT1E | 0.0087614 |
| FIG4 | 0.0087338 |
| PTGES2 | 0.0087316 |
| GPCPD1 | 0.0087049 |
| PRCC | 0.0086926 |
| TRIOBP | 0.0086540 |
| ERICH1 | 0.0086296 |
| LCE2A | 0.0086004 |
| TMED1 | 0.0085370 |
| MCTP2 | 0.0085233 |
| POLR2J2 | 0.0085175 |
| KLRF1 | 0.0085078 |
| SNRPD2 | 0.0085012 |
| MOB1B | 0.0084996 |
| RAD23A | 0.0084948 |
| MERTK | 0.0084898 |
| PRKCD | 0.0084858 |
| FRMD4A | 0.0084688 |
| SYT3 | 0.0084582 |
| ZNF783 | 0.0084447 |
| HIST1H3J | 0.0084183 |
| GLRX5 | 0.0083734 |
| MRPL51 | 0.0083381 |
| HNRNPA3 | 0.0083119 |
| C15orf62 | 0.0083105 |
| NFYC | 0.0082809 |
| MUL1 | 0.0082260 |
| ABCF2 | 0.0082214 |
| ATP6V1F | 0.0082206 |
| POLR1B | 0.0081952 |
| ROBO3 | 0.0081896 |
| P4HA1 | 0.0081778 |
| SLC25A51 | 0.0081697 |
| UBE2J2 | 0.0081609 |
| GNAS | 0.0081432 |
| ZSCAN10 | 0.0081023 |
| C5orf27 | 0.0080400 |
| QRSL1 | 0.0080303 |
| ARHGAP19 | 0.0080123 |
| ATP13A5 | 0.0080031 |
| RHNO1 | 0.0079895 |
| CMTR2 | 0.0079852 |
| ZNF296 | 0.0079707 |
| EEF1A1 | 0.0079679 |
| SUPT6H | 0.0079571 |
| TBC1D10B | 0.0079528 |
| TF | 0.0079515 |
| PANK2 | 0.0079226 |
| ST13 | 0.0078988 |
| BRI3BP | 0.0078823 |
| LZTR1 | 0.0078639 |
| HNRNPF | 0.0078508 |
| SPIN4 | 0.0078444 |
| DCT | 0.0077996 |
| SLC45A2 | 0.0077510 |
| RTKN | 0.0077188 |
| ATXN1 | 0.0076735 |
| MAMLD1 | 0.0076649 |
| C3orf22 | 0.0076053 |
| VSIG1 | 0.0075908 |
| RNF8 | 0.0075898 |
| ITPRIPL2 | 0.0075820 |
| ZNF525 | 0.0075692 |
| CCT8 | 0.0075582 |
| TCHH | 0.0075469 |
| PPID | 0.0074837 |
| H2AFB2 | 0.0074763 |
| FBXO22 | 0.0074291 |
| THY1 | 0.0074254 |
| TXNL4A | 0.0073904 |
| ARVCF | 0.0073870 |
| ZNF319 | 0.0073538 |
| OPRK1 | 0.0073529 |
| SETD5 | 0.0073465 |
| CCDC169 | 0.0073260 |
| PIP | 0.0073045 |
| EXTL3 | 0.0073003 |
| C1orf74 | 0.0072896 |
| RBM10 | 0.0072833 |
| ACIN1 | 0.0072783 |
| C2orf74 | 0.0072735 |
| ALX4 | 0.0072450 |
| CACNG3 | 0.0072393 |
| PPY | 0.0072353 |
| MMP13 | 0.0072328 |
| TTBK1 | 0.0071893 |
| ANKS4B | 0.0071784 |
| ATP5A1 | 0.0071673 |
| KCNJ15 | 0.0071608 |
| TGDS | 0.0071573 |
| PARS2 | 0.0071501 |
| FAM50A | 0.0071467 |
| CACNG5 | 0.0071419 |
| DRP2 | 0.0071331 |
| XRCC3 | 0.0071280 |
| LMF1 | 0.0070970 |
| SGK494 | 0.0070724 |
| NLRP14 | 0.0070638 |
| WDR59 | 0.0070637 |
| DYRK1B | 0.0070591 |
| SLC39A2 | 0.0069981 |
| RPL5 | 0.0069674 |
| GRAP2 | 0.0069666 |
| CHAT | 0.0069375 |
| DUSP9 | 0.0069369 |
| SNX11 | 0.0069352 |
| LIPC | 0.0069121 |
| EMP1 | 0.0068720 |
| KRTDAP | 0.0068399 |
| FSCN1 | 0.0067777 |
| STYX | 0.0067554 |
| PINLYP | 0.0067275 |
| SNRNP48 | 0.0067206 |
| ATP13A3 | 0.0067087 |
| PRPF4B | 0.0066882 |
| DYNLL1 | 0.0066797 |
| ELAVL1 | 0.0066753 |
| PROP1 | 0.0066723 |
| CEBPD | 0.0066692 |
| RNF121 | 0.0066481 |
| STAU1 | 0.0066434 |
| TADA3 | 0.0066391 |
| WDR64 | 0.0066287 |
| TMEM200A | 0.0065203 |
| G6PD | 0.0065119 |
| MTPN | 0.0064985 |
| PFKFB4 | 0.0064856 |
| ZNF786 | 0.0064663 |
| GRWD1 | 0.0063911 |
| PRB4 | 0.0063899 |
| GGACT | 0.0063890 |
| WBP4 | 0.0063836 |
| MAML2 | 0.0063787 |
| ALOX12 | 0.0063620 |
| TBL1XR1 | 0.0063498 |
| FBLN1 | 0.0063495 |
| UBE2F | 0.0063075 |
| PSIP1 | 0.0062877 |
| SYNE1 | 0.0062852 |
| CELA2A | 0.0062638 |
| TRPM5 | 0.0062624 |
| GPR45 | 0.0062544 |
| PPM1F | 0.0062501 |
| SFXN4 | 0.0062399 |
| MMS19 | 0.0062015 |
| NMD3 | 0.0061995 |
| OTUD6A | 0.0061805 |
| NEB | 0.0061793 |
| ALPI | 0.0061761 |
| TRIML2 | 0.0061733 |
| RAB11FIP4 | 0.0061679 |
| DDX6 | 0.0061616 |
| SUGP1 | 0.0061602 |
| VSTM2L | 0.0061571 |
| ICT1 | 0.0061539 |
| LRRC40 | 0.0061358 |
| EBPL | 0.0061343 |
| GJA5 | 0.0061175 |
| NDUFB2 | 0.0061136 |
| REG1B | 0.0060694 |
| RPL27 | 0.0060674 |
| GFM1 | 0.0060668 |
| ARHGAP21 | 0.0060483 |
| IQGAP2 | 0.0060459 |
| STAT5B | 0.0060344 |
| GABRQ | 0.0060340 |
| UGT3A2 | 0.0059946 |
| RBPJ | 0.0059819 |
| OR5A1 | 0.0059807 |
| SETX | 0.0059761 |
| ZNF200 | 0.0059748 |
| TNFRSF11A | 0.0059727 |
| TMEM107 | 0.0059350 |
| ANKDD1A | 0.0059328 |
| CUL4B | 0.0059270 |
| SLC32A1 | 0.0059225 |
| GNPDA1 | 0.0059097 |
| ST3GAL2 | 0.0059066 |
| GPR156 | 0.0059036 |
| NDUFV2 | 0.0058987 |
| C10orf12 | 0.0058847 |
| CBLL1 | 0.0058815 |
| PVRL3 | 0.0058722 |
| PDLIM3 | 0.0058253 |
| ZC3H15 | 0.0058027 |
| AQP8 | 0.0058011 |
| SKIV2L | 0.0057929 |
| CBX1 | 0.0057581 |
| APOC4 | 0.0057347 |
| ENTPD7 | 0.0057335 |
| EPB41L3 | 0.0057122 |
| PIGW | 0.0057075 |
| UPF1 | 0.0056930 |
| PPARG | 0.0056826 |
| NUDC | 0.0056639 |
| PGRMC2 | 0.0056633 |
| ZFAT | 0.0056604 |
| TPRA1 | 0.0056590 |
| KDM4A | 0.0056101 |
| TFAM | 0.0056083 |
| RALBP1 | 0.0055698 |
| RNF214 | 0.0055597 |
| ATP4A | 0.0055581 |
| TBCD | 0.0055544 |
| TFE3 | 0.0055392 |
| DLST | 0.0055355 |
| ZBTB17 | 0.0055345 |
| PLA2G4D | 0.0055185 |
| BTNL3 | 0.0055062 |
| SETDB1 | 0.0054830 |
| CAMK4 | 0.0054811 |
| ATG4C | 0.0054741 |
| EDC4 | 0.0054590 |
| SLC3A1 | 0.0054522 |
| ZIC4 | 0.0054484 |
| BRIP1 | 0.0054199 |
| C10orf11 | 0.0053958 |
| TSC22D4 | 0.0053749 |
| RAX | 0.0053662 |
| PCGF2 | 0.0053641 |
| DYM | 0.0053179 |
| LGI2 | 0.0053096 |
| RNF185 | 0.0052986 |
| FKBP8 | 0.0052948 |
| PCDHB8 | 0.0052761 |
| TMEM220 | 0.0052648 |
| ALDH9A1 | 0.0052388 |
| METTL2A | 0.0051905 |
| MLXIPL | 0.0051822 |
| R3HDM1 | 0.0051808 |
| UTRN | 0.0051795 |
| USP48 | 0.0051778 |
| RABAC1 | 0.0051717 |
| RORA | 0.0051300 |
| SRSF9 | 0.0050943 |
| ZBTB8OS | 0.0050922 |
| DOCK3 | 0.0050777 |
| AHR | 0.0050683 |
| G3BP1 | 0.0050483 |
| STX10 | 0.0050283 |
| CT47A11 | 0.0050020 |
| C2CD2 | 0.0049874 |
| STAB1 | 0.0049808 |
| LAMP2 | 0.0049745 |
| KLHL25 | 0.0049468 |
| PRDX6 | 0.0048910 |
| SLC22A3 | 0.0048832 |
| IQGAP1 | 0.0048736 |
| OR10P1 | 0.0048562 |
| RBM18 | 0.0048104 |
| NRGN | 0.0047906 |
| SLC6A5 | 0.0047806 |
| FAT2 | 0.0047586 |
| PTPLB | 0.0047380 |
| CCL1 | 0.0047336 |
| GLTPD2 | 0.0047155 |
| NR5A1 | 0.0047102 |
| C1orf186 | 0.0047072 |
| HSD17B6 | 0.0046198 |
| GAL3ST4 | 0.0046188 |
| ZNF502 | 0.0046128 |
| HINT3 | 0.0046061 |
| PPAP2B | 0.0046020 |
| USP12 | 0.0045915 |
| SPATA13 | 0.0045897 |
| GPAT2 | 0.0045628 |
| NME9 | 0.0045460 |
| TMEM161A | 0.0045445 |
| RBM15 | 0.0045295 |
| ABCD2 | 0.0045142 |
| POPDC3 | 0.0045122 |
| C14orf166 | 0.0045018 |
| EVPL | 0.0044941 |
| FOXC2 | 0.0044398 |
| TUBB4B | 0.0043878 |
| LRRC37B | 0.0043829 |
| TH | 0.0043668 |
| KIAA1551 | 0.0043650 |
| TREX2 | 0.0042642 |
| PAF1 | 0.0042595 |
| RHO | 0.0042300 |
| CENPH | 0.0042244 |
| BNIP2 | 0.0042144 |
| MAGEB1 | 0.0041865 |
| FOLR3 | 0.0041700 |
| DNAH14 | 0.0041589 |
| PPP2R1A | 0.0041432 |
| MORN3 | 0.0040980 |
| SPIC | 0.0040966 |
| SLC38A2 | 0.0040921 |
| PQBP1 | 0.0040729 |
| HSP90AB1 | 0.0040662 |
| CHP2 | 0.0040658 |
| FHDC1 | 0.0040583 |
| TNIP2 | 0.0040408 |
| ORAI2 | 0.0040384 |
| NOA1 | 0.0039652 |
| LRRC28 | 0.0039561 |
| DVL2 | 0.0039318 |
| ZNF275 | 0.0039195 |
| DQX1 | 0.0039186 |
| NKAP | 0.0039095 |
| FSD1L | 0.0038963 |
| SLC29A4 | 0.0038914 |
| SPATA32 | 0.0038866 |
| HAUS6 | 0.0038765 |
| AK3 | 0.0038374 |
| PPP1R8 | 0.0038067 |
| ZNF532 | 0.0037617 |
| NUBP1 | 0.0037401 |
| OR10H3 | 0.0037331 |
| ZNF746 | 0.0036197 |
| TAF6L | 0.0036176 |
| KCNA2 | 0.0035804 |
| IMPDH1 | 0.0035667 |
| RGS9BP | 0.0035582 |
| KIAA0226 | 0.0035182 |
| HAND2 | 0.0035090 |
| ADPRM | 0.0034816 |
| ACTA2 | 0.0034318 |
| UBXN1 | 0.0034196 |
| KRT2 | 0.0034080 |
| NSUN6 | 0.0033991 |
| TAF12 | 0.0033676 |
| CCDC155 | 0.0033514 |
| RBM34 | 0.0033432 |
| C20orf144 | 0.0033242 |
| GRAP | 0.0032914 |
| RAB40B | 0.0032858 |
| FBXL8 | 0.0032671 |
| BPI | 0.0032644 |
| ZMAT5 | 0.0031786 |
| KDM5D | 0.0031684 |
| OSR1 | 0.0031586 |
| TTF2 | 0.0031008 |
| RPL3 | 0.0030970 |
| DOPEY1 | 0.0030834 |
| TMPRSS2 | 0.0030812 |
| ERH | 0.0030691 |
| CDC5L | 0.0030601 |
| SAMD4B | 0.0030400 |
| PTH2 | 0.0030368 |
| SORT1 | 0.0030250 |
| EXOC3L4 | 0.0030223 |
| LIG3 | 0.0029747 |
| SCAF1 | 0.0029596 |
| COL18A1 | 0.0029551 |
| TMED2 | 0.0029416 |
| FAM65A | 0.0029356 |
| HIST1H2BF | 0.0029172 |
| ZNF274 | 0.0029028 |
| FAM13A | 0.0028875 |
| COMMD9 | 0.0028840 |
| NFKBIL1 | 0.0028702 |
| PBOV1 | 0.0028560 |
| TFG | 0.0028512 |
| MDN1 | 0.0028466 |
| KCMF1 | 0.0028365 |
| CORO2A | 0.0028321 |
| CYP17A1 | 0.0028281 |
| ACAA1 | 0.0028246 |
| CARD8 | 0.0027828 |
| POP5 | 0.0027754 |
| NEU4 | 0.0027447 |
| SLC25A45 | 0.0027248 |
| FAM90A1 | 0.0027085 |
| PAQR3 | 0.0027061 |
| LRP5L | 0.0027019 |
| EPB41L4A-AS2 | 0.0026933 |
| PAOX | 0.0026878 |
| KHSRP | 0.0026745 |
| SACS | 0.0026200 |
| COMMD8 | 0.0026128 |
| IRX6 | 0.0026031 |
| PIK3CA | 0.0025462 |
| TXNRD3 | 0.0025061 |
| BCL2L13 | 0.0024760 |
| PITHD1 | 0.0024655 |
| LIPH | 0.0024316 |
| PNMA6A | 0.0024062 |
| KLK1 | 0.0023820 |
| SLCO4A1 | 0.0023654 |
| OAZ1 | 0.0023544 |
| C2CD4C | 0.0023516 |
| PKNOX2 | 0.0023094 |
| PGLYRP4 | 0.0022976 |
| CDK11B | 0.0022689 |
| UMODL1 | 0.0022601 |
| ACTR1B | 0.0022591 |
| DPYSL3 | 0.0022323 |
| GLMN | 0.0022295 |
| COX7A2 | 0.0021801 |
| FAM47C | 0.0021784 |
| TMPRSS5 | 0.0021763 |
| TNNT2 | 0.0021375 |
| FADS3 | 0.0021374 |
| NUMB | 0.0021211 |
| PIK3CB | 0.0021133 |
| LYPLA2 | 0.0020676 |
| CYP2F1 | 0.0020315 |
| ZFYVE26 | 0.0020268 |
| STX4 | 0.0020040 |
| PRPS2 | 0.0019956 |
| TJAP1 | 0.0019893 |
| MAP2K4 | 0.0019760 |
| CATSPER1 | 0.0019745 |
| YTHDF1 | 0.0019725 |
| SCLT1 | 0.0019352 |
| ATXN2L | 0.0019233 |
| RASSF9 | 0.0018782 |
| SLC39A8 | 0.0018182 |
| HEATR6 | 0.0018146 |
| ZG16 | 0.0018026 |
| GPATCH1 | 0.0018009 |
| RAD51D | 0.0017924 |
| RARB | 0.0017859 |
| DIRAS3 | 0.0017857 |
| GLOD4 | 0.0017835 |
| ANAPC10 | 0.0017827 |
| NEURL4 | 0.0017762 |
| FXR2 | 0.0017750 |
| DEPDC5 | 0.0017693 |
| PCDH17 | 0.0017567 |
| GOPC | 0.0017530 |
| VPS11 | 0.0017321 |
| ERCC3 | 0.0017317 |
| CTNS | 0.0017124 |
| FAM49B | 0.0017097 |
| UBE2M | 0.0017057 |
| VCY | 0.0017002 |
| ESYT3 | 0.0016929 |
| ZDHHC16 | 0.0016463 |
| OR6K2 | 0.0016139 |
| PHACTR1 | 0.0016117 |
| TSEN15 | 0.0016115 |
| TMEM131 | 0.0015985 |
| KCNK9 | 0.0015800 |
| CBX5 | 0.0015187 |
| UTP11L | 0.0014453 |
| IRF9 | 0.0014122 |
| WSB1 | 0.0014008 |
| SDAD1 | 0.0013979 |
| TLR5 | 0.0013928 |
| IMMT | 0.0013871 |
| ZFPL1 | 0.0013729 |
| UCMA | 0.0013606 |
| H3F3C | 0.0013440 |
| MALT1 | 0.0013365 |
| ACTRT3 | 0.0013334 |
| KIAA1161 | 0.0012822 |
| SLC35F6 | 0.0012429 |
| FAM69A | 0.0012292 |
| OPHN1 | 0.0012232 |
| AMACR | 0.0011952 |
| ACP1 | 0.0011655 |
| SUMO1 | 0.0011405 |
| IMP4 | 0.0011270 |
| ALKBH5 | 0.0011142 |
| NEU1 | 0.0011123 |
| IBSP | 0.0010579 |
| SLC15A2 | 0.0010558 |
| SGTB | 0.0010548 |
| BVES | 0.0010313 |
| HMGXB4 | 0.0009902 |
| UBE2O | 0.0009780 |
| MED4 | 0.0009715 |
| RPL10 | 0.0009538 |
| DDRGK1 | 0.0009396 |
| TAS1R1 | 0.0009221 |
| SPATA3 | 0.0008992 |
| EXOSC2 | 0.0008819 |
| KCNJ12 | 0.0008740 |
| NKX3-2 | 0.0008735 |
| PPIE | 0.0008613 |
| TYK2 | 0.0008541 |
| GOLIM4 | 0.0008259 |
| RPL6 | 0.0008182 |
| ACAD9 | 0.0008099 |
| HADHB | 0.0008011 |
| VKORC1 | 0.0007867 |
| LDOC1L | 0.0007762 |
| ZNF410 | 0.0007760 |
| SMYD5 | 0.0007471 |
| KLK13 | 0.0007370 |
| NRF1 | 0.0007303 |
| GEMIN6 | 0.0007178 |
| HOXA9 | 0.0007066 |
| HDAC4 | 0.0006913 |
| TMEM95 | 0.0006494 |
| MYLK | 0.0006335 |
| MRPL3 | 0.0006294 |
| LPHN2 | 0.0005517 |
| FUT2 | 0.0005418 |
| C11orf68 | 0.0005413 |
| AGTPBP1 | 0.0005344 |
| PARP15 | 0.0005250 |
| HSCB | 0.0004753 |
| ZFR | 0.0004688 |
| ATOX1 | 0.0004486 |
| VNN3 | 0.0004476 |
| PNMA3 | 0.0004476 |
| NSUN4 | 0.0004449 |
| DDX42 | 0.0004301 |
| IPMK | 0.0004177 |
| ZNF879 | 0.0004009 |
| FAXC | 0.0003564 |
| ABCG5 | 0.0003352 |
| IST1 | 0.0003255 |
| OR8U1 | 0.0003220 |
| SAMD8 | 0.0003110 |
| R3HCC1L | 0.0002867 |
| CDC42EP4 | 0.0002633 |
| UTP14A | 0.0002631 |
| ZGPAT | 0.0002434 |
| CDYL | 0.0002315 |
| CALR3 | 0.0002302 |
| LYPD3 | 0.0002199 |
| RSPRY1 | 0.0002100 |
| NDST2 | 0.0002076 |
| UBAP2L | 0.0001986 |
| FRMD3 | 0.0001804 |
| FOXA2 | 0.0001802 |
| PIK3IP1 | 0.0001688 |
| KLK14 | 0.0001566 |
| ZDHHC7 | 0.0001097 |
| DCSTAMP | 0.0001082 |
| FASTKD2 | 0.0000886 |
| TEPP | 0.0000652 |
| SESN2 | 0.0000560 |
| SIKE1 | 0.0000371 |
| SUSD5 | 0.0000300 |
| SNAP29 | 0.0000026 |
| RPL36AL | 0.0000024 |
| C21orf128 | -0.0000112 |
| PIGM | -0.0000233 |
| SNAPC5 | -0.0000411 |
| STARD3NL | -0.0000671 |
| SLC13A2 | -0.0000711 |
| FGFBP2 | -0.0000741 |
| ARL11 | -0.0000796 |
| CUZD1 | -0.0000845 |
| PPP4R2 | -0.0001014 |
| PKHD1L1 | -0.0001061 |
| EPO | -0.0001104 |
| TRIM37 | -0.0001122 |
| NSMCE4A | -0.0001201 |
| GPATCH4 | -0.0001441 |
| ADCK2 | -0.0001705 |
| SMARCA2 | -0.0001742 |
| ALG2 | -0.0001884 |
| HS3ST3A1 | -0.0002555 |
| BEST1 | -0.0002668 |
| CHPF | -0.0002787 |
| FXYD7 | -0.0002809 |
| EPN3 | -0.0002810 |
| GPR63 | -0.0002849 |
| WRAP53 | -0.0003217 |
| CLSTN3 | -0.0003321 |
| ENY2 | -0.0003519 |
| TOR1B | -0.0003539 |
| ALKBH3 | -0.0003826 |
| BARX2 | -0.0004023 |
| BAG5 | -0.0004245 |
| HNRNPH1 | -0.0004387 |
| EFNA3 | -0.0004580 |
| TAB1 | -0.0004842 |
| GUCY1A2 | -0.0005167 |
| HAT1 | -0.0005248 |
| VWCE | -0.0005278 |
| CEPT1 | -0.0005352 |
| TTC38 | -0.0005606 |
| TMCO5A | -0.0005785 |
| NBAS | -0.0006173 |
| RANBP10 | -0.0006328 |
| SIRPB1 | -0.0006492 |
| HM13 | -0.0006727 |
| DIRC2 | -0.0006735 |
| TMEM31 | -0.0006830 |
| APBA1 | -0.0006846 |
| DCLRE1A | -0.0006872 |
| ZNF205 | -0.0007005 |
| THADA | -0.0007011 |
| CRAT | -0.0007037 |
| ZCCHC9 | -0.0007116 |
| GYS1 | -0.0007177 |
| MEF2BNB | -0.0007568 |
| LANCL3 | -0.0007579 |
| H1FOO | -0.0007827 |
| WRN | -0.0007926 |
| MAP4 | -0.0007972 |
| LRRC8A | -0.0007993 |
| ADORA2A | -0.0008383 |
| C11orf85 | -0.0008545 |
| URB1 | -0.0008694 |
| SLC2A12 | -0.0008727 |
| ACVR2A | -0.0008888 |
| OR1L3 | -0.0009015 |
| PYGO2 | -0.0009076 |
| GLTSCR1 | -0.0009104 |
| LAMP1 | -0.0009142 |
| OR10A4 | -0.0009255 |
| DPPA5 | -0.0009574 |
| POLR1A | -0.0009614 |
| MMACHC | -0.0009746 |
| MS4A5 | -0.0009985 |
| CCDC85C | -0.0010357 |
| ZNF628 | -0.0010695 |
| CACNA1S | -0.0010767 |
| ATP8A1 | -0.0010865 |
| EIF2S2 | -0.0010920 |
| KIAA0391 | -0.0010998 |
| ABL1 | -0.0011030 |
| ASXL2 | -0.0011202 |
| ZNF569 | -0.0011330 |
| MITF | -0.0011781 |
| HLTF | -0.0011923 |
| ILKAP | -0.0011982 |
| LAMA1 | -0.0012028 |
| PAPLN | -0.0012054 |
| DTYMK | -0.0012157 |
| MAS1L | -0.0012203 |
| CRK | -0.0012408 |
| IDH3B | -0.0012584 |
| PLA2G6 | -0.0012742 |
| EXOSC9 | -0.0012806 |
| ZNF518B | -0.0012937 |
| STRADA | -0.0013092 |
| MLLT3 | -0.0013149 |
| CHKA | -0.0013346 |
| MED23 | -0.0013382 |
| USP3 | -0.0013416 |
| PRR3 | -0.0013610 |
| ROBO1 | -0.0013737 |
| KCNQ2 | -0.0013862 |
| TBC1D15 | -0.0013912 |
| RTCA | -0.0013936 |
| NAALADL1 | -0.0014076 |
| ARMCX3 | -0.0014091 |
| DIP2A | -0.0014206 |
| PTPRE | -0.0014346 |
| TSKU | -0.0014407 |
| FAU | -0.0014792 |
| CHRM2 | -0.0015048 |
| FBXW5 | -0.0015151 |
| HERC6 | -0.0015385 |
| GUK1 | -0.0015409 |
| C5AR1 | -0.0015420 |
| MRPL1 | -0.0015456 |
| DOCK9 | -0.0015706 |
| SLC47A1 | -0.0016548 |
| CRYBB2 | -0.0016588 |
| PIK3R6 | -0.0016605 |
| GALNT18 | -0.0016785 |
| ZNF496 | -0.0016968 |
| TINF2 | -0.0017065 |
| USP21 | -0.0017163 |
| FHL3 | -0.0017458 |
| INSIG1 | -0.0017943 |
| HP | -0.0017961 |
| MZT1 | -0.0018131 |
| SAR1B | -0.0018399 |
| IL1F10 | -0.0018524 |
| NXF1 | -0.0018564 |
| SRP54 | -0.0018579 |
| ATF7IP | -0.0018674 |
| HSPE1 | -0.0019042 |
| NRP1 | -0.0019320 |
| DDN | -0.0019492 |
| PCDH8 | -0.0019497 |
| TARS2 | -0.0019776 |
| CCNK | -0.0019848 |
| TRIM56 | -0.0019939 |
| SNPH | -0.0020145 |
| AP4M1 | -0.0020205 |
| UBA5 | -0.0020315 |
| ADAMTSL5 | -0.0020471 |
| MRPL52 | -0.0020472 |
| ENTHD1 | -0.0020725 |
| TMEM69 | -0.0021223 |
| MSRA | -0.0021415 |
| FHL2 | -0.0021759 |
| MYPOP | -0.0021842 |
| SH2D4A | -0.0022140 |
| C1orf177 | -0.0022374 |
| GINM1 | -0.0022781 |
| FMO4 | -0.0022807 |
| PDRG1 | -0.0022875 |
| CNOT7 | -0.0022877 |
| IRF2 | -0.0022911 |
| BTBD11 | -0.0023084 |
| ALG9 | -0.0023303 |
| SCN3A | -0.0023430 |
| SCYL3 | -0.0023542 |
| CASP7 | -0.0023646 |
| MAML1 | -0.0023915 |
| NDUFA1 | -0.0023935 |
| FMR1 | -0.0024041 |
| ACOT8 | -0.0024525 |
| FGF13 | -0.0024703 |
| MTMR1 | -0.0024859 |
| MPHOSPH8 | -0.0024957 |
| ZFP64 | -0.0025054 |
| ILVBL | -0.0025219 |
| PLXNC1 | -0.0025385 |
| TPRG1L | -0.0025472 |
| MED20 | -0.0025786 |
| FUS | -0.0025789 |
| C10orf90 | -0.0025861 |
| CGB2 | -0.0025869 |
| SLN | -0.0025912 |
| ACPT | -0.0026314 |
| CCDC127 | -0.0026652 |
| WDR1 | -0.0026789 |
| ITIH1 | -0.0026864 |
| MCRS1 | -0.0027836 |
| RSPH9 | -0.0027856 |
| RPS20 | -0.0027863 |
| ZNF8 | -0.0027937 |
| ZBTB1 | -0.0028246 |
| POLR2I | -0.0028282 |
| ZC3HC1 | -0.0028471 |
| OR52A1 | -0.0028961 |
| HOXD13 | -0.0029132 |
| RCBTB2 | -0.0029252 |
| YY1 | -0.0029332 |
| DPY30 | -0.0029362 |
| RRAD | -0.0029621 |
| ACKR2 | -0.0029668 |
| IDH3A | -0.0029872 |
| CLEC4M | -0.0030389 |
| UTP20 | -0.0030455 |
| ACADM | -0.0030643 |
| DRD5 | -0.0030705 |
| GABPB2 | -0.0030712 |
| NXPH1 | -0.0030748 |
| ZNF398 | -0.0030782 |
| HDHD3 | -0.0031033 |
| WNT1 | -0.0031149 |
| ZNF618 | -0.0031328 |
| FAM206A | -0.0031498 |
| AGTRAP | -0.0031575 |
| HOXD10 | -0.0031794 |
| SFR1 | -0.0032155 |
| TMEM53 | -0.0032399 |
| IRF2BPL | -0.0032459 |
| FAM46A | -0.0032846 |
| TTC31 | -0.0032899 |
| ZNF366 | -0.0032925 |
| CEP89 | -0.0033071 |
| ATP5L | -0.0033144 |
| TMEM194A | -0.0033183 |
| PPP2R1B | -0.0033192 |
| DFNA5 | -0.0033352 |
| KRT74 | -0.0033452 |
| MPO | -0.0033516 |
| SYNDIG1 | -0.0033696 |
| SUZ12 | -0.0034102 |
| GNB1 | -0.0034148 |
| CHERP | -0.0034223 |
| TXLNG | -0.0034539 |
| CAPN3 | -0.0035278 |
| SNX7 | -0.0035279 |
| ZNF485 | -0.0035475 |
| XRCC4 | -0.0035896 |
| PRPF40A | -0.0035913 |
| INS | -0.0036280 |
| CRLF2 | -0.0036314 |
| LMO3 | -0.0036465 |
| PROX1 | -0.0036670 |
| LGALS4 | -0.0036775 |
| PROSER2 | -0.0036827 |
| LAMTOR1 | -0.0037089 |
| PCK2 | -0.0037147 |
| FXR1 | -0.0037223 |
| NPAS3 | -0.0037480 |
| DNAH3 | -0.0037929 |
| HTR3E | -0.0038191 |
| ERAP2 | -0.0038314 |
| RANBP6 | -0.0038406 |
| DNM1 | -0.0038446 |
| RPS27 | -0.0038592 |
| OVOL3 | -0.0038850 |
| TSPYL5 | -0.0039007 |
| CHKB | -0.0039109 |
| ZNF18 | -0.0039529 |
| CTNNBL1 | -0.0039847 |
| DDX41 | -0.0040167 |
| GMPPA | -0.0040199 |
| INSRR | -0.0040417 |
| ACD | -0.0040671 |
| MOCOS | -0.0040872 |
| THUMPD2 | -0.0041179 |
| ACTA1 | -0.0041698 |
| DSG3 | -0.0041739 |
| SCARA5 | -0.0041741 |
| OPA1 | -0.0041942 |
| FBXL4 | -0.0042143 |
| HERPUD2 | -0.0042281 |
| DDX27 | -0.0042298 |
| TERF2 | -0.0042311 |
| SMG9 | -0.0042319 |
| ANGEL1 | -0.0042563 |
| C17orf53 | -0.0042713 |
| CHRM3 | -0.0042887 |
| OSBP | -0.0042896 |
| GPR4 | -0.0043127 |
| TEX29 | -0.0043211 |
| CSGALNACT2 | -0.0043247 |
| BAMBI | -0.0043261 |
| C1orf115 | -0.0043722 |
| VGLL4 | -0.0044121 |
| ALDH16A1 | -0.0044339 |
| TREML1 | -0.0044384 |
| MALSU1 | -0.0044420 |
| EDF1 | -0.0044487 |
| DVL3 | -0.0044866 |
| SLC25A47 | -0.0044940 |
| PARD6G | -0.0044988 |
| PCDHGC5 | -0.0045131 |
| LHX3 | -0.0045218 |
| SFTPA2 | -0.0045225 |
| C14orf80 | -0.0045373 |
| GNB2 | -0.0045822 |
| MYC | -0.0045907 |
| SIAH1 | -0.0046068 |
| RGP1 | -0.0046603 |
| LUM | -0.0047026 |
| UHRF1BP1 | -0.0047081 |
| OR10T2 | -0.0047133 |
| BRWD3 | -0.0047141 |
| KAT7 | -0.0047271 |
| MRPS18B | -0.0047495 |
| FAM160B1 | -0.0047716 |
| PDE6D | -0.0047738 |
| TOMM20L | -0.0047744 |
| NCR1 | -0.0047885 |
| CAMK2G | -0.0047890 |
| SEC24C | -0.0048217 |
| TSPAN18 | -0.0048414 |
| MTTP | -0.0048610 |
| TUSC3 | -0.0048617 |
| ASB1 | -0.0048635 |
| GDPD5 | -0.0048655 |
| FARSA | -0.0048981 |
| LCT | -0.0049165 |
| GTF2H1 | -0.0049652 |
| SEC16B | -0.0049723 |
| PSEN1 | -0.0049730 |
| AHCY | -0.0049842 |
| SPRY2 | -0.0050039 |
| GUCY2C | -0.0050621 |
| MLC1 | -0.0050672 |
| CIC | -0.0050857 |
| CCDC168 | -0.0050968 |
| MTBP | -0.0051063 |
| TAF1C | -0.0051095 |
| CD300LB | -0.0051200 |
| CYP11B1 | -0.0051304 |
| C21orf67 | -0.0051345 |
| C14orf182 | -0.0051387 |
| ZNF133 | -0.0051509 |
| SULT1C2 | -0.0051775 |
| PRMT6 | -0.0051837 |
| ARHGEF7 | -0.0052447 |
| S1PR5 | -0.0052469 |
| VMAC | -0.0052696 |
| RAB15 | -0.0052896 |
| DCTN5 | -0.0052907 |
| HNRNPA1L2 | -0.0053033 |
| TAF8 | -0.0053092 |
| FAM168B | -0.0053237 |
| AP1S1 | -0.0053488 |
| CLEC5A | -0.0053518 |
| LANCL2 | -0.0053550 |
| GAS6 | -0.0054545 |
| PABPC1L2B | -0.0054550 |
| VPS45 | -0.0054791 |
| CHRNB1 | -0.0054799 |
| TPRX1 | -0.0054838 |
| HNRNPD | -0.0054984 |
| DTL | -0.0055345 |
| MAPKAPK5 | -0.0055475 |
| ABR | -0.0055570 |
| PICK1 | -0.0055862 |
| ADAM33 | -0.0056137 |
| H3F3A | -0.0056141 |
| EHMT2 | -0.0056945 |
| GLTP | -0.0057281 |
| SPINK2 | -0.0057494 |
| CLK2 | -0.0057702 |
| ARAF | -0.0057715 |
| C8A | -0.0057722 |
| UQCRC1 | -0.0057768 |
| ITGA1 | -0.0057936 |
| RDM1 | -0.0057990 |
| SCYL2 | -0.0058006 |
| KLF1 | -0.0058036 |
| MMADHC | -0.0058195 |
| FBXO42 | -0.0058888 |
| GTF2F2 | -0.0058919 |
| CLINT1 | -0.0058981 |
| PGBD2 | -0.0058988 |
| FKBP7 | -0.0059056 |
| PUM2 | -0.0059080 |
| GNPTAB | -0.0059258 |
| C9orf72 | -0.0059729 |
| ZNF593 | -0.0059770 |
| OTX1 | -0.0060029 |
| CTBP1 | -0.0060630 |
| CISD3 | -0.0060699 |
| SGCE | -0.0060757 |
| GMEB2 | -0.0061225 |
| VBP1 | -0.0061839 |
| C21orf90 | -0.0061845 |
| TRIP4 | -0.0061936 |
| ZC3H12D | -0.0062112 |
| ABCB7 | -0.0062264 |
| INTS9 | -0.0062469 |
| POU5F2 | -0.0062732 |
| IGSF3 | -0.0062903 |
| FAM135A | -0.0062978 |
| ZNF570 | -0.0063067 |
| KIAA1033 | -0.0063492 |
| MICA | -0.0063517 |
| ASPG | -0.0063528 |
| TMEM62 | -0.0063572 |
| CASQ1 | -0.0063615 |
| NPPB | -0.0064426 |
| BIRC7 | -0.0064701 |
| MYNN | -0.0064738 |
| USP15 | -0.0064808 |
| TIMELESS | -0.0064893 |
| ELOF1 | -0.0064906 |
| SAPCD1 | -0.0064927 |
| CASP14 | -0.0064997 |
| TNFSF15 | -0.0065031 |
| ZSCAN2 | -0.0065192 |
| SUPT16H | -0.0065478 |
| RPUSD4 | -0.0065573 |
| FZD1 | -0.0066090 |
| LENG8 | -0.0066104 |
| C8G | -0.0066353 |
| GFRA2 | -0.0066420 |
| GNB3 | -0.0066422 |
| HIST1H2BD | -0.0066439 |
| DEFA4 | -0.0066535 |
| RNF144A | -0.0066669 |
| ASPDH | -0.0066735 |
| OGFOD3 | -0.0067021 |
| SLC35D3 | -0.0067139 |
| MLF2 | -0.0067295 |
| RPL10A | -0.0067342 |
| CHMP3 | -0.0067407 |
| OLFML1 | -0.0067484 |
| DACT2 | -0.0067491 |
| PLEKHM1 | -0.0067517 |
| ITSN2 | -0.0067934 |
| COL6A2 | -0.0068127 |
| SLC6A19 | -0.0068172 |
| GAST | -0.0068228 |
| SSH1 | -0.0068242 |
| CCR3 | -0.0068305 |
| PPIC | -0.0068496 |
| RECQL | -0.0068557 |
| ZSCAN12 | -0.0068604 |
| C22orf15 | -0.0068777 |
| CPXM2 | -0.0068787 |
| HNRNPUL2 | -0.0068862 |
| PKDREJ | -0.0068916 |
| PPT1 | -0.0069036 |
| DNAL4 | -0.0069084 |
| TNNI1 | -0.0069461 |
| MPL | -0.0069557 |
| TRAIP | -0.0069603 |
| CCDC37 | -0.0069618 |
| DOCK5 | -0.0069748 |
| HECTD3 | -0.0069845 |
| TATDN1 | -0.0070000 |
| C4orf3 | -0.0070009 |
| RNPS1 | -0.0070054 |
| LLGL1 | -0.0070065 |
| MED12 | -0.0070281 |
| MRPL13 | -0.0070526 |
| C2orf49 | -0.0070583 |
| TRIM24 | -0.0070652 |
| MPHOSPH9 | -0.0070722 |
| SH3RF2 | -0.0070858 |
| KAT5 | -0.0071135 |
| FCN2 | -0.0071198 |
| SLC35A5 | -0.0071242 |
| C1orf50 | -0.0071555 |
| WDR92 | -0.0071785 |
| CNTNAP5 | -0.0071799 |
| CRCT1 | -0.0071972 |
| RIMBP3 | -0.0072079 |
| C12orf36 | -0.0072195 |
| PAPL | -0.0072280 |
| MAPK6 | -0.0072512 |
| POU3F3 | -0.0072617 |
| ALKBH2 | -0.0072766 |
| WRAP73 | -0.0072773 |
| TXNRD1 | -0.0073290 |
| DPH5 | -0.0073515 |
| VWA7 | -0.0073572 |
| ARHGEF11 | -0.0073669 |
| ARSE | -0.0074924 |
| CDK2 | -0.0075412 |
| CLPX | -0.0075992 |
| SOX30 | -0.0075996 |
| WNT9B | -0.0076026 |
| FLCN | -0.0076121 |
| GPR34 | -0.0076184 |
| ANKFY1 | -0.0076254 |
| EIF4ENIF1 | -0.0076306 |
| DLEU1 | -0.0076455 |
| C7orf61 | -0.0076742 |
| ERCC1 | -0.0076745 |
| ZNF280B | -0.0076945 |
| RAD54L2 | -0.0077396 |
| CCDC90B | -0.0077754 |
| HMGCS2 | -0.0078417 |
| CNTF | -0.0078569 |
| FARSB | -0.0078711 |
| SNX27 | -0.0078965 |
| GALK1 | -0.0079093 |
| SOAT2 | -0.0079291 |
| S1PR1 | -0.0079577 |
| ALK | -0.0079591 |
| LALBA | -0.0080220 |
| COL4A1 | -0.0080268 |
| DHRSX | -0.0080317 |
| RECK | -0.0080411 |
| OXCT2 | -0.0080419 |
| PRTFDC1 | -0.0080499 |
| PPIA | -0.0080526 |
| CNPY4 | -0.0080565 |
| SLITRK4 | -0.0080609 |
| ACBD5 | -0.0080782 |
| ZNF76 | -0.0080904 |
| CDKN2D | -0.0080966 |
| DNAAF2 | -0.0081007 |
| INPP5F | -0.0081038 |
| TP53INP2 | -0.0081171 |
| NFATC1 | -0.0081220 |
| KRTAP1-3 | -0.0081462 |
| TRIAP1 | -0.0081552 |
| AIRE | -0.0081571 |
| SYMPK | -0.0081647 |
| SRRT | -0.0081867 |
| RPS17 | -0.0082166 |
| DNAJC10 | -0.0082413 |
| KRT28 | -0.0082437 |
| C5orf22 | -0.0082451 |
| GLTPD1 | -0.0082593 |
| YY1AP1 | -0.0082939 |
| PTPN14 | -0.0082993 |
| SMC1A | -0.0083101 |
| ANPEP | -0.0083214 |
| SMYD4 | -0.0083716 |
| LOR | -0.0083732 |
| RNFT1 | -0.0083918 |
| PHACTR4 | -0.0083972 |
| UTP3 | -0.0084002 |
| SERPINA9 | -0.0084020 |
| PDZD11 | -0.0084086 |
| SCFD2 | -0.0084133 |
| PCGF1 | -0.0084161 |
| ERN1 | -0.0084309 |
| DCBLD2 | -0.0084331 |
| C1orf159 | -0.0084623 |
| THBD | -0.0084791 |
| UCKL1 | -0.0084807 |
| CHUK | -0.0084843 |
| AXDND1 | -0.0084873 |
| HNRNPCL1 | -0.0085244 |
| WDR75 | -0.0085392 |
| GLE1 | -0.0085665 |
| TCEB3 | -0.0085791 |
| AMOTL1 | -0.0085951 |
| FAM21A | -0.0086475 |
| GPR157 | -0.0086604 |
| NCBP2 | -0.0086688 |
| LRRC41 | -0.0086806 |
| AP4B1 | -0.0086994 |
| RGS14 | -0.0087000 |
| RBM14 | -0.0087057 |
| U2AF1L4 | -0.0087269 |
| ST5 | -0.0087287 |
| GYG2 | -0.0087343 |
| PUS10 | -0.0087372 |
| MFSD6 | -0.0087520 |
| ANKRD65 | -0.0087652 |
| RNF181 | -0.0088374 |
| RMI1 | -0.0088423 |
| NFRKB | -0.0088693 |
| RGS3 | -0.0088745 |
| TONSL | -0.0088878 |
| KIAA1045 | -0.0089002 |
| ISM2 | -0.0089093 |
| SIRT4 | -0.0089498 |
| SLC7A6OS | -0.0089790 |
| THOC1 | -0.0090219 |
| TRNT1 | -0.0090988 |
| RAP1B | -0.0091182 |
| PCBP1 | -0.0091338 |
| HAUS4 | -0.0091490 |
| TMEM251 | -0.0091499 |
| HOXA10 | -0.0091503 |
| C9orf156 | -0.0091750 |
| IMP3 | -0.0092069 |
| POLR3B | -0.0092177 |
| BASP1 | -0.0092235 |
| RAB1B | -0.0092238 |
| PHF6 | -0.0092447 |
| UPK1A | -0.0092772 |
| PLRG1 | -0.0092871 |
| AMIGO3 | -0.0092876 |
| ELOVL4 | -0.0093373 |
| OR8H1 | -0.0093428 |
| ARHGAP11A | -0.0093536 |
| KIAA1143 | -0.0093782 |
| RPS21 | -0.0093790 |
| NOX1 | -0.0094080 |
| PAXBP1 | -0.0094586 |
| POLR3G | -0.0094611 |
| FARP1 | -0.0094785 |
| FERMT1 | -0.0094833 |
| DMRT3 | -0.0094921 |
| OCRL | -0.0095044 |
| DCST1 | -0.0095168 |
| IGSF5 | -0.0095364 |
| IFITM10 | -0.0095413 |
| INIP | -0.0095551 |
| CFB | -0.0095589 |
| MMP20 | -0.0095656 |
| C17orf77 | -0.0095715 |
| TAZ | -0.0096136 |
| ESRP1 | -0.0096197 |
| HAND1 | -0.0096283 |
| USMG5 | -0.0096365 |
| TERT | -0.0096632 |
| PHIP | -0.0096771 |
| MLX | -0.0096974 |
| TAF10 | -0.0097100 |
| ADD3 | -0.0097295 |
| POMP | -0.0097436 |
| SVIL | -0.0097591 |
| FIGN | -0.0097741 |
| MYO5A | -0.0097923 |
| ATG2A | -0.0098016 |
| POLR3F | -0.0098083 |
| GAS2L3 | -0.0098119 |
| OXSR1 | -0.0098347 |
| GADD45G | -0.0098376 |
| ZFP82 | -0.0098632 |
| SIN3B | -0.0098880 |
| GGA3 | -0.0098947 |
| ZBTB25 | -0.0099429 |
| FIBCD1 | -0.0099431 |
| CELA1 | -0.0099488 |
| ZNF579 | -0.0099722 |
| PSG2 | -0.0099795 |
| ABL2 | -0.0099863 |
| SCGB2B2 | -0.0100008 |
| ACP6 | -0.0100150 |
| SNAPC4 | -0.0100519 |
| TSN | -0.0100619 |
| CEP170 | -0.0100841 |
| C7orf55 | -0.0100903 |
| C6orf89 | -0.0101082 |
| IL12B | -0.0101123 |
| FGF11 | -0.0101463 |
| OR1D5 | -0.0101680 |
| KCNJ1 | -0.0101978 |
| ABCA1 | -0.0102020 |
| UXT | -0.0102031 |
| ZNF2 | -0.0102062 |
| ROR1 | -0.0102135 |
| UBLCP1 | -0.0102204 |
| PRRG4 | -0.0102265 |
| PRMT5 | -0.0102309 |
| ACBD4 | -0.0102466 |
| CIDEB | -0.0102570 |
| NT5DC1 | -0.0102805 |
| POU4F2 | -0.0102936 |
| KAZN | -0.0103026 |
| H1FX | -0.0103144 |
| ARHGEF18 | -0.0103645 |
| PLGRKT | -0.0103660 |
| RBMX | -0.0103989 |
| RAB23 | -0.0104273 |
| MAST2 | -0.0104706 |
| CIZ1 | -0.0105012 |
| GHRH | -0.0105059 |
| RPL36A | -0.0105778 |
| IFIT5 | -0.0105894 |
| CDC27 | -0.0105970 |
| XXYLT1 | -0.0106196 |
| SNAP47 | -0.0106296 |
| ARL8B | -0.0106313 |
| PLXNB3 | -0.0106645 |
| ANKRD17 | -0.0106686 |
| RBM4 | -0.0106816 |
| AGO1 | -0.0107026 |
| MAGEF1 | -0.0107381 |
| ABCC4 | -0.0107479 |
| ABHD11 | -0.0107526 |
| ARIH1 | -0.0107605 |
| NR1H2 | -0.0107616 |
| SPG20OS | -0.0107724 |
| CHRNB3 | -0.0107807 |
| MRPL33 | -0.0107816 |
| COX5B | -0.0108047 |
| CDC37L1 | -0.0108047 |
| FAM45A | -0.0108068 |
| PSMA1 | -0.0108092 |
| UNC93A | -0.0108216 |
| PEF1 | -0.0108252 |
| ACER1 | -0.0108427 |
| HSD3B2 | -0.0108452 |
| IL1RAPL2 | -0.0108460 |
| PPP3R1 | -0.0108517 |
| HOMER1 | -0.0108613 |
| GPR75 | -0.0108633 |
| TNFSF12 | -0.0108754 |
| GDF2 | -0.0108912 |
| KLHDC7A | -0.0109568 |
| P2RY2 | -0.0110106 |
| DIAPH2 | -0.0110292 |
| KIF24 | -0.0110332 |
| NR2E1 | -0.0110519 |
| API5 | -0.0110717 |
| NOTUM | -0.0110903 |
| EPGN | -0.0110949 |
| SPERT | -0.0111050 |
| MTMR3 | -0.0111107 |
| TMCO2 | -0.0111410 |
| TRAPPC4 | -0.0111619 |
| RAD54B | -0.0111777 |
| ZDHHC3 | -0.0111888 |
| BSND | -0.0111928 |
| SMTNL2 | -0.0111960 |
| KLHL5 | -0.0112170 |
| TMEM155 | -0.0112530 |
| P2RY12 | -0.0112713 |
| UCN2 | -0.0112905 |
| DHX8 | -0.0112964 |
| PADI1 | -0.0113204 |
| GNL3L | -0.0113337 |
| ZBTB34 | -0.0113640 |
| MTHFSD | -0.0113772 |
| MVB12B | -0.0113998 |
| POLR3H | -0.0114148 |
| VAMP2 | -0.0114165 |
| TRMT2B | -0.0114509 |
| RXFP4 | -0.0114569 |
| JUP | -0.0114755 |
| PIK3C2B | -0.0114765 |
| USP17L25 | -0.0114840 |
| PPP5C | -0.0114892 |
| SETDB2 | -0.0114958 |
| KDM3A | -0.0114987 |
| CACNB1 | -0.0115033 |
| PRKAG1 | -0.0115041 |
| MRRF | -0.0115255 |
| FCAR | -0.0115272 |
| IFRD2 | -0.0115295 |
| SEC61A2 | -0.0115329 |
| F2RL3 | -0.0115942 |
| NKIRAS1 | -0.0116300 |
| FAM199X | -0.0116384 |
| METTL23 | -0.0116475 |
| AURKAIP1 | -0.0116676 |
| TSEN34 | -0.0116690 |
| DCAF11 | -0.0116768 |
| NDUFA12 | -0.0116778 |
| PROKR1 | -0.0116813 |
| UAP1L1 | -0.0117169 |
| NDOR1 | -0.0117537 |
| FASTKD3 | -0.0117539 |
| POLR3GL | -0.0117761 |
| PRRC2B | -0.0118076 |
| IL5RA | -0.0118508 |
| FOSL2 | -0.0118555 |
| EBNA1BP2 | -0.0118702 |
| RPTOR | -0.0118823 |
| LYZL1 | -0.0118972 |
| WFDC5 | -0.0119238 |
| HSF5 | -0.0119276 |
| PPP1R2 | -0.0119426 |
| SLC12A4 | -0.0119647 |
| EIF5A2 | -0.0120047 |
| TCF23 | -0.0120138 |
| C7orf31 | -0.0120343 |
| EFEMP1 | -0.0120416 |
| YWHAG | -0.0120457 |
| ZNF562 | -0.0120765 |
| RBM8A | -0.0121025 |
| XAGE3 | -0.0121079 |
| NKX6-3 | -0.0121082 |
| SLC26A7 | -0.0121089 |
| FSD1 | -0.0121295 |
| NTRK1 | -0.0121490 |
| C1RL | -0.0121705 |
| NOL4 | -0.0121713 |
| CKB | -0.0121966 |
| PCNT | -0.0122049 |
| BOC | -0.0122222 |
| PAK2 | -0.0122348 |
| ZNF383 | -0.0122487 |
| C20orf201 | -0.0122565 |
| EPHA2 | -0.0122697 |
| KRT76 | -0.0122756 |
| UBA6 | -0.0123053 |
| TREH | -0.0123076 |
| CENPV | -0.0123535 |
| HMG20B | -0.0123656 |
| CSN1S1 | -0.0123681 |
| SIX3 | -0.0123757 |
| RAPGEF5 | -0.0123764 |
| HIST1H4A | -0.0123812 |
| ZNF142 | -0.0123921 |
| C10orf76 | -0.0124096 |
| TMED7-TICAM2 | -0.0124245 |
| TFB2M | -0.0124365 |
| IL17A | -0.0124554 |
| OR10H4 | -0.0124659 |
| SIMC1 | -0.0124717 |
| MPLKIP | -0.0124974 |
| SNX14 | -0.0125060 |
| KHK | -0.0125087 |
| TTLL12 | -0.0125295 |
| ARNT | -0.0125390 |
| NDUFA3 | -0.0125587 |
| SLC25A21 | -0.0125665 |
| GPD2 | -0.0125750 |
| CD200R1 | -0.0126432 |
| MYBPC1 | -0.0126742 |
| CEP85 | -0.0126745 |
| PHOX2A | -0.0126792 |
| GCDH | -0.0126852 |
| HNRNPR | -0.0126954 |
| TAMM41 | -0.0126988 |
| HES7 | -0.0127219 |
| TBL2 | -0.0127257 |
| RDH14 | -0.0127586 |
| PPAT | -0.0127594 |
| ULK1 | -0.0127644 |
| PHB2 | -0.0127673 |
| FAM170A | -0.0127678 |
| SHISA5 | -0.0127983 |
| GDPD2 | -0.0127994 |
| BRD1 | -0.0128328 |
| SRSF5 | -0.0128426 |
| TXN2 | -0.0128529 |
| MRGPRE | -0.0128686 |
| DUSP23 | -0.0128747 |
| RPAIN | -0.0128785 |
| PLEKHB2 | -0.0129099 |
| CDC42EP2 | -0.0129288 |
| ZFAND2B | -0.0129467 |
| CDK11A | -0.0129494 |
| WASF2 | -0.0129779 |
| LSM14B | -0.0129802 |
| BET1 | -0.0130080 |
| TMEM255B | -0.0130240 |
| FAM105A | -0.0130293 |
| BCL10 | -0.0130293 |
| DTX4 | -0.0130540 |
| CDK5RAP1 | -0.0130890 |
| HRH2 | -0.0130894 |
| GPR31 | -0.0130988 |
| TMX2 | -0.0131083 |
| ZNFX1 | -0.0131089 |
| DENND1A | -0.0131211 |
| GPR113 | -0.0131267 |
| CCDC42B | -0.0131282 |
| OR1E1 | -0.0131505 |
| WDR3 | -0.0131564 |
| CYP4A11 | -0.0131835 |
| EIF2B4 | -0.0131947 |
| ST8SIA2 | -0.0131993 |
| SKIL | -0.0132012 |
| PRKCSH | -0.0132025 |
| PACRG | -0.0132202 |
| FAM3C | -0.0132373 |
| NKIRAS2 | -0.0132503 |
| MOSPD2 | -0.0132814 |
| FAM9C | -0.0132909 |
| RBMXL1 | -0.0132997 |
| TRIM31 | -0.0133016 |
| C9orf92 | -0.0133101 |
| PRSS21 | -0.0133128 |
| NXPE4 | -0.0133438 |
| OR10J3 | -0.0133468 |
| COMMD7 | -0.0133528 |
| NR6A1 | -0.0133549 |
| SLC30A6 | -0.0133633 |
| CCAR1 | -0.0133821 |
| CCR4 | -0.0133885 |
| SMIM2 | -0.0134000 |
| SYN1 | -0.0134045 |
| APTX | -0.0134306 |
| LIMS2 | -0.0134353 |
| SLC38A7 | -0.0134368 |
| GBA2 | -0.0134413 |
| RAB12 | -0.0134437 |
| ACSM3 | -0.0134612 |
| IMPG2 | -0.0134748 |
| VDAC2 | -0.0134780 |
| AKNA | -0.0134806 |
| TMEM52B | -0.0135098 |
| DUOXA2 | -0.0135187 |
| PGBD5 | -0.0135340 |
| TRPC6 | -0.0135341 |
| PTCH2 | -0.0135484 |
| SHANK1 | -0.0135508 |
| CERS3 | -0.0135681 |
| EIF2B1 | -0.0135763 |
| EIF3M | -0.0135768 |
| CYP2S1 | -0.0135967 |
| PDLIM7 | -0.0136035 |
| OTUD4 | -0.0136123 |
| C7orf43 | -0.0136231 |
| TICAM1 | -0.0136271 |
| C2orf44 | -0.0136440 |
| MRPS14 | -0.0136768 |
| SLC39A14 | -0.0136905 |
| MYO3A | -0.0137090 |
| C14orf142 | -0.0137175 |
| SNUPN | -0.0137219 |
| EIF3B | -0.0137790 |
| SIX5 | -0.0138183 |
| SLC34A1 | -0.0138337 |
| SLC12A7 | -0.0138643 |
| PEAR1 | -0.0138685 |
| TCERG1 | -0.0138798 |
| SPINK6 | -0.0138926 |
| EMG1 | -0.0138937 |
| ARHGEF19 | -0.0139011 |
| TRIM46 | -0.0139060 |
| DUSP1 | -0.0139140 |
| CTTNBP2NL | -0.0139153 |
| CAMK1 | -0.0139253 |
| DHRS3 | -0.0139319 |
| KCTD8 | -0.0139702 |
| OR51B5 | -0.0139897 |
| PIAS1 | -0.0140076 |
| CYP2C18 | -0.0140207 |
| UBE3D | -0.0140218 |
| CST1 | -0.0140227 |
| LRRTM1 | -0.0140234 |
| DENR | -0.0140454 |
| HTATIP2 | -0.0140460 |
| BBS7 | -0.0140612 |
| UBQLN3 | -0.0140614 |
| PIGU | -0.0140628 |
| TMX1 | -0.0140655 |
| PRCD | -0.0140785 |
| GYLTL1B | -0.0140811 |
| BTNL8 | -0.0140835 |
| PALMD | -0.0140870 |
| FAM83A | -0.0140997 |
| YARS2 | -0.0141097 |
| GPR39 | -0.0141293 |
| MESDC1 | -0.0141558 |
| EHMT1 | -0.0141566 |
| NDUFS3 | -0.0141575 |
| GTF2A1 | -0.0141628 |
| DISC1 | -0.0141683 |
| FOXG1 | -0.0142231 |
| TEX101 | -0.0142287 |
| LPL | -0.0142402 |
| ARHGAP12 | -0.0142464 |
| ZDHHC19 | -0.0142518 |
| SOX2 | -0.0142568 |
| ANAPC5 | -0.0143049 |
| OXSM | -0.0143190 |
| GPX2 | -0.0143273 |
| RAD23B | -0.0143924 |
| CNIH1 | -0.0144047 |
| MVP | -0.0144270 |
| SAMD1 | -0.0144341 |
| RNF175 | -0.0144411 |
| TRIO | -0.0144517 |
| DDX23 | -0.0144641 |
| ZNF469 | -0.0144750 |
| SLC28A1 | -0.0145234 |
| ENTHD2 | -0.0145524 |
| REST | -0.0145645 |
| NKX2-1 | -0.0145720 |
| KRTAP4-6 | -0.0145810 |
| CCDC120 | -0.0146020 |
| CASC5 | -0.0146092 |
| USP43 | -0.0146114 |
| BTC | -0.0146457 |
| ZNF32 | -0.0146464 |
| BEND4 | -0.0146805 |
| CCL15 | -0.0146872 |
| HSD11B1L | -0.0146876 |
| HMGN2 | -0.0147342 |
| FAM212A | -0.0147510 |
| NDUFV3 | -0.0147538 |
| LSM5 | -0.0147563 |
| IL2 | -0.0147666 |
| TNFRSF13B | -0.0147677 |
| SRCIN1 | -0.0147771 |
| EIF6 | -0.0147906 |
| NEUROG2 | -0.0148101 |
| DOLK | -0.0148197 |
| MTG2 | -0.0148308 |
| GTF2B | -0.0148638 |
| ALKBH6 | -0.0148702 |
| TSEN54 | -0.0148718 |
| CD276 | -0.0148786 |
| CBX7 | -0.0148855 |
| MAPK11 | -0.0148904 |
| LACTBL1 | -0.0148911 |
| UPK1B | -0.0148957 |
| TBC1D10A | -0.0149292 |
| FSHR | -0.0149365 |
| C16orf86 | -0.0149415 |
| KRTAP4-5 | -0.0149760 |
| PROKR2 | -0.0150027 |
| FOLR4 | -0.0150342 |
| RYR3 | -0.0150493 |
| NDUFA13 | -0.0150495 |
| ZNF622 | -0.0150607 |
| LRRC63 | -0.0150707 |
| PSME1 | -0.0150915 |
| CDK2AP2 | -0.0150941 |
| NDUFB3 | -0.0150948 |
| SPAST | -0.0151006 |
| PTPN4 | -0.0151040 |
| SMPX | -0.0151083 |
| LUZP1 | -0.0151093 |
| DCLRE1B | -0.0151309 |
| MYEOV | -0.0151432 |
| ZDHHC13 | -0.0151582 |
| TMUB1 | -0.0151661 |
| ARL16 | -0.0151854 |
| CMTM1 | -0.0151861 |
| C17orf85 | -0.0152140 |
| ETV3L | -0.0152701 |
| LTBR | -0.0152780 |
| WBSCR16 | -0.0152817 |
| C2orf48 | -0.0152862 |
| GRM5 | -0.0152957 |
| ENDOG | -0.0153782 |
| TAS2R16 | -0.0153819 |
| CCDC93 | -0.0153828 |
| ITCH | -0.0153931 |
| ALG12 | -0.0153976 |
| EPHB1 | -0.0154105 |
| VIPAS39 | -0.0154143 |
| HADHA | -0.0154522 |
| LGALS1 | -0.0154618 |
| OTOP2 | -0.0154670 |
| OXCT1 | -0.0154900 |
| MAP3K13 | -0.0154926 |
| IFNB1 | -0.0154939 |
| ARFRP1 | -0.0154991 |
| CALHM1 | -0.0155000 |
| TULP1 | -0.0155235 |
| BTN1A1 | -0.0155298 |
| NT5C3B | -0.0155398 |
| HYLS1 | -0.0155505 |
| AP5B1 | -0.0155525 |
| AAK1 | -0.0156018 |
| MRPL35 | -0.0156238 |
| PURB | -0.0156408 |
| DNASE1L1 | -0.0156711 |
| L3MBTL4 | -0.0156729 |
| NOC4L | -0.0156733 |
| FAM111A | -0.0156891 |
| APRT | -0.0157222 |
| KRTAP3-1 | -0.0157285 |
| C5orf55 | -0.0157596 |
| RAB39A | -0.0157859 |
| OR2AP1 | -0.0157935 |
| OAF | -0.0158081 |
| CAMK1G | -0.0158095 |
| SLC35F5 | -0.0158201 |
| TTLL1 | -0.0158376 |
| AGK | -0.0158475 |
| PASD1 | -0.0158476 |
| C20orf27 | -0.0158528 |
| SFMBT1 | -0.0158617 |
| FAM131A | -0.0159208 |
| TMEM63A | -0.0159340 |
| ZNF330 | -0.0159413 |
| NPY4R | -0.0159425 |
| CCDC97 | -0.0159680 |
| MTMR6 | -0.0159783 |
| IKZF2 | -0.0160145 |
| KCNH4 | -0.0160145 |
| C8orf58 | -0.0160453 |
| CDH5 | -0.0160460 |
| MRPS11 | -0.0160520 |
| TAF2 | -0.0160538 |
| SNX15 | -0.0160595 |
| SPECC1L | -0.0160608 |
| GEMIN2 | -0.0160897 |
| LRRC18 | -0.0160948 |
| TPTE | -0.0161397 |
| ZNF202 | -0.0161489 |
| TCTE3 | -0.0161610 |
| HDAC8 | -0.0161698 |
| STXBP5 | -0.0161780 |
| FNDC3A | -0.0161954 |
| AASDHPPT | -0.0161958 |
| CTGF | -0.0162048 |
| IZUMO2 | -0.0162193 |
| PDE6H | -0.0162336 |
| MSC | -0.0162466 |
| C9orf85 | -0.0162481 |
| UROS | -0.0162557 |
| ICMT | -0.0162783 |
| OR5AP2 | -0.0162810 |
| ZC3H4 | -0.0162852 |
| CDH4 | -0.0162911 |
| ZP2 | -0.0162913 |
| C21orf59 | -0.0162923 |
| GNG2 | -0.0162979 |
| SMARCE1 | -0.0163069 |
| LPA | -0.0163083 |
| MIER1 | -0.0163205 |
| DYNC1LI2 | -0.0163247 |
| AVL9 | -0.0163861 |
| CCDC18 | -0.0164097 |
| LRRFIP2 | -0.0164233 |
| C2CD2L | -0.0164422 |
| SIGLEC11 | -0.0164465 |
| HIF3A | -0.0164546 |
| ACACA | -0.0164973 |
| ATP5E | -0.0165121 |
| FOSL1 | -0.0165243 |
| CLPP | -0.0165245 |
| ATXN1L | -0.0165264 |
| PADI3 | -0.0165519 |
| CLCNKA | -0.0165528 |
| DUOX2 | -0.0165555 |
| PIGY | -0.0165821 |
| MANBA | -0.0166071 |
| INO80D | -0.0166196 |
| ARL2 | -0.0166303 |
| SUMF2 | -0.0166378 |
| PCBP4 | -0.0166641 |
| TRPC4AP | -0.0166928 |
| TADA1 | -0.0167363 |
| GPR37 | -0.0167411 |
| RFPL3S | -0.0167472 |
| TAF1D | -0.0167634 |
| RBFOX2 | -0.0167689 |
| PAGE1 | -0.0167783 |
| LECT1 | -0.0167814 |
| RPS8 | -0.0167847 |
| ZNF70 | -0.0167978 |
| C6orf164 | -0.0168105 |
| PPP2R5B | -0.0168165 |
| CLEC12B | -0.0168602 |
| C1orf52 | -0.0168938 |
| MS4A7 | -0.0169093 |
| GEN1 | -0.0169266 |
| TRMT12 | -0.0169950 |
| MTIF3 | -0.0169961 |
| INPP5B | -0.0170017 |
| SLC24A4 | -0.0170025 |
| GCC1 | -0.0170101 |
| KRTAP9-2 | -0.0170334 |
| PNMAL2 | -0.0170417 |
| NHLRC2 | -0.0170759 |
| B4GALT7 | -0.0170982 |
| SLC25A3 | -0.0171235 |
| CNEP1R1 | -0.0171365 |
| NLK | -0.0171521 |
| ATP2B1 | -0.0171602 |
| UHRF1BP1L | -0.0171697 |
| CWF19L2 | -0.0171747 |
| DDX55 | -0.0171881 |
| LETM1 | -0.0171904 |
| SLC34A3 | -0.0172078 |
| PBRM1 | -0.0172363 |
| TPPP2 | -0.0172381 |
| DOPEY2 | -0.0172510 |
| CRYBG3 | -0.0172535 |
| RAB3IL1 | -0.0172738 |
| DAG1 | -0.0172806 |
| TP53INP1 | -0.0172951 |
| GABRG2 | -0.0173043 |
| WNK3 | -0.0173230 |
| VRK3 | -0.0173268 |
| PHKB | -0.0173394 |
| KEL | -0.0173416 |
| CCDC172 | -0.0174070 |
| MAK | -0.0174109 |
| MICB | -0.0174222 |
| GPR78 | -0.0174241 |
| SLC17A4 | -0.0174355 |
| SLC6A17 | -0.0174414 |
| HAO1 | -0.0174842 |
| JPH3 | -0.0174886 |
| TEX37 | -0.0174961 |
| PTCD3 | -0.0175017 |
| SPATA8 | -0.0175019 |
| EBAG9 | -0.0175118 |
| ARMC10 | -0.0175402 |
| SPTLC2 | -0.0175620 |
| CEP164 | -0.0175726 |
| MORC3 | -0.0175913 |
| NOC2L | -0.0176239 |
| USP49 | -0.0176333 |
| PNPLA5 | -0.0176472 |
| CPNE6 | -0.0176594 |
| XRCC2 | -0.0176894 |
| FAM69C | -0.0176989 |
| SLC22A14 | -0.0177048 |
| MTIF2 | -0.0177469 |
| AMBN | -0.0177626 |
| SLX1A | -0.0177646 |
| CHRNA1 | -0.0177662 |
| TMEM256 | -0.0177678 |
| OGG1 | -0.0178112 |
| EIF4A3 | -0.0178221 |
| SEP15 | -0.0178266 |
| NAA40 | -0.0178282 |
| MORF4L1 | -0.0178321 |
| YIPF6 | -0.0178363 |
| LOXL2 | -0.0178445 |
| UBIAD1 | -0.0178646 |
| PRR14L | -0.0178654 |
| SPRR2G | -0.0178668 |
| LRRC45 | -0.0178801 |
| SUFU | -0.0178899 |
| HMOX2 | -0.0179008 |
| IPO11 | -0.0179022 |
| LCE4A | -0.0179208 |
| ZBTB14 | -0.0179336 |
| ANAPC11 | -0.0179524 |
| PSMG3 | -0.0179528 |
| PLB1 | -0.0179950 |
| TCP11 | -0.0180327 |
| RAB4A | -0.0180663 |
| KDM4D | -0.0180762 |
| SEC11A | -0.0180804 |
| C12orf56 | -0.0181007 |
| HYAL2 | -0.0181157 |
| NEUROG1 | -0.0181159 |
| TCL1B | -0.0181405 |
| FCHSD1 | -0.0181460 |
| ATP1A4 | -0.0181462 |
| NUP43 | -0.0181671 |
| RPS3 | -0.0181724 |
| BRAF | -0.0181811 |
| TTPA | -0.0181987 |
| CDC14B | -0.0182274 |
| GPR3 | -0.0182658 |
| SLIRP | -0.0183057 |
| CRLS1 | -0.0183090 |
| CHRDL1 | -0.0183135 |
| MC2R | -0.0183153 |
| DNAJC7 | -0.0183163 |
| PTRHD1 | -0.0183400 |
| C17orf100 | -0.0183631 |
| RBFA | -0.0183810 |
| TMEM30A | -0.0184014 |
| GJB4 | -0.0184118 |
| ACYP1 | -0.0184208 |
| LCE2D | -0.0184226 |
| MRPL17 | -0.0184635 |
| PREX2 | -0.0184642 |
| DMPK | -0.0184743 |
| TMEM104 | -0.0184971 |
| OR6Y1 | -0.0185194 |
| CPEB1 | -0.0185262 |
| DNAH17 | -0.0185585 |
| DDX20 | -0.0185612 |
| SSBP3 | -0.0185626 |
| LDLRAD1 | -0.0186212 |
| RAB3D | -0.0186276 |
| PANK4 | -0.0186761 |
| BTNL2 | -0.0186815 |
| GJB6 | -0.0186997 |
| EMILIN3 | -0.0187149 |
| DEFB129 | -0.0187347 |
| NEK3 | -0.0187782 |
| RHOA | -0.0187858 |
| ZFYVE20 | -0.0188052 |
| HSFX1 | -0.0188069 |
| ZFR2 | -0.0188195 |
| MAGEH1 | -0.0188272 |
| CALML4 | -0.0188920 |
| DRD4 | -0.0188993 |
| UBL7 | -0.0189232 |
| CEP95 | -0.0189747 |
| UBE2E1 | -0.0189897 |
| LDLRAP1 | -0.0189899 |
| ATP10D | -0.0190076 |
| GPSM1 | -0.0190276 |
| DGKA | -0.0190412 |
| BROX | -0.0190530 |
| SNAPIN | -0.0190595 |
| POU3F4 | -0.0190666 |
| GHRHR | -0.0190759 |
| PTGS1 | -0.0190771 |
| FAM76B | -0.0190806 |
| WDR45 | -0.0191018 |
| IPCEF1 | -0.0191085 |
| GYPA | -0.0191112 |
| SEPT3 | -0.0191326 |
| AP3M1 | -0.0191336 |
| TRPT1 | -0.0191510 |
| ZFP69B | -0.0191619 |
| ADAM21 | -0.0191994 |
| ABCC1 | -0.0192230 |
| UBQLN1 | -0.0192305 |
| CLASP1 | -0.0192315 |
| EMID1 | -0.0192396 |
| C12orf65 | -0.0192729 |
| SPATA16 | -0.0192743 |
| GPR6 | -0.0192957 |
| P2RY4 | -0.0193081 |
| FFAR3 | -0.0193150 |
| SARDH | -0.0193243 |
| HEPACAM | -0.0193461 |
| C11orf31 | -0.0193485 |
| AKAP1 | -0.0193517 |
| PIGO | -0.0193582 |
| PLCB3 | -0.0193615 |
| USP16 | -0.0193692 |
| MUC19 | -0.0194146 |
| ZNF394 | -0.0194244 |
| C10orf91 | -0.0194253 |
| PRAC1 | -0.0194341 |
| AGRP | -0.0194711 |
| MCU | -0.0194992 |
| ELN | -0.0195018 |
| UFL1 | -0.0195064 |
| EPPIN-WFDC6 | -0.0195400 |
| NUP98 | -0.0195592 |
| HFE | -0.0195827 |
| LRIF1 | -0.0195973 |
| XKR8 | -0.0196307 |
| OR5P2 | -0.0196388 |
| VRTN | -0.0196480 |
| OGDH | -0.0196615 |
| CSPG5 | -0.0196717 |
| CHRM5 | -0.0196883 |
| LHFPL4 | -0.0196964 |
| VAX2 | -0.0197034 |
| LPAR6 | -0.0197176 |
| TMOD1 | -0.0197215 |
| ZZEF1 | -0.0197219 |
| FRMD8 | -0.0197240 |
| CLCC1 | -0.0197362 |
| SEMA7A | -0.0197397 |
| SULT4A1 | -0.0197543 |
| TAF5L | -0.0197648 |
| UBE2V2 | -0.0197671 |
| ACSM2B | -0.0197791 |
| POLR1D | -0.0197805 |
| NIT2 | -0.0197812 |
| PCDHB7 | -0.0198359 |
| ST7 | -0.0198401 |
| CCKAR | -0.0198639 |
| ZNF691 | -0.0198866 |
| TBX18 | -0.0199153 |
| C6orf226 | -0.0199271 |
| TFPT | -0.0199393 |
| RUSC2 | -0.0199453 |
| ASAH2 | -0.0199737 |
| DEFA3 | -0.0199956 |
| LCE2B | -0.0200148 |
| DENND2D | -0.0200219 |
| ZDHHC23 | -0.0200321 |
| GPANK1 | -0.0200592 |
| FAM3A | -0.0200629 |
| CACNG8 | -0.0200686 |
| RRAGA | -0.0200862 |
| TMCO4 | -0.0201012 |
| COMMD6 | -0.0201518 |
| IGSF21 | -0.0201755 |
| PRPF38A | -0.0201786 |
| SLC46A3 | -0.0201807 |
| TNKS2 | -0.0201835 |
| U2SURP | -0.0202145 |
| GOLGA5 | -0.0202209 |
| ST6GALNAC3 | -0.0202307 |
| KHDC1 | -0.0202443 |
| TCTN3 | -0.0202473 |
| RPL26 | -0.0202493 |
| MEIOB | -0.0202638 |
| MLLT10 | -0.0202648 |
| SULT1C4 | -0.0202684 |
| GOLGA3 | -0.0202743 |
| FAM129A | -0.0202795 |
| LY6G6F | -0.0203054 |
| MAGEC1 | -0.0203224 |
| CD160 | -0.0203268 |
| RRS1 | -0.0203684 |
| ACAN | -0.0203696 |
| SLC22A17 | -0.0203698 |
| RPS11 | -0.0203977 |
| DCLK2 | -0.0204037 |
| GLCCI1 | -0.0204290 |
| TSKS | -0.0204845 |
| CINP | -0.0205408 |
| UBE2D3 | -0.0205531 |
| DPYSL4 | -0.0205576 |
| PELO | -0.0205759 |
| BCAP31 | -0.0205864 |
| CPT2 | -0.0205869 |
| DUSP8 | -0.0205982 |
| MTRF1L | -0.0206001 |
| RPL17 | -0.0206064 |
| TRIM65 | -0.0206080 |
| ZNF454 | -0.0206265 |
| RAB4B | -0.0206341 |
| ZDHHC8 | -0.0206495 |
| SHMT1 | -0.0206940 |
| C7orf34 | -0.0206952 |
| KCTD17 | -0.0206983 |
| ABCA4 | -0.0207174 |
| TBXA2R | -0.0207461 |
| SLC12A3 | -0.0207556 |
| TIMM9 | -0.0207591 |
| CLSTN1 | -0.0208077 |
| MS4A12 | -0.0208131 |
| TRIM28 | -0.0208143 |
| SAP130 | -0.0208277 |
| PDC | -0.0208433 |
| HPRT1 | -0.0208559 |
| PTPRZ1 | -0.0208705 |
| HIST1H2BN | -0.0208941 |
| SLC23A3 | -0.0209054 |
| ASPSCR1 | -0.0209096 |
| ZNF121 | -0.0209255 |
| SPCS2 | -0.0209342 |
| AGO3 | -0.0209432 |
| FBXO31 | -0.0209610 |
| POU6F2 | -0.0209842 |
| DHODH | -0.0209939 |
| GKN1 | -0.0209989 |
| UBXN7 | -0.0210095 |
| RPLP2 | -0.0210123 |
| CD1D | -0.0210368 |
| HSPB6 | -0.0210589 |
| TCF4 | -0.0210694 |
| UTS2B | -0.0210886 |
| KDELC2 | -0.0210893 |
| RAP1GAP2 | -0.0210931 |
| ADAMTS1 | -0.0211011 |
| SQSTM1 | -0.0211060 |
| SYNDIG1L | -0.0211066 |
| TPST1 | -0.0211169 |
| TM9SF3 | -0.0211246 |
| COX7A2L | -0.0211433 |
| PRKRIP1 | -0.0211526 |
| CXCL12 | -0.0211633 |
| PLXND1 | -0.0211698 |
| ACAD8 | -0.0211782 |
| DNTTIP2 | -0.0211824 |
| ZNF277 | -0.0212103 |
| PIAS4 | -0.0212155 |
| LMX1A | -0.0212211 |
| CYP3A43 | -0.0212301 |
| SLK | -0.0212420 |
| ESM1 | -0.0212507 |
| TM6SF2 | -0.0212859 |
| FOXL2 | -0.0212947 |
| FAM9B | -0.0213028 |
| PCDHB10 | -0.0213383 |
| KRTAP13-2 | -0.0213413 |
| NBN | -0.0213426 |
| SLC22A1 | -0.0213559 |
| SART3 | -0.0213572 |
| URM1 | -0.0213836 |
| MUC2 | -0.0213902 |
| KIRREL | -0.0213921 |
| COPS6 | -0.0214317 |
| PRDM15 | -0.0214381 |
| TRIM11 | -0.0214780 |
| CGNL1 | -0.0214859 |
| OR13C4 | -0.0215146 |
| SLC22A12 | -0.0215298 |
| GSX1 | -0.0215327 |
| ATOH7 | -0.0215337 |
| CALY | -0.0215694 |
| IL17F | -0.0215717 |
| SLC35A4 | -0.0215808 |
| BCL7B | -0.0216078 |
| HSPB9 | -0.0216155 |
| VWA5B2 | -0.0216262 |
| HAUS1 | -0.0216277 |
| ADM5 | -0.0216288 |
| C6orf223 | -0.0216288 |
| UPB1 | -0.0216882 |
| NMUR1 | -0.0216949 |
| ZPBP | -0.0216983 |
| EPAS1 | -0.0217064 |
| LARP1 | -0.0217203 |
| C16orf59 | -0.0217217 |
| CDKN2B | -0.0217273 |
| SLC25A6 | -0.0217319 |
| ZNF506 | -0.0217479 |
| SLC19A3 | -0.0217525 |
| YPEL5 | -0.0217597 |
| SYCP2L | -0.0218006 |
| TNFSF11 | -0.0218069 |
| BRS3 | -0.0218127 |
| AIP | -0.0218142 |
| SGK223 | -0.0218197 |
| HERC4 | -0.0218349 |
| SFTPC | -0.0218398 |
| PLEKHG5 | -0.0218595 |
| FKBP14 | -0.0218947 |
| LINC00999 | -0.0219040 |
| RILPL2 | -0.0219044 |
| FOCAD | -0.0219514 |
| CRKL | -0.0219528 |
| STRIP1 | -0.0219578 |
| TIGD3 | -0.0219599 |
| HIST1H3D | -0.0219615 |
| MRE11A | -0.0219731 |
| UBQLN2 | -0.0219734 |
| SLC25A43 | -0.0219983 |
| C8orf22 | -0.0219997 |
| ENTPD6 | -0.0220311 |
| MLANA | -0.0220341 |
| RPL15 | -0.0220358 |
| LYST | -0.0220375 |
| MAGOHB | -0.0220393 |
| PTCH1 | -0.0220500 |
| DLEU7 | -0.0220856 |
| ARGLU1 | -0.0220879 |
| ZIK1 | -0.0221273 |
| RIMS3 | -0.0222126 |
| SULT2A1 | -0.0222134 |
| PPM1B | -0.0222162 |
| JMY | -0.0222371 |
| DHX33 | -0.0222450 |
| GPLD1 | -0.0222494 |
| GPR35 | -0.0222559 |
| LCN15 | -0.0222865 |
| LYPD2 | -0.0222949 |
| KRTAP19-1 | -0.0223000 |
| SRSF10 | -0.0223039 |
| ENDOU | -0.0223044 |
| RPS28 | -0.0223100 |
| RNF4 | -0.0223187 |
| KLHL29 | -0.0223431 |
| INSM2 | -0.0223497 |
| C1orf204 | -0.0223599 |
| BCR | -0.0223824 |
| AFAP1L1 | -0.0223838 |
| SON | -0.0223898 |
| MOB4 | -0.0224006 |
| PRICKLE3 | -0.0224122 |
| MLIP | -0.0224174 |
| HBZ | -0.0224216 |
| PRR5-ARHGAP8 | -0.0224240 |
| FAM122C | -0.0224387 |
| AUTS2 | -0.0224404 |
| MKRN1 | -0.0224513 |
| ZNF35 | -0.0224565 |
| TNFRSF10B | -0.0224814 |
| SCG5 | -0.0224818 |
| VPS26B | -0.0224908 |
| GLP2R | -0.0224929 |
| OTC | -0.0225082 |
| DIS3L2 | -0.0225361 |
| DBH | -0.0225431 |
| C18orf25 | -0.0225484 |
| TDRP | -0.0225568 |
| MTFMT | -0.0225702 |
| SEMA6B | -0.0225774 |
| LONP1 | -0.0225934 |
| SNX29 | -0.0226192 |
| EPPK1 | -0.0226319 |
| C21orf33 | -0.0226371 |
| KIAA0355 | -0.0226780 |
| AGPAT5 | -0.0226891 |
| PHTF2 | -0.0226965 |
| AKR1C1 | -0.0227046 |
| NACA | -0.0227207 |
| DAPK3 | -0.0227289 |
| SYPL1 | -0.0227403 |
| TLCD2 | -0.0227514 |
| CLDN2 | -0.0227570 |
| NSD1 | -0.0228014 |
| CNOT6L | -0.0228211 |
| TMPRSS11E | -0.0228535 |
| C9orf16 | -0.0228773 |
| KLHL18 | -0.0229251 |
| CD63 | -0.0229290 |
| GLYCTK | -0.0229499 |
| TPM2 | -0.0229507 |
| MRPL41 | -0.0229574 |
| BARHL1 | -0.0229581 |
| USF2 | -0.0229963 |
| CDS2 | -0.0230112 |
| MCAM | -0.0230339 |
| TPO | -0.0230343 |
| AGAP3 | -0.0230372 |
| EDAR | -0.0230521 |
| CYP1A2 | -0.0230643 |
| DOLPP1 | -0.0230683 |
| C15orf41 | -0.0230765 |
| SOX18 | -0.0231002 |
| PRB1 | -0.0231384 |
| DPPA2 | -0.0231391 |
| MYO1D | -0.0231391 |
| TAS2R13 | -0.0231463 |
| GDF3 | -0.0231485 |
| TIA1 | -0.0231607 |
| TET3 | -0.0231648 |
| PARPBP | -0.0231945 |
| PANK1 | -0.0231973 |
| N4BP2L2 | -0.0232071 |
| FUT10 | -0.0232132 |
| C11orf57 | -0.0232160 |
| FAM187B | -0.0232249 |
| SLAMF9 | -0.0232285 |
| MVB12A | -0.0232494 |
| TERF2IP | -0.0232872 |
| CTU1 | -0.0232957 |
| FOXD3 | -0.0233244 |
| ITM2B | -0.0233273 |
| ANKRD7 | -0.0233303 |
| UBE2Q2 | -0.0233398 |
| T | -0.0233569 |
| MYL6 | -0.0233608 |
| NHEJ1 | -0.0233738 |
| PPM1K | -0.0233787 |
| APOO | -0.0233921 |
| DCX | -0.0234088 |
| PPAPDC1A | -0.0234114 |
| TCTE1 | -0.0234436 |
| MID2 | -0.0234467 |
| ATXN7L3 | -0.0234518 |
| TUBB8 | -0.0234664 |
| C19orf60 | -0.0234674 |
| ZBTB9 | -0.0234698 |
| TRIM68 | -0.0234902 |
| MAP7 | -0.0235061 |
| OR8D1 | -0.0235093 |
| HKDC1 | -0.0235194 |
| MAPK10 | -0.0235430 |
| RPS6KB1 | -0.0235465 |
| CPSF4 | -0.0235550 |
| SMARCAL1 | -0.0235674 |
| CNIH2 | -0.0235849 |
| SLC4A5 | -0.0235912 |
| SLC44A5 | -0.0236332 |
| FLT4 | -0.0236403 |
| EPM2A | -0.0236511 |
| TAOK2 | -0.0236879 |
| EPC1 | -0.0237234 |
| NRG1 | -0.0237335 |
| PHF1 | -0.0237559 |
| WDPCP | -0.0237703 |
| SLCO1B3 | -0.0238059 |
| DHRS7C | -0.0238102 |
| OPRL1 | -0.0238133 |
| RPAP3 | -0.0238681 |
| RBM48 | -0.0238884 |
| COL20A1 | -0.0239043 |
| BANP | -0.0239049 |
| LDB1 | -0.0239175 |
| TGIF2 | -0.0239224 |
| CPLX3 | -0.0239253 |
| TGIF1 | -0.0239272 |
| GPKOW | -0.0239291 |
| COPRS | -0.0239486 |
| NPY | -0.0239536 |
| RAB5C | -0.0239708 |
| AQP12B | -0.0239830 |
| NEK8 | -0.0239974 |
| FAM160A1 | -0.0240002 |
| STK31 | -0.0240046 |
| IL1RL2 | -0.0240238 |
| PRM3 | -0.0240460 |
| TMEM126B | -0.0240498 |
| TXNDC2 | -0.0240507 |
| NEU2 | -0.0240569 |
| KCNC4 | -0.0240709 |
| SH3PXD2B | -0.0240817 |
| CCDC92 | -0.0240877 |
| CLEC4F | -0.0240893 |
| OR5I1 | -0.0240990 |
| TM4SF18 | -0.0241154 |
| LEPROT | -0.0241206 |
| NR1D1 | -0.0241377 |
| RMND5A | -0.0241571 |
| CNOT10 | -0.0241618 |
| TMEM127 | -0.0241783 |
| RAB2A | -0.0241832 |
| RBM33 | -0.0241852 |
| NOG | -0.0241861 |
| SHISA9 | -0.0241965 |
| TTN | -0.0241992 |
| FLT1 | -0.0242030 |
| OR7A10 | -0.0242074 |
| BLOC1S2 | -0.0242106 |
| LHFPL1 | -0.0242110 |
| DOCK7 | -0.0242135 |
| ARHGEF10L | -0.0242186 |
| TTI1 | -0.0242307 |
| GABRB2 | -0.0242310 |
| B3GNT6 | -0.0242554 |
| SERP1 | -0.0242777 |
| KMT2A | -0.0242793 |
| B3GALT4 | -0.0242885 |
| MCAT | -0.0242930 |
| RPL37 | -0.0243028 |
| BOLA2B | -0.0243063 |
| MAP3K2 | -0.0243093 |
| TCAIM | -0.0243121 |
| ODF4 | -0.0243206 |
| EXOSC10 | -0.0243504 |
| DAGLB | -0.0243508 |
| CPLX2 | -0.0243574 |
| HMGCR | -0.0243709 |
| DOCK4 | -0.0243792 |
| POLH | -0.0243890 |
| CADM3 | -0.0243891 |
| RBM15B | -0.0244003 |
| C20orf197 | -0.0244175 |
| BIVM | -0.0244264 |
| SGSH | -0.0244440 |
| NUCB1 | -0.0244455 |
| MCOLN1 | -0.0244617 |
| LRTM1 | -0.0244783 |
| OPRD1 | -0.0244857 |
| JUND | -0.0244870 |
| RPS3A | -0.0245357 |
| PCOLCE2 | -0.0245476 |
| DGCR2 | -0.0245522 |
| PALD1 | -0.0245595 |
| BCMO1 | -0.0245693 |
| USP31 | -0.0245736 |
| RSPH6A | -0.0245855 |
| THAP7 | -0.0245880 |
| POLR2K | -0.0246057 |
| EIF4E3 | -0.0246292 |
| CRYAA | -0.0246304 |
| RUFY3 | -0.0246428 |
| EXOSC3 | -0.0246670 |
| C16orf78 | -0.0246743 |
| PGLS | -0.0246773 |
| FRS3 | -0.0247122 |
| RRM1 | -0.0247174 |
| KMT2C | -0.0247238 |
| NUP107 | -0.0247263 |
| OS9 | -0.0247268 |
| HARS | -0.0247725 |
| CASS4 | -0.0247817 |
| TNFSF8 | -0.0247885 |
| SPRTN | -0.0247909 |
| SEPT14 | -0.0247920 |
| TRIP11 | -0.0247920 |
| NIN | -0.0247978 |
| KIAA1919 | -0.0248035 |
| ZNF529 | -0.0248101 |
| FGF6 | -0.0248125 |
| DNTTIP1 | -0.0248229 |
| ACAP2 | -0.0248238 |
| P2RX2 | -0.0248392 |
| VAMP3 | -0.0248410 |
| ZNF512B | -0.0248501 |
| KRT33B | -0.0248610 |
| DRD3 | -0.0248865 |
| EGFLAM | -0.0249013 |
| C14orf119 | -0.0249036 |
| TCF7L2 | -0.0249217 |
| FAM104B | -0.0249264 |
| ABCA7 | -0.0249580 |
| TNK2 | -0.0249633 |
| APOPT1 | -0.0249872 |
| HACL1 | -0.0249949 |
| BRCC3 | -0.0250227 |
| GOLGA6L2 | -0.0250320 |
| ATP6AP2 | -0.0250477 |
| DHX57 | -0.0250488 |
| CDPF1 | -0.0250518 |
| WNT10B | -0.0250546 |
| MRGPRX4 | -0.0250622 |
| TBRG1 | -0.0250791 |
| ENTPD4 | -0.0250950 |
| ZNF467 | -0.0251090 |
| C3orf33 | -0.0251168 |
| TARDBP | -0.0251182 |
| PYGM | -0.0251190 |
| ACBD7 | -0.0251193 |
| LAMC3 | -0.0251328 |
| SYT14 | -0.0251605 |
| GNAI3 | -0.0251744 |
| KISS1 | -0.0251815 |
| ZRANB2 | -0.0251972 |
| EIF2B2 | -0.0251981 |
| CLDN15 | -0.0252111 |
| CDC42EP3 | -0.0252290 |
| BRD4 | -0.0252364 |
| FGA | -0.0252421 |
| HS1BP3 | -0.0252427 |
| PAGE2B | -0.0252513 |
| SARNP | -0.0252520 |
| RTTN | -0.0252807 |
| PRKCG | -0.0252951 |
| OR10C1 | -0.0252964 |
| NUDT11 | -0.0253022 |
| APLF | -0.0253070 |
| SV2C | -0.0253235 |
| KRTAP9-9 | -0.0253417 |
| GRIN1 | -0.0253505 |
| FGF1 | -0.0253654 |
| C7orf10 | -0.0254180 |
| SEPT9 | -0.0254189 |
| COL12A1 | -0.0254362 |
| SPDYE4 | -0.0254363 |
| TGS1 | -0.0254682 |
| SLC36A3 | -0.0254720 |
| ZNF317 | -0.0254844 |
| TBP | -0.0255043 |
| TDRD10 | -0.0255095 |
| ATG9B | -0.0255644 |
| RUVBL2 | -0.0255669 |
| RPL30 | -0.0255709 |
| MUC5B | -0.0255766 |
| SLC6A7 | -0.0255968 |
| FGF21 | -0.0256267 |
| TDP2 | -0.0256281 |
| PRDM16 | -0.0256458 |
| HSPBP1 | -0.0256684 |
| WIF1 | -0.0256810 |
| KRTAP15-1 | -0.0256851 |
| PAX5 | -0.0256924 |
| OSBPL2 | -0.0257127 |
| EFCAB12 | -0.0257132 |
| DPF1 | -0.0257570 |
| ADRB3 | -0.0257660 |
| TMEM98 | -0.0257726 |
| PTCD1 | -0.0257896 |
| CEP350 | -0.0257917 |
| EXOSC6 | -0.0258144 |
| XPNPEP3 | -0.0258299 |
| TMEM200C | -0.0258325 |
| NOS1 | -0.0258329 |
| SFXN1 | -0.0258366 |
| KIAA1755 | -0.0258398 |
| HAVCR1 | -0.0258481 |
| SELM | -0.0258491 |
| EIF1 | -0.0258606 |
| REV3L | -0.0258640 |
| TRA2A | -0.0258685 |
| PA2G4 | -0.0258869 |
| RAB2B | -0.0258947 |
| AVP | -0.0259221 |
| OTP | -0.0259273 |
| TIMM21 | -0.0259313 |
| TMEM182 | -0.0259585 |
| ZKSCAN7 | -0.0259630 |
| PTPN11 | -0.0259746 |
| ARAP1 | -0.0259929 |
| TIMM17A | -0.0260237 |
| RANBP2 | -0.0260307 |
| HDAC9 | -0.0261027 |
| COG8 | -0.0261192 |
| COPS7B | -0.0261222 |
| FGD1 | -0.0261234 |
| BIN3 | -0.0261269 |
| ZNF185 | -0.0261313 |
| FPGS | -0.0261483 |
| PALM2 | -0.0261581 |
| ZRSR2 | -0.0261636 |
| EXOC5 | -0.0261853 |
| RDH13 | -0.0262037 |
| ADNP2 | -0.0262119 |
| TMEM223 | -0.0262311 |
| PIK3R4 | -0.0262420 |
| CDH7 | -0.0262552 |
| EIF1AY | -0.0262594 |
| QTRTD1 | -0.0262711 |
| ATAT1 | -0.0263435 |
| RBM41 | -0.0263786 |
| RP9 | -0.0263807 |
| GGT6 | -0.0263826 |
| DYRK1A | -0.0263989 |
| SYDE1 | -0.0264185 |
| UNC45B | -0.0264227 |
| FBXO34 | -0.0264302 |
| GUCY1B3 | -0.0264388 |
| ANKRD34B | -0.0264431 |
| OR52B2 | -0.0264566 |
| EPS15 | -0.0264748 |
| NAT9 | -0.0264890 |
| CCBE1 | -0.0265007 |
| DENND5B | -0.0265201 |
| TTLL7 | -0.0265549 |
| SLC35B4 | -0.0265614 |
| SCML2 | -0.0265716 |
| CHSY1 | -0.0265932 |
| ARMCX6 | -0.0265948 |
| TRIT1 | -0.0266157 |
| LRIG2 | -0.0266182 |
| TVP23B | -0.0266435 |
| ZSCAN25 | -0.0266583 |
| FUNDC2 | -0.0266706 |
| CMC1 | -0.0266731 |
| ATL1 | -0.0266764 |
| CMIP | -0.0266909 |
| BTAF1 | -0.0266937 |
| C1orf43 | -0.0267030 |
| MAMSTR | -0.0267378 |
| DLX6 | -0.0267838 |
| PLVAP | -0.0267982 |
| ALX3 | -0.0268000 |
| CCDC144A | -0.0268196 |
| TNR | -0.0268200 |
| RDH8 | -0.0268283 |
| MFSD11 | -0.0268961 |
| RAB9B | -0.0269406 |
| GPRC5D | -0.0269718 |
| OR3A2 | -0.0269784 |
| ARHGEF6 | -0.0269960 |
| RASGEF1C | -0.0270060 |
| APOA5 | -0.0270259 |
| JAK1 | -0.0270402 |
| MEPCE | -0.0270440 |
| MEGF6 | -0.0270865 |
| IMMP1L | -0.0271187 |
| TAS2R43 | -0.0271202 |
| CRYBA4 | -0.0271228 |
| SPATA12 | -0.0271280 |
| TMEM185B | -0.0271589 |
| LRCH3 | -0.0271603 |
| KIAA1731 | -0.0271694 |
| SNRPB2 | -0.0271833 |
| CLDN9 | -0.0272061 |
| APBA3 | -0.0272185 |
| RPS6KA2 | -0.0272327 |
| ZBTB22 | -0.0272478 |
| TBRG4 | -0.0272515 |
| TM9SF1 | -0.0272604 |
| SETD4 | -0.0272910 |
| VHL | -0.0272921 |
| VPS33B | -0.0272959 |
| DES | -0.0273149 |
| CSNK2A1 | -0.0273763 |
| ZNF652 | -0.0273791 |
| FAM208B | -0.0274234 |
| ATG9A | -0.0274493 |
| OR2B2 | -0.0274504 |
| ITGB1BP1 | -0.0274513 |
| TP53TG3 | -0.0274597 |
| TGIF2LY | -0.0274837 |
| FGF9 | -0.0274938 |
| KRTAP3-2 | -0.0275083 |
| DDHD1 | -0.0275365 |
| BMPR1A | -0.0275427 |
| UBXN4 | -0.0275612 |
| HADH | -0.0275619 |
| HHLA1 | -0.0275709 |
| TMEM252 | -0.0275883 |
| RAB6A | -0.0275943 |
| COIL | -0.0275972 |
| RPP30 | -0.0276302 |
| HIST1H4H | -0.0276310 |
| PTBP2 | -0.0276505 |
| NIPSNAP3B | -0.0276616 |
| FMNL3 | -0.0276682 |
| PLA2G3 | -0.0276687 |
| POMT1 | -0.0276734 |
| SP8 | -0.0276738 |
| LIX1 | -0.0276784 |
| GABARAPL1 | -0.0276856 |
| LPP | -0.0276957 |
| FBRS | -0.0276992 |
| MTSS1 | -0.0277216 |
| LRFN1 | -0.0277293 |
| ZNF79 | -0.0277321 |
| FGF2 | -0.0277368 |
| PRY2 | -0.0277557 |
| NUTM2D | -0.0277634 |
| ZNF257 | -0.0277843 |
| PFN3 | -0.0277915 |
| EYA2 | -0.0277928 |
| IL17RD | -0.0277936 |
| STRN | -0.0278228 |
| TIMM17B | -0.0278523 |
| ANKHD1 | -0.0278601 |
| CALM2 | -0.0278788 |
| C14orf159 | -0.0278845 |
| FAM218A | -0.0279040 |
| LIM2 | -0.0279128 |
| DBF4B | -0.0279151 |
| BCAS2 | -0.0279380 |
| IL11RA | -0.0279404 |
| CSHL1 | -0.0279466 |
| RAB40AL | -0.0279482 |
| TMEM18 | -0.0279659 |
| TUSC1 | -0.0279847 |
| FHIT | -0.0279875 |
| PARP10 | -0.0280202 |
| CPED1 | -0.0280248 |
| ZNF335 | -0.0280362 |
| PNPLA6 | -0.0280437 |
| OR51A7 | -0.0280586 |
| FANCD2OS | -0.0280716 |
| MYL9 | -0.0280803 |
| DDX3X | -0.0280975 |
| RPS6KC1 | -0.0281152 |
| PFDN4 | -0.0281161 |
| ITGA2B | -0.0281264 |
| PLXNA2 | -0.0281356 |
| DRAXIN | -0.0281569 |
| PPCDC | -0.0281641 |
| HIST1H3H | -0.0281679 |
| DICER1 | -0.0281741 |
| ZNF575 | -0.0281828 |
| NOM1 | -0.0281885 |
| RREB1 | -0.0281917 |
| ALDH3B2 | -0.0281981 |
| SELP | -0.0281995 |
| OR4S1 | -0.0282077 |
| SNAP91 | -0.0282130 |
| MTRF1 | -0.0282188 |
| FGL1 | -0.0282221 |
| PAPOLG | -0.0282313 |
| ZNF445 | -0.0282597 |
| INTS5 | -0.0282753 |
| CATSPER4 | -0.0282764 |
| SYN3 | -0.0282808 |
| NCOA4 | -0.0282968 |
| ALDH3A1 | -0.0283344 |
| FAM8A1 | -0.0283378 |
| TUBGCP2 | -0.0283607 |
| UPRT | -0.0283679 |
| PPARGC1A | -0.0283902 |
| HNRNPC | -0.0283963 |
| CNTFR | -0.0283998 |
| LCN8 | -0.0284099 |
| ANKRD10 | -0.0284200 |
| ITFG1 | -0.0284477 |
| ASTE1 | -0.0284530 |
| DLG3 | -0.0284608 |
| MAGEA1 | -0.0284648 |
| PPAPDC3 | -0.0284706 |
| ZMYM5 | -0.0284785 |
| PPP2R4 | -0.0284956 |
| METTL1 | -0.0285118 |
| ACBD3 | -0.0285501 |
| GPR173 | -0.0285637 |
| PCDHGC4 | -0.0285672 |
| CHMP2B | -0.0285713 |
| SCN1A | -0.0285714 |
| CLDN8 | -0.0285760 |
| BFAR | -0.0286014 |
| C7orf60 | -0.0286077 |
| TMCO3 | -0.0286103 |
| IFITM3 | -0.0286218 |
| CFTR | -0.0286246 |
| DNAJC5G | -0.0286300 |
| HCAR2 | -0.0286361 |
| CPA2 | -0.0286487 |
| WDSUB1 | -0.0286516 |
| ARHGEF38 | -0.0286571 |
| CARD14 | -0.0286594 |
| MTMR4 | -0.0286623 |
| OLAH | -0.0286745 |
| METTL3 | -0.0286758 |
| SORBS3 | -0.0286866 |
| AP3B1 | -0.0287141 |
| SKI | -0.0287393 |
| UBN1 | -0.0287513 |
| KLHL22 | -0.0287515 |
| WDR18 | -0.0287611 |
| SRPX | -0.0287622 |
| JMJD1C | -0.0287638 |
| TACSTD2 | -0.0287651 |
| TSPAN15 | -0.0287718 |
| HMG20A | -0.0287821 |
| UBE2R2 | -0.0287988 |
| CA1 | -0.0288022 |
| APAF1 | -0.0288070 |
| SMARCA5 | -0.0288082 |
| IL22RA1 | -0.0288198 |
| ADD2 | -0.0288253 |
| HOXB7 | -0.0288663 |
| SLC5A5 | -0.0288669 |
| HNF1B | -0.0289065 |
| NPBWR2 | -0.0289182 |
| ACVR1 | -0.0289193 |
| PPP2R5E | -0.0289226 |
| PAX4 | -0.0289261 |
| ARHGAP28 | -0.0289278 |
| KLHL32 | -0.0289476 |
| TGFBRAP1 | -0.0289490 |
| ZNF143 | -0.0289492 |
| MED17 | -0.0289578 |
| CAPZA2 | -0.0289986 |
| KRTAP9-8 | -0.0290109 |
| MRPS23 | -0.0290125 |
| SSTR4 | -0.0290185 |
| CCNF | -0.0290894 |
| ACSS3 | -0.0291126 |
| RFESD | -0.0291588 |
| CRNKL1 | -0.0291600 |
| RPL34 | -0.0291768 |
| NR3C1 | -0.0291835 |
| TMEM237 | -0.0291922 |
| WDR41 | -0.0291925 |
| YRDC | -0.0292091 |
| FFAR1 | -0.0292127 |
| DRG2 | -0.0292281 |
| HK2 | -0.0292497 |
| CDHR1 | -0.0292791 |
| SMARCAD1 | -0.0292799 |
| GUCY2F | -0.0293085 |
| CAMK2A | -0.0293103 |
| RYK | -0.0293368 |
| MAPKAPK2 | -0.0293417 |
| ACPP | -0.0293555 |
| PRR24 | -0.0293618 |
| CHST7 | -0.0293643 |
| GABRR1 | -0.0293766 |
| TREX1 | -0.0293890 |
| SLC10A7 | -0.0294100 |
| TMIE | -0.0294563 |
| ELK4 | -0.0294591 |
| GUCA1B | -0.0294649 |
| GPRIN3 | -0.0294899 |
| HOOK3 | -0.0294903 |
| HBP1 | -0.0295165 |
| RNF32 | -0.0295239 |
| KDM4C | -0.0295262 |
| AP5Z1 | -0.0295539 |
| KIAA1715 | -0.0295606 |
| CTNNAL1 | -0.0295996 |
| ZNF544 | -0.0296290 |
| C2orf66 | -0.0296372 |
| RBBP4 | -0.0296400 |
| CPNE1 | -0.0296405 |
| SMG6 | -0.0296424 |
| CAPN10 | -0.0296911 |
| MRPL46 | -0.0296967 |
| FRRS1L | -0.0296969 |
| HOXD11 | -0.0297632 |
| EEFSEC | -0.0297860 |
| NUPL2 | -0.0297907 |
| MOBP | -0.0298005 |
| OSGIN1 | -0.0298065 |
| SEPT2 | -0.0298133 |
| ZNF283 | -0.0298538 |
| ZNF367 | -0.0298573 |
| ESYT2 | -0.0298587 |
| IQCF2 | -0.0298636 |
| HSPH1 | -0.0298638 |
| MRPL49 | -0.0298646 |
| FRRS1 | -0.0298867 |
| SERPINF2 | -0.0298899 |
| KPNA5 | -0.0298921 |
| GLB1L2 | -0.0299113 |
| HDLBP | -0.0299343 |
| ACTRT1 | -0.0299359 |
| ZNF778 | -0.0299602 |
| HAS1 | -0.0299670 |
| MPV17 | -0.0299717 |
| GTSF1L | -0.0299771 |
| PGLYRP3 | -0.0299850 |
| ODF3 | -0.0300086 |
| SLC4A1 | -0.0300138 |
| LPCAT4 | -0.0300156 |
| IQCF1 | -0.0300241 |
| NIF3L1 | -0.0300329 |
| RPL27A | -0.0300833 |
| GPR115 | -0.0300865 |
| SLC18A3 | -0.0301321 |
| COL15A1 | -0.0301353 |
| CEACAM5 | -0.0301522 |
| RNF150 | -0.0301588 |
| RALB | -0.0301716 |
| EMC10 | -0.0301771 |
| KIAA1875 | -0.0302001 |
| KSR1 | -0.0302051 |
| NOL9 | -0.0302165 |
| STK38L | -0.0302249 |
| SPATA25 | -0.0302360 |
| CD300E | -0.0302377 |
| ZNF341 | -0.0302413 |
| KLHDC8A | -0.0302431 |
| ZBTB38 | -0.0302545 |
| SSTR5 | -0.0302646 |
| KPNB1 | -0.0302807 |
| TRIM72 | -0.0303301 |
| SASS6 | -0.0303662 |
| CYSLTR2 | -0.0303747 |
| SMAD6 | -0.0303879 |
| CA7 | -0.0303962 |
| ARX | -0.0304090 |
| C6orf100 | -0.0304192 |
| TMEM56 | -0.0304245 |
| SH3GL1 | -0.0304317 |
| SGTA | -0.0305003 |
| DNAH1 | -0.0305268 |
| ANO6 | -0.0305287 |
| CCDC67 | -0.0305319 |
| HTR1A | -0.0305735 |
| RHBDL3 | -0.0305753 |
| ZNF451 | -0.0305767 |
| ZSWIM3 | -0.0305881 |
| GH1 | -0.0305919 |
| USP54 | -0.0306103 |
| EVC2 | -0.0306139 |
| ALDOC | -0.0306156 |
| SLIT3 | -0.0306423 |
| TMSB4Y | -0.0306485 |
| PLD4 | -0.0306580 |
| LRRC16A | -0.0306909 |
| MNT | -0.0307298 |
| YIPF4 | -0.0307339 |
| FAM24B | -0.0307361 |
| MAP4K4 | -0.0307391 |
| GPHA2 | -0.0307422 |
| CRYGD | -0.0307580 |
| FBXL3 | -0.0307622 |
| NR1I3 | -0.0307790 |
| CTAGE1 | -0.0307835 |
| FAF2 | -0.0307920 |
| BCLAF1 | -0.0308182 |
| KLHL4 | -0.0308232 |
| CLASRP | -0.0308288 |
| TACC1 | -0.0308412 |
| CNR1 | -0.0308421 |
| PIAS2 | -0.0308614 |
| SERPINB2 | -0.0308741 |
| ANKRD16 | -0.0308803 |
| ERAP1 | -0.0308864 |
| PPP1R17 | -0.0308904 |
| ZNF491 | -0.0309055 |
| BTBD6 | -0.0309111 |
| CAPN1 | -0.0309180 |
| IL36G | -0.0309192 |
| DPP6 | -0.0309654 |
| AKAP3 | -0.0309781 |
| FREM3 | -0.0309847 |
| C17orf78 | -0.0309943 |
| GID4 | -0.0309945 |
| MROH6 | -0.0310110 |
| GPATCH3 | -0.0310202 |
| TPT1 | -0.0310374 |
| SNAPC1 | -0.0310473 |
| PDGFB | -0.0310769 |
| GRSF1 | -0.0310804 |
| RPL11 | -0.0310860 |
| CDK14 | -0.0310875 |
| XYLB | -0.0310944 |
| WWP2 | -0.0310958 |
| SERTAD1 | -0.0311176 |
| ANAPC1 | -0.0311213 |
| SHH | -0.0311278 |
| ITPKC | -0.0311305 |
| LRFN3 | -0.0311309 |
| TAAR8 | -0.0311351 |
| C12orf52 | -0.0311825 |
| CEP41 | -0.0311828 |
| RPL13 | -0.0312024 |
| CNTNAP1 | -0.0312220 |
| TP63 | -0.0312257 |
| SLC22A6 | -0.0312262 |
| DUSP7 | -0.0312285 |
| TP53I11 | -0.0312495 |
| MRPS24 | -0.0312650 |
| ENPP6 | -0.0312844 |
| PDE4D | -0.0312863 |
| HOXA5 | -0.0312934 |
| SLC25A39 | -0.0313067 |
| WAPAL | -0.0313164 |
| ANKRD53 | -0.0313208 |
| PDIA3 | -0.0313437 |
| KIAA1147 | -0.0313680 |
| TBL1X | -0.0313782 |
| OR4D5 | -0.0313863 |
| HRH3 | -0.0314081 |
| FRG1B | -0.0314113 |
| DNAJB6 | -0.0314120 |
| ZNF565 | -0.0314130 |
| KIF21A | -0.0314173 |
| HFE2 | -0.0314191 |
| TRAPPC2L | -0.0314302 |
| KCNN1 | -0.0314734 |
| SLC6A8 | -0.0314753 |
| SNCB | -0.0314765 |
| THOC7 | -0.0315001 |
| SLC10A4 | -0.0315126 |
| MAGEE2 | -0.0315222 |
| CNBP | -0.0315309 |
| C19orf40 | -0.0315335 |
| RALGAPA2 | -0.0315343 |
| THPO | -0.0315410 |
| FASTKD1 | -0.0315502 |
| PEX10 | -0.0315700 |
| DLGAP4 | -0.0315733 |
| GAA | -0.0315773 |
| RNF31 | -0.0315784 |
| UHMK1 | -0.0315940 |
| COPA | -0.0316332 |
| PPP1R21 | -0.0316352 |
| FAM133A | -0.0316503 |
| NR2C1 | -0.0316767 |
| LCE3C | -0.0316784 |
| TRIM74 | -0.0316821 |
| GPR107 | -0.0316878 |
| CLDN3 | -0.0316983 |
| AMBP | -0.0317045 |
| C1orf131 | -0.0317082 |
| KRTAP17-1 | -0.0317364 |
| VPS26A | -0.0317393 |
| SLC6A11 | -0.0317506 |
| CSN2 | -0.0317556 |
| VWA5A | -0.0318135 |
| SMAD9 | -0.0318213 |
| ARHGDIA | -0.0318312 |
| FAM9A | -0.0318578 |
| SP3 | -0.0318580 |
| TRIM34 | -0.0318925 |
| CPXCR1 | -0.0318951 |
| B3GALNT1 | -0.0319063 |
| ITGAD | -0.0319082 |
| B3GALTL | -0.0319354 |
| AGER | -0.0319403 |
| BRAP | -0.0319525 |
| HIPK2 | -0.0319701 |
| ZNF461 | -0.0319740 |
| GIPC3 | -0.0319842 |
| TAX1BP1 | -0.0319986 |
| UNC119 | -0.0320080 |
| RBM19 | -0.0320111 |
| FAM209A | -0.0320374 |
| IGSF11 | -0.0320423 |
| SWT1 | -0.0320446 |
| PTGFRN | -0.0320477 |
| SLC12A9 | -0.0320520 |
| FHL1 | -0.0320566 |
| C1D | -0.0320817 |
| OR7G3 | -0.0320976 |
| C10orf118 | -0.0320993 |
| CLTCL1 | -0.0321061 |
| HYKK | -0.0321210 |
| GORAB | -0.0321326 |
| MST1R | -0.0321461 |
| ZNF256 | -0.0321591 |
| PRSS8 | -0.0321653 |
| HUS1 | -0.0321725 |
| TFR2 | -0.0321737 |
| EFNB2 | -0.0321779 |
| APLP2 | -0.0321794 |
| FZD5 | -0.0321813 |
| CEP250 | -0.0321832 |
| OR10G8 | -0.0321951 |
| SIX1 | -0.0322011 |
| KLF2 | -0.0322023 |
| RABGAP1 | -0.0322186 |
| LRRC10B | -0.0322243 |
| PRSS33 | -0.0322343 |
| PLG | -0.0322431 |
| MTMR11 | -0.0322746 |
| P4HA2 | -0.0322773 |
| LRRC55 | -0.0322802 |
| AP1G1 | -0.0322816 |
| STS | -0.0322888 |
| CCDC54 | -0.0323045 |
| RPE65 | -0.0323211 |
| UBL4B | -0.0323386 |
| WDR38 | -0.0323402 |
| C4orf17 | -0.0323496 |
| SCNN1B | -0.0323667 |
| CLDN19 | -0.0323671 |
| GSTZ1 | -0.0323690 |
| TMC2 | -0.0323852 |
| CYP3A5 | -0.0323957 |
| WDR7 | -0.0323970 |
| PNKD | -0.0324103 |
| RNF20 | -0.0324436 |
| ABHD16B | -0.0324565 |
| CNOT6 | -0.0324761 |
| FAM103A1 | -0.0324903 |
| ALAS2 | -0.0324907 |
| RAET1E | -0.0325016 |
| BBX | -0.0325026 |
| GALNT7 | -0.0325070 |
| SLC26A4 | -0.0325076 |
| TRAF6 | -0.0325114 |
| SH3RF3 | -0.0325141 |
| OLFML3 | -0.0325202 |
| FGFR1OP | -0.0325276 |
| INO80B | -0.0325280 |
| MRPL20 | -0.0325289 |
| ARMC2 | -0.0325312 |
| FBXO28 | -0.0325451 |
| TAS2R50 | -0.0325481 |
| GPR111 | -0.0325621 |
| GPALPP1 | -0.0325857 |
| RPGRIP1 | -0.0325908 |
| PSMA8 | -0.0325915 |
| OR10H1 | -0.0325999 |
| LINGO2 | -0.0326012 |
| MIR3654 | -0.0326082 |
| ADRA1A | -0.0326183 |
| KCNJ6 | -0.0326197 |
| HAUS2 | -0.0326254 |
| FEZ2 | -0.0326266 |
| NPHS2 | -0.0326409 |
| CCDC141 | -0.0326531 |
| SUN5 | -0.0326636 |
| ODAM | -0.0326685 |
| G2E3 | -0.0326708 |
| DFFB | -0.0326764 |
| IFNA10 | -0.0327229 |
| RPL38 | -0.0327387 |
| IL36A | -0.0327396 |
| ACTRT2 | -0.0327487 |
| SLC30A4 | -0.0327568 |
| ULBP3 | -0.0327569 |
| MBD3 | -0.0328037 |
| C9orf41 | -0.0328039 |
| HRSP12 | -0.0328059 |
| SASH1 | -0.0328240 |
| FABP1 | -0.0328245 |
| CMC4 | -0.0328252 |
| MAP7D2 | -0.0328271 |
| TMEM59 | -0.0328328 |
| PRDM2 | -0.0328717 |
| IFI27L1 | -0.0328925 |
| KLHDC8B | -0.0329019 |
| TAGLN3 | -0.0329112 |
| ANKRD66 | -0.0329130 |
| AANAT | -0.0329260 |
| MARCH10 | -0.0329370 |
| GAL3ST1 | -0.0329499 |
| ISL2 | -0.0329566 |
| PSME3 | -0.0329572 |
| USP25 | -0.0329638 |
| SNAP23 | -0.0329693 |
| CATSPERD | -0.0329793 |
| VPS16 | -0.0329820 |
| SNTB2 | -0.0330106 |
| TCEANC | -0.0330225 |
| OTOP3 | -0.0330226 |
| PTPLAD2 | -0.0330278 |
| TET2 | -0.0330777 |
| ATP6V0B | -0.0331113 |
| TAC3 | -0.0331203 |
| VEPH1 | -0.0331422 |
| TP53TG5 | -0.0331423 |
| OR13D1 | -0.0331483 |
| GSK3A | -0.0331563 |
| NUP188 | -0.0331792 |
| RFXAP | -0.0331880 |
| SENP2 | -0.0332067 |
| JOSD2 | -0.0332285 |
| E2F6 | -0.0332306 |
| SIRPD | -0.0332322 |
| APOD | -0.0332378 |
| TUBG1 | -0.0332410 |
| NAIF1 | -0.0332532 |
| EPT1 | -0.0332630 |
| DSG2 | -0.0332679 |
| ASNSD1 | -0.0332717 |
| FAM180A | -0.0333078 |
| PPOX | -0.0333125 |
| SHOX | -0.0333181 |
| FTSJ2 | -0.0333256 |
| HTR3C | -0.0333452 |
| ATOH1 | -0.0333702 |
| ALG14 | -0.0333741 |
| SSX2 | -0.0333761 |
| LARS2 | -0.0333857 |
| POT1 | -0.0333942 |
| PRLH | -0.0334289 |
| PCIF1 | -0.0334370 |
| F11 | -0.0334456 |
| ASB3 | -0.0334458 |
| NGB | -0.0334805 |
| KLF15 | -0.0334973 |
| TBC1D9B | -0.0335014 |
| OR2H2 | -0.0335090 |
| C1orf94 | -0.0335302 |
| PUF60 | -0.0335460 |
| ACBD6 | -0.0335615 |
| PHF12 | -0.0335650 |
| KLC2 | -0.0335786 |
| LCE3B | -0.0336258 |
| NXF5 | -0.0336283 |
| ISOC2 | -0.0336350 |
| DDX11 | -0.0336574 |
| OR5AK2 | -0.0336611 |
| C8orf59 | -0.0336792 |
| SPACA1 | -0.0336951 |
| NAP1L2 | -0.0337000 |
| FAM150B | -0.0337326 |
| ATAD3C | -0.0337482 |
| RPS6KA5 | -0.0337714 |
| SOX6 | -0.0337800 |
| KCNG4 | -0.0337907 |
| TMEM54 | -0.0337972 |
| TPCN1 | -0.0338032 |
| MUSK | -0.0338177 |
| KRTAP13-1 | -0.0338178 |
| NPFFR1 | -0.0338222 |
| CBY3 | -0.0338269 |
| TMOD2 | -0.0338432 |
| ADAMTSL1 | -0.0338487 |
| CS | -0.0338772 |
| TOP1 | -0.0338871 |
| TUFT1 | -0.0339198 |
| RSC1A1 | -0.0339538 |
| SNTG2 | -0.0339623 |
| NAGLU | -0.0339694 |
| ST7L | -0.0339900 |
| ELF1 | -0.0339903 |
| ADRA2B | -0.0340151 |
| TRIM49 | -0.0340520 |
| TRIM32 | -0.0340520 |
| PDIA2 | -0.0340678 |
| DNAJC11 | -0.0341028 |
| TAF7L | -0.0341157 |
| USP6 | -0.0341188 |
| STK35 | -0.0341347 |
| CAND2 | -0.0341359 |
| DLD | -0.0341590 |
| PLA2G5 | -0.0341664 |
| C9orf131 | -0.0341796 |
| APIP | -0.0342208 |
| PON1 | -0.0342293 |
| GDPD4 | -0.0342351 |
| ZSCAN22 | -0.0342486 |
| BCL2L10 | -0.0342498 |
| GNL3 | -0.0342591 |
| BBC3 | -0.0343011 |
| ZNF189 | -0.0343123 |
| GATC | -0.0343237 |
| AKTIP | -0.0343278 |
| TMEM179B | -0.0343366 |
| CRYGN | -0.0343935 |
| DLGAP1 | -0.0343944 |
| TUBA3C | -0.0343949 |
| COPS7A | -0.0343990 |
| SSB | -0.0344225 |
| PDCD6 | -0.0344375 |
| CRISPLD2 | -0.0344401 |
| MYF6 | -0.0344420 |
| RECQL5 | -0.0344761 |
| GUCA2B | -0.0344860 |
| LENEP | -0.0344983 |
| LRP5 | -0.0345055 |
| CISD2 | -0.0345063 |
| DTX1 | -0.0345073 |
| RER1 | -0.0345098 |
| GPRC6A | -0.0345312 |
| IFIT1 | -0.0345351 |
| KIRREL2 | -0.0345494 |
| PPP3R2 | -0.0345640 |
| POU4F3 | -0.0345662 |
| TSPY3 | -0.0345744 |
| TSPAN16 | -0.0345785 |
| RHAG | -0.0345978 |
| DENND2C | -0.0346032 |
| C19orf67 | -0.0346074 |
| GADD45GIP1 | -0.0346136 |
| PPHLN1 | -0.0346146 |
| IGSF8 | -0.0346171 |
| ASNA1 | -0.0346601 |
| CALCRL | -0.0346705 |
| SOS1 | -0.0346735 |
| ZNF592 | -0.0346854 |
| TCEANC2 | -0.0347005 |
| LIN52 | -0.0347068 |
| UBE2I | -0.0347110 |
| KRTAP8-1 | -0.0347144 |
| UPF3A | -0.0347251 |
| UPK2 | -0.0347270 |
| TMEM169 | -0.0347278 |
| WBSCR17 | -0.0347305 |
| ZNF714 | -0.0347447 |
| C7orf25 | -0.0347462 |
| PPIL4 | -0.0347633 |
| HS2ST1 | -0.0348095 |
| SEPP1 | -0.0348541 |
| SLC16A14 | -0.0348574 |
| VAV2 | -0.0348706 |
| WDR83OS | -0.0348844 |
| ZCCHC6 | -0.0349116 |
| FAM110A | -0.0349366 |
| CECR6 | -0.0349458 |
| SLC35E4 | -0.0349803 |
| KRTAP12-1 | -0.0349839 |
| CENPK | -0.0350023 |
| MPPE1 | -0.0350055 |
| KCNH8 | -0.0350129 |
| F2 | -0.0350365 |
| CHD8 | -0.0350455 |
| SF3B1 | -0.0350670 |
| PEX3 | -0.0350858 |
| MSTO1 | -0.0351093 |
| DNAH8 | -0.0351227 |
| CLEC1A | -0.0351372 |
| CHMP4C | -0.0351508 |
| PWWP2B | -0.0351629 |
| PDPR | -0.0351704 |
| FAM184A | -0.0351879 |
| GUCA1A | -0.0351912 |
| DUSP18 | -0.0351934 |
| MLH1 | -0.0352073 |
| GDF11 | -0.0352200 |
| SV2A | -0.0352541 |
| ZNF195 | -0.0352563 |
| C9orf91 | -0.0352626 |
| ACSM2A | -0.0352646 |
| QSER1 | -0.0352703 |
| SIPA1L2 | -0.0352803 |
| ZZZ3 | -0.0352936 |
| LATS1 | -0.0352961 |
| ZFYVE21 | -0.0352977 |
| ARHGDIG | -0.0353006 |
| KCNV1 | -0.0353007 |
| BCL7A | -0.0353224 |
| MARCH5 | -0.0353287 |
| PDE6A | -0.0353395 |
| ISCA1 | -0.0353477 |
| ZCCHC18 | -0.0353559 |
| COX8A | -0.0353621 |
| OR4K17 | -0.0353971 |
| NTN3 | -0.0354001 |
| GPR22 | -0.0354022 |
| POF1B | -0.0354039 |
| MICU1 | -0.0354210 |
| MRPL55 | -0.0354211 |
| SLC17A6 | -0.0354268 |
| KRTAP2-3 | -0.0354288 |
| C1orf35 | -0.0354383 |
| SUN3 | -0.0354522 |
| SYNE3 | -0.0354541 |
| MAST1 | -0.0354673 |
| CCL16 | -0.0354966 |
| MGST3 | -0.0354966 |
| PAK3 | -0.0355218 |
| RPAP2 | -0.0355318 |
| VWA8 | -0.0355577 |
| NID2 | -0.0355725 |
| KCNK16 | -0.0355763 |
| ITFG2 | -0.0355765 |
| SLC13A4 | -0.0355853 |
| CSRNP1 | -0.0355857 |
| CRYBB3 | -0.0356101 |
| MOGAT3 | -0.0356208 |
| C2orf61 | -0.0356396 |
| DCUN1D3 | -0.0356535 |
| SEC23IP | -0.0356541 |
| HNRNPM | -0.0356557 |
| IFNA4 | -0.0356690 |
| SLCO3A1 | -0.0356790 |
| PRR5L | -0.0356880 |
| KANSL2 | -0.0356882 |
| SPIRE2 | -0.0356885 |
| CSRP3 | -0.0357003 |
| CLN5 | -0.0357090 |
| PEX5 | -0.0357396 |
| MAPK8 | -0.0357643 |
| CMTM5 | -0.0357694 |
| SMAD2 | -0.0357701 |
| C6orf58 | -0.0357803 |
| OR51D1 | -0.0357931 |
| SLC38A6 | -0.0357962 |
| HAUS5 | -0.0357966 |
| NAA16 | -0.0357993 |
| REM1 | -0.0358147 |
| PSKH2 | -0.0358234 |
| UGT3A1 | -0.0358323 |
| MLLT1 | -0.0358406 |
| TBC1D8B | -0.0358745 |
| ACADVL | -0.0358891 |
| HMGA2 | -0.0358980 |
| RAB31 | -0.0359141 |
| MLYCD | -0.0359331 |
| GNB2L1 | -0.0359385 |
| SAT2 | -0.0359393 |
| PALB2 | -0.0359589 |
| ADAT1 | -0.0359611 |
| KLF9 | -0.0359864 |
| TMEM19 | -0.0359944 |
| TMEM75 | -0.0359986 |
| EIF4E | -0.0360019 |
| ZNF501 | -0.0360025 |
| LZTS2 | -0.0360039 |
| TMTC4 | -0.0360045 |
| SCFD1 | -0.0360363 |
| DHDDS | -0.0360425 |
| WNT7A | -0.0360441 |
| BSG | -0.0360541 |
| GFPT1 | -0.0360694 |
| EYA3 | -0.0360705 |
| FAM169B | -0.0360744 |
| METTL7B | -0.0360849 |
| LCE3D | -0.0360939 |
| OTOS | -0.0361086 |
| PYROXD1 | -0.0361123 |
| SCAF8 | -0.0361156 |
| ING3 | -0.0361506 |
| GMCL1 | -0.0361948 |
| MED10 | -0.0361994 |
| FAM126B | -0.0362030 |
| ELF2 | -0.0362032 |
| GPR32 | -0.0362053 |
| ADORA3 | -0.0362166 |
| HTR3A | -0.0362318 |
| TMEM74 | -0.0362349 |
| NME6 | -0.0362377 |
| ZNHIT6 | -0.0362788 |
| KIAA1211 | -0.0363281 |
| DHRS4 | -0.0363533 |
| RP1L1 | -0.0363543 |
| TBL1Y | -0.0363604 |
| TMEM81 | -0.0363676 |
| SLC39A11 | -0.0363686 |
| CHRNA2 | -0.0363863 |
| MTA1 | -0.0363934 |
| ANKLE1 | -0.0364045 |
| PXN | -0.0364055 |
| FTMT | -0.0364066 |
| SMURF1 | -0.0364148 |
| C15orf40 | -0.0364151 |
| C15orf32 | -0.0364598 |
| HBQ1 | -0.0364649 |
| SEC31A | -0.0364701 |
| RGS7BP | -0.0364783 |
| KRI1 | -0.0365158 |
| CTAGE4 | -0.0365174 |
| THBS3 | -0.0365174 |
| USP46 | -0.0365219 |
| PRM1 | -0.0365519 |
| SLC5A3 | -0.0365603 |
| NGRN | -0.0365689 |
| PROK1 | -0.0365807 |
| WDR55 | -0.0365971 |
| MAB21L2 | -0.0366126 |
| PRKAR1B | -0.0366160 |
| DMXL2 | -0.0366389 |
| LRP1 | -0.0366415 |
| HAAO | -0.0366477 |
| DIMT1 | -0.0366600 |
| IL31RA | -0.0366744 |
| PFKFB3 | -0.0366776 |
| POLR2G | -0.0366799 |
| MYL1 | -0.0366804 |
| VCAN | -0.0366823 |
| ACYP2 | -0.0366920 |
| TACR3 | -0.0367363 |
| MYT1L | -0.0367550 |
| SMCO2 | -0.0367551 |
| REG1A | -0.0367655 |
| SEMA3A | -0.0367791 |
| GCK | -0.0367874 |
| RASIP1 | -0.0367983 |
| SHC1 | -0.0368020 |
| CDX2 | -0.0368133 |
| SLC2A13 | -0.0368140 |
| MICAL2 | -0.0368143 |
| PAIP1 | -0.0368461 |
| BRD2 | -0.0368573 |
| OR1N2 | -0.0368620 |
| SYNGR2 | -0.0368637 |
| GJC1 | -0.0368774 |
| TMEM185A | -0.0368807 |
| RTFDC1 | -0.0368856 |
| DNAJC8 | -0.0369083 |
| FIBP | -0.0369578 |
| ZNHIT1 | -0.0369702 |
| CSH2 | -0.0369759 |
| LYZL4 | -0.0369787 |
| F5 | -0.0369894 |
| ATRAID | -0.0370044 |
| HNMT | -0.0370057 |
| BTBD16 | -0.0370191 |
| MAP3K7CL | -0.0370226 |
| SMG7 | -0.0370540 |
| NAA15 | -0.0370771 |
| USP44 | -0.0370813 |
| KCNV2 | -0.0370827 |
| GPATCH11 | -0.0370833 |
| FAM71E2 | -0.0370940 |
| NKX2-8 | -0.0371041 |
| TSR2 | -0.0371062 |
| NLRP9 | -0.0371066 |
| OR4K1 | -0.0371117 |
| FZD2 | -0.0371125 |
| NXPE1 | -0.0371602 |
| CR1 | -0.0371845 |
| GP6 | -0.0372153 |
| ASCL3 | -0.0372232 |
| CD248 | -0.0372671 |
| SLC5A9 | -0.0372691 |
| GPR141 | -0.0373011 |
| RPS4X | -0.0373460 |
| FOXA3 | -0.0373486 |
| SMARCD1 | -0.0373492 |
| PMP22 | -0.0373795 |
| ALS2CL | -0.0373945 |
| BCAN | -0.0374061 |
| NDUFB7 | -0.0374169 |
| SF3B4 | -0.0374238 |
| MECP2 | -0.0374253 |
| ADIG | -0.0374393 |
| VAMP1 | -0.0374720 |
| SMARCC2 | -0.0374746 |
| ST8SIA3 | -0.0374841 |
| CEBPZ | -0.0374940 |
| DHX32 | -0.0375055 |
| NEXN | -0.0375142 |
| KNG1 | -0.0375208 |
| RIN2 | -0.0375479 |
| PSMC6 | -0.0375541 |
| TBC1D32 | -0.0375851 |
| NLGN1 | -0.0375917 |
| GBX2 | -0.0375937 |
| DSG4 | -0.0376062 |
| FAM181B | -0.0376081 |
| MAEA | -0.0376205 |
| EHD3 | -0.0376277 |
| AADACL2 | -0.0376372 |
| ABCB1 | -0.0376516 |
| GTF2H3 | -0.0376527 |
| TMEM174 | -0.0376599 |
| REC8 | -0.0376803 |
| EPB42 | -0.0376853 |
| OR2A7 | -0.0376922 |
| NOL8 | -0.0376958 |
| POU5F1 | -0.0377034 |
| TAF6 | -0.0377129 |
| SPATA2L | -0.0377360 |
| BCL7C | -0.0377399 |
| NLRP8 | -0.0377832 |
| GBAS | -0.0377839 |
| C17orf105 | -0.0378073 |
| MIA3 | -0.0378077 |
| COLEC12 | -0.0378189 |
| PSKH1 | -0.0378198 |
| CLCN6 | -0.0378238 |
| ZNF646 | -0.0378239 |
| AP4S1 | -0.0378287 |
| ACSF3 | -0.0378347 |
| KEAP1 | -0.0378384 |
| USP11 | -0.0378740 |
| ECHDC3 | -0.0378840 |
| ADAM12 | -0.0378896 |
| SMARCA4 | -0.0379018 |
| DDX17 | -0.0379087 |
| SLC25A32 | -0.0379300 |
| PPTC7 | -0.0379335 |
| TSSK4 | -0.0379434 |
| FGF4 | -0.0379486 |
| IL36B | -0.0379606 |
| SYT2 | -0.0379606 |
| LRRTM3 | -0.0379648 |
| GPR52 | -0.0379775 |
| IMPG1 | -0.0379946 |
| NAA30 | -0.0379948 |
| TMEM108 | -0.0380096 |
| A3GALT2 | -0.0380097 |
| S100A5 | -0.0380263 |
| SOX21 | -0.0380346 |
| MADCAM1 | -0.0380377 |
| ANK2 | -0.0380725 |
| ATXN7 | -0.0380740 |
| MAF1 | -0.0381059 |
| RTP3 | -0.0381091 |
| CADM4 | -0.0381121 |
| EFNA1 | -0.0381575 |
| RABGGTB | -0.0382017 |
| ANTXR1 | -0.0382305 |
| HCRTR2 | -0.0382820 |
| CUL7 | -0.0382847 |
| OR5P3 | -0.0382936 |
| TXNRD2 | -0.0383135 |
| CLN3 | -0.0383167 |
| HDAC3 | -0.0383172 |
| GTF2A2 | -0.0383174 |
| ZNF641 | -0.0383179 |
| KLK12 | -0.0383249 |
| SH3TC2 | -0.0383270 |
| FDXACB1 | -0.0383300 |
| NKD2 | -0.0383325 |
| ATG4B | -0.0383396 |
| GPR83 | -0.0383458 |
| WDR25 | -0.0383648 |
| CDA | -0.0383666 |
| NRG4 | -0.0383689 |
| BHLHE41 | -0.0383751 |
| CYP2W1 | -0.0383790 |
| C9orf53 | -0.0383842 |
| RPL36 | -0.0383958 |
| DSCAM | -0.0384020 |
| EIF2D | -0.0384096 |
| FAM186B | -0.0384150 |
| FANCF | -0.0384461 |
| SPATA31E1 | -0.0384717 |
| IRX3 | -0.0384742 |
| ALOX15 | -0.0384767 |
| TMEM245 | -0.0384900 |
| SLC25A10 | -0.0384991 |
| OR1C1 | -0.0385273 |
| PSG11 | -0.0385317 |
| SEZ6 | -0.0385334 |
| FEV | -0.0385447 |
| ATP5S | -0.0385459 |
| TAS1R2 | -0.0385562 |
| USP5 | -0.0385633 |
| C6orf123 | -0.0385649 |
| SAFB | -0.0385698 |
| ADCK3 | -0.0385864 |
| AEBP1 | -0.0386104 |
| KCTD10 | -0.0386240 |
| ADAM7 | -0.0386689 |
| GPR128 | -0.0386849 |
| NCOA5 | -0.0386935 |
| NUTM1 | -0.0386957 |
| GLIS3 | -0.0386996 |
| PITPNM2 | -0.0387019 |
| HMGB4 | -0.0387111 |
| PLAA | -0.0387163 |
| ATP2B3 | -0.0387256 |
| NSFL1C | -0.0387327 |
| AGPAT9 | -0.0387508 |
| SFT2D3 | -0.0387511 |
| CHCHD7 | -0.0387710 |
| SDR16C5 | -0.0388081 |
| ALG10 | -0.0388409 |
| FDX1L | -0.0388586 |
| PRDM11 | -0.0388699 |
| GDPD1 | -0.0388763 |
| METTL16 | -0.0388764 |
| SAV1 | -0.0388848 |
| PBX3 | -0.0389170 |
| PCDHA8 | -0.0389305 |
| RPLP0 | -0.0389552 |
| UBTD1 | -0.0389566 |
| SSX4B | -0.0389639 |
| LOH12CR1 | -0.0389716 |
| XRCC1 | -0.0389992 |
| IGFBP1 | -0.0390046 |
| PRODH2 | -0.0390076 |
| DDX60L | -0.0390151 |
| SYT15 | -0.0390161 |
| HECW2 | -0.0390181 |
| CGB | -0.0390228 |
| NET1 | -0.0390438 |
| KRTAP1-5 | -0.0390463 |
| ATRN | -0.0390562 |
| METTL5 | -0.0390590 |
| IGFN1 | -0.0390598 |
| RPS24 | -0.0390686 |
| COX15 | -0.0390687 |
| OPN1MW | -0.0390818 |
| TRHR | -0.0390827 |
| AKNAD1 | -0.0390895 |
| SDS | -0.0391085 |
| KMT2E | -0.0391539 |
| CAMKMT | -0.0391540 |
| FHAD1 | -0.0391683 |
| NGEF | -0.0391718 |
| RORB | -0.0391955 |
| SLC16A7 | -0.0392063 |
| PPP1R13B | -0.0392239 |
| TM2D3 | -0.0392257 |
| GOLGA8I | -0.0392308 |
| LPPR4 | -0.0392335 |
| KCTD16 | -0.0392362 |
| UNC45A | -0.0392369 |
| ATP4B | -0.0392688 |
| MPND | -0.0392842 |
| CCDC60 | -0.0393153 |
| CIB1 | -0.0393180 |
| NPTXR | -0.0393282 |
| EP300 | -0.0393341 |
| NDST3 | -0.0393411 |
| CALHM2 | -0.0393425 |
| PRAMEF10 | -0.0393461 |
| OR1A2 | -0.0393825 |
| THOC6 | -0.0393988 |
| CHCHD1 | -0.0394028 |
| KRT27 | -0.0394034 |
| CLCNKB | -0.0394249 |
| HOXA1 | -0.0394553 |
| TAS2R7 | -0.0394601 |
| VPS29 | -0.0394639 |
| TGM7 | -0.0394748 |
| CDH12 | -0.0395091 |
| LMBRD2 | -0.0395224 |
| ZFP1 | -0.0395244 |
| NPR1 | -0.0395333 |
| ZNF157 | -0.0395405 |
| TMC1 | -0.0395960 |
| SERPINA10 | -0.0396036 |
| NPVF | -0.0396120 |
| ARHGAP42 | -0.0396248 |
| ACSS2 | -0.0396718 |
| TSPAN8 | -0.0397036 |
| FN3K | -0.0397093 |
| BZW2 | -0.0397251 |
| OR2W1 | -0.0397306 |
| DDX54 | -0.0397319 |
| EIF2A | -0.0397408 |
| RUNX2 | -0.0397409 |
| MYH2 | -0.0397412 |
| METTL6 | -0.0397453 |
| LEPRE1 | -0.0397554 |
| ATP6V1A | -0.0397581 |
| CYP2C9 | -0.0397687 |
| COLGALT2 | -0.0397743 |
| SCGN | -0.0397787 |
| LACTB2 | -0.0397823 |
| NEDD1 | -0.0397875 |
| CMAS | -0.0397878 |
| GRK1 | -0.0398024 |
| TRIM50 | -0.0398073 |
| DNAH2 | -0.0398086 |
| SLC2A1 | -0.0398542 |
| SLC6A15 | -0.0398726 |
| BET1L | -0.0398775 |
| MCM3AP | -0.0398829 |
| NETO1 | -0.0398898 |
| MYO7B | -0.0399069 |
| PKLR | -0.0399105 |
| RCE1 | -0.0399175 |
| C1QTNF1 | -0.0399236 |
| RAB37 | -0.0399445 |
| CAMKK2 | -0.0399647 |
| CYP3A7 | -0.0399987 |
| KLHL26 | -0.0400073 |
| SUPT4H1 | -0.0400143 |
| VPS8 | -0.0400458 |
| GDNF | -0.0400575 |
| SLC6A13 | -0.0400637 |
| C20orf141 | -0.0400718 |
| RAPGEF2 | -0.0400776 |
| PRUNE | -0.0400909 |
| LZTS1 | -0.0401043 |
| KCNS3 | -0.0401102 |
| PUM1 | -0.0401756 |
| CLIP2 | -0.0401870 |
| CXorf57 | -0.0401900 |
| POLR2A | -0.0402073 |
| SMPD1 | -0.0402386 |
| ABCB10 | -0.0402582 |
| RNASE8 | -0.0402818 |
| MAN1C1 | -0.0402960 |
| PSMF1 | -0.0403089 |
| SLC22A8 | -0.0403153 |
| KIF5A | -0.0403329 |
| MBTD1 | -0.0403449 |
| AQP10 | -0.0403552 |
| C16orf70 | -0.0403910 |
| DNHD1 | -0.0403927 |
| ANKRD55 | -0.0403973 |
| ZNF488 | -0.0404050 |
| DNAH10 | -0.0404074 |
| KRT10 | -0.0404224 |
| PHF3 | -0.0404609 |
| IQCF6 | -0.0404697 |
| CD207 | -0.0404895 |
| PRG3 | -0.0405119 |
| TRPC3 | -0.0405122 |
| DSCR4 | -0.0405132 |
| CD2AP | -0.0405198 |
| EXOC6B | -0.0405279 |
| HIAT1 | -0.0405375 |
| ACTR6 | -0.0405476 |
| KIAA0907 | -0.0405763 |
| PGA3 | -0.0405765 |
| CXCL5 | -0.0405834 |
| WFDC8 | -0.0405890 |
| C17orf47 | -0.0405908 |
| FAM19A1 | -0.0406018 |
| NVL | -0.0406305 |
| USP22 | -0.0406323 |
| SCN2A | -0.0406569 |
| MYADML2 | -0.0406624 |
| GOLGA2 | -0.0406709 |
| ABHD4 | -0.0407065 |
| ZFYVE1 | -0.0407171 |
| HBE1 | -0.0407557 |
| CEP97 | -0.0407763 |
| PIGK | -0.0407909 |
| FBXO33 | -0.0407983 |
| CCDC17 | -0.0408310 |
| CPSF7 | -0.0408316 |
| ADARB1 | -0.0408580 |
| DCHS2 | -0.0408695 |
| AMZ2 | -0.0408778 |
| FUT9 | -0.0408812 |
| PCDHB17 | -0.0408984 |
| FADS6 | -0.0409425 |
| OR2F1 | -0.0409450 |
| OBSL1 | -0.0409501 |
| PCDH20 | -0.0409704 |
| C11orf82 | -0.0410039 |
| WNT7B | -0.0410239 |
| GOLGA8A | -0.0410277 |
| GH2 | -0.0410682 |
| ACRV1 | -0.0410754 |
| PQLC2 | -0.0410987 |
| ASB4 | -0.0411068 |
| TSC22D3 | -0.0411232 |
| SLC29A3 | -0.0411269 |
| CPA5 | -0.0411341 |
| RNF207 | -0.0411794 |
| GCN1L1 | -0.0411819 |
| UNC13B | -0.0411850 |
| RBM12B-AS1 | -0.0411885 |
| POM121 | -0.0411898 |
| DPM3 | -0.0412003 |
| PFDN1 | -0.0412076 |
| TEX13B | -0.0412424 |
| LCN1 | -0.0412556 |
| PRG2 | -0.0412590 |
| RGMB | -0.0412611 |
| WNT9A | -0.0412648 |
| ESAM | -0.0412711 |
| OR2J2 | -0.0412779 |
| HIST1H3F | -0.0413396 |
| ITGAV | -0.0413402 |
| VWF | -0.0413483 |
| SNRNP40 | -0.0413776 |
| SLC4A2 | -0.0413815 |
| GON4L | -0.0413884 |
| KANSL1L | -0.0413986 |
| TFCP2 | -0.0414040 |
| TBX6 | -0.0414051 |
| ASB5 | -0.0414085 |
| ENAH | -0.0414184 |
| MC4R | -0.0414246 |
| DNAJB7 | -0.0414367 |
| TVP23C-CDRT4 | -0.0414611 |
| SLC22A13 | -0.0414716 |
| LIN7C | -0.0414720 |
| HYAL4 | -0.0414744 |
| RIMBP2 | -0.0414810 |
| MUC12 | -0.0415093 |
| ZNF576 | -0.0415348 |
| MYCBP | -0.0415495 |
| DEFB123 | -0.0415509 |
| HTR6 | -0.0415617 |
| PKD1L1 | -0.0415641 |
| ADSS | -0.0415660 |
| HERC1 | -0.0415730 |
| GCC2 | -0.0416074 |
| RNF152 | -0.0416214 |
| ZC3H8 | -0.0416391 |
| UST | -0.0416534 |
| PTAR1 | -0.0416906 |
| CYP3A4 | -0.0417242 |
| CCDC108 | -0.0417252 |
| MCM9 | -0.0417319 |
| DEFB106B | -0.0417472 |
| FATE1 | -0.0417583 |
| SHCBP1L | -0.0417627 |
| NDUFB6 | -0.0417680 |
| MTF1 | -0.0417817 |
| GLP1R | -0.0417858 |
| ZBTB7C | -0.0417963 |
| C2orf80 | -0.0418002 |
| MRPL54 | -0.0418306 |
| SLC35D1 | -0.0418345 |
| BRE | -0.0418345 |
| TTC32 | -0.0418414 |
| LTB4R | -0.0418478 |
| TSSK1B | -0.0418493 |
| NECAB2 | -0.0418553 |
| GOT1L1 | -0.0418630 |
| ZNF526 | -0.0418692 |
| ZNF649 | -0.0418735 |
| DCTD | -0.0418886 |
| RPS4Y1 | -0.0418895 |
| TXNL1 | -0.0419200 |
| TRAPPC6B | -0.0419301 |
| SNIP1 | -0.0419685 |
| ZNRF4 | -0.0419691 |
| ZNF560 | -0.0419697 |
| OR2C3 | -0.0419748 |
| TMEM8A | -0.0420047 |
| EFCAB4A | -0.0420088 |
| GJD2 | -0.0420288 |
| PRSS36 | -0.0420350 |
| TMOD3 | -0.0420441 |
| DBNDD1 | -0.0420443 |
| KRTAP9-3 | -0.0420467 |
| ANKRD12 | -0.0420658 |
| FXYD4 | -0.0420679 |
| TAS2R5 | -0.0421035 |
| PRKACA | -0.0421054 |
| CST8 | -0.0421116 |
| ITGA11 | -0.0421132 |
| PMVK | -0.0421172 |
| PTPN5 | -0.0421401 |
| MPZ | -0.0421496 |
| RNF11 | -0.0421519 |
| DCAF4L2 | -0.0421554 |
| SAMD7 | -0.0421796 |
| PGBD3 | -0.0421913 |
| WDR89 | -0.0422077 |
| GPR88 | -0.0422280 |
| PLXNA4 | -0.0422404 |
| CAPN14 | -0.0422539 |
| VWA3B | -0.0422556 |
| ZNF513 | -0.0422606 |
| TMEM119 | -0.0422808 |
| OTUD1 | -0.0422819 |
| MGA | -0.0422977 |
| SERPIND1 | -0.0422978 |
| GPR17 | -0.0423155 |
| THRAP3 | -0.0423533 |
| PPP6R2 | -0.0423650 |
| OR2V2 | -0.0423968 |
| KLHL30 | -0.0424071 |
| SLC35E1 | -0.0424115 |
| MATN1 | -0.0424374 |
| PPAN-P2RY11 | -0.0424404 |
| BTBD3 | -0.0424463 |
| MEP1A | -0.0424504 |
| CASP12 | -0.0424563 |
| C3orf49 | -0.0424663 |
| IBA57 | -0.0424869 |
| TRPM4 | -0.0424904 |
| ARF6 | -0.0425035 |
| KIAA2026 | -0.0425051 |
| SERPINB13 | -0.0425089 |
| TGM4 | -0.0425204 |
| CASK | -0.0425259 |
| SP5 | -0.0425268 |
| CARNS1 | -0.0425448 |
| C5orf51 | -0.0425632 |
| ZNF511 | -0.0425768 |
| VPREB1 | -0.0425862 |
| FLOT1 | -0.0425909 |
| POLRMT | -0.0425922 |
| ATXN7L3B | -0.0425950 |
| ZNF382 | -0.0425960 |
| TMED10 | -0.0425990 |
| CDH10 | -0.0426032 |
| PSG5 | -0.0426096 |
| AGBL1 | -0.0426120 |
| DYNC1I1 | -0.0426241 |
| KIAA1614 | -0.0426253 |
| MYL4 | -0.0426333 |
| VWA9 | -0.0426337 |
| TMED6 | -0.0426372 |
| MBD2 | -0.0426435 |
| PEX7 | -0.0426518 |
| CENPC | -0.0426610 |
| GPR37L1 | -0.0426660 |
| MCEE | -0.0426950 |
| PHLPP2 | -0.0427096 |
| LIMD1 | -0.0427119 |
| SECISBP2 | -0.0427286 |
| RBP2 | -0.0427405 |
| LINS | -0.0427413 |
| OPALIN | -0.0427414 |
| CNKSR2 | -0.0427517 |
| STOML1 | -0.0427650 |
| MYH15 | -0.0427727 |
| GGCX | -0.0427786 |
| RPS4Y2 | -0.0427830 |
| SARS | -0.0427846 |
| EXOC4 | -0.0427885 |
| TBC1D25 | -0.0428015 |
| C17orf98 | -0.0428072 |
| ESR2 | -0.0428136 |
| PARG | -0.0428209 |
| USP51 | -0.0428428 |
| C1orf123 | -0.0428713 |
| FGD4 | -0.0428793 |
| ECSCR | -0.0428801 |
| C7orf73 | -0.0428813 |
| ERAS | -0.0428848 |
| SPG7 | -0.0428896 |
| CAV2 | -0.0428899 |
| AHDC1 | -0.0429161 |
| MARCH3 | -0.0429500 |
| KIR3DL2 | -0.0429581 |
| EOGT | -0.0429582 |
| CMTM4 | -0.0429812 |
| MYO3B | -0.0430053 |
| H2AFV | -0.0430178 |
| MRPS10 | -0.0430259 |
| LRRC4B | -0.0430268 |
| FAHD2A | -0.0430292 |
| MINPP1 | -0.0430302 |
| CRTC3 | -0.0430414 |
| NDUFA4L2 | -0.0430436 |
| ZNF473 | -0.0430460 |
| CA11 | -0.0430572 |
| TOPORS | -0.0430586 |
| PDLIM5 | -0.0430985 |
| COPB1 | -0.0431000 |
| HDAC7 | -0.0431184 |
| MBD3L1 | -0.0431360 |
| TXLNA | -0.0431387 |
| TRMT2A | -0.0431457 |
| RNF148 | -0.0431511 |
| FBXO11 | -0.0431575 |
| C21orf49 | -0.0431882 |
| OR2A25 | -0.0431948 |
| STK11IP | -0.0432051 |
| RPL18 | -0.0432099 |
| ZBTB39 | -0.0432114 |
| TMEM167B | -0.0432208 |
| CCDC85B | -0.0432237 |
| OTOP1 | -0.0432282 |
| FAM132A | -0.0432439 |
| ZNF845 | -0.0432459 |
| CDHR2 | -0.0432676 |
| HTR1B | -0.0432866 |
| ENOX1 | -0.0432890 |
| RPP25L | -0.0433014 |
| DDX10 | -0.0433059 |
| NLRP4 | -0.0433133 |
| DUSP3 | -0.0433133 |
| RSRC2 | -0.0433290 |
| ZNF222 | -0.0433310 |
| BAP1 | -0.0433327 |
| NUPL1 | -0.0433392 |
| TMEM179 | -0.0433422 |
| GPR153 | -0.0433515 |
| SCTR | -0.0433713 |
| ADCY10 | -0.0433763 |
| ACSF2 | -0.0433767 |
| SPATA22 | -0.0434075 |
| LRRC47 | -0.0434165 |
| ZNF253 | -0.0434273 |
| FERD3L | -0.0434284 |
| METAP2 | -0.0434367 |
| PDZD3 | -0.0434796 |
| ANAPC15 | -0.0434898 |
| AGPAT4 | -0.0435193 |
| C11orf40 | -0.0435359 |
| GRHPR | -0.0435409 |
| ZSCAN9 | -0.0435574 |
| LEUTX | -0.0435683 |
| PTPN21 | -0.0435742 |
| KCNRG | -0.0435941 |
| OR10R2 | -0.0435998 |
| PRCP | -0.0436031 |
| UBL5 | -0.0436127 |
| TGFB2 | -0.0436268 |
| OR51Q1 | -0.0436548 |
| KRT38 | -0.0436560 |
| RAC3 | -0.0436883 |
| C17orf89 | -0.0436949 |
| CHD2 | -0.0437008 |
| SLC38A9 | -0.0437054 |
| ERGIC3 | -0.0437173 |
| POMK | -0.0437197 |
| LAMA4 | -0.0437364 |
| LLPH | -0.0437409 |
| PCDHB1 | -0.0437537 |
| LDOC1 | -0.0437629 |
| ANKFN1 | -0.0437905 |
| LPO | -0.0437931 |
| SOCS6 | -0.0437983 |
| HTR3B | -0.0438240 |
| ASTL | -0.0438352 |
| RGAG1 | -0.0438609 |
| BMP8B | -0.0438682 |
| RABGGTA | -0.0438710 |
| A4GALT | -0.0438737 |
| KRTAP3-3 | -0.0438770 |
| TMEM204 | -0.0438801 |
| RAB13 | -0.0438880 |
| PRKACB | -0.0439157 |
| CENPT | -0.0439290 |
| GNRH2 | -0.0439495 |
| SELT | -0.0439501 |
| PNISR | -0.0439532 |
| FGF22 | -0.0439546 |
| PRM2 | -0.0439621 |
| CBX6 | -0.0439655 |
| MAGEB10 | -0.0439713 |
| SERPINA7 | -0.0439763 |
| BCKDK | -0.0439819 |
| L1CAM | -0.0439844 |
| ARR3 | -0.0439889 |
| PPM1L | -0.0439987 |
| CNNM1 | -0.0440206 |
| ZSWIM7 | -0.0440366 |
| IER3 | -0.0440580 |
| UBE2D2 | -0.0440672 |
| EPHA7 | -0.0440694 |
| MAP10 | -0.0440700 |
| PNPLA8 | -0.0440812 |
| TBC1D26 | -0.0440813 |
| KRTAP4-9 | -0.0441168 |
| VSTM2B | -0.0441180 |
| GIP | -0.0441262 |
| NADSYN1 | -0.0441325 |
| IFNA5 | -0.0441485 |
| LRRC72 | -0.0441585 |
| IL36RN | -0.0441590 |
| CHMP6 | -0.0441852 |
| CXorf56 | -0.0441877 |
| FSHB | -0.0442130 |
| GALR1 | -0.0442223 |
| OMG | -0.0442319 |
| SNTA1 | -0.0442356 |
| LRP10 | -0.0442358 |
| SFTPA1 | -0.0442770 |
| EREG | -0.0442793 |
| UFSP2 | -0.0443148 |
| USP4 | -0.0443416 |
| AGAP7 | -0.0443438 |
| RPL12 | -0.0443618 |
| TRMT112 | -0.0443666 |
| USP9X | -0.0443902 |
| RPS29 | -0.0444065 |
| TEX35 | -0.0444249 |
| AIMP2 | -0.0444422 |
| KLHL8 | -0.0444863 |
| SEMA3D | -0.0444996 |
| ALDH8A1 | -0.0445073 |
| HK1 | -0.0445166 |
| PANX2 | -0.0445271 |
| TMEM133 | -0.0445410 |
| ZNHIT2 | -0.0445517 |
| DCAF8L2 | -0.0445785 |
| CHRDL2 | -0.0445794 |
| PAPOLB | -0.0446012 |
| SNX32 | -0.0446115 |
| DKKL1 | -0.0446207 |
| PTGR1 | -0.0446252 |
| ADCYAP1R1 | -0.0446274 |
| SMC5 | -0.0446285 |
| MRPS18C | -0.0446450 |
| NFE2L2 | -0.0446590 |
| HNRNPK | -0.0446612 |
| RAB6C | -0.0446656 |
| OR7A5 | -0.0446690 |
| EMC9 | -0.0446776 |
| THRB | -0.0447071 |
| ZNF619 | -0.0447076 |
| MIXL1 | -0.0447092 |
| ELSPBP1 | -0.0447232 |
| TMEM126A | -0.0447332 |
| SYNGR3 | -0.0447356 |
| SNX19 | -0.0447737 |
| MYO1C | -0.0447915 |
| SCARF2 | -0.0448036 |
| OR1Q1 | -0.0448080 |
| OR4F4 | -0.0448120 |
| ZNF830 | -0.0448211 |
| RCHY1 | -0.0448342 |
| STX2 | -0.0448438 |
| LAMB1 | -0.0448455 |
| HIST1H1D | -0.0448539 |
| NDUFS7 | -0.0448657 |
| AGPAT1 | -0.0448667 |
| ACTL9 | -0.0448708 |
| SGIP1 | -0.0448945 |
| ACAP3 | -0.0448990 |
| CCDC174 | -0.0449204 |
| ADAM18 | -0.0449247 |
| RELL2 | -0.0449492 |
| TTLL6 | -0.0449587 |
| PDE10A | -0.0449859 |
| AKAP6 | -0.0450060 |
| GRM3 | -0.0450113 |
| ZCCHC5 | -0.0450434 |
| AVPR1B | -0.0450495 |
| DEFB104B | -0.0450796 |
| CCT5 | -0.0450922 |
| SHQ1 | -0.0451053 |
| SPHKAP | -0.0451183 |
| DGCR6 | -0.0451273 |
| C3orf27 | -0.0451398 |
| C11orf83 | -0.0451456 |
| HHLA3 | -0.0451574 |
| CNOT4 | -0.0451635 |
| ZNF75D | -0.0451764 |
| SCAND3 | -0.0451886 |
| YTHDF3 | -0.0451983 |
| CREB3L3 | -0.0451989 |
| FCF1 | -0.0452084 |
| ANKRD13B | -0.0452181 |
| RXFP2 | -0.0452198 |
| ZNF273 | -0.0452283 |
| RNF113B | -0.0452330 |
| NAP1L4 | -0.0452349 |
| ZSCAN21 | -0.0452530 |
| TPTE2 | -0.0452535 |
| ZNF674 | -0.0452536 |
| CISD1 | -0.0452636 |
| SLC25A12 | -0.0452637 |
| MRPL32 | -0.0453025 |
| ATP2A2 | -0.0453418 |
| TM4SF5 | -0.0453493 |
| HOXB8 | -0.0453688 |
| C21orf37 | -0.0453913 |
| KRTAP13-3 | -0.0453972 |
| CELF1 | -0.0454084 |
| KLK3 | -0.0454248 |
| SCN5A | -0.0454267 |
| WDR61 | -0.0454511 |
| NTPCR | -0.0454541 |
| SPANXN3 | -0.0454572 |
| IFNA21 | -0.0454619 |
| TBC1D20 | -0.0454780 |
| TIRAP | -0.0454872 |
| FGF8 | -0.0454968 |
| ZNF3 | -0.0454983 |
| D2HGDH | -0.0455418 |
| KLHL2 | -0.0455584 |
| RNF10 | -0.0455628 |
| ADCY2 | -0.0455741 |
| NDUFAB1 | -0.0455803 |
| SCG3 | -0.0455882 |
| PTF1A | -0.0455987 |
| ZNF566 | -0.0456151 |
| TMBIM6 | -0.0456375 |
| ENPP7 | -0.0456491 |
| ATP13A4 | -0.0456604 |
| ATP5H | -0.0456627 |
| C3orf80 | -0.0456722 |
| DAAM1 | -0.0456726 |
| KRTAP4-2 | -0.0456972 |
| DIRC1 | -0.0456985 |
| TMC5 | -0.0456999 |
| MLLT11 | -0.0457034 |
| TULP2 | -0.0457063 |
| MRGPRX3 | -0.0457139 |
| DHX58 | -0.0457533 |
| ZNF717 | -0.0457570 |
| TBX4 | -0.0457628 |
| GPR82 | -0.0457695 |
| EXPH5 | -0.0457748 |
| SYT10 | -0.0458180 |
| TNFRSF10D | -0.0458237 |
| LRRC38 | -0.0458318 |
| C10orf111 | -0.0458348 |
| PIP5K1C | -0.0458481 |
| TRPV1 | -0.0458692 |
| ATG12 | -0.0458714 |
| IL17B | -0.0458739 |
| INHA | -0.0458893 |
| USP36 | -0.0458927 |
| ZC3H14 | -0.0459106 |
| BCAS3 | -0.0459296 |
| ANKRD32 | -0.0459623 |
| REEP3 | -0.0459772 |
| TNFRSF11B | -0.0459804 |
| SDSL | -0.0459806 |
| ARMC8 | -0.0459927 |
| MYADM | -0.0460053 |
| GOLGA6L10 | -0.0460254 |
| MCF2 | -0.0460527 |
| COMMD4 | -0.0460692 |
| SMS | -0.0460713 |
| C22orf31 | -0.0460818 |
| CCM2L | -0.0460881 |
| LYZL6 | -0.0460985 |
| EBF2 | -0.0461048 |
| CDKL4 | -0.0461182 |
| MUT | -0.0461189 |
| UBR4 | -0.0461201 |
| FAM193B | -0.0461275 |
| APOB | -0.0461282 |
| VPS36 | -0.0461543 |
| BDH1 | -0.0461639 |
| FOXF2 | -0.0462118 |
| THOC2 | -0.0462204 |
| MBOAT4 | -0.0462244 |
| LY6G5B | -0.0462704 |
| TRIM42 | -0.0462720 |
| SCGB2A1 | -0.0462844 |
| PDZD4 | -0.0462923 |
| REG4 | -0.0462938 |
| KDR | -0.0462939 |
| ORMDL1 | -0.0463017 |
| CDH16 | -0.0463423 |
| MRPL50 | -0.0463497 |
| RLN3 | -0.0463505 |
| SRSF11 | -0.0463758 |
| TMC7 | -0.0463760 |
| CYP1A1 | -0.0463907 |
| ELP4 | -0.0463916 |
| C17orf99 | -0.0464005 |
| SAMD5 | -0.0464050 |
| AURKC | -0.0464107 |
| CELF5 | -0.0464132 |
| MBL2 | -0.0464366 |
| C7orf26 | -0.0464543 |
| EIF3I | -0.0464571 |
| FBXO25 | -0.0464792 |
| REG3G | -0.0464826 |
| LEPROTL1 | -0.0464844 |
| MT3 | -0.0464915 |
| CAMKK1 | -0.0465025 |
| AKAP4 | -0.0465042 |
| MYO1H | -0.0465196 |
| ELFN2 | -0.0465379 |
| INHBA | -0.0465382 |
| SLC41A1 | -0.0465386 |
| SMPD3 | -0.0465397 |
| TMEM27 | -0.0465427 |
| MYOC | -0.0465739 |
| DKFZP434A062 | -0.0465844 |
| TLK2 | -0.0465908 |
| CLTC | -0.0465995 |
| TBC1D8 | -0.0466090 |
| VPS13A | -0.0466126 |
| CEP152 | -0.0466393 |
| KCNS1 | -0.0466524 |
| KRTAP9-4 | -0.0466612 |
| DHX34 | -0.0466714 |
| POFUT2 | -0.0467154 |
| FAM209B | -0.0467203 |
| ADRB1 | -0.0467214 |
| VDAC1 | -0.0467260 |
| NARS | -0.0467306 |
| TRIM40 | -0.0467341 |
| ZNF583 | -0.0467378 |
| GAPT | -0.0467421 |
| WDR87 | -0.0467453 |
| FOXN1 | -0.0467667 |
| ITLN2 | -0.0467745 |
| HSD17B14 | -0.0467768 |
| KRT26 | -0.0468282 |
| COL5A2 | -0.0468333 |
| GALNT11 | -0.0468383 |
| IL4 | -0.0468579 |
| SEC24D | -0.0468637 |
| CEP170B | -0.0468694 |
| MUC7 | -0.0468901 |
| LMOD2 | -0.0468937 |
| SRP19 | -0.0469031 |
| C22orf24 | -0.0469085 |
| HS3ST2 | -0.0469126 |
| EIF4EBP2 | -0.0469268 |
| LYVE1 | -0.0469293 |
| WDR88 | -0.0469548 |
| SCN10A | -0.0469637 |
| ZNF600 | -0.0469692 |
| C11orf45 | -0.0469817 |
| PCDHB6 | -0.0469838 |
| OARD1 | -0.0469867 |
| SEC22C | -0.0469991 |
| LYG2 | -0.0470023 |
| CXCR1 | -0.0470243 |
| NDNL2 | -0.0470253 |
| KRT35 | -0.0470277 |
| REN | -0.0470388 |
| ANGPT2 | -0.0470439 |
| TGOLN2 | -0.0470499 |
| EMC1 | -0.0470564 |
| LARP4 | -0.0470894 |
| RXRG | -0.0471135 |
| HES6 | -0.0471184 |
| MCPH1 | -0.0471187 |
| FGFR1OP2 | -0.0471224 |
| CTCF | -0.0471245 |
| SLC5A12 | -0.0471246 |
| REEP4 | -0.0471424 |
| ZNF813 | -0.0471802 |
| GOLGA6A | -0.0471834 |
| CRCP | -0.0471860 |
| OIT3 | -0.0471966 |
| SFSWAP | -0.0472147 |
| SDK1 | -0.0472295 |
| ZNF668 | -0.0472383 |
| PRB2 | -0.0472403 |
| CTNNB1 | -0.0472424 |
| GC | -0.0472513 |
| C4orf33 | -0.0472531 |
| GPR62 | -0.0472591 |
| ONECUT1 | -0.0472608 |
| PAM | -0.0472784 |
| TPD52L3 | -0.0472885 |
| HTR3D | -0.0472938 |
| ACOX1 | -0.0472974 |
| PRNT | -0.0473027 |
| IQCD | -0.0473096 |
| ZSWIM8 | -0.0473101 |
| VAMP8 | -0.0473144 |
| ASTN2 | -0.0473235 |
| OR1L4 | -0.0473507 |
| RIOK3 | -0.0473519 |
| WBP1L | -0.0473552 |
| OR2T8 | -0.0473564 |
| SULT1E1 | -0.0473667 |
| SYNPO | -0.0473767 |
| TMEM255A | -0.0473823 |
| PDP2 | -0.0473878 |
| CDK18 | -0.0474137 |
| ZCWPW1 | -0.0474266 |
| KCNK10 | -0.0474361 |
| STK33 | -0.0474374 |
| NPM1 | -0.0474443 |
| WSCD2 | -0.0474451 |
| ELK3 | -0.0474503 |
| MFN2 | -0.0474738 |
| STAM2 | -0.0474881 |
| HDAC1 | -0.0474957 |
| OR51B4 | -0.0475043 |
| CYP11B2 | -0.0475095 |
| ZNF266 | -0.0475491 |
| ANKLE2 | -0.0475596 |
| MDS2 | -0.0475643 |
| LIG4 | -0.0475770 |
| SEMA6C | -0.0475849 |
| SMAD4 | -0.0476038 |
| CADM1 | -0.0476105 |
| UBE2U | -0.0476209 |
| OAZ2 | -0.0476421 |
| RNF187 | -0.0476462 |
| TRUB2 | -0.0476530 |
| C12orf79 | -0.0476603 |
| ERGIC2 | -0.0476698 |
| HIST1H2AA | -0.0476709 |
| PCDHGA2 | -0.0476736 |
| OR4C3 | -0.0476904 |
| GYS2 | -0.0477108 |
| IKZF4 | -0.0477364 |
| ZFP37 | -0.0477409 |
| ODF2L | -0.0477494 |
| HS6ST1 | -0.0477498 |
| HIPK3 | -0.0477604 |
| MARCH8 | -0.0477717 |
| C2orf70 | -0.0477729 |
| CAMSAP1 | -0.0477889 |
| CDHR5 | -0.0477933 |
| ABI3BP | -0.0478064 |
| COLQ | -0.0478191 |
| SHBG | -0.0478317 |
| SEPT7 | -0.0478357 |
| RFC1 | -0.0478395 |
| USP33 | -0.0478399 |
| MTUS2 | -0.0478410 |
| PRKAR2B | -0.0478475 |
| KCNAB3 | -0.0478641 |
| ERVFRD-1 | -0.0478727 |
| GALNT10 | -0.0478776 |
| RNASE7 | -0.0479013 |
| HTR4 | -0.0479022 |
| PRSS3 | -0.0479071 |
| BPIFA3 | -0.0479168 |
| SPTLC1 | -0.0479184 |
| STX12 | -0.0479224 |
| BMP15 | -0.0479244 |
| ZNF331 | -0.0479307 |
| VANGL1 | -0.0479310 |
| ZNF775 | -0.0479382 |
| SLC7A11 | -0.0479622 |
| ACSBG2 | -0.0479748 |
| CDNF | -0.0479820 |
| CUEDC2 | -0.0480133 |
| UMOD | -0.0480214 |
| NMUR2 | -0.0480355 |
| BTG2 | -0.0480382 |
| CTNNA3 | -0.0480416 |
| LRCH1 | -0.0480442 |
| CORO1B | -0.0480520 |
| ZSCAN4 | -0.0480614 |
| TUBE1 | -0.0480709 |
| TYRP1 | -0.0480791 |
| ZNF665 | -0.0480953 |
| PRPF38B | -0.0481063 |
| CPQ | -0.0481193 |
| ZSCAN20 | -0.0481340 |
| NINL | -0.0481552 |
| PPP4R1L | -0.0481572 |
| C9 | -0.0481624 |
| PPM1N | -0.0482234 |
| ZNF510 | -0.0482300 |
| GTF2E1 | -0.0482358 |
| ARMC1 | -0.0482384 |
| OCM2 | -0.0482538 |
| PLCZ1 | -0.0482599 |
| OR7D4 | -0.0482632 |
| ZXDA | -0.0482686 |
| C10orf62 | -0.0482764 |
| RHOXF2B | -0.0483015 |
| DFNB31 | -0.0483043 |
| LZIC | -0.0483382 |
| FUT6 | -0.0483449 |
| TSHB | -0.0483531 |
| NUFIP1 | -0.0483578 |
| UBL3 | -0.0483671 |
| MOSPD3 | -0.0483747 |
| DAO | -0.0484095 |
| MN1 | -0.0484137 |
| RAP2C | -0.0484170 |
| LEFTY2 | -0.0484264 |
| DEFA5 | -0.0484302 |
| ZBTB8A | -0.0484386 |
| TSHR | -0.0484420 |
| SMPD4 | -0.0484442 |
| PIGL | -0.0484464 |
| GYPB | -0.0484485 |
| ARRDC3 | -0.0484548 |
| WNT8A | -0.0484599 |
| ZBTB44 | -0.0484833 |
| P2RY1 | -0.0485235 |
| C11orf16 | -0.0485279 |
| MIP | -0.0485415 |
| DCP2 | -0.0485451 |
| USP42 | -0.0485476 |
| PIN4 | -0.0485554 |
| CFC1 | -0.0485868 |
| VWDE | -0.0485913 |
| G6PC2 | -0.0485991 |
| CCBL2 | -0.0486028 |
| NT5DC3 | -0.0486072 |
| TAC4 | -0.0486131 |
| SSMEM1 | -0.0486274 |
| RBM25 | -0.0486276 |
| CRY1 | -0.0486294 |
| CSF3 | -0.0486370 |
| A4GNT | -0.0486405 |
| MAP2 | -0.0486592 |
| B3GALT2 | -0.0486616 |
| RBMY1B | -0.0486635 |
| CCDC171 | -0.0486760 |
| C12orf42 | -0.0486874 |
| MRPS25 | -0.0486896 |
| CPN2 | -0.0486929 |
| CYP46A1 | -0.0487218 |
| DTHD1 | -0.0487242 |
| CREB3L4 | -0.0487371 |
| BEND6 | -0.0487395 |
| HSF2BP | -0.0487512 |
| DDB2 | -0.0487554 |
| ISLR2 | -0.0487625 |
| PPFIA2 | -0.0487699 |
| WT1 | -0.0487844 |
| SLC25A36 | -0.0487859 |
| KRT78 | -0.0487862 |
| WIZ | -0.0487864 |
| RBM4B | -0.0488036 |
| CNTN5 | -0.0488109 |
| HPS4 | -0.0488169 |
| HOXD4 | -0.0488283 |
| RBMXL2 | -0.0488401 |
| CARKD | -0.0488645 |
| HES2 | -0.0488680 |
| CLRN1 | -0.0488752 |
| PMS1 | -0.0489051 |
| TMEM196 | -0.0489154 |
| ZNF282 | -0.0489219 |
| KRTAP4-1 | -0.0489319 |
| CES5A | -0.0489330 |
| TFDP3 | -0.0489366 |
| PAIP2B | -0.0489416 |
| STXBP5L | -0.0489419 |
| UIMC1 | -0.0489667 |
| EFCAB11 | -0.0489706 |
| SLC22A7 | -0.0489748 |
| KCNA10 | -0.0489859 |
| SPRED2 | -0.0489883 |
| CCL22 | -0.0489978 |
| C9orf57 | -0.0490226 |
| FOXI1 | -0.0490314 |
| GMFB | -0.0490350 |
| KPNA6 | -0.0490415 |
| MAGEB4 | -0.0490497 |
| OR8D2 | -0.0490595 |
| TEDDM1 | -0.0490608 |
| ZNF57 | -0.0490932 |
| GLB1L3 | -0.0491124 |
| GPR149 | -0.0491139 |
| FOXJ3 | -0.0491178 |
| AVPR1A | -0.0491224 |
| PIWIL3 | -0.0491445 |
| LY6G5C | -0.0491517 |
| LHX4 | -0.0491680 |
| ERP44 | -0.0491695 |
| GABRA1 | -0.0491775 |
| FOXJ2 | -0.0491811 |
| RASSF3 | -0.0491819 |
| TXNDC15 | -0.0491846 |
| MRGPRX1 | -0.0491853 |
| WNK1 | -0.0491855 |
| TMEM186 | -0.0492100 |
| RIPPLY2 | -0.0492457 |
| CLVS1 | -0.0492537 |
| DLG2 | -0.0492604 |
| KCNQ5 | -0.0492649 |
| CT45A5 | -0.0492798 |
| VHLL | -0.0492913 |
| CALCOCO2 | -0.0493076 |
| MCOLN3 | -0.0493082 |
| SLC13A1 | -0.0493163 |
| MAP3K4 | -0.0493262 |
| ZC3H7B | -0.0493299 |
| DEFB126 | -0.0493377 |
| USH1G | -0.0493558 |
| SLC17A1 | -0.0493704 |
| ZKSCAN5 | -0.0493721 |
| OR5T2 | -0.0493967 |
| PPP6C | -0.0494042 |
| PPP1R12A | -0.0494056 |
| GOLGA8M | -0.0494082 |
| CPSF2 | -0.0494086 |
| LRRC19 | -0.0494204 |
| KCNA6 | -0.0494280 |
| PLD2 | -0.0494293 |
| FGF23 | -0.0494463 |
| EQTN | -0.0494479 |
| PTRH1 | -0.0494588 |
| GSC2 | -0.0494707 |
| LTN1 | -0.0494874 |
| NAGPA | -0.0494922 |
| FNDC4 | -0.0495146 |
| SEC14L5 | -0.0495193 |
| ASB12 | -0.0495236 |
| DARS2 | -0.0495526 |
| IRF6 | -0.0495784 |
| PRR7 | -0.0495844 |
| TARSL2 | -0.0496049 |
| LRFN4 | -0.0496097 |
| HNF1A | -0.0496367 |
| TP73 | -0.0496400 |
| CCDC62 | -0.0496492 |
| LIPT1 | -0.0496521 |
| OR12D3 | -0.0496600 |
| C3orf20 | -0.0496639 |
| COL8A2 | -0.0496642 |
| ELK1 | -0.0496706 |
| ASB7 | -0.0496989 |
| TMUB2 | -0.0496996 |
| IFNA16 | -0.0497135 |
| FSD2 | -0.0497312 |
| NRDE2 | -0.0497368 |
| ACOT12 | -0.0497386 |
| C4orf29 | -0.0497443 |
| B3GAT3 | -0.0497539 |
| ELAVL2 | -0.0497735 |
| PGM5 | -0.0497973 |
| BHMT | -0.0498145 |
| C11orf54 | -0.0498430 |
| GAL3ST2 | -0.0498808 |
| AOC1 | -0.0498870 |
| COLEC10 | -0.0498923 |
| PRPF6 | -0.0499437 |
| VGLL2 | -0.0499794 |
| CEP70 | -0.0499844 |
| COL19A1 | -0.0499847 |
| VENTX | -0.0499853 |
| HTR1E | -0.0499878 |
| RABEPK | -0.0499893 |
| TRPC4 | -0.0499935 |
| MRC2 | -0.0500060 |
| TYR | -0.0500077 |
| MBD1 | -0.0500137 |
| CDH9 | -0.0500171 |
| PTGES3 | -0.0500349 |
| B4GALNT1 | -0.0500480 |
| PID1 | -0.0500548 |
| FBXW11 | -0.0500561 |
| GPR55 | -0.0500627 |
| ARFGAP1 | -0.0500630 |
| IGLON5 | -0.0500666 |
| GLRA4 | -0.0500827 |
| GAGE1 | -0.0500901 |
| NR1H4 | -0.0500923 |
| GLRA2 | -0.0501034 |
| TAS2R1 | -0.0501054 |
| ZNF426 | -0.0501125 |
| PRICKLE4 | -0.0501125 |
| NLRP10 | -0.0501450 |
| STARD6 | -0.0501582 |
| BCCIP | -0.0501669 |
| MMD2 | -0.0501742 |
| ZNF385A | -0.0501796 |
| TRIM15 | -0.0501871 |
| PIN1 | -0.0501887 |
| PGS1 | -0.0501910 |
| ZFAND2A | -0.0502047 |
| AKT3 | -0.0502203 |
| DNMT3L | -0.0502317 |
| RGPD5 | -0.0502380 |
| C20orf173 | -0.0502387 |
| MESDC2 | -0.0502512 |
| FAM175B | -0.0502815 |
| RNF39 | -0.0503201 |
| WDR48 | -0.0503385 |
| TLN2 | -0.0503420 |
| SNX2 | -0.0503430 |
| CNTN6 | -0.0503431 |
| XAGE5 | -0.0503492 |
| FAM131B | -0.0503590 |
| WDR26 | -0.0503612 |
| SIM2 | -0.0503760 |
| OR2C1 | -0.0503761 |
| RAD52 | -0.0503831 |
| NCKIPSD | -0.0504084 |
| POU3F2 | -0.0504186 |
| OR51B2 | -0.0504190 |
| TRPM1 | -0.0504283 |
| XPO7 | -0.0504299 |
| HSPA13 | -0.0504375 |
| SDC2 | -0.0504702 |
| MSH4 | -0.0504706 |
| CUTA | -0.0504848 |
| MED14 | -0.0504990 |
| CHL1 | -0.0505002 |
| CNPY2 | -0.0505125 |
| ZNF354A | -0.0505214 |
| CUX2 | -0.0505436 |
| SPATA31A3 | -0.0505634 |
| SCRT1 | -0.0506041 |
| SLC22A11 | -0.0506080 |
| TRERF1 | -0.0506104 |
| ZNF644 | -0.0506319 |
| FOXK1 | -0.0506464 |
| PTPN18 | -0.0506466 |
| GOSR2 | -0.0506516 |
| KRT25 | -0.0506669 |
| GALNT13 | -0.0506751 |
| KRT77 | -0.0506905 |
| PAQR7 | -0.0507049 |
| MTCP1 | -0.0507057 |
| SBNO1 | -0.0507221 |
| PRAMEF16 | -0.0507238 |
| LONRF1 | -0.0507526 |
| GPR61 | -0.0507562 |
| SLC30A10 | -0.0507634 |
| C7orf33 | -0.0507640 |
| LAPTM4A | -0.0507874 |
| OR4C46 | -0.0507937 |
| RNF34 | -0.0507952 |
| RNF216 | -0.0508084 |
| TACR1 | -0.0508126 |
| FIBIN | -0.0508370 |
| CLEC2L | -0.0508382 |
| ANGPT4 | -0.0508535 |
| RPP14 | -0.0508540 |
| KIR3DL3 | -0.0508749 |
| PAQR6 | -0.0508783 |
| HCFC1 | -0.0508874 |
| HSBP1 | -0.0508893 |
| ELAVL4 | -0.0508958 |
| WFIKKN2 | -0.0509004 |
| MCTS1 | -0.0509060 |
| ANKRD36 | -0.0509348 |
| GUCY2D | -0.0509376 |
| PLEKHM3 | -0.0509412 |
| DYNAP | -0.0509573 |
| SEMA4B | -0.0509803 |
| CDH23 | -0.0509870 |
| GLS | -0.0510042 |
| SP1 | -0.0510079 |
| THAP4 | -0.0510189 |
| HIST1H2AE | -0.0510486 |
| ZFY | -0.0510530 |
| TNFAIP6 | -0.0510751 |
| RABIF | -0.0510791 |
| PCDHGA9 | -0.0510814 |
| MARCH2 | -0.0510870 |
| DDX50 | -0.0510876 |
| LELP1 | -0.0510908 |
| ASB11 | -0.0511050 |
| SLC20A2 | -0.0511168 |
| CORO2B | -0.0511364 |
| CTRC | -0.0511584 |
| ATG10 | -0.0511707 |
| ZNF77 | -0.0511710 |
| HNRNPU | -0.0511789 |
| KLK15 | -0.0511800 |
| ZNF227 | -0.0512027 |
| ACO1 | -0.0512175 |
| GPR123 | -0.0512176 |
| SPOP | -0.0512400 |
| WDR44 | -0.0512439 |
| SEMA3E | -0.0512631 |
| INSL6 | -0.0512661 |
| MASP2 | -0.0512703 |
| VN1R4 | -0.0512721 |
| ING2 | -0.0512759 |
| ZNF512 | -0.0512861 |
| DGCR6L | -0.0513057 |
| TLK1 | -0.0513143 |
| VCPKMT | -0.0513161 |
| CCDC70 | -0.0513288 |
| CC2D2B | -0.0513401 |
| EFEMP2 | -0.0513645 |
| ERVMER34-1 | -0.0513648 |
| KIF13A | -0.0513700 |
| FAM150A | -0.0513837 |
| RPS2 | -0.0513895 |
| ROS1 | -0.0513922 |
| C2CD3 | -0.0514280 |
| PROC | -0.0514336 |
| MAGEA11 | -0.0514413 |
| ZCCHC2 | -0.0514661 |
| SMIM12 | -0.0514683 |
| GNA11 | -0.0514857 |
| LCE1F | -0.0514869 |
| ILK | -0.0514975 |
| SIPA1L3 | -0.0514997 |
| YBEY | -0.0515036 |
| CFHR1 | -0.0515067 |
| TRAPPC11 | -0.0515148 |
| ZFAND6 | -0.0515169 |
| NEFH | -0.0515289 |
| C15orf37 | -0.0515394 |
| TGM3 | -0.0515428 |
| ATP12A | -0.0515448 |
| FAM71D | -0.0515500 |
| ZCCHC14 | -0.0515509 |
| MYH6 | -0.0515699 |
| GRID2 | -0.0515841 |
| IFI27L2 | -0.0515882 |
| CDH8 | -0.0515904 |
| GUCA1C | -0.0515937 |
| OR2A14 | -0.0515976 |
| ATP6V1E2 | -0.0516113 |
| DNAJC1 | -0.0516182 |
| MAN1A2 | -0.0516249 |
| DNAJA2 | -0.0516401 |
| ZNF841 | -0.0516693 |
| KIF3C | -0.0516702 |
| MYLK2 | -0.0516777 |
| RDH16 | -0.0516841 |
| C11orf87 | -0.0516842 |
| VCPIP1 | -0.0516957 |
| NEU3 | -0.0517185 |
| SH2D6 | -0.0517258 |
| EYS | -0.0517658 |
| DMAP1 | -0.0517669 |
| C11orf63 | -0.0517777 |
| ELMO2 | -0.0518097 |
| NF1 | -0.0518097 |
| PSPN | -0.0518526 |
| ADIPOR1 | -0.0518595 |
| ATP8B2 | -0.0518803 |
| ISCU | -0.0519053 |
| HIST1H2BA | -0.0519144 |
| STX1A | -0.0519148 |
| KRTAP1-1 | -0.0519180 |
| IRAK1BP1 | -0.0519210 |
| MAP1B | -0.0519224 |
| SUPT3H | -0.0519316 |
| TRAK1 | -0.0519433 |
| ERMN | -0.0519455 |
| WNT3A | -0.0519553 |
| PHLPP1 | -0.0519586 |
| RRP9 | -0.0519831 |
| EXD2 | -0.0519834 |
| CLPSL2 | -0.0519897 |
| HEXDC | -0.0520190 |
| SLC7A14 | -0.0520219 |
| CTSE | -0.0520365 |
| DCAF15 | -0.0520479 |
| RBM17 | -0.0520511 |
| GRXCR1 | -0.0520763 |
| EIF3A | -0.0520859 |
| PEMT | -0.0521058 |
| TSLP | -0.0521338 |
| PKD2L2 | -0.0521345 |
| CAMTA1 | -0.0521500 |
| FAM83C | -0.0521551 |
| BTBD7 | -0.0521688 |
| SLC12A6 | -0.0521725 |
| DPPA4 | -0.0521777 |
| RC3H1 | -0.0521912 |
| FGF16 | -0.0522129 |
| GGN | -0.0522148 |
| RAC1 | -0.0522320 |
| TGFB1I1 | -0.0522436 |
| PANK3 | -0.0522634 |
| CALN1 | -0.0522916 |
| KCNE1 | -0.0523018 |
| SCARA3 | -0.0523182 |
| SLC26A2 | -0.0523193 |
| KCNA7 | -0.0523344 |
| HIF1AN | -0.0523725 |
| CASP9 | -0.0523793 |
| NHLH1 | -0.0523840 |
| STIM2 | -0.0523910 |
| TEX36 | -0.0524079 |
| C19orf25 | -0.0524255 |
| RNF135 | -0.0524273 |
| ATP2B4 | -0.0524456 |
| PET112 | -0.0524690 |
| NPSR1 | -0.0524918 |
| SLC16A12 | -0.0524957 |
| AZIN1 | -0.0524990 |
| WWC1 | -0.0525135 |
| NXPE3 | -0.0525259 |
| IQCF5 | -0.0525269 |
| DEFB4A | -0.0525398 |
| LUC7L2 | -0.0525414 |
| ABCB11 | -0.0525420 |
| COG3 | -0.0525503 |
| TMEM231 | -0.0525720 |
| KLK2 | -0.0525807 |
| ART1 | -0.0525852 |
| MYLK3 | -0.0525944 |
| CCDC102B | -0.0526099 |
| GLTSCR1L | -0.0526235 |
| SPTB | -0.0526242 |
| IPO9 | -0.0526393 |
| TSPY4 | -0.0526798 |
| GPR20 | -0.0526818 |
| ESF1 | -0.0526924 |
| USP38 | -0.0526946 |
| NOTCH2NL | -0.0527083 |
| DEFA6 | -0.0527098 |
| IRAK4 | -0.0527103 |
| ANAPC7 | -0.0527271 |
| OTOL1 | -0.0527323 |
| ABHD12 | -0.0527341 |
| MEF2A | -0.0527344 |
| GBX1 | -0.0527415 |
| PSMD9 | -0.0527480 |
| PRDM14 | -0.0527541 |
| AMELY | -0.0527584 |
| TENM3 | -0.0527710 |
| SLC6A3 | -0.0527993 |
| TUBB1 | -0.0528084 |
| REG3A | -0.0528216 |
| KDM5B | -0.0528245 |
| PRDM4 | -0.0528269 |
| C21orf62 | -0.0528284 |
| BIK | -0.0528323 |
| AZI2 | -0.0528447 |
| TSPAN5 | -0.0528468 |
| C2orf42 | -0.0528479 |
| ALKBH8 | -0.0528527 |
| CPEB4 | -0.0528533 |
| TTLL5 | -0.0528568 |
| PRSS42 | -0.0528613 |
| KIDINS220 | -0.0528683 |
| DMC1 | -0.0528694 |
| FRG1 | -0.0528729 |
| C14orf178 | -0.0528746 |
| UBR7 | -0.0528849 |
| NKPD1 | -0.0528852 |
| SOBP | -0.0528890 |
| PRX | -0.0529094 |
| EP400 | -0.0529114 |
| LRP11 | -0.0529160 |
| BCL2L1 | -0.0529488 |
| GAPDHS | -0.0529503 |
| PRRC1 | -0.0529547 |
| PSMC3IP | -0.0529630 |
| PCCA | -0.0529891 |
| GABRG3 | -0.0530021 |
| OR2S2 | -0.0530095 |
| KCNB1 | -0.0530357 |
| ALDOB | -0.0530470 |
| ADAMTS12 | -0.0530536 |
| RNF128 | -0.0530566 |
| PDE1B | -0.0530580 |
| SSX5 | -0.0530742 |
| LDB3 | -0.0530785 |
| HIST1H1E | -0.0530852 |
| C15orf61 | -0.0530973 |
| EMC7 | -0.0530991 |
| TTYH2 | -0.0531097 |
| SIK2 | -0.0531120 |
| NPR2 | -0.0531126 |
| RCVRN | -0.0531175 |
| RETSAT | -0.0531218 |
| SOHLH2 | -0.0531345 |
| SOWAHC | -0.0531405 |
| CTSO | -0.0531429 |
| SH3D21 | -0.0531455 |
| TINAG | -0.0531492 |
| HMCN2 | -0.0531497 |
| ZAR1 | -0.0531616 |
| LTBP2 | -0.0531644 |
| RGS6 | -0.0531671 |
| AP1S3 | -0.0531684 |
| USP45 | -0.0531908 |
| PODNL1 | -0.0532262 |
| NFXL1 | -0.0532511 |
| PCSK5 | -0.0532607 |
| LPAR4 | -0.0532699 |
| ST3GAL4 | -0.0532947 |
| RNF2 | -0.0532994 |
| SRCRB4D | -0.0533026 |
| KCNH1 | -0.0533270 |
| NOX4 | -0.0533517 |
| CAPN15 | -0.0533521 |
| TMTC1 | -0.0533541 |
| PTH | -0.0533726 |
| PRDM10 | -0.0533897 |
| CES3 | -0.0534347 |
| STK32A | -0.0534370 |
| TAS2R39 | -0.0534392 |
| PRR16 | -0.0534424 |
| YIPF7 | -0.0534706 |
| KAAG1 | -0.0534825 |
| PM20D1 | -0.0534846 |
| EDC3 | -0.0534888 |
| TRPM3 | -0.0535092 |
| PROK2 | -0.0535201 |
| PKD1 | -0.0535285 |
| XIRP2 | -0.0535311 |
| PHYHIPL | -0.0535366 |
| CD22 | -0.0535370 |
| KCNJ4 | -0.0535392 |
| CPLX4 | -0.0535440 |
| AVPI1 | -0.0535695 |
| RS1 | -0.0535757 |
| MAGEA8 | -0.0535881 |
| NT5C1A | -0.0535921 |
| BOLL | -0.0536208 |
| RBAK-RBAKDN | -0.0536349 |
| ACAD10 | -0.0536358 |
| CCDC94 | -0.0536364 |
| HEPN1 | -0.0536384 |
| GORASP1 | -0.0536388 |
| PCED1A | -0.0536391 |
| RCOR1 | -0.0536487 |
| SF1 | -0.0536499 |
| SLC38A1 | -0.0536523 |
| RESP18 | -0.0536527 |
| ADAMTSL3 | -0.0536530 |
| DVL1 | -0.0536727 |
| GSS | -0.0536760 |
| CYP51A1 | -0.0536781 |
| ARHGEF35 | -0.0537068 |
| ATP6V1D | -0.0537418 |
| ENC1 | -0.0537437 |
| SPAM1 | -0.0537451 |
| SPATS1 | -0.0537586 |
| SPEM1 | -0.0537595 |
| RAB6B | -0.0537710 |
| PDE1C | -0.0537752 |
| APOA1 | -0.0537756 |
| FAM71F1 | -0.0537853 |
| AKAP10 | -0.0537959 |
| GCGR | -0.0537981 |
| OR12D2 | -0.0538162 |
| TM4SF19 | -0.0538194 |
| CBWD2 | -0.0538369 |
| PRSS58 | -0.0538389 |
| TPCN2 | -0.0538435 |
| COPZ1 | -0.0538483 |
| KCNH7 | -0.0538498 |
| ZCCHC12 | -0.0538548 |
| LYPD8 | -0.0538600 |
| FAM220A | -0.0538667 |
| CCT8L2 | -0.0539295 |
| CD93 | -0.0539424 |
| KDM6B | -0.0539506 |
| GOLGA7 | -0.0539604 |
| GNL1 | -0.0539664 |
| CCDC27 | -0.0539705 |
| OMP | -0.0539842 |
| SNX31 | -0.0539884 |
| MAP1LC3C | -0.0540074 |
| ARL4A | -0.0540098 |
| CLYBL | -0.0540179 |
| YIF1B | -0.0540193 |
| USP13 | -0.0540304 |
| PSORS1C1 | -0.0540489 |
| GABBR1 | -0.0540871 |
| THG1L | -0.0541109 |
| OR11H12 | -0.0541127 |
| NMRK2 | -0.0541134 |
| MIDN | -0.0541170 |
| EXOG | -0.0541219 |
| KRTAP4-7 | -0.0541235 |
| RHD | -0.0541365 |
| PPIL3 | -0.0541548 |
| STRAP | -0.0541625 |
| ANXA10 | -0.0541794 |
| C11orf44 | -0.0541895 |
| RNF17 | -0.0541968 |
| KIAA0753 | -0.0542200 |
| NR4A1 | -0.0542628 |
| DXO | -0.0542688 |
| TOX3 | -0.0542801 |
| SNAPC3 | -0.0543063 |
| AMBRA1 | -0.0543142 |
| TAS2R3 | -0.0543232 |
| CALM1 | -0.0543518 |
| HIST1H4I | -0.0543528 |
| STK16 | -0.0543687 |
| TRPM6 | -0.0543702 |
| ZNF804A | -0.0543899 |
| C1orf216 | -0.0544014 |
| SLC25A46 | -0.0544068 |
| CLNS1A | -0.0544205 |
| RNF169 | -0.0544334 |
| MLNR | -0.0544353 |
| TMEM57 | -0.0544367 |
| RAD21L1 | -0.0544514 |
| KLHL14 | -0.0544604 |
| CPB2 | -0.0544751 |
| MBP | -0.0544758 |
| CATSPERG | -0.0544760 |
| MRGPRX2 | -0.0544866 |
| GRM2 | -0.0545059 |
| SPEG | -0.0545363 |
| TUBA8 | -0.0545378 |
| PHYH | -0.0545408 |
| HTN3 | -0.0545415 |
| MC3R | -0.0545548 |
| ZNF654 | -0.0545659 |
| ZNF829 | -0.0545793 |
| PKN1 | -0.0545863 |
| SAYSD1 | -0.0546200 |
| PHF10 | -0.0546320 |
| SLC25A31 | -0.0546537 |
| GPR125 | -0.0546604 |
| HOXB1 | -0.0546689 |
| HOXD9 | -0.0546812 |
| POLR2J | -0.0546918 |
| FUBP3 | -0.0546949 |
| BCOR | -0.0547000 |
| FNTB | -0.0547023 |
| CYFIP1 | -0.0547027 |
| BCL6 | -0.0547210 |
| TSSK3 | -0.0547338 |
| ZDHHC21 | -0.0547385 |
| IL23R | -0.0547454 |
| SYT6 | -0.0547512 |
| C10orf53 | -0.0547753 |
| PGLYRP1 | -0.0547836 |
| F3 | -0.0547870 |
| DLX5 | -0.0547894 |
| KRTAP4-8 | -0.0548033 |
| CRYGB | -0.0548296 |
| ADAM29 | -0.0548335 |
| OR2M2 | -0.0548379 |
| PDX1 | -0.0548876 |
| SLC17A2 | -0.0548910 |
| COBL | -0.0548999 |
| CCIN | -0.0549081 |
| BPIFC | -0.0549110 |
| ALPL | -0.0549204 |
| C16orf92 | -0.0549255 |
| OR3A1 | -0.0549422 |
| IGFBP7 | -0.0549525 |
| SLAIN2 | -0.0549569 |
| CACNG7 | -0.0549569 |
| CYP26B1 | -0.0549676 |
| ATP2A1 | -0.0549751 |
| DCC | -0.0549777 |
| TAS2R19 | -0.0549822 |
| GP5 | -0.0550082 |
| DLGAP2 | -0.0550357 |
| PDXDC1 | -0.0550542 |
| ZYG11B | -0.0550631 |
| NR1D2 | -0.0550639 |
| SMAD7 | -0.0550677 |
| ZNF589 | -0.0550704 |
| HCG27 | -0.0550728 |
| PHOX2B | -0.0550839 |
| SDR9C7 | -0.0550877 |
| NUFIP2 | -0.0550923 |
| C9orf129 | -0.0550928 |
| TEX13A | -0.0551064 |
| CETN1 | -0.0551216 |
| TSSK6 | -0.0551226 |
| MYL2 | -0.0551436 |
| ALG11 | -0.0551478 |
| HTR2C | -0.0551626 |
| N6AMT2 | -0.0551647 |
| LMOD1 | -0.0551711 |
| ETV1 | -0.0551809 |
| SCRN1 | -0.0551817 |
| PRAMEF8 | -0.0551824 |
| C7orf69 | -0.0551848 |
| SNX33 | -0.0551867 |
| EPB41 | -0.0552155 |
| IFNA2 | -0.0552255 |
| FRMPD1 | -0.0552475 |
| UNK | -0.0552517 |
| MTERFD2 | -0.0552628 |
| IARS2 | -0.0552631 |
| GRM7 | -0.0552815 |
| MRPL34 | -0.0553072 |
| RNF146 | -0.0553369 |
| IFITM2 | -0.0553373 |
| GCKR | -0.0553386 |
| TRIML1 | -0.0553443 |
| CYP19A1 | -0.0553605 |
| WDR11 | -0.0553618 |
| PLEKHA1 | -0.0553756 |
| PRR18 | -0.0553784 |
| ZNF585B | -0.0553789 |
| DNAJC27 | -0.0553862 |
| CPNE9 | -0.0553945 |
| LLGL2 | -0.0553950 |
| ZNF284 | -0.0553962 |
| TREML4 | -0.0553976 |
| C6orf10 | -0.0553999 |
| RAB18 | -0.0554041 |
| OLIG2 | -0.0554151 |
| ZNF230 | -0.0554200 |
| SERPINE1 | -0.0554231 |
| COL5A1 | -0.0554388 |
| SOX1 | -0.0554474 |
| MCMDC2 | -0.0554500 |
| OSBPL10 | -0.0554638 |
| GAB1 | -0.0554732 |
| RAB34 | -0.0554757 |
| C19orf53 | -0.0555037 |
| F10 | -0.0555043 |
| OSBPL9 | -0.0555151 |
| GUSB | -0.0555242 |
| CEND1 | -0.0555539 |
| OSBP2 | -0.0555594 |
| RBPJL | -0.0556025 |
| MPP4 | -0.0556243 |
| PATE1 | -0.0556396 |
| TRIM62 | -0.0556400 |
| MKKS | -0.0556412 |
| METTL18 | -0.0556417 |
| ZNF682 | -0.0556603 |
| CTF1 | -0.0556637 |
| OCLM | -0.0556663 |
| DDX51 | -0.0556758 |
| IPO7 | -0.0556779 |
| DNAJB1 | -0.0556816 |
| BSCL2 | -0.0556945 |
| SPO11 | -0.0557147 |
| STATH | -0.0557182 |
| MLN | -0.0557206 |
| ZNF23 | -0.0557333 |
| LRRC1 | -0.0557424 |
| WFDC12 | -0.0557590 |
| TNPO2 | -0.0557605 |
| SEPT4 | -0.0557767 |
| LPAR1 | -0.0557879 |
| THRA | -0.0557972 |
| SSX2IP | -0.0558507 |
| ACVR1B | -0.0558589 |
| KNCN | -0.0558602 |
| PHLDB2 | -0.0558604 |
| SLC4A3 | -0.0558729 |
| GTF2F1 | -0.0558743 |
| PCDHAC1 | -0.0558818 |
| CCDC42 | -0.0558914 |
| HIBCH | -0.0558948 |
| PRPSAP1 | -0.0558969 |
| PPEF1 | -0.0559326 |
| HAPLN4 | -0.0559403 |
| LAMTOR5 | -0.0559486 |
| TWIST1 | -0.0559571 |
| PRAMEF2 | -0.0559636 |
| ZNF320 | -0.0559698 |
| ZNF780B | -0.0559800 |
| QRICH1 | -0.0559885 |
| B3GALT1 | -0.0559939 |
| ABCB6 | -0.0559969 |
| TMC3 | -0.0559980 |
| MS4A3 | -0.0560035 |
| APLP1 | -0.0560058 |
| ATF2 | -0.0560243 |
| SIX6 | -0.0560283 |
| PXT1 | -0.0560355 |
| C3orf17 | -0.0560434 |
| UGT2B17 | -0.0560534 |
| SLC22A9 | -0.0560630 |
| RFT1 | -0.0560637 |
| PTH2R | -0.0560654 |
| NSMCE2 | -0.0560794 |
| CCDC112 | -0.0560901 |
| SOX15 | -0.0560967 |
| IMPAD1 | -0.0561090 |
| CNBD1 | -0.0561130 |
| ELP3 | -0.0561172 |
| DDIT3 | -0.0561278 |
| RPL31 | -0.0561357 |
| KIAA2018 | -0.0561595 |
| FAM133B | -0.0561679 |
| TTC7B | -0.0561778 |
| CBFA2T2 | -0.0561831 |
| TAS2R40 | -0.0561897 |
| CRYBB1 | -0.0562381 |
| TAAR6 | -0.0562412 |
| SLC35G3 | -0.0562498 |
| PRSS53 | -0.0562540 |
| FIZ1 | -0.0562552 |
| FAM27E2 | -0.0562553 |
| B3GAT2 | -0.0562590 |
| KCNJ9 | -0.0562716 |
| IFNE | -0.0562726 |
| CCDC88C | -0.0562804 |
| PATZ1 | -0.0562856 |
| AKAP17A | -0.0562913 |
| CDYL2 | -0.0563139 |
| APOA4 | -0.0563145 |
| PRAMEF1 | -0.0563200 |
| CERS5 | -0.0563286 |
| DCTN2 | -0.0563489 |
| SCN11A | -0.0563594 |
| ARL6 | -0.0563677 |
| SH3BP4 | -0.0563738 |
| PSG8 | -0.0563858 |
| EPC2 | -0.0563866 |
| CHRND | -0.0564016 |
| VEGFB | -0.0564145 |
| RPH3A | -0.0564198 |
| STOML3 | -0.0564229 |
| MEOX1 | -0.0564430 |
| QTRT1 | -0.0564501 |
| RBBP9 | -0.0564710 |
| MSRB2 | -0.0564913 |
| TTL | -0.0564944 |
| TSFM | -0.0564972 |
| OR56B1 | -0.0565174 |
| GPR101 | -0.0565225 |
| TUB | -0.0565314 |
| DOC2B | -0.0565332 |
| BRINP1 | -0.0565386 |
| UPK3A | -0.0565495 |
| ZBTB2 | -0.0565558 |
| PAPPA | -0.0565780 |
| FNTA | -0.0565870 |
| KCNG2 | -0.0566256 |
| WFDC10A | -0.0566390 |
| TRIM48 | -0.0566694 |
| EHHADH | -0.0566715 |
| CRP | -0.0566782 |
| DSC3 | -0.0566834 |
| PCDH18 | -0.0566869 |
| TBC1D17 | -0.0566881 |
| ARL2BP | -0.0567144 |
| ASZ1 | -0.0567281 |
| TENM4 | -0.0567328 |
| MEGF10 | -0.0567403 |
| TM7SF3 | -0.0567655 |
| MRPL43 | -0.0567672 |
| VPS53 | -0.0567701 |
| SPAG11B | -0.0567707 |
| MMP8 | -0.0567763 |
| SLC25A2 | -0.0567816 |
| TNKS1BP1 | -0.0567842 |
| FAM154A | -0.0567904 |
| KIAA1524 | -0.0567904 |
| CYLC1 | -0.0567944 |
| SRGAP2 | -0.0568275 |
| PADI4 | -0.0568302 |
| LUZP4 | -0.0568308 |
| HOXC11 | -0.0568351 |
| SLIT1 | -0.0568470 |
| OR8K3 | -0.0568776 |
| TMPRSS12 | -0.0568797 |
| XPR1 | -0.0568957 |
| IRGC | -0.0569154 |
| COQ10B | -0.0569316 |
| SIAH3 | -0.0569569 |
| GABRG1 | -0.0569679 |
| KCNIP2 | -0.0570111 |
| GCLC | -0.0570263 |
| CLDN22 | -0.0570468 |
| C5AR2 | -0.0570498 |
| PDCL2 | -0.0570970 |
| PIGR | -0.0571091 |
| C19orf26 | -0.0571239 |
| NMT1 | -0.0571320 |
| RHOXF2 | -0.0571364 |
| CACNA1I | -0.0571372 |
| GLRA1 | -0.0571514 |
| TTC23 | -0.0571562 |
| FAM24A | -0.0571840 |
| ADH5 | -0.0571848 |
| IL3 | -0.0571958 |
| EMC2 | -0.0572017 |
| GRIPAP1 | -0.0572068 |
| RARA | -0.0572299 |
| KCNS2 | -0.0572308 |
| VPRBP | -0.0572412 |
| GALNT8 | -0.0572535 |
| SLC18A1 | -0.0572827 |
| BRF1 | -0.0573039 |
| HIST1H4G | -0.0573062 |
| OR2L13 | -0.0573133 |
| SEC14L3 | -0.0573280 |
| PDCD7 | -0.0573295 |
| TENM1 | -0.0573302 |
| TBC1D29 | -0.0573338 |
| NXPE2 | -0.0573372 |
| FBXW8 | -0.0573623 |
| FAM215A | -0.0573643 |
| GABARAPL3 | -0.0573819 |
| SLC25A26 | -0.0573837 |
| RPL37A | -0.0574135 |
| PHKA2 | -0.0574184 |
| HSD17B13 | -0.0574468 |
| MLEC | -0.0574529 |
| LBX2 | -0.0574696 |
| ARL4D | -0.0574795 |
| SNURF | -0.0574817 |
| LGALS13 | -0.0574938 |
| LRRC58 | -0.0574990 |
| LHX9 | -0.0575022 |
| HPS3 | -0.0575033 |
| PROS1 | -0.0575206 |
| SLC26A1 | -0.0575239 |
| AP2A2 | -0.0575332 |
| ATP5SL | -0.0575395 |
| KLHL17 | -0.0575454 |
| MMRN2 | -0.0575589 |
| ACOT11 | -0.0575592 |
| CHRNA6 | -0.0575845 |
| PEX16 | -0.0576094 |
| TP53RK | -0.0576122 |
| ABCB4 | -0.0576184 |
| CASR | -0.0576262 |
| ICK | -0.0576319 |
| NUPR1L | -0.0576712 |
| CSMD2 | -0.0576925 |
| LRRN4 | -0.0576928 |
| DIS3 | -0.0576980 |
| RNF6 | -0.0577007 |
| CWC27 | -0.0577015 |
| MOGAT2 | -0.0577065 |
| B3GALT5 | -0.0577069 |
| TAS2R38 | -0.0577124 |
| KIR3DX1 | -0.0577251 |
| ASUN | -0.0577295 |
| CARD18 | -0.0577764 |
| PI16 | -0.0577792 |
| POU1F1 | -0.0577908 |
| NXF2 | -0.0577986 |
| CRX | -0.0578357 |
| FOXE3 | -0.0578395 |
| TRIM55 | -0.0578480 |
| MYO5B | -0.0578621 |
| APOBEC1 | -0.0578630 |
| ZNF26 | -0.0578748 |
| TEC | -0.0578835 |
| USP2 | -0.0578888 |
| FAM76A | -0.0578998 |
| TSEN2 | -0.0579223 |
| GPX6 | -0.0579341 |
| RIT2 | -0.0579559 |
| BUB3 | -0.0579581 |
| PEX14 | -0.0579884 |
| TAS2R8 | -0.0580085 |
| PDZRN3 | -0.0580180 |
| C1orf127 | -0.0580195 |
| SPTBN1 | -0.0580337 |
| TBC1D24 | -0.0580361 |
| LARP7 | -0.0580403 |
| AASDH | -0.0580479 |
| TMEM241 | -0.0580523 |
| GPR21 | -0.0581099 |
| LRAT | -0.0581148 |
| KIF6 | -0.0581304 |
| HTR2A | -0.0581312 |
| KIF26B | -0.0581361 |
| SERPINE3 | -0.0581362 |
| SRCAP | -0.0581463 |
| BPIFB4 | -0.0581486 |
| IQCG | -0.0581525 |
| HES1 | -0.0581590 |
| BLCAP | -0.0581599 |
| CLEC18A | -0.0581643 |
| H2AFY | -0.0581859 |
| MAPK9 | -0.0581912 |
| ARHGEF16 | -0.0581962 |
| C3orf14 | -0.0581965 |
| ADH4 | -0.0582095 |
| PLEKHA7 | -0.0582125 |
| TGM5 | -0.0582242 |
| PJA1 | -0.0582381 |
| OTOR | -0.0582597 |
| CHN2 | -0.0582633 |
| USH1C | -0.0582742 |
| SPTAN1 | -0.0582966 |
| TMEM184C | -0.0583260 |
| FOXO4 | -0.0583448 |
| RPS26 | -0.0583479 |
| C14orf183 | -0.0583502 |
| CACNA1C | -0.0583529 |
| ZSWIM2 | -0.0584114 |
| ADAMTS9 | -0.0584159 |
| ARHGAP1 | -0.0584255 |
| LGALS14 | -0.0584265 |
| BRSK2 | -0.0584389 |
| PYY | -0.0584537 |
| NOSIP | -0.0584637 |
| WNT5A | -0.0584657 |
| MYSM1 | -0.0584662 |
| SMCP | -0.0584770 |
| ZNF408 | -0.0584803 |
| C1orf87 | -0.0584843 |
| ACTL7B | -0.0584947 |
| FBXO24 | -0.0584974 |
| APOC3 | -0.0585069 |
| MUC17 | -0.0585142 |
| FAM153C | -0.0585198 |
| FAM65C | -0.0585253 |
| HINT1 | -0.0585273 |
| LYPD4 | -0.0585281 |
| RAB7A | -0.0585388 |
| GOSR1 | -0.0585453 |
| HABP2 | -0.0585698 |
| RBFOX1 | -0.0585816 |
| ENKUR | -0.0585961 |
| TRMT61B | -0.0586057 |
| PARP11 | -0.0586174 |
| TSTA3 | -0.0586213 |
| ZNF764 | -0.0586400 |
| MYOCD | -0.0586414 |
| SSTR1 | -0.0586418 |
| DEC1 | -0.0586842 |
| SLC2A2 | -0.0586845 |
| NUDCD1 | -0.0586958 |
| EFCAB3 | -0.0586961 |
| DCTN1 | -0.0586968 |
| SPIN1 | -0.0587219 |
| ECHS1 | -0.0587256 |
| CLDN18 | -0.0587651 |
| EMC4 | -0.0587662 |
| COX7B | -0.0587682 |
| OR10J1 | -0.0587820 |
| C12orf40 | -0.0587837 |
| LRRC3B | -0.0587973 |
| SNW1 | -0.0588148 |
| TMOD4 | -0.0588274 |
| PTRF | -0.0588284 |
| SLC26A11 | -0.0588294 |
| OFD1 | -0.0588614 |
| PNN | -0.0588649 |
| DNAJB4 | -0.0588832 |
| CNTLN | -0.0588868 |
| IAH1 | -0.0588972 |
| RFX4 | -0.0588987 |
| RASGRF2 | -0.0589158 |
| PF4V1 | -0.0589393 |
| EMR3 | -0.0589464 |
| BIRC6 | -0.0589530 |
| POLN | -0.0589712 |
| ADAM30 | -0.0589735 |
| HHLA2 | -0.0589868 |
| GRK7 | -0.0590032 |
| ATPAF1 | -0.0590219 |
| INTS3 | -0.0590236 |
| SLC25A14 | -0.0590318 |
| FAM71A | -0.0590388 |
| SCAI | -0.0590395 |
| AJUBA | -0.0590501 |
| TAS2R4 | -0.0590551 |
| C5orf47 | -0.0590574 |
| MAPK15 | -0.0590582 |
| SCP2D1 | -0.0590698 |
| TTLL11 | -0.0590889 |
| CNTN2 | -0.0591077 |
| EML6 | -0.0591166 |
| GSX2 | -0.0591658 |
| PGK2 | -0.0591723 |
| OR2W3 | -0.0591747 |
| MASP1 | -0.0591778 |
| KPNA1 | -0.0591880 |
| VPS52 | -0.0591941 |
| KBTBD2 | -0.0591964 |
| LCE1B | -0.0591980 |
| RPS15A | -0.0591997 |
| ZNF507 | -0.0592048 |
| ZNF804B | -0.0592075 |
| DLX1 | -0.0592224 |
| ELP6 | -0.0592309 |
| LDHAL6A | -0.0592406 |
| PIP5K1A | -0.0592441 |
| C5orf50 | -0.0592491 |
| C8orf4 | -0.0592955 |
| ZNF229 | -0.0593120 |
| CYP8B1 | -0.0593206 |
| KCNH5 | -0.0593398 |
| DMRTB1 | -0.0593595 |
| CRTC1 | -0.0593794 |
| DDX3Y | -0.0593896 |
| FAM19A4 | -0.0593962 |
| SCN9A | -0.0594236 |
| NUP35 | -0.0594292 |
| CPN1 | -0.0594317 |
| FLVCR1 | -0.0594547 |
| ROR2 | -0.0594595 |
| CAPN7 | -0.0594667 |
| TULP3 | -0.0594729 |
| NPPA | -0.0594737 |
| ARNTL | -0.0594742 |
| GID8 | -0.0594747 |
| SLC35F4 | -0.0594787 |
| RASSF6 | -0.0595259 |
| G6PC | -0.0595410 |
| SLC41A3 | -0.0595465 |
| CYP7A1 | -0.0595477 |
| PPP1R35 | -0.0595579 |
| U2AF2 | -0.0595702 |
| TBC1D21 | -0.0595766 |
| SUPT7L | -0.0595784 |
| ANXA7 | -0.0595820 |
| CXorf36 | -0.0595955 |
| FAM98B | -0.0596013 |
| PIBF1 | -0.0596106 |
| PLCH2 | -0.0596184 |
| IFNA8 | -0.0596216 |
| FGF17 | -0.0596255 |
| NKX6-2 | -0.0596784 |
| FMOD | -0.0596854 |
| NKD1 | -0.0597045 |
| ESRRG | -0.0597299 |
| EPX | -0.0597318 |
| OTUD5 | -0.0597450 |
| NUDT14 | -0.0597652 |
| GTPBP10 | -0.0597676 |
| SLC39A3 | -0.0597804 |
| VAPB | -0.0597874 |
| RELN | -0.0598076 |
| USP32 | -0.0598095 |
| PPP1R12B | -0.0598212 |
| USP34 | -0.0598260 |
| LPHN3 | -0.0598314 |
| GPR112 | -0.0598357 |
| CDK9 | -0.0598496 |
| UNC5D | -0.0598573 |
| MCF2L2 | -0.0598614 |
| PROX2 | -0.0598859 |
| ZNF630 | -0.0599161 |
| NDE1 | -0.0599294 |
| DEPDC4 | -0.0599328 |
| CLTB | -0.0599346 |
| ZNF536 | -0.0599390 |
| ZNF780A | -0.0599433 |
| ASPRV1 | -0.0599737 |
| BMP10 | -0.0599740 |
| NRSN1 | -0.0599797 |
| RTBDN | -0.0599961 |
| GTF3C3 | -0.0600436 |
| ADO | -0.0600449 |
| MTX2 | -0.0600673 |
| IFNL3 | -0.0600697 |
| PPEF2 | -0.0600698 |
| NAA38 | -0.0600735 |
| RPTN | -0.0600813 |
| OPRM1 | -0.0601068 |
| BRPF3 | -0.0601136 |
| RBBP6 | -0.0601259 |
| ARL8A | -0.0601270 |
| MTERF | -0.0601307 |
| SPDYA | -0.0601472 |
| LARP1B | -0.0601542 |
| TKTL2 | -0.0601587 |
| R3HCC1 | -0.0601878 |
| VN1R2 | -0.0602159 |
| MAD1L1 | -0.0602203 |
| WHSC1 | -0.0602248 |
| PEX5L | -0.0602335 |
| HPSE2 | -0.0602556 |
| RIMKLB | -0.0602816 |
| DAZ2 | -0.0602860 |
| ZRANB3 | -0.0603052 |
| PPP2R2D | -0.0603167 |
| CHMP5 | -0.0603315 |
| OXR1 | -0.0603474 |
| FGF5 | -0.0603511 |
| C12orf50 | -0.0603914 |
| CT45A1 | -0.0603921 |
| RANBP3 | -0.0603959 |
| MYOM3 | -0.0603986 |
| SMAD1 | -0.0604115 |
| ANKRD60 | -0.0604194 |
| C17orf75 | -0.0604673 |
| LMOD3 | -0.0604675 |
| YIPF5 | -0.0604718 |
| CPA1 | -0.0604786 |
| SLC29A1 | -0.0605184 |
| ZBTB11 | -0.0605341 |
| CYP24A1 | -0.0605479 |
| HPS6 | -0.0605583 |
| PRTN3 | -0.0605630 |
| CRISP1 | -0.0605649 |
| ATIC | -0.0605719 |
| ESCO1 | -0.0605745 |
| ZNF280A | -0.0605797 |
| MFSD4 | -0.0605874 |
| MDM4 | -0.0606324 |
| TSPYL2 | -0.0606396 |
| KCNMA1 | -0.0606488 |
| NDUFB4 | -0.0606797 |
| TRHDE | -0.0606994 |
| FBXL14 | -0.0607017 |
| ORMDL2 | -0.0607024 |
| NXPH2 | -0.0607194 |
| CACNA2D1 | -0.0607251 |
| TMEM225 | -0.0607482 |
| CCDC142 | -0.0608053 |
| DEFB127 | -0.0608065 |
| PKD2L1 | -0.0608180 |
| DSC1 | -0.0608270 |
| ZPBP2 | -0.0608373 |
| SCRT2 | -0.0608395 |
| MEDAG | -0.0608435 |
| GABRA4 | -0.0608544 |
| PMEPA1 | -0.0608604 |
| DCAF5 | -0.0608626 |
| ZNF471 | -0.0608630 |
| C4orf26 | -0.0608673 |
| ZNF326 | -0.0608871 |
| FLRT1 | -0.0609150 |
| OR1F1 | -0.0609278 |
| C5orf52 | -0.0609430 |
| PP2D1 | -0.0609639 |
| FGF19 | -0.0609673 |
| MFSD5 | -0.0609857 |
| KCNN2 | -0.0609883 |
| MROH9 | -0.0609927 |
| NOXRED1 | -0.0610096 |
| AK9 | -0.0610208 |
| C4orf6 | -0.0610242 |
| FAM47A | -0.0610469 |
| PPP2R3B | -0.0610494 |
| SH2D4B | -0.0610645 |
| ARFGEF2 | -0.0610667 |
| RNH1 | -0.0610804 |
| TAAR1 | -0.0610912 |
| AMELX | -0.0610928 |
| CD300LD | -0.0610936 |
| CRB2 | -0.0611004 |
| CDY2A | -0.0611006 |
| AHSP | -0.0611056 |
| SYNJ1 | -0.0611056 |
| SETD1A | -0.0611104 |
| CTBS | -0.0611150 |
| TANC1 | -0.0611216 |
| ERCC8 | -0.0611295 |
| EPHA5 | -0.0611474 |
| SNTG1 | -0.0611484 |
| STPG2 | -0.0611504 |
| METTL10 | -0.0611596 |
| RBM20 | -0.0611654 |
| DCUN1D4 | -0.0611667 |
| TLL1 | -0.0611910 |
| PCDH11X | -0.0612059 |
| TRIM41 | -0.0612090 |
| SERPINA12 | -0.0612132 |
| BOK | -0.0612221 |
| TMEM160 | -0.0612226 |
| GAREM | -0.0612263 |
| REV1 | -0.0612288 |
| FAM71C | -0.0612368 |
| LOXHD1 | -0.0612416 |
| RP2 | -0.0612451 |
| C6orf195 | -0.0612479 |
| ZNF747 | -0.0612500 |
| SIN3A | -0.0612510 |
| PLD5 | -0.0612712 |
| ZNF789 | -0.0612715 |
| KLHL40 | -0.0612874 |
| EVI5L | -0.0612892 |
| FSIP2 | -0.0612893 |
| SLC35F1 | -0.0612899 |
| GJB2 | -0.0612989 |
| MEGF11 | -0.0613075 |
| MTG1 | -0.0613182 |
| PECR | -0.0613407 |
| TBR1 | -0.0613854 |
| SBDS | -0.0613863 |
| DUSP19 | -0.0613879 |
| B4GALNT3 | -0.0613975 |
| CDH20 | -0.0614007 |
| IRF2BP2 | -0.0614078 |
| SLC26A6 | -0.0614153 |
| CABP2 | -0.0614182 |
| TNMD | -0.0614400 |
| TECTB | -0.0614557 |
| LENG1 | -0.0614670 |
| NPHP4 | -0.0614761 |
| AGXT2 | -0.0614842 |
| BICD1 | -0.0615135 |
| GNPNAT1 | -0.0615222 |
| OPTC | -0.0615349 |
| TAS2R42 | -0.0615479 |
| KHNYN | -0.0615579 |
| C16orf46 | -0.0615786 |
| C7orf62 | -0.0615788 |
| EDA | -0.0615844 |
| NKX6-1 | -0.0615916 |
| AGO4 | -0.0615929 |
| CRISP3 | -0.0616325 |
| RGS8 | -0.0616400 |
| TRPV3 | -0.0616431 |
| NOX3 | -0.0616455 |
| GAK | -0.0616478 |
| CHCHD6 | -0.0616563 |
| PHKG1 | -0.0616635 |
| OR51E1 | -0.0616721 |
| KRTAP4-3 | -0.0616775 |
| AFAP1 | -0.0616803 |
| VAT1L | -0.0616850 |
| PUS7L | -0.0617144 |
| CD59 | -0.0617262 |
| CBWD6 | -0.0617319 |
| C2orf57 | -0.0617427 |
| C2orf83 | -0.0617545 |
| GJA9 | -0.0617609 |
| KIAA0825 | -0.0617626 |
| EGR4 | -0.0617683 |
| C12orf61 | -0.0617695 |
| NLRP6 | -0.0617757 |
| MB | -0.0617833 |
| SLC4A9 | -0.0617976 |
| ZNF155 | -0.0618041 |
| SAFB2 | -0.0618173 |
| ZNF248 | -0.0618183 |
| PIH1D1 | -0.0618185 |
| TSTD2 | -0.0618431 |
| SLC20A1 | -0.0618476 |
| RNF133 | -0.0618656 |
| TPH2 | -0.0618744 |
| JAZF1 | -0.0618839 |
| MEIG1 | -0.0618885 |
| HERC3 | -0.0618962 |
| DNASE2B | -0.0618994 |
| FNDC7 | -0.0619271 |
| ZIC2 | -0.0619281 |
| TOLLIP | -0.0619356 |
| CACNB4 | -0.0619444 |
| AK1 | -0.0619524 |
| ZNF140 | -0.0619573 |
| NYAP2 | -0.0619663 |
| RB1CC1 | -0.0619739 |
| RBBP5 | -0.0619896 |
| IGDCC4 | -0.0619935 |
| CCDC146 | -0.0620187 |
| TEX15 | -0.0620246 |
| SLC9B2 | -0.0620266 |
| RIPK3 | -0.0620296 |
| PPA2 | -0.0620579 |
| KRT82 | -0.0620713 |
| MAGEC3 | -0.0620788 |
| AFF1 | -0.0620887 |
| ISPD | -0.0620959 |
| OLIG3 | -0.0621039 |
| TFAP2D | -0.0621252 |
| SS18 | -0.0621302 |
| TPR | -0.0621372 |
| DGKI | -0.0621710 |
| DHRS12 | -0.0621869 |
| RFX3 | -0.0621933 |
| AP5S1 | -0.0621985 |
| FBXO39 | -0.0622180 |
| INPP5A | -0.0622198 |
| PPP2CB | -0.0622312 |
| KRT40 | -0.0622352 |
| DLX4 | -0.0622394 |
| RBBP8NL | -0.0622509 |
| BTG4 | -0.0622709 |
| TMEM117 | -0.0622960 |
| SELV | -0.0623328 |
| C14orf177 | -0.0623390 |
| POLE4 | -0.0623563 |
| ZNF114 | -0.0623897 |
| AIPL1 | -0.0624016 |
| SPATA24 | -0.0624085 |
| TMCO6 | -0.0624132 |
| ERCC6L2 | -0.0624275 |
| FAM43A | -0.0624339 |
| KCNA1 | -0.0624395 |
| RPS6KA6 | -0.0624439 |
| FAM205A | -0.0624574 |
| SESN1 | -0.0624647 |
| PHPT1 | -0.0624674 |
| MAP3K15 | -0.0624709 |
| EML3 | -0.0624940 |
| AFTPH | -0.0625022 |
| FAM217A | -0.0625036 |
| TNFSF18 | -0.0625150 |
| GATA4 | -0.0625207 |
| KIF2B | -0.0625277 |
| TSPEAR | -0.0625292 |
| GCSH | -0.0625358 |
| SYS1 | -0.0625534 |
| SGSM1 | -0.0625669 |
| SPACA7 | -0.0625744 |
| IQCF3 | -0.0625767 |
| CACNA2D3 | -0.0625808 |
| ZFPM1 | -0.0625852 |
| ATCAY | -0.0626120 |
| NBEAL1 | -0.0626143 |
| FAM178A | -0.0626164 |
| AQPEP | -0.0626168 |
| PTHLH | -0.0626221 |
| SSX7 | -0.0626243 |
| EIF4G3 | -0.0626424 |
| MSTN | -0.0626639 |
| PIKFYVE | -0.0626684 |
| ZIC3 | -0.0626700 |
| GRIK2 | -0.0627303 |
| ZKSCAN3 | -0.0627322 |
| DAW1 | -0.0627364 |
| MTFR1L | -0.0627420 |
| DHH | -0.0627546 |
| LRRC71 | -0.0627582 |
| TRPC7 | -0.0627861 |
| SYCP1 | -0.0627865 |
| RNF170 | -0.0628012 |
| ZNF555 | -0.0628146 |
| HGFAC | -0.0628501 |
| IL1A | -0.0628617 |
| GPR89B | -0.0628732 |
| LENG9 | -0.0628739 |
| SLC17A8 | -0.0628828 |
| OSGIN2 | -0.0628960 |
| OR6A2 | -0.0629233 |
| UNC79 | -0.0629235 |
| ZC3H13 | -0.0629304 |
| C3orf62 | -0.0629311 |
| LRRC7 | -0.0629414 |
| SEPN1 | -0.0629751 |
| DDX53 | -0.0629900 |
| KY | -0.0629935 |
| GSAP | -0.0630017 |
| ANKRD62 | -0.0630375 |
| ART4 | -0.0630429 |
| IL37 | -0.0630523 |
| ZNF41 | -0.0630724 |
| OR1G1 | -0.0630905 |
| PKN2 | -0.0630938 |
| MIB2 | -0.0631081 |
| C6orf118 | -0.0631357 |
| CTRB1 | -0.0631428 |
| MCHR2 | -0.0631452 |
| ASB17 | -0.0631548 |
| KCNK4 | -0.0631588 |
| POLR3A | -0.0631714 |
| ZNF578 | -0.0631738 |
| CLOCK | -0.0631754 |
| MRPS26 | -0.0632282 |
| AGFG2 | -0.0632284 |
| ERCC4 | -0.0632363 |
| DENND4A | -0.0632532 |
| NEDD8 | -0.0632658 |
| TAT | -0.0632730 |
| NPHS1 | -0.0632749 |
| VPS51 | -0.0632842 |
| ADCY8 | -0.0632916 |
| C8orf44 | -0.0633038 |
| SLITRK2 | -0.0633109 |
| PARP6 | -0.0633130 |
| HAS2 | -0.0633215 |
| XKR3 | -0.0633320 |
| PROL1 | -0.0633372 |
| C6orf25 | -0.0634023 |
| CRYGC | -0.0634343 |
| EFR3A | -0.0634363 |
| RPLP1 | -0.0634368 |
| POLE | -0.0634551 |
| METTL22 | -0.0634593 |
| AKAP5 | -0.0634845 |
| PCDHGB1 | -0.0635181 |
| AP2A1 | -0.0635193 |
| BMP3 | -0.0635288 |
| ANKK1 | -0.0635366 |
| HPCAL4 | -0.0635430 |
| KIAA1586 | -0.0635652 |
| FCER2 | -0.0635688 |
| CHRNA4 | -0.0636293 |
| GABRR2 | -0.0636405 |
| CIDEC | -0.0636660 |
| CHMP1B | -0.0637235 |
| CTPS2 | -0.0637388 |
| RSPO2 | -0.0637503 |
| PRTG | -0.0637636 |
| CACNG2 | -0.0637735 |
| CTCFL | -0.0637744 |
| GAL3ST3 | -0.0637839 |
| PLEKHG3 | -0.0637893 |
| GAS7 | -0.0637906 |
| PDLIM2 | -0.0637934 |
| RSAD1 | -0.0637939 |
| ZCRB1 | -0.0637949 |
| MAGEB3 | -0.0638087 |
| CYP2C8 | -0.0638328 |
| STK11 | -0.0638336 |
| GPR85 | -0.0638440 |
| MFSD8 | -0.0638518 |
| NRG3 | -0.0638578 |
| CD5L | -0.0638610 |
| ACVR1C | -0.0638645 |
| LRIT2 | -0.0638691 |
| GPR133 | -0.0638981 |
| UBE2H | -0.0639617 |
| FAM166B | -0.0639825 |
| EHBP1 | -0.0639894 |
| OR11G2 | -0.0640261 |
| C5orf42 | -0.0640277 |
| MOV10L1 | -0.0640287 |
| TECTA | -0.0640554 |
| APOF | -0.0640626 |
| FABP2 | -0.0640814 |
| CNTNAP4 | -0.0640851 |
| ABHD13 | -0.0640858 |
| TRPC5 | -0.0641097 |
| HUNK | -0.0641116 |
| EVC | -0.0641152 |
| AGTR2 | -0.0641198 |
| GATAD2B | -0.0641534 |
| RNF112 | -0.0641547 |
| TRMT1 | -0.0641981 |
| SPP2 | -0.0642000 |
| TBX5 | -0.0642201 |
| HRH4 | -0.0642276 |
| GOT2 | -0.0642298 |
| CD302 | -0.0642407 |
| SENP1 | -0.0642541 |
| RTN4RL2 | -0.0642560 |
| SERINC5 | -0.0642666 |
| RERE | -0.0642680 |
| MTNR1A | -0.0642762 |
| KCNIP4 | -0.0642862 |
| RTP1 | -0.0642974 |
| ZNF681 | -0.0642978 |
| RNF7 | -0.0643010 |
| SYCE2 | -0.0643282 |
| STAG2 | -0.0643325 |
| HNF4G | -0.0643352 |
| GRPEL2 | -0.0643746 |
| ULK3 | -0.0643758 |
| NLRP11 | -0.0643795 |
| MYL3 | -0.0643814 |
| DCAF10 | -0.0643991 |
| ZPLD1 | -0.0644021 |
| XRCC6BP1 | -0.0644061 |
| GRAPL | -0.0644073 |
| IZUMO1 | -0.0644133 |
| ADH6 | -0.0644203 |
| UNC50 | -0.0644223 |
| POLL | -0.0644291 |
| CCER1 | -0.0644544 |
| DDX56 | -0.0644629 |
| GRIA3 | -0.0644656 |
| CENPB | -0.0644658 |
| CALB1 | -0.0644716 |
| ANKRD34A | -0.0644841 |
| SMIM20 | -0.0644846 |
| ROBO4 | -0.0644849 |
| FKBP9 | -0.0644906 |
| UGT2A3 | -0.0645059 |
| MECR | -0.0645498 |
| BAAT | -0.0645586 |
| ZNF354C | -0.0645635 |
| OPN5 | -0.0645827 |
| MYPN | -0.0645857 |
| IL5 | -0.0645943 |
| DIEXF | -0.0646244 |
| DPYS | -0.0646306 |
| ZNF669 | -0.0646353 |
| ELOVL7 | -0.0646382 |
| IL19 | -0.0646681 |
| SLC6A1 | -0.0646691 |
| NUAK2 | -0.0647079 |
| LHFPL3 | -0.0647293 |
| BCS1L | -0.0647385 |
| CEP112 | -0.0647535 |
| KRTAP4-4 | -0.0647678 |
| GPN3 | -0.0647709 |
| TRIM13 | -0.0647850 |
| SLC9C2 | -0.0647876 |
| ZNF765 | -0.0647933 |
| GIF | -0.0647999 |
| PRDM12 | -0.0648121 |
| GAD2 | -0.0648536 |
| C19orf68 | -0.0648560 |
| ZNF300 | -0.0648569 |
| UBE2W | -0.0648864 |
| SREBF1 | -0.0649064 |
| FAM26E | -0.0649099 |
| HSD3B7 | -0.0649162 |
| ARL10 | -0.0649164 |
| ELP5 | -0.0649221 |
| MYLIP | -0.0649316 |
| IQSEC2 | -0.0649408 |
| BLID | -0.0649480 |
| NTSR2 | -0.0649502 |
| KRAS | -0.0649554 |
| SMAD5 | -0.0650277 |
| USP37 | -0.0650280 |
| C2orf69 | -0.0650282 |
| APOH | -0.0650312 |
| IRS4 | -0.0650395 |
| SRP9 | -0.0650440 |
| KIF27 | -0.0650621 |
| C11orf65 | -0.0651250 |
| NAV2 | -0.0651360 |
| LIPI | -0.0651643 |
| MRGPRD | -0.0651729 |
| FAM46D | -0.0651798 |
| CACHD1 | -0.0651893 |
| MIER3 | -0.0651907 |
| CDH15 | -0.0651917 |
| CFHR5 | -0.0651924 |
| RANBP17 | -0.0651989 |
| RHBDD1 | -0.0652054 |
| MAS1 | -0.0652155 |
| C9orf9 | -0.0652256 |
| NRL | -0.0652483 |
| ADCY4 | -0.0652544 |
| FAM210A | -0.0652674 |
| RAD9A | -0.0652746 |
| FITM1 | -0.0652753 |
| AAR2 | -0.0652808 |
| IL31 | -0.0652868 |
| PINK1 | -0.0652957 |
| ZNF81 | -0.0653301 |
| SH3BGRL2 | -0.0653332 |
| PCDH15 | -0.0653414 |
| RRP12 | -0.0653558 |
| PGM2 | -0.0653607 |
| CCDC73 | -0.0653704 |
| SMLR1 | -0.0653814 |
| GYPE | -0.0653822 |
| ATPAF2 | -0.0653846 |
| SPZ1 | -0.0653875 |
| NFKBIZ | -0.0653896 |
| IFNW1 | -0.0653940 |
| PAPPA2 | -0.0653943 |
| HIST3H2BB | -0.0654549 |
| CYP2C19 | -0.0654647 |
| NCOA1 | -0.0654782 |
| RAD51C | -0.0654908 |
| PKHD1 | -0.0654909 |
| HDAC6 | -0.0654912 |
| PAQR9 | -0.0654942 |
| FRMPD2 | -0.0654950 |
| ITIH5 | -0.0654955 |
| DLK2 | -0.0654998 |
| NKTR | -0.0655300 |
| DHRS7B | -0.0655494 |
| HSFY2 | -0.0655838 |
| NAB2 | -0.0655936 |
| MS4A6E | -0.0656059 |
| GDA | -0.0656090 |
| POLD2 | -0.0656175 |
| RBM12B | -0.0656220 |
| ZMAT3 | -0.0656221 |
| NT5C1B | -0.0656590 |
| CRYBA1 | -0.0656758 |
| NUCKS1 | -0.0656784 |
| ANKH | -0.0657019 |
| KCND1 | -0.0657030 |
| CIR1 | -0.0657046 |
| FAM177A1 | -0.0657051 |
| NARS2 | -0.0657077 |
| DPM2 | -0.0657457 |
| NUDT2 | -0.0657627 |
| HIPK1 | -0.0657713 |
| NDUFB1 | -0.0657716 |
| PRELP | -0.0657852 |
| BAALC | -0.0657907 |
| TDRD6 | -0.0657960 |
| DUOXA1 | -0.0658005 |
| ERF | -0.0658155 |
| USP19 | -0.0658177 |
| NYAP1 | -0.0658265 |
| PIWIL1 | -0.0658704 |
| BTBD19 | -0.0658980 |
| ERVW-1 | -0.0659091 |
| MMP27 | -0.0659112 |
| CCDC132 | -0.0659207 |
| RANGRF | -0.0659269 |
| INPPL1 | -0.0659606 |
| C15orf56 | -0.0659862 |
| ADH7 | -0.0660041 |
| PTPRU | -0.0660043 |
| WIBG | -0.0660302 |
| RXFP1 | -0.0660675 |
| FZD10 | -0.0660769 |
| SLC9A3 | -0.0660940 |
| PGBD1 | -0.0661184 |
| RAB11FIP2 | -0.0661241 |
| ABCG8 | -0.0661310 |
| OTUB2 | -0.0661491 |
| TCP10 | -0.0661786 |
| LRIT1 | -0.0662037 |
| TAF3 | -0.0662047 |
| SERPINB10 | -0.0662106 |
| GABRA2 | -0.0662112 |
| CYLC2 | -0.0662214 |
| RPS5 | -0.0662391 |
| AACS | -0.0662406 |
| PRMT3 | -0.0662409 |
| DEFB119 | -0.0662468 |
| C17orf64 | -0.0662586 |
| CEACAM8 | -0.0662594 |
| PXMP2 | -0.0662654 |
| MAMDC2 | -0.0662677 |
| COBLL1 | -0.0662689 |
| C4BPB | -0.0662797 |
| TSPAN19 | -0.0662822 |
| MRPL23 | -0.0663031 |
| CXorf22 | -0.0663039 |
| IRF2BP1 | -0.0663071 |
| PMPCB | -0.0663088 |
| WDR49 | -0.0663232 |
| TMEM44 | -0.0663356 |
| SOX14 | -0.0663357 |
| ZFYVE9 | -0.0663389 |
| GOLGA6L6 | -0.0663492 |
| HSBP1L1 | -0.0663559 |
| DEFB105B | -0.0663824 |
| HORMAD2 | -0.0663870 |
| PRAMEF3 | -0.0663937 |
| C14orf93 | -0.0664057 |
| CCDC15 | -0.0664077 |
| LNPEP | -0.0664464 |
| MUC22 | -0.0664534 |
| OLA1 | -0.0664676 |
| WFDC11 | -0.0664820 |
| LRRC20 | -0.0665209 |
| GRIA4 | -0.0665593 |
| SLC9B1 | -0.0665610 |
| TMEM168 | -0.0665827 |
| GNMT | -0.0665867 |
| TMEM14E | -0.0665910 |
| HSPA4 | -0.0665915 |
| P2RX6 | -0.0666264 |
| TAS2R41 | -0.0666311 |
| PIP4K2C | -0.0666495 |
| LRPAP1 | -0.0666706 |
| TMEM254 | -0.0666784 |
| C5orf64 | -0.0666879 |
| RIT1 | -0.0666905 |
| UROC1 | -0.0667012 |
| RPS9 | -0.0667077 |
| ZNF792 | -0.0667490 |
| ANO7 | -0.0668086 |
| PEBP1 | -0.0668236 |
| CCDC13 | -0.0668345 |
| MAT1A | -0.0668393 |
| MAVS | -0.0668416 |
| DEFA1 | -0.0668419 |
| CXorf58 | -0.0668455 |
| TTC5 | -0.0668570 |
| KIT | -0.0668783 |
| ANAPC2 | -0.0668821 |
| TRAPPC3L | -0.0669073 |
| TMEM33 | -0.0669341 |
| VPS13C | -0.0669461 |
| CCR9 | -0.0669490 |
| ZKSCAN8 | -0.0669689 |
| PODXL | -0.0669858 |
| PPAPDC2 | -0.0669923 |
| HNRNPA1 | -0.0669958 |
| HSPA1L | -0.0670150 |
| CTC1 | -0.0670281 |
| TTLL2 | -0.0670289 |
| POU6F1 | -0.0670310 |
| LIN7B | -0.0670335 |
| COMMD5 | -0.0670914 |
| ABHD8 | -0.0670938 |
| ILDR1 | -0.0671033 |
| PRSS37 | -0.0671105 |
| C12orf74 | -0.0671209 |
| PRKRA | -0.0671418 |
| YLPM1 | -0.0671689 |
| BPIFB6 | -0.0671756 |
| NFE2L1 | -0.0671885 |
| ADCK1 | -0.0671989 |
| ARIH2OS | -0.0672126 |
| CAMK2N2 | -0.0672141 |
| UTY | -0.0672268 |
| STX1B | -0.0672404 |
| DHX40 | -0.0672479 |
| C8orf17 | -0.0672515 |
| AIFM2 | -0.0672517 |
| CDH26 | -0.0672755 |
| KNDC1 | -0.0672974 |
| RAG2 | -0.0673139 |
| TROVE2 | -0.0673167 |
| PPWD1 | -0.0673352 |
| ANK1 | -0.0673452 |
| A1CF | -0.0673569 |
| SLC5A4 | -0.0673660 |
| NAPA | -0.0673667 |
| EDDM3A | -0.0673681 |
| TMEM202 | -0.0673714 |
| EP400NL | -0.0673793 |
| C8orf31 | -0.0673934 |
| PDE3A | -0.0674000 |
| IGBP1 | -0.0674006 |
| TRAP1 | -0.0674119 |
| CTIF | -0.0674178 |
| RBM45 | -0.0674226 |
| LDHAL6B | -0.0674233 |
| SEC24B | -0.0674235 |
| PDE4A | -0.0674306 |
| TRIM61 | -0.0674362 |
| BTBD10 | -0.0674755 |
| CYFIP2 | -0.0674782 |
| WBP2NL | -0.0674924 |
| KCNJ13 | -0.0674966 |
| C14orf23 | -0.0674990 |
| SETD7 | -0.0675012 |
| ELL3 | -0.0675038 |
| PNPLA2 | -0.0675515 |
| ZMYND11 | -0.0675582 |
| FBXO8 | -0.0675623 |
| NLGN4Y | -0.0675691 |
| IPO4 | -0.0675694 |
| TEX26 | -0.0675744 |
| GAPVD1 | -0.0675935 |
| SLC23A1 | -0.0675985 |
| NUDCD2 | -0.0676121 |
| AGMO | -0.0676276 |
| CCT6B | -0.0676464 |
| EPPIN | -0.0676525 |
| ASIC5 | -0.0676527 |
| PLA2G2E | -0.0676560 |
| ISX | -0.0676612 |
| LRRC43 | -0.0676684 |
| HNF4A | -0.0676736 |
| PMEL | -0.0676870 |
| HOXA2 | -0.0676870 |
| GNRHR | -0.0676882 |
| ZNF773 | -0.0676887 |
| ATP6V0A1 | -0.0676911 |
| C5orf28 | -0.0677015 |
| PNLIPRP1 | -0.0677064 |
| SLC46A2 | -0.0677076 |
| ASAP2 | -0.0677159 |
| TSGA13 | -0.0677171 |
| LIN28A | -0.0677327 |
| ANKRD2 | -0.0677425 |
| CCDC140 | -0.0677445 |
| GGNBP1 | -0.0677568 |
| CD300LG | -0.0677649 |
| SLC22A24 | -0.0677651 |
| VTN | -0.0677682 |
| HIST4H4 | -0.0677734 |
| NDFIP2 | -0.0677802 |
| ITIH2 | -0.0677825 |
| ARL14 | -0.0678173 |
| UCP1 | -0.0678240 |
| ANKRD24 | -0.0678336 |
| ZNF608 | -0.0678371 |
| PLK2 | -0.0678544 |
| APLNR | -0.0678559 |
| AGRN | -0.0678569 |
| SLC35G2 | -0.0678651 |
| ERG | -0.0678691 |
| RRNAD1 | -0.0678758 |
| FEZF2 | -0.0679013 |
| AXIN1 | -0.0679040 |
| ZBTB6 | -0.0679132 |
| XKR4 | -0.0679146 |
| NANP | -0.0679332 |
| SMIM9 | -0.0679393 |
| CDK5 | -0.0679449 |
| NMBR | -0.0679478 |
| OFCC1 | -0.0679975 |
| TCF21 | -0.0680201 |
| TMEM209 | -0.0680224 |
| FAM35A | -0.0680259 |
| FAM106A | -0.0680282 |
| ZNF84 | -0.0680695 |
| C9orf135 | -0.0680759 |
| SSUH2 | -0.0681045 |
| GJA8 | -0.0681049 |
| PRDM9 | -0.0681238 |
| GALE | -0.0681372 |
| COX18 | -0.0681378 |
| GLT8D2 | -0.0681699 |
| DPY19L3 | -0.0681716 |
| WHAMM | -0.0681734 |
| M1AP | -0.0682218 |
| GCG | -0.0682230 |
| ZNF181 | -0.0682256 |
| BIRC8 | -0.0682631 |
| TM9SF4 | -0.0682672 |
| PAGE4 | -0.0682809 |
| ZCCHC7 | -0.0682836 |
| THSD7B | -0.0682861 |
| KIAA0368 | -0.0682874 |
| GABRA6 | -0.0682922 |
| NPFFR2 | -0.0682972 |
| TCEAL8 | -0.0683249 |
| ENAM | -0.0683789 |
| CER1 | -0.0684015 |
| TRIM51 | -0.0684059 |
| F9 | -0.0684087 |
| ALDH5A1 | -0.0684188 |
| SLMO2 | -0.0684233 |
| LONP2 | -0.0684360 |
| ALKBH1 | -0.0684543 |
| TMEM259 | -0.0684606 |
| C4orf47 | -0.0684718 |
| ZNF684 | -0.0685012 |
| BCAP29 | -0.0685074 |
| LYZL2 | -0.0685133 |
| CD2BP2 | -0.0685137 |
| SI | -0.0685517 |
| DDI1 | -0.0685550 |
| TANGO6 | -0.0685583 |
| NCAN | -0.0685763 |
| SLC17A9 | -0.0685766 |
| ZNF639 | -0.0685948 |
| ZBTB43 | -0.0686061 |
| TASP1 | -0.0686154 |
| C5orf58 | -0.0686234 |
| SERPINB6 | -0.0686331 |
| GPD1 | -0.0686383 |
| CACNA1G | -0.0686422 |
| SFTA2 | -0.0686435 |
| APOBEC2 | -0.0686437 |
| CPSF3L | -0.0686497 |
| CYTH2 | -0.0686595 |
| GLI2 | -0.0686596 |
| PCYT1B | -0.0686880 |
| KCNQ4 | -0.0687002 |
| MARS2 | -0.0687067 |
| ITGB3BP | -0.0687210 |
| TMEM132B | -0.0687329 |
| CDH17 | -0.0687409 |
| VCX2 | -0.0687515 |
| AKT2 | -0.0687585 |
| DEFB125 | -0.0687833 |
| ELMOD2 | -0.0688023 |
| SLC22A18AS | -0.0688110 |
| CCDC28B | -0.0688151 |
| HIST1H1T | -0.0688268 |
| CCDC79 | -0.0688316 |
| PON3 | -0.0688328 |
| FAM110D | -0.0688953 |
| TDRD5 | -0.0689381 |
| FAM228A | -0.0689621 |
| ZNF658 | -0.0689983 |
| NIPBL | -0.0690021 |
| KIAA1024L | -0.0690107 |
| RRN3 | -0.0690274 |
| INTS12 | -0.0690572 |
| PEG3 | -0.0690582 |
| BAHD1 | -0.0690582 |
| CHST10 | -0.0690592 |
| CAST | -0.0690662 |
| GFAP | -0.0690830 |
| ANGPTL3 | -0.0690888 |
| SP7 | -0.0690954 |
| C1orf100 | -0.0691034 |
| RBP3 | -0.0691342 |
| AGBL5 | -0.0691638 |
| CHD5 | -0.0691648 |
| ZNF154 | -0.0691942 |
| C3orf30 | -0.0692020 |
| TSPYL4 | -0.0692180 |
| MACROD1 | -0.0692310 |
| LPPR5 | -0.0693011 |
| AGPAT6 | -0.0693020 |
| FANCM | -0.0693157 |
| TSSK2 | -0.0693194 |
| GFRAL | -0.0693480 |
| STARD9 | -0.0693540 |
| FNDC8 | -0.0693744 |
| TNFRSF10C | -0.0693792 |
| TMEM132D | -0.0693925 |
| MMAA | -0.0694247 |
| RGPD6 | -0.0694365 |
| DNAJB12 | -0.0694467 |
| PLEKHH2 | -0.0694712 |
| SLC28A2 | -0.0694747 |
| TUBGCP4 | -0.0694868 |
| RAPGEF6 | -0.0695261 |
| ZNF514 | -0.0695478 |
| MANEAL | -0.0696189 |
| APOA1BP | -0.0696191 |
| SLC25A25 | -0.0696398 |
| INTS6 | -0.0696593 |
| IKBKAP | -0.0696680 |
| USP26 | -0.0696716 |
| ABCG4 | -0.0696800 |
| PHF8 | -0.0696804 |
| C2orf68 | -0.0696839 |
| USH2A | -0.0697127 |
| DHRS7 | -0.0697127 |
| TBC1D16 | -0.0697194 |
| ZNF318 | -0.0697199 |
| SMIM10 | -0.0697205 |
| C1QTNF4 | -0.0697331 |
| SPRN | -0.0697382 |
| ADAMTSL2 | -0.0697521 |
| TTC40 | -0.0697583 |
| CNNM2 | -0.0697773 |
| PCDHB4 | -0.0698158 |
| ZFAND4 | -0.0698212 |
| CEP135 | -0.0698373 |
| PTPN9 | -0.0698459 |
| COL25A1 | -0.0698476 |
| HOXD1 | -0.0698617 |
| TARBP1 | -0.0698644 |
| SFTA3 | -0.0698664 |
| TNXB | -0.0698719 |
| SOX7 | -0.0698745 |
| ODF1 | -0.0698865 |
| PDZD9 | -0.0699226 |
| CSTL1 | -0.0699482 |
| TBL3 | -0.0699561 |
| SAMD13 | -0.0699632 |
| ZNF571 | -0.0699662 |
| ELMOD1 | -0.0699688 |
| PROCA1 | -0.0699716 |
| MYH1 | -0.0699836 |
| MRPS16 | -0.0700139 |
| JPH1 | -0.0700434 |
| KIF26A | -0.0700501 |
| TSPYL6 | -0.0700772 |
| NACA2 | -0.0700952 |
| PRSS22 | -0.0701021 |
| COPS8 | -0.0701149 |
| BEGAIN | -0.0701248 |
| ZNF660 | -0.0701659 |
| C19orf57 | -0.0701836 |
| ABCD3 | -0.0702085 |
| SNRK | -0.0702088 |
| MEIS1 | -0.0702377 |
| FAM47B | -0.0702552 |
| PCDH9 | -0.0702574 |
| C9orf47 | -0.0702942 |
| ZBTB49 | -0.0703034 |
| RPS13 | -0.0703047 |
| TSHZ2 | -0.0703127 |
| GGA1 | -0.0703307 |
| METTL14 | -0.0703439 |
| STRIP2 | -0.0703491 |
| SRY | -0.0703763 |
| ARRDC4 | -0.0703834 |
| DSPP | -0.0703853 |
| SLC5A8 | -0.0703941 |
| HPR | -0.0703999 |
| FOXP2 | -0.0704241 |
| PRDM6 | -0.0704262 |
| ZNF407 | -0.0704270 |
| SYT16 | -0.0704391 |
| RAB14 | -0.0704509 |
| POU2F1 | -0.0704575 |
| CABYR | -0.0704698 |
| ISM1 | -0.0704905 |
| ZNF772 | -0.0704939 |
| NEUROD6 | -0.0705305 |
| NAF1 | -0.0705367 |
| F13B | -0.0705431 |
| MIA2 | -0.0705479 |
| SLC13A5 | -0.0705632 |
| SYAP1 | -0.0705709 |
| DMD | -0.0705741 |
| PCDHB14 | -0.0705999 |
| TTPAL | -0.0706015 |
| ZBTB10 | -0.0706051 |
| DMBX1 | -0.0706078 |
| ITGB1BP2 | -0.0706292 |
| SCGB1C1 | -0.0706316 |
| KIAA0408 | -0.0706356 |
| PARN | -0.0706393 |
| ZNF586 | -0.0706717 |
| HSDL2 | -0.0706832 |
| NAPG | -0.0706978 |
| HSDL1 | -0.0707109 |
| PSG1 | -0.0707173 |
| SLC26A8 | -0.0707333 |
| IFNK | -0.0707488 |
| CSNK1A1L | -0.0707553 |
| NR0B2 | -0.0707627 |
| ABHD6 | -0.0707689 |
| MROH2A | -0.0707903 |
| KCNJ14 | -0.0708160 |
| IGF1 | -0.0708330 |
| FMN2 | -0.0708386 |
| CLEC1B | -0.0708489 |
| TRAM1 | -0.0708606 |
| RGS4 | -0.0708690 |
| HECW1 | -0.0708762 |
| GNAL | -0.0709017 |
| RAPGEFL1 | -0.0709025 |
| MAML3 | -0.0709159 |
| KRT36 | -0.0709184 |
| ARF4 | -0.0709194 |
| LHCGR | -0.0709276 |
| C1orf110 | -0.0709476 |
| QARS | -0.0709548 |
| ASB14 | -0.0709610 |
| LCE3A | -0.0709661 |
| NHLH2 | -0.0709707 |
| SCD5 | -0.0709810 |
| ZNF638 | -0.0709872 |
| MMP21 | -0.0710123 |
| C1orf180 | -0.0710141 |
| LYSMD3 | -0.0710145 |
| SECISBP2L | -0.0710258 |
| SHPRH | -0.0710456 |
| CALHM3 | -0.0710935 |
| TOR1AIP2 | -0.0710963 |
| ZFP3 | -0.0711020 |
| MT4 | -0.0711206 |
| GHITM | -0.0711217 |
| PGP | -0.0711300 |
| ZNF582 | -0.0711955 |
| AP3S2 | -0.0712097 |
| ANGPTL2 | -0.0712164 |
| ADPRHL1 | -0.0712337 |
| ZDHHC24 | -0.0712583 |
| MARCH9 | -0.0712638 |
| AQP12A | -0.0712671 |
| GPR1 | -0.0712677 |
| FBXO40 | -0.0712737 |
| PRMT8 | -0.0713268 |
| GUCA2A | -0.0713268 |
| APOM | -0.0713304 |
| ZNF645 | -0.0713394 |
| TBX1 | -0.0713617 |
| LRRC9 | -0.0713922 |
| OSER1 | -0.0713926 |
| POTEM | -0.0714290 |
| INPP5E | -0.0714338 |
| ZNF548 | -0.0714481 |
| RPUSD1 | -0.0714490 |
| PET100 | -0.0714525 |
| YAE1D1 | -0.0714548 |
| CD101 | -0.0714636 |
| SLCO1A2 | -0.0715082 |
| CCNA1 | -0.0715237 |
| CCDC144NL | -0.0715321 |
| FAM161A | -0.0715327 |
| RSG1 | -0.0715381 |
| RYBP | -0.0715426 |
| VAPA | -0.0715589 |
| MBTPS2 | -0.0715625 |
| CAT | -0.0715652 |
| ZNF254 | -0.0715719 |
| ST3GAL3 | -0.0715744 |
| ZNF430 | -0.0715980 |
| MMP11 | -0.0716062 |
| DEFB118 | -0.0716336 |
| SP4 | -0.0716639 |
| WWOX | -0.0716643 |
| PGF | -0.0716995 |
| TMEM257 | -0.0717060 |
| CDC73 | -0.0717348 |
| CBWD5 | -0.0717405 |
| MAP2K5 | -0.0717555 |
| GLIPR1L1 | -0.0717621 |
| NCOA6 | -0.0717790 |
| OR2T5 | -0.0717843 |
| UBR5 | -0.0717986 |
| UNC13A | -0.0718013 |
| TCTEX1D2 | -0.0718027 |
| MICU2 | -0.0718291 |
| CRTAC1 | -0.0718412 |
| ESRRB | -0.0718806 |
| CSTF2T | -0.0718826 |
| DAOA | -0.0719025 |
| GLIS1 | -0.0719286 |
| DNAJC28 | -0.0719384 |
| RBFOX3 | -0.0719424 |
| HEMGN | -0.0719426 |
| INSL4 | -0.0719441 |
| SLC52A1 | -0.0719580 |
| CLIP1 | -0.0719712 |
| CXorf40B | -0.0719885 |
| PRSS57 | -0.0720153 |
| PSG9 | -0.0720290 |
| RBPMS2 | -0.0720424 |
| C7 | -0.0720514 |
| PRKACG | -0.0720855 |
| PRSS54 | -0.0721188 |
| PTPN23 | -0.0721833 |
| NUP210L | -0.0722184 |
| STRADB | -0.0722283 |
| CCDC61 | -0.0722323 |
| HIST2H4B | -0.0722382 |
| GCM2 | -0.0722557 |
| TCF15 | -0.0722577 |
| ECD | -0.0722765 |
| ZFP28 | -0.0722913 |
| HTR1D | -0.0722946 |
| FBF1 | -0.0723351 |
| UQCC1 | -0.0723458 |
| WBP2 | -0.0723460 |
| TWSG1 | -0.0723463 |
| DCTN6 | -0.0723474 |
| FBP2 | -0.0723531 |
| ZNF45 | -0.0723827 |
| KCNG3 | -0.0724082 |
| FKBP3 | -0.0724118 |
| KCTD2 | -0.0724288 |
| FSCB | -0.0724468 |
| ZNF235 | -0.0724474 |
| CGREF1 | -0.0724647 |
| MAP3K19 | -0.0724897 |
| ARID4A | -0.0725022 |
| DHCR24 | -0.0725168 |
| GSG1L | -0.0725289 |
| CLDN17 | -0.0725634 |
| TMX3 | -0.0725671 |
| APOLD1 | -0.0725678 |
| SLC2A4RG | -0.0725703 |
| TCERG1L | -0.0725817 |
| MUC13 | -0.0726051 |
| SMIM7 | -0.0726178 |
| ANKRD1 | -0.0726238 |
| MUC5AC | -0.0726643 |
| SHOC2 | -0.0726996 |
| AWAT1 | -0.0727089 |
| SLC25A30 | -0.0727335 |
| METTL21C | -0.0727602 |
| BEND2 | -0.0727613 |
| ZCCHC8 | -0.0727949 |
| CCNI | -0.0728408 |
| ZNF468 | -0.0728425 |
| POMGNT2 | -0.0728481 |
| GJD4 | -0.0728682 |
| ATG16L1 | -0.0728699 |
| FRAS1 | -0.0728963 |
| PEAK1 | -0.0729067 |
| SRA1 | -0.0729317 |
| CD46 | -0.0729496 |
| SERINC4 | -0.0729687 |
| HIPK4 | -0.0729796 |
| COA5 | -0.0729803 |
| PCDHGC3 | -0.0729827 |
| RPS15 | -0.0729914 |
| EMC3 | -0.0730063 |
| NAT8 | -0.0730222 |
| BMX | -0.0730276 |
| FURIN | -0.0730319 |
| ADAMTS17 | -0.0730755 |
| FOXR1 | -0.0730757 |
| LCE2C | -0.0730877 |
| EYA4 | -0.0731152 |
| FAM115A | -0.0731353 |
| EPB41L4A | -0.0731368 |
| HBG1 | -0.0731448 |
| PIK3C3 | -0.0731507 |
| ZBTB12 | -0.0731766 |
| PBLD | -0.0731798 |
| FASTK | -0.0732100 |
| MRPL22 | -0.0732122 |
| MARK4 | -0.0732142 |
| BCAR1 | -0.0732587 |
| AOC2 | -0.0732679 |
| FKBP6 | -0.0732745 |
| LHX5 | -0.0732885 |
| AMER2 | -0.0732944 |
| AKR1C4 | -0.0732964 |
| VIP | -0.0733005 |
| CRYBA2 | -0.0733356 |
| ASXL3 | -0.0733411 |
| C1orf86 | -0.0733489 |
| SLC22A25 | -0.0733694 |
| CNGA4 | -0.0733974 |
| MCC | -0.0734028 |
| ATP7A | -0.0734159 |
| ZIM3 | -0.0734254 |
| ANP32D | -0.0734362 |
| GSPT1 | -0.0734649 |
| ZNF132 | -0.0735015 |
| L2HGDH | -0.0735043 |
| SERPINB12 | -0.0735181 |
| SERINC2 | -0.0735212 |
| MIEF2 | -0.0735304 |
| GCSAML | -0.0735507 |
| SNRPE | -0.0735766 |
| PPP1R9A | -0.0736065 |
| PSG3 | -0.0736082 |
| KLHL10 | -0.0736796 |
| CYB5RL | -0.0736796 |
| RPL14 | -0.0737011 |
| CCRN4L | -0.0737116 |
| SELO | -0.0737141 |
| TSC22D1 | -0.0737479 |
| ARSD | -0.0737505 |
| KRT71 | -0.0737542 |
| PSG4 | -0.0737581 |
| GBP7 | -0.0737641 |
| FAM120B | -0.0737645 |
| FAM27C | -0.0737884 |
| PLA2G4F | -0.0738127 |
| SLC5A7 | -0.0738155 |
| LGI1 | -0.0738250 |
| ADAM22 | -0.0738300 |
| NR5A2 | -0.0738339 |
| C9orf114 | -0.0738368 |
| DIP2B | -0.0738582 |
| SOX13 | -0.0739147 |
| CLDND2 | -0.0739252 |
| RBM27 | -0.0739444 |
| CRIP3 | -0.0739461 |
| KIF7 | -0.0739484 |
| HEATR5A | -0.0739494 |
| TXNDC17 | -0.0739576 |
| RAB21 | -0.0739706 |
| TUBGCP6 | -0.0739890 |
| BPIFB3 | -0.0739928 |
| DGKB | -0.0739948 |
| ASL | -0.0740051 |
| RIPPLY1 | -0.0740176 |
| ARIH2 | -0.0740214 |
| PTPRN | -0.0740261 |
| IDI2 | -0.0740262 |
| LRRTM2 | -0.0740450 |
| TFCP2L1 | -0.0740530 |
| G6PC3 | -0.0740621 |
| C15orf26 | -0.0740633 |
| PHKA1 | -0.0740698 |
| SLC2A8 | -0.0740727 |
| PCDHGB2 | -0.0740764 |
| TMEM248 | -0.0740770 |
| ATP1B1 | -0.0741328 |
| NEK7 | -0.0741626 |
| HSPB3 | -0.0741651 |
| LUC7L3 | -0.0741692 |
| SLC7A9 | -0.0741699 |
| RGS17 | -0.0741830 |
| ABCC6 | -0.0741891 |
| DEFB114 | -0.0741921 |
| ZNF732 | -0.0742071 |
| GRIK1 | -0.0742133 |
| CTBP2 | -0.0742450 |
| PAEP | -0.0742478 |
| HTRA3 | -0.0742545 |
| ZNF541 | -0.0742576 |
| LRRC4 | -0.0742884 |
| ARID4B | -0.0743087 |
| SPATA5 | -0.0743463 |
| CHRNB4 | -0.0743515 |
| FAM163A | -0.0743738 |
| RBCK1 | -0.0743784 |
| RASL12 | -0.0743790 |
| C4orf21 | -0.0743861 |
| PDHA2 | -0.0744036 |
| CCDC38 | -0.0744045 |
| SC5D | -0.0744316 |
| ZNRF2 | -0.0744345 |
| KLKB1 | -0.0744984 |
| ASMT | -0.0745029 |
| TMEM50A | -0.0745072 |
| NDST4 | -0.0745250 |
| ZNF493 | -0.0745386 |
| SLITRK3 | -0.0745472 |
| SERAC1 | -0.0745573 |
| USP9Y | -0.0745577 |
| SERPINA4 | -0.0745641 |
| THAP5 | -0.0745847 |
| DCAF12L1 | -0.0746073 |
| CHRNA3 | -0.0746306 |
| VSTM4 | -0.0746453 |
| KHDRBS2 | -0.0746597 |
| CNTN1 | -0.0746649 |
| COX16 | -0.0746669 |
| COX11 | -0.0746682 |
| HDAC10 | -0.0746904 |
| BPY2B | -0.0746971 |
| PLA2G2F | -0.0747083 |
| SPCS1 | -0.0747168 |
| ELAVL3 | -0.0747304 |
| HELQ | -0.0747411 |
| HNRNPLL | -0.0747496 |
| PRKAR2A | -0.0747673 |
| NPAS4 | -0.0747742 |
| GK2 | -0.0747778 |
| ZFP90 | -0.0747972 |
| NEUROD4 | -0.0747994 |
| PTCHD2 | -0.0748005 |
| TMEM261 | -0.0748050 |
| OLFM4 | -0.0748064 |
| SLC35G1 | -0.0748079 |
| FAM167A | -0.0748231 |
| EXOC3 | -0.0748394 |
| GLTSCR2 | -0.0748442 |
| ANHX | -0.0748950 |
| PPP1R15B | -0.0749067 |
| TAF1L | -0.0749086 |
| NREP | -0.0749144 |
| SYTL5 | -0.0749231 |
| FAM27E3 | -0.0749502 |
| APOL5 | -0.0749781 |
| GABPA | -0.0749793 |
| PSTK | -0.0749868 |
| FAM13C | -0.0750080 |
| ANXA13 | -0.0750112 |
| LCE1E | -0.0750126 |
| XIAP | -0.0750139 |
| ZNF610 | -0.0750203 |
| ZNF480 | -0.0750252 |
| KLHL13 | -0.0750388 |
| FAM155B | -0.0750404 |
| TAS2R20 | -0.0750455 |
| CCL27 | -0.0750523 |
| MYOZ2 | -0.0750744 |
| ANXA6 | -0.0750926 |
| RNASE11 | -0.0751096 |
| C6orf201 | -0.0751199 |
| GATA1 | -0.0751223 |
| PRL | -0.0751306 |
| TTC33 | -0.0751325 |
| CACNA1F | -0.0751455 |
| ATXN3 | -0.0751730 |
| GNRH1 | -0.0751950 |
| CLCN7 | -0.0751954 |
| TMEM242 | -0.0751973 |
| RGSL1 | -0.0752071 |
| ACADL | -0.0752119 |
| LAMB4 | -0.0752311 |
| SEMA6D | -0.0752392 |
| PDYN | -0.0752443 |
| CTAGE5 | -0.0752585 |
| VPS37C | -0.0752601 |
| GPATCH2L | -0.0752694 |
| CERCAM | -0.0752700 |
| TCP11L2 | -0.0752727 |
| IL9 | -0.0752942 |
| NLGN3 | -0.0753014 |
| HOXA11 | -0.0753079 |
| KCNK3 | -0.0753168 |
| AFM | -0.0753196 |
| C1orf189 | -0.0753448 |
| HTR5A | -0.0753820 |
| NRXN1 | -0.0753850 |
| ZNF432 | -0.0753972 |
| ZNF10 | -0.0754023 |
| ATXN10 | -0.0754142 |
| ETNPPL | -0.0754296 |
| KRT33A | -0.0754346 |
| NAT14 | -0.0754394 |
| SPATA19 | -0.0754452 |
| SORL1 | -0.0754551 |
| CDK13 | -0.0754890 |
| ALDH1A2 | -0.0755138 |
| SMG1 | -0.0755186 |
| SUV420H1 | -0.0755232 |
| TYW1 | -0.0755428 |
| PTN | -0.0755456 |
| PRSS38 | -0.0755519 |
| CCDC116 | -0.0755525 |
| RFPL4B | -0.0755587 |
| ZNF766 | -0.0755920 |
| SPATA33 | -0.0755933 |
| SYCP3 | -0.0756129 |
| HSPA4L | -0.0756375 |
| VWA5B1 | -0.0756464 |
| PNMA2 | -0.0756471 |
| SLCO6A1 | -0.0756750 |
| CFHR4 | -0.0756985 |
| VAMP4 | -0.0757168 |
| TMCC1 | -0.0757193 |
| MED19 | -0.0757205 |
| GRM1 | -0.0757338 |
| SCAP | -0.0757570 |
| SGCZ | -0.0757581 |
| AJAP1 | -0.0757585 |
| SLCO1B7 | -0.0757591 |
| PPP1R12C | -0.0757699 |
| TYRO3 | -0.0757985 |
| CDR1 | -0.0757997 |
| NDUFS8 | -0.0758281 |
| CCDC81 | -0.0758404 |
| CCDC105 | -0.0758640 |
| FAM71B | -0.0758890 |
| WDR17 | -0.0758899 |
| C1QL3 | -0.0758998 |
| TBC1D13 | -0.0759371 |
| ABCB5 | -0.0759402 |
| ZNF250 | -0.0759437 |
| LGR5 | -0.0759456 |
| PRKAB1 | -0.0759545 |
| DNAI2 | -0.0759604 |
| GPATCH8 | -0.0759679 |
| SKAP1 | -0.0759720 |
| PAX3 | -0.0759776 |
| ZNF561 | -0.0759826 |
| HOXA6 | -0.0760031 |
| PSG6 | -0.0760110 |
| ZXDC | -0.0760130 |
| ERC1 | -0.0760156 |
| DEFB103B | -0.0760257 |
| TOR1AIP1 | -0.0760289 |
| PLA2G12B | -0.0760327 |
| ITSN1 | -0.0760559 |
| ALX1 | -0.0760616 |
| UNC13C | -0.0760790 |
| SALL3 | -0.0760855 |
| PCDHGA12 | -0.0760866 |
| RAB33B | -0.0761194 |
| CGGBP1 | -0.0761265 |
| ARMC7 | -0.0761334 |
| MRPL53 | -0.0761337 |
| LHX6 | -0.0761349 |
| PRR14 | -0.0761464 |
| GRIP1 | -0.0761758 |
| KIAA1549L | -0.0761783 |
| CDHR4 | -0.0761801 |
| BDKRB2 | -0.0762026 |
| SMDT1 | -0.0762129 |
| CLRN3 | -0.0762361 |
| SENP8 | -0.0762594 |
| ECSIT | -0.0762705 |
| ST18 | -0.0762822 |
| TRIM60 | -0.0763030 |
| C14orf39 | -0.0763197 |
| HOXD12 | -0.0763284 |
| NEURL1B | -0.0763482 |
| HAL | -0.0763596 |
| PIH1D3 | -0.0763654 |
| ATP6AP1 | -0.0763671 |
| ROCK1 | -0.0763691 |
| C9orf37 | -0.0763968 |
| TAB3 | -0.0764079 |
| TM4SF20 | -0.0764220 |
| TNS1 | -0.0764239 |
| ATP6V0E2 | -0.0764598 |
| SEPT11 | -0.0764640 |
| CCDC57 | -0.0764782 |
| SLC35G5 | -0.0764901 |
| POLG2 | -0.0765135 |
| ZBTB40 | -0.0765336 |
| RSL24D1 | -0.0765486 |
| MED31 | -0.0765570 |
| RHOT1 | -0.0765779 |
| ATAD1 | -0.0765781 |
| MYH8 | -0.0766159 |
| SVIP | -0.0766306 |
| KCNQ1 | -0.0766408 |
| DDX47 | -0.0766429 |
| CDKN2AIP | -0.0766697 |
| MEGF9 | -0.0766752 |
| CELA3B | -0.0766767 |
| DUS4L | -0.0766904 |
| BANF2 | -0.0766944 |
| ZMPSTE24 | -0.0766970 |
| OXLD1 | -0.0766991 |
| ZNF517 | -0.0767216 |
| OR1A1 | -0.0767265 |
| SETD2 | -0.0767484 |
| GAS2 | -0.0767504 |
| GGNBP2 | -0.0767535 |
| PAFAH1B3 | -0.0767542 |
| POLR2E | -0.0767568 |
| CCDC7 | -0.0767613 |
| MED12L | -0.0767634 |
| KIAA0895L | -0.0767977 |
| C10orf137 | -0.0768067 |
| AGBL4 | -0.0768303 |
| THAP3 | -0.0768488 |
| LCAT | -0.0768701 |
| PPIL6 | -0.0768896 |
| OTUD6B | -0.0769039 |
| ZBTB3 | -0.0769172 |
| ALS2 | -0.0769178 |
| OR7D2 | -0.0769492 |
| CUBN | -0.0769506 |
| CRELD1 | -0.0769579 |
| MTHFS | -0.0769615 |
| FAM217B | -0.0769747 |
| ALLC | -0.0769875 |
| TUBG2 | -0.0769940 |
| AQP6 | -0.0769998 |
| ESD | -0.0770155 |
| CNTN3 | -0.0770184 |
| WIPI2 | -0.0770409 |
| ARL6IP1 | -0.0770514 |
| PRKG2 | -0.0770623 |
| BRSK1 | -0.0770623 |
| CAPN11 | -0.0770707 |
| MKS1 | -0.0770771 |
| SPDYE3 | -0.0770860 |
| UBE2K | -0.0770862 |
| TTC14 | -0.0771202 |
| MGAT5B | -0.0771291 |
| ZNF333 | -0.0771341 |
| GPR116 | -0.0771350 |
| PRMT7 | -0.0771430 |
| CD34 | -0.0771771 |
| SYNPR | -0.0771827 |
| SFXN3 | -0.0772245 |
| ZFC3H1 | -0.0772432 |
| PPP3CA | -0.0772479 |
| CCDC53 | -0.0772534 |
| LGALS16 | -0.0772662 |
| TAS2R10 | -0.0772916 |
| SLC9A5 | -0.0773001 |
| ZDHHC15 | -0.0773089 |
| DACT1 | -0.0773173 |
| MLLT4 | -0.0773359 |
| SLC25A40 | -0.0773828 |
| SSX1 | -0.0773897 |
| LINC00955 | -0.0773979 |
| CDADC1 | -0.0774012 |
| CABP1 | -0.0774142 |
| TMEM150A | -0.0774174 |
| RSBN1L | -0.0774379 |
| MBTPS1 | -0.0774408 |
| TSNARE1 | -0.0774411 |
| BEX4 | -0.0774426 |
| ZNF224 | -0.0774443 |
| TMEM198 | -0.0774488 |
| C1orf111 | -0.0774868 |
| TMPRSS11D | -0.0774948 |
| DNTT | -0.0775259 |
| DIP2C | -0.0775513 |
| DNAJC30 | -0.0775556 |
| SOGA3 | -0.0775712 |
| RAPGEF3 | -0.0775733 |
| C17orf104 | -0.0776121 |
| LGI4 | -0.0776139 |
| C11orf1 | -0.0776913 |
| TLL2 | -0.0777112 |
| C19orf44 | -0.0777345 |
| C2orf78 | -0.0777646 |
| GEMIN5 | -0.0777654 |
| C11orf30 | -0.0777711 |
| PRKAR1A | -0.0777760 |
| PLCB1 | -0.0777876 |
| PROZ | -0.0778096 |
| SLC2A10 | -0.0778234 |
| LMLN | -0.0778272 |
| DPCD | -0.0778304 |
| ZBBX | -0.0778709 |
| FLRT2 | -0.0778730 |
| PDILT | -0.0778930 |
| PCSK2 | -0.0779041 |
| CRBN | -0.0779043 |
| DNAH6 | -0.0779130 |
| PNLIP | -0.0779177 |
| CT47B1 | -0.0779322 |
| UGT1A8 | -0.0779371 |
| SLC25A29 | -0.0779453 |
| ORC4 | -0.0779534 |
| TACC2 | -0.0779741 |
| PWWP2A | -0.0779848 |
| FRG2 | -0.0779908 |
| WDR33 | -0.0779980 |
| SPAG1 | -0.0779986 |
| ZMYM2 | -0.0780039 |
| MRPL42 | -0.0780040 |
| BCKDHA | -0.0780044 |
| PARK7 | -0.0780271 |
| SLC2A4 | -0.0780544 |
| TSPAN12 | -0.0780561 |
| ATP1B4 | -0.0780689 |
| NUDT9 | -0.0780747 |
| DUSP21 | -0.0781206 |
| GOLGA4 | -0.0781207 |
| C8B | -0.0781290 |
| RAD21 | -0.0781378 |
| MRPL30 | -0.0781449 |
| KLHL1 | -0.0782252 |
| NDST1 | -0.0782296 |
| C7orf57 | -0.0782653 |
| ZNF616 | -0.0782653 |
| SIGLECL1 | -0.0782915 |
| GRAMD1A | -0.0782961 |
| PFKFB2 | -0.0782962 |
| DNASE1 | -0.0782966 |
| TBCE | -0.0783101 |
| PORCN | -0.0783111 |
| PLA2G1B | -0.0783184 |
| LTBP3 | -0.0783188 |
| FGF3 | -0.0783248 |
| FAM117B | -0.0783316 |
| BNIP3L | -0.0783580 |
| VWC2L | -0.0783599 |
| GNAT1 | -0.0783610 |
| DHX30 | -0.0783742 |
| CRB1 | -0.0783948 |
| HIST1H4F | -0.0784127 |
| AKT1S1 | -0.0784417 |
| INSL5 | -0.0784852 |
| DNAH12 | -0.0785045 |
| ZNF486 | -0.0785240 |
| OTX2 | -0.0785244 |
| ZBTB26 | -0.0785267 |
| PRG4 | -0.0785303 |
| LSM11 | -0.0785459 |
| TFAP4 | -0.0785732 |
| CLCN3 | -0.0785893 |
| SPDYE1 | -0.0786197 |
| FAM71F2 | -0.0786444 |
| SEMA4C | -0.0786471 |
| TMPRSS11F | -0.0786765 |
| TECRL | -0.0786979 |
| CAMTA2 | -0.0787042 |
| SPRR4 | -0.0787257 |
| RBPMS | -0.0787607 |
| ACTR8 | -0.0787748 |
| GPC4 | -0.0787887 |
| SPOCD1 | -0.0788046 |
| ZNF490 | -0.0788136 |
| ANKRD18A | -0.0788304 |
| FGD6 | -0.0788358 |
| ABCC9 | -0.0788402 |
| LAYN | -0.0788416 |
| RPUSD2 | -0.0788423 |
| SIDT2 | -0.0788654 |
| ARMCX5 | -0.0788670 |
| ZNHIT3 | -0.0788914 |
| C9orf84 | -0.0789249 |
| TTC17 | -0.0789455 |
| RPL13A | -0.0789656 |
| CETN2 | -0.0789717 |
| RBMY1E | -0.0789862 |
| ANO8 | -0.0789886 |
| UNC80 | -0.0789944 |
| BMP2 | -0.0789950 |
| MGAT4C | -0.0790028 |
| CHMP4A | -0.0790048 |
| DLEC1 | -0.0790448 |
| ZBTB37 | -0.0790518 |
| METTL2B | -0.0790531 |
| TLDC2 | -0.0790687 |
| TCEA1 | -0.0790741 |
| OLFM3 | -0.0790910 |
| SYT5 | -0.0791091 |
| LMBR1 | -0.0791108 |
| ADGB | -0.0791161 |
| WRB | -0.0791290 |
| C3orf35 | -0.0791318 |
| HHATL | -0.0791480 |
| NTNG1 | -0.0791783 |
| CCDC84 | -0.0791895 |
| IGFBP6 | -0.0791909 |
| FAM81A | -0.0791964 |
| ARHGEF37 | -0.0792037 |
| C18orf54 | -0.0792386 |
| CCDC135 | -0.0792627 |
| ISL1 | -0.0792855 |
| GABRA5 | -0.0793024 |
| PPP1R3B | -0.0793075 |
| SOX5 | -0.0793169 |
| AKR1C3 | -0.0793212 |
| HBD | -0.0793374 |
| ABHD10 | -0.0793404 |
| AFF2 | -0.0793685 |
| ZNF416 | -0.0794155 |
| BTD | -0.0794409 |
| GRIN2A | -0.0794513 |
| CAAP1 | -0.0794545 |
| NPY2R | -0.0794847 |
| HEATR2 | -0.0794932 |
| RPL8 | -0.0794989 |
| WISP1 | -0.0795447 |
| TTC26 | -0.0795567 |
| NPCDR1 | -0.0795915 |
| GRID1 | -0.0795996 |
| RPL28 | -0.0796026 |
| DPP9 | -0.0796159 |
| TTC19 | -0.0796259 |
| MYH13 | -0.0796424 |
| TM2D2 | -0.0796551 |
| C1orf109 | -0.0796894 |
| PCDHGA5 | -0.0797192 |
| GJA4 | -0.0797452 |
| DCAF6 | -0.0797460 |
| KIAA1211L | -0.0797500 |
| ZNF653 | -0.0797514 |
| MAP2K7 | -0.0797695 |
| ATE1 | -0.0797875 |
| ZC3H10 | -0.0798162 |
| ART5 | -0.0798320 |
| VWA3A | -0.0798351 |
| ZNF492 | -0.0798370 |
| PHRF1 | -0.0798877 |
| RPAP1 | -0.0798878 |
| BCKDHB | -0.0799074 |
| KLHL11 | -0.0799364 |
| ACSM5 | -0.0799393 |
| THBS2 | -0.0799400 |
| CCDC78 | -0.0799486 |
| C20orf194 | -0.0800012 |
| FAM26D | -0.0800289 |
| ACAT1 | -0.0800371 |
| MROH2B | -0.0800451 |
| PIGP | -0.0800795 |
| MYO9A | -0.0800861 |
| RBM6 | -0.0801479 |
| C9orf3 | -0.0801640 |
| TRIM3 | -0.0801660 |
| ALMS1 | -0.0801699 |
| FOSB | -0.0801829 |
| IL22 | -0.0801831 |
| CASKIN1 | -0.0801837 |
| NNT | -0.0801975 |
| ANKRD30BL | -0.0802404 |
| CFHR2 | -0.0802842 |
| FNBP4 | -0.0802860 |
| BDKRB1 | -0.0803316 |
| TBX22 | -0.0803462 |
| SPPL2C | -0.0803544 |
| PCDHGB7 | -0.0803618 |
| COL16A1 | -0.0803660 |
| RNPC3 | -0.0803730 |
| TRPM8 | -0.0803765 |
| DNAJB8 | -0.0803794 |
| ZNF835 | -0.0804103 |
| SLCO1C1 | -0.0804131 |
| THEM4 | -0.0804330 |
| SLC25A42 | -0.0804526 |
| DUSP27 | -0.0804907 |
| RRP8 | -0.0805021 |
| TMEM87B | -0.0805046 |
| MRPL21 | -0.0805092 |
| ZNF700 | -0.0805115 |
| BGLAP | -0.0805416 |
| APITD1 | -0.0805419 |
| TCEB3C | -0.0805437 |
| SFRP5 | -0.0805451 |
| BARHL2 | -0.0805594 |
| NHP2 | -0.0805607 |
| ARAP3 | -0.0805862 |
| HYDIN | -0.0805918 |
| RAB11B | -0.0806069 |
| EPHA8 | -0.0806310 |
| GSG1 | -0.0806404 |
| C20orf202 | -0.0806457 |
| HIST1H4K | -0.0806545 |
| SEPSECS | -0.0806580 |
| AIMP1 | -0.0806661 |
| PNPLA1 | -0.0806691 |
| SETD1B | -0.0806719 |
| ELTD1 | -0.0806844 |
| ZNF680 | -0.0807083 |
| BPTF | -0.0807430 |
| KRCC1 | -0.0807639 |
| RIC8A | -0.0807720 |
| PAN3 | -0.0807814 |
| ZNF423 | -0.0807835 |
| PPP3CB | -0.0807874 |
| GOLGA8K | -0.0807918 |
| WLS | -0.0808249 |
| RBMXL3 | -0.0808291 |
| ZNF169 | -0.0808552 |
| INO80E | -0.0808966 |
| C1orf122 | -0.0808975 |
| ZNF134 | -0.0809116 |
| PDE12 | -0.0809117 |
| NPW | -0.0809158 |
| POLB | -0.0809365 |
| SMIM15 | -0.0809452 |
| ADARB2 | -0.0809538 |
| NLRP13 | -0.0809899 |
| SERPINI2 | -0.0810089 |
| TCP10L | -0.0810146 |
| C19orf70 | -0.0810280 |
| ZSCAN30 | -0.0810489 |
| NDUFA10 | -0.0810634 |
| DLX3 | -0.0810656 |
| C20orf166 | -0.0810833 |
| NRIP2 | -0.0810889 |
| MAEL | -0.0810902 |
| LGALS12 | -0.0810927 |
| ANKIB1 | -0.0811036 |
| ARMC12 | -0.0811104 |
| C20orf26 | -0.0811473 |
| GRIN3B | -0.0811566 |
| RPS6KL1 | -0.0811568 |
| CCDC63 | -0.0811954 |
| EPHX1 | -0.0811957 |
| PRH2 | -0.0812012 |
| WNT16 | -0.0812163 |
| TMPRSS15 | -0.0812308 |
| MYH10 | -0.0812353 |
| SLC24A2 | -0.0812646 |
| NDUFAF2 | -0.0812681 |
| ETF1 | -0.0812755 |
| PDS5A | -0.0812841 |
| YWHAB | -0.0812857 |
| COL6A1 | -0.0812857 |
| SP2 | -0.0812898 |
| TBC1D3C | -0.0812969 |
| C21orf54 | -0.0813137 |
| SYCN | -0.0813419 |
| ANKRD26 | -0.0813505 |
| SNX9 | -0.0813632 |
| PRDM7 | -0.0813691 |
| FBN1 | -0.0813696 |
| PCDP1 | -0.0813702 |
| CREBRF | -0.0813728 |
| TEX33 | -0.0813829 |
| DNAJC25 | -0.0813896 |
| BEST3 | -0.0813950 |
| SDCCAG8 | -0.0814106 |
| HTN1 | -0.0814254 |
| TMPRSS11B | -0.0814507 |
| HIC1 | -0.0814584 |
| SCG2 | -0.0815243 |
| NFIX | -0.0815278 |
| MYOM1 | -0.0815492 |
| CYP2E1 | -0.0815904 |
| LRRTM4 | -0.0815957 |
| DCAF8 | -0.0816020 |
| CLCA4 | -0.0816175 |
| AP3B2 | -0.0816227 |
| RXRA | -0.0816265 |
| CASQ2 | -0.0816282 |
| EFCAB13 | -0.0816290 |
| ZNF808 | -0.0816416 |
| TUBGCP5 | -0.0816558 |
| XAB2 | -0.0816578 |
| FGF14 | -0.0816592 |
| TMPRSS11A | -0.0816653 |
| ZNF165 | -0.0816866 |
| RPRD2 | -0.0816871 |
| TP53 | -0.0816893 |
| RGS9 | -0.0817146 |
| ZNF268 | -0.0817242 |
| MYO1B | -0.0817426 |
| TTC16 | -0.0817427 |
| CDK10 | -0.0817558 |
| CTXN2 | -0.0817607 |
| PCDHB15 | -0.0817690 |
| DGKE | -0.0817774 |
| CNGB3 | -0.0817774 |
| ALS2CR11 | -0.0818066 |
| ABCB8 | -0.0818842 |
| DCAKD | -0.0818862 |
| ZNF626 | -0.0818949 |
| LECT2 | -0.0819228 |
| HOXA7 | -0.0819571 |
| FBXW4 | -0.0819695 |
| ATF1 | -0.0819809 |
| BMP8A | -0.0819830 |
| AS3MT | -0.0820196 |
| DLL4 | -0.0820213 |
| YAF2 | -0.0820246 |
| ZNF429 | -0.0820384 |
| AZGP1 | -0.0820407 |
| VEZT | -0.0820754 |
| FSTL5 | -0.0820803 |
| IPO8 | -0.0820881 |
| CCDC65 | -0.0820893 |
| TBX20 | -0.0820957 |
| ADAMTS20 | -0.0821058 |
| MSANTD2 | -0.0821172 |
| ATP2B2 | -0.0821229 |
| PPP1R14D | -0.0821247 |
| ZNF530 | -0.0821371 |
| COPS5 | -0.0821498 |
| SH3GL2 | -0.0821532 |
| RPL26L1 | -0.0821588 |
| SLC25A4 | -0.0821620 |
| CYYR1 | -0.0821676 |
| ZNF99 | -0.0821847 |
| USE1 | -0.0822002 |
| C9orf66 | -0.0822013 |
| ZNF697 | -0.0822032 |
| TEAD1 | -0.0822168 |
| VPS37A | -0.0822176 |
| DZIP1L | -0.0822549 |
| FBXL22 | -0.0823125 |
| GCNT4 | -0.0823508 |
| C10orf67 | -0.0823654 |
| PRDM5 | -0.0823687 |
| ZNF431 | -0.0823691 |
| SMN2 | -0.0823732 |
| RPL29 | -0.0823767 |
| TCEB3B | -0.0824001 |
| NEUROD1 | -0.0824043 |
| C17orf67 | -0.0824089 |
| MED29 | -0.0824240 |
| USP29 | -0.0824528 |
| PCLO | -0.0824567 |
| CREG2 | -0.0824820 |
| TNNI3K | -0.0824828 |
| TMEM143 | -0.0825195 |
| HECTD4 | -0.0825307 |
| SCN4A | -0.0825517 |
| CDC20B | -0.0825777 |
| ZNF551 | -0.0825950 |
| C1orf145 | -0.0826150 |
| MADD | -0.0826269 |
| KCNJ8 | -0.0826324 |
| LRCH2 | -0.0826698 |
| CNRIP1 | -0.0827084 |
| ZNF827 | -0.0827241 |
| ARPC4-TTLL3 | -0.0827353 |
| SEPHS2 | -0.0827421 |
| ZNF449 | -0.0827797 |
| AQP1 | -0.0827882 |
| CES2 | -0.0827968 |
| TARBP2 | -0.0828311 |
| MGEA5 | -0.0828393 |
| TULP4 | -0.0828557 |
| CADPS | -0.0829050 |
| HFM1 | -0.0829226 |
| ARHGEF12 | -0.0829300 |
| TEX28 | -0.0829341 |
| TSC1 | -0.0829347 |
| FAM86C1 | -0.0829414 |
| ECI2 | -0.0829742 |
| ESPNL | -0.0829922 |
| PAWR | -0.0830178 |
| FIS1 | -0.0830195 |
| PCDHGB6 | -0.0830196 |
| ADAMTS16 | -0.0830232 |
| C3orf36 | -0.0830284 |
| SIGLEC6 | -0.0830288 |
| PRUNE2 | -0.0830437 |
| LIPT2 | -0.0830632 |
| MEP1B | -0.0830696 |
| NSRP1 | -0.0831254 |
| MAB21L1 | -0.0831673 |
| F8 | -0.0831786 |
| CYP4F2 | -0.0832028 |
| SLC7A3 | -0.0832033 |
| KLF10 | -0.0832111 |
| PARP16 | -0.0832167 |
| FAM120C | -0.0832671 |
| COL11A1 | -0.0832844 |
| SLC38A4 | -0.0832845 |
| RAB5B | -0.0832945 |
| DHX35 | -0.0833256 |
| NUTM2B | -0.0833265 |
| GLUD2 | -0.0833377 |
| GJB1 | -0.0833382 |
| SCAPER | -0.0833523 |
| RAD9B | -0.0833678 |
| SLC8A3 | -0.0833765 |
| C21orf88 | -0.0833884 |
| NBPF10 | -0.0833897 |
| TJP1 | -0.0833919 |
| CNST | -0.0834007 |
| KRTAP5-8 | -0.0834244 |
| LSMEM1 | -0.0834338 |
| BEND7 | -0.0834700 |
| RBM46 | -0.0834764 |
| ING5 | -0.0834958 |
| SUCO | -0.0835240 |
| IREB2 | -0.0835391 |
| PAPD5 | -0.0835455 |
| FAM160A2 | -0.0835749 |
| SALL4 | -0.0835832 |
| FAM134C | -0.0836314 |
| EPHA6 | -0.0836358 |
| CMA1 | -0.0836536 |
| UNC5B | -0.0836602 |
| GLYAT | -0.0836680 |
| TAS2R46 | -0.0836691 |
| HBM | -0.0836792 |
| WFDC13 | -0.0836998 |
| ETNK1 | -0.0837156 |
| ABTB1 | -0.0837189 |
| HEATR4 | -0.0837769 |
| VN1R1 | -0.0838183 |
| SLC9A2 | -0.0838243 |
| TDRD3 | -0.0838412 |
| GJA3 | -0.0838714 |
| PTPRD | -0.0838894 |
| LEPREL1 | -0.0838925 |
| FRMPD4 | -0.0838960 |
| ITIH6 | -0.0838982 |
| LRFN5 | -0.0839065 |
| SLC25A16 | -0.0839351 |
| PCDHGB3 | -0.0839582 |
| POLM | -0.0839624 |
| UBALD1 | -0.0839927 |
| AHI1 | -0.0839981 |
| ZNF221 | -0.0840075 |
| GNPAT | -0.0840183 |
| PRRX1 | -0.0840241 |
| CCDC51 | -0.0840319 |
| C11orf74 | -0.0840714 |
| ANO2 | -0.0841018 |
| STYXL1 | -0.0841247 |
| CTXN3 | -0.0841335 |
| EIF3G | -0.0841344 |
| NAA60 | -0.0841529 |
| PHYKPL | -0.0841569 |
| DPP10 | -0.0841693 |
| RUFY1 | -0.0841697 |
| ADAMTS15 | -0.0841760 |
| CHM | -0.0841795 |
| GNGT1 | -0.0841914 |
| CDX4 | -0.0841984 |
| ENOPH1 | -0.0842356 |
| CHSY3 | -0.0842555 |
| ANO3 | -0.0842646 |
| C2orf16 | -0.0842992 |
| LRRC27 | -0.0843121 |
| C8orf12 | -0.0843404 |
| FILIP1 | -0.0843584 |
| MGAT5 | -0.0843741 |
| UBXN6 | -0.0843942 |
| PCDHA9 | -0.0844056 |
| CTH | -0.0844081 |
| ANKRD6 | -0.0844117 |
| PCNP | -0.0844165 |
| FAM222A | -0.0844542 |
| MYO18B | -0.0844577 |
| SOGA1 | -0.0844641 |
| GTPBP3 | -0.0844796 |
| GRIN2B | -0.0844810 |
| FRMD7 | -0.0844896 |
| CCDC180 | -0.0845388 |
| ZNF285 | -0.0845750 |
| SYF2 | -0.0845798 |
| GRASP | -0.0845835 |
| CLCF1 | -0.0846317 |
| TRDN | -0.0846624 |
| DCTPP1 | -0.0847218 |
| ABCB9 | -0.0847223 |
| CNTD2 | -0.0847389 |
| VPS4B | -0.0847414 |
| DOK6 | -0.0847475 |
| BNC1 | -0.0847552 |
| NADK2 | -0.0847553 |
| TMED7 | -0.0847700 |
| CSRP2BP | -0.0848054 |
| NCOR1 | -0.0848087 |
| ATP6V0C | -0.0848106 |
| METTL21A | -0.0848260 |
| PTPN20B | -0.0848265 |
| FBXL17 | -0.0848315 |
| CLCA1 | -0.0848716 |
| SLC25A20 | -0.0848825 |
| ABCD4 | -0.0848847 |
| MAPK12 | -0.0848886 |
| C6orf120 | -0.0849020 |
| TEKT3 | -0.0849044 |
| CCDC181 | -0.0849081 |
| SVOP | -0.0849166 |
| DNPEP | -0.0849596 |
| CYP4F3 | -0.0849602 |
| FCHO2 | -0.0849628 |
| SWI5 | -0.0849632 |
| ADAM11 | -0.0849661 |
| CCDC39 | -0.0849673 |
| ZMIZ1 | -0.0849733 |
| TUFM | -0.0849884 |
| ZC3H11A | -0.0849891 |
| NCOA2 | -0.0850006 |
| INSM1 | -0.0850124 |
| UBE2D4 | -0.0850356 |
| DYDC1 | -0.0850509 |
| SPNS1 | -0.0850509 |
| CA5A | -0.0850682 |
| TNP1 | -0.0850885 |
| SMIM4 | -0.0850940 |
| AAAS | -0.0851006 |
| RFK | -0.0851103 |
| PLSCR2 | -0.0851180 |
| KIAA1644 | -0.0851637 |
| FUK | -0.0851987 |
| ECT2L | -0.0852278 |
| ABRA | -0.0852312 |
| TRAPPC5 | -0.0852469 |
| GIGYF1 | -0.0852557 |
| INTS4 | -0.0852769 |
| EPM2AIP1 | -0.0852785 |
| CNOT2 | -0.0853268 |
| LINC00935 | -0.0853300 |
| UGGT2 | -0.0853372 |
| SIL1 | -0.0853772 |
| ANP32A | -0.0853801 |
| ZMYM1 | -0.0853898 |
| PPFIA3 | -0.0853901 |
| TP53AIP1 | -0.0854043 |
| FEM1C | -0.0854122 |
| AMH | -0.0854221 |
| ATP6V0D2 | -0.0854344 |
| MRPL28 | -0.0854477 |
| RABL2A | -0.0854513 |
| TOMM20 | -0.0854545 |
| MYLPF | -0.0854604 |
| SRXN1 | -0.0854604 |
| ZNF347 | -0.0854767 |
| RPA3 | -0.0855010 |
| EPN1 | -0.0855045 |
| SNX4 | -0.0855085 |
| KRT12 | -0.0855142 |
| VAT1 | -0.0855383 |
| KLHL20 | -0.0855499 |
| RBBP7 | -0.0855628 |
| PEX6 | -0.0856115 |
| NOTCH3 | -0.0856304 |
| C20orf112 | -0.0856553 |
| NOVA2 | -0.0856618 |
| PRR13 | -0.0856638 |
| S1PR3 | -0.0856828 |
| PTPN1 | -0.0856865 |
| ZNF550 | -0.0857339 |
| CC2D1A | -0.0857434 |
| MAU2 | -0.0857442 |
| SESN3 | -0.0857482 |
| SLC43A1 | -0.0857488 |
| H3F3B | -0.0857538 |
| FRMD5 | -0.0857571 |
| ENOSF1 | -0.0857877 |
| ZMYM6 | -0.0857978 |
| DPP7 | -0.0858109 |
| SLC25A27 | -0.0858111 |
| KCNA4 | -0.0858289 |
| ARFGAP2 | -0.0858328 |
| NBPF14 | -0.0858529 |
| ZNF343 | -0.0858576 |
| DPCR1 | -0.0858745 |
| SMIM6 | -0.0858843 |
| ANKRD45 | -0.0859364 |
| KCTD13 | -0.0859408 |
| NPRL3 | -0.0859445 |
| TPH1 | -0.0859448 |
| FAP | -0.0859959 |
| ZNF107 | -0.0860108 |
| ISLR | -0.0860150 |
| ATP6V1G3 | -0.0860476 |
| HSD17B3 | -0.0860755 |
| SV2B | -0.0860762 |
| ARHGAP20 | -0.0860828 |
| PDZRN4 | -0.0860846 |
| PNKP | -0.0860918 |
| METTL21B | -0.0861074 |
| DHX15 | -0.0861143 |
| EBF1 | -0.0861325 |
| TTR | -0.0861693 |
| MYOT | -0.0861700 |
| C14orf105 | -0.0861709 |
| C19orf24 | -0.0861862 |
| AP1G2 | -0.0862449 |
| SPACA5 | -0.0862581 |
| ZNF707 | -0.0862716 |
| RARS | -0.0862820 |
| MMAB | -0.0863078 |
| ADH1B | -0.0863295 |
| GPBP1 | -0.0863340 |
| ZNF585A | -0.0863597 |
| MYL10 | -0.0864103 |
| TEX38 | -0.0864157 |
| IMPA1 | -0.0864425 |
| RBM39 | -0.0864617 |
| KLC3 | -0.0864830 |
| GRPEL1 | -0.0864885 |
| CCDC43 | -0.0865085 |
| BBS12 | -0.0865152 |
| TLE6 | -0.0865157 |
| ZFP69 | -0.0865165 |
| RABGEF1 | -0.0865190 |
| MYH7B | -0.0865544 |
| ARL15 | -0.0865627 |
| SPATA9 | -0.0865700 |
| DOK1 | -0.0865705 |
| SRRM4 | -0.0865777 |
| RBAK | -0.0865932 |
| RASL10B | -0.0866027 |
| CABS1 | -0.0866085 |
| TAF1 | -0.0866182 |
| SREK1IP1 | -0.0866194 |
| RSBN1 | -0.0866334 |
| PCGF5 | -0.0866351 |
| ZNF594 | -0.0866576 |
| RGAG4 | -0.0866647 |
| GOLGA8O | -0.0866737 |
| CCSER1 | -0.0866762 |
| ALDH4A1 | -0.0866787 |
| CCDC89 | -0.0866819 |
| DDX25 | -0.0866978 |
| CDC23 | -0.0867258 |
| ANKUB1 | -0.0867294 |
| SLC22A16 | -0.0867572 |
| CEP63 | -0.0867707 |
| MAFK | -0.0868390 |
| WDR20 | -0.0868566 |
| FAM227B | -0.0868606 |
| UBE2N | -0.0869546 |
| UBTF | -0.0869706 |
| LYSMD1 | -0.0869952 |
| WSCD1 | -0.0869987 |
| HIST1H2AC | -0.0870044 |
| CNTN4 | -0.0870116 |
| ZNF138 | -0.0870141 |
| SLC25A22 | -0.0870256 |
| RBL2 | -0.0870447 |
| C16orf71 | -0.0870560 |
| GPC5 | -0.0870708 |
| CTNNA1 | -0.0870760 |
| AGXT | -0.0870830 |
| PHC1 | -0.0870897 |
| VSIG10L | -0.0871231 |
| ZNF20 | -0.0871243 |
| PGC | -0.0871246 |
| CHRNB2 | -0.0871260 |
| GUF1 | -0.0871268 |
| SAP30L | -0.0871315 |
| DCUN1D2 | -0.0871362 |
| GALNTL5 | -0.0871760 |
| CABLES1 | -0.0872072 |
| DAND5 | -0.0872175 |
| ZNF687 | -0.0872418 |
| GNG10 | -0.0872683 |
| WDR13 | -0.0872736 |
| NAA20 | -0.0872829 |
| CCL28 | -0.0872838 |
| GALNT9 | -0.0872936 |
| ZNF701 | -0.0872998 |
| BCAM | -0.0873014 |
| MOGAT1 | -0.0873292 |
| GIPC2 | -0.0873307 |
| KRTAP12-2 | -0.0873501 |
| EIF2AK1 | -0.0873805 |
| C14orf37 | -0.0874011 |
| LRP2BP | -0.0874140 |
| CD99L2 | -0.0874162 |
| PRKD1 | -0.0874203 |
| DKK4 | -0.0874462 |
| MFAP3 | -0.0874670 |
| UBP1 | -0.0875102 |
| DDX59 | -0.0875479 |
| S100Z | -0.0875647 |
| ZACN | -0.0875706 |
| IFNA6 | -0.0875709 |
| ZNF43 | -0.0876059 |
| KCTD9 | -0.0876101 |
| USHBP1 | -0.0876693 |
| CAV3 | -0.0876896 |
| ADAP1 | -0.0877231 |
| FAM153B | -0.0877515 |
| C1orf233 | -0.0877596 |
| LRRCC1 | -0.0877815 |
| C17orf70 | -0.0877848 |
| CDH11 | -0.0877850 |
| RAPGEF4 | -0.0877940 |
| ZNF599 | -0.0878086 |
| WDR36 | -0.0878087 |
| FBXW9 | -0.0878166 |
| CDH13 | -0.0878437 |
| SLC16A4 | -0.0878482 |
| HYAL3 | -0.0878500 |
| OVOL1 | -0.0878670 |
| NUP62CL | -0.0878786 |
| SRGAP3 | -0.0879013 |
| PHTF1 | -0.0879197 |
| ZNF90 | -0.0879506 |
| KIAA1217 | -0.0879507 |
| CAMKV | -0.0879733 |
| MRM1 | -0.0880098 |
| KCNC3 | -0.0880212 |
| STK3 | -0.0880220 |
| EIF1B | -0.0880280 |
| INTS2 | -0.0880312 |
| KCTD21 | -0.0880346 |
| RIMS1 | -0.0880367 |
| WNT8B | -0.0880476 |
| SLC39A5 | -0.0880664 |
| C4orf19 | -0.0880711 |
| RSPH10B | -0.0880913 |
| C12orf43 | -0.0880922 |
| PARVA | -0.0880991 |
| GPR27 | -0.0881085 |
| CABP7 | -0.0881133 |
| RNF180 | -0.0881206 |
| SAGE1 | -0.0881215 |
| ZNF19 | -0.0881655 |
| DYNC1LI1 | -0.0881814 |
| ZNF443 | -0.0882225 |
| CCAR2 | -0.0882805 |
| INO80 | -0.0882882 |
| SLC10A2 | -0.0882897 |
| PAK7 | -0.0883655 |
| MMP26 | -0.0883745 |
| ZSWIM1 | -0.0883864 |
| ACSBG1 | -0.0884313 |
| ENTPD5 | -0.0884331 |
| LCORL | -0.0884362 |
| POGLUT1 | -0.0884426 |
| MRO | -0.0884485 |
| FABP12 | -0.0884893 |
| CYP20A1 | -0.0885134 |
| CRIM1 | -0.0885148 |
| USP30 | -0.0885279 |
| HRAS | -0.0885478 |
| NAPEPLD | -0.0885576 |
| ZNF213 | -0.0886327 |
| SEMA6A | -0.0886332 |
| MSS51 | -0.0886367 |
| DNM1L | -0.0886719 |
| DMRT2 | -0.0886755 |
| ABCA8 | -0.0886779 |
| UBFD1 | -0.0886825 |
| TRNAU1AP | -0.0886859 |
| NECAP1 | -0.0887477 |
| USP40 | -0.0887604 |
| VARS2 | -0.0887759 |
| FAM189A1 | -0.0888006 |
| PDE6C | -0.0888326 |
| UBQLNL | -0.0888395 |
| TSPAN3 | -0.0888452 |
| KIAA1430 | -0.0888507 |
| CELSR3 | -0.0888508 |
| TEKT1 | -0.0888613 |
| BAD | -0.0888848 |
| FAM19A5 | -0.0888910 |
| UNC5CL | -0.0889769 |
| AEBP2 | -0.0889955 |
| CCDC58 | -0.0890641 |
| NR1I2 | -0.0890890 |
| LARS | -0.0890975 |
| SUCLG2 | -0.0891429 |
| APH1B | -0.0891461 |
| ORAI3 | -0.0891507 |
| HSD17B7 | -0.0891580 |
| ZNF546 | -0.0891836 |
| C9orf43 | -0.0891878 |
| ZNF790 | -0.0891980 |
| RAG1 | -0.0892033 |
| GRM8 | -0.0892749 |
| AQP4 | -0.0892900 |
| LAMTOR2 | -0.0893093 |
| PPCS | -0.0893163 |
| APBB1 | -0.0893190 |
| COA4 | -0.0893472 |
| THOP1 | -0.0893504 |
| ADAM9 | -0.0893537 |
| CSRNP3 | -0.0893653 |
| ELMSAN1 | -0.0893673 |
| LIN54 | -0.0893973 |
| WNK2 | -0.0894056 |
| FZD4 | -0.0894195 |
| CCNT1 | -0.0894435 |
| GGA2 | -0.0894601 |
| SMYD1 | -0.0894623 |
| GPAA1 | -0.0894800 |
| ABCA10 | -0.0894904 |
| EIF4A2 | -0.0895005 |
| RAVER2 | -0.0895296 |
| NODAL | -0.0895356 |
| LRPPRC | -0.0895692 |
| EVI5 | -0.0895988 |
| PCDH10 | -0.0896030 |
| SEMG2 | -0.0896032 |
| SLC9A1 | -0.0896170 |
| EFNB1 | -0.0896204 |
| HARS2 | -0.0896206 |
| ARSK | -0.0896217 |
| ATRX | -0.0896272 |
| SCLY | -0.0896486 |
| GALP | -0.0896647 |
| OBSCN | -0.0897001 |
| CUX1 | -0.0897522 |
| KDM6A | -0.0897733 |
| BTBD8 | -0.0898041 |
| SCAMP5 | -0.0898123 |
| ZC3H3 | -0.0898638 |
| DENND5A | -0.0898761 |
| FAM73B | -0.0898967 |
| TIE1 | -0.0899155 |
| MAPK8IP1 | -0.0899262 |
| IL26 | -0.0899297 |
| RPL41 | -0.0899991 |
| FMR1NB | -0.0901024 |
| C15orf43 | -0.0901244 |
| PFAS | -0.0901245 |
| DDX4 | -0.0901302 |
| PELI2 | -0.0901501 |
| TTC9B | -0.0901513 |
| KAT8 | -0.0901803 |
| EXOC1 | -0.0901994 |
| GRHL2 | -0.0902144 |
| ZFP30 | -0.0902199 |
| GPR146 | -0.0902330 |
| STON1-GTF2A1L | -0.0902345 |
| MARCH11 | -0.0902403 |
| SHISA3 | -0.0902407 |
| PAPD4 | -0.0902471 |
| SLC25A38 | -0.0902713 |
| PLEKHH1 | -0.0902732 |
| MEPE | -0.0902854 |
| RNF41 | -0.0903073 |
| NKAIN4 | -0.0903214 |
| TRIM8 | -0.0903791 |
| ARHGEF28 | -0.0903888 |
| FGF7 | -0.0903911 |
| ADAMTS14 | -0.0904037 |
| SMUG1 | -0.0904119 |
| SLC44A1 | -0.0904356 |
| STRC | -0.0904667 |
| POFUT1 | -0.0905019 |
| SNRNP35 | -0.0905217 |
| QRICH2 | -0.0905628 |
| TTLL10 | -0.0905716 |
| ZNF420 | -0.0905771 |
| SALL1 | -0.0905783 |
| LEMD3 | -0.0905937 |
| TIGD4 | -0.0906078 |
| PPP2R2A | -0.0906265 |
| EFNB3 | -0.0906399 |
| C12orf54 | -0.0906409 |
| ZNF568 | -0.0906587 |
| RSPO1 | -0.0906626 |
| CLCN2 | -0.0906813 |
| SIX4 | -0.0906902 |
| KLF3 | -0.0907924 |
| CHDC2 | -0.0908589 |
| PURG | -0.0908622 |
| NSF | -0.0908772 |
| ZNF223 | -0.0908782 |
| TNFAIP8L1 | -0.0908796 |
| IFT57 | -0.0908878 |
| TRPA1 | -0.0909054 |
| KDM8 | -0.0909131 |
| HSPB2 | -0.0909286 |
| USP27X | -0.0909471 |
| SNRPN | -0.0909518 |
| SURF1 | -0.0909534 |
| MED13 | -0.0909934 |
| GDAP1L1 | -0.0909995 |
| ZNF225 | -0.0910222 |
| GSE1 | -0.0910414 |
| INTS1 | -0.0910782 |
| FAM20B | -0.0911224 |
| LRGUK | -0.0911262 |
| EPOR | -0.0911406 |
| FAM221B | -0.0911425 |
| FSCN2 | -0.0911462 |
| PHF21A | -0.0911491 |
| RARG | -0.0911498 |
| RUNX1T1 | -0.0911578 |
| ZNF358 | -0.0911668 |
| C4orf45 | -0.0911742 |
| GJA10 | -0.0911928 |
| PPIG | -0.0912110 |
| C19orf71 | -0.0912234 |
| SLC6A4 | -0.0912543 |
| PENK | -0.0912631 |
| SYTL1 | -0.0912781 |
| PTGER1 | -0.0912912 |
| GBE1 | -0.0912920 |
| KCNK18 | -0.0912965 |
| RNF123 | -0.0913167 |
| PCDH11Y | -0.0913432 |
| ZNF781 | -0.0913441 |
| CHD3 | -0.0913454 |
| KNOP1 | -0.0914201 |
| CFL2 | -0.0914224 |
| PKNOX1 | -0.0914295 |
| MANSC1 | -0.0914383 |
| KRT75 | -0.0914980 |
| TMEM116 | -0.0915172 |
| RPGRIP1L | -0.0915493 |
| ATXN2 | -0.0915538 |
| EXTL1 | -0.0915772 |
| CCDC114 | -0.0915837 |
| TBC1D3F | -0.0916019 |
| UPP2 | -0.0916239 |
| SRPX2 | -0.0916394 |
| ALPK3 | -0.0916633 |
| AMHR2 | -0.0916736 |
| FAM120A | -0.0917455 |
| DNAJC14 | -0.0917504 |
| CYP4F12 | -0.0917590 |
| ZFP62 | -0.0917630 |
| ZNF597 | -0.0917742 |
| SEC31B | -0.0917807 |
| RBM22 | -0.0918015 |
| OSBPL8 | -0.0918067 |
| DNAJB14 | -0.0918114 |
| GRIK4 | -0.0918118 |
| GALC | -0.0918133 |
| PCDHB12 | -0.0918200 |
| ZMYND8 | -0.0918497 |
| CRHBP | -0.0918504 |
| TAL2 | -0.0918635 |
| SACM1L | -0.0919127 |
| GPR137 | -0.0919132 |
| CRIPT | -0.0919346 |
| ZSCAN31 | -0.0919438 |
| CPT1C | -0.0919473 |
| NOP14 | -0.0919533 |
| ANGPTL5 | -0.0919680 |
| ADCYAP1 | -0.0920010 |
| OTOGL | -0.0920089 |
| UBTD2 | -0.0920390 |
| RAP1GDS1 | -0.0920400 |
| GOLGA1 | -0.0920461 |
| KRBOX4 | -0.0920533 |
| TCEB1 | -0.0920543 |
| ZFX | -0.0920791 |
| GABRB1 | -0.0920996 |
| ZCCHC17 | -0.0921013 |
| STRBP | -0.0921085 |
| PPP1R3D | -0.0921115 |
| FJX1 | -0.0921348 |
| DOCK6 | -0.0921420 |
| TMEM218 | -0.0921472 |
| PSEN2 | -0.0921675 |
| C6orf165 | -0.0922000 |
| HCFC2 | -0.0922201 |
| DNAJC21 | -0.0922371 |
| L1TD1 | -0.0922384 |
| PARD3B | -0.0922513 |
| SNCAIP | -0.0922775 |
| HES5 | -0.0922817 |
| NDN | -0.0922908 |
| CD9 | -0.0922964 |
| PDS5B | -0.0923027 |
| C8orf34 | -0.0923168 |
| DIDO1 | -0.0923462 |
| IK | -0.0923681 |
| LCN6 | -0.0923696 |
| KRBOX1 | -0.0924443 |
| B9D1 | -0.0924522 |
| BNC2 | -0.0924633 |
| ZNF791 | -0.0924884 |
| ZDHHC1 | -0.0924991 |
| KRIT1 | -0.0925106 |
| NFAT5 | -0.0925655 |
| MYH4 | -0.0925991 |
| BEND5 | -0.0926064 |
| PRKCZ | -0.0926114 |
| NLGN2 | -0.0926929 |
| SUGP2 | -0.0927118 |
| AZU1 | -0.0927209 |
| ZNF708 | -0.0928203 |
| DCLK3 | -0.0928227 |
| DHPS | -0.0928404 |
| ZNF678 | -0.0928459 |
| TMA16 | -0.0928608 |
| CHGB | -0.0928797 |
| KCNJ16 | -0.0929243 |
| MAP1LC3A | -0.0929290 |
| HNRNPA0 | -0.0929388 |
| SLC25A24 | -0.0929606 |
| COLEC11 | -0.0929676 |
| METAP1D | -0.0930032 |
| EFCAB6 | -0.0930257 |
| AAGAB | -0.0930314 |
| LPPR1 | -0.0931078 |
| ASIC3 | -0.0931107 |
| RFPL3 | -0.0931148 |
| AKAP11 | -0.0931234 |
| KCNIP1 | -0.0931373 |
| CCDC178 | -0.0931397 |
| NUP133 | -0.0931586 |
| EDEM3 | -0.0931592 |
| RCBTB1 | -0.0931679 |
| RHCE | -0.0931818 |
| ENGASE | -0.0931991 |
| ZNF627 | -0.0932018 |
| LURAP1 | -0.0932099 |
| MORF4L2 | -0.0932346 |
| AES | -0.0932372 |
| SUN1 | -0.0932455 |
| NAIP | -0.0932506 |
| PCMTD1 | -0.0932586 |
| ZNF302 | -0.0932652 |
| BTBD2 | -0.0932659 |
| SHANK3 | -0.0932663 |
| AGAP8 | -0.0932679 |
| ANXA11 | -0.0933016 |
| TSPAN7 | -0.0933102 |
| FASN | -0.0933135 |
| TMEM17 | -0.0933158 |
| OR4N4 | -0.0933239 |
| HOMEZ | -0.0933322 |
| PLEKHA4 | -0.0933568 |
| CAMSAP3 | -0.0933800 |
| SLC2A11 | -0.0934150 |
| RNF215 | -0.0934177 |
| DLC1 | -0.0934197 |
| HHIP | -0.0934212 |
| PYCR2 | -0.0934470 |
| RNASEH2C | -0.0934605 |
| BOD1L2 | -0.0935212 |
| RAX2 | -0.0935453 |
| KLC4 | -0.0935489 |
| PSD | -0.0935569 |
| TECPR2 | -0.0935572 |
| JAKMIP2 | -0.0935633 |
| ST6GALNAC6 | -0.0935711 |
| SERPINC1 | -0.0935735 |
| ATP6V1G1 | -0.0936661 |
| CCDC71 | -0.0936827 |
| PDZD7 | -0.0936849 |
| EFR3B | -0.0936888 |
| TEF | -0.0937089 |
| FLT3 | -0.0937231 |
| SLC9C1 | -0.0937245 |
| C6orf48 | -0.0937449 |
| TMED4 | -0.0937653 |
| EFCAB4B | -0.0937834 |
| ZNF16 | -0.0938290 |
| NKAIN3 | -0.0938316 |
| KCNAB1 | -0.0938452 |
| KDM3B | -0.0938958 |
| AKIP1 | -0.0939244 |
| DIRAS2 | -0.0939326 |
| FLG | -0.0939401 |
| GAS2L2 | -0.0939410 |
| CIAO1 | -0.0939479 |
| ANKS1B | -0.0939578 |
| TMEM59L | -0.0939684 |
| OPCML | -0.0939770 |
| C4orf36 | -0.0939821 |
| ZNF667 | -0.0939882 |
| VWC2 | -0.0940112 |
| SST | -0.0940335 |
| MAZ | -0.0940343 |
| CCDC149 | -0.0940698 |
| PPP2CA | -0.0940722 |
| SIDT1 | -0.0940965 |
| ADAM23 | -0.0940973 |
| GTF3C1 | -0.0941024 |
| SCOC | -0.0941154 |
| SCN8A | -0.0941165 |
| FARP2 | -0.0941515 |
| PCNXL2 | -0.0941763 |
| TRAM1L1 | -0.0942701 |
| GCLM | -0.0943531 |
| YPEL2 | -0.0943904 |
| KLHL15 | -0.0944220 |
| PTEN | -0.0944303 |
| KCTD4 | -0.0944331 |
| SLC7A10 | -0.0944379 |
| MUC1 | -0.0944676 |
| BAI3 | -0.0944831 |
| PEX1 | -0.0945038 |
| MBD3L2 | -0.0945039 |
| WDR72 | -0.0945138 |
| SHOX2 | -0.0945240 |
| AKR1D1 | -0.0945487 |
| POTEE | -0.0945538 |
| MARC1 | -0.0945643 |
| RNF25 | -0.0946283 |
| RTN4 | -0.0946489 |
| ANGPTL1 | -0.0946596 |
| TRIM17 | -0.0947134 |
| TNNC1 | -0.0947319 |
| HAO2 | -0.0947412 |
| SPDYE2 | -0.0947465 |
| NEO1 | -0.0947717 |
| PCDHAC2 | -0.0947759 |
| CPS1 | -0.0947962 |
| SCNN1D | -0.0948146 |
| ZBTB18 | -0.0948193 |
| FAM46B | -0.0948386 |
| COX6A1 | -0.0948760 |
| EGF | -0.0948786 |
| PCDH7 | -0.0949025 |
| B3GALT6 | -0.0949236 |
| HIST2H2AB | -0.0949636 |
| SEPT5 | -0.0950370 |
| EEF2 | -0.0950843 |
| NPIPB3 | -0.0950945 |
| AFAP1L2 | -0.0951054 |
| CPO | -0.0951489 |
| POMZP3 | -0.0951639 |
| MAN2C1 | -0.0951678 |
| SLC12A5 | -0.0951870 |
| ING4 | -0.0951874 |
| SFXN5 | -0.0952270 |
| CSMD1 | -0.0952348 |
| RSPH4A | -0.0952370 |
| TCTEX1D1 | -0.0952635 |
| UQCR11 | -0.0952745 |
| COG6 | -0.0952986 |
| EID2B | -0.0953018 |
| ADCK4 | -0.0953482 |
| KIAA1958 | -0.0953583 |
| DYDC2 | -0.0953631 |
| TBCK | -0.0954332 |
| SLC30A5 | -0.0954409 |
| ZNF605 | -0.0954573 |
| RPS27L | -0.0954659 |
| EFCAB14 | -0.0954973 |
| PTPRR | -0.0955087 |
| AVPR2 | -0.0955430 |
| FBLN7 | -0.0956100 |
| CST11 | -0.0956112 |
| FZR1 | -0.0956128 |
| SNED1 | -0.0957029 |
| MS4A14 | -0.0958171 |
| CCDC122 | -0.0958284 |
| CPT1A | -0.0958674 |
| SULT1B1 | -0.0958726 |
| MFAP4 | -0.0959070 |
| AQP7 | -0.0959125 |
| VPS13D | -0.0959387 |
| NDRG4 | -0.0959406 |
| GNS | -0.0959681 |
| PGBD4 | -0.0959828 |
| POPDC2 | -0.0960032 |
| ARG1 | -0.0960195 |
| TMEM5 | -0.0960333 |
| ZNF880 | -0.0960529 |
| TTC9 | -0.0960704 |
| FXYD1 | -0.0960741 |
| FAM114A1 | -0.0960818 |
| MYF5 | -0.0961036 |
| COQ5 | -0.0961381 |
| KIAA0196 | -0.0961540 |
| HKR1 | -0.0961598 |
| WWC2 | -0.0961668 |
| DRD1 | -0.0961702 |
| MAGEB18 | -0.0961762 |
| TRMT44 | -0.0961862 |
| PPME1 | -0.0962700 |
| PQLC3 | -0.0962721 |
| ATF7IP2 | -0.0963326 |
| ARHGAP5 | -0.0963665 |
| RNASEL | -0.0963685 |
| NDUFAF6 | -0.0963881 |
| HCN1 | -0.0964027 |
| TMEM135 | -0.0965052 |
| TPD52 | -0.0965283 |
| PHAX | -0.0965358 |
| ANKRD46 | -0.0965378 |
| KIAA1598 | -0.0965476 |
| MC1R | -0.0965518 |
| KLHL23 | -0.0965660 |
| PDHX | -0.0965736 |
| B4GALT6 | -0.0966518 |
| MON2 | -0.0966530 |
| ZNF527 | -0.0967091 |
| FST | -0.0967102 |
| CDRT15 | -0.0967253 |
| RDH5 | -0.0967607 |
| BCL9 | -0.0967782 |
| C1QTNF6 | -0.0967978 |
| CHIC1 | -0.0968327 |
| NSMF | -0.0968378 |
| ZNF180 | -0.0969119 |
| ARL17A | -0.0969279 |
| GLB1L | -0.0969355 |
| DLX2 | -0.0969425 |
| EFHB | -0.0969564 |
| ZNF345 | -0.0969794 |
| EFTUD1 | -0.0969996 |
| IFT52 | -0.0970002 |
| NHLRC3 | -0.0970240 |
| ANO4 | -0.0970299 |
| ZNF85 | -0.0970347 |
| SUB1 | -0.0970796 |
| NLGN4X | -0.0971162 |
| CHP1 | -0.0971760 |
| SPACA4 | -0.0971958 |
| PPBP | -0.0972176 |
| OTOA | -0.0972338 |
| VSIG2 | -0.0972476 |
| MAGEE1 | -0.0972545 |
| MOK | -0.0972593 |
| IL25 | -0.0972615 |
| PLGLB1 | -0.0972758 |
| CA4 | -0.0973070 |
| SLC39A4 | -0.0973190 |
| ACTR10 | -0.0973346 |
| RNF139 | -0.0973564 |
| TSGA10 | -0.0973682 |
| MAN2B2 | -0.0974216 |
| ZFPM2 | -0.0974317 |
| PLA2R1 | -0.0974663 |
| PRDX2 | -0.0974689 |
| COL21A1 | -0.0974713 |
| GABARAPL2 | -0.0975333 |
| DNAJA3 | -0.0975823 |
| CMTM2 | -0.0975996 |
| TMPRSS9 | -0.0976236 |
| KANSL3 | -0.0976657 |
| ABCA6 | -0.0976840 |
| HIST1H4J | -0.0977149 |
| SPG20 | -0.0977237 |
| NECAB1 | -0.0977256 |
| HIST2H2BE | -0.0977376 |
| TNPO1 | -0.0977452 |
| ZP3 | -0.0977520 |
| KCTD1 | -0.0977537 |
| ADAD2 | -0.0977603 |
| SS18L1 | -0.0977736 |
| MED16 | -0.0978059 |
| ELMOD3 | -0.0978069 |
| PHF13 | -0.0978113 |
| LRRFIP1 | -0.0978349 |
| TNFAIP8L3 | -0.0978654 |
| GNAI1 | -0.0978764 |
| C1QL1 | -0.0978932 |
| SEMA4G | -0.0979051 |
| EFHD1 | -0.0979288 |
| ANKRD31 | -0.0979356 |
| FEM1A | -0.0979420 |
| YTHDC1 | -0.0979582 |
| C15orf57 | -0.0980129 |
| RFPL1 | -0.0980312 |
| ZNF479 | -0.0980327 |
| CCDC36 | -0.0980427 |
| CAPN12 | -0.0980468 |
| PBX2 | -0.0980866 |
| MRVI1 | -0.0981152 |
| CLEC14A | -0.0981311 |
| BICC1 | -0.0981533 |
| ATP13A2 | -0.0981590 |
| TTC29 | -0.0981623 |
| SHROOM4 | -0.0981874 |
| LMAN2L | -0.0981994 |
| TOMM34 | -0.0982079 |
| ZNF69 | -0.0982186 |
| CCDC117 | -0.0982216 |
| FOXD4 | -0.0982468 |
| PMS2 | -0.0982511 |
| ZIM2 | -0.0982675 |
| IL1RL1 | -0.0982913 |
| CBX4 | -0.0982965 |
| BBS9 | -0.0983064 |
| C22orf23 | -0.0983124 |
| ARMC3 | -0.0983155 |
| ZNF418 | -0.0983295 |
| NDUFC1 | -0.0983487 |
| MXRA7 | -0.0983698 |
| PRIMPOL | -0.0983792 |
| EIF3F | -0.0984004 |
| CDK15 | -0.0984255 |
| ZNF784 | -0.0984384 |
| MTR | -0.0984402 |
| CNGA3 | -0.0984699 |
| NTN5 | -0.0984850 |
| GKN2 | -0.0984860 |
| EXOC8 | -0.0985040 |
| NEDD4 | -0.0985302 |
| LRSAM1 | -0.0985527 |
| ROMO1 | -0.0985599 |
| CA5B | -0.0985860 |
| EFHC2 | -0.0985938 |
| CELF3 | -0.0986184 |
| ASTN1 | -0.0986292 |
| RB1 | -0.0986306 |
| AASS | -0.0986622 |
| SCUBE1 | -0.0987356 |
| DPPA3 | -0.0987396 |
| ELOVL6 | -0.0987430 |
| CD109 | -0.0987467 |
| CPSF1 | -0.0987930 |
| CXorf27 | -0.0988478 |
| EGFL7 | -0.0988579 |
| C3orf70 | -0.0989186 |
| MACROD2 | -0.0989570 |
| TRIM44 | -0.0989712 |
| TTI2 | -0.0990055 |
| TRIM9 | -0.0990109 |
| WDR73 | -0.0990154 |
| ZNF28 | -0.0990161 |
| RND1 | -0.0990199 |
| LEFTY1 | -0.0990263 |
| HSPA9 | -0.0990324 |
| PDZD8 | -0.0990576 |
| FKTN | -0.0990806 |
| BHMT2 | -0.0990904 |
| KIAA1462 | -0.0991343 |
| CYTL1 | -0.0991437 |
| C1QTNF9 | -0.0991882 |
| ZBTB46 | -0.0992025 |
| ZNF106 | -0.0992028 |
| ZNF557 | -0.0992249 |
| CACNA2D4 | -0.0992609 |
| PMP2 | -0.0993084 |
| ZNF729 | -0.0993244 |
| CDIPT | -0.0993368 |
| ARL6IP4 | -0.0993420 |
| SERINC1 | -0.0993677 |
| UBE2QL1 | -0.0994192 |
| FZD3 | -0.0994209 |
| ATP5F1 | -0.0994261 |
| ARL14EP | -0.0994320 |
| WDR16 | -0.0994358 |
| DSG1 | -0.0994411 |
| ZNF614 | -0.0994482 |
| RIMS2 | -0.0994746 |
| HS3ST4 | -0.0994889 |
| CUEDC1 | -0.0994933 |
| PITX2 | -0.0995106 |
| MYBL1 | -0.0995182 |
| CAPZA3 | -0.0995304 |
| ZNF324 | -0.0995498 |
| TTC21B | -0.0995895 |
| PCDHGA3 | -0.0995959 |
| UBE4B | -0.0996071 |
| SLC23A2 | -0.0996194 |
| BAZ2A | -0.0996392 |
| CSDC2 | -0.0996428 |
| ZNF738 | -0.0996516 |
| COQ10A | -0.0996524 |
| NGFRAP1 | -0.0996554 |
| DOK4 | -0.0996570 |
| GRIA1 | -0.0996671 |
| NAALAD2 | -0.0996719 |
| NMRAL1 | -0.0996733 |
| FBXO16 | -0.0996781 |
| EPG5 | -0.0996807 |
| SPPL3 | -0.0996839 |
| NPHP3 | -0.0996880 |
| THAP2 | -0.0996912 |
| VIL1 | -0.0997090 |
| CDC42BPA | -0.0997245 |
| AMMECR1L | -0.0997298 |
| UROD | -0.0997890 |
| HINT2 | -0.0998713 |
| KIAA0895 | -0.0998752 |
| DCP1A | -0.0998808 |
| LEPR | -0.0998830 |
| RABEP2 | -0.0999056 |
| CCDC22 | -0.0999214 |
| PHF7 | -0.0999231 |
| ATN1 | -0.0999251 |
| PLCE1 | -0.0999362 |
| RMDN2 | -0.0999382 |
| DCP1B | -0.0999424 |
| REL | -0.0999443 |
| TAL1 | -0.0999818 |
| DGKD | -0.0999860 |
| GNA14 | -0.0999883 |
| ESPN | -0.0999908 |
| TOP1MT | -0.1000102 |
| TNK1 | -0.1000347 |
| MYO15A | -0.1000401 |
| SLC36A2 | -0.1000492 |
| FTO | -0.1000984 |
| SVEP1 | -0.1000985 |
| NTF3 | -0.1001310 |
| NPC1L1 | -0.1001615 |
| KL | -0.1001806 |
| TSPAN9 | -0.1001843 |
| GOLPH3L | -0.1001894 |
| RFNG | -0.1002129 |
| LRRC37A3 | -0.1002347 |
| MTHFD2L | -0.1002609 |
| DUOX1 | -0.1002732 |
| CNBD2 | -0.1002826 |
| TECR | -0.1002969 |
| ANAPC4 | -0.1003095 |
| MYO16 | -0.1003147 |
| DNER | -0.1003435 |
| TMEM66 | -0.1003436 |
| SLC27A4 | -0.1003538 |
| PER1 | -0.1003939 |
| ZNF322 | -0.1004232 |
| B9D2 | -0.1004285 |
| SNX25 | -0.1004328 |
| KBTBD4 | -0.1004374 |
| HIBADH | -0.1004671 |
| LGR4 | -0.1004846 |
| DTWD1 | -0.1004896 |
| C10orf95 | -0.1005325 |
| SUCLA2 | -0.1005339 |
| DUSP16 | -0.1005580 |
| BCL6B | -0.1005694 |
| FNBP1L | -0.1005761 |
| GABRB3 | -0.1005925 |
| ATPIF1 | -0.1006214 |
| WDR65 | -0.1006232 |
| ZMYM4 | -0.1006371 |
| UQCRC2 | -0.1006457 |
| LSMEM2 | -0.1006494 |
| SLCO1B1 | -0.1006538 |
| MED7 | -0.1006770 |
| TEX19 | -0.1007176 |
| SORBS1 | -0.1007235 |
| OSBPL1A | -0.1007540 |
| CYB561D2 | -0.1007798 |
| ZNF613 | -0.1008117 |
| TSHZ3 | -0.1008477 |
| AGPS | -0.1008735 |
| ALDOA | -0.1009268 |
| MKNK2 | -0.1009387 |
| CDH6 | -0.1009441 |
| EYA1 | -0.1009851 |
| GNAO1 | -0.1010019 |
| MYL6B | -0.1010143 |
| RABL3 | -0.1010168 |
| PISD | -0.1010307 |
| EXTL2 | -0.1010355 |
| KTN1 | -0.1010603 |
| KCNK2 | -0.1010719 |
| ZNF419 | -0.1010779 |
| CA3 | -0.1011129 |
| BCO2 | -0.1011196 |
| NUDT18 | -0.1011269 |
| OPN1LW | -0.1011700 |
| DYNC1I2 | -0.1011881 |
| EXD3 | -0.1011946 |
| ANKRD13C | -0.1012057 |
| TUT1 | -0.1012209 |
| SERTAD3 | -0.1012308 |
| ALS2CR12 | -0.1012361 |
| COPS4 | -0.1012877 |
| TRIM52 | -0.1013240 |
| AHCTF1 | -0.1013343 |
| SHE | -0.1013548 |
| CSRNP2 | -0.1013739 |
| FAM162A | -0.1014383 |
| TRIM23 | -0.1014443 |
| BTBD9 | -0.1014458 |
| PCDH1 | -0.1014542 |
| METTL25 | -0.1014691 |
| GOLGA6L9 | -0.1015767 |
| SCP2 | -0.1016333 |
| PLEKHG4 | -0.1016477 |
| ALDH1L1 | -0.1016957 |
| EXOC7 | -0.1017472 |
| HPD | -0.1017498 |
| C1QTNF9B | -0.1017543 |
| SLC9A8 | -0.1017986 |
| IPP | -0.1018369 |
| PIAS3 | -0.1018616 |
| SEC62 | -0.1018914 |
| PCBP2 | -0.1019114 |
| ANKRD23 | -0.1019325 |
| C10orf35 | -0.1019454 |
| EAF1 | -0.1019684 |
| SLITRK5 | -0.1019706 |
| UNKL | -0.1019998 |
| ZNF554 | -0.1020346 |
| RMDN3 | -0.1020445 |
| DPP8 | -0.1020460 |
| STMN4 | -0.1020786 |
| HMGN5 | -0.1021031 |
| OSBPL5 | -0.1021085 |
| SPSB2 | -0.1021421 |
| FGF20 | -0.1021537 |
| MARCH4 | -0.1021560 |
| JAG2 | -0.1021564 |
| ZNF671 | -0.1021597 |
| OR51E2 | -0.1021629 |
| DHFRL1 | -0.1022329 |
| KIAA1429 | -0.1022464 |
| C9orf64 | -0.1022563 |
| LARP6 | -0.1022665 |
| COX14 | -0.1022714 |
| ANAPC16 | -0.1023049 |
| ITPK1 | -0.1023186 |
| ZNF287 | -0.1023244 |
| CGRRF1 | -0.1023297 |
| DMTF1 | -0.1023479 |
| HMGCLL1 | -0.1023550 |
| FBXO3 | -0.1023850 |
| HSPG2 | -0.1024250 |
| UEVLD | -0.1024281 |
| C4orf48 | -0.1024298 |
| COL3A1 | -0.1024332 |
| THRSP | -0.1024408 |
| HSF1 | -0.1024739 |
| MT1M | -0.1024850 |
| BBIP1 | -0.1024977 |
| COL4A3BP | -0.1024978 |
| PCDH12 | -0.1025114 |
| TAF15 | -0.1025166 |
| C7orf50 | -0.1025258 |
| SYNGAP1 | -0.1025274 |
| OTUD3 | -0.1026443 |
| C21orf2 | -0.1026867 |
| SLC4A10 | -0.1027193 |
| THAP9 | -0.1027516 |
| DSTYK | -0.1027593 |
| ZNF182 | -0.1027838 |
| ZBTB45 | -0.1028080 |
| SRSF6 | -0.1028427 |
| SPIN2B | -0.1028515 |
| UBN2 | -0.1028575 |
| RFX6 | -0.1028673 |
| C17orf74 | -0.1028851 |
| ADAMTS6 | -0.1028857 |
| SLC4A4 | -0.1028868 |
| SGSM2 | -0.1028980 |
| SLC39A10 | -0.1029351 |
| MTMR10 | -0.1029367 |
| ALG13 | -0.1029569 |
| RPS14 | -0.1029596 |
| FAM198A | -0.1030296 |
| SYP | -0.1030312 |
| GPC3 | -0.1030341 |
| GRM4 | -0.1030349 |
| FAM200A | -0.1030810 |
| TESK2 | -0.1030967 |
| TSPYL1 | -0.1031010 |
| PIWIL2 | -0.1031141 |
| SMIM3 | -0.1031244 |
| FAM71E1 | -0.1031297 |
| UBXN11 | -0.1031608 |
| CORIN | -0.1031793 |
| SBF2 | -0.1032451 |
| EPDR1 | -0.1032572 |
| ZNF696 | -0.1032581 |
| PLXNA3 | -0.1032607 |
| MGAM | -0.1032821 |
| ASB8 | -0.1033031 |
| PRAF2 | -0.1033265 |
| AMER3 | -0.1033625 |
| SLC5A10 | -0.1033764 |
| SIRT1 | -0.1033817 |
| PHF2 | -0.1034402 |
| MRPL24 | -0.1034641 |
| PGGT1B | -0.1034778 |
| RGS12 | -0.1034796 |
| ADRBK2 | -0.1034923 |
| PDLIM4 | -0.1035260 |
| UBOX5 | -0.1035428 |
| WDR27 | -0.1035459 |
| CADM2 | -0.1035620 |
| SMCO3 | -0.1035822 |
| KLHL28 | -0.1035868 |
| NRXN2 | -0.1036175 |
| TMED8 | -0.1036462 |
| SRFBP1 | -0.1036844 |
| MFSD10 | -0.1036888 |
| RTDR1 | -0.1037260 |
| DCXR | -0.1037369 |
| PTH1R | -0.1038303 |
| EML1 | -0.1038400 |
| DAGLA | -0.1038681 |
| C15orf38-AP3S2 | -0.1038696 |
| ZNF768 | -0.1038717 |
| ADH1A | -0.1038907 |
| SENP7 | -0.1038939 |
| CCDC68 | -0.1039073 |
| CNKSR1 | -0.1039111 |
| ZNF623 | -0.1039167 |
| NEK4 | -0.1039783 |
| ODF3L1 | -0.1040038 |
| CBX8 | -0.1040974 |
| COL1A1 | -0.1041604 |
| CILP | -0.1041793 |
| MTNR1B | -0.1042376 |
| B3GNT1 | -0.1043008 |
| FAM168A | -0.1043913 |
| CCPG1 | -0.1044095 |
| CALCR | -0.1044542 |
| DENND6A | -0.1044576 |
| KRT32 | -0.1045011 |
| IRX1 | -0.1045321 |
| HES4 | -0.1045580 |
| MINOS1 | -0.1045807 |
| MCHR1 | -0.1045936 |
| CLEC16A | -0.1045985 |
| RANBP3L | -0.1046359 |
| LOH12CR2 | -0.1046534 |
| PHKG2 | -0.1046622 |
| PNRC2 | -0.1046638 |
| RSF1 | -0.1046654 |
| PCK1 | -0.1046862 |
| PGPEP1 | -0.1047705 |
| RGS13 | -0.1047784 |
| ASIC2 | -0.1047985 |
| OMA1 | -0.1048031 |
| TMEM222 | -0.1048079 |
| DNAH9 | -0.1048101 |
| FAM160B2 | -0.1048206 |
| PIGN | -0.1048233 |
| BHLHB9 | -0.1048457 |
| RMDN1 | -0.1048735 |
| CYB5B | -0.1048845 |
| RNF151 | -0.1048879 |
| SNTN | -0.1048888 |
| LOXL1 | -0.1049059 |
| TMEM178A | -0.1049185 |
| GSTCD | -0.1049215 |
| ZNF354B | -0.1049399 |
| FEZ1 | -0.1049580 |
| ZNF197 | -0.1050003 |
| BLZF1 | -0.1050094 |
| MTHFR | -0.1050345 |
| ZNF17 | -0.1050687 |
| CBLN1 | -0.1050709 |
| ICA1L | -0.1050833 |
| DNAJC18 | -0.1051005 |
| HBA1 | -0.1051107 |
| SEMG1 | -0.1051429 |
| ZNF484 | -0.1051638 |
| MMRN1 | -0.1051733 |
| RHBG | -0.1051843 |
| TMEM134 | -0.1052704 |
| NDFIP1 | -0.1052748 |
| CYP2U1 | -0.1053701 |
| RGL2 | -0.1053776 |
| ZNF385D | -0.1053865 |
| WFDC1 | -0.1054102 |
| BCHE | -0.1054278 |
| ETFB | -0.1054299 |
| TMEM249 | -0.1054617 |
| SLC18A2 | -0.1054628 |
| PIK3R5 | -0.1054777 |
| ATP9B | -0.1054925 |
| GZF1 | -0.1055712 |
| TPGS1 | -0.1056021 |
| C1orf101 | -0.1056062 |
| FSTL4 | -0.1056066 |
| CHD9 | -0.1056541 |
| GTF2IRD1 | -0.1056588 |
| DMKN | -0.1056849 |
| RFTN2 | -0.1056963 |
| PPP6R3 | -0.1057460 |
| CALCOCO1 | -0.1057556 |
| COL7A1 | -0.1057662 |
| FAM173B | -0.1057860 |
| HGF | -0.1058514 |
| RPL9 | -0.1058624 |
| NFE2 | -0.1058885 |
| CA10 | -0.1059096 |
| AIFM3 | -0.1059107 |
| NTM | -0.1059313 |
| EZH1 | -0.1059504 |
| KLHL21 | -0.1059741 |
| NEMF | -0.1059924 |
| KCTD18 | -0.1060303 |
| NBPF3 | -0.1060383 |
| SPESP1 | -0.1060438 |
| ZBTB4 | -0.1060624 |
| CDK7 | -0.1061066 |
| STXBP4 | -0.1061183 |
| AQR | -0.1061306 |
| NFATC2IP | -0.1061489 |
| OBFC1 | -0.1061517 |
| MRPS28 | -0.1061565 |
| ARHGAP29 | -0.1061845 |
| SBSPON | -0.1061869 |
| KDSR | -0.1062028 |
| PARP3 | -0.1062104 |
| FRA10AC1 | -0.1062278 |
| ZNF556 | -0.1062448 |
| TWISTNB | -0.1063047 |
| TMEM42 | -0.1063373 |
| MRI1 | -0.1063693 |
| CXCR2 | -0.1063873 |
| CCDC130 | -0.1063879 |
| KIAA1191 | -0.1063921 |
| FOXP1 | -0.1064135 |
| CAPN5 | -0.1064160 |
| AUH | -0.1064445 |
| SGCB | -0.1064607 |
| PTER | -0.1064703 |
| FBXO4 | -0.1065352 |
| NABP2 | -0.1065404 |
| TBC1D14 | -0.1065633 |
| ASAP3 | -0.1065733 |
| GNAQ | -0.1065743 |
| TMEM232 | -0.1066514 |
| PCDHGA8 | -0.1066843 |
| FRMD6 | -0.1067082 |
| CTDSP2 | -0.1067525 |
| USP53 | -0.1067561 |
| MORN2 | -0.1067759 |
| CHST14 | -0.1067838 |
| EIF2AK4 | -0.1068033 |
| SLITRK1 | -0.1068090 |
| RPF1 | -0.1068176 |
| VILL | -0.1068213 |
| FAM43B | -0.1069120 |
| CDK5RAP3 | -0.1069308 |
| ZNF483 | -0.1069356 |
| TSSC4 | -0.1069388 |
| GPR182 | -0.1069488 |
| DZIP3 | -0.1069624 |
| MCF2L | -0.1069807 |
| TNKS | -0.1070336 |
| KSR2 | -0.1070478 |
| SCAMP4 | -0.1070557 |
| BTBD1 | -0.1070724 |
| NPIPB6 | -0.1070741 |
| TATDN3 | -0.1070917 |
| MAP4K5 | -0.1071417 |
| SLC14A1 | -0.1071555 |
| ZNF414 | -0.1072447 |
| SYT9 | -0.1072449 |
| PTPRG | -0.1072715 |
| IBTK | -0.1072997 |
| RILPL1 | -0.1073008 |
| GLIS2 | -0.1073167 |
| FER | -0.1073255 |
| PLLP | -0.1073322 |
| ALG1 | -0.1073419 |
| PTPMT1 | -0.1073446 |
| ANAPC13 | -0.1073497 |
| C1orf213 | -0.1073558 |
| IFT46 | -0.1073655 |
| MTX3 | -0.1073667 |
| PAFAH2 | -0.1073874 |
| GLRB | -0.1074411 |
| C1orf95 | -0.1074702 |
| COQ6 | -0.1075002 |
| RAP1GAP | -0.1075384 |
| GAP43 | -0.1075748 |
| ST8SIA5 | -0.1076091 |
| FREM1 | -0.1076281 |
| SOCS4 | -0.1076334 |
| CLDN11 | -0.1076428 |
| PDIK1L | -0.1076590 |
| THEM6 | -0.1076698 |
| RAB39B | -0.1076761 |
| HIVEP3 | -0.1076785 |
| FCRLB | -0.1076857 |
| PXMP4 | -0.1077110 |
| SHROOM2 | -0.1077206 |
| ARMC5 | -0.1077278 |
| UBXN2B | -0.1077415 |
| THAP6 | -0.1077530 |
| ZCCHC3 | -0.1077777 |
| TMEM88 | -0.1077910 |
| SLC27A3 | -0.1077978 |
| FBXL15 | -0.1077985 |
| TTC3 | -0.1078035 |
| GPR137C | -0.1078185 |
| NCAM1 | -0.1078350 |
| RAB28 | -0.1078518 |
| CRYL1 | -0.1078548 |
| SOS2 | -0.1079582 |
| HERC2 | -0.1079904 |
| ZNF625 | -0.1080298 |
| CAND1 | -0.1080496 |
| FAM122B | -0.1080612 |
| FECH | -0.1081115 |
| SLC45A1 | -0.1081268 |
| ZNF800 | -0.1081302 |
| RALYL | -0.1081492 |
| SLC47A2 | -0.1081656 |
| CPNE3 | -0.1081846 |
| LNX1 | -0.1081974 |
| CEP44 | -0.1082018 |
| GMPR2 | -0.1082180 |
| CREBL2 | -0.1082474 |
| DNAJC19 | -0.1082689 |
| KCNE2 | -0.1083406 |
| ZNF141 | -0.1083514 |
| BBS5 | -0.1083770 |
| CEP19 | -0.1084704 |
| KRT31 | -0.1084824 |
| EDDM3B | -0.1084894 |
| NR3C2 | -0.1085152 |
| MAMDC4 | -0.1085320 |
| RYR2 | -0.1085430 |
| UCN3 | -0.1085854 |
| GEMIN8 | -0.1085878 |
| RBMS3 | -0.1086049 |
| SKIDA1 | -0.1086783 |
| DMGDH | -0.1087309 |
| UGT2B4 | -0.1087537 |
| DLL1 | -0.1088173 |
| BDH2 | -0.1088231 |
| PTPRH | -0.1088246 |
| RBM3 | -0.1089157 |
| SSC5D | -0.1089246 |
| CCS | -0.1089405 |
| MAT2A | -0.1089521 |
| CHMP4B | -0.1089541 |
| GNB5 | -0.1089906 |
| DBX2 | -0.1090096 |
| URGCP | -0.1090237 |
| PTGDR2 | -0.1090579 |
| SCML1 | -0.1090628 |
| HUS1B | -0.1091360 |
| HOXA13 | -0.1091746 |
| APC | -0.1091758 |
| ZNF564 | -0.1091861 |
| GFM2 | -0.1092043 |
| ARPP21 | -0.1092547 |
| CDH18 | -0.1092554 |
| ATP5D | -0.1092972 |
| XYLT2 | -0.1093386 |
| C14orf28 | -0.1093423 |
| DYNLRB1 | -0.1093619 |
| PIK3R2 | -0.1093675 |
| MARCH6 | -0.1093819 |
| NSL1 | -0.1094201 |
| RBM43 | -0.1094270 |
| PLEKHA3 | -0.1094383 |
| PIFO | -0.1094854 |
| TRMT10B | -0.1094910 |
| MBOAT7 | -0.1095154 |
| MAOB | -0.1095308 |
| C4orf22 | -0.1095510 |
| SPATA2 | -0.1095762 |
| ZNF263 | -0.1096120 |
| PLD6 | -0.1096749 |
| CMTM8 | -0.1096802 |
| KIFAP3 | -0.1096950 |
| SLC9A3R2 | -0.1096977 |
| SGK2 | -0.1097219 |
| ZNF395 | -0.1097334 |
| COPS2 | -0.1097510 |
| SLC30A1 | -0.1097558 |
| CYP4Z1 | -0.1098190 |
| GDF1 | -0.1098207 |
| PDGFC | -0.1098251 |
| STAU2 | -0.1098396 |
| WDR5B | -0.1099098 |
| SPHK2 | -0.1099284 |
| NID1 | -0.1099986 |
| CTDSPL2 | -0.1100003 |
| ASH1L | -0.1100415 |
| ZBTB20 | -0.1101180 |
| MLH3 | -0.1101442 |
| NGFR | -0.1101544 |
| WDR31 | -0.1101592 |
| TMEM35 | -0.1101862 |
| CYC1 | -0.1101889 |
| RWDD3 | -0.1102080 |
| EXOSC4 | -0.1102116 |
| TSR3 | -0.1102133 |
| ZNF160 | -0.1102156 |
| NINJ1 | -0.1102399 |
| CCDC113 | -0.1102691 |
| APEH | -0.1102702 |
| SCAF11 | -0.1103230 |
| TBC1D30 | -0.1103286 |
| SUDS3 | -0.1103396 |
| FYCO1 | -0.1103488 |
| PDE1A | -0.1103585 |
| MORN5 | -0.1103727 |
| POGZ | -0.1103981 |
| IQCC | -0.1105181 |
| SAMD14 | -0.1105463 |
| TMEM170B | -0.1105810 |
| ENO3 | -0.1106375 |
| NIPAL3 | -0.1106624 |
| RHOBTB1 | -0.1106974 |
| APLN | -0.1107307 |
| FAM203A | -0.1107955 |
| SLC48A1 | -0.1108102 |
| C5orf54 | -0.1108153 |
| GNG3 | -0.1108458 |
| DIO3 | -0.1108576 |
| CBLC | -0.1108648 |
| NHS | -0.1108809 |
| CALML6 | -0.1108968 |
| SNAI2 | -0.1109139 |
| DKK3 | -0.1109574 |
| C2orf76 | -0.1109866 |
| CCNDBP1 | -0.1109984 |
| FRYL | -0.1110273 |
| OGFOD2 | -0.1110408 |
| KERA | -0.1110424 |
| SLC7A13 | -0.1110759 |
| FABP3 | -0.1110918 |
| DEPTOR | -0.1111053 |
| PDE8A | -0.1111296 |
| AFP | -0.1111310 |
| GNPTG | -0.1111546 |
| NDUFA4 | -0.1111623 |
| SLC25A23 | -0.1112493 |
| TTC39C | -0.1113210 |
| VSIG10 | -0.1113288 |
| UQCRB | -0.1113387 |
| PNCK | -0.1114012 |
| SLC8A2 | -0.1114268 |
| IP6K3 | -0.1114495 |
| WDR52 | -0.1114512 |
| SOD1 | -0.1114702 |
| NDUFA5 | -0.1114806 |
| CTDSP1 | -0.1115065 |
| CSNK1G1 | -0.1115132 |
| ARID1A | -0.1115500 |
| TTC12 | -0.1116269 |
| CDC42BPB | -0.1116291 |
| TYW3 | -0.1116408 |
| SCARB1 | -0.1116541 |
| COX17 | -0.1116914 |
| NMNAT1 | -0.1117102 |
| GRB14 | -0.1117127 |
| MTUS1 | -0.1117143 |
| CLASP2 | -0.1117169 |
| HP1BP3 | -0.1117171 |
| NUBP2 | -0.1117251 |
| MROH8 | -0.1117709 |
| LCOR | -0.1118280 |
| ZBED3 | -0.1118388 |
| ARFIP2 | -0.1118504 |
| EBLN2 | -0.1118527 |
| RAI1 | -0.1118536 |
| HPX | -0.1118597 |
| PSD2 | -0.1119164 |
| SLC25A48 | -0.1119479 |
| NCKAP1 | -0.1119698 |
| C10orf88 | -0.1119905 |
| MYCT1 | -0.1120081 |
| RAB3IP | -0.1120345 |
| SIK3 | -0.1120352 |
| QSOX1 | -0.1120657 |
| ADAM20 | -0.1120954 |
| SLC39A13 | -0.1121280 |
| PCDHGB4 | -0.1121432 |
| SLFNL1 | -0.1121491 |
| PPP1R42 | -0.1121881 |
| TMEFF2 | -0.1122187 |
| GIGYF2 | -0.1122256 |
| ALG1L | -0.1122510 |
| NSUN7 | -0.1122944 |
| FTCD | -0.1123450 |
| RFPL2 | -0.1123637 |
| PROCR | -0.1123810 |
| RNF208 | -0.1124364 |
| NKAIN2 | -0.1124596 |
| CCNG1 | -0.1125085 |
| ZNF233 | -0.1125490 |
| ZNF497 | -0.1125658 |
| ZDHHC4 | -0.1125744 |
| C5orf38 | -0.1125859 |
| ZC3H7A | -0.1126181 |
| ZNF48 | -0.1126781 |
| NENF | -0.1126781 |
| STX18 | -0.1127618 |
| RIOK2 | -0.1127934 |
| TMEM192 | -0.1127937 |
| TUSC5 | -0.1129439 |
| NOTCH4 | -0.1129728 |
| DAZAP2 | -0.1129974 |
| FGFRL1 | -0.1130229 |
| LY6G6C | -0.1130508 |
| CTNNA2 | -0.1130524 |
| TMEM52 | -0.1131115 |
| UTP23 | -0.1131821 |
| ARL17B | -0.1131894 |
| NUDT10 | -0.1132451 |
| HBA2 | -0.1132489 |
| ATP6V1C1 | -0.1132883 |
| OLFML2A | -0.1132918 |
| PYGO1 | -0.1132993 |
| GTF2H5 | -0.1133110 |
| FOPNL | -0.1133383 |
| CUL5 | -0.1133403 |
| GNG13 | -0.1134507 |
| CCNT2 | -0.1134654 |
| C2orf82 | -0.1134943 |
| FAM184B | -0.1135460 |
| SCN1B | -0.1135517 |
| SPAG8 | -0.1135564 |
| DRD2 | -0.1136060 |
| TAF4 | -0.1136166 |
| IGSF10 | -0.1136401 |
| SPRYD7 | -0.1136799 |
| CCDC87 | -0.1137658 |
| MMP24 | -0.1138249 |
| DTWD2 | -0.1138439 |
| CPD | -0.1138675 |
| ADNP | -0.1138989 |
| CCNH | -0.1139140 |
| CCNG2 | -0.1139483 |
| STC1 | -0.1140046 |
| NR2F6 | -0.1140211 |
| RAB3GAP2 | -0.1140614 |
| CYB561D1 | -0.1140887 |
| PEX11B | -0.1141227 |
| MANBAL | -0.1141479 |
| GABRD | -0.1141554 |
| RAB3C | -0.1141647 |
| SNX16 | -0.1142041 |
| NLRP5 | -0.1142085 |
| FAM86B2 | -0.1142157 |
| PIK3C2A | -0.1143274 |
| ZNF558 | -0.1143573 |
| RTN1 | -0.1143758 |
| PRND | -0.1143782 |
| PTPRA | -0.1143988 |
| HPCA | -0.1144466 |
| GTPBP6 | -0.1145076 |
| FLNC | -0.1145368 |
| TGFBR3 | -0.1145423 |
| CAPRIN2 | -0.1145547 |
| EVPLL | -0.1145698 |
| HOOK2 | -0.1145745 |
| KCNMB3 | -0.1145804 |
| ROBO2 | -0.1145830 |
| ZNF709 | -0.1146311 |
| TIGD7 | -0.1146466 |
| MED28 | -0.1146705 |
| PFN4 | -0.1146911 |
| WFDC6 | -0.1147215 |
| METTL12 | -0.1147519 |
| PCBD1 | -0.1148169 |
| PHLDA3 | -0.1148547 |
| NFU1 | -0.1148738 |
| CMTM6 | -0.1148975 |
| RRP15 | -0.1149269 |
| HIRIP3 | -0.1149386 |
| TCF12 | -0.1149479 |
| COL5A3 | -0.1149551 |
| HELZ | -0.1149801 |
| NPFF | -0.1149950 |
| CBLN3 | -0.1150031 |
| HYAL1 | -0.1150177 |
| TMEM30B | -0.1150298 |
| ENKD1 | -0.1150367 |
| ZNF117 | -0.1150401 |
| SH3YL1 | -0.1150509 |
| DNAJB2 | -0.1150707 |
| SPOCK3 | -0.1151272 |
| IKZF5 | -0.1151377 |
| CILP2 | -0.1151934 |
| GPX4 | -0.1152265 |
| FRAT1 | -0.1153389 |
| SLU7 | -0.1153693 |
| C1orf192 | -0.1153779 |
| ATF7 | -0.1154577 |
| PGAP1 | -0.1154843 |
| EDN3 | -0.1155449 |
| DMP1 | -0.1155563 |
| TSPAN31 | -0.1155770 |
| AKAP14 | -0.1155820 |
| C8orf37 | -0.1155980 |
| CFD | -0.1156121 |
| NDUFS4 | -0.1156225 |
| MAP1A | -0.1156401 |
| ZNF337 | -0.1156569 |
| HSD3B1 | -0.1156811 |
| RAE1 | -0.1157228 |
| PAIP2 | -0.1157549 |
| PHF14 | -0.1157634 |
| MRPL10 | -0.1157902 |
| AKAP8L | -0.1157962 |
| PRR12 | -0.1158377 |
| TMEM219 | -0.1158471 |
| UNC5C | -0.1158548 |
| MIPOL1 | -0.1158611 |
| TMEM240 | -0.1158637 |
| EBF3 | -0.1158715 |
| PRDX3 | -0.1158799 |
| MBOAT2 | -0.1158948 |
| BPIFA1 | -0.1159185 |
| BLOC1S1 | -0.1159208 |
| MTCH2 | -0.1159412 |
| SRR | -0.1159515 |
| IER3IP1 | -0.1159551 |
| ATOH8 | -0.1160325 |
| RASSF8 | -0.1160792 |
| MYL7 | -0.1161283 |
| RNF40 | -0.1161449 |
| EIF5 | -0.1161464 |
| NOX5 | -0.1161595 |
| KIAA0195 | -0.1161810 |
| CSPG4 | -0.1163014 |
| CCT2 | -0.1163050 |
| MGST2 | -0.1163191 |
| SLC46A1 | -0.1163281 |
| MROH1 | -0.1163338 |
| GOLGB1 | -0.1163621 |
| MARVELD1 | -0.1163642 |
| SLC38A11 | -0.1163661 |
| MPP5 | -0.1163998 |
| TNRC6A | -0.1164128 |
| SPICE1 | -0.1164410 |
| LPHN1 | -0.1164520 |
| LNX2 | -0.1165081 |
| MOCS1 | -0.1165555 |
| WDR47 | -0.1165639 |
| DBP | -0.1165647 |
| TMEM229A | -0.1165729 |
| FAM208A | -0.1165836 |
| BDNF | -0.1165908 |
| KBTBD7 | -0.1166313 |
| BSDC1 | -0.1166447 |
| TENM2 | -0.1166616 |
| ZNF521 | -0.1166724 |
| TK2 | -0.1166791 |
| LPGAT1 | -0.1166796 |
| ZBTB7A | -0.1166970 |
| KLHL9 | -0.1166992 |
| CENPP | -0.1167067 |
| FIGF | -0.1167639 |
| P2RX4 | -0.1167696 |
| FAH | -0.1167850 |
| STRN3 | -0.1167853 |
| ETFDH | -0.1168053 |
| ATXN3L | -0.1168068 |
| TRMT13 | -0.1168354 |
| PHF20 | -0.1168526 |
| NOXO1 | -0.1168950 |
| NR2F1 | -0.1169485 |
| CRYGS | -0.1169893 |
| PIH1D2 | -0.1170175 |
| THAP1 | -0.1170217 |
| LYPLAL1 | -0.1170295 |
| MAPRE3 | -0.1170632 |
| PRKG1 | -0.1170680 |
| BZW1 | -0.1170922 |
| PLXDC1 | -0.1170958 |
| WDR66 | -0.1171455 |
| SERTM1 | -0.1171704 |
| ZNF217 | -0.1172295 |
| ZNF581 | -0.1172815 |
| ANKRD28 | -0.1172919 |
| SEPT8 | -0.1172972 |
| KCNK6 | -0.1173087 |
| TRIM6 | -0.1173203 |
| SNRNP25 | -0.1173568 |
| TBK1 | -0.1173582 |
| RGN | -0.1173806 |
| ZNF100 | -0.1174267 |
| ASMTL | -0.1174546 |
| ITIH4 | -0.1174569 |
| CACFD1 | -0.1174839 |
| PPT2 | -0.1176233 |
| PXK | -0.1176566 |
| SCRN3 | -0.1176750 |
| BRDT | -0.1176760 |
| TRAPPC8 | -0.1176821 |
| HSPA5 | -0.1177284 |
| HAUS3 | -0.1177881 |
| KIAA0319 | -0.1178940 |
| GGPS1 | -0.1179295 |
| ANKRD40 | -0.1179307 |
| ZBED5 | -0.1179491 |
| NRXN3 | -0.1179698 |
| MPI | -0.1179780 |
| PLEC | -0.1179795 |
| TNFRSF19 | -0.1180033 |
| PLCD3 | -0.1180293 |
| MACF1 | -0.1180610 |
| CRH | -0.1181254 |
| DNAL1 | -0.1181565 |
| C17orf80 | -0.1181686 |
| FTCDNL1 | -0.1181830 |
| AMOTL2 | -0.1181870 |
| RFX1 | -0.1181941 |
| NICN1 | -0.1181988 |
| SPTY2D1 | -0.1182354 |
| DENND4C | -0.1183450 |
| F2R | -0.1183475 |
| CHTF18 | -0.1183541 |
| TUBAL3 | -0.1183797 |
| FAM182B | -0.1184726 |
| MDGA1 | -0.1184730 |
| TAF7 | -0.1185023 |
| PRPH | -0.1185241 |
| AK7 | -0.1185758 |
| PIK3C2G | -0.1185961 |
| RNF186 | -0.1185996 |
| UGT2B15 | -0.1186070 |
| DSTN | -0.1186123 |
| PHLDB1 | -0.1186144 |
| ZNF609 | -0.1186406 |
| CASZ1 | -0.1186890 |
| LAMA5 | -0.1187396 |
| PPM1E | -0.1187398 |
| FOXN4 | -0.1187574 |
| PTGES3L-AARSD1 | -0.1187678 |
| ITGB5 | -0.1187812 |
| ATP1B2 | -0.1188005 |
| ABCA2 | -0.1188031 |
| RSPH3 | -0.1188756 |
| ENTPD3 | -0.1188894 |
| SHC3 | -0.1188970 |
| ZFHX2 | -0.1189011 |
| GGT7 | -0.1189092 |
| GNG12 | -0.1189096 |
| NEFM | -0.1189462 |
| ZNF676 | -0.1189653 |
| PTPDC1 | -0.1189990 |
| ZNF596 | -0.1190019 |
| ZNF559 | -0.1190262 |
| ZNF211 | -0.1190347 |
| ARHGEF25 | -0.1191359 |
| ANG | -0.1191622 |
| CDC14A | -0.1191792 |
| ATP6V1H | -0.1192148 |
| ZFYVE28 | -0.1192257 |
| AHNAK2 | -0.1192357 |
| METTL9 | -0.1192364 |
| CLK1 | -0.1193195 |
| ZNF655 | -0.1193345 |
| FAM149A | -0.1193529 |
| IMPDH2 | -0.1193615 |
| WARS2 | -0.1193860 |
| KCNH2 | -0.1194419 |
| ADAMTS10 | -0.1194816 |
| FHL5 | -0.1195660 |
| ZHX1 | -0.1195710 |
| PCDHB5 | -0.1195884 |
| RALGDS | -0.1196024 |
| CRAMP1L | -0.1196115 |
| CCDC110 | -0.1196460 |
| NTRK3 | -0.1196598 |
| CABP4 | -0.1196712 |
| EDNRB | -0.1197114 |
| ABHD14B | -0.1197416 |
| THNSL1 | -0.1197699 |
| COQ4 | -0.1197756 |
| CRY2 | -0.1197998 |
| HOXB3 | -0.1198556 |
| PDK2 | -0.1200014 |
| IDS | -0.1200064 |
| CEP120 | -0.1200313 |
| ARHGAP24 | -0.1200412 |
| HEMK1 | -0.1200509 |
| VPS39 | -0.1200715 |
| HLF | -0.1200723 |
| MBD6 | -0.1200766 |
| HAPLN2 | -0.1200922 |
| KANK3 | -0.1201115 |
| ZCCHC4 | -0.1201745 |
| HECTD1 | -0.1201789 |
| LYPLA1 | -0.1202213 |
| CEP104 | -0.1202388 |
| DNAAF1 | -0.1203065 |
| TCEAL7 | -0.1203765 |
| ZNF624 | -0.1203847 |
| KLHDC10 | -0.1204384 |
| MMEL1 | -0.1204557 |
| SCNN1G | -0.1204811 |
| MREG | -0.1205036 |
| ARMC4 | -0.1205037 |
| C1orf210 | -0.1205389 |
| MGARP | -0.1205730 |
| ZNF136 | -0.1205907 |
| BLOC1S6 | -0.1206294 |
| KBTBD11 | -0.1207156 |
| COL1A2 | -0.1207248 |
| CCDC115 | -0.1207564 |
| GJC3 | -0.1207896 |
| HN1L | -0.1209867 |
| LDB2 | -0.1209885 |
| ABCG2 | -0.1209924 |
| MIOS | -0.1210029 |
| RNF157 | -0.1210158 |
| ZNF771 | -0.1210224 |
| TCFL5 | -0.1210489 |
| SOCS5 | -0.1210593 |
| IQUB | -0.1210666 |
| NRBP2 | -0.1211157 |
| MATN2 | -0.1211163 |
| AGAP1 | -0.1211298 |
| WDR6 | -0.1211362 |
| ATP9A | -0.1211379 |
| ZSCAN32 | -0.1211491 |
| PIGZ | -0.1211784 |
| NEK9 | -0.1211903 |
| GDF6 | -0.1212020 |
| UBE3A | -0.1212289 |
| EMX2 | -0.1212473 |
| IPPK | -0.1212645 |
| DCDC1 | -0.1213006 |
| HMBOX1 | -0.1213418 |
| GLT8D1 | -0.1213455 |
| ALAD | -0.1213751 |
| PVRL2 | -0.1213826 |
| ADAMTS13 | -0.1213834 |
| HDAC5 | -0.1213870 |
| EGLN2 | -0.1214226 |
| TADA2B | -0.1214312 |
| CHRAC1 | -0.1214316 |
| CNTNAP2 | -0.1214343 |
| AMT | -0.1214369 |
| GULP1 | -0.1214692 |
| NFIC | -0.1215108 |
| BGN | -0.1215279 |
| ZNF24 | -0.1215358 |
| AMIGO1 | -0.1215669 |
| MGRN1 | -0.1215892 |
| NELFA | -0.1216072 |
| PRKAB2 | -0.1216209 |
| AK5 | -0.1216384 |
| SSBP4 | -0.1216604 |
| ZNF547 | -0.1216687 |
| JAM3 | -0.1216752 |
| COL6A3 | -0.1218602 |
| DPY19L1 | -0.1219049 |
| KIAA0754 | -0.1219095 |
| TMEM50B | -0.1219889 |
| HRC | -0.1220609 |
| COPZ2 | -0.1220825 |
| DDO | -0.1220840 |
| MPG | -0.1220879 |
| ITIH3 | -0.1220890 |
| MXI1 | -0.1221088 |
| MIF4GD | -0.1221398 |
| CHRNA10 | -0.1221970 |
| COPG2 | -0.1222233 |
| ZNF615 | -0.1223039 |
| NFYB | -0.1223088 |
| ERI2 | -0.1223270 |
| CROCC | -0.1223354 |
| ARF3 | -0.1223509 |
| C1orf194 | -0.1223643 |
| EIF1AX | -0.1224048 |
| ZNF524 | -0.1224164 |
| NUDT16 | -0.1224258 |
| COL24A1 | -0.1224450 |
| BECN1 | -0.1224863 |
| PTCD2 | -0.1224880 |
| FBXL18 | -0.1224930 |
| SAMD15 | -0.1225144 |
| HIST1H1C | -0.1225716 |
| PLCL1 | -0.1225972 |
| DRC1 | -0.1226286 |
| LRRC29 | -0.1226323 |
| KCNMB2 | -0.1226587 |
| RRAGB | -0.1227137 |
| SLC27A1 | -0.1227404 |
| CREB1 | -0.1227433 |
| C1orf56 | -0.1228132 |
| DENND2A | -0.1228270 |
| DPY19L2 | -0.1228575 |
| FAM161B | -0.1228607 |
| IFT43 | -0.1228897 |
| PPP1R26 | -0.1229088 |
| AGAP2-AS1 | -0.1229635 |
| ZNF720 | -0.1229731 |
| PRSS35 | -0.1229743 |
| TMCO1 | -0.1229817 |
| ETAA1 | -0.1230966 |
| TEX12 | -0.1232512 |
| RALGAPB | -0.1233095 |
| TOX4 | -0.1233186 |
| ZNF436 | -0.1233632 |
| ZDHHC22 | -0.1233860 |
| OCIAD1 | -0.1233909 |
| ZCCHC13 | -0.1234355 |
| SUV420H2 | -0.1234554 |
| RAB3B | -0.1234629 |
| DFNB59 | -0.1234761 |
| TDGF1 | -0.1234853 |
| ERGIC1 | -0.1235111 |
| SRSF1 | -0.1235785 |
| TDRD9 | -0.1235902 |
| BOD1 | -0.1236006 |
| SLMO1 | -0.1236305 |
| RNPEP | -0.1236461 |
| LRTOMT | -0.1237078 |
| FBN2 | -0.1237251 |
| ZFYVE16 | -0.1237644 |
| ZNF770 | -0.1237812 |
| DET1 | -0.1238464 |
| ARPP19 | -0.1239485 |
| FAM213B | -0.1239607 |
| EXOC6 | -0.1240006 |
| NDRG3 | -0.1240040 |
| TMEM190 | -0.1240376 |
| FAM219B | -0.1240378 |
| CCDC83 | -0.1241117 |
| RNF14 | -0.1241595 |
| SWSAP1 | -0.1241700 |
| LAMC1 | -0.1242062 |
| SARM1 | -0.1242600 |
| EEPD1 | -0.1243404 |
| GOLGA8F | -0.1243416 |
| DYNC2LI1 | -0.1244244 |
| CCDC158 | -0.1244477 |
| LIMA1 | -0.1244637 |
| C1QTNF5 | -0.1245197 |
| MFSD6L | -0.1245223 |
| ENPEP | -0.1245228 |
| EAPP | -0.1245617 |
| CD320 | -0.1245826 |
| ITGA2 | -0.1245994 |
| PDPK1 | -0.1246158 |
| ARHGEF26 | -0.1246584 |
| GAD1 | -0.1246671 |
| CTNND1 | -0.1246742 |
| PHF20L1 | -0.1246874 |
| APC2 | -0.1246965 |
| ITPR1 | -0.1247132 |
| SPIRE1 | -0.1247396 |
| ACAD11 | -0.1247511 |
| CCDC121 | -0.1247552 |
| ZNF543 | -0.1247578 |
| ZNF621 | -0.1247841 |
| TRAPPC9 | -0.1248885 |
| ATP5G2 | -0.1248934 |
| SLC16A9 | -0.1249549 |
| C8orf48 | -0.1249697 |
| ZNF346 | -0.1249785 |
| AP4E1 | -0.1250154 |
| TMEM229B | -0.1250291 |
| TMEM213 | -0.1250758 |
| STPG1 | -0.1251225 |
| TTC23L | -0.1251238 |
| TRUB1 | -0.1251615 |
| RECQL4 | -0.1251729 |
| ZNF788 | -0.1251856 |
| PTPRM | -0.1252173 |
| FLYWCH1 | -0.1252208 |
| CREBZF | -0.1252849 |
| IL11 | -0.1253137 |
| ZNF737 | -0.1253285 |
| HIST2H2AA4 | -0.1254339 |
| ATRNL1 | -0.1254583 |
| COG7 | -0.1254740 |
| SRPK2 | -0.1254766 |
| DKK2 | -0.1254778 |
| HOXC5 | -0.1255274 |
| DOC2A | -0.1255550 |
| MARC2 | -0.1256087 |
| CES4A | -0.1256403 |
| SYNJ2BP | -0.1256582 |
| NCKAP5 | -0.1256607 |
| ADAM2 | -0.1256639 |
| ERBB2IP | -0.1257278 |
| ASAH1 | -0.1257286 |
| SPINT1 | -0.1257579 |
| ERMAP | -0.1257662 |
| C18orf32 | -0.1257777 |
| TOM1L2 | -0.1258050 |
| THSD7A | -0.1258301 |
| TRO | -0.1258431 |
| CCDC101 | -0.1258780 |
| AGAP9 | -0.1259005 |
| XKR6 | -0.1259098 |
| RBM5 | -0.1259183 |
| AVIL | -0.1259193 |
| ZER1 | -0.1259456 |
| TTC30A | -0.1260576 |
| TRIM4 | -0.1261888 |
| MECOM | -0.1262089 |
| ZNF148 | -0.1262153 |
| AHCYL1 | -0.1262311 |
| PCGF3 | -0.1262388 |
| PILRB | -0.1262885 |
| HOXB2 | -0.1263711 |
| TIPARP | -0.1263863 |
| TMEM68 | -0.1263897 |
| C6 | -0.1264071 |
| CDH19 | -0.1264136 |
| BCORL1 | -0.1264148 |
| ANKRD52 | -0.1264441 |
| KIAA1549 | -0.1264840 |
| TLE3 | -0.1265127 |
| SCRN2 | -0.1265218 |
| SLC26A3 | -0.1265369 |
| FGF12 | -0.1265557 |
| PIGG | -0.1265802 |
| GRINA | -0.1265834 |
| SKIV2L2 | -0.1266105 |
| FAT3 | -0.1266132 |
| SRRM3 | -0.1266165 |
| HOMER2 | -0.1266384 |
| HOXB6 | -0.1266441 |
| LCMT1 | -0.1266517 |
| RAB11FIP5 | -0.1266773 |
| FAM154B | -0.1266838 |
| EXOC2 | -0.1267036 |
| ANKRD39 | -0.1267490 |
| MEOX2 | -0.1267750 |
| CYP26A1 | -0.1268319 |
| SORCS3 | -0.1268607 |
| RICTOR | -0.1268669 |
| BOD1L1 | -0.1268784 |
| KAT6A | -0.1269209 |
| SAMD12 | -0.1269775 |
| CSN3 | -0.1270396 |
| PPP1R32 | -0.1270453 |
| NRN1L | -0.1270662 |
| FAM162B | -0.1271703 |
| ACY1 | -0.1272218 |
| ACMSD | -0.1272549 |
| BEX2 | -0.1272635 |
| RNF212 | -0.1272900 |
| RAB27B | -0.1273206 |
| DGKQ | -0.1273560 |
| IFT74 | -0.1273981 |
| C8orf33 | -0.1275769 |
| FBXO44 | -0.1276025 |
| PKP3 | -0.1276112 |
| C6orf1 | -0.1276422 |
| THSD1 | -0.1276807 |
| PDHB | -0.1276844 |
| AP1M2 | -0.1277507 |
| HOXC13 | -0.1278201 |
| SPAG16 | -0.1278926 |
| ADSSL1 | -0.1279197 |
| AAMDC | -0.1279286 |
| ZNF397 | -0.1279322 |
| XRRA1 | -0.1279456 |
| FAM19A2 | -0.1279564 |
| FAM120AOS | -0.1280090 |
| ARL13B | -0.1280433 |
| PPM1A | -0.1280689 |
| TEKT5 | -0.1281107 |
| FAM134A | -0.1281385 |
| EEF1D | -0.1281456 |
| WBP11 | -0.1281731 |
| RIC3 | -0.1281868 |
| JKAMP | -0.1282272 |
| THBS1 | -0.1282720 |
| ACCS | -0.1282885 |
| KCNH6 | -0.1283757 |
| ZNF385B | -0.1283997 |
| RHOXF1 | -0.1284513 |
| TMEM187 | -0.1285010 |
| PPP1R3E | -0.1285112 |
| TMF1 | -0.1285137 |
| SMN1 | -0.1285561 |
| CCDC19 | -0.1285572 |
| NBPF9 | -0.1285795 |
| ZNF839 | -0.1286526 |
| KIAA0430 | -0.1286558 |
| FAM221A | -0.1286673 |
| MORN1 | -0.1286713 |
| SH3D19 | -0.1286984 |
| GALNT5 | -0.1287021 |
| DUT | -0.1287214 |
| THTPA | -0.1287439 |
| FBXO21 | -0.1287863 |
| NEK1 | -0.1289364 |
| N4BP2 | -0.1289555 |
| NARFL | -0.1289658 |
| USP14 | -0.1289891 |
| NPTX1 | -0.1290017 |
| SEPW1 | -0.1290053 |
| TMEM120B | -0.1290189 |
| COG2 | -0.1290470 |
| ZNF234 | -0.1290500 |
| TAS2R14 | -0.1290609 |
| ANKEF1 | -0.1291112 |
| PRR22 | -0.1291487 |
| MBD5 | -0.1291995 |
| GFER | -0.1292311 |
| ANKMY1 | -0.1292339 |
| PABPC5 | -0.1292523 |
| ECE1 | -0.1293180 |
| NPAP1 | -0.1293308 |
| NEK11 | -0.1293509 |
| FAM189A2 | -0.1294118 |
| ZC2HC1C | -0.1294495 |
| SPATA6L | -0.1294520 |
| PODN | -0.1294609 |
| PLN | -0.1294618 |
| RTEL1 | -0.1295331 |
| PDGFRL | -0.1295683 |
| VPS25 | -0.1296027 |
| RNLS | -0.1296422 |
| SNCA | -0.1296894 |
| TEK | -0.1297202 |
| MXRA8 | -0.1297331 |
| BACE1 | -0.1297460 |
| ZNF692 | -0.1298950 |
| KIAA1468 | -0.1299066 |
| ADCK5 | -0.1299702 |
| ZFAND1 | -0.1299858 |
| MAP6D1 | -0.1301160 |
| PPP4R4 | -0.1301199 |
| BCL2L2 | -0.1301227 |
| KLB | -0.1301712 |
| PTK6 | -0.1301771 |
| ZNF844 | -0.1302328 |
| DEAF1 | -0.1302556 |
| PKDCC | -0.1303115 |
| NCDN | -0.1303748 |
| KATNBL1 | -0.1305048 |
| BLVRA | -0.1305509 |
| DHRS1 | -0.1305847 |
| SBP1 | -0.1306049 |
| MAP3K10 | -0.1306822 |
| SYCE1 | -0.1307461 |
| HEATR5B | -0.1307660 |
| PLK5 | -0.1307687 |
| HOXC9 | -0.1308145 |
| TMEM115 | -0.1308295 |
| MDM2 | -0.1308501 |
| SPARC | -0.1308832 |
| HTR2B | -0.1309213 |
| SPON2 | -0.1309311 |
| JAM2 | -0.1310100 |
| PPP2R5A | -0.1310131 |
| UVRAG | -0.1310144 |
| RAMP2 | -0.1310432 |
| UTP14C | -0.1310492 |
| TRAF7 | -0.1310627 |
| NAV1 | -0.1310803 |
| ARFIP1 | -0.1311597 |
| P4HA3 | -0.1311748 |
| ADD1 | -0.1311829 |
| CSNK1A1 | -0.1312169 |
| FAM193A | -0.1312587 |
| AMDHD2 | -0.1312786 |
| CRADD | -0.1313055 |
| MAP4K3 | -0.1313089 |
| HGSNAT | -0.1313095 |
| IDNK | -0.1313165 |
| KMT2D | -0.1313321 |
| PPP1R37 | -0.1313526 |
| ADAMTS8 | -0.1313723 |
| SFRP4 | -0.1313978 |
| ULK4 | -0.1314267 |
| RLN1 | -0.1314436 |
| DDR1 | -0.1315456 |
| UBR1 | -0.1315800 |
| NSA2 | -0.1315833 |
| KIAA0087 | -0.1316080 |
| ARHGAP35 | -0.1316915 |
| TOB1 | -0.1316980 |
| ACOX3 | -0.1317315 |
| PRLR | -0.1317392 |
| TMEM230 | -0.1318241 |
| TAF9B | -0.1318342 |
| PKD2 | -0.1319055 |
| PARD6A | -0.1319478 |
| HSF4 | -0.1319676 |
| LSM1 | -0.1319736 |
| COX4I2 | -0.1320352 |
| DNAJC24 | -0.1321177 |
| CHRNA9 | -0.1322056 |
| TWF1 | -0.1322506 |
| ADAM32 | -0.1322618 |
| RNF111 | -0.1323832 |
| ABCG1 | -0.1323920 |
| ITGBL1 | -0.1323934 |
| SPRYD4 | -0.1324468 |
| PF4 | -0.1324550 |
| TRAPPC2 | -0.1325047 |
| RMND5B | -0.1325108 |
| EIF3H | -0.1325198 |
| CLN8 | -0.1325391 |
| OVOL2 | -0.1325655 |
| SCAND1 | -0.1326206 |
| LETMD1 | -0.1326358 |
| CATSPER3 | -0.1326371 |
| VPS13B | -0.1327693 |
| PIGF | -0.1327823 |
| PCDH19 | -0.1327848 |
| RWDD4 | -0.1328607 |
| IZUMO4 | -0.1329094 |
| EDA2R | -0.1329309 |
| BRAT1 | -0.1329436 |
| DNAJC16 | -0.1329604 |
| EPS8L1 | -0.1329876 |
| ZNF281 | -0.1330177 |
| KIAA1328 | -0.1330300 |
| ABHD12B | -0.1330749 |
| UQCRQ | -0.1330933 |
| SEPT10 | -0.1331071 |
| KIAA0556 | -0.1331507 |
| TTC28 | -0.1331641 |
| TANC2 | -0.1331793 |
| ZNF587B | -0.1332065 |
| NKX3-1 | -0.1332938 |
| NEURL2 | -0.1334611 |
| SMCR8 | -0.1334651 |
| HIST1H2AM | -0.1335199 |
| TUSC2 | -0.1335873 |
| IL24 | -0.1336192 |
| TEX264 | -0.1336296 |
| TRPM7 | -0.1337220 |
| CYB5D1 | -0.1337306 |
| ANGEL2 | -0.1337331 |
| PPFIBP1 | -0.1338805 |
| TMEM246 | -0.1338830 |
| MS4A15 | -0.1339386 |
| TEX14 | -0.1339803 |
| MSX2 | -0.1340104 |
| C11orf88 | -0.1340116 |
| ADAMTS19 | -0.1340745 |
| STON1 | -0.1341353 |
| DHX29 | -0.1341599 |
| PLAC1 | -0.1342311 |
| EPHA3 | -0.1342442 |
| TCTN2 | -0.1342473 |
| STK32C | -0.1342628 |
| HOGA1 | -0.1343564 |
| ABHD14A | -0.1343627 |
| TMEM9 | -0.1343889 |
| HOXC10 | -0.1344297 |
| C9orf50 | -0.1344431 |
| SPATA5L1 | -0.1344489 |
| USP8 | -0.1344999 |
| C16orf58 | -0.1345478 |
| EPN2 | -0.1345953 |
| SERPINI1 | -0.1346009 |
| LRP4 | -0.1346584 |
| ZNF208 | -0.1346652 |
| IQCA1 | -0.1346710 |
| VIPR2 | -0.1346736 |
| TERF1 | -0.1346902 |
| IKBKB | -0.1347259 |
| WBSCR28 | -0.1347432 |
| FAM104A | -0.1347555 |
| RAMP3 | -0.1347738 |
| FAM216B | -0.1348121 |
| ZNF37A | -0.1348419 |
| SPTBN4 | -0.1348925 |
| GDI1 | -0.1349278 |
| TIMM10B | -0.1349824 |
| CYTH3 | -0.1350292 |
| RUFY2 | -0.1350521 |
| CRTAP | -0.1351575 |
| CXorf23 | -0.1351884 |
| ZNF174 | -0.1352078 |
| OSGEPL1 | -0.1352778 |
| KATNAL1 | -0.1352915 |
| MSH3 | -0.1353168 |
| ASPA | -0.1353642 |
| FGF10 | -0.1353830 |
| ARV1 | -0.1354521 |
| C20orf85 | -0.1354653 |
| GLUL | -0.1354944 |
| C1QTNF7 | -0.1354969 |
| RHOC | -0.1356393 |
| CRYZL1 | -0.1357104 |
| TESC | -0.1357229 |
| SENP6 | -0.1357388 |
| NPY5R | -0.1357425 |
| GSTM4 | -0.1357726 |
| LETM2 | -0.1358030 |
| GJC2 | -0.1358075 |
| PNPLA7 | -0.1358688 |
| ATG14 | -0.1358821 |
| SLC52A3 | -0.1359195 |
| SPSB3 | -0.1359621 |
| NDNF | -0.1360096 |
| ATG2B | -0.1360539 |
| KLF17 | -0.1360634 |
| HDDC3 | -0.1360671 |
| MUM1 | -0.1361555 |
| ZNF862 | -0.1362079 |
| RASA1 | -0.1362197 |
| MOAP1 | -0.1362212 |
| ANKRD13D | -0.1362449 |
| PFKFB1 | -0.1362517 |
| CPA6 | -0.1362889 |
| F12 | -0.1363242 |
| MATR3 | -0.1363553 |
| ANO5 | -0.1363925 |
| PDE11A | -0.1363977 |
| RAB11A | -0.1364417 |
| BMI1 | -0.1364720 |
| MAGIX | -0.1365323 |
| SLC12A2 | -0.1365652 |
| CRIP2 | -0.1366128 |
| DIXDC1 | -0.1367115 |
| XAGE1B | -0.1367545 |
| ZNF716 | -0.1368082 |
| PGAP2 | -0.1368184 |
| FAM200B | -0.1368603 |
| CHST1 | -0.1368832 |
| ZNF311 | -0.1368834 |
| CCDC136 | -0.1368951 |
| R3HDM2 | -0.1369489 |
| NUDCD3 | -0.1369499 |
| LINGO1 | -0.1369719 |
| PNPO | -0.1369721 |
| TTC30B | -0.1370231 |
| PRELID2 | -0.1370642 |
| C16orf62 | -0.1370660 |
| CYP2R1 | -0.1371032 |
| ZNF549 | -0.1371147 |
| NDUFAF3 | -0.1371295 |
| ECM2 | -0.1371577 |
| FADD | -0.1371844 |
| NME7 | -0.1372274 |
| ERMARD | -0.1373046 |
| IL1RAPL1 | -0.1373350 |
| NUAK1 | -0.1373412 |
| DDX46 | -0.1373852 |
| ZKSCAN1 | -0.1374720 |
| MED21 | -0.1374843 |
| NBPF11 | -0.1375219 |
| C7orf63 | -0.1375859 |
| LAMTOR3 | -0.1376273 |
| CALCA | -0.1376808 |
| NRIP3 | -0.1376897 |
| CAPRIN1 | -0.1377021 |
| MRPS34 | -0.1377303 |
| PALLD | -0.1378058 |
| GOLGA6C | -0.1378167 |
| N4BP3 | -0.1378550 |
| C2orf27A | -0.1378603 |
| ZBTB48 | -0.1378645 |
| SHISA6 | -0.1378722 |
| KBTBD6 | -0.1379355 |
| WDR63 | -0.1379424 |
| FAM175A | -0.1379712 |
| DCAF17 | -0.1380069 |
| TBX15 | -0.1380586 |
| HIP1 | -0.1380797 |
| ADCY5 | -0.1381418 |
| TRAPPC2P1 | -0.1382343 |
| CUL3 | -0.1382457 |
| HOXD3 | -0.1383079 |
| INHBB | -0.1383152 |
| MAPK3 | -0.1383487 |
| IGHMBP2 | -0.1384103 |
| HNRNPDL | -0.1384764 |
| COL8A1 | -0.1385192 |
| STXBP2 | -0.1385398 |
| SH3PXD2A | -0.1385658 |
| ZNF584 | -0.1386005 |
| SHPK | -0.1386399 |
| DACH2 | -0.1386470 |
| SLC30A9 | -0.1386744 |
| GDF10 | -0.1387006 |
| SGCA | -0.1387243 |
| ZDBF2 | -0.1387282 |
| RNF141 | -0.1388268 |
| MSX1 | -0.1388616 |
| LRRC57 | -0.1389086 |
| RSL1D1 | -0.1389575 |
| KIF3B | -0.1389854 |
| TMA7 | -0.1390933 |
| WBP1 | -0.1392153 |
| SPINK13 | -0.1393480 |
| RALGPS2 | -0.1393743 |
| CHD6 | -0.1393915 |
| BRD8 | -0.1394289 |
| PACS2 | -0.1394309 |
| LEO1 | -0.1394729 |
| CYB5A | -0.1394801 |
| GAB2 | -0.1395045 |
| PACRGL | -0.1395275 |
| MBOAT1 | -0.1395348 |
| PPAP2A | -0.1396782 |
| SOX3 | -0.1397816 |
| KIAA0319L | -0.1398210 |
| POC1B | -0.1398682 |
| SLX4IP | -0.1398822 |
| GTF2IRD2B | -0.1398877 |
| TFAP2A | -0.1398926 |
| SERF2 | -0.1399027 |
| RPRD1B | -0.1399153 |
| NIPA1 | -0.1400021 |
| NPEPPS | -0.1400070 |
| PRPF39 | -0.1400700 |
| SRP14 | -0.1400726 |
| IP6K2 | -0.1400790 |
| KISS1R | -0.1401131 |
| SMR3B | -0.1401166 |
| KAZALD1 | -0.1401241 |
| SH2B1 | -0.1401421 |
| TRMT1L | -0.1401938 |
| CCDC34 | -0.1403509 |
| HMCN1 | -0.1404515 |
| C5orf15 | -0.1404668 |
| GOLGA6L4 | -0.1405124 |
| IRS2 | -0.1405816 |
| FAM98C | -0.1405922 |
| C20orf195 | -0.1406927 |
| BAIAP2 | -0.1406988 |
| ZNF175 | -0.1407654 |
| TAF9 | -0.1408795 |
| ANKRD30B | -0.1408918 |
| ZNF689 | -0.1408942 |
| ZNF799 | -0.1409766 |
| SIGLEC15 | -0.1411493 |
| ZDHHC2 | -0.1411621 |
| RGS7 | -0.1413058 |
| FAM156A | -0.1413217 |
| TRIM33 | -0.1413277 |
| FAM124B | -0.1414678 |
| UBE3B | -0.1414840 |
| EEA1 | -0.1415092 |
| CPT1B | -0.1417027 |
| CTR9 | -0.1417104 |
| STARD13 | -0.1417181 |
| OTUD7A | -0.1417585 |
| LRRC70 | -0.1418066 |
| CANT1 | -0.1418223 |
| ST3GAL1 | -0.1418597 |
| TSG101 | -0.1419052 |
| POLD4 | -0.1419060 |
| CD151 | -0.1419076 |
| ZNF572 | -0.1419181 |
| RP1 | -0.1420245 |
| EFHC1 | -0.1420590 |
| NANOS3 | -0.1421218 |
| PER3 | -0.1421516 |
| SLC10A1 | -0.1422065 |
| ITGA10 | -0.1422196 |
| NEIL2 | -0.1422208 |
| PCDHA11 | -0.1422468 |
| NFS1 | -0.1422543 |
| HBB | -0.1422693 |
| KIAA0141 | -0.1423013 |
| LRRIQ1 | -0.1423777 |
| PAMR1 | -0.1424042 |
| CAPN9 | -0.1424228 |
| HOXB5 | -0.1424999 |
| MPV17L | -0.1425073 |
| KIAA1683 | -0.1426517 |
| ERO1LB | -0.1426781 |
| XPA | -0.1427319 |
| RAB30 | -0.1427328 |
| CAP2 | -0.1427470 |
| KIF13B | -0.1428184 |
| CAMSAP2 | -0.1428250 |
| NPIPA1 | -0.1429012 |
| SPIDR | -0.1429390 |
| MTMR7 | -0.1429465 |
| OSBPL6 | -0.1429612 |
| ZNF675 | -0.1429649 |
| CLEC18B | -0.1431082 |
| ZNF442 | -0.1431812 |
| NPTN | -0.1431954 |
| FAM102B | -0.1433952 |
| TJP3 | -0.1434121 |
| ARHGAP32 | -0.1434641 |
| ZSWIM6 | -0.1434644 |
| TMEM80 | -0.1434773 |
| ADIPOQ | -0.1434860 |
| MRPS36 | -0.1435209 |
| ZNF329 | -0.1436065 |
| FBXO41 | -0.1436551 |
| NAP1L1 | -0.1437031 |
| KIAA1522 | -0.1437051 |
| CHST9 | -0.1437375 |
| PIK3R1 | -0.1437440 |
| GSTM2 | -0.1437463 |
| SGCG | -0.1437645 |
| SEMA5A | -0.1437827 |
| HOXC8 | -0.1437987 |
| GSDMD | -0.1438192 |
| SFI1 | -0.1438411 |
| RPL22 | -0.1438456 |
| CHRNG | -0.1438572 |
| COX20 | -0.1439254 |
| ZSCAN29 | -0.1439623 |
| CLUL1 | -0.1439987 |
| FAM149B1 | -0.1440156 |
| SLX4 | -0.1440238 |
| SLC24A1 | -0.1441510 |
| FGGY | -0.1441511 |
| MPPED1 | -0.1441635 |
| AFF4 | -0.1441699 |
| STON2 | -0.1441942 |
| TNN | -0.1442200 |
| GLYR1 | -0.1442721 |
| UNC119B | -0.1442917 |
| HIST1H2AD | -0.1443125 |
| CCBL1 | -0.1445615 |
| SORCS2 | -0.1445755 |
| ANO9 | -0.1445943 |
| GPHN | -0.1446015 |
| PNMA1 | -0.1447077 |
| SCRIB | -0.1447114 |
| FBXO38 | -0.1447461 |
| FAM204A | -0.1447505 |
| GPAM | -0.1447900 |
| SCN3B | -0.1449187 |
| CACNB2 | -0.1449986 |
| ABCA9 | -0.1450204 |
| ZNF664 | -0.1450262 |
| NPRL2 | -0.1450352 |
| LRRIQ3 | -0.1450719 |
| KCNJ11 | -0.1451151 |
| ZFYVE27 | -0.1451328 |
| TMEM47 | -0.1451439 |
| GDF9 | -0.1451450 |
| VPS41 | -0.1451839 |
| FAT4 | -0.1452114 |
| FUNDC1 | -0.1454537 |
| TMEM205 | -0.1454552 |
| TIGD5 | -0.1454807 |
| PSCA | -0.1455077 |
| TSC2 | -0.1455618 |
| IFT80 | -0.1455891 |
| SPIN3 | -0.1455913 |
| DNAJC6 | -0.1456241 |
| CASKIN2 | -0.1456403 |
| DNAI1 | -0.1457842 |
| BRWD1 | -0.1458292 |
| BCDIN3D | -0.1458855 |
| AFMID | -0.1459704 |
| CYP4V2 | -0.1460128 |
| COL10A1 | -0.1461759 |
| CDK17 | -0.1462267 |
| LPCAT3 | -0.1462461 |
| IQCH | -0.1463190 |
| DAPL1 | -0.1463249 |
| ZFHX3 | -0.1463776 |
| MDM1 | -0.1464074 |
| ZNF34 | -0.1464327 |
| MAP3K1 | -0.1465138 |
| ANKRD20A2 | -0.1465925 |
| ZNF595 | -0.1466390 |
| SRRM2 | -0.1467271 |
| ZNF30 | -0.1467352 |
| TRIM7 | -0.1467806 |
| PAM16 | -0.1467831 |
| XYLT1 | -0.1467886 |
| MRPS27 | -0.1467949 |
| ANGPTL7 | -0.1468651 |
| VIPR1 | -0.1468674 |
| TMEM125 | -0.1468737 |
| PCNXL4 | -0.1468802 |
| ARRB1 | -0.1469883 |
| XBP1 | -0.1469894 |
| C12orf73 | -0.1469964 |
| MXD1 | -0.1470443 |
| IMMP2L | -0.1470849 |
| ABI2 | -0.1471592 |
| COX7C | -0.1472028 |
| HNRNPH2 | -0.1472904 |
| PIEZO2 | -0.1473023 |
| RHOJ | -0.1473063 |
| LUC7L | -0.1473097 |
| RALGAPA1 | -0.1473690 |
| ANKMY2 | -0.1474012 |
| MLST8 | -0.1474570 |
| FAM135B | -0.1474689 |
| APPL1 | -0.1474722 |
| FAM114A2 | -0.1474961 |
| REEP1 | -0.1474962 |
| SOX17 | -0.1475460 |
| SH3BGRL | -0.1476580 |
| SERINC3 | -0.1476605 |
| RIC8B | -0.1477107 |
| HS3ST5 | -0.1477432 |
| LMX1B | -0.1477506 |
| TP53BP1 | -0.1477735 |
| SPA17 | -0.1477773 |
| RPS23 | -0.1478152 |
| TMEM184A | -0.1478237 |
| C10orf107 | -0.1478524 |
| BMPR2 | -0.1478564 |
| SPHAR | -0.1478644 |
| ZNF573 | -0.1480191 |
| STX16 | -0.1481402 |
| CDKL2 | -0.1481551 |
| EFCAB1 | -0.1481827 |
| SIAE | -0.1481918 |
| PDE7B | -0.1482085 |
| DEXI | -0.1482526 |
| SHARPIN | -0.1482638 |
| CLIP3 | -0.1482660 |
| BMP4 | -0.1483009 |
| PTOV1 | -0.1483009 |
| LDLRAD3 | -0.1483233 |
| TYW5 | -0.1483462 |
| CISH | -0.1486228 |
| TMEM260 | -0.1486305 |
| PFDN5 | -0.1486310 |
| LRRN3 | -0.1486478 |
| PAN2 | -0.1486608 |
| CLEC3B | -0.1488622 |
| SMIM14 | -0.1488689 |
| ARID2 | -0.1488980 |
| SH3GLB2 | -0.1489867 |
| TMTC3 | -0.1489917 |
| KLHL3 | -0.1490406 |
| NAT6 | -0.1490625 |
| FAM171B | -0.1490905 |
| MAGEL2 | -0.1491116 |
| APPBP2 | -0.1491159 |
| ACOT2 | -0.1491634 |
| CCDC159 | -0.1492117 |
| TMEM136 | -0.1493028 |
| TCTA | -0.1493056 |
| SLC25A41 | -0.1493541 |
| FAM83H | -0.1493717 |
| COX19 | -0.1494116 |
| PHYHIP | -0.1494474 |
| SMYD3 | -0.1494817 |
| AGGF1 | -0.1495798 |
| HYI | -0.1495874 |
| CELF6 | -0.1496058 |
| LRRC8E | -0.1496677 |
| DDAH2 | -0.1496951 |
| PCDHB16 | -0.1497103 |
| THNSL2 | -0.1497131 |
| LYRM7 | -0.1497188 |
| DTD2 | -0.1497240 |
| SLC27A5 | -0.1497504 |
| PPFIA4 | -0.1497830 |
| TNRC6C | -0.1498314 |
| KLHL12 | -0.1498878 |
| ZC2HC1A | -0.1499759 |
| NUDT13 | -0.1500257 |
| HSD17B8 | -0.1501936 |
| DPH6 | -0.1502658 |
| PEX2 | -0.1502700 |
| ADHFE1 | -0.1503914 |
| NOL3 | -0.1503951 |
| ATP5I | -0.1504390 |
| H1F0 | -0.1504691 |
| EMP2 | -0.1504950 |
| KRT8 | -0.1505114 |
| EDNRA | -0.1505199 |
| TSNAX | -0.1505224 |
| MPDZ | -0.1506480 |
| ZNF365 | -0.1508132 |
| PAGR1 | -0.1509031 |
| IGSF22 | -0.1509090 |
| PAH | -0.1509965 |
| PRPH2 | -0.1511373 |
| MMP23B | -0.1513226 |
| GPR135 | -0.1513529 |
| PRPF40B | -0.1514040 |
| KANSL1 | -0.1514208 |
| SUSD4 | -0.1514365 |
| LYRM9 | -0.1515979 |
| CAPN13 | -0.1516165 |
| ARTN | -0.1516594 |
| MYEOV2 | -0.1517181 |
| AHRR | -0.1517416 |
| SH3BGR | -0.1517454 |
| RHBDD2 | -0.1517630 |
| NPIPB5 | -0.1517756 |
| BAG3 | -0.1518020 |
| MEGF8 | -0.1518176 |
| COX7A1 | -0.1518889 |
| SH3RF1 | -0.1519802 |
| MDH1B | -0.1519924 |
| PRICKLE2 | -0.1520224 |
| NXPH3 | -0.1520232 |
| ZNF428 | -0.1521064 |
| PKIG | -0.1521130 |
| ALKBH7 | -0.1521194 |
| POC5 | -0.1521282 |
| NAPB | -0.1521388 |
| TMEM8B | -0.1521526 |
| RAD17 | -0.1521564 |
| SEMA4F | -0.1521564 |
| HCN3 | -0.1521646 |
| MED25 | -0.1521877 |
| GLUD1 | -0.1521972 |
| ZNF7 | -0.1522555 |
| FNDC5 | -0.1522924 |
| CASP16 | -0.1523201 |
| ZNF823 | -0.1523396 |
| ZNF606 | -0.1523459 |
| CRMP1 | -0.1523538 |
| LRRC23 | -0.1523828 |
| PEX19 | -0.1524007 |
| EFCAB7 | -0.1524457 |
| STUB1 | -0.1525674 |
| PKP4 | -0.1525986 |
| ZNF280D | -0.1526889 |
| RIIAD1 | -0.1527465 |
| ZNF439 | -0.1528033 |
| ALG8 | -0.1529485 |
| SHANK2 | -0.1529847 |
| LRRC39 | -0.1529917 |
| COA3 | -0.1530512 |
| UBR3 | -0.1530597 |
| FAM195A | -0.1532016 |
| TAC1 | -0.1532201 |
| FNIP1 | -0.1532953 |
| WDR90 | -0.1533182 |
| CACNG6 | -0.1534409 |
| INMT | -0.1534920 |
| KCND3 | -0.1535748 |
| TBC1D12 | -0.1535783 |
| PAXIP1 | -0.1536165 |
| EME2 | -0.1536438 |
| SMIM11 | -0.1536642 |
| THUMPD1 | -0.1536753 |
| PHC3 | -0.1537704 |
| ALDH3A2 | -0.1537820 |
| FPGT | -0.1539099 |
| ZNF417 | -0.1539467 |
| ZDHHC17 | -0.1540462 |
| RRM2B | -0.1540697 |
| MRAP | -0.1540841 |
| CCDC40 | -0.1540997 |
| ATP6V1G2 | -0.1541425 |
| TMTC2 | -0.1541594 |
| TSTD1 | -0.1541645 |
| TMEM200B | -0.1541808 |
| POLR3E | -0.1542024 |
| ZNF721 | -0.1542756 |
| EIF3C | -0.1542869 |
| METTL20 | -0.1543212 |
| ZNF350 | -0.1543222 |
| PCBD2 | -0.1543733 |
| BRINP2 | -0.1544048 |
| MNAT1 | -0.1544640 |
| NUDT4 | -0.1544762 |
| BTNL9 | -0.1545018 |
| PER2 | -0.1545765 |
| ZEB1 | -0.1548013 |
| CSPP1 | -0.1548245 |
| PPAPDC1B | -0.1548326 |
| PPP2R2C | -0.1549504 |
| KIAA1107 | -0.1549909 |
| AK8 | -0.1550640 |
| KCNMB4 | -0.1550984 |
| ZNF334 | -0.1551022 |
| MUSTN1 | -0.1551045 |
| ZNF226 | -0.1551200 |
| RUNDC3B | -0.1551568 |
| RBM47 | -0.1551851 |
| BBS2 | -0.1552035 |
| RUNX1 | -0.1552394 |
| IRX5 | -0.1552461 |
| SYNJ2 | -0.1552626 |
| FAM172A | -0.1553071 |
| TIGD6 | -0.1553531 |
| STXBP1 | -0.1553783 |
| MTMR9 | -0.1553899 |
| PELI3 | -0.1553926 |
| FAM86A | -0.1554926 |
| ME3 | -0.1555096 |
| ZHX3 | -0.1556317 |
| KLHDC2 | -0.1556626 |
| ZNF540 | -0.1556915 |
| CARF | -0.1557101 |
| AKR7A2 | -0.1557244 |
| TM7SF2 | -0.1558386 |
| CHURC1 | -0.1559348 |
| RPGR | -0.1559623 |
| PIGQ | -0.1560081 |
| CTTN | -0.1560268 |
| CLDN12 | -0.1560343 |
| CEP68 | -0.1560757 |
| TLE2 | -0.1560957 |
| MESP1 | -0.1561154 |
| TRAPPC6A | -0.1561327 |
| C2orf73 | -0.1562353 |
| STEAP2 | -0.1563153 |
| ZNF706 | -0.1563372 |
| WDR96 | -0.1563595 |
| BLOC1S4 | -0.1565400 |
| ZRANB1 | -0.1565479 |
| SERF1B | -0.1566912 |
| PIGV | -0.1567102 |
| CCNL2 | -0.1567680 |
| ENDOV | -0.1568667 |
| FAR1 | -0.1569363 |
| SLMAP | -0.1570668 |
| GNG11 | -0.1570988 |
| PHACTR3 | -0.1571040 |
| HDHD2 | -0.1571091 |
| CCDC8 | -0.1571963 |
| KAT6B | -0.1571972 |
| SCN7A | -0.1572410 |
| NBR1 | -0.1572940 |
| CASD1 | -0.1573344 |
| GATA5 | -0.1573418 |
| GHDC | -0.1573701 |
| ITPR2 | -0.1574310 |
| CCDC173 | -0.1574447 |
| ZNF236 | -0.1575086 |
| NDUFA2 | -0.1575248 |
| TSHZ1 | -0.1575527 |
| CLHC1 | -0.1576198 |
| PALM3 | -0.1577173 |
| IQCE | -0.1577643 |
| SPRYD3 | -0.1578300 |
| KIAA0040 | -0.1578685 |
| ZNF528 | -0.1579136 |
| OMD | -0.1579167 |
| LARGE | -0.1579785 |
| BAI1 | -0.1581447 |
| ITGB3 | -0.1581777 |
| PCYOX1 | -0.1582029 |
| FAM69B | -0.1582035 |
| MOCS2 | -0.1582225 |
| TBCA | -0.1582278 |
| FRY | -0.1584048 |
| MYEF2 | -0.1584273 |
| GLI4 | -0.1584950 |
| NUMA1 | -0.1585471 |
| TMEM141 | -0.1585735 |
| MYBPH | -0.1586327 |
| RHOBTB2 | -0.1587866 |
| PKN3 | -0.1587893 |
| EMX1 | -0.1588247 |
| SDR39U1 | -0.1588731 |
| PDE6B | -0.1591085 |
| SNX21 | -0.1591254 |
| GP1BB | -0.1591631 |
| PIANP | -0.1591977 |
| ZNF563 | -0.1592527 |
| HLCS | -0.1593046 |
| GATM | -0.1593341 |
| IL20RA | -0.1593537 |
| PPFIA1 | -0.1593621 |
| CDO1 | -0.1594110 |
| GTF2I | -0.1594535 |
| NPIPB9 | -0.1595247 |
| DSEL | -0.1596115 |
| SOX12 | -0.1596660 |
| ACOT1 | -0.1596884 |
| DIS3L | -0.1597112 |
| LEF1 | -0.1597656 |
| MRPS35 | -0.1597961 |
| SYT7 | -0.1598834 |
| ST6GALNAC2 | -0.1599571 |
| IDUA | -0.1600156 |
| SHISA2 | -0.1600206 |
| PRSS50 | -0.1600437 |
| SHF | -0.1601003 |
| SFRP2 | -0.1602254 |
| TMEM41B | -0.1602269 |
| C11orf58 | -0.1602721 |
| DNAJC17 | -0.1604395 |
| GAS8 | -0.1605996 |
| C16orf13 | -0.1606610 |
| COMMD10 | -0.1606847 |
| TMEM132C | -0.1606941 |
| CBR4 | -0.1607284 |
| STXBP3 | -0.1608295 |
| DNAJA4 | -0.1608441 |
| OTUD7B | -0.1608749 |
| HSPB7 | -0.1608988 |
| CAB39L | -0.1609597 |
| ZNF44 | -0.1609639 |
| ANKRD29 | -0.1610100 |
| GNPDA2 | -0.1611998 |
| YEATS4 | -0.1613191 |
| ITFG3 | -0.1613572 |
| RAB22A | -0.1614970 |
| EPHA10 | -0.1615551 |
| OVGP1 | -0.1615589 |
| RNF103 | -0.1617133 |
| KBTBD3 | -0.1617830 |
| GREM2 | -0.1618137 |
| DNASE1L2 | -0.1618182 |
| PAAF1 | -0.1618945 |
| ADCY6 | -0.1621023 |
| TMEM67 | -0.1621184 |
| CCDC25 | -0.1621455 |
| PLEKHN1 | -0.1621667 |
| EEF2K | -0.1621686 |
| RALGPS1 | -0.1622019 |
| LIFR | -0.1622236 |
| PPP1R36 | -0.1623200 |
| FAM84B | -0.1623307 |
| POLR2L | -0.1624262 |
| CNOT8 | -0.1624358 |
| EDIL3 | -0.1624618 |
| FZD6 | -0.1624648 |
| AATK | -0.1625356 |
| C12orf10 | -0.1626048 |
| FLYWCH2 | -0.1626094 |
| PLEKHA5 | -0.1626304 |
| APPL2 | -0.1627322 |
| WASL | -0.1628186 |
| TRAPPC13 | -0.1628507 |
| DSCAML1 | -0.1630178 |
| CKMT2 | -0.1631204 |
| PIGH | -0.1633442 |
| TIMP3 | -0.1633503 |
| WFS1 | -0.1633750 |
| ZNF12 | -0.1638774 |
| ARHGEF10 | -0.1639167 |
| MIB1 | -0.1639362 |
| COASY | -0.1639994 |
| ABCA5 | -0.1640029 |
| KIAA1279 | -0.1640072 |
| CC2D2A | -0.1640170 |
| KANK2 | -0.1640183 |
| LYRM1 | -0.1640755 |
| GPATCH2 | -0.1641203 |
| ALDH6A1 | -0.1641360 |
| ABLIM2 | -0.1643036 |
| MBLAC2 | -0.1643079 |
| C12orf76 | -0.1644006 |
| PIGB | -0.1644751 |
| HAGHL | -0.1645302 |
| CAV1 | -0.1645466 |
| CCNB3 | -0.1645870 |
| EVA1B | -0.1646729 |
| USP47 | -0.1646768 |
| MGMT | -0.1647545 |
| KLHL41 | -0.1647886 |
| CIB3 | -0.1648258 |
| C14orf79 | -0.1650026 |
| NTF4 | -0.1650356 |
| CNNM3 | -0.1650521 |
| SCIN | -0.1650743 |
| CHID1 | -0.1650812 |
| MPP3 | -0.1651272 |
| GPR143 | -0.1651798 |
| CCDC126 | -0.1652252 |
| ZBTB41 | -0.1653221 |
| C11orf96 | -0.1655004 |
| SDPR | -0.1655527 |
| IFT81 | -0.1655963 |
| ARHGAP39 | -0.1656580 |
| PNMAL1 | -0.1657145 |
| PCF11 | -0.1657280 |
| C12orf66 | -0.1659245 |
| HIST3H2A | -0.1660088 |
| KRT1 | -0.1660933 |
| RHOT2 | -0.1661250 |
| CYP2A13 | -0.1663217 |
| ZNF251 | -0.1663300 |
| ALDH7A1 | -0.1664961 |
| F2RL1 | -0.1665568 |
| LRRC14 | -0.1665840 |
| PEBP4 | -0.1666021 |
| CCDC148 | -0.1666625 |
| HIGD1A | -0.1666841 |
| SUOX | -0.1666997 |
| SPATA7 | -0.1667204 |
| NTHL1 | -0.1668335 |
| CBFA2T3 | -0.1668411 |
| HSPA12B | -0.1668692 |
| SPTSSB | -0.1669062 |
| RPRD1A | -0.1670056 |
| RFX7 | -0.1670588 |
| PDCD6IP | -0.1670995 |
| FITM2 | -0.1671109 |
| PTGES | -0.1671735 |
| ACADS | -0.1671924 |
| CYB5D2 | -0.1672806 |
| MAGI1 | -0.1673115 |
| ADRA1B | -0.1673318 |
| NALCN | -0.1673872 |
| MEIS3 | -0.1677313 |
| NTN4 | -0.1677608 |
| MYOM2 | -0.1677704 |
| TGFB3 | -0.1677728 |
| MYZAP | -0.1678552 |
| NAP1L5 | -0.1678616 |
| SETBP1 | -0.1678710 |
| TTC37 | -0.1679017 |
| NDUFB10 | -0.1679925 |
| SFTPD | -0.1680427 |
| NT5C | -0.1680680 |
| PTPRB | -0.1681128 |
| LMTK3 | -0.1681960 |
| BLVRB | -0.1682243 |
| C1orf53 | -0.1682301 |
| CSNK1G3 | -0.1682499 |
| KAT2A | -0.1682600 |
| RNF43 | -0.1683500 |
| RBP4 | -0.1683795 |
| GSC | -0.1684055 |
| STAT6 | -0.1684093 |
| FKBP4 | -0.1684574 |
| COG1 | -0.1684586 |
| TMEM87A | -0.1684594 |
| LRRC32 | -0.1684790 |
| PREPL | -0.1685159 |
| BAZ2B | -0.1685777 |
| CDK20 | -0.1687131 |
| L3MBTL1 | -0.1688161 |
| MTA3 | -0.1688217 |
| PPIP5K1 | -0.1688561 |
| PYGL | -0.1689594 |
| TRNP1 | -0.1691348 |
| ARMCX4 | -0.1691353 |
| SLC35E2 | -0.1691808 |
| JAKMIP3 | -0.1692043 |
| AHCYL2 | -0.1693222 |
| INTU | -0.1695368 |
| STEAP4 | -0.1695429 |
| SPATA6 | -0.1695677 |
| BAG4 | -0.1698228 |
| NHLRC4 | -0.1698275 |
| GPM6A | -0.1699679 |
| SLC35A3 | -0.1700233 |
| CTDSPL | -0.1700833 |
| USP7 | -0.1700919 |
| PPP1R1C | -0.1700978 |
| BCAR3 | -0.1701010 |
| CIDEA | -0.1702995 |
| EIF3J | -0.1703522 |
| PCSK1 | -0.1703615 |
| DST | -0.1703700 |
| GALNT15 | -0.1705777 |
| RASSF7 | -0.1705847 |
| HECTD2 | -0.1706166 |
| GRTP1 | -0.1706843 |
| LCN12 | -0.1707127 |
| RTF1 | -0.1707158 |
| ZNF740 | -0.1707495 |
| REM2 | -0.1708484 |
| PJA2 | -0.1710661 |
| SUMF1 | -0.1710819 |
| ZNF404 | -0.1711096 |
| LRRC2 | -0.1711151 |
| C16orf72 | -0.1713053 |
| PLCXD3 | -0.1713835 |
| ZNF444 | -0.1714454 |
| ZNF25 | -0.1715068 |
| TMEM129 | -0.1715260 |
| SPAG6 | -0.1715684 |
| TYSND1 | -0.1717011 |
| RHOD | -0.1717780 |
| ADIPOR2 | -0.1718213 |
| SPEN | -0.1718252 |
| ICA1 | -0.1718710 |
| SSPN | -0.1719495 |
| CNTD1 | -0.1720239 |
| PEX12 | -0.1720498 |
| PLA2G16 | -0.1720549 |
| DYRK3 | -0.1721647 |
| CORO6 | -0.1721909 |
| LEP | -0.1722842 |
| FGF18 | -0.1724990 |
| GPR124 | -0.1725277 |
| IL13RA2 | -0.1726638 |
| HSD11B2 | -0.1726639 |
| LRRC36 | -0.1727060 |
| BBS10 | -0.1727594 |
| FCGRT | -0.1727707 |
| TMEM99 | -0.1728098 |
| CHMP2A | -0.1728810 |
| FKBP1B | -0.1730326 |
| NFATC4 | -0.1730400 |
| DYNLT3 | -0.1730921 |
| SMIM19 | -0.1731371 |
| NAP1L3 | -0.1732127 |
| PYROXD2 | -0.1732440 |
| PIGX | -0.1733181 |
| HYPK | -0.1733249 |
| NCAM2 | -0.1733835 |
| LYRM5 | -0.1734339 |
| TMEM64 | -0.1734485 |
| PRR4 | -0.1734761 |
| DZANK1 | -0.1734990 |
| TOMM7 | -0.1735123 |
| COL14A1 | -0.1735244 |
| GKAP1 | -0.1735815 |
| ZNF776 | -0.1737619 |
| MSRB3 | -0.1737956 |
| SULT1A4 | -0.1739465 |
| ACVR2B | -0.1739671 |
| E4F1 | -0.1739872 |
| PPDPF | -0.1740344 |
| SYNE4 | -0.1741744 |
| RAB3A | -0.1742364 |
| AKAP9 | -0.1742380 |
| DALRD3 | -0.1743694 |
| RFX2 | -0.1743799 |
| TSNAXIP1 | -0.1743960 |
| GRK4 | -0.1745189 |
| ST6GAL2 | -0.1745809 |
| AP3M2 | -0.1746885 |
| TTBK2 | -0.1747068 |
| C9orf117 | -0.1747528 |
| S100G | -0.1747961 |
| BTRC | -0.1748280 |
| MAN2A2 | -0.1750000 |
| CSMD3 | -0.1750976 |
| PLEKHB1 | -0.1753585 |
| GET4 | -0.1754478 |
| WHSC1L1 | -0.1755747 |
| C19orf80 | -0.1755914 |
| SNX1 | -0.1756262 |
| MXD4 | -0.1757674 |
| ENPP4 | -0.1757994 |
| ZMAT2 | -0.1758312 |
| PYCRL | -0.1758315 |
| CITED4 | -0.1758353 |
| KIAA1109 | -0.1758481 |
| CDKN1B | -0.1758526 |
| ARMC9 | -0.1759790 |
| ZFP14 | -0.1760296 |
| NAV3 | -0.1760557 |
| ALG10B | -0.1761077 |
| PRKAA2 | -0.1762048 |
| ZBTB47 | -0.1763069 |
| CDAN1 | -0.1763144 |
| ATRIP | -0.1764267 |
| NMNAT2 | -0.1765632 |
| UBXN10 | -0.1765750 |
| GDE1 | -0.1767356 |
| RAB38 | -0.1767597 |
| EIF4B | -0.1767623 |
| PDE2A | -0.1768363 |
| FUT8 | -0.1768389 |
| ZNF441 | -0.1768405 |
| PEX11A | -0.1769052 |
| ATP8B3 | -0.1769337 |
| NCOR2 | -0.1769637 |
| ZNF135 | -0.1770349 |
| PCYOX1L | -0.1770715 |
| UTP15 | -0.1770826 |
| GCOM1 | -0.1771436 |
| MEIS2 | -0.1774751 |
| FABP4 | -0.1775591 |
| LRTM2 | -0.1776226 |
| ARHGAP6 | -0.1778034 |
| ZNF304 | -0.1778216 |
| MAGI3 | -0.1778580 |
| TELO2 | -0.1779150 |
| FAM13B | -0.1781775 |
| ZFP41 | -0.1781849 |
| PPP1R3F | -0.1782217 |
| PDDC1 | -0.1782576 |
| CLK4 | -0.1783625 |
| GOLT1A | -0.1784420 |
| CA14 | -0.1785791 |
| EARS2 | -0.1786165 |
| OSBPL7 | -0.1786324 |
| MFAP1 | -0.1787751 |
| SLC7A4 | -0.1788987 |
| RHBDF1 | -0.1790839 |
| CLEC3A | -0.1790845 |
| RIBC1 | -0.1793407 |
| ZMAT4 | -0.1794622 |
| NLRP12 | -0.1795288 |
| IGSF1 | -0.1795684 |
| CCDC91 | -0.1796239 |
| TRIQK | -0.1798293 |
| LHFP | -0.1798300 |
| PDGFRB | -0.1799206 |
| WDFY3 | -0.1800529 |
| PLEKHF2 | -0.1800664 |
| CYP21A2 | -0.1800670 |
| CLEC11A | -0.1804388 |
| AXIN2 | -0.1805842 |
| CNN1 | -0.1806976 |
| UBE2B | -0.1810281 |
| PDGFA | -0.1811454 |
| KIF9 | -0.1812423 |
| NSMCE1 | -0.1815317 |
| SLIT2 | -0.1815320 |
| WDR60 | -0.1815953 |
| MCCC2 | -0.1816786 |
| JAG1 | -0.1819324 |
| HTT | -0.1819681 |
| PPM1H | -0.1820803 |
| NPEPL1 | -0.1820901 |
| C16orf74 | -0.1821144 |
| MAPK8IP2 | -0.1821544 |
| ZNF688 | -0.1822226 |
| SCN2B | -0.1823399 |
| POMT2 | -0.1824226 |
| NACAD | -0.1824248 |
| TEKT4 | -0.1824829 |
| ZCCHC24 | -0.1825969 |
| AKAP12 | -0.1825998 |
| FAM63B | -0.1827478 |
| POLR3K | -0.1828323 |
| WDR54 | -0.1828373 |
| MRFAP1 | -0.1828735 |
| LY6H | -0.1828944 |
| SLC25A21-AS1 | -0.1831425 |
| TNNT3 | -0.1832065 |
| C2CD5 | -0.1832449 |
| TMEM101 | -0.1835303 |
| HSD17B1 | -0.1835319 |
| CROT | -0.1840129 |
| FMN1 | -0.1840864 |
| RUNDC3A | -0.1841317 |
| EML2 | -0.1842056 |
| WNT2B | -0.1843116 |
| CST5 | -0.1844033 |
| MAP3K12 | -0.1845170 |
| RCOR3 | -0.1845466 |
| NNAT | -0.1845796 |
| ZNF577 | -0.1846896 |
| ASB13 | -0.1847763 |
| LEAP2 | -0.1847948 |
| PLXNB1 | -0.1848270 |
| ZNF415 | -0.1849804 |
| EMCN | -0.1850065 |
| SLC4A7 | -0.1850284 |
| POLK | -0.1851294 |
| ITGA7 | -0.1851597 |
| CAPN8 | -0.1852025 |
| CYP4F11 | -0.1852585 |
| FOXD2 | -0.1852781 |
| TM2D1 | -0.1853360 |
| ITGA3 | -0.1854031 |
| PTK2 | -0.1854461 |
| ACSL3 | -0.1855361 |
| TMEM26 | -0.1855813 |
| DDAH1 | -0.1856799 |
| ANKAR | -0.1856897 |
| LMCD1 | -0.1857566 |
| PAX2 | -0.1857912 |
| TTC21A | -0.1858427 |
| MAGEB6 | -0.1858536 |
| FBXL2 | -0.1858654 |
| ENPP1 | -0.1860190 |
| ZFYVE19 | -0.1861167 |
| LIAS | -0.1862110 |
| GSTT1 | -0.1863460 |
| C11orf70 | -0.1864006 |
| DYNC2H1 | -0.1864125 |
| EHD2 | -0.1864177 |
| ARHGEF40 | -0.1864425 |
| MAPKBP1 | -0.1864732 |
| ZNF433 | -0.1864821 |
| SLC35E3 | -0.1864889 |
| ECM1 | -0.1867398 |
| ZNF620 | -0.1869269 |
| ZNF396 | -0.1870344 |
| WDR83 | -0.1870413 |
| CYBRD1 | -0.1871135 |
| RBM12 | -0.1871775 |
| KCNIP3 | -0.1872018 |
| TMBIM4 | -0.1874873 |
| SYT17 | -0.1875695 |
| NAGS | -0.1876973 |
| VCX | -0.1876998 |
| BRICD5 | -0.1877316 |
| TOM1L1 | -0.1877426 |
| MUC20 | -0.1879743 |
| C5orf45 | -0.1881847 |
| HGD | -0.1882706 |
| NUBPL | -0.1883015 |
| ZADH2 | -0.1888864 |
| LRP6 | -0.1889207 |
| SPAG17 | -0.1890145 |
| HMGCL | -0.1891027 |
| NTRK2 | -0.1893189 |
| CERS2 | -0.1893266 |
| HTR1F | -0.1893802 |
| TRMT10A | -0.1894070 |
| C12orf57 | -0.1894735 |
| NDUFC2 | -0.1894910 |
| TBX2 | -0.1895507 |
| TPRN | -0.1895877 |
| LRIG1 | -0.1896196 |
| DIO1 | -0.1896648 |
| PTPN13 | -0.1897678 |
| SPG11 | -0.1898585 |
| FAHD1 | -0.1898813 |
| ARL1 | -0.1900642 |
| AIG1 | -0.1901106 |
| BCAT2 | -0.1902423 |
| YPEL3 | -0.1903505 |
| DTX3 | -0.1903808 |
| ZMYND12 | -0.1904944 |
| LIPE | -0.1905165 |
| C19orf18 | -0.1905532 |
| GLCE | -0.1905917 |
| MEAF6 | -0.1906862 |
| MPC2 | -0.1907044 |
| SEPT12 | -0.1907471 |
| WDR78 | -0.1909737 |
| CCDC30 | -0.1909917 |
| DENND1B | -0.1910233 |
| NDUFAF1 | -0.1911313 |
| UBAP1L | -0.1911351 |
| IGFBP2 | -0.1911977 |
| PLA2G12A | -0.1912468 |
| SERGEF | -0.1912979 |
| YTHDC2 | -0.1914251 |
| APBB3 | -0.1914745 |
| FCER1A | -0.1914845 |
| ULK2 | -0.1914862 |
| HHEX | -0.1914876 |
| HOXC6 | -0.1915339 |
| MYOF | -0.1916402 |
| ERICH2 | -0.1917743 |
| METTL15 | -0.1917926 |
| CBLN4 | -0.1918115 |
| SLC26A10 | -0.1918492 |
| VEZF1 | -0.1918686 |
| TAPT1 | -0.1919867 |
| SIAH2 | -0.1919885 |
| GALNT4 | -0.1921659 |
| CHD1 | -0.1922128 |
| CRISPLD1 | -0.1922409 |
| MORN4 | -0.1923931 |
| SLC22A15 | -0.1924097 |
| SYNC | -0.1925250 |
| CRYZ | -0.1929168 |
| SNX13 | -0.1931475 |
| SMARCA1 | -0.1931843 |
| SYT4 | -0.1932375 |
| KAL1 | -0.1933473 |
| CETN3 | -0.1935376 |
| SLC22A4 | -0.1935627 |
| FGFR1 | -0.1937800 |
| SFXN2 | -0.1937946 |
| ATG4D | -0.1938289 |
| HSD17B4 | -0.1938571 |
| ROPN1L | -0.1938579 |
| MPP7 | -0.1941977 |
| C12orf29 | -0.1943708 |
| PBX1 | -0.1944943 |
| DMTN | -0.1945824 |
| CCDC125 | -0.1946105 |
| OXTR | -0.1947667 |
| ADAL | -0.1947799 |
| DCHS1 | -0.1948967 |
| ZNF629 | -0.1949343 |
| TMEM161B | -0.1949368 |
| GLRA3 | -0.1949847 |
| ZFP2 | -0.1951544 |
| RAB40C | -0.1952391 |
| CST3 | -0.1953332 |
| DMXL1 | -0.1953624 |
| FAM229B | -0.1953887 |
| BEST4 | -0.1953974 |
| IL17RB | -0.1955007 |
| PIP5KL1 | -0.1956438 |
| SPATA17 | -0.1957517 |
| ZNF853 | -0.1960108 |
| TIMM13 | -0.1964142 |
| CDHR3 | -0.1964893 |
| SPEF2 | -0.1966342 |
| DPY19L4 | -0.1966694 |
| FAM73A | -0.1967525 |
| UVSSA | -0.1967657 |
| DLG5 | -0.1969101 |
| PABPC1L | -0.1970236 |
| GARNL3 | -0.1971371 |
| GPR98 | -0.1972305 |
| MFSD7 | -0.1973650 |
| GSTM5 | -0.1974282 |
| GLDN | -0.1978480 |
| EPS8L2 | -0.1979730 |
| SPEF1 | -0.1980164 |
| WDR24 | -0.1980782 |
| PHF21B | -0.1980859 |
| HIST1H2AB | -0.1980887 |
| DBT | -0.1981161 |
| ZCCHC10 | -0.1981356 |
| RND2 | -0.1982144 |
| ZNF446 | -0.1982799 |
| KCND2 | -0.1983286 |
| SPATA20 | -0.1983654 |
| HOXD8 | -0.1983954 |
| CACNG4 | -0.1984962 |
| C1orf27 | -0.1985767 |
| BDP1 | -0.1986598 |
| ZNF75A | -0.1987094 |
| NANOG | -0.1987489 |
| CCDC11 | -0.1987768 |
| ELOVL5 | -0.1989124 |
| C9orf24 | -0.1990050 |
| TNNC2 | -0.1990515 |
| TRAF3IP1 | -0.1994201 |
| TRAK2 | -0.1996089 |
| AP2B1 | -0.1996106 |
| TBC1D19 | -0.1996512 |
| AMDHD1 | -0.1996581 |
| RORC | -0.1997503 |
| TCEB2 | -0.1997958 |
| BHLHE40 | -0.1997972 |
| PPIP5K2 | -0.2000804 |
| SMAD3 | -0.2000961 |
| GRIN2C | -0.2000987 |
| KRR1 | -0.2001560 |
| PHLDA1 | -0.2003019 |
| PEX11G | -0.2005341 |
| RBP7 | -0.2007121 |
| POSTN | -0.2008208 |
| ARC | -0.2010782 |
| AP1AR | -0.2012897 |
| CYSTM1 | -0.2013150 |
| KCNC1 | -0.2016907 |
| RASA4 | -0.2017163 |
| GPRASP1 | -0.2019756 |
| FGD3 | -0.2020405 |
| GLIPR1L2 | -0.2021129 |
| MKX | -0.2023438 |
| NOV | -0.2023998 |
| MPP2 | -0.2024565 |
| CCDC153 | -0.2025635 |
| PRR15L | -0.2026002 |
| MAPK8IP3 | -0.2028191 |
| EPS15L1 | -0.2034038 |
| ZFHX4 | -0.2034695 |
| CCP110 | -0.2035724 |
| C15orf65 | -0.2036379 |
| SGCD | -0.2038254 |
| ATG16L2 | -0.2039588 |
| PLSCR4 | -0.2039988 |
| COMP | -0.2041098 |
| PDCD4 | -0.2041679 |
| SNCG | -0.2043285 |
| GPT | -0.2044415 |
| HTRA1 | -0.2045399 |
| EPHX4 | -0.2046196 |
| VCX3A | -0.2046803 |
| TMEM238 | -0.2047341 |
| PRKCE | -0.2047508 |
| SPATA4 | -0.2048318 |
| NME4 | -0.2049038 |
| CDS1 | -0.2049886 |
| MYO6 | -0.2050144 |
| GTF2IRD2 | -0.2050609 |
| LPIN3 | -0.2052688 |
| GIN1 | -0.2053736 |
| LRRN2 | -0.2054466 |
| POMGNT1 | -0.2058205 |
| ZNF83 | -0.2058482 |
| FBXL7 | -0.2060686 |
| PAQR5 | -0.2061034 |
| CHRD | -0.2061226 |
| SEMA3G | -0.2061307 |
| SYDE2 | -0.2061966 |
| GPR26 | -0.2062756 |
| LANCL1 | -0.2063610 |
| LAMA2 | -0.2064922 |
| PMAIP1 | -0.2065126 |
| FBXO36 | -0.2065690 |
| NR4A2 | -0.2066410 |
| A1BG | -0.2068575 |
| ZNF177 | -0.2069633 |
| KATNAL2 | -0.2070926 |
| ZNF425 | -0.2071885 |
| MYO15B | -0.2072869 |
| FOXS1 | -0.2073075 |
| RELL1 | -0.2077550 |
| TRPC1 | -0.2077997 |
| SLC4A8 | -0.2079419 |
| ZNF14 | -0.2081261 |
| GATA2 | -0.2082079 |
| ZNRF3 | -0.2084769 |
| NISCH | -0.2085010 |
| LAMA3 | -0.2085496 |
| DCTN4 | -0.2087822 |
| NQO1 | -0.2089183 |
| NPAS1 | -0.2089392 |
| MARVELD2 | -0.2089396 |
| SLTM | -0.2092485 |
| SORCS1 | -0.2093238 |
| FAM216A | -0.2097171 |
| C1orf21 | -0.2097843 |
| ZNF500 | -0.2100335 |
| ISOC1 | -0.2100684 |
| SOWAHA | -0.2102659 |
| ARMCX1 | -0.2104022 |
| ADORA1 | -0.2104058 |
| CERS6 | -0.2105668 |
| ASH2L | -0.2106276 |
| MICALL2 | -0.2106683 |
| RPH3AL | -0.2107428 |
| OCLN | -0.2109500 |
| INSR | -0.2111902 |
| SULF2 | -0.2112602 |
| SESTD1 | -0.2112817 |
| STMN3 | -0.2113097 |
| RIPPLY3 | -0.2113201 |
| HS6ST3 | -0.2113399 |
| TRIM66 | -0.2117478 |
| FXYD3 | -0.2117548 |
| IMPACT | -0.2117673 |
| PLIN1 | -0.2118032 |
| CHCHD5 | -0.2118438 |
| SPANXA1 | -0.2120474 |
| MTERFD3 | -0.2121611 |
| ABHD17C | -0.2121674 |
| SSFA2 | -0.2122309 |
| CCNO | -0.2123576 |
| HSPA12A | -0.2125047 |
| AQP11 | -0.2125142 |
| PURA | -0.2125406 |
| NTS | -0.2125776 |
| FAM102A | -0.2126623 |
| ZKSCAN2 | -0.2126758 |
| CAMLG | -0.2127569 |
| CPEB3 | -0.2127589 |
| HID1 | -0.2127778 |
| ISYNA1 | -0.2127794 |
| INADL | -0.2132526 |
| PLP1 | -0.2133182 |
| C11orf49 | -0.2133851 |
| HAGH | -0.2134498 |
| TMEM106B | -0.2135404 |
| ARFGEF1 | -0.2135802 |
| DAK | -0.2137068 |
| ZNF580 | -0.2137306 |
| GSTT2 | -0.2139763 |
| C9orf89 | -0.2140232 |
| VPS37D | -0.2141454 |
| RAD50 | -0.2141575 |
| EPB41L1 | -0.2142585 |
| IFT122 | -0.2143450 |
| BNIPL | -0.2143797 |
| BAG1 | -0.2145402 |
| FBXL5 | -0.2145852 |
| ZMAT1 | -0.2147441 |
| FGFR2 | -0.2147467 |
| CACNA1D | -0.2148654 |
| MAATS1 | -0.2150130 |
| IFT88 | -0.2150761 |
| BBS4 | -0.2154590 |
| MRFAP1L1 | -0.2155062 |
| DNAH5 | -0.2155303 |
| PTDSS2 | -0.2157912 |
| FAM81B | -0.2158769 |
| KLHDC1 | -0.2158805 |
| NRCAM | -0.2161305 |
| GPRASP2 | -0.2161965 |
| MNS1 | -0.2163653 |
| ENHO | -0.2163789 |
| GEM | -0.2165226 |
| TTC39A | -0.2166039 |
| C1orf168 | -0.2168538 |
| HOOK1 | -0.2168819 |
| SLC22A18 | -0.2170363 |
| MAGI2 | -0.2170594 |
| BMPER | -0.2173980 |
| CYP4F22 | -0.2175505 |
| CHST15 | -0.2175722 |
| MAP6 | -0.2176348 |
| KRTCAP3 | -0.2179221 |
| SREK1 | -0.2179523 |
| KRT222 | -0.2181619 |
| SAP18 | -0.2181687 |
| PRSS1 | -0.2183096 |
| FOXJ1 | -0.2189629 |
| ZNF516 | -0.2194297 |
| JMJD8 | -0.2194793 |
| CNNM4 | -0.2195198 |
| FAM57B | -0.2195381 |
| ANKRA2 | -0.2196767 |
| BRCA1 | -0.2196840 |
| STH | -0.2198085 |
| POLI | -0.2200227 |
| MZT2B | -0.2201502 |
| TMEM181 | -0.2202311 |
| PTGR2 | -0.2203075 |
| PLAC9 | -0.2203703 |
| LCA5 | -0.2204237 |
| ANKHD1-EIF4EBP3 | -0.2205899 |
| MICALCL | -0.2208554 |
| CREBBP | -0.2209666 |
| ZNF112 | -0.2210857 |
| C2orf81 | -0.2211183 |
| C5orf24 | -0.2217358 |
| UACA | -0.2218146 |
| GLS2 | -0.2218944 |
| CMBL | -0.2220596 |
| RERGL | -0.2222838 |
| HEPACAM2 | -0.2223044 |
| AHSA2 | -0.2224099 |
| TMEM9B | -0.2224993 |
| SATB2 | -0.2227203 |
| LCA5L | -0.2227367 |
| PIGT | -0.2227784 |
| ASIC1 | -0.2228464 |
| SULT1A1 | -0.2229149 |
| FHOD3 | -0.2231853 |
| SNX24 | -0.2231963 |
| MMP16 | -0.2233679 |
| CGB1 | -0.2234373 |
| SLC25A35 | -0.2237847 |
| SSBP2 | -0.2241171 |
| CIRBP | -0.2242209 |
| PTPLAD1 | -0.2242285 |
| ZNF814 | -0.2242498 |
| ZNF239 | -0.2243912 |
| FAN1 | -0.2243959 |
| CYHR1 | -0.2245036 |
| NAPRT1 | -0.2245406 |
| SAG | -0.2248969 |
| CATSPER2 | -0.2252455 |
| IL17D | -0.2255304 |
| ZNF214 | -0.2259693 |
| CHGA | -0.2261126 |
| GSTM1 | -0.2261794 |
| NDUFA7 | -0.2262698 |
| PRRG2 | -0.2262849 |
| FAAH2 | -0.2266548 |
| FAM183B | -0.2269426 |
| SLC16A6 | -0.2269657 |
| PTPRN2 | -0.2271111 |
| PCM1 | -0.2271667 |
| ARSG | -0.2272828 |
| AOC3 | -0.2273902 |
| CLUAP1 | -0.2274189 |
| EBF4 | -0.2274192 |
| GATAD1 | -0.2275507 |
| FZD8 | -0.2277224 |
| RUNDC1 | -0.2277609 |
| SHROOM3 | -0.2279069 |
| RHOB | -0.2280368 |
| PROSC | -0.2282917 |
| SCAMP1 | -0.2283476 |
| SLC51B | -0.2285420 |
| SERF1A | -0.2286405 |
| ARL3 | -0.2287852 |
| ARMCX2 | -0.2289038 |
| CD36 | -0.2290864 |
| TPPP | -0.2291362 |
| SNAPC2 | -0.2291943 |
| GPRC5C | -0.2292842 |
| SETD9 | -0.2297742 |
| CDKN2AIPNL | -0.2298344 |
| CCDC96 | -0.2299439 |
| CAPSL | -0.2300408 |
| SHROOM1 | -0.2300656 |
| SEC14L2 | -0.2301707 |
| GLOD5 | -0.2304512 |
| F7 | -0.2307126 |
| PHOSPHO2 | -0.2309178 |
| PI15 | -0.2309729 |
| KIF16B | -0.2310531 |
| DDHD2 | -0.2312349 |
| IQCK | -0.2313549 |
| DGAT1 | -0.2314263 |
| JMJD7 | -0.2315154 |
| NUDT16L1 | -0.2316552 |
| TMEM106C | -0.2317908 |
| ACKR3 | -0.2318677 |
| WBSCR27 | -0.2320057 |
| LRRC48 | -0.2322373 |
| HSPA1A | -0.2323496 |
| ALCAM | -0.2324122 |
| CHDH | -0.2324323 |
| LRBA | -0.2324907 |
| MGP | -0.2328154 |
| FAM173A | -0.2328332 |
| ANKS3 | -0.2335467 |
| SNAP25 | -0.2335471 |
| ARHGEF17 | -0.2336305 |
| CCDC176 | -0.2336501 |
| UGDH | -0.2336521 |
| SULT2B1 | -0.2337335 |
| ARHGAP36 | -0.2338608 |
| CITED1 | -0.2339194 |
| BCAS4 | -0.2339473 |
| ALB | -0.2341657 |
| PTP4A2 | -0.2341972 |
| EID1 | -0.2342548 |
| EGR3 | -0.2342601 |
| DNAH7 | -0.2343316 |
| WNT4 | -0.2343445 |
| C5 | -0.2345492 |
| NUCB2 | -0.2345619 |
| SYCP2 | -0.2347024 |
| RNASE4 | -0.2350076 |
| FAAH | -0.2351453 |
| EGFL8 | -0.2353134 |
| FAM179B | -0.2353282 |
| TMEM55A | -0.2356101 |
| N6AMT1 | -0.2356612 |
| DISP1 | -0.2357616 |
| VSTM2A | -0.2357853 |
| FSTL3 | -0.2361027 |
| DNMBP | -0.2361888 |
| KIAA1244 | -0.2363163 |
| AMPH | -0.2363551 |
| AHNAK | -0.2364239 |
| NFIA | -0.2365976 |
| CYB5R1 | -0.2366895 |
| NRAP | -0.2367181 |
| INPP4B | -0.2367562 |
| SRGAP1 | -0.2368585 |
| FAM83E | -0.2369752 |
| PLS1 | -0.2372853 |
| VPS28 | -0.2374596 |
| ACACB | -0.2379320 |
| KIAA1456 | -0.2381889 |
| GALNT6 | -0.2383534 |
| JMJD7-PLA2G4B | -0.2385457 |
| RBKS | -0.2385530 |
| SEZ6L | -0.2386945 |
| HOXC4 | -0.2387865 |
| FAM174B | -0.2387870 |
| KLHL42 | -0.2389239 |
| CRABP2 | -0.2390258 |
| CCDC85A | -0.2390930 |
| CCL14 | -0.2391681 |
| C2orf15 | -0.2395530 |
| B3GNT8 | -0.2397670 |
| CERS4 | -0.2399156 |
| SSH3 | -0.2401087 |
| LCMT2 | -0.2402235 |
| KRT19 | -0.2402509 |
| INPP5J | -0.2402581 |
| RIN1 | -0.2402720 |
| ZNF91 | -0.2404093 |
| PROM2 | -0.2404759 |
| SKP1 | -0.2406216 |
| DCAF16 | -0.2410241 |
| GPR160 | -0.2413509 |
| PPP6R1 | -0.2416948 |
| CLDN5 | -0.2417741 |
| C16orf89 | -0.2420837 |
| MKL2 | -0.2421298 |
| OLFM1 | -0.2422568 |
| SIRT3 | -0.2422968 |
| GDAP1 | -0.2424626 |
| KIAA1407 | -0.2424969 |
| ROGDI | -0.2425132 |
| KIAA1324L | -0.2425166 |
| SMIM1 | -0.2428938 |
| TMEM144 | -0.2430416 |
| CLU | -0.2433184 |
| STK36 | -0.2434515 |
| DISP2 | -0.2435041 |
| EFCC1 | -0.2435556 |
| DKFZP547L112 | -0.2438294 |
| ACSM1 | -0.2439243 |
| FUT1 | -0.2440200 |
| CDON | -0.2440879 |
| ZNF264 | -0.2444982 |
| PFKM | -0.2446242 |
| LRFN2 | -0.2450965 |
| NEBL | -0.2452300 |
| PLEKHH3 | -0.2453204 |
| NR0B1 | -0.2455140 |
| KLHL35 | -0.2455271 |
| ERBB3 | -0.2455374 |
| FBP1 | -0.2456815 |
| CPEB2 | -0.2457187 |
| ACOT4 | -0.2458026 |
| RADIL | -0.2458146 |
| LRRC46 | -0.2461496 |
| BZRAP1 | -0.2464211 |
| IGFBP4 | -0.2468842 |
| OCEL1 | -0.2468879 |
| CDKL3 | -0.2469761 |
| SIGIRR | -0.2470119 |
| FRS2 | -0.2473295 |
| SDC4 | -0.2473735 |
| GLI1 | -0.2474718 |
| HRASLS2 | -0.2474907 |
| ZNF219 | -0.2475652 |
| CASC4 | -0.2476968 |
| STOX1 | -0.2477551 |
| MAP9 | -0.2480277 |
| AKR7A3 | -0.2480895 |
| ROM1 | -0.2493001 |
| PREX1 | -0.2496343 |
| PRRT3 | -0.2499672 |
| TRAF5 | -0.2501538 |
| RBBP8 | -0.2501560 |
| WDR19 | -0.2504003 |
| KIFC2 | -0.2506738 |
| GXYLT2 | -0.2507146 |
| TCEAL6 | -0.2508564 |
| TRIM36 | -0.2508966 |
| MCCD1 | -0.2509394 |
| TPSD1 | -0.2512780 |
| HDAC11 | -0.2513427 |
| NPHP1 | -0.2514578 |
| ZSCAN18 | -0.2521437 |
| HCAR1 | -0.2525311 |
| KCTD3 | -0.2527434 |
| OSR2 | -0.2527594 |
| MDP1 | -0.2529167 |
| SPTBN5 | -0.2529935 |
| SMOC2 | -0.2531223 |
| FANK1 | -0.2532298 |
| PTGER3 | -0.2534859 |
| ENO2 | -0.2537826 |
| COL2A1 | -0.2539032 |
| LAMP5 | -0.2539914 |
| ZNF92 | -0.2544876 |
| TENC1 | -0.2551904 |
| AMZ1 | -0.2553027 |
| AGBL2 | -0.2553515 |
| BTF3 | -0.2555288 |
| WFIKKN1 | -0.2565184 |
| KIAA1257 | -0.2565380 |
| SLC24A3 | -0.2572287 |
| HEYL | -0.2574535 |
| RTN4RL1 | -0.2575056 |
| S100A13 | -0.2575632 |
| TMEM128 | -0.2576719 |
| PDGFD | -0.2578586 |
| TXNDC16 | -0.2580908 |
| HEXIM1 | -0.2581909 |
| TCEA2 | -0.2585226 |
| MYCBPAP | -0.2585442 |
| LTC4S | -0.2585964 |
| DNAAF3 | -0.2586082 |
| ABCC5 | -0.2586862 |
| GRAMD1C | -0.2587518 |
| FAM214A | -0.2587843 |
| PCMTD2 | -0.2587924 |
| LUZP2 | -0.2587997 |
| FAM110C | -0.2588157 |
| DACT3 | -0.2588303 |
| FMO5 | -0.2589245 |
| CHPT1 | -0.2589514 |
| TMEM25 | -0.2591025 |
| SPARCL1 | -0.2592528 |
| GPC1 | -0.2595604 |
| KIAA1377 | -0.2595918 |
| MICU3 | -0.2597314 |
| GREB1L | -0.2597717 |
| EPS8 | -0.2599910 |
| MYOZ3 | -0.2601400 |
| HDGFRP3 | -0.2602116 |
| DDIT4L | -0.2602710 |
| C1QTNF3 | -0.2604154 |
| CCDC104 | -0.2604357 |
| C16orf93 | -0.2606151 |
| CHADL | -0.2608340 |
| EFCAB2 | -0.2610007 |
| ADRA2C | -0.2610252 |
| DECR2 | -0.2610924 |
| SYNPO2L | -0.2611741 |
| TIMP4 | -0.2616484 |
| CCDC24 | -0.2616535 |
| IGIP | -0.2616599 |
| WDR35 | -0.2617890 |
| ABHD1 | -0.2623580 |
| CA2 | -0.2624801 |
| STK32B | -0.2625398 |
| MMP10 | -0.2626343 |
| PGLYRP2 | -0.2626630 |
| C17orf58 | -0.2628985 |
| RASL11B | -0.2629189 |
| TCEAL5 | -0.2630019 |
| TPPP3 | -0.2633777 |
| TCEAL3 | -0.2636813 |
| LRRC4C | -0.2636916 |
| NR2F2 | -0.2638068 |
| EVL | -0.2641256 |
| HEY1 | -0.2642447 |
| CARTPT | -0.2642779 |
| ECI1 | -0.2647962 |
| RABEP1 | -0.2652645 |
| ANKRD42 | -0.2654827 |
| CCDC64B | -0.2655526 |
| LEPREL4 | -0.2655916 |
| ATP7B | -0.2656308 |
| FAM169A | -0.2656347 |
| SSTR2 | -0.2661615 |
| ATP1A2 | -0.2663059 |
| SPOCK1 | -0.2664624 |
| LRP2 | -0.2671115 |
| ZDHHC11 | -0.2675523 |
| CCDC151 | -0.2676110 |
| ADAMTS18 | -0.2678695 |
| CCDC66 | -0.2679043 |
| NDP | -0.2680733 |
| TUBA3D | -0.2682174 |
| NT5M | -0.2683442 |
| NEIL1 | -0.2686063 |
| MFSD3 | -0.2686593 |
| FAXDC2 | -0.2687650 |
| THAP10 | -0.2688796 |
| MZF1 | -0.2691803 |
| ELMO3 | -0.2692121 |
| C17orf97 | -0.2692318 |
| PCSK6 | -0.2694005 |
| DCLK1 | -0.2694668 |
| HPGD | -0.2695101 |
| PHLDB3 | -0.2699532 |
| AMN1 | -0.2702875 |
| PHYHD1 | -0.2703462 |
| ETNK2 | -0.2704574 |
| CEP290 | -0.2706495 |
| AGT | -0.2706818 |
| FUZ | -0.2708856 |
| NELL1 | -0.2711896 |
| ATP8B1 | -0.2712571 |
| APBB2 | -0.2715084 |
| LRP1B | -0.2719024 |
| COL17A1 | -0.2720209 |
| PDK4 | -0.2720672 |
| SOCS2 | -0.2720971 |
| LZTFL1 | -0.2721924 |
| SYCE3 | -0.2728127 |
| GHR | -0.2730149 |
| KRT37 | -0.2730758 |
| SLC40A1 | -0.2732039 |
| BSN | -0.2735760 |
| SULT1A2 | -0.2736279 |
| GRIK3 | -0.2737729 |
| CX3CR1 | -0.2740373 |
| RHPN1 | -0.2741252 |
| ARNT2 | -0.2742368 |
| NUDT6 | -0.2745285 |
| ZC3H6 | -0.2750644 |
| LDLRAD4 | -0.2752527 |
| SLC9A3R1 | -0.2767679 |
| HCFC1R1 | -0.2767708 |
| MS4A8 | -0.2770513 |
| NEDD4L | -0.2771956 |
| FRZB | -0.2772323 |
| AARD | -0.2773953 |
| ZBTB16 | -0.2777248 |
| DYX1C1 | -0.2782264 |
| RIMKLA | -0.2783657 |
| GJA1 | -0.2785616 |
| PPP1R16A | -0.2791264 |
| ANKRD50 | -0.2793811 |
| C4orf32 | -0.2794570 |
| ABHD2 | -0.2796393 |
| RTN2 | -0.2797295 |
| CAPS2 | -0.2797771 |
| MYT1 | -0.2799908 |
| SYNPO2 | -0.2799944 |
| BRF2 | -0.2802276 |
| F2RL2 | -0.2805522 |
| SPANXD | -0.2806178 |
| ORAOV1 | -0.2806425 |
| KIAA0232 | -0.2807512 |
| COL4A6 | -0.2808589 |
| B4GALNT4 | -0.2808715 |
| PDE5A | -0.2808881 |
| SERP2 | -0.2809162 |
| SEMA3F | -0.2815620 |
| TFPI2 | -0.2819753 |
| BBS1 | -0.2820935 |
| ATHL1 | -0.2821335 |
| SPATA18 | -0.2824686 |
| RHOBTB3 | -0.2828694 |
| ATP6V1B1 | -0.2830906 |
| SRI | -0.2836405 |
| GRIA2 | -0.2837206 |
| C3orf52 | -0.2838404 |
| TCTN1 | -0.2842995 |
| GPD1L | -0.2850652 |
| GSTM3 | -0.2854745 |
| KIF3A | -0.2858500 |
| HIGD1B | -0.2860946 |
| RASEF | -0.2860991 |
| CCDC103 | -0.2865998 |
| COQ7 | -0.2867596 |
| ADRA2A | -0.2869655 |
| ASPHD1 | -0.2871286 |
| ASCL1 | -0.2872880 |
| REEP5 | -0.2873843 |
| HEXIM2 | -0.2877584 |
| ATP6AP1L | -0.2881265 |
| AMFR | -0.2882814 |
| MYO5C | -0.2883872 |
| PVALB | -0.2884867 |
| ZNF587 | -0.2886202 |
| ZNF552 | -0.2888965 |
| C20orf96 | -0.2895523 |
| MST1 | -0.2896675 |
| LYPD6 | -0.2902726 |
| KCNC2 | -0.2904126 |
| CELSR1 | -0.2904468 |
| PLIN4 | -0.2908580 |
| WNK4 | -0.2918747 |
| MPPED2 | -0.2921496 |
| HIST1H2AJ | -0.2930607 |
| MYL5 | -0.2930970 |
| FLNB | -0.2934683 |
| TRIM63 | -0.2947826 |
| UCN | -0.2949278 |
| CPE | -0.2952574 |
| C10orf32 | -0.2956925 |
| FGFR3 | -0.2957328 |
| CGN | -0.2971222 |
| C11orf52 | -0.2972026 |
| TPBG | -0.2974402 |
| C14orf132 | -0.2977493 |
| RAB17 | -0.2979723 |
| FAM155A | -0.2985280 |
| C15orf59 | -0.2986371 |
| PGAM2 | -0.2986633 |
| NEK10 | -0.2989310 |
| SORD | -0.2991808 |
| CYP2A6 | -0.2992712 |
| COL4A5 | -0.3005331 |
| EPHX2 | -0.3007485 |
| GNAZ | -0.3008495 |
| PRSS23 | -0.3013782 |
| CXXC4 | -0.3014512 |
| HIST1H2AK | -0.3022495 |
| STMN2 | -0.3025851 |
| CARD10 | -0.3025990 |
| EPB41L5 | -0.3026727 |
| TTC8 | -0.3027899 |
| RAB11FIP1 | -0.3031394 |
| AREG | -0.3038433 |
| CCDC106 | -0.3039462 |
| RGL3 | -0.3043974 |
| CSAD | -0.3048448 |
| SGK3 | -0.3050492 |
| PLEKHA6 | -0.3056189 |
| ECHDC2 | -0.3059640 |
| DOCK1 | -0.3066839 |
| IFT140 | -0.3069037 |
| TBX3 | -0.3074475 |
| H2AFJ | -0.3074522 |
| C6orf141 | -0.3076341 |
| SLC7A8 | -0.3077546 |
| CYP2A7 | -0.3080352 |
| MS4A2 | -0.3087270 |
| ACOX2 | -0.3092122 |
| GPR162 | -0.3095201 |
| C12orf60 | -0.3095478 |
| SLC16A5 | -0.3099765 |
| TRPS1 | -0.3109644 |
| TRIM45 | -0.3111484 |
| SHISA4 | -0.3115557 |
| HSPB8 | -0.3118456 |
| HPGDS | -0.3120186 |
| RAB26 | -0.3130001 |
| HSPA2 | -0.3139581 |
| CAMK2B | -0.3139973 |
| KRT79 | -0.3150995 |
| NOS1AP | -0.3158393 |
| AMIGO2 | -0.3159859 |
| NMNAT3 | -0.3162267 |
| CAMK2N1 | -0.3172565 |
| NELL2 | -0.3173926 |
| CD86 | -0.3181479 |
| MAOA | -0.3191870 |
| IGF2 | -0.3192159 |
| IVD | -0.3197553 |
| CPLX1 | -0.3198052 |
| MRPS30 | -0.3202693 |
| OSCP1 | -0.3204963 |
| ADCY9 | -0.3209079 |
| PRR15 | -0.3211033 |
| RAB11FIP3 | -0.3217958 |
| HHAT | -0.3226877 |
| FAM63A | -0.3227216 |
| GPIHBP1 | -0.3230718 |
| ENPP5 | -0.3231547 |
| CNIH3 | -0.3239350 |
| TEKT2 | -0.3257061 |
| HSPB1 | -0.3260177 |
| SPANXB2 | -0.3267546 |
| TCEA3 | -0.3270505 |
| RMND1 | -0.3271394 |
| SCN4B | -0.3273839 |
| NOXA1 | -0.3291699 |
| HIST1H2AH | -0.3298280 |
| NAT8L | -0.3307359 |
| RGS5 | -0.3308242 |
| MYH11 | -0.3324452 |
| C1orf167 | -0.3327829 |
| SYT1 | -0.3329685 |
| MTL5 | -0.3334872 |
| GSTO2 | -0.3341099 |
| FDXR | -0.3341104 |
| GP2 | -0.3341558 |
| SERPINA11 | -0.3345770 |
| SCCPDH | -0.3346739 |
| SCNN1A | -0.3347084 |
| SMARCD3 | -0.3351563 |
| AFF3 | -0.3358207 |
| C2orf40 | -0.3358446 |
| LDHD | -0.3359826 |
| PLIN5 | -0.3362530 |
| STK39 | -0.3375536 |
| TCEAL4 | -0.3380722 |
| CMYA5 | -0.3384705 |
| RPA4 | -0.3385637 |
| LIN7A | -0.3391208 |
| HDC | -0.3391279 |
| FAM110B | -0.3397477 |
| DUSP13 | -0.3402617 |
| ERLIN2 | -0.3412139 |
| SALL2 | -0.3420583 |
| UGCG | -0.3422664 |
| CTTNBP2 | -0.3424360 |
| NECAB3 | -0.3425641 |
| VPS18 | -0.3442390 |
| ABLIM3 | -0.3453532 |
| USP35 | -0.3456461 |
| HEY2 | -0.3460154 |
| SCGB1D1 | -0.3463573 |
| REEP6 | -0.3470905 |
| DMRTC1 | -0.3473010 |
| TNNI3 | -0.3474665 |
| TTC18 | -0.3477929 |
| HTR7 | -0.3484024 |
| CXCL14 | -0.3488936 |
| POTEI | -0.3490106 |
| P4HTM | -0.3499265 |
| CRIPAK | -0.3499561 |
| SCGB1D2 | -0.3506195 |
| HEBP1 | -0.3534837 |
| SPINK4 | -0.3535795 |
| LRRC49 | -0.3545877 |
| MAGED2 | -0.3552353 |
| LAMB2 | -0.3554736 |
| SYTL2 | -0.3556981 |
| CXXC5 | -0.3561188 |
| RLN2 | -0.3567358 |
| SLC44A4 | -0.3573990 |
| TRIM58 | -0.3580304 |
| GALNT16 | -0.3582784 |
| REEP2 | -0.3583455 |
| MED13L | -0.3591777 |
| NPDC1 | -0.3596913 |
| SEZ6L2 | -0.3603176 |
| SHC2 | -0.3608766 |
| BCAS1 | -0.3611705 |
| KIF12 | -0.3612913 |
| FAM174A | -0.3618878 |
| CTNND2 | -0.3621531 |
| CELSR2 | -0.3622584 |
| CASC1 | -0.3642020 |
| CRIP1 | -0.3648675 |
| PNPLA4 | -0.3652690 |
| CACNG1 | -0.3655327 |
| IGFBP5 | -0.3659735 |
| FLRT3 | -0.3662603 |
| TCN1 | -0.3680649 |
| GPRC5A | -0.3681525 |
| KCNK15 | -0.3683502 |
| IL6ST | -0.3685552 |
| SLC1A1 | -0.3687940 |
| KIAA1324 | -0.3696933 |
| KRT18 | -0.3705364 |
| GDPD3 | -0.3709776 |
| FAM198B | -0.3718625 |
| C16orf45 | -0.3726840 |
| ASPN | -0.3733917 |
| GREB1 | -0.3736173 |
| GPER1 | -0.3736819 |
| SELENBP1 | -0.3737602 |
| FKBP10 | -0.3741686 |
| FBLL1 | -0.3745939 |
| SPOPL | -0.3758637 |
| OGN | -0.3760750 |
| ITPKA | -0.3760880 |
| NUDT12 | -0.3766240 |
| SLC1A2 | -0.3769509 |
| TMEM145 | -0.3781067 |
| SYTL4 | -0.3790197 |
| NME3 | -0.3792213 |
| CTSG | -0.3807094 |
| MISP | -0.3810976 |
| VAV3 | -0.3819968 |
| HIST1H2AG | -0.3826018 |
| NBEA | -0.3832205 |
| RBM24 | -0.3834893 |
| FAM183A | -0.3835834 |
| ANO1 | -0.3839175 |
| PKIB | -0.3842764 |
| OPLAH | -0.3856070 |
| FBXO15 | -0.3856803 |
| CTSF | -0.3857808 |
| FAM3B | -0.3862265 |
| DCDC2 | -0.3897874 |
| RAI2 | -0.3917180 |
| TSPAN13 | -0.3937442 |
| TCEAL1 | -0.3943162 |
| KITLG | -0.3943477 |
| NOVA1 | -0.3943860 |
| NRIP1 | -0.3952288 |
| SPDEF | -0.3958252 |
| SERPINA6 | -0.3959805 |
| CHAD | -0.3966896 |
| TMEM121 | -0.3974484 |
| PSD3 | -0.3978062 |
| ELP2 | -0.3984112 |
| AGTR1 | -0.3990155 |
| SPR | -0.3991631 |
| WNT3 | -0.3998227 |
| BAIAP3 | -0.4004707 |
| ADCY1 | -0.4024946 |
| LRRC17 | -0.4048875 |
| C4B | -0.4074830 |
| PALM | -0.4095253 |
| C9orf116 | -0.4101579 |
| REPS2 | -0.4107753 |
| POTED | -0.4111519 |
| C3orf18 | -0.4126494 |
| KCTD6 | -0.4128420 |
| RET | -0.4129510 |
| LRRC6 | -0.4130223 |
| SLC27A2 | -0.4135068 |
| NAT2 | -0.4142214 |
| BCL2 | -0.4144958 |
| WFDC2 | -0.4147297 |
| NXNL2 | -0.4157390 |
| SEMA3C | -0.4167785 |
| CLGN | -0.4171279 |
| GRP | -0.4183199 |
| LURAP1L | -0.4186751 |
| MYRIP | -0.4192834 |
| DBNDD2 | -0.4207787 |
| TMPRSS6 | -0.4230762 |
| C10orf82 | -0.4238786 |
| GLI3 | -0.4239577 |
| MATN3 | -0.4239800 |
| PCSK4 | -0.4265013 |
| MYB | -0.4275201 |
| CPA3 | -0.4309254 |
| ZNF703 | -0.4311598 |
| C1orf226 | -0.4311969 |
| AR | -0.4316013 |
| CHST8 | -0.4316420 |
| CST9L | -0.4382281 |
| SLC30A8 | -0.4396310 |
| AGL | -0.4407783 |
| MAST4 | -0.4417292 |
| GRPR | -0.4430272 |
| ZSWIM5 | -0.4431651 |
| CST9 | -0.4456079 |
| CCDC170 | -0.4460233 |
| CACNA1H | -0.4478265 |
| HPN | -0.4492620 |
| RBM11 | -0.4498373 |
| FBXO2 | -0.4498842 |
| SLITRK6 | -0.4500294 |
| FAM25A | -0.4504799 |
| MUM1L1 | -0.4506503 |
| ABAT | -0.4510017 |
| TPSAB1 | -0.4529146 |
| CYP4B1 | -0.4542856 |
| QDPR | -0.4570459 |
| LRG1 | -0.4580202 |
| CBLN2 | -0.4593182 |
| FAM47E | -0.4612352 |
| KLHDC9 | -0.4637931 |
| LYPD6B | -0.4655880 |
| POTEG | -0.4691022 |
| GDF15 | -0.4692815 |
| C5orf30 | -0.4711410 |
| PLA2G10 | -0.4716448 |
| ABCC8 | -0.4738539 |
| SLC22A5 | -0.4746627 |
| RGS11 | -0.4758490 |
| BPIFB1 | -0.4764559 |
| TMEM150C | -0.4768395 |
| TRH | -0.4779940 |
| NME5 | -0.4796749 |
| SYT13 | -0.4797808 |
| BMPR1B | -0.4819317 |
| IRS1 | -0.4862999 |
| STARD10 | -0.4890031 |
| CYP4X1 | -0.4920599 |
| KIAA1467 | -0.4925190 |
| RAMP1 | -0.4960727 |
| PLAT | -0.4963944 |
| FBXL16 | -0.4971706 |
| SUSD3 | -0.5003152 |
| WWP1 | -0.5032179 |
| DYNLRB2 | -0.5046746 |
| SLC19A2 | -0.5053472 |
| NOSTRIN | -0.5078250 |
| LRRC73 | -0.5087110 |
| ENTPD8 | -0.5113527 |
| IGF1R | -0.5162231 |
| CACNA2D2 | -0.5177611 |
| IGDCC3 | -0.5178096 |
| PPM1J | -0.5181616 |
| IL20 | -0.5233365 |
| CYP2B6 | -0.5294354 |
| BAI2 | -0.5296665 |
| PLCD4 | -0.5301790 |
| ABCA3 | -0.5309661 |
| TMC4 | -0.5311531 |
| PTPRT | -0.5333927 |
| ERBB4 | -0.5354722 |
| METRN | -0.5406277 |
| PDE8B | -0.5429558 |
| BEX1 | -0.5436083 |
| GAMT | -0.5481190 |
| MLPH | -0.5486087 |
| COX6C | -0.5603989 |
| THBS4 | -0.5608591 |
| RSPH1 | -0.5613631 |
| KCNF1 | -0.5623241 |
| ZMYND10 | -0.5638433 |
| CLIC6 | -0.5672022 |
| PPP1R3C | -0.5731235 |
| KCNJ3 | -0.5746799 |
| ACADSB | -0.5805189 |
| CGA | -0.5825250 |
| LRRC56 | -0.5887278 |
| RGS22 | -0.5911171 |
| PRRT2 | -0.5945695 |
| KIF5C | -0.5947360 |
| PGR | -0.5968419 |
| KCNE4 | -0.6005920 |
| TSPAN1 | -0.6085173 |
| DHRS2 | -0.6117031 |
| STMND1 | -0.6133695 |
| PCP2 | -0.6146410 |
| C1orf64 | -0.6178456 |
| ANKRD30A | -0.6185430 |
| TPRG1 | -0.6189865 |
| SERPINA3 | -0.6217972 |
| C6orf211 | -0.6219457 |
| SYBU | -0.6329604 |
| STC2 | -0.6459908 |
| MSMB | -0.6501106 |
| ELOVL2 | -0.6502599 |
| SERPINA5 | -0.6544332 |
| TBC1D9 | -0.6628724 |
| NPNT | -0.6756294 |
| PARD6B | -0.6848069 |
| ADIRF | -0.6895303 |
| FAM196A | -0.6941314 |
| IGFALS | -0.6987391 |
| ANXA9 | -0.7004544 |
| MAPT | -0.7011938 |
| TNNT1 | -0.7028022 |
| FAM134B | -0.7060004 |
| CCND1 | -0.7096940 |
| ZG16B | -0.7192155 |
| C19orf33 | -0.7211498 |
| EEF1A2 | -0.7298216 |
| SMIM22 | -0.7362087 |
| LPPR3 | -0.7419884 |
| THSD4 | -0.7546711 |
| LONRF2 | -0.7562920 |
| DACH1 | -0.7684871 |
| DNALI1 | -0.7805356 |
| SLC7A2 | -0.7860872 |
| ESR1 | -0.7885428 |
| CLSTN2 | -0.7916607 |
| DNAJC12 | -0.7927792 |
| FOXA1 | -0.7994779 |
| FSIP1 | -0.8111273 |
| SLC39A6 | -0.8449405 |
| CPB1 | -0.8544138 |
| PDZK1 | -0.8587006 |
| CCDC74B | -0.8729635 |
| RIMS4 | -0.8812252 |
| DOK7 | -0.8840761 |
| TFF3 | -0.8962178 |
| GATA3 | -0.8997103 |
| NAT1 | -0.9400928 |
| RERG | -0.9747143 |
| CA12 | -0.9819797 |
| GFRA1 | -1.0153051 |
| AGR2 | -1.0658309 |
| NPY1R | -1.0676894 |
| SCUBE2 | -1.1629564 |
| NKAIN1 | -1.1700459 |
| TFF1 | -1.3622478 |
| AGR3 | -1.3690006 |
# 2. Bar Plot
# Display the ranked fold changes.
# barplot(ranks)
# 3. Conduct analysis
# Run fgsea with 'pathwaysH' and 'ranks'.
#fgseaRes <- fgsea(pathwaysH, ranks)
fgseaRes <- fgsea(pathways = pathwaysH, stats = ranks, nproc = 1)| | | 0% | |=== | 5% | |======= | 10% | |========== | 14% | |============= | 19% | |================= | 24% | |==================== | 29% | |======================= | 33% | |=========================== | 38% | |============================== | 43% | |================================= | 48% | |===================================== | 52% | |======================================== | 57% | |=========================================== | 62% | |=============================================== | 67% | |================================================== | 71% | |===================================================== | 76% | |========================================================= | 81% | |============================================================ | 86% | |=============================================================== | 90% | |=================================================================== | 95% | |======================================================================| 100%
fgseaRes <- na.omit(fgseaRes)
fgseaResTidy <- fgseaRes %>%
as_tibble() %>%
arrange(desc(NES)) #order by NES
# Combine genes in leadingEdge with semicolons
fgseaResTidy$leadingEdge <- sapply(fgseaResTidy$leadingEdge, paste, collapse = ";")
fgseaResTidy <- fgseaResTidy[order(fgseaResTidy$padj), ]
# Show in a Tidy table.
kable(fgseaResTidy) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| pathway | pval | padj | log2err | ES | NES | size | leadingEdge |
|---|---|---|---|---|---|---|---|
| HALLMARK_ALLOGRAFT_REJECTION | 0.0000000 | 0.0000000 | 1.7741500 | 0.7691086 | 3.3556556 | 195 | CXCL9;CXCL13;GZMB;CCL13;CCL5;CD2;CD79A;CD3D;LTB;CCL4;GZMA;TAP1;LCK;IL2RB;STAT1;IRF4;CD3G;CD247;CDKN2A;CXCR3;CCL2;CCR5;ICAM1;CCL7;CCL19;HLA-DRA;HLA-E;IFNG;MMP9;SIT1;CD8A;FASLG;ZAP70;HLA-A;SOCS1;HCLS1;CD96;HLA-DMA;CD74;C2;IL2RG;CCR2;LCP2;TLR2;HLA-DOB;IL27RA;LYN;CTSS;GBP2;HLA-DQA1;SRGN;IL18RAP;FCGR2B;IL1B;PRKCB;IL2RA;IL15;NCF4;IRF8;CD40;B2M;IL18;TLR1;TRAT1;TNF;CD8B;IGSF6;GCNT1;ITK;PRF1;FGR;CCR1;LY75;CAPG;HLA-DMB;ITGAL;ITGB2;CRTAM;PSMB10;CD7;IFNGR1;PTPRC;HLA-G;CFP;MAP4K1;KLRD1;IFNAR2;FAS;IL7;CCL11;HLA-DOA;RIPK2;IL6;GPR65;CCND2;CD47;JAK2;CSK;CD28;CD4;NCK1;TLR6;PTPN6;IL16;IL10;STAT4;UBE2D1;HIF1A;WAS;IFNGR2;FLNA;IL4R;ETS1;EIF5A;CD40LG |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 0.0000000 | 0.0000000 | 1.4172759 | -0.6888435 | -2.9576228 | 190 | TFF1;NPY1R;GFRA1;CA12;TFF3;PDZK1;SLC39A6;SLC7A2;THSD4;CCND1;MAPT;ANXA9;ELOVL2;MSMB;STC2;SYBU;DHRS2;PGR;MLPH;ABCA3;IGF1R;SLC19A2;SLC22A5;ABAT;MAST4;AR;MYB;BCL2;SLC27A2;RET;ADCY1;NRIP1;GREB1;KRT18;SLC1A1;IL6ST;KCNK15;CELSR2;MED13L;UGCG;SCNN1A;ADCY9;HSPB8;AREG;PRSS23;RAB17;TPBG;FLNB;MPPED2;CELSR1;AMFR;RHOBTB3;ABHD2;GJA1;CHPT1;SLC24A3;RBBP8;IGFBP4;OLFM1;KRT19;EGR3;SULT2B1;SEC14L2;ARL3;SNX24;TTC39A;BAG1;PMAIP1;BHLHE40;ELOVL5;IL17RB;SIAH2;MYOF;LRIG1;ASB13;NCOR2;PEX11A;DYNLT3;RHOD;FKBP4;BLVRB;PTGES;CBFA2T3;WFS1 |
| HALLMARK_INFLAMMATORY_RESPONSE | 0.0000000 | 0.0000000 | 1.3030932 | 0.6544343 | 2.8578860 | 197 | CXCL9;MARCO;LAMP3;CXCL10;CCL5;CXCL11;CCR7;LCK;IL2RB;CCL2;ICAM1;CXCR6;CCL7;CCL17;IRF1;GPR183;CYBB;CD48;IL10RA;SLAMF1;CD70;AQP9;LCP2;TLR2;ADM;IL7R;LYN;CD69;EDN1;TNFSF10;EBI3;RNF144B;FPR1;IL18RAP;PLAUR;IL1B;CD14;PTAFR;IL15;RGS1;PTGER4;CD40;IL18;CHST2;TLR1;CD82;OSM;NMI;ICAM4;IL15RA;CX3CL1;EMP3;CMKLR1;TNFRSF9;PDE4B;RTP4;SLC31A2;SLC31A1;C3AR1;SELL;GCH1;CCL20;RIPK2;ADORA2B;IL6;LY6E;GPR132;NAMPT;BST2;PDPN;RHOG;KCNA3;RGS16;IL10;NOD2;TNFRSF1B;HIF1A;IFNGR2;CCRL2;IL4R;SLC7A1;KCNJ2 |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 0.0000000 | 0.0000000 | 1.2951231 | 0.7867012 | 3.1289752 | 94 | LAMP3;CXCL10;CXCL11;TAP1;GBP4;BATF2;PSMB9;ISG20;IFI30;IRF1;HLA-C;CD74;CASP1;GBP2;OASL;SAMD9L;USP18;C1S;IL15;NCOA7;EPSTI1;IFIH1;B2M;PSMB8;NMI;UBE2L6;RSAD2;IFI44L;RTP4;LAP3;MX1;SELL;PARP12;IFI44;IFIT3;OAS1;IL7;RIPK2;LY6E;CD47;PLSCR1;BST2;PSME2;CCRL2;IFIT2;IL4R;TMEM140;SP110;STAT2;PARP14;NUB1;IFI27;OGFR;TRIM14;TRIM26;PSMA3;TRIM21;IFI35 |
| HALLMARK_E2F_TARGETS | 0.0000000 | 0.0000000 | 1.1421912 | 0.6093810 | 2.6587568 | 195 | CDKN2A;CCNE1;MELK;KIF2C;TFRC;CDC20;EZH2;MYBL2;DLGAP5;NASP;DEK;MCM5;CHEK1;SPAG5;MCM2;CDK1;MTHFD2;LBR;HMGB3;MCM6;PTTG1;DONSON;CDCA8;HMGA1;MCM4;CDC25B;TUBB;TOP2A;AURKA;MCM3;KPNA2;KIF4A;ANP32E;CKS1B;CCNB2;CDKN3;CDCA3;STMN1;BIRC5;PRDX4;RRM2;CTPS1;LMNB1;UBE2T;MMS22L;ORC6;NCAPD2;RFC2;SYNCRIP;HMMR;MCM7;CENPE;RANBP1;SPC25;SNRPB;SMC6;CKS2;MAD2L1;DSCC1;CDC25A;PLK1;RAD51AP1;E2F8;NUP153;ZW10;NUP205;CHEK2;TRIP13;XRCC6;AURKB;SMC4;ATAD2;ASF1A;RNASEH2A;CENPM;RAD1;DDX39A;PCNA;BUB1B;DIAPH3;EXOSC8;USP1;SSRP1;PRIM2;TACC3;POLA2;MKI67;TK1;DNMT1;RPA2;DEPDC1;TCF19;EED;RAN;KIF18B;LYAR;HELLS;HMGB2;GINS1;TRA2B;ASF1B;SRSF2;MSH2;RFC3;CDK4;WEE1;LIG1;GINS4;NUDT21;PLK4;PHF5A;CDKN1A;BRCA2;POLD1;PRPS1;NME1 |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.0000000 | 0.0000000 | 1.0768682 | 0.5844195 | 2.5521342 | 197 | CXCL10;CCL5;CXCL11;CCL4;TAP1;SOD2;CXCL1;CCL2;ICAM1;IRF1;BIRC3;KYNU;GPR183;PLEK;TLR2;IL7R;CD83;CD69;EDN1;NFIL3;CEBPB;BCL2A1;PLAUR;IL1B;TNFAIP8;PTGER4;IFIH1;IL18;TRAF1;PLAU;RCAN1;NFKBIE;TNF;EGR2;IL15RA;B4GALT5;DUSP2;TNFRSF9;PDE4B;TNFAIP3;TNFAIP2;CD44;CFLAR;PNRC1;SGK1;RELB;GCH1;DUSP4;ZFP36;CCL20;SAT1;BTG3;RIPK2;MARCKS;VEGFA;IL6;EHD1;SLC2A6;NAMPT;ZC3H12A;STAT5A;IL23A;MCL1;PHLDA2;DRAM1;SERPINB8;ID2;TRIB1;LITAF;FUT4;TUBB2A;IFNGR2;CCRL2;TANK;IFIT2;GADD45A;MAP2K3;MAP3K8;GFPT2;MAFF;SOCS3;CXCL2;LDLR;JUNB;SPSB1;SNN;PANX1;SPHK1 |
| HALLMARK_COMPLEMENT | 0.0000000 | 0.0000000 | 1.0574636 | 0.5917075 | 2.5953384 | 198 | S100A9;GZMB;CCL5;GZMA;GZMK;LCK;CXCL1;C1QA;PSMB9;PLA2G7;CP;IRF1;LTF;KYNU;C1QC;PLEK;CTSC;C2;CTSV;LCP2;CASP1;APOBEC3G;SPOCK2;LYN;CTSS;FCER1G;APOC1;CEBPB;SERPING1;PIM1;PLAUR;CASP5;C1S;CASP4;DUSP6;CTSL;C3;FCN1;CTSH;PFN1;ITGAM;LGMN;LAP3;TNFAIP3;C1R;APOBEC3F;FYN;PREP;CTSB;GNGT2;CASP10;PHEX;GNB4;IL6;PIK3CG;CR2;EHD1;JAK2;CFH;PLSCR1;CPM;RHOG;ME1;PDP1;S100A12;PCSK9;WAS;LGALS3;CASP3;XPNPEP1;CTSD;CD40LG;PLA2G4A;COL4A2;MAFF;KIF2A;SERPINA1 |
| HALLMARK_G2M_CHECKPOINT | 0.0000000 | 0.0000000 | 0.9865463 | 0.5739736 | 2.4989387 | 188 | KIF2C;CDC45;CENPA;CDC20;TTK;EZH2;MYBL2;NASP;ODC1;BUB1;SLC7A5;NDC80;MCM5;CHEK1;MCM2;CDK1;LBR;HMGB3;MCM6;UCK2;PTTG1;HMGA1;TPX2;EXO1;CDC25B;CCNA2;UBE2C;TOP2A;AURKA;MCM3;E2F3;KPNA2;MT2A;KIF4A;CKS1B;CCNB2;CDKN3;KIF11;STMN1;E2F1;BIRC5;MARCKS;RAD54L;LMNB1;E2F2;AMD1;ORC6;FBXO5;SYNCRIP;HMMR;CENPE;CENPF;INCENP;PML;SAP30;CKS2;CUL1;MAD2L1;NUP50;CDC25A;PLK1;KIF15;HIF1A;CDC7;TFDP1;SLC7A1;AURKB;SMC4;KIF23;PRC1;KATNA1;DDX39A;SQLE;FANCC;PRIM2;TACC3;POLA2;POLQ;MKI67;TROAP;HSPA8;RPA2 |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.0000000 | 0.0000000 | 0.9759947 | 0.7017615 | 2.7488341 | 87 | CXCL9;CXCL13;CD38;CXCL10;CXCL11;LTB;STAT1;CXCL1;CCL7;IRF1;SOCS1;IL2RG;TLR2;TNFRSF21;EBI3;PIM1;IL1B;CD14;IL2RA;TNF;IL15RA;CCR1;IFNGR1;CD44;FAS;IL7;BAK1;IL17RA;IL6;MYD88;CSF2RA;IL3RA;IL1R2;TNFRSF1B;IFNGR2;PTPN2;IL4R;PLA2G2A;IL10RB;A2M;STAT2;MAP3K8;SOCS3;ITGA4 |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 0.0000000 | 0.0000000 | 0.9759947 | -0.5630857 | -2.4299770 | 192 | TFF1;SCUBE2;NPY1R;AGR2;CA12;TFF3;PDZK1;DNAJC12;CCND1;MAPT;ANXA9;SERPINA5;SERPINA3;DHRS2;PGR;COX6C;ABCA3;CACNA2D2;SLC22A5;TPSAB1;CHST8;MYB;BCL2;SLC27A2;RET;NRIP1;TSPAN13;GPER1;IL6ST;CELSR2;CXCL14;SCNN1A;HSPB8;ACOX2;AREG;PRSS23;SORD;TPBG;FGFR3;CPE;FLNB;AMFR;ASCL1;TFPI2;ABHD2;RABEP1;CA2;CHPT1;SLC24A3;PTGER3;RBBP8;IGFBP4;OLFM1;KRT19;EGR3;SULT2B1;UGDH;ARL3;BAG1;PDCD4;ELOVL5;DLG5;IL17RB;SIAH2;MYOF;CYP4F11;PLXNB1;IGSF1;NCOR2;DYNLT3;FKBP4;BLVRB;PTGES;CAV1;WFS1;ST6GALNAC2;MOCS2 |
| HALLMARK_MTORC1_SIGNALING | 0.0000000 | 0.0000000 | 0.9214260 | 0.5440736 | 2.3673218 | 194 | PSAT1;PHGDH;DAPP1;FADS2;IFI30;CORO1A;PDK1;CTSC;TFRC;DDIT4;SLA;PNP;NFIL3;FGL2;CXCR4;GLRX;GMPS;BUB1;SLC7A5;MCM2;MTHFD2;ASNS;MCM4;ITGB2;LGMN;ACTR3;ENO1;TUBA4A;DHCR7;AURKA;IFRD1;TES;CFP;ARPC5L;PGM1;SRD5A1;VLDLR;RRM2;PSMG1;IDI1;PPA1;NAMPT;SDF2L1;ME1;PSPH;RPN1;SCD;SHMT2;EGLN3;PITPNB;CDC25A;PLK1;HMGCS1;PFKL;SLC1A5;IDH1;STARD4;EDEM1;NFKBIB;NUP205;HSP90B1;HMBS;SSR1;ACTR2;PSMA4;MAP2K3;STIP1;DDX39A;EEF1E1;LDLR;CALR;SQLE;PSMC2;PSMA3;PSMC4;GAPDH;PSMD14;CCT6A;PSMB5;AK4;GPI;TOMM40;PRDX1;GOT1;UCHL5;FKBP2;SLC37A4;TPI1;EBP;BCAT1 |
| HALLMARK_IL2_STAT5_SIGNALING | 0.0000000 | 0.0000000 | 0.8266573 | 0.5087151 | 2.2134730 | 194 | CXCL10;LTB;GBP4;IL2RB;ICOS;IRF4;CCNE1;CD79B;CD48;SOCS1;IL10RA;TNFRSF8;PNP;TNFRSF21;BATF3;CD83;GLIPR2;NFIL3;FGL2;TNFSF10;EOMES;PIM1;IL2RA;TNFRSF4;IRF8;ODC1;TRAF1;UCK2;CTLA4;CAPG;BATF;TNFRSF9;PLIN2;IFNGR1;CST7;CTSZ;CD44;ADAM19;SELL;NDRG1;RRAGD;TGM2;IGF2R;GPR65;CCND2;CKAP4;ITGA6;PLSCR1;IL3RA;GALM;TTC39B;RGS16;IL10;IL1R2;TNFRSF1B;LRRC8C;SLC1A5;CDC42SE2;PRKCH;DCPS;IL4R;CASP3;ETV4;MAP3K8;NCS1;MAFF;GSTO1;SMPDL3A;CDCP1;PUS1;RHOH;S100A1;FLT3LG;PDCD2L;NOP2;TIAM1;PTRH2;CCND3;RABGAP1L;COCH;NT5E;ANXA4 |
| HALLMARK_MYC_TARGETS_V1 | 0.0000000 | 0.0000000 | 0.8012156 | 0.4983984 | 2.1655272 | 193 | PSMD3;CDC45;CDC20;PSMB3;DEK;ODC1;MCM5;MCM2;MCM6;MCM4;CCNA2;RFC4;SRPK1;IFRD1;TYMS;KPNA2;PRDX4;HDAC2;CTPS1;ILF2;SYNCRIP;MCM7;PSMB2;RANBP1;EIF4A1;CUL1;MAD2L1;FBL;PPM1G;YWHAQ;PABPC1;TFDP1;XRCC6;SNRPA1;PSMA4;MRPL9;SRM;U2AF1;PCNA;LSM2;SERBP1;USP1;SNRPD3;SNRPA;HDGF;PSMC4;UBE2L3;CSTF2;PSMA7;PSMD14;PSMD7;SNRPG;RAN;GLO1;STARD7;CCT4;CAD;POLE3;SF3B3;COX5A;RPS10;TRA2B;LDHA;PGK1;SRSF2;CCT7;PSMD8;ABCE1;CCT3;SET;DDX21;TCP1;EIF3D;CDK4;SMARCC1;UBA2;C1QBP;APEX1;SRSF3;NME1;NCBP1;SNRPD1;AP3S1;HNRNPA2B1;PRPF31;SSBP1;HDDC2;EIF2S1;NOLC1;PSMA6;NOP16;RPS6;NOP56;ORC2;EXOSC7;XPO1;LSM7;PSMA2 |
| HALLMARK_KRAS_SIGNALING_UP | 0.0000000 | 0.0000001 | 0.7195128 | 0.4663767 | 2.0334575 | 191 | CXCL10;MYCN;ADAMDEC1;ST6GAL1;LCP1;SLPI;MMP9;HSD11B1;BIRC3;KCNN4;IL10RA;LAPTM5;IL2RG;GALNT3;TMEM176B;IL7R;CTSS;FCER1G;PLAUR;IL1B;CD37;CXCR4;ADAM8;GLRX;IRF8;TRAF1;PSMB8;MPZL2;PLAU;TMEM176A;CLEC4A;DUSP6;CMKLR1;TLR8;ITGB2;TNFAIP3;LY96;IKZF1;PRDM1;MAP4K1;C3AR1;PCP4;CCL20;GPRC5B;CCND2;CFH;CSF2RA;TMEM158;LAT2;MALL;ID2;RGS16;TRIB1;TNFRSF1B;GYPC;GPNMB;ETS1;ALDH1A3;SOX9;MAFB;ETV4;GFPT2;PCSK1N;DOCK2 |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 0.0005460 | 0.0016057 | 0.4772708 | 0.4897156 | 1.8347666 | 72 | FADS2;S100A11;CBS;NFIL3;PLAUR;LGMN;DHCR7;SREBF2;PNRC1;FDPS;GLDC;CXCL16;FBXO6;IDI1;MVD;ACAT2;PLSCR1;SCD;HMGCS1;STARD4;LGALS3;LDLR;FABP5;SQLE;ANXA5;TNFRSF12A;ATF3;ACTG1;EBP;ECH1;ATF5;PCYT2;NSDHL |
| HALLMARK_APOPTOSIS | 0.0005291 | 0.0016057 | 0.4772708 | 0.3811740 | 1.6287138 | 159 | CD38;CD2;TAP1;SOD2;ISG20;IRF1;BIRC3;FASLG;ERBB2;CASP1;CD69;TNFSF10;IL1B;CD14;CASP4;IL18;TNF;PRF1;BID;CDC25B;TOP2A;IFNGR1;CD44;CFLAR;GCH1;FAS;SAT1;BTG3;IGF2R;TSPO;IL6;CCND2;MCL1;ANXA1 |
| HALLMARK_MITOTIC_SPINDLE | 0.0005929 | 0.0016469 | 0.4772708 | 0.3616067 | 1.5791205 | 197 | KIF2C;TTK;DLGAP5;BUB1;NDC80;CDC42EP1;CDK1;TPX2;ANLN;TOP2A;TUBA4A;AURKA;KIF4A;CCNB2;KIF11;PIF1;BIRC5;MARCKS;ARHGAP4;LMNB1;FBXO5;ARHGAP27;CENPE;CENPF;BIN1;INCENP;NCK1;ECT2;SUN2;PLK1;KIF15;FLNA;SMC4;KIF23;PRC1;MID1;EPB41L2;KATNA1;DOCK2;TUBD1;GEMIN4;ACTN4;MYH9;CAPZB;KNTC1;ARHGEF2;SSH2;GSN;CSNK1D;ARHGAP10;NCK2;EZR;MYO9B;TIAM1;RANBP9;ABI1;VCL;DYNLL2;DYNC1H1;MAP1S;ARHGEF3;PLEKHG2;SAC3D1;NEK2;MAPRE1;MYO1E;BRCA2;PAFAH1B1;RACGAP1;CEP57;CKAP5;CDK5RAP2;TUBGCP3;RASAL2;NEDD9;MAP3K11;CEP72;RASA2;RHOF;NUSAP1;DLG1 |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.0014503 | 0.0038165 | 0.4550599 | 0.4222433 | 1.6973162 | 106 | PSAT1;CCL2;SPCS3;DDIT4;CEBPB;SLC7A5;HERPUD1;MTHFD2;ASNS;NABP1;CKS1B;VEGFA;PDIA5;KDELR3;DNAJB9;ATF4;EIF4G1;PDIA6;EIF4A1;TUBB2A;EDEM1;CHAC1;HSP90B1;SSR1;CEBPG;HYOU1;CALR;GEMIN4;PREB;TATDN2;ALDH18A1;ATF3;SRPRB;POP4;BANF1 |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 0.0019390 | 0.0048475 | 0.4550599 | 0.4097970 | 1.6525140 | 104 | LCK;DAPP1;FASLG;PDK1;IL2RG;SLA;PRKCB;CXCR4;CDK1;PFN1;ACTR3;MAPK1;E2F1;MYD88;CFL1;NCK1;RPS6KA3;NFKBIB;HSP90B1;ACTR2;STAT2;MAP2K3;CALR;MAP3K7;PPP1CA;PAK4;NOD1;TIAM1;SFN;TRAF2;RAF1;CAB39;ARF1;CDK4;RPS6KA1;CSNK2B;RIPK1;CDKN1A;AP2M1;MKNK1;MAPKAP1;EGFR;GSK3B;PLCG1;AKT1 |
| HALLMARK_COAGULATION | 0.0020941 | 0.0049858 | 0.4317077 | 0.3790204 | 1.5848998 | 137 | MMP1;KLK8;C1QA;MMP9;MMP3;PLEK;MMP7;C2;CTSV;APOC1;SERPING1;FGG;C1S;PLAU;DUSP6;C3;CTSH;LGMN;SH2B2;C1R;FYN;PREP;APOC2;CTSB |
| HALLMARK_P53_PATHWAY | 0.0029576 | 0.0064553 | 0.4317077 | 0.3373912 | 1.4710652 | 191 | TAP1;KLK8;CDKN2A;KRT17;CLCA2;IFI30;SOCS1;DDIT4;CASP1;SDC1;TM4SF1;PERP;TCN2;CD82;ST14;LDHB;ADA;RHBDF2;STEAP3;UPP1;S100A4;FAS;NDRG1;BAK1;SAT1;CCND2;ALOX15B;CEBPA;GM2A;DRAM1;TPD52L1;VDR;RGS16;S100A10;CTSD;GADD45A;SEC61A1;DEF6;PCNA;SERPINB5;TRAF4;NOTCH1;RPS12;APP;SPHK1;ITGB4;BAX |
| HALLMARK_MYOGENESIS | 0.0029694 | 0.0064553 | 0.4317077 | -0.3596906 | -1.5550511 | 196 | TNNT1;STC2;PPP1R3C;CACNA1H;AGL;SPDEF;CACNG1;MYH11;ADCY9;CAMK2B;HSPB8;PGAM2;PVALB;OCEL1;ERBB3;PFKM;CLU;CD36;BAG1;NQO1;LAMA2;SGCD;BHLHE40;TNNC2;ITGA7;TNNT3;FKBP1B;SSPN;MYOM2;CKMT2;MYBPH;COX7A1;SH3BGR;PPFIA4;REEP1;VIPR1;TSC2;CHRNG;SGCG;SH2B1;SGCA;SPARC;HRC;COL6A3;HDAC5;KCNH2;ITGB5;MAPRE3;MYL7;CFD;FABP3;ENO3;NCAM1;COL1A1;COL3A1;MYL6B;GNAO1;SORBS1;RB1;GABARAPL2;FST;FXYD1;TNNC1;MYH4;PSEN2;HSPB2;EIF4A2;CDH13;CAV3 |
| HALLMARK_HYPOXIA | 0.0044904 | 0.0093551 | 0.4070179 | 0.3305602 | 1.4412814 | 191 | ISG20;PFKP;CP;TMEM45A;CSRP2;PDK1;PLAC8;DDIT4;ADM;NFIL3;PIM1;PLAUR;CXCR4;GLRX;EDN2;CHST2;LDHC;TNFAIP3;ENO1;PLIN2;TES;S100A4;MT2A;SLC2A5;PNRC1;ZFP36;NAGK;NDRG1;RRAGD;PGM1;TGM2;VEGFA;VLDLR;ADORA2B;IL6;TPST2;KDELR3;TGFBI;SAP30;UGP2;PFKL;XPNPEP1;ETS1;HEXA;MAFF;MYH9;GAPDH;AMPD3;GCNT2;AK4;GPI;KLF7;ATF3;HS3ST1;SLC37A4;TPI1;LXN;ANXA2;TKTL1;JMJD6;LDHA;PGK1;DCN;FOXO3;KLHL24;PKP1;SLC2A3;HOXB9;CASP6 |
| HALLMARK_GLYCOLYSIS | 0.0086300 | 0.0172599 | 0.3807304 | 0.3199596 | 1.3972496 | 197 | B3GNT3;ISG20;PFKP;CENPA;DDIT4;SDC1;MED24;NASP;CXCR4;GLRX;SPAG4;CHST2;CDK1;SLC16A3;LDHC;KIF20A;ENO1;AURKA;CD44;AKR1A1;RRAGD;DSC2;STMN1;CHST6;VEGFA;VLDLR;ADORA2B;B3GAT1;KDELR3;HMMR;TGFBI;ME1;SAP30;UGP2;EGLN3;IDH1;SOX9;PLOD1;MET;KIF2A;PYGB;PSMC4;CHST12;DEPDC1;AK4;ELF3;PKM;PGAM1;GMPPB;ME2;COPB2;GALK2;GOT1;TXN;SLC25A13;SDHC;SLC37A4;NT5E;TPI1;TKTL1;B4GALT4;LHPP;LDHA;PGK1;DCN;RPE |
| HALLMARK_UV_RESPONSE_UP | 0.0095583 | 0.0183814 | 0.3807304 | 0.3390797 | 1.4382660 | 154 | TAP1;SOD2;STARD3;HLA-F;CCNE1;ICAM1;GAL;IRF1;TFRC;CTSV;LYN;GGH;ASNS;BID;CHRNA5;RFC4;TUBA4A;MGAT1;FEN1;FMO1;GCH1;CCK;BAK1;BTG3;IL6;ARRB2;AMD1;LHX2;RPN1;AGO2;RAB27A;ALAS1;CASP3;CEBPG;PARP2;STIP1;CXCL2;JUNB;RASGRP1;NFKBIA;SIGMAR1;CDC34;ATF3;KLHDC3;POLE3;CCND3;PPIF;PRPF3;CREG1;NKX2-5;EPCAM;YKT6;DDX21;NPTX2;POLR2H |
| HALLMARK_MYC_TARGETS_V2 | 0.0099537 | 0.0184328 | 0.3807304 | 0.4380292 | 1.5653730 | 57 | MCM5;MCM4;DUSP2;BYSL;PLK1;NIP7;SRM;PUS1;NOP2;PPAN;NDUFAF4;RCL1;PPRC1;PES1;CDK4;MYBBP1A;MAP3K6;PLK4;LAS1L;WDR74;SLC19A1;MPHOSPH10;NOLC1;NOP16;NOP56;TMEM97;EXOSC5;SUPV3L1;WDR43 |
| HALLMARK_APICAL_JUNCTION | 0.0136667 | 0.0244048 | 0.3807304 | 0.3228006 | 1.4059075 | 190 | GRB7;CDH3;ICAM1;MMP9;ACTG2;VCAM1;SYK;CD274;MDK;RAC2;TRAF1;MPZL2;ICAM2;MSN;ICAM4;CX3CL1;PFN1;PTPRC;CNN2;ALOX15B;MVD;ADAM15;TGFBI;NRTN;CLDN4;ZYX;CAP1;ACTB;RSU1;VASP;CD99;ATP1A3;EPB41L2;ARPC2;ACTN1;YWHAH;ACTN4;MYH9;ITGB4;LAMC2;ITGA9;CLDN14;MPZL1;SLC30A3;CALB2;NFASC;CDH1;SIRPA;MAPK13 |
| HALLMARK_UV_RESPONSE_DN | 0.0157129 | 0.0270912 | 0.3524879 | -0.3457458 | -1.4243774 | 138 | IGF1R;IRS1;IGFBP5;SRI;GJA1;APBB2;CDON;INPP4B;AMPH;MMP16;MAGI2;SLC22A18;PRKCE;SMAD3;BHLHE40;DDAH1;PDGFRB;CDKN1B;ICA1;MGMT;CAV1;ITGB3;SYNJ2;RUNX1;AGGF1;CAP2;PTPRM;LAMC1;MIOS;COL1A2;BDNF;DBP;TGFBR3;SNAI2;COL1A1;COL3A1;PIAS3;CDC42BPA;YTHDC1;PTEN;SCN8A;DLC1 |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 0.0465523 | 0.0750843 | 0.3217759 | 0.4194947 | 1.4502975 | 47 | SOD2;PFKP;GLRX;MGST1;PRDX4;FTL;PDLIM1;LSP1;JUNB;NDUFA6;PRDX1;TXN;NDUFS2;FES |
| HALLMARK_ADIPOGENESIS | 0.0453630 | 0.0750843 | 0.3217759 | -0.3046008 | -1.3144943 | 192 | QDPR;CYP4B1;REEP6;HSPB8;EPHX2;REEP5;SPARCL1;LTC4S;PTGER3;DGAT1;CD36;SULT1A1;CMBL;SNCG;PDCD4;DBT;LIPE;ITGA7;FABP4;LEP;SSPN;ADIPOR2;CIDEA;ACADS;LIFR;ADCY6;OMD;MRAP;LPCAT3;GPAM;GPHN;ADIPOQ;CD151;UQCRQ;TOB1;MAP4K3;SLC27A1;PHLDB1;FAH;MTCH2;PRDX3;GPX4;CCNG2;SCARB1;NDUFA5;SOD1;CYC1;ETFB;RMDN3;SCP2;ALDOA;SORBS1;BAZ2A;ELOVL6;ELMOD3;COQ5;UQCR11;COX6A1 |
| HALLMARK_KRAS_SIGNALING_DN | 0.1062356 | 0.1659931 | 0.2089550 | 0.2787514 | 1.2153888 | 191 | CALML5;PNMT;TCL1A;PDCD1;KLK8;IFNG;AKR1B10;EDN1;SLC6A14;KRT5;EDN2;CHST2;SOX10;PRODH;LGALS7;RSAD2;IFI44L;TCF7L1;GPR19;MX1;SGK1;KRT15;TFAP2B;SCGB1A1;CAMK1D;TGM1;KRT4;RYR1;KLK7;KCNMB1;YPEL1;STAG3;CD40LG;GTF3C5;TFF2;SNN;SPRR3;SPTBN2;CDKAL1;SLC30A3;CD80;CLPS;GP1BA |
| HALLMARK_SPERMATOGENESIS | 0.1392694 | 0.2110143 | 0.1797823 | 0.2870184 | 1.1892770 | 132 | IL12RB2;KIF2C;DPEP3;TTK;EZH2;ART3;BUB1;RPL39L;CDK1;LDHC;POMC;GFI1;RFC4;AURKA;SLC2A5;CCNB2;CDKN3;CRISP2;PSMG1;LPIN1 |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 0.1558140 | 0.2160153 | 0.1709323 | 0.2675581 | 1.1673682 | 195 | MMP1;DKK1;CXCL1;IL32;MMP3;VCAM1;SDC1;PLAUR;IL15;WIPF1;EMP3;CAPG;TNFAIP3;CD44;TPM4;FAS;FBLN2;SFRP1;SAT1;TGM2;VEGFA;IL6;FBLN5;MCM7;TGFBI;NNMT;ID2;COLGALT1;PPIB;FLNA;GAS1;CRLF1;MFAP5;GADD45A;GPX7;PLOD1;COL4A2;CTHRC1 |
| HALLMARK_ANDROGEN_RESPONSE | 0.1598513 | 0.2160153 | 0.1492075 | -0.3094693 | -1.1909549 | 96 | CCND1;BMPR1B;SPDEF;STK39;SORD;GPD1L;ABHD2;HPGD;KRT19;INPP4B;ELOVL5;ACSL3;AKAP12;STEAP4;LIFR;KRT8;APPBP2 |
| HALLMARK_BILE_ACID_METABOLISM | 0.1469534 | 0.2160153 | 0.1531588 | -0.3001903 | -1.1956220 | 112 | ABCA3;AR;SLC27A2;SERPINA6;NUDT12;FDXR;EPHX2;PFKM;SULT2B1;SLC22A18;ISOC1;PEX11G;HSD17B4;LIPE;DIO1;CROT;PEX11A;PEX12;BCAR3;ABCA5;PEX19;SLC27A5;ABCA9;EFHC1 |
| HALLMARK_HEDGEHOG_SIGNALING | 0.1513043 | 0.2160153 | 0.1482615 | -0.3963835 | -1.2549384 | 35 | HEY2;CELSR1;HEY1;GLI1;NRCAM;CRMP1;RASA1;TLE3;UNC5C;RTN1 |
| HALLMARK_XENOBIOTIC_METABOLISM | 0.1690141 | 0.2223870 | 0.1644058 | 0.2646495 | 1.1515179 | 194 | HSD17B2;PTGDS;TDO2;HSD11B1;KYNU;AQP9;TMEM176B;PAPSS2;IRF8;ALDH2;PSMB10;COMT;UPP1;XDH;APOE;MT2A;FMO1;GCH1;FAS;ABCC3;PGD;CES1;CYP27A1;DDC;SLC35B1;VNN1;SHMT2;ID2;SLC1A5;IDH1;POR;ALAS1;PGRMC1;GSTO1;NPC1;ARG2;MTHFD1;SPINT2;MAN1A1;NDRG2;SMOX;GCNT2 |
| HALLMARK_NOTCH_SIGNALING | 0.1922399 | 0.2464614 | 0.1307771 | -0.3941583 | -1.2118616 | 32 | CCND1;HEYL;SKP1;JAG1;KAT2A;ARRB1 |
| HALLMARK_ANGIOGENESIS | 0.2482270 | 0.3102837 | 0.1133129 | -0.3658246 | -1.1522186 | 36 | SERPINA5;POSTN;FGFR1;PTK2;JAG1;PDGFA;MSX1;PF4;STC1;COL3A1;JAG2 |
| HALLMARK_APICAL_SURFACE | 0.2546296 | 0.3105239 | 0.1301056 | 0.3403906 | 1.1547416 | 43 | IL2RB;MAL;GHRL;IL2RG;LYN;PLAUR;CX3CL1;ATP6V0A4;AKAP7;PCSK9;RHCG;GAS1;EPHB4;APP |
| HALLMARK_PEROXISOME | 0.2735675 | 0.3256756 | 0.1096841 | -0.2789097 | -1.0942688 | 104 | ABCC8;SEMA3C;SLC27A2;SERPINA6;EPHX2;ABCC5;CRABP2;ALB;SULT2B1;ISOC1;ELOVL5;HSD17B4;DIO1;HMGCL;PEX11A;HSD11B2 |
| HALLMARK_FATTY_ACID_METABOLISM | 0.2839060 | 0.3301232 | 0.1059203 | -0.2590415 | -1.0809701 | 152 | BMPR1B;SLC22A5;REEP6;MAOA;HPGD;ECI1;CA2;LTC4S;ENO2;UGDH;CD36;AOC3;ELOVL5;HSD17B4;CRYZ;HMGCL;ADIPOR2;CIDEA;ACADS;NTHL1;ALDH3A2;INMT;ACOT2;GLUL;BLVRA;PDHB;ALAD;ETFDH;PCBD1;ENO3;PTPRG;AUH;ALDOA;SUCLA2;UROD;SERINC1;CA4;AQP7;CPT1A;HAO2;FASN;RAP1GDS1;HSD17B7;SUCLG2 |
| HALLMARK_PANCREAS_BETA_CELLS | 0.2989510 | 0.3397171 | 0.1006334 | -0.3384988 | -1.0991474 | 40 | SYT13;ABCC8;CHGA;PCSK1;STXBP1;SRP14 |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 0.5545927 | 0.6162141 | 0.0665892 | -0.2834221 | -0.9413418 | 42 | HEY2;HEY1;HDAC11;FZD8;JAG1;AXIN2;NCOR2;KAT2A;LEF1;HDAC5;FRAT1;NOTCH4;DLL1;JAG2;GNAI1;PSEN2;DKK4 |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.6964912 | 0.7570557 | 0.0562941 | -0.2140800 | -0.9176021 | 184 | ACADSB;COX6C;MRPS30;PDK4;ECI1;NDUFA7;TIMM13;NDUFC2;RHOT2;ALDH6A1;NDUFA2;GLUD1;COX7C;CYB5A;UQCRQ;PDHB;ATP6V1H;ETFDH;PRDX3;NDUFS4;GPX4;ATP6V1C1;COX17;NDUFA5;UQCRB;NDUFA4;CYC1;MAOB;BDH2;ETFB;UQCRC2;SUCLA2;HSPA9;NDUFC1;PDHX;CPT1A;UQCR11;COX6A1;ATP6V1G1;SURF1;LRPPRC;GRPEL1;SLC25A20;ATP6V0C;SLC25A4;NNT;ACAT1;BCKDHA;RHOT1;ATP6AP1;NDUFS8;COX11;ATP1B1 |
| HALLMARK_PROTEIN_SECRETION | 0.8671587 | 0.9225092 | 0.0485060 | -0.2069298 | -0.7953761 | 94 | KRT18;ATP6V1B1;SCAMP1;ARFGEF1;AP2B1;TOM1L1;SSPN;ICA1;DST;RAB22A;STX16;TSG101;ARFIP1;COG2 |
| HALLMARK_DNA_REPAIR | 0.9455782 | 0.9648757 | 0.0540088 | 0.1803835 | 0.7601326 | 145 | HCLS1;PNP;ADA;PDE4B;RFC4;TYMS;FEN1;VPS37B;ALYREF;RFC2;SUPT5H;ZWINT;SEC61A1;POLR2D;GTF3C5;PCNA;NELFB;SSRP1;POLA2;CLP1;SF3A3;ADRM1;RPA2;NT5C3A;PDE6G;UPF3B;POLR2F;POLR1C;POLR2H;RFC3;LIG1;SAC3D1;NUDT21;UMPS;POLD1;NME1 |
| HALLMARK_TGF_BETA_SIGNALING | 0.9348592 | 0.9648757 | 0.0429311 | -0.2043230 | -0.7117620 | 54 | SMAD3;NCOR2;BCAR3;BMPR2;TRIM33;THBS1;PPM1A;APC;TJP1;KLF10;BMP2;XIAP;ARID4B;FURIN;SLC20A1;PMEPA1;SMAD1;CDK9;SPTBN1;FNTA;SERPINE1;SMAD7;LTBP2;LEFTY2;HDAC1;CTNNB1 |
| HALLMARK_HEME_METABOLISM | 0.9875887 | 0.9875887 | 0.0407404 | -0.1687180 | -0.7233403 | 189 | SELENBP1;TRIM58;HEBP1;CA2;TMEM9B;HAGH;TRAK2;DMTN;SLC22A4;VEZF1;GDE1;BTRC;BLVRB;ALDH6A1;PIGQ;NUDT4;HBB;ADD1;BLVRA;SNCA;RBM5;ERMAP;MXI1;ALAD;ABCG2;MBOAT2;FTCD;SLC30A1;FECH;RAP1GAP;EZH1;NFE2;ALDH1L1;TAL1;UROD;PRDX2;GCLM;RHCE;RNF123;EPOR;KLF3;SLC25A38;EIF2AK1;BCAM |
# Save fgseaRes as txt file.
write.table(fgseaResTidy, file.path(output_dir,"pathway_analysis","full_fgseaRes_HRank.txt"), sep = "\t", row.names = FALSE, quote = FALSE)
# Mark "significant" if adjusted p-value <= 0.05, else "non-significant".
fgseaResTidy$adjPvalue <- ifelse(fgseaResTidy$padj <= 0.05, "significant", "non-significant")
# Define colors for significance: grey for non-significant and red for significant results.
cols <- c("non-significant" = "grey", "significant" = "red")
# Using ggplot: reorder pathways by NES, fill bars based on significance, flip coordinates for readability.
ggplot(fgseaResTidy, aes(reorder(pathway, NES), NES, fill = adjPvalue)) + geom_col() +
scale_fill_manual(values = cols) + coord_flip() +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
labs(x = "Pathway", y = "Normalized Enrichment Score", title = "Hallmark pathways NES
Enrichment Score from GSEA")
# 4. GSEA Results Table Plot.
# Plot GSEA table for significant pathways (padj < 0.05) using a GSEA parameter of 0.5.
plotGseaTable(pathwaysH[fgseaRes$pathway[fgseaRes$padj < 0.05]], ranks, fgseaRes, gseaParam=0.5)
# 5. Enrichment score plot.
# For significant pathways # 14 pathways.
# Store the list of significant pathways (padj < 0.05).
significant_pathways <- fgseaRes$pathway[fgseaRes$padj < 0.05]
# Use a for loop to iterate and plot enrichment for each significant pathway
# for (i in significant_pathways) {
# enrichment_plot <- plotEnrichment(pathwaysH[[i]], ranks)
# enrichment_plot <- enrichment_plot + ggtitle(paste("Enrichment Plot for Pathway:",i))
# print(enrichment_plot)
# }
# Plot significant pathways as points with a gradient color based on p-value and size based on a 'size' variable.
ggplot(fgseaResTidy[fgseaResTidy$padj < 0.05, ], aes(y=reorder(pathway, size),x= NES)) + geom_point(aes(color=padj,size=size)) +
scale_color_gradientn(colours = c("red","blue")) +
labs(x='Normalized Enrichment Score', y=NULL ) +
theme( axis.title = element_text(face='bold'), axis.text = element_text (face='bold') )
KEGG Pathway Analysis
KEGG Pathway Analysis (Legacy + Medicus) * Used both
KEGG_LEGACY and KEGG_MEDICUS gene sets
* Significance cutoff for visualization: FDR < 0.05
* Output: full results in tab-delimited .txt files
KEGG_MEDICUS
#Load KEGG_MEDICUS pathways.
pathwaysKEGG_MED <- gmtPathways(file.path(input_dir, "c2.cp.kegg_medicus.v2023.2.Hs.symbols.gmt"))
# Perform fgsea with KEGG pathways
#fgseaRes_kegg <- fgsea(pathwaysKEGG_MED, ranks)
fgseaRes_kegg <- fgsea(pathways = pathwaysKEGG_MED, stats = ranks, nproc = 1)| | | 0% | |== | 3% | |==== | 6% | |====== | 9% | |======== | 11% | |========== | 14% | |============ | 17% | |============== | 20% | |================ | 23% | |================== | 26% | |==================== | 29% | |====================== | 31% | |======================== | 34% | |========================== | 37% | |============================ | 40% | |============================== | 43% | |================================ | 46% | |================================== | 49% | |==================================== | 51% | |====================================== | 54% | |======================================== | 57% | |========================================== | 60% | |============================================ | 63% | |============================================== | 66% | |================================================ | 69% | |================================================== | 71% | |==================================================== | 74% | |====================================================== | 77% | |======================================================== | 80% | |========================================================== | 83% | |============================================================ | 86% | |============================================================== | 89% | |================================================================ | 91% | |================================================================== | 94% | |==================================================================== | 97% | |======================================================================| 100%
# Organize and sort KEGG results by NES
fgseaResTidy_kegg <- fgseaRes_kegg %>%
as_tibble() %>%
arrange(desc(NES))
# Combine genes in leadingEdge with semicolons
fgseaResTidy_kegg$leadingEdge <- sapply(fgseaResTidy_kegg$leadingEdge, paste, collapse = ";")
# Show in a Tidy table of keg.
kable(fgseaResTidy_kegg) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| pathway | pval | padj | log2err | ES | NES | size | leadingEdge |
|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 0.0000000 | 0.0000088 | 0.7337620 | 0.7078958 | 2.3918550 | 44 | IL2RB;STAT1;IFNG;IL12RB2;IL2RG;IL7R;PIM1;IL2RA;IL15;IL15RA;IFNGR1;JAK3;IFNAR2;IL7;IL6;IL6R;JAK2;STAT5A;IL23A;IL3RA;STAT4;IFNGR2;IL4R;STAT2 |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES | 0.0000000 | 0.0000010 | 0.7881868 | 0.9360671 | 2.3402920 | 13 | HLA-DRA;HLA-DPA1;HLA-DRB5;HLA-DRB1;HLA-DQA2;HLA-DMA;HLA-DPB1;CD74;HLA-DQB1;HLA-DOB;HLA-DQA1;HLA-DMB;HLA-DOA |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION | 0.0000001 | 0.0000157 | 0.7049757 | 0.9083475 | 2.2709894 | 13 | HLA-DRA;HLA-DPA1;HLA-DRB5;HLA-DRB1;HLA-DQA2;HLA-DMA;HLA-DPB1;HLA-DQB1;HLA-DOB;HLA-DQA1;HLA-DMB;HLA-DOA |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 0.0000016 | 0.0001996 | 0.6435518 | 0.7746066 | 2.2562692 | 24 | CCNE1;CDC45;CDT1;MCM5;MCM2;MCM6;MCM4;CCNA2;MCM3;ORC6;CCNE2;MCM7;TICRR;CDC7 |
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0000013 | 0.0001996 | 0.6435518 | 0.7738713 | 2.2288285 | 23 | IL21R;IL2RB;STAT1;IL2RG;IL7R;IL2RA;IL15;IL15RA;JAK3;IL7;STAT5A;IL4R |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000058 | 0.0003751 | 0.6105269 | 0.6914568 | 2.2169521 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;APP;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;PSMC1;PSMC5;PSMA6;PSMA2 |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000061 | 0.0003751 | 0.6105269 | 0.6904449 | 2.2137077 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PRNP;PSMC3;PSMC1;PSMC5;PSMA6;PSMA2 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000032 | 0.0003223 | 0.6272567 | 0.6730571 | 2.1944573 | 39 | PSMD3;PSMB3;PSMB2;VCP;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;UBA52;PSMC1;PSMC5;PSMA6;PSMA2;RPS27A;PSMD1;PSMD6;UBC |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000115 | 0.0005467 | 0.5933255 | 0.6697191 | 2.1690928 | 38 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;UBA52;PSMC1;PSMC5;PSMA6;PSMA2;RPS27A;PSMD1;PSMD6;UBC |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000059 | 0.0003751 | 0.6105269 | 0.6634401 | 2.1631018 | 39 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;UBA52;PSMC1;PSMC5;PSMA6;PSMA2;RPS27A;PSMD1;PSMD6;UBC |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000233 | 0.0009629 | 0.5756103 | 0.6419621 | 2.1001915 | 40 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;DERL1;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;UBA52;PSMC1;PSMC5;PSMA6;PSMA2;RPS27A;PSMD1;PSMD6;UBC |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000282 | 0.0010911 | 0.5756103 | 0.8524810 | 2.0920706 | 12 | TAP1;HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;B2M;HLA-G;CALR;TAP2;TAPBP |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000552 | 0.0017097 | 0.5573322 | 0.6522022 | 2.0910937 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;PSMC1;PSMC5;PSMA6;PSMA2 |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0000436 | 0.0014980 | 0.5573322 | 0.7525326 | 2.0851665 | 19 | CD3D;LCK;CD3G;CD247;ZAP70;PLCG2;VAV1;LCP2;LAT;FYN;CD4;ITPR3 |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 0.0000509 | 0.0016567 | 0.5573322 | 0.8282620 | 2.0707650 | 13 | CCL5;CCL4;CCL2;CCL3;CX3CL1 |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 0.0000891 | 0.0023971 | 0.5384341 | 0.7526658 | 2.0664103 | 18 | CDC45;MCM5;MCM2;MCM6;MCM4;MCM3;PIF1;MCM7;VCP;GINS1;GINS4;CUL2;LRR1;GINS3;GINS2;RBX1 |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 0.0000816 | 0.0022952 | 0.5384341 | 0.7906926 | 2.0604141 | 15 | CDC45;MCM5;MCM2;MCM6;MCM4;MCM3;MCM7;VCP |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 0.0000943 | 0.0024314 | 0.5384341 | 0.6740776 | 2.0558059 | 30 | CDC45;MCM10;MCM5;MCM2;MCM6;MCM4;RFC4;MCM3;RFC2;MCM7;PCNA;PRIM2;WDHD1;POLA2;RPA2;POLE3;GINS1;POLE2;RFC3;GINS4 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0001050 | 0.0025989 | 0.5384341 | 0.6380350 | 2.0456707 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA4;PSMC2;PSMA3;PSMC4;PSMB4;ADRM1;PSMA7;PSMD14;PSMB5;PSMD7;PSMB6;PSMA5;PSMD12;PSMD8;PSMD13;PSMB1;PSMB7;PSMC3;PSMC1;PSMC5;PSMA6;PSMA2 |
| KEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION | 0.0000348 | 0.0012669 | 0.5573322 | 0.9040535 | 2.0388587 | 8 | MCM5;MCM2;MCM6;MCM4;MCM3;PIF1;MCM7 |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000036 | 0.0003223 | 0.6272567 | 0.9486887 | 2.0269467 | 7 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;B2M;HLA-G |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000099 | 0.0005151 | 0.5933255 | 0.9395603 | 2.0074431 | 7 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;HLA-G |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0003968 | 0.0087719 | 0.4984931 | 0.7475041 | 1.9826730 | 16 | CYBB;NCF1;NCF2;CYBA;NCF4;RAC2;FYN |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0003211 | 0.0076450 | 0.4984931 | 0.7873031 | 1.9683624 | 13 | MMP1;CCL2;MMP3;CYBB;ACE2;IL1B;TNF;IL6 |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 0.0008434 | 0.0156389 | 0.4772708 | 0.6490456 | 1.9371157 | 27 | CDC45;CDT1;MCM5;MCM2;MCM6;MCM4;MCM3;ORC6;MCM7;TICRR;ORC3;POLE3;GINS1;ORC1;CDC6;POLE2;GINS4 |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000183 | 0.0008077 | 0.5756103 | 0.9486346 | 1.9300215 | 6 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;HLA-G |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00482 | 0.0008843 | 0.0156389 | 0.4772708 | 0.8170157 | 1.9047031 | 9 | CCNE1;CCNA2;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0003505 | 0.0080351 | 0.4984931 | 0.8887598 | 1.8989040 | 7 | IL2RB;IL2RG;JAK3;STAT5A |
| KEGG_MEDICUS_REFERENCE_RECRUITMENT_AND_FORMATION_OF_THE_MCC | 0.0011169 | 0.0186850 | 0.4550599 | 0.8108525 | 1.8903349 | 9 | CDC20;TTK;BUB1;NDC80;MAD2L1;AURKB;BUB1B |
| KEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT | 0.0004485 | 0.0092544 | 0.4984931 | 0.8844019 | 1.8895930 | 7 | CP;TFRC;STEAP3;SLC11A2 |
| KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX | 0.0008387 | 0.0156389 | 0.4772708 | 0.7813302 | 1.8874379 | 11 | NDC80;SPAG5;NUF2;AURKA;CENPE;SPC25;AURKB;PPP1CA |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 0.0015825 | 0.0250646 | 0.4550599 | 0.7098118 | 1.8826985 | 16 | CENPW;NDC80;NUF2;CDCA8;BIRC5;INCENP;SPC25;ZWINT;AURKB;PMF1 |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0004361 | 0.0092544 | 0.4984931 | 0.6216829 | 1.8743383 | 29 | CYBB;NCF1;NCF2;CYBA;NCF4;RAC2;CREB3L2;FYN;MAPK1;ATF4;CREB3L1 |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 0.0028175 | 0.0365383 | 0.4317077 | 0.6871452 | 1.8736998 | 17 | WIPF1;ARPC1B;ACTR3;ARPC5L;NCK1;ACTB;ACTR2;ARPC2;ARPC5;NCK2;ARPC4;ACTG1;WIPF2;ARPC1A |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0018917 | 0.0285593 | 0.4550599 | 0.7171558 | 1.8687893 | 15 | FASLG;TNFSF10;BID;FAS;CASP10;BAK1;CASP3;BAX |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY | 0.0019487 | 0.0287202 | 0.4550599 | 0.7373308 | 1.8681086 | 14 | ARPC1B;ACTR3;ARPC5L;ACTB;ACTR2;ARPC2;ARPC5;ARPC4;ACTG1;ABI1;ARPC1A |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE | 0.0000625 | 0.0018421 | 0.5384341 | 0.9497777 | 1.8585869 | 5 | C1QA;C1QB;C1QC;C1S;C1R |
| KEGG_MEDICUS_REFERENCE_NON_CANONICAL_INFLAMMASOME_SIGNALING_PATHWAY | 0.0007438 | 0.0148526 | 0.4772708 | 0.8677997 | 1.8541212 | 7 | CASP1;IL1B;CASP5;CASP4;IL18;NLRP3;PYCARD |
| KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE | 0.0037367 | 0.0453815 | 0.4317077 | 0.7547301 | 1.8521804 | 12 | TTK;NDC80;NUF2;SKA3;SPC25;AURKB;PPP1CA;SKA2;SKA1;PPP1CB |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 0.0025466 | 0.0342685 | 0.4317077 | 0.6554122 | 1.8336222 | 20 | TLR2;TLR1;TNF;IL6;MYD88;TLR4;NFKBIA;MAP3K7;NFKB1;IRAK1;IKBKG |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 0.0016197 | 0.0250646 | 0.4550599 | 0.6241779 | 1.8313372 | 26 | STAT1;IFNG;IFNGR1;JAK3;IFNAR2;JAK2;STAT5A;STAT4;IFNGR2;STAT2 |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00498 | 0.0023327 | 0.0328174 | 0.4317077 | 0.8089039 | 1.8242734 | 8 | CCNE1;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0023863 | 0.0328255 | 0.4317077 | 0.5945871 | 1.8133752 | 30 | ARPC1B;ACTR3;ARPC5L;CYTH1;PIK3CG;CYTH4;ACTB;ACTR2;WASF3;ARPC2;ARPC5;PIK3CD;ARPC4;ACTG1;ABI1;ARF1;BRK1;ARPC1A |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0009687 | 0.0166558 | 0.4772708 | 0.6002173 | 1.8096207 | 29 | ARPC1B;ACTR3;NCKAP1L;ARPC5L;CYTH1;CYTH4;ACTB;ACTR2;WASF3;ARPC2;ARPC5;PIK3CD;ARPC4;ACTG1;ABI1;ARF1;BRK1;ARPC1A |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_P27_CELL_CYCLE_G1_S | 0.0015742 | 0.0250646 | 0.4550599 | 0.8468436 | 1.8093469 | 7 | CCNE1;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00536 | 0.0028333 | 0.0365383 | 0.4317077 | 0.7460610 | 1.8022391 | 11 | CDKN2A;CCNE1;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 0.0037390 | 0.0453815 | 0.4317077 | 0.6482438 | 1.7961963 | 19 | TUBB3;TUBB;TUBA4A;TUBB6;CENPE;CENPF;TUBA1C;TUBB2A;TUBA1A;BUB1B;TUBB4A |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00264 | 0.0040221 | 0.0478789 | 0.4070179 | 0.7330756 | 1.7708705 | 11 | CCNE1;CCNA2;E2F3;E2F1;E2F2;CCNE2;SKP2 |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00497 | 0.0074933 | 0.0724746 | 0.4070179 | 0.7587920 | 1.7689666 | 9 | CCNE1;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH | 0.0031931 | 0.0403377 | 0.4317077 | 0.8547111 | 1.7389316 | 6 | SERPING1;C1S;PLAU;C1R |
| KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0108257 | 0.0889991 | 0.3807304 | 0.7351271 | 1.7317255 | 10 | IL12RB2;JAK2;IL23A;STAT4;IL12RB1;STAT3;IL12A |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 0.0042861 | 0.0500588 | 0.4070179 | 0.6045064 | 1.7294682 | 22 | KIF2C;TUBB3;TUBB;TUBA4A;AURKA;TUBB6;TUBA1C;TUBB2A;AURKB;TUBA1A;TUBB4A;KIF18B;TUBA1B;MAPRE1 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 0.0065332 | 0.0702753 | 0.4070179 | 0.6180023 | 1.7289618 | 20 | PTPN7;DUSP6;DUSP2;DUSP4;DUSP10;MAPK1 |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 0.0022154 | 0.0318907 | 0.4317077 | 0.5734029 | 1.7287768 | 29 | ALYREF;NUP155;NUP93;NUP205;NXT2;NDC1;NUP88;SEH1L;NUP210;NXT1;NUP85;NUP214;SRSF3;NUP62;NCBP1 |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0088694 | 0.0797310 | 0.3807304 | 0.6512804 | 1.7274502 | 16 | STAT1;IFNG;IFNGR1;JAK2;IFNGR2;IL27;STAT3 |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 0.0070325 | 0.0705538 | 0.4070179 | 0.6149345 | 1.7203790 | 20 | TOP2A;KIF4A;DNMT3B;NCAPD2;NCAPG;SMC4;NCAPG2;NCAPH;PPP2R5D;PPP2R5C;NCAPD3;NCAPH2;SMC2 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 0.0072372 | 0.0711085 | 0.4070179 | 0.6598717 | 1.7195165 | 15 | CCNE1;E2F3;CKS1B;E2F1;E2F2;CCNE2;SKP2;CUL1 |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0087899 | 0.0797310 | 0.3807304 | 0.7609991 | 1.7162365 | 8 | PLCG2;SYK;LYN;BTK;BLNK;ITPR3 |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.0132091 | 0.1022054 | 0.3807304 | 0.6287865 | 1.7145680 | 17 | PLCG2;SYK;LYN;BTK;BLNK;CALM3;NFATC3 |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 0.0085953 | 0.0797310 | 0.3807304 | 0.6181705 | 1.7128673 | 19 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;PLK1;TUBB2A;TUBA1A;KIF2A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 0.0051184 | 0.0576049 | 0.4070179 | 0.5985214 | 1.7123455 | 22 | TUBB3;TUBB;TUBA4A;AURKA;TUBB6;TUBA1C;TUBB2A;TUBA1A;TACC3;TUBB4A;CLTA |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY | 0.0097401 | 0.0837377 | 0.3807304 | 0.6838430 | 1.7096982 | 13 | ARPC1B;ACTR3;ARPC5L;ACTB;ACTR2;ARPC2;ARPC5;ARPC4;ACTG1 |
| KEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS | 0.0178182 | 0.1212028 | 0.3524879 | 0.6955229 | 1.7068802 | 12 | IDO1;TDO2;KYNU;KMO;QPRT |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCNE_TO_CELL_CYCLE_G1_S | 0.0052732 | 0.0582881 | 0.4070179 | 0.8363290 | 1.7015328 | 6 | CCNE1;E2F3;E2F1;E2F2 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 0.0083641 | 0.0796520 | 0.3807304 | 0.6078340 | 1.7005143 | 20 | ARPC1B;ACTR3;ARPC5L;ACTB;ACTR2;WASF3;ARPC2;ARPC5;ARPC4;ACTG1;ABI1;BRK1;ARPC1A |
| KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.0106912 | 0.0889991 | 0.3807304 | 0.7932598 | 1.6948608 | 7 | C1QA;C1QB;C1QC;C2;C1S;C1R |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0070367 | 0.0705538 | 0.4070179 | 0.5765592 | 1.6837596 | 25 | ARPC1B;ACTR3;ARPC5L;CYTH1;CYTH4;ACTB;ACTR2;WASF3;ARPC2;ARPC5;ARPC4;ACTG1;ABI1;ARF1;BRK1;ARPC1A |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY | 0.0140161 | 0.1071111 | 0.3807304 | 0.6707386 | 1.6769357 | 13 | ARPC1B;ACTR3;ARPC5L;ACTB;ACTR2;ARPC2;ARPC5;ARPC4;ACTG1;ARPC1A;SRC |
| KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY | 0.0126204 | 0.1001541 | 0.3807304 | 0.7811585 | 1.6690055 | 7 | FASLG;MAP3K5;FAS;DAXX |
| KEGG_MEDICUS_VARIANT_LOSS_OF_CDKN1B_TO_P27_CELL_CYCLE_G1_S | 0.0146496 | 0.1092450 | 0.3807304 | 0.7372447 | 1.6626647 | 8 | CCNE1;E2F3;E2F1;E2F2;CCNE2 |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 0.0121001 | 0.0972719 | 0.3807304 | 0.5983783 | 1.6580256 | 19 | PLCG2;PRKCB;CXCR4;MAPK1;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 0.0168327 | 0.1170722 | 0.3524879 | 0.5884835 | 1.6566947 | 21 | WIPF1;ARPC1B;ACTR3;ARPC5L;NCK1;ACTB;ACTR2;ARPC2;ARPC5;NCK2;ARPC4;ACTG1;WIPF2;ARPC1A;EGFR;SRC |
| KEGG_MEDICUS_REFERENCE_MODIFYING_OF_CONDENSIN_II_SUBUNITS | 0.0101056 | 0.0856901 | 0.3807304 | 0.8126105 | 1.6532769 | 6 | CDK1;PLK1;AURKB;NCAPG2;NCAPD3;NCAPH2 |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY | 0.0167116 | 0.1170722 | 0.3524879 | 0.7323546 | 1.6516364 | 8 | PLCG2;PRKCB;EGFR;PLCG1 |
| KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY | 0.0109272 | 0.0889991 | 0.3807304 | 0.8083361 | 1.6445806 | 6 | CASP1;IL1B;IL18;NLRP3;PYCARD |
| KEGG_MEDICUS_REFERENCE_II_BLOOD_GROUP_ANTIGEN_BIOSYNTHESIS | 0.0158357 | 0.1126703 | 0.3524879 | 0.7675790 | 1.6399918 | 7 | B3GNT3;B4GALT3;GCNT2;B4GALT4;B3GNT4;B4GALT1 |
| KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY | 0.0158357 | 0.1126703 | 0.3524879 | 0.7673760 | 1.6395581 | 7 | CD40;RELB;CD40LG;TRAF2;NFKB2;TRAF3 |
| KEGG_MEDICUS_REFERENCE_P27_CELL_CYCLE_G1_S | 0.0173006 | 0.1189895 | 0.3524879 | 0.6444779 | 1.6328557 | 14 | CCNE1;CCNA2;E2F3;E2F1;E2F2;CCNE2;SKP2;CUL1 |
| KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 0.0199368 | 0.1326974 | 0.3524879 | 0.6405825 | 1.6229861 | 14 | CD19;SYK;LYN;CR2;PIK3CD |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 0.0288862 | 0.1788058 | 0.3524879 | 0.5898351 | 1.6083557 | 17 | TNF;IL6;MYD88;NFKBIA;MAP3K7;NFKB1;IRAK1;IKBKG;IL12A |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0233657 | 0.1522460 | 0.3524879 | 0.5716425 | 1.5992628 | 20 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A;ARHGEF2 |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0254899 | 0.1610027 | 0.3524879 | 0.6006153 | 1.5930667 | 16 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.0227804 | 0.1500116 | 0.3524879 | 0.7427375 | 1.5869161 | 7 | STAT1;ERBB2;VEGFA;STAT3;EGFR |
| KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0189900 | 0.1277698 | 0.3524879 | 0.7797620 | 1.5864459 | 6 | FUT3;FUT4;FUT7;ST3GAL6 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0352377 | 0.2117683 | 0.3217759 | 0.5791885 | 1.5793247 | 17 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 0.0157970 | 0.1126703 | 0.3524879 | 0.5377565 | 1.5777770 | 26 | CCL5;CCR5;PRKCB;GNGT2;GNB4;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M | 0.0552017 | 0.3163875 | 0.2820134 | 0.6664452 | 1.5699328 | 10 | CHEK1;CDK1;CDC25B;CCNB2;CHEK2;CCNB1;CDC25C |
| KEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY | 0.0327883 | 0.2009503 | 0.3217759 | 0.6138712 | 1.5553102 | 14 | FANCE;UBE2T;FANCA;FANCC;FANCG;FANCD2;FANCI;FANCB;ATR;FANCL;TOPBP1;UBB |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0617021 | 0.3440866 | 0.2663507 | 0.6841586 | 1.5429428 | 8 | BID;BAK1;CASP3;BAX;CASP8 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_REL_TO_TRANSCRIPTION | 0.0638298 | 0.3527736 | 0.2616635 | 0.6814666 | 1.5368716 | 8 | BIRC3;BCL2A1;CD40;TRAF1;CCND2 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0645161 | 0.3534114 | 0.2616635 | 0.6355323 | 1.5352378 | 11 | BID;FAS;BAK1;CASP3;APP;BAX |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN | 0.0721868 | 0.3732096 | 0.2450418 | 0.6501541 | 1.5315563 | 10 | FGG;FCN1;FCN3;FGB |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 0.0432918 | 0.2576695 | 0.3217759 | 0.5612541 | 1.5304215 | 17 | CCR5;PLCG2;CXCR4;CALM3;NFATC3 |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY | 0.0460312 | 0.2713649 | 0.3217759 | 0.6034428 | 1.5288887 | 14 | ARPC1B;ACTR3;ARPC5L;ACTB;ACTR2;ARPC2;ARPC5;ARPC4;ACTG1 |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 0.0338638 | 0.2055066 | 0.3217759 | 0.4935124 | 1.5051171 | 30 | CCL4;CCL2;CCL3;GNGT2;GNB4;PIK3CG |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 0.0602679 | 0.3391437 | 0.2765006 | 0.5515914 | 1.5040734 | 17 | IL1B;ZFP36;MYD88;MAP2K3;MAP3K7;IRAK1;IL1R1;MAP2K6;IL1RAP |
| KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY | 0.0765957 | 0.3854696 | 0.2377938 | 0.6665615 | 1.5032571 | 8 | FCGR3A;FCGR3B;RAC2;FCGR2A |
| KEGG_MEDICUS_REFERENCE_INACTIVATION_OF_CONDENSIN_I | 0.0728477 | 0.3732096 | 0.2489111 | 0.7373552 | 1.5001680 | 6 | NCAPD2;NCAPG;SMC4;NCAPH;CSNK2A2 |
| KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0704846 | 0.3729056 | 0.2529611 | 0.7628968 | 1.4928861 | 5 | FUT3;FUT4 |
| KEGG_MEDICUS_REFERENCE_MEVALONATE_PATHWAY | 0.0686695 | 0.3693549 | 0.2529611 | 0.6073636 | 1.4905287 | 12 | FDPS;IDI1;MVD;ACAT2;HMGCS1 |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION | 0.0995763 | 0.4634414 | 0.2065879 | 0.6329181 | 1.4755176 | 9 | IDH2;IDH1;IDH3G;ACLY;ACO2 |
| KEGG_MEDICUS_REFERENCE_NOD_NFKB_SIGNALING_PATHWAY | 0.1016949 | 0.4654772 | 0.2042948 | 0.6280862 | 1.4642531 | 9 | RIPK2;NOD2;NFKBIA;NFKB1;NOD1;IKBKG |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_INNER_KINETOCHORE | 0.0660793 | 0.3587990 | 0.2616635 | 0.5773948 | 1.4628931 | 14 | CENPW;CENPA;CENPN;CENPM;CENPO;CENPL;CENPI;CENPQ |
| KEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION | 0.0817204 | 0.4079431 | 0.2311267 | 0.6050808 | 1.4616771 | 11 | GZMB;HDAC2 |
| KEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0957447 | 0.4489845 | 0.2114002 | 0.6437705 | 1.4518577 | 8 | MMP9;CYBB;VCAM1;IL6;NFKB1 |
| KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 0.1101695 | 0.4802459 | 0.1957890 | 0.6213809 | 1.4486211 | 9 | PDCD1;CD274;PTPN6;PIK3CD;PDCD1LG2 |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.0727273 | 0.3732096 | 0.2529611 | 0.5100385 | 1.4358567 | 21 | CDC20;PTTG2;PTTG1;MAD2L1;MAD2L2;BUB1B |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_REPRESSION | 0.1236203 | 0.5135636 | 0.1882041 | 0.7029582 | 1.4301864 | 6 | MYCN;MAX |
| KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY | 0.0944206 | 0.4461554 | 0.2139279 | 0.5824475 | 1.4293823 | 12 | CCL2;BIRC3;NFKBIA;NFKB1;TNFRSF14;TRAF2;IKBKG |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.0890869 | 0.4342108 | 0.2249661 | 0.5381105 | 1.4272794 | 16 | CDC20;PTTG2;PTTG1 |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 0.0840909 | 0.4164182 | 0.2343926 | 0.5026724 | 1.4151197 | 21 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A;TUBA1B;MAPRE1 |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M | 0.1167728 | 0.4917169 | 0.1900233 | 0.5979491 | 1.4085780 | 10 | CHEK1;CDK1;CCNB2;CCNB1;CDC25C;ATR |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 0.1026201 | 0.4654772 | 0.2065879 | 0.5371692 | 1.3997741 | 15 | CDCA5;CDK1;PLK1;AURKB;PPP2R5D;PPP2R5C |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.1158798 | 0.4912987 | 0.1918922 | 0.5699544 | 1.3987229 | 12 | CCR5;CXCR4;PIK3CD |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 0.1093750 | 0.4802459 | 0.2020717 | 0.5115949 | 1.3950113 | 17 | TNF;MAPK1;IL6;APP;NFKB1;NRAS;RAF1 |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS | 0.1321586 | 0.5453744 | 0.1813831 | 0.7116664 | 1.3926352 | 5 | B3GNT5;FUT2 |
| KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S | 0.1412804 | 0.5605932 | 0.1752040 | 0.6843428 | 1.3923131 | 6 | E2F3;E2F1;E2F2;CDK6;CDK4 |
| KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.1490281 | 0.5765524 | 0.1682382 | 0.6498402 | 1.3884339 | 7 | STAT1;STAT5A;STAT3;EGFR |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA2_TO_RBP_JK_MEDIATED_TRANSCRIPTION | 0.1490281 | 0.5765524 | 0.1682382 | 0.6494323 | 1.3875624 | 7 | RUNX3;CR2 |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 0.1017699 | 0.4654772 | 0.2089550 | 0.4743751 | 1.3817570 | 24 | TNF;CREB3L2;ATF4;RPS6KA4;TRADD;CREB3L1;MAP2K3;MAP3K7;TRAF2;CREB5;RIPK1 |
| KEGG_MEDICUS_REFERENCE_AHR_SIGNALING_PATHWAY | 0.1404255 | 0.5605932 | 0.1723243 | 0.6084074 | 1.3721055 | 8 | VEGFA;IL6;CYP1B1;PTGS2 |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 0.0929204 | 0.4461554 | 0.2192503 | 0.4436972 | 1.3629924 | 31 | TUBB3;TPX2;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;HAUS8;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 0.1352550 | 0.5472081 | 0.1797823 | 0.4957405 | 1.3610333 | 18 | STAT1;IFNAR2;STAT2;IRF7 |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.1222222 | 0.5111862 | 0.1900233 | 0.4577796 | 1.3431248 | 26 | CCR5;CXCR4;RAC2;GNGT2;GNB4;CFL1;GNG5;PAK1;GNG7;GNG4;LIMK1 |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 0.1333333 | 0.5460159 | 0.1813831 | 0.4535242 | 1.3306395 | 26 | TUBB3;TPX2;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_E2_TO_NOD_NFKB_SIGNALING_PATHWAY | 0.1610169 | 0.5991851 | 0.1596467 | 0.5696234 | 1.3279592 | 9 | RIPK2;NFKBIA;NFKB1;NOD1;IKBKG;RELA;CDC42 |
| KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M | 0.1857451 | 0.6570071 | 0.1492075 | 0.6195533 | 1.3237235 | 7 | CHEK1;CDK1;CCNB2;CCNB1;WEE1;ATR |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_CELL_CYCLE_G1_S | 0.1942605 | 0.6680402 | 0.1473312 | 0.6464737 | 1.3152673 | 6 | E2F3;E2F1;E2F2;RBL1 |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE | 0.2030905 | 0.6869564 | 0.1437590 | 0.6399194 | 1.3019324 | 6 | FCN1;FCN3 |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.1466083 | 0.5765524 | 0.1709323 | 0.4348735 | 1.2979062 | 27 | STAT1;IL27RA;OSM;IL6;IL6R;JAK2;IL4R;IL27 |
| KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M | 0.1779661 | 0.6404710 | 0.1511488 | 0.5555380 | 1.2951219 | 9 | CHEK1;CDK1;CCNB2;CCNB1;CDKN1A;ATR |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 0.1603563 | 0.5991851 | 0.1644058 | 0.4867316 | 1.2910025 | 16 | TNF;MAPK1;IL6;NFKB1;NRAS;RAF1 |
| KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS | 0.1889597 | 0.6645797 | 0.1464162 | 0.5480195 | 1.2909595 | 10 | HSD17B2;SRD5A1 |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.1555556 | 0.5980676 | 0.1669338 | 0.4394821 | 1.2894399 | 26 | TLR2;MAPK1;MYD88;MAP2K3;TLR4;MAP3K7;MAPK13;IRAK1;FOS;MAP2K6;JUN;MAP2K2;MAPK14;MAP2K1 |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 0.1484716 | 0.5765524 | 0.1695706 | 0.4058685 | 1.2755903 | 33 | ARPC1B;ACTR3;ARPC5L;CLDN4;ACTB;ACTR2;CLDN1;ARPC2;ARPC5;CLDN10;CLDN14;ARPC4;ACTG1;CLDN7;CLDN23 |
| KEGG_MEDICUS_PATHOGEN_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_II | 0.2295806 | 0.7214767 | 0.1342735 | 0.6240480 | 1.2696417 | 6 | SDHA;GSTO1;SDHD;SDHC;SDHB |
| KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY | 0.2107527 | 0.6938389 | 0.1388051 | 0.5243684 | 1.2667023 | 11 | TRADD;NFKBIA;MAP3K7;NFKB1;IKBKG;RELA;TAB2 |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN | 0.2276596 | 0.7214767 | 0.1321473 | 0.5580158 | 1.2584603 | 8 | FCN1;FCN3 |
| KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY | 0.2229299 | 0.7149929 | 0.1335550 | 0.5298813 | 1.2482318 | 10 | PRKCB;PLCB4;PLCB2 |
| KEGG_MEDICUS_PATHOGEN_KSHV_K15_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.2340426 | 0.7280017 | 0.1301056 | 0.5525955 | 1.2462362 | 8 | NFKBIA;MAP3K7;NFKB1;TRAF2;IKBKG;RELA |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 0.2142857 | 0.6938389 | 0.1404062 | 0.4561014 | 1.2436923 | 17 | RFC4;FEN1;RFC2;PCNA;POLE3;POLE2;RFC3;LIG1;POLD1 |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2264574 | 0.7214767 | 0.1364904 | 0.4439196 | 1.2300414 | 19 | STAT1;IFNAR2;STAT2 |
| KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY | 0.2296137 | 0.7214767 | 0.1321473 | 0.4997722 | 1.2264891 | 12 | PRKCB;MAPK1;RAF1;FOS;JUN;MAP2K2;MAP2K1;PRKCA |
| KEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.1636727 | 0.6030558 | 0.1531588 | 0.9306965 | 1.2250901 | 1 | CCND2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE | 0.2617021 | 0.7534587 | 0.1221079 | 0.5360834 | 1.2089975 | 8 | MRAS;PPP1CA;RAF1;PPP1CB;PPP1CC |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.2146018 | 0.6938389 | 0.1395997 | 0.3925884 | 1.2059916 | 31 | CCL2;CCR2;GNGT2;GNB4;NFKBIA;PIK3CD;NFKB1;GNG5;IKBKG;GNG7;GNG4 |
| KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY | 0.2596567 | 0.7534259 | 0.1232572 | 0.4896067 | 1.2015419 | 12 | PRKCB;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 0.2388393 | 0.7355299 | 0.1321473 | 0.4406433 | 1.2015413 | 17 | CDC20;MAD2L1;TRIP13;BUB1B;CDC26;MAD2L1BP;CDC16 |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 0.2489083 | 0.7426450 | 0.1275053 | 0.4596291 | 1.1977173 | 15 | PRKD3;NFKBIA;NFKB1;PRKD2;IKBKG;PTPRJ;SRC;RELA |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 0.2845011 | 0.7861882 | 0.1162341 | 0.4935929 | 1.1627479 | 10 | BIRC5;PIK3CD;NFKB1;AKT1;RELA;MTOR |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.2863636 | 0.7878182 | 0.1204334 | 0.4115367 | 1.1585552 | 21 | PLCG2;CXCR4;PLCB4;PLCB2;CALM3;NFATC3 |
| KEGG_MEDICUS_REFERENCE_PKR_EIF2ALPHA_SIGNALING_PATHWAY | 0.3153348 | 0.8063275 | 0.1105647 | 0.5403079 | 1.1544095 | 7 | EIF2B3;EIF2S1;EIF2AK2;EIF2B5;EIF2B4;EIF2B1;EIF2B2 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.2819383 | 0.7861882 | 0.1193484 | 0.4554620 | 1.1539630 | 14 | PLCG2;CAMK1D;CAMK2D;PDGFRA;CALM3 |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR2_TO_CELL_SURFACE_MOLECULE_ENDOCYTOSIS | 0.3200883 | 0.8063275 | 0.1110115 | 0.5667052 | 1.1529764 | 6 | ICAM1;IFNGR1;CLEC2B |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY | 0.3063830 | 0.8063107 | 0.1114627 | 0.4585711 | 1.1464887 | 13 | MAPK1;YWHAQ;YWHAH;RAF1;YWHAZ;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_TMPRSS2_ERG_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.3174946 | 0.8063275 | 0.1101223 | 0.5364243 | 1.1461119 | 7 | MMP9;MMP3;PLAU;IL1R2 |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 0.3095768 | 0.8063275 | 0.1137873 | 0.4304914 | 1.1418315 | 16 | ST6GAL1;MGAT1;B4GALT3;MOGS;MAN1A1;GANAB;B4GALT1;B4GALT2 |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 0.3071749 | 0.8063107 | 0.1147507 | 0.4102191 | 1.1366621 | 19 | IL1B;MYD88;MAP3K7;IRAK1;IL1R1;FOS;IL1RAP;JUN |
| KEGG_MEDICUS_REFERENCE_OKAZAKI_FRAGMENT_MATURATION | 0.3204301 | 0.8063275 | 0.1092500 | 0.4701465 | 1.1357200 | 11 | FEN1;RNASEH2A;PCNA;DNA2;RNASEH2B;LIG1;POLD1 |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.3390558 | 0.8063275 | 0.1055209 | 0.4598625 | 1.1285468 | 12 | ERBB2;PIK3CD;EGFR;AKT1;RPS6KB2 |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 0.3022222 | 0.8063107 | 0.1152400 | 0.3907283 | 1.1253375 | 23 | PFKP;LDHC;LDHB;ENO1;PFKL;GAPDH;GPI;PKM;PGAM1;LDHA;PGK1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3258427 | 0.8063275 | 0.1110115 | 0.3911388 | 1.1190323 | 22 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;APP;TUBB4A;CAPN2 |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 0.3318486 | 0.8063275 | 0.1092500 | 0.4204765 | 1.1152682 | 16 | TNF;TRADD;NFKBIA;MAP3K7;NFKB1;TRAF2;IKBKG;RIPK1 |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 0.3311111 | 0.8063275 | 0.1092500 | 0.3815018 | 1.1141220 | 25 | EZH2;JARID2;HDAC2;TFDP1;EED;WDR5 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 0.3431818 | 0.8063275 | 0.1083943 | 0.3956943 | 1.1139558 | 21 | CHRM1;SLC25A5;ITPR3;PLCB4;PLCB2;APP |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.3269639 | 0.8063275 | 0.1071402 | 0.4712003 | 1.1099981 | 10 | C2;FCN1;FCN3 |
| KEGG_MEDICUS_REFERENCE_LIGHT_HVEM_NFKB_SIGNALING_PATHWAY | 0.3269639 | 0.8063275 | 0.1071402 | 0.4710055 | 1.1095390 | 10 | TNFSF14;NFKBIA;NFKB1;TNFRSF14;TRAF2;IKBKG |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS | 0.3465784 | 0.8063275 | 0.1059203 | 0.5432557 | 1.1052678 | 6 | B3GNT5;B4GALT3;B4GALT4;B4GALT1;B4GALT2 |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.3318584 | 0.8063275 | 0.1088201 | 0.3591626 | 1.1033109 | 31 | PRKCB;CXCR4;GNGT2;GNB4;PLCB4;PLCB2;PTK2B;GNG5 |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 0.3496659 | 0.8063275 | 0.1059203 | 0.4150318 | 1.1008265 | 16 | CDC20;PTTG1;CDC26;CDC16 |
| KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S | 0.3333333 | 0.8063275 | 0.1059203 | 0.4669913 | 1.1000829 | 10 | CDKN2A;E2F3;E2F1;CCND2;E2F2;CDK6;CCND3;CDK4 |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3525499 | 0.8063275 | 0.1051251 | 0.3968688 | 1.0895855 | 18 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 0.3595506 | 0.8063275 | 0.1047328 | 0.3893513 | 1.0892736 | 20 | CHRM1;SLC25A5;ITPR3;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 0.3571429 | 0.8063275 | 0.1047328 | 0.3987115 | 1.0872020 | 17 | TLR8;MYD88;IRF5;TLR9;IRAK1;TLR7 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.3656388 | 0.8063275 | 0.1024494 | 0.5544824 | 1.0850472 | 5 | CASP3;BAX;CYCS |
| KEGG_MEDICUS_VARIANT_DAB1_OVEREXPRESSION_TO_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.3601695 | 0.8063275 | 0.1009906 | 0.4641922 | 1.0821682 | 9 | VLDLR;PIK3CD;DAB1;AKT1 |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3636364 | 0.8063275 | 0.1031975 | 0.3934133 | 1.0800986 | 18 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_SECOND_CARBON_OXIDATION_2 | 0.3609342 | 0.8063275 | 0.1009906 | 0.4575436 | 1.0778272 | 10 | SDHA;FH;SDHD;SDHC;SUCLG1;SDHB;MDH1;MDH2 |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 0.3775281 | 0.8112004 | 0.1017139 | 0.3848295 | 1.0766231 | 20 | CREB3L2;MAPK1;ATF4;CREB3L1;NRAS;RAF1;CREB5 |
| KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 0.3686441 | 0.8063275 | 0.0995791 | 0.4611943 | 1.0751791 | 9 | ICOS;PIK3CD;ICOSLG;AKT1 |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 0.3658537 | 0.8063275 | 0.1028218 | 0.3913671 | 1.0744810 | 18 | GSTA5;GSTA2;GSTA1;GSTP1;MGST1;GSTA4;GSTO1 |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 0.3662921 | 0.8063275 | 0.1035763 | 0.3752305 | 1.0735192 | 22 | GSTA5;GSTA2;GSTA1;GSTP1;MGST1;GSTA4;GSTO1 |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.3752759 | 0.8093931 | 0.1009906 | 0.5274926 | 1.0731972 | 6 | HK3;BAX;HKDC1;HK2;HK1;VDAC1 |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 0.3666667 | 0.8063275 | 0.1028218 | 0.3713540 | 1.0695375 | 23 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.3714903 | 0.8068508 | 0.1002791 | 0.5005683 | 1.0695028 | 7 | NFKBIA;NFKB1;TRAF2;IKBKG;RELA |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY | 0.3813559 | 0.8112004 | 0.0975449 | 0.4583231 | 1.0684855 | 9 | E2F1;BIRC5;CDC25A;RAF1;CDC6;SRC |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.3711111 | 0.8068508 | 0.1020801 | 0.3627826 | 1.0644039 | 26 | CXCR4;RAC2;GNGT2;GNB4;CFL1;GNG5;PAK1;GNG7;GNG4;LIMK1 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.3805310 | 0.8112004 | 0.1002791 | 0.3636966 | 1.0593733 | 24 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY | 0.3892473 | 0.8167596 | 0.0972151 | 0.4383527 | 1.0589167 | 11 | PRKCB;PLCB4;PLCB2 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.4030837 | 0.8289329 | 0.0965630 | 0.4176699 | 1.0582125 | 14 | PLCG2;CAMK1D;CAMK2D;CALM3;EGFR;PLCG1 |
| KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 0.3914894 | 0.8186889 | 0.0962406 | 0.4230528 | 1.0576883 | 13 | LBR;DHCR7;SQLE;EBP;NSDHL;MSMO1 |
| KEGG_MEDICUS_REFERENCE_UREA_CYCLE | 0.3885210 | 0.8167596 | 0.0988903 | 0.5148830 | 1.0475427 | 6 | ASS1;ARG2 |
| KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.4148936 | 0.8389454 | 0.0928481 | 0.4143847 | 1.0360168 | 13 | PRKCB;ITPR3;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 0.4066667 | 0.8335320 | 0.0965630 | 0.3527216 | 1.0348848 | 26 | EXO1;RFC4;RFC2;PCNA;RPA2;POLE3;MSH2;POLE2;RFC3;LIG1;POLD1;MSH6;RPA1 |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 0.4133333 | 0.8388634 | 0.0956031 | 0.3584850 | 1.0324733 | 23 | GSTA5;GSTA2;GSTA1;GSTP1;MGST1;GSTA4;GSTO1 |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066 | 0.4340426 | 0.8527897 | 0.0902635 | 0.4096120 | 1.0240844 | 13 | CDKN2A;E2F3;E2F1;CCND2;E2F2;CDK6;CCND3;CDK4;CDKN1A |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY | 0.4172185 | 0.8389454 | 0.0946646 | 0.5018167 | 1.0209589 | 6 | MAP3K5;APP |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.4336283 | 0.8527897 | 0.0925529 | 0.3493802 | 1.0176724 | 24 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY | 0.4331210 | 0.8527897 | 0.0902635 | 0.4306302 | 1.0144278 | 10 | NFKBIA;MAP3K7;NFKB1;IKBKG;RELA;TLR3 |
| KEGG_MEDICUS_VARIANT_LOSS_OF_RASSF1_TO_RAS_RASSF1_SIGNALING_PATHWAY | 0.4392936 | 0.8527897 | 0.0916795 | 0.4954738 | 1.0080541 | 6 | RASSF5;NRAS;STK4;RASSF1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.4584270 | 0.8625115 | 0.0902635 | 0.3505396 | 1.0028795 | 22 | SLC25A5;ITPR3;PLCB4;PLCB2;CASP3;APP |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST | 0.4537634 | 0.8625115 | 0.0883594 | 0.4136038 | 0.9991312 | 11 | DDOST;RPN1;RPN2;STT3A;ALG6;STT3B |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_ | 0.4888393 | 0.8784637 | 0.0862866 | 0.5989211 | 0.9956931 | 3 | AMY1C;GAA |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 0.4576271 | 0.8625115 | 0.0870516 | 0.4248331 | 0.9904105 | 9 | CXCR4;ARHGEF1;GNA12;GNA13;ROCK2 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.4635762 | 0.8673890 | 0.0886261 | 0.4861294 | 0.9890427 | 6 | TCF7L1;TCF7 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.4733333 | 0.8694164 | 0.0878313 | 0.3373990 | 0.9853261 | 25 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN | 0.4801762 | 0.8716395 | 0.0865400 | 0.5017099 | 0.9817786 | 5 | CFH;CD55;CFI |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.4842342 | 0.8759869 | 0.0873098 | 0.3208366 | 0.9784894 | 30 | TUBB3;TUBB;TUBA4A;TUBB6;TUBA1C;TUBB2A;TUBA1A;TUBB4A |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.5152838 | 0.8860019 | 0.0822055 | 0.3739955 | 0.9745705 | 15 | PLCG2;CAMK1D;CAMK2D;CALM3;EGFR;PLCG1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.4787234 | 0.8715582 | 0.0847985 | 0.4306292 | 0.9711728 | 8 | PRKCB;PTK2B |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.4932432 | 0.8792614 | 0.0862866 | 0.3178782 | 0.9694667 | 30 | ITGB7;ITGB6;ACTB;ACTN1;ITGA4;ACTN4;ITGB4;ITGA9;ACTG1;ITGB8;VCL;FN1;ITGA5 |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 0.4966292 | 0.8792614 | 0.0857844 | 0.3457624 | 0.9673265 | 20 | EZH2;TRIM27;JARID2;EED |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.5078652 | 0.8830577 | 0.0845557 | 0.3370363 | 0.9642473 | 22 | SLC25A5;ITPR3;PLCB4;PLCB2;CASP3 |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION | 0.5042918 | 0.8814538 | 0.0824344 | 0.3926108 | 0.9635047 | 12 | CREB3L2;ATF4;CREB3L1;PCNA;CREB5 |
| KEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION | 0.5132159 | 0.8860019 | 0.0828962 | 0.4921467 | 0.9630647 | 5 | HEXA;GLB1;HEXB;GALNS |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 0.5278396 | 0.8891975 | 0.0819779 | 0.3619766 | 0.9601035 | 16 | TNF;TRADD;MAP3K7;TRAF2;RIPK1;FOS;JUN;TNFRSF1A |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 0.4910314 | 0.8784637 | 0.0862866 | 0.3462946 | 0.9595357 | 19 | WNT6;WNT10A;WNT2 |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.5286344 | 0.8891975 | 0.0813027 | 0.3749874 | 0.9500717 | 14 | PLCG2;PRKCB;MAPK1 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR | 0.4988962 | 0.8792614 | 0.0845557 | 0.4662027 | 0.9485014 | 6 | CFH;CFHR3 |
| KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION | 0.5055188 | 0.8814538 | 0.0838361 | 0.4639506 | 0.9439193 | 6 | CDCA5;STAG1 |
| KEGG_MEDICUS_REFERENCE_TLR4_IRF3_7_SIGNALING_PATHWAY | 0.5170213 | 0.8865268 | 0.0806388 | 0.4174607 | 0.9414746 | 8 | TLR4;IRF7;IRF3;TRAF3;IKBKE |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.5266667 | 0.8891975 | 0.0819779 | 0.3266498 | 0.9407849 | 23 | CREB3L2;CAMK1D;ATF4;CREB3L1;CAMK2D;CALM3;CREB5 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ANXA2_S100A10_REGULATED_ACTIN_CYTOSKELETON | 0.5396476 | 0.8979620 | 0.0802023 | 0.4787687 | 0.9368858 | 5 | ACTB;S100A10;ACTG1;ANXA2 |
| KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY | 0.5269978 | 0.8891975 | 0.0804200 | 0.4372275 | 0.9341703 | 7 | MAP3K5;TRAF2 |
| KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY | 0.5222930 | 0.8881851 | 0.0799859 | 0.3958293 | 0.9324479 | 10 | TNF;TRADD;CASP3;TRAF2;RIPK1;CASP8;TNFRSF1A |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.5550661 | 0.9091009 | 0.0787114 | 0.3653665 | 0.9256961 | 14 | PLCG2;PRKCB;MAPK1 |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS | 0.5548387 | 0.9091009 | 0.0774768 | 0.3818236 | 0.9223608 | 11 | ACSL1;ACSL5;ACSL4 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY | 0.5386313 | 0.8979620 | 0.0804200 | 0.4532362 | 0.9221206 | 6 | MAP3K5;DAXX |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION | 0.5430464 | 0.8987853 | 0.0799859 | 0.4525255 | 0.9206748 | 6 | MYCN;MAX |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_TP53_TO_TRANSCRIPTION | 0.5423729 | 0.8987853 | 0.0778840 | 0.3935376 | 0.9174514 | 9 | BAK1;GADD45A;BAX;CDKN1A;GADD45B |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 0.5812918 | 0.9274249 | 0.0768737 | 0.3407067 | 0.9036873 | 16 | ERBB2;MAPK1;NRAS;RAF1;EGFR;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 0.5829694 | 0.9274249 | 0.0756946 | 0.3458938 | 0.9013420 | 15 | PLCG2;PRKCB;MAPK1 |
| KEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING | 0.5695364 | 0.9274249 | 0.0774768 | 0.4420829 | 0.8994290 | 6 | MAPK1;RPS6KA3;RPS6KA1 |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 0.6017316 | 0.9335134 | 0.0736213 | 0.2974919 | 0.8984551 | 28 | WNT6;WNT10A;WNT2;SFRP1;TRABD2A |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_NFKB_SIGNALING_PATHWAY | 0.5761589 | 0.9274249 | 0.0768737 | 0.4410079 | 0.8972418 | 6 | NFKBIA;NFKB1;IKBKG;RELA |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY | 0.5787234 | 0.9274249 | 0.0747385 | 0.3965058 | 0.8942162 | 8 | MAP3K5;FOS;JUN |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050 | 0.5849890 | 0.9274249 | 0.0760837 | 0.4394159 | 0.8940029 | 6 | CASP3;BAX;CYCS |
| KEGG_MEDICUS_PATHOGEN_HIV_NEF_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.6035242 | 0.9339537 | 0.0743625 | 0.3518383 | 0.8914211 | 14 | TRADD;NFKBIA;MAP3K7;NFKB1;TRAF2;IKBKG;RIPK1 |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 0.6349558 | 0.9358038 | 0.0720033 | 0.2898083 | 0.8902614 | 31 | GNGT2;MAPK1;VEGFA;GNB4;HIF1A;GNG5;NRAS;RAF1;FOS;GNG7;GNG4 |
| KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.5916115 | 0.9285640 | 0.0755015 | 0.4371743 | 0.8894424 | 6 | MAP2K3;MAP2K6;MAP2K2;MAP2K1;MAP2K4 |
| KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY | 0.5826271 | 0.9274249 | 0.0741759 | 0.3812688 | 0.8888493 | 9 | VEGFA;HIF1A;TGFB1;TGFA |
| KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS | 0.5978723 | 0.9298567 | 0.0730744 | 0.3894809 | 0.8783734 | 8 | CSGALNACT1;CHPF2;CHST3 |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.6113537 | 0.9358038 | 0.0732559 | 0.3361825 | 0.8760359 | 15 | TRADD;NFKBIA;MAP3K7;NFKB1;TRAF2;IKBKG;RIPK1;TNFRSF1A;RELA |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 0.6319290 | 0.9358038 | 0.0723571 | 0.3175641 | 0.8718581 | 18 | CCT6A;CCT4;GAR1;CCT7;CCT3;TCP1;DKC1 |
| KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY | 0.6090713 | 0.9358038 | 0.0728939 | 0.4064736 | 0.8684622 | 7 | TNF;TRADD;TRAF2;RIPK1;TNFRSF1A |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 0.6170213 | 0.9358038 | 0.0714786 | 0.3837293 | 0.8654021 | 8 | PIK3CD;PDGFRA;AKT1;MTOR;PIK3CA;PIK3CB |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.6608315 | 0.9495815 | 0.0694481 | 0.2890093 | 0.8625656 | 27 | RASD1;POMC;CREB3L2;ADCY7;ATF4;CREB3L1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 0.6637555 | 0.9495815 | 0.0691198 | 0.2736993 | 0.8602002 | 33 | CREB3L2;GNGT2;GNB4;ATF4;CREB3L1;GNG5;MAPK13;CREB5;GNG7;GNG4 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 0.6284501 | 0.9358038 | 0.0704501 | 0.3649663 | 0.8597445 | 10 | SLC25A5;APP;CYCS;VDAC3;PPID |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 0.6473118 | 0.9472483 | 0.0696133 | 0.3545363 | 0.8564435 | 11 | RYR1;CALM3;CACNA1E;CACNA1A |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS | 0.6335541 | 0.9358038 | 0.0720033 | 0.4191139 | 0.8526981 | 6 | UGP2;GYG1;GYS1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.6846847 | 0.9647607 | 0.0691198 | 0.2783487 | 0.8489094 | 30 | GNGT2;GNB4;IL6;NFKBIA;PIK3CD;NFKB1;GNG5;IKBKG;GNG7;GNG4;AKT1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY | 0.6371490 | 0.9368058 | 0.0706196 | 0.3956393 | 0.8453139 | 7 | RAC2;SRC |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6726457 | 0.9536980 | 0.0697793 | 0.3041521 | 0.8427646 | 19 | SLC25A5;RYR1;ITPR3;CASP3 |
| KEGG_MEDICUS_VARIANT_EWSR1_WT1_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6578366 | 0.9495815 | 0.0701132 | 0.4111746 | 0.8365454 | 6 | IL2RB;MLF1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6888889 | 0.9667423 | 0.0681513 | 0.2901726 | 0.8357268 | 23 | SLC25A5;ITPR3;PLCB4;PLCB2;CASP3 |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 0.7218543 | 0.9738145 | 0.0655321 | 0.2674252 | 0.8265510 | 32 | CHRM1;GNGT2;GNB4;PIK3CG;LPAR3;GNG5;LPAR2;GNG7;GNG4;LPAR5;AKT1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.6732892 | 0.9536980 | 0.0689567 | 0.4054168 | 0.8248308 | 6 | PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_NOTCH_MESP2_SIGNALING | 0.6629956 | 0.9495815 | 0.0696133 | 0.4211036 | 0.8240430 | 5 | LFNG;EPHA4;RBPJ;TBX6;RIPPLY2 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.7120536 | 0.9735194 | 0.0667426 | 0.3016283 | 0.8224767 | 17 | CREB3L2;ATF4;CREB3L1;CREB5 |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.7380952 | 0.9738145 | 0.0635008 | 0.2693613 | 0.8134980 | 28 | CREB3L2;CAMK1D;ATF4;PLCB4;PLCB2;CREB3L1;CAMK2D;CALM3;CREB5 |
| KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY | 0.6857749 | 0.9647607 | 0.0661326 | 0.3450155 | 0.8127466 | 10 | MAPK1;RAF1;PAK1;MAP2K2;MAP2K1;CDC42 |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.7124464 | 0.9735194 | 0.0647943 | 0.3291072 | 0.8076608 | 12 | CXCR4;PIK3CD;AKT1;GNAI2 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6985138 | 0.9716405 | 0.0652353 | 0.3410323 | 0.8033635 | 10 | ITPR3;PLCB4;PLCB2;SPTBN2 |
| KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7106383 | 0.9735194 | 0.0645031 | 0.3561249 | 0.8031475 | 8 | PIK3CD;EGFR;AKT1;TGFA;PIK3CA;PIK3CB |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.7216036 | 0.9738145 | 0.0659816 | 0.3024584 | 0.8022381 | 16 | PLCG2;CALM3;NFATC3;EGFR;PLCG1 |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 0.7055085 | 0.9735194 | 0.0646485 | 0.3437683 | 0.8014247 | 9 | PIK3CD;EGFR;AKT1;MTOR;TGFA;PIK3CA;PIK3CB |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.7334802 | 0.9738145 | 0.0646485 | 0.3163060 | 0.8013961 | 14 | NFKBIA;PIK3CD;NFKB1;IKBKG;EGFR;AKT1;RELA |
| KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7070064 | 0.9735194 | 0.0646485 | 0.3386705 | 0.7978000 | 10 | PIK3CD;EGFR;AKT1;RPS6KB2;MTOR |
| KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS | 0.6926503 | 0.9667423 | 0.0679923 | 0.4357715 | 0.7973389 | 4 | HSD11B1;CBR1 |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7253219 | 0.9738145 | 0.0639272 | 0.3234180 | 0.7936990 | 12 | MAPK1;NRAS;RAF1;FOS;JUN;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION | 0.7297872 | 0.9738145 | 0.0632191 | 0.3170297 | 0.7926164 | 13 | CREB3L2;ATF4;CREB3L1;CREB5 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.7234043 | 0.9738145 | 0.0636424 | 0.3505784 | 0.7906389 | 8 | PIK3CD;EGFR;AKT1;MTOR;PIK3CA;PIK3CB |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.7351695 | 0.9738145 | 0.0626618 | 0.3355152 | 0.7821843 | 9 | MET;PIK3CD;AKT1;MTOR |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP | 0.7351695 | 0.9738145 | 0.0626618 | 0.3354151 | 0.7819509 | 9 | PNP;NT5C2;NT5E;LACC1 |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP | 0.7394068 | 0.9738145 | 0.0623861 | 0.3331794 | 0.7767388 | 9 | PNP;NT5C2;NT5E;LACC1 |
| KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY | 0.7278618 | 0.9738145 | 0.0640704 | 0.3628731 | 0.7753063 | 7 | JAK2;STAT5A |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.7572383 | 0.9799577 | 0.0636424 | 0.2916612 | 0.7735994 | 16 | CREB3L2;ATF4;CREB3L1;CREB5 |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 0.8187919 | 0.9971589 | 0.0601186 | 0.2338395 | 0.7719680 | 41 | TUBB3;TUBB;TUBA4A;TUBB6;RILP;TUBA1C;TUBB2A;TUBA1A;TUBB4A;ACTR1A;DYNLL2;DYNC1H1;TUBA1B |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.7483871 | 0.9752666 | 0.0625237 | 0.3166629 | 0.7649538 | 11 | PIK3CD;EGFR;AKT1;RPS6KB2;MTOR |
| KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 0.7638298 | 0.9799577 | 0.0610364 | 0.3057394 | 0.7643891 | 13 | LPAR3;LPAR2;ARHGEF1;LPAR5;GNA12;GNA13;ROCK2 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.7694013 | 0.9799577 | 0.0626618 | 0.2776995 | 0.7624116 | 18 | CREB3L2;ATF4;CREB3L1;CREB5 |
| KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY | 0.7596567 | 0.9799577 | 0.0617054 | 0.3099518 | 0.7606515 | 12 | VEGFA;HIF1A;CUL2;RBX1;TGFB1;TGFA |
| KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION | 0.7639485 | 0.9799577 | 0.0614364 | 0.3082462 | 0.7564659 | 12 | SEC13;PREB;SEC24A;SEC23B;SAR1A;SEC23A |
| KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY | 0.7885463 | 0.9882438 | 0.0611693 | 0.2984435 | 0.7561394 | 14 | SLC7A5;RRAGD |
| KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY | 0.7580994 | 0.9799577 | 0.0621124 | 0.3531429 | 0.7545172 | 7 | PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 0.7860262 | 0.9882438 | 0.0609039 | 0.2887880 | 0.7525336 | 15 | MYD88;TLR9;IRF7;IRAK1;TLR7 |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.7682119 | 0.9799577 | 0.0625237 | 0.3673958 | 0.7474762 | 6 | MAPK1;MAPK13;MAPK14 |
| KEGG_MEDICUS_VARIANT_EREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7876858 | 0.9882438 | 0.0594760 | 0.3166448 | 0.7459144 | 10 | PIK3CD;EGFR;AKT1;RPS6KB2 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GRM1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.7923729 | 0.9888686 | 0.0590955 | 0.3178933 | 0.7411026 | 9 | ITPR3;PLCB4;PLCB2 |
| KEGG_MEDICUS_VARIANT_DELETED_DMD_TO_DYSTROPHIN_ASSOCIATED_PROTEIN_COMPLEX | 0.7919321 | 0.9888686 | 0.0592219 | 0.3135174 | 0.7385473 | 10 | ACTB;ACTG1;SNTB1;DTNA |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY | 0.7832618 | 0.9882438 | 0.0602484 | 0.2996402 | 0.7353458 | 12 | TNF;NFKB1 |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 0.8488889 | 0.9993386 | 0.0580984 | 0.2549091 | 0.7341644 | 23 | GNGT2;GNB4;LPAR3;GNG5;LPAR2;GNG7;GNG4;LPAR5 |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 0.8013100 | 0.9929050 | 0.0599892 | 0.2811559 | 0.7326458 | 15 | MAPK1;PTK2B;NRAS;RAF1;SRC;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P53_MEDIATED_TRANSCRIPTION | 0.8025478 | 0.9929050 | 0.0585938 | 0.3107062 | 0.7319250 | 10 | BAK1;GADD45A;BAX;CDKN1A;GADD45B |
| KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8021505 | 0.9929050 | 0.0592219 | 0.3009819 | 0.7270738 | 11 | MAPK1;NRAS;RAF1;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.7995595 | 0.9929050 | 0.0605093 | 0.3711663 | 0.7263225 | 5 | FOS;JUN;MAPK10;MAPK8;MAPK9 |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.8622222 | 0.9993386 | 0.0573667 | 0.2472795 | 0.7255176 | 26 | PROM1;MEF2C;BMP2K |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.8100437 | 0.9929050 | 0.0594760 | 0.2771367 | 0.7221724 | 15 | VLDLR;PIK3CD;DAB1;RHEB;AKT1;RPS6KB2 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.8099352 | 0.9929050 | 0.0589694 | 0.3343786 | 0.7144256 | 7 | OPTN;FKBP8;FAF2;CISD2;HK1;CISD1;PINK1 |
| KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8237885 | 0.9971589 | 0.0590955 | 0.2813416 | 0.7128099 | 14 | MAPK1;MET;NRAS;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.8347458 | 0.9992073 | 0.0566484 | 0.3057178 | 0.7127177 | 9 | ACTB;ACTG1;VCL;ITGA5;TLN1;ITGB1 |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 0.8650442 | 0.9993386 | 0.0570060 | 0.2317188 | 0.7118164 | 31 | EZH2;JARID2;PHF19;CBX2;EED |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.8079470 | 0.9929050 | 0.0601186 | 0.3495759 | 0.7112211 | 6 | ATF4;PRNP;EIF2S1;EIF2AK3 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.8236559 | 0.9971589 | 0.0579755 | 0.2911877 | 0.7034142 | 11 | ITPR3;PLCB4;PLCB2 |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 0.8787879 | 0.9993386 | 0.0552496 | 0.2326329 | 0.7025747 | 28 | GNGT2;GNB4;IL6;PIK3CG;NFKB1;GNG5 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8507795 | 0.9993386 | 0.0580984 | 0.2630867 | 0.6978089 | 16 | SLC25A5;CASP3;CYCS;VDAC3;CASP7;PSEN1;VDAC2;RYR3;MCU;SLC25A6;APAF1;VDAC1;CASP9;SLC25A31;SLC25A4;PSEN2 |
| KEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX | 0.8361702 | 0.9992073 | 0.0567672 | 0.3079974 | 0.6946084 | 8 | SMC6;RAD18;RNF168;UBB |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048 | 0.8293737 | 0.9982176 | 0.0578530 | 0.3242303 | 0.6927432 | 7 | CASP3;HTRA2;CYCS;APAF1;CASP9;PINK1;TRAP1 |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA1_TO_P53_MEDIATED_TRANSCRIPTION | 0.8513800 | 0.9993386 | 0.0558265 | 0.2900987 | 0.6833803 | 10 | BAK1;GADD45A;BAX;CDKN1A;GADD45B |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 0.8444924 | 0.9993386 | 0.0570060 | 0.3165906 | 0.6764204 | 7 | AKT1;RPS6KB2;MTOR;PIK3CA |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8722467 | 0.9993386 | 0.0564118 | 0.2640037 | 0.6688824 | 14 | MAPK1;NRAS;PDGFRA;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 0.8680851 | 0.9993386 | 0.0550211 | 0.2635320 | 0.6588650 | 13 | SLC25A5;ITPR3;SIGMAR1 |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_PI3K_SIGNALING_PATHWAY | 0.8832272 | 0.9993386 | 0.0541201 | 0.2770276 | 0.6525888 | 10 | ADRB2;PIK3CD;AKT1;GNAI2 |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 0.9125561 | 0.9993386 | 0.0551352 | 0.2354820 | 0.6524890 | 19 | IFIH1;TANK;IRF7;IRF3;TBKBP1;TRAF3;IKBKE |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.9090909 | 0.9993386 | 0.0547940 | 0.2369248 | 0.6504664 | 18 | PLCB4;PLCB2;CALM3;PTGS2;NFATC3 |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 0.8807947 | 0.9993386 | 0.0560596 | 0.3165726 | 0.6440751 | 6 | PIK3CD;AKT1;PIK3CA;PIK3CB |
| KEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY | 0.8854626 | 0.9993386 | 0.0557104 | 0.3278408 | 0.6415402 | 5 | E2F1;RAF1;SRC |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.8872340 | 0.9993386 | 0.0540088 | 0.2557195 | 0.6393327 | 13 | SLC25A5;CASP3 |
| KEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION | 0.9023355 | 0.9993386 | 0.0531298 | 0.2710147 | 0.6384245 | 10 | DNMT3B;DNMT3A;DNMT1;MAT2B |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8893617 | 0.9993386 | 0.0538979 | 0.2543933 | 0.6360171 | 13 | SLC25A5;ITPR3 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_ITPR1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.8898488 | 0.9993386 | 0.0545681 | 0.2921681 | 0.6242398 | 7 | PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE | 0.9108280 | 0.9993386 | 0.0526973 | 0.2648686 | 0.6239461 | 10 | CALM3;TFEB;PPP3CC;PPP3R1;MCOLN1;CALM2;PPP3R2;CALM1;PPP3CA;PPP3CB |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9379157 | 0.9993386 | 0.0533478 | 0.2259726 | 0.6203976 | 18 | SLC25A5;PLCB4;PLCB2 |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 0.9279476 | 0.9993386 | 0.0531298 | 0.2375910 | 0.6191227 | 15 | MAPK1;MET;NRAS;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 0.9422222 | 0.9993386 | 0.0532386 | 0.2142794 | 0.6171467 | 23 | KDELR3;COPB2;KDELR2;COPG1;ARF1;COPE;ARCN1;GBF1;TMED5;TMED3;TMED9 |
| KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY | 0.9194915 | 0.9993386 | 0.0521630 | 0.2610902 | 0.6086778 | 9 | SLC16A10;SLC16A2;RXRB;THRB;ATP2A2;RXRG;MYH6;THRA |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.9194915 | 0.9993386 | 0.0521630 | 0.2607231 | 0.6078221 | 9 | MET;PIK3CD;AKT1 |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 0.9344978 | 0.9993386 | 0.0528050 | 0.2316393 | 0.6036137 | 15 | MAPK1;FLT3LG;NRAS;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9191489 | 0.9993386 | 0.0523759 | 0.2671175 | 0.6024144 | 8 | MAPK1;GNAI2 |
| KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY | 0.9214437 | 0.9993386 | 0.0521630 | 0.2554459 | 0.6017493 | 10 | MAPK1;RAF1;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.9204301 | 0.9993386 | 0.0528050 | 0.2470024 | 0.5966770 | 11 | PIK3CD;CBL;AKT1 |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY | 0.9268817 | 0.9993386 | 0.0524828 | 0.2439619 | 0.5893321 | 11 | RASSF5;NRAS;STK4;EGFR;GRB2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_SPRED_AND_NF1 | 0.9249448 | 0.9993386 | 0.0537873 | 0.2862206 | 0.5823233 | 6 | SPRED1;NRAS |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9603524 | 0.9993386 | 0.0519512 | 0.2275061 | 0.5764118 | 14 | MAPK1;NRAS;RAF1;EGFR;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9406780 | 0.9993386 | 0.0511148 | 0.2466566 | 0.5750289 | 9 | MAPK1;GNAI2 |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 0.9595506 | 0.9993386 | 0.0529130 | 0.2007292 | 0.5742781 | 22 | CTLA4;PPP2R2B;CD80;PPP2R5D;PPP2R5C;PPP2R3C;PPP2R3A |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9340426 | 0.9993386 | 0.0516356 | 0.2529115 | 0.5703764 | 8 | MAPK1;GNAI2 |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9585153 | 0.9993386 | 0.0516356 | 0.2188402 | 0.5702614 | 15 | MAPK1;NRAS;RAF1;EGFR;GRB2;MAP2K2;MAP2K1;TGFA |
| KEGG_MEDICUS_REFERENCE_V_D_J_RECOMBINATION | 0.9420601 | 0.9993386 | 0.0516356 | 0.2321072 | 0.5696135 | 12 | XRCC6;XRCC5;DCLRE1C;PRKDC;XRCC4;NHEJ1;LIG4;POLL;RAG2;DNTT;POLM;RAG1 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.9361702 | 0.9993386 | 0.0515309 | 0.2521055 | 0.5685588 | 8 | PIK3CD;EGFR;AKT1 |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_GLC_6P_TO_MAN_P_DOL | 0.9449153 | 0.9993386 | 0.0509083 | 0.2437488 | 0.5682500 | 9 | GPI;GMPPB;DPM1;PMM2;PMM1 |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.9553191 | 0.9993386 | 0.0506004 | 0.2451725 | 0.5529232 | 8 | PIK3CD;EGFR;AKT1 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 0.9597458 | 0.9993386 | 0.0501934 | 0.2328658 | 0.5428784 | 9 | PIK3CD;NRAS;AKT1 |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9801762 | 0.9993386 | 0.0510114 | 0.2123566 | 0.5380287 | 14 | MAPK1;NRAS;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9759825 | 0.9993386 | 0.0508054 | 0.2044436 | 0.5327463 | 15 | MAPK1;NRAS;RAF1;EGFR;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.9702128 | 0.9993386 | 0.0498907 | 0.2328525 | 0.5251386 | 8 | PIK3CD;AKT1;PIK3CA;PIK3CB |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL | 0.9569892 | 0.9993386 | 0.0510114 | 0.2167242 | 0.5235347 | 11 | P2RX5;GRIN2D;P2RX7;P2RX3 |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9825328 | 0.9993386 | 0.0504983 | 0.2001052 | 0.5214410 | 15 | MAPK1;NRAS;RAF1;SRC;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 0.9847162 | 0.9993386 | 0.0503964 | 0.1979478 | 0.5158193 | 15 | SLC25A5;APP;GRIN2D |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55 | 0.9691630 | 0.9993386 | 0.0515309 | 0.2602870 | 0.5093466 | 5 | GORASP2;MAP1LC3B;LAMP2 |
| KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY | 0.9745763 | 0.9993386 | 0.0494905 | 0.2176924 | 0.5075047 | 9 | LPAR3;LPAR2;LPAR5 |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 0.9677419 | 0.9993386 | 0.0504983 | 0.2086844 | 0.5041132 | 11 | ADRB2;PIK3CD;AKT1;GNAI2 |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 0.9745763 | 0.9993386 | 0.0494905 | 0.2131372 | 0.4968853 | 9 | PIK3CD;EGFR;AKT1 |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27 | 0.9720430 | 0.9993386 | 0.0502948 | 0.2043834 | 0.4937234 | 11 | TEX10;DCAF7 |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9912664 | 0.9993386 | 0.0500923 | 0.1851025 | 0.4823464 | 15 | MAPK1;NRAS;RAF1;EGFR;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9911894 | 0.9993386 | 0.0504983 | 0.1856630 | 0.4703976 | 14 | MAPK1;NRAS;RAF1;GRB2;MAP2K2;MAP2K1 |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 0.9800443 | 0.9993386 | 0.0513223 | 0.1706198 | 0.4684292 | 18 | SLC25A5;CASP3;GRIN2D;PRNP |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 0.9978022 | 0.9994168 | 0.0500923 | 0.1477309 | 0.4660515 | 34 | RPS7;RPS12;RPS19;RPS10;RPS16;RPS25;RPS6;RPS27A;RPS18;RPSA;FAU;RPS20;RPS27;RPS17;RPS21;RPS8;RPS3;RPS11;RPS28;RPS3A;RPS4X;RPS24;RPS4Y1;RPS4Y2;RPS29;RPS2;RPS26;RPS15A;RPS5;RPS9;RPS13;RPS15 |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 0.9934498 | 0.9994168 | 0.0499914 | 0.1753936 | 0.4570466 | 15 | PIK3CD;FLT3LG;NRAS;AKT1;GRB2 |
| KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 0.9957537 | 0.9994168 | 0.0486034 | 0.1912923 | 0.4506238 | 10 | MET;PIK3CD;AKT1 |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 0.9911308 | 0.9993386 | 0.0508054 | 0.1538593 | 0.4224139 | 18 | TANK;IRF7;IRF3;TBKBP1;TRAF3;IKBKE |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 0.9963834 | 0.9994168 | 0.0412376 | -0.1530221 | -0.3985950 | 16 | IKBKB;IFNA6;MAVS;IFNA8;IFNA2;IFNA16;IFNA21;IFNA5;IFNA4;IFNA10 |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 1.0000000 | 1.0000000 | 0.0405756 | -0.1088973 | -0.4052601 | 81 | RPS23;RPL22;RPL9;RPS14;RPL41;RPL29;RPL28;RPL8;RPL13A;RPL14;RPS15;RPS13;RPS9;RPS5;RPLP1;RPS15A;RPS26;RPL37A;RPL31;RPS2;RPS29;RPL12;RPL18;RPS4Y2;RPS4Y1;RPS24;RPLP0;RPL36;RPS4X;RPL38;RPL13;RPL11;RPL27A;RPL34;RPL30;RPS3A;RPL37;RPS28;RPL15;RPLP2;RPL17;RPS11;RPL26;RPS3;RPS8;RPL36A;RPS21;RPS17;RPL10A;RPS27;RPS20;FAU;RPL6;RPL10;RPL3;RPL27;RPL5;RPL32;RPL7;RPL4;RPSA;RPL7A;RPL23A;RPS18;RPL39;RPL21;RPS27A;RPL24;RPL35A;RPS6;RPL35;UBA52;RPS25;RPL23;RPL18A;RPS16;RPS10;RPS19;RPS12;RPS7;RPL19 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION | 0.9906716 | 0.9993386 | 0.0429311 | -0.1797884 | -0.4362916 | 12 | ATG4D |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_BIFUNCTIONAL_GLYCOSYLASE | 0.9849624 | 0.9993386 | 0.0435378 | -0.2097602 | -0.4510223 | 8 | NTHL1 |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9871324 | 0.9993386 | 0.0424170 | -0.1833773 | -0.4709752 | 15 | MAPK3;SOS2;EGF;HRAS |
| KEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS | 0.9813780 | 0.9993386 | 0.0432769 | -0.1995148 | -0.4743741 | 11 | GPX4;GCLM;GPX6;GCLC;GSS |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION | 0.9799636 | 0.9993386 | 0.0423318 | -0.2501954 | -0.4903024 | 6 | SHARPIN |
| KEGG_MEDICUS_REFERENCE_DNA_DEGRADATION_BY_EXTRACELLULAR_ENDOLYSOSOMAL_DNASE | 0.9777365 | 0.9993386 | 0.0432769 | -0.2399103 | -0.4961157 | 7 | DNASE1L2;DNASE1;DNASE2B |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 0.9708029 | 0.9993386 | 0.0428451 | -0.1990177 | -0.5058843 | 14 | CACNA1D |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 0.9567669 | 0.9993386 | 0.0448645 | -0.2367338 | -0.5090203 | 8 | BAD;AKT2;KIT;AKT3 |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 0.9802158 | 0.9993386 | 0.0417397 | -0.1906914 | -0.5114935 | 19 | PPP2R2C;PPP2R5A;PPP2CA;PPP2R2A;AKT2;PPP2CB;PPP2R3B;PPP2R2D |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9635036 | 0.9993386 | 0.0431902 | -0.2047969 | -0.5205744 | 14 | MAPK3;SOS2;FLT3;HRAS |
| KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2 | 0.9552239 | 0.9993386 | 0.0445962 | -0.2155590 | -0.5230960 | 12 | PCGF3;PCGF5;YAF2;RYBP |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY | 0.9553073 | 0.9993386 | 0.0445071 | -0.2241286 | -0.5328969 | 11 | ACVR2B;BMPR2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP | 0.9436090 | 0.9993386 | 0.0454968 | -0.2516929 | -0.5411850 | 8 | RASA4;RASA1 |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 0.9692586 | 0.9993386 | 0.0425023 | -0.2102297 | -0.5476104 | 16 | PPP2R2C;PPP2R5A;PPP2CA;PPP2R2A;PPP2CB;PPP2R3B;PPP2R2D |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381 | 0.9440299 | 0.9993386 | 0.0451344 | -0.2280756 | -0.5534698 | 12 | HEY1;NOTCH4;NOTCH3;MAML3;HES1;RBPJL |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.9508197 | 0.9993386 | 0.0437126 | -0.2834597 | -0.5554898 | 6 | HSPA5;SOD1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9577206 | 0.9993386 | 0.0438002 | -0.2163281 | -0.5556043 | 15 | PDGFRB;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY | 0.9360902 | 0.9993386 | 0.0458620 | -0.2620198 | -0.5633898 | 8 | NQO1 |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY | 0.9416058 | 0.9993386 | 0.0442407 | -0.2241432 | -0.5697509 | 14 | TBK1;IFNA6;IFNA8;IFNA2;IFNA16;IFNA21;IFNA5;IFNA4;IFNA10 |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 0.9448529 | 0.9993386 | 0.0444181 | -0.2246593 | -0.5770016 | 15 | SOS2;EGF;BAD;HRAS;AKT2;KRAS |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CN_SIGNALING_PATHWAY | 0.9365672 | 0.9993386 | 0.0454968 | -0.2382683 | -0.5782043 | 12 | NFATC4;PPP3CB;PPP3CA |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 0.9568345 | 0.9993386 | 0.0428451 | -0.2185701 | -0.5862728 | 19 | GRIN2C;HTT |
| KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION | 0.9199255 | 0.9993386 | 0.0462303 | -0.2484546 | -0.5907353 | 11 | NOTCH4;PSEN2;APH1B;NOTCH3 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9319853 | 0.9993386 | 0.0450443 | -0.2311817 | -0.5937533 | 15 | FGFR1;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9154412 | 0.9993386 | 0.0458620 | -0.2370359 | -0.6087888 | 15 | FGFR1;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_REFERENCE_HEME_BIOSYNTHESIS | 0.8943396 | 0.9993386 | 0.0481184 | -0.2770267 | -0.6158937 | 9 | ALAD;FECH;UROD |
| KEGG_MEDICUS_REFERENCE_HYDROLYSIS_OF_SPHINGOMYELIN | 0.9090909 | 0.9993386 | 0.0466015 | -0.2999567 | -0.6202871 | 7 | ASAH1;SMPD4;SMPD3;SMPD1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.9107468 | 0.9993386 | 0.0456790 | -0.3165967 | -0.6204277 | 6 | SNCA;HSPA5 |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG7_TO_ALG11 | 0.9107468 | 0.9993386 | 0.0456790 | -0.3177856 | -0.6227576 | 6 | ALG1;ALG13 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION | 0.8998145 | 0.9993386 | 0.0470700 | -0.3048556 | -0.6304176 | 7 | HTT;BDNF |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1 | 0.8888889 | 0.9993386 | 0.0483118 | -0.2742776 | -0.6311788 | 10 | ATG14;BECN1;WIPI2;PIK3C3 |
| KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING | 0.8947368 | 0.9993386 | 0.0479259 | -0.2595805 | -0.6361292 | 13 | PAXIP1;TP53BP1;POLM;DNTT;POLL |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.9236364 | 0.9993386 | 0.0449543 | -0.2242064 | -0.6387144 | 24 | GNG11;GNG12;GNG13;GNG3;GNB5;PIK3R5;GNG10;GNGT1 |
| KEGG_MEDICUS_REFERENCE_C9ORF72_MEDIATED_AUTOPHAGY_INITIATION | 0.8701299 | 0.9993386 | 0.0486034 | -0.3120631 | -0.6453221 | 7 | SMCR8 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2 | 0.8850365 | 0.9993386 | 0.0470700 | -0.3526674 | -0.6539026 | 5 | UVRAG;BECN1 |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 0.8978102 | 0.9993386 | 0.0464155 | -0.2576437 | -0.6549061 | 14 | SOS2;FLT3;BAD;HRAS;AKT2;KRAS |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 0.8965517 | 0.9993386 | 0.0462303 | -0.2487673 | -0.6608593 | 18 | CAMK2B |
| KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 0.8528302 | 0.9993386 | 0.0502948 | -0.2992362 | -0.6652705 | 9 | PAQR5 |
| KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.8850365 | 0.9993386 | 0.0470700 | -0.2648076 | -0.6731160 | 14 | NBR1;MAP1LC3A;PINK1;MAP1LC3C;CALCOCO2;CISD1;HK1;CISD2;TAX1BP1;FAF2 |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_NEIL_GLYCOSYLASE | 0.8320755 | 0.9982176 | 0.0514265 | -0.3060948 | -0.6805186 | 9 | NEIL1;NEIL2;PNKP;POLB |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.8647687 | 0.9993386 | 0.0469759 | -0.2536553 | -0.7025230 | 21 | CGA |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 0.8816029 | 0.9993386 | 0.0471642 | -0.2285502 | -0.7100805 | 32 | RPA4;BRCA1;POLK;POLD4 |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 0.8264014 | 0.9971589 | 0.0497903 | -0.2763206 | -0.7197653 | 16 | TERF1;RTEL1;NHP2;CTC1 |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8143382 | 0.9961964 | 0.0512184 | -0.2816720 | -0.7234295 | 15 | AREG;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.7871940 | 0.9882438 | 0.0538979 | -0.3153364 | -0.7256650 | 10 | MAP1LC3A;PINK1;MAP1LC3C;CISD1;HK1;CISD2;FAF2;SQSTM1 |
| KEGG_MEDICUS_REFERENCE_GLUCONEOGENESIS | 0.8321168 | 0.9982176 | 0.0498907 | -0.3918534 | -0.7265597 | 5 | PCK1 |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_POMT_TO_POMK | 0.8229927 | 0.9971589 | 0.0503964 | -0.3945195 | -0.7315032 | 5 | POMT2 |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.8260870 | 0.9971589 | 0.0498907 | -0.2525701 | -0.7323281 | 25 | GNG11;GNG12;GNG13;GNG3;GNB5;CXCR2;PIK3R5;GNG10;GNGT1 |
| KEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.7886792 | 0.9882438 | 0.0538979 | -0.3304535 | -0.7346735 | 9 | NBR1;TBK1;MAP1LC3A |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8050542 | 0.9929050 | 0.0509083 | -0.2795017 | -0.7349737 | 17 | PDGFA;PDGFRB;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8083183 | 0.9929050 | 0.0508054 | -0.2840923 | -0.7400091 | 16 | FGFR3;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY | 0.7672253 | 0.9799577 | 0.0545681 | -0.3143940 | -0.7475155 | 11 | RALGDS;SOS2;EGF;HRAS |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY | 0.7744361 | 0.9823277 | 0.0545681 | -0.3059710 | -0.7498139 | 13 | MAP3K1;SOS2;EGF;HRAS;KRAS;MAPK9 |
| KEGG_MEDICUS_REFERENCE_STRAD_STK11_TSC_SIGNALING_PATHWAY | 0.7725564 | 0.9819557 | 0.0546808 | -0.3495150 | -0.7515202 | 8 | PRKAA2;TSC2;TSC1;STRADB;STK11 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR | 0.7650376 | 0.9799577 | 0.0551352 | -0.3085331 | -0.7560925 | 13 | WDFY3;NBR1 |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_MONOFUNCTIONAL_GLYCOSYLASE | 0.7631579 | 0.9799577 | 0.0552496 | -0.3524676 | -0.7578687 | 8 | MPG;SMUG1;POLB |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 0.8224638 | 0.9971589 | 0.0500923 | -0.2573893 | -0.7584725 | 26 | GNG11;MAPK3;GNG12;GNG13;GNG3;GNB5;CXCR2;HRAS;GNG10;GNGT1 |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST | 0.7462406 | 0.9752666 | 0.0562941 | -0.3175734 | -0.7782468 | 13 | CHRD;GREM2;BMP4;GDF6 |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 0.7472924 | 0.9752666 | 0.0543434 | -0.2978199 | -0.7831431 | 17 | GHR;LEP;PRLR;LEPR;EPOR |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 0.7175141 | 0.9738145 | 0.0582216 | -0.3403689 | -0.7832710 | 10 | CD86 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 0.7312030 | 0.9738145 | 0.0572461 | -0.3654892 | -0.7858675 | 8 | PLN;MLN;ATP2A1;ATP2A2 |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 0.7590580 | 0.9799577 | 0.0537873 | -0.2798442 | -0.7861108 | 23 | ITGA3;ITGA7;ITGB3;ITGA10;ARHGAP35;ITGA2;ITGB5 |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 0.7426471 | 0.9752350 | 0.0554793 | -0.3084716 | -0.7922600 | 15 | KITLG;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.7349624 | 0.9738145 | 0.0570060 | -0.3256243 | -0.7979763 | 13 | IL20;IL20RA;IL24 |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.7391304 | 0.9738145 | 0.0550211 | -0.2848334 | -0.8001260 | 23 | PTK2;ITGA3;ITGA7;ITGB3;ITGA10;ITGA2;ITGB5 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7436364 | 0.9752350 | 0.0549074 | -0.2824396 | -0.8046076 | 24 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1 |
| KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.7201493 | 0.9738145 | 0.0576091 | -0.3323496 | -0.8065110 | 12 | TRH |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7302752 | 0.9738145 | 0.0561767 | -0.2749665 | -0.8163250 | 27 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1;CRH |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7101449 | 0.9735194 | 0.0568864 | -0.2805670 | -0.8267724 | 26 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1;CRH |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 0.7101449 | 0.9735194 | 0.0568864 | -0.2806520 | -0.8270229 | 26 | PTK2;ITGA3;ITGA7;ITGB3;ITGA10;ITGA2;ITGB5 |
| KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION | 0.6934307 | 0.9667423 | 0.0583453 | -0.3266308 | -0.8302649 | 14 | FAN1;SLX4 |
| KEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM | 0.7080292 | 0.9735194 | 0.0573667 | -0.4500675 | -0.8344981 | 5 | MAOA;MAOB;TPH1 |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 0.6810036 | 0.9624229 | 0.0583453 | -0.2726115 | -0.8409210 | 30 | DOCK1;PTK2;ITGA3;ITGA7;ITGB3;ITGA10;ITGA2;ITGB5 |
| KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY | 0.6603774 | 0.9495815 | 0.0622490 | -0.3788034 | -0.8421665 | 9 | BMPR2;SMAD5;SMAD1;BMP10;SMAD4 |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 0.6925926 | 0.9667423 | 0.0590955 | -0.2813443 | -0.8427602 | 28 | DOCK1;ELMO3;ITGA3;ITGA7;ITGB3;ITGA10;ITGA2;ITGB5 |
| KEGG_MEDICUS_REFERENCE_TRAPPI_RAB1_SIGNALING_PATHWAY | 0.6603774 | 0.9495815 | 0.0622490 | -0.3791450 | -0.8429261 | 9 | TRAPPC6A;TRAPPC2;TRAPPC5 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S | 0.6679104 | 0.9504289 | 0.0611693 | -0.3482709 | -0.8451472 | 12 | CCND1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.6672932 | 0.9504289 | 0.0615707 | -0.3932561 | -0.8455714 | 8 | BCL2 |
| KEGG_MEDICUS_REFERENCE_DOUBLE_STRAND_BREAK_SIGNALING | 0.6554935 | 0.9495815 | 0.0619763 | -0.3570565 | -0.8489514 | 11 | RAD50;HERC2;UBE2N |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6642468 | 0.9495815 | 0.0601186 | -0.3196316 | -0.8491129 | 18 | BCL2;MAPK3;HRAS;CHRNB2;CHRNA3;CHRNB4;KRAS;CHRNA4 |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.6606498 | 0.9495815 | 0.0601186 | -0.3237251 | -0.8512630 | 17 | CAMK2B;PDGFA;PDGFRB |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.6612319 | 0.9495815 | 0.0602484 | -0.2899377 | -0.8543860 | 26 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1;GNAO1;GNAI1 |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 0.6469534 | 0.9472483 | 0.0607719 | -0.2809821 | -0.8667419 | 30 | DYNLRB2;DCTN4;DYNC2H1;DYNLT3;DYNC2LI1;DYNLRB1;DYNC1I2;ACTR10;DYNC1LI1 |
| KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY | 0.6308851 | 0.9358038 | 0.0643583 | -0.3778938 | -0.8696248 | 10 | MAP3K12;MAP3K10 |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 0.6333333 | 0.9358038 | 0.0633597 | -0.2907056 | -0.8708019 | 28 | RPA4;POLK;XPA;POLD4;GTF2H5 |
| KEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION | 0.6238361 | 0.9358038 | 0.0643583 | -0.3673234 | -0.8733624 | 11 | RPA4 |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 0.6337522 | 0.9358038 | 0.0618406 | -0.2888489 | -0.8767010 | 29 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6139706 | 0.9358038 | 0.0645031 | -0.3416333 | -0.8774306 | 15 | FGFR2;FGFR1;MAPK3;SOS2;HRAS |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 0.6185185 | 0.9358038 | 0.0645031 | -0.2936445 | -0.8796051 | 28 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY | 0.6264151 | 0.9358038 | 0.0647943 | -0.3961899 | -0.8808206 | 9 | MYL5;MYL7;MYL10 |
| KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM | 0.6214689 | 0.9358038 | 0.0650878 | -0.3830622 | -0.8815185 | 10 | EPHX2;EPHX4 |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.5969868 | 0.9298567 | 0.0670513 | -0.3876251 | -0.8920188 | 10 | MYL5;MYL7;MYL10;ROCK1 |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S | 0.6188679 | 0.9358038 | 0.0653834 | -0.4017303 | -0.8931382 | 9 | CCND1 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RAS_UBIQUITINATION_BY_CUL3_COMPLEX | 0.6302368 | 0.9358038 | 0.0628004 | -0.4561250 | -0.8938582 | 6 | CUL3;HRAS;RIT1;KRAS |
| KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY | 0.5939850 | 0.9285640 | 0.0672065 | -0.4157827 | -0.8940076 | 8 | ACVR2B;SMAD5;MSTN;SMAD1;ACVR1B;SMAD4 |
| KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5940410 | 0.9285640 | 0.0667426 | -0.3774908 | -0.8975368 | 11 | RET;MAPK3 |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 0.6286232 | 0.9358038 | 0.0626618 | -0.3201420 | -0.8993117 | 23 | ESR1 |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 0.5772059 | 0.9274249 | 0.0675189 | -0.3517439 | -0.9033980 | 15 | CCND1 |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.6213768 | 0.9358038 | 0.0632191 | -0.3217240 | -0.9037556 | 23 | ADCY1;ADCY9;ADCY6;ADCY5;CREB1 |
| KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM | 0.6204380 | 0.9358038 | 0.0636424 | -0.4874397 | -0.9037923 | 5 | GRIN2C;GRIN2B;GRIN2A |
| KEGG_MEDICUS_REFERENCE_ATR_SIGNALING | 0.5858209 | 0.9274249 | 0.0675189 | -0.3724616 | -0.9038505 | 12 | RPA4;ATRIP;RAD17 |
| KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA | 0.5827068 | 0.9274249 | 0.0681513 | -0.4213806 | -0.9060441 | 8 | TGFB3;FBN1;LTBP3 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S | 0.5808271 | 0.9274249 | 0.0683111 | -0.4229449 | -0.9094077 | 8 | CCND1 |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 0.5789474 | 0.9274249 | 0.0684715 | -0.3722124 | -0.9121453 | 13 | PDGFA;PDGFRB |
| KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY | 0.5772812 | 0.9274249 | 0.0681513 | -0.3839827 | -0.9129722 | 11 | TBK1;IFNA6;IFNA8;IFNA2;IFNA16;IFNA21;IFNA5;IFNA4;IFNA10 |
| KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.5899814 | 0.9285640 | 0.0668966 | -0.4420968 | -0.9142216 | 7 | BCL2 |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 0.5551537 | 0.9091009 | 0.0686326 | -0.3519854 | -0.9168584 | 16 | FZD8;FZD6;FZD3;FZD4;FZD10;ROR2;WNT5A;DVL1 |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.5938069 | 0.9285640 | 0.0656814 | -0.4686811 | -0.9184641 | 6 | CACNA1D |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382 | 0.5451128 | 0.8997995 | 0.0714786 | -0.3812367 | -0.9342604 | 13 | HEY1;NOTCH4;NOTCH3;MAML3;HES1;RBPJL |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S | 0.5344507 | 0.8941215 | 0.0720033 | -0.3984131 | -0.9472825 | 11 | CCND1 |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPG_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.5324675 | 0.8932179 | 0.0720033 | -0.4606510 | -0.9525903 | 7 | SKP1;BTRC |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P15_CELL_CYCLE_G1_S | 0.5150376 | 0.8860019 | 0.0743625 | -0.3923509 | -0.9614967 | 13 | CCND1 |
| KEGG_MEDICUS_REFERENCE_BILE_ACID_BIOSYNTHESIS | 0.4854015 | 0.8759869 | 0.0758887 | -0.3791951 | -0.9638785 | 14 | ACOX2;HSD17B4;SLC27A5;SCP2;AKR1D1;AKR1C4;HSD3B7;CYP7A1;CYP8B1 |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 0.5199275 | 0.8865982 | 0.0720033 | -0.3445913 | -0.9679922 | 23 | CACNA1H;CACNA1D |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.5116697 | 0.8860019 | 0.0723571 | -0.3579061 | -0.9724749 | 20 | PDE8B;PBX1;PDE11A;CREB1 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCND1_TO_CELL_CYCLE_G1_S | 0.5191257 | 0.8865982 | 0.0723571 | -0.4980626 | -0.9760424 | 6 | CCND1 |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 0.5000000 | 0.8792614 | 0.0751182 | -0.3261213 | -0.9768887 | 28 | UVSSA;POLR2L;MNAT1;CCNH;GTF2H5;CDK7 |
| KEGG_MEDICUS_VARIANT_AREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.4971751 | 0.8792614 | 0.0762797 | -0.4246692 | -0.9772663 | 10 | AREG |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.4953445 | 0.8792614 | 0.0758887 | -0.4124025 | -0.9805443 | 11 | AREG |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM | 0.5027322 | 0.8814538 | 0.0739901 | -0.5015161 | -0.9828103 | 6 | GRIN2C;GRIN2B;GRIN2A;PDYN |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 0.4693878 | 0.8683088 | 0.0785029 | -0.3156230 | -0.9933825 | 35 | ADCY1;SMARCD3;ADCY9 |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4672727 | 0.8683088 | 0.0776799 | -0.3215570 | -0.9948235 | 31 | ADCY1;ADCY9;PBX1;ADCY6;MRAP;ADCY5;CREB1 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.4673913 | 0.8683088 | 0.0774768 | -0.3448654 | -0.9999385 | 25 | CACNA1H;CAMK2B;CACNA1D |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 0.4638219 | 0.8673890 | 0.0791317 | -0.3178830 | -1.0004956 | 35 | FGFR3;FGFR2;FGFR1;FGF18;MAPK3;FGF10;SOS2;FGF20;FGF7;HRAS |
| KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.4397810 | 0.8527897 | 0.0810802 | -0.3950584 | -1.0042014 | 14 | IGF1R |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.4905660 | 0.8784637 | 0.0770737 | -0.4518112 | -1.0044794 | 9 | UQCRQ;UQCRB;CYC1;UQCRC2;UQCR11 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.4772313 | 0.8714047 | 0.0766747 | -0.5126761 | -1.0046801 | 6 | HTT;MAP3K10;MAP2K7;MAPK9 |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 0.4474638 | 0.8601866 | 0.0797706 | -0.3414296 | -1.0061217 | 26 | PHC3;BMI1;MBD5;MBD6;SCML1;CBX8;CBX4;PHC1 |
| KEGG_MEDICUS_REFERENCE_INTRINSIC_APOPTOTIC_PATHWAY | 0.4567669 | 0.8625115 | 0.0806388 | -0.4109231 | -1.0070099 | 13 | BCL2;PMAIP1 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.4548803 | 0.8625115 | 0.0797706 | -0.3131751 | -1.0071192 | 39 | NDUFA7;NDUFC2;NDUFB10;NDUFA2;NDUFS4;NDUFA5;NDUFA4;NDUFC1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION | 0.4754098 | 0.8706470 | 0.0768737 | -0.5140936 | -1.0074582 | 6 | ITPR1;GRM1 |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4371585 | 0.8527897 | 0.0813027 | -0.3251425 | -1.0101821 | 32 | ADCY1;ADCY9;PBX1;ADCY6;MRAP;ADCY5;CREB1 |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 0.4414414 | 0.8527897 | 0.0802023 | -0.2939749 | -1.0105159 | 50 | GRPR;AGTR1;PTGER3;OXTR;ADRA1B;ITPR2;EDNRA;HTR2B;ITPR1;EDNRB;F2R |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION | 0.4699248 | 0.8683088 | 0.0791317 | -0.4737364 | -1.0186186 | 8 | AGL;PYGL |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 0.4716981 | 0.8689915 | 0.0791317 | -0.4595226 | -1.0216236 | 9 | CREBBP;TBK1 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4398564 | 0.8527897 | 0.0802023 | -0.3370041 | -1.0228594 | 29 | ADCY1;ADCY9;PBX1;ADCY6;ADCY5;CREB1 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.4218182 | 0.8450015 | 0.0831291 | -0.3604529 | -1.0268503 | 24 | CACNA1H;CAMK2B;CACNA1D |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.4329710 | 0.8527897 | 0.0815265 | -0.3550590 | -1.0294949 | 25 | CACNA1H;CAMK2B;CACNA1D |
| KEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION | 0.4492481 | 0.8609430 | 0.0815265 | -0.4792894 | -1.0305586 | 8 | IDUA;IDS;HYAL1;HYAL3 |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 0.4422383 | 0.8527897 | 0.0802023 | -0.3919980 | -1.0307924 | 17 | MNAT1;CCNH;GTF2H5;CDK7;CETN2 |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_FKTN_TO_LARGE | 0.4576271 | 0.8625115 | 0.0806388 | -0.6889672 | -1.0337031 | 2 | FKTN |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.3996317 | 0.8268367 | 0.0867950 | -0.3224444 | -1.0369277 | 39 | NDUFA7;NDUFC2;NDUFB10;NDUFA2;NDUFS4;NDUFA5;NDUFA4;NDUFC1 |
| KEGG_MEDICUS_REFERENCE_DOUBLE_HOLLIDAY_JUNCTION_RESOLUTION | 0.4397810 | 0.8527897 | 0.0810802 | -0.5620038 | -1.0420462 | 5 | SLX4 |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 0.3963636 | 0.8260912 | 0.0865400 | -0.3374160 | -1.0438876 | 31 | FGFR3;FGFR2;FGFR1;FGF18;FGF10;FGF20;FGF7;FGF3;AKT2;FGF19;FGF5;FGF17;FGF16;AKT3;FGF23;FGF8;FGF22 |
| KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 0.4298725 | 0.8527897 | 0.0822055 | -0.5333434 | -1.0451814 | 6 | MAGI2;MAGI1;PTEN;AKT2 |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 0.3609576 | 0.8063275 | 0.0925529 | -0.3212417 | -1.0470553 | 42 | DNALI1;TUBA3D;DNAH7;DNAH5;DCTN4 |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.3802559 | 0.8112004 | 0.0891647 | -0.3284219 | -1.0531108 | 38 | NDUFA7;NDUFC2;NDUFB10;NDUFA2;NDUFS4;NDUFA5;NDUFA4;NDUFC1 |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS | 0.4096834 | 0.8369440 | 0.0860347 | -0.4432444 | -1.0538752 | 11 | GLCE;EXTL2;EXTL1;NDST1;NDST4 |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 0.3992806 | 0.8268367 | 0.0855357 | -0.3936305 | -1.0558391 | 19 | BMPR1B;ACVR2B;BMP4;BMPR2;GDF6 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 0.3554328 | 0.8063275 | 0.0934449 | -0.3204419 | -1.0580343 | 44 | DNALI1;TUBA3D;DNAH7;DNAH5;DCTN4;HTT |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3877917 | 0.8167596 | 0.0870516 | -0.3487725 | -1.0585781 | 29 | GLI3;WNT3;GLI1;WNT4;WNT2B;BMP4 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3877917 | 0.8167596 | 0.0870516 | -0.3487725 | -1.0585781 | 29 | GLI3;WNT3;GLI1;WNT4;WNT2B;BMP4 |
| KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME | 0.4174397 | 0.8389454 | 0.0847985 | -0.5140251 | -1.0629638 | 7 | PRKAR1A;PRKAR2A;PRKACG;PRKAR2B;PRKACB;PRKACA;PRKAR1B |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 0.3750000 | 0.8093931 | 0.0902635 | -0.4146731 | -1.0650216 | 15 | CCND1 |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 0.3522936 | 0.8063275 | 0.0937465 | -0.3047183 | -1.0655539 | 56 | NDUFAF1;NDUFC2;NDUFB10;NDUFA2;COA3;COX20;NDUFAF3;UQCRQ;NDUFS4;UQCRB;NDUFA4;CYC1;COX14;UQCRC2;NDUFAF6;NDUFAF2;NDUFA10;NDUFS8;COX11;COX16;COA5 |
| KEGG_MEDICUS_REFERENCE_COHESIN_LOADING | 0.4113208 | 0.8375248 | 0.0865400 | -0.4823930 | -1.0724699 | 9 | ATRX;MAU2;RAD21;NIPBL;STAG2 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 0.3621324 | 0.8063275 | 0.0922597 | -0.4199909 | -1.0786796 | 15 | TELO2;MLST8;ATG14;BECN1;DEPTOR |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.4007286 | 0.8268367 | 0.0860347 | -0.5534625 | -1.0846085 | 6 | ATG14;BECN1;ATXN3;PIK3C3;AMBRA1 |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 0.3593466 | 0.8063275 | 0.0919686 | -0.4089615 | -1.0864212 | 18 | FZD8;ZNRF3;RNF43;FZD6;LGR4;FZD3;RSPO1;FZD4;LGR5;FZD10;RSPO2 |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380 | 0.3582090 | 0.8063275 | 0.0937465 | -0.4519169 | -1.0966642 | 12 | HEY1;JAG1;NOTCH4;NOTCH3;MAML3;HES1;RBPJL |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.3580470 | 0.8063275 | 0.0919686 | -0.4211573 | -1.0970387 | 16 | CCND1;MAPK3;SOS2;EGF;HRAS |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.3400735 | 0.8063275 | 0.0959207 | -0.4296400 | -1.1034618 | 15 | CCND1 |
| KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY | 0.3684211 | 0.8063275 | 0.0925529 | -0.5135519 | -1.1042289 | 8 | SMAD3;TGFB3 |
| KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY | 0.3665414 | 0.8063275 | 0.0928481 | -0.5143331 | -1.1059087 | 8 | SMAD3;ACVR2B;NODAL;ACVR1C;ACVR1B;SMAD4 |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 0.3308271 | 0.8063275 | 0.0988903 | -0.4517810 | -1.1071366 | 13 | IGF1R;TSC2 |
| KEGG_MEDICUS_REFERENCE_TSC1_2_MTORC1_SIGNALING_PATHWAY | 0.3351955 | 0.8063275 | 0.0975449 | -0.4697730 | -1.1169507 | 11 | TELO2;MLST8;TSC2;DEPTOR;TSC1;AKT1S1 |
| KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY | 0.3352166 | 0.8063275 | 0.0982123 | -0.4859482 | -1.1182840 | 10 | ADCY9;ADCY6 |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 0.3138686 | 0.8063275 | 0.1002791 | -0.4414745 | -1.1221867 | 14 | RPA4;BRCA1 |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY | 0.3314501 | 0.8063275 | 0.0988903 | -0.4880416 | -1.1231014 | 10 | CCND1;LEF1 |
| KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY | 0.3421053 | 0.8063275 | 0.0968878 | -0.5256882 | -1.1303244 | 8 | SMAD3;ACVR2B |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4 | 0.3065693 | 0.8063107 | 0.1017139 | -0.4458391 | -1.1332811 | 14 | FZD8;LRP6;FZD6;LRP4;FZD3;FZD4 |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 0.3221601 | 0.8063275 | 0.0999277 | -0.4774798 | -1.1352746 | 11 | KITLG |
| KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.3395176 | 0.8063275 | 0.0965630 | -0.5498811 | -1.1371111 | 7 | BCL2 |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.2707182 | 0.7686908 | 0.1101223 | -0.3581126 | -1.1372954 | 37 | CCND1;WNT3;WNT4;LRP6;WNT2B;AXIN2;LEF1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.2651934 | 0.7599754 | 0.1114627 | -0.3543643 | -1.1395767 | 39 | NDUFA7;NDUFC2;NDUFB10;NDUFA2;SNCA;NDUFS4;NDUFA5;NDUFA4;NDUFC1 |
| KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION | 0.3284672 | 0.8063275 | 0.0975449 | -0.6171384 | -1.1442746 | 5 | HGD;FAH;HPD |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 0.3074141 | 0.8063107 | 0.1009906 | -0.4395391 | -1.1449201 | 16 | HEY2;HEY1;HEYL;JAG1;NOTCH4;DLL1;JAG2;HES5 |
| KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY | 0.3188679 | 0.8063275 | 0.1013507 | -0.5176505 | -1.1508553 | 9 | BMPR1B |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY | 0.2835821 | 0.7861882 | 0.1079724 | -0.4748462 | -1.1523066 | 12 | CCND1;AXIN2;LEF1 |
| KEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE | 0.3010949 | 0.8063107 | 0.1028218 | -0.6271691 | -1.1628732 | 5 | XYLT1;XYLT2;B3GALT6 |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 0.2839060 | 0.7861882 | 0.1059203 | -0.4486083 | -1.1685436 | 16 | IGF1R;IGF2 |
| KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.3007519 | 0.8063107 | 0.1047328 | -0.5438122 | -1.1692941 | 8 | CCND1;LEF1 |
| KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY | 0.3061224 | 0.8063107 | 0.1028218 | -0.5664896 | -1.1714563 | 7 | CCND1;LEF1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.3060109 | 0.8063107 | 0.1017139 | -0.5985589 | -1.1729830 | 6 | HTT;ATG14;BECN1 |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 0.2943396 | 0.8026265 | 0.1063233 | -0.5298400 | -1.1779554 | 9 | FGFR2;FGFR1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.2806026 | 0.7861882 | 0.1092500 | -0.5123526 | -1.1790469 | 10 | HTT;UQCRQ;UQCRB;CYC1;UQCRC2;UQCR11 |
| KEGG_MEDICUS_REFERENCE_VALINE_DEGRADATION | 0.2932331 | 0.8026265 | 0.1063233 | -0.5487863 | -1.1799894 | 8 | ACADS;ALDH6A1;HIBADH;ECHS1;HIBCH |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.2567812 | 0.7514220 | 0.1123785 | -0.4556117 | -1.1867862 | 16 | ADCY1;ADCY9;ADCY6;ADCY5;GNAO1;GNAI1 |
| KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY | 0.2536496 | 0.7512398 | 0.1137873 | -0.4700372 | -1.1947905 | 14 | TELO2;MLST8;NPRL2;RRAGB;DEPTOR;NPRL3;AKT1S1 |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2495479 | 0.7426450 | 0.1142665 | -0.4593417 | -1.1965023 | 16 | ESR1;MAPK3;CHRNA9 |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 0.2720588 | 0.7689699 | 0.1096841 | -0.4658986 | -1.1965863 | 15 | ADCY1;ADCY9;ADCY6;ADCY5 |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2573529 | 0.7514220 | 0.1133129 | -0.4678508 | -1.2016001 | 15 | IGF1R;IGF2 |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_RXRA_LXRA_MEDIATED_TRANSCRIPTION | 0.2677596 | 0.7637934 | 0.1101223 | -0.6133262 | -1.2019221 | 6 | CCND1 |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2481343 | 0.7426450 | 0.1167392 | -0.4962939 | -1.2043536 | 12 | CCND1 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN | 0.2604736 | 0.7534259 | 0.1119183 | -0.6171860 | -1.2094860 | 6 | ATG14;UVRAG;BECN1 |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.2310469 | 0.7223134 | 0.1193484 | -0.4602001 | -1.2101357 | 17 | ADCY1;ADCY9;CX3CR1;ADCY6;ADCY5 |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_CAMP_SIGNALING_PATHWAY | 0.2445255 | 0.7426450 | 0.1162341 | -0.4775141 | -1.2137961 | 14 | ADCY1;ADCY9;ADCY6;ADCY5 |
| KEGG_MEDICUS_ENV_FACTOR_BPA_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2556391 | 0.7514220 | 0.1152400 | -0.4956738 | -1.2147005 | 13 | ESR1 |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 0.1803571 | 0.6453241 | 0.1364904 | -0.3624246 | -1.2152448 | 46 | CCND1;WNT3;WNT4;FZD8;LRP6;WNT2B;AXIN2;FZD6;LEF1 |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.1771020 | 0.6404710 | 0.1380222 | -0.3652881 | -1.2158946 | 45 | CCND1;WNT3;WNT4;FZD8;LRP6;WNT2B;AXIN2;FZD6;LEF1 |
| KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY | 0.2462406 | 0.7426450 | 0.1177658 | -0.4981281 | -1.2207149 | 13 | HEY1;JAG1;NOTCH4;DLL1;JAG2;NOTCH3;DLL4 |
| KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION | 0.2448980 | 0.7426450 | 0.1172497 | -0.5916027 | -1.2233882 | 7 | C5;C6;C8B;C7 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY | 0.2485876 | 0.7426450 | 0.1172497 | -0.5324948 | -1.2253990 | 10 | CCND1 |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 0.2368421 | 0.7330263 | 0.1204334 | -0.5016736 | -1.2294035 | 13 | GLI3;GLI1 |
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2093863 | 0.6932600 | 0.1262540 | -0.4693967 | -1.2343188 | 17 | COX6C;COX7A1;COX7C;COX4I2 |
| KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION | 0.2124060 | 0.6938389 | 0.1281429 | -0.5804933 | -1.2481652 | 8 | RABEP1;EEA1;RABGEF1;RAB5B;PIK3C3 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION | 0.2094340 | 0.6932600 | 0.1294429 | -0.5627652 | -1.2511555 | 9 | CLU;C6;C8B;C7;VTN;CD59 |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 0.2067669 | 0.6918309 | 0.1301056 | -0.5824509 | -1.2523742 | 8 | RET |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION | 0.2152134 | 0.6938389 | 0.1262540 | -0.6060483 | -1.2532607 | 7 | IDUA;HGSNAT;IDS;GNS |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.1583794 | 0.5991851 | 0.1492075 | -0.3802009 | -1.2553466 | 44 | MAPT;NDUFA7;NDUFC2;NDUFB10;NDUFA2;NDUFS4;NDUFA5;NDUFA4 |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 0.1966912 | 0.6726621 | 0.1321473 | -0.4918261 | -1.2631769 | 15 | ADCY1;ADCY9;ADCY6;ADCY5;PLN |
| KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY | 0.2059369 | 0.6918309 | 0.1294429 | -0.6120394 | -1.2656498 | 7 | BMPR1B;BMPR2 |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR | 0.1985428 | 0.6752637 | 0.1307771 | -0.6468203 | -1.2675596 | 6 | ACVR2B;BMPR2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS | 0.1902072 | 0.6651877 | 0.1364904 | -0.5570170 | -1.2818304 | 10 | SHC2;GAB2;SHC3;SOS2 |
| KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1940299 | 0.6680402 | 0.1342735 | -0.5286441 | -1.2828578 | 12 | KIF5C |
| KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.1917293 | 0.6667441 | 0.1357409 | -0.5244685 | -1.2852650 | 13 | HPGD;FUT8;EYA1;SIX4;HOXA11;MEIS1;GRIA3 |
| KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 0.1843575 | 0.6558467 | 0.1380222 | -0.5439302 | -1.2932696 | 11 | ERBB4 |
| KEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION | 0.1725417 | 0.6282549 | 0.1429011 | -0.6330689 | -1.3091371 | 7 | IVD;HMGCL;MCCC2;AUH;HMGCLL1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1573237 | 0.5991851 | 0.1482615 | -0.5033170 | -1.3110498 | 16 | COX6C;COX7A1;COX7C;COX4I2 |
| KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION | 0.1654135 | 0.6058638 | 0.1473312 | -0.6132292 | -1.3185531 | 8 | JAG1;MIB1;DLL1;JAG2;DLL4;NEURL1B;MIB2 |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR | 0.1587591 | 0.5991851 | 0.1482615 | -0.5234791 | -1.3306348 | 14 | VPS18;VPS41;VPS39;EPG5;TECPR2;MAP1LC3A |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 0.1616541 | 0.5991851 | 0.1492075 | -0.6216189 | -1.3365926 | 8 | LRP2;CDON |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 0.1399254 | 0.5605932 | 0.1608014 | -0.5606855 | -1.3606126 | 12 | ESR1 |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 0.1138790 | 0.4865365 | 0.1752040 | -0.4930389 | -1.3655190 | 21 | CACNA2D2;CACNG1;CACNG4;CACNG6;CACNB2 |
| KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY | 0.1129326 | 0.4865365 | 0.1782199 | -0.7001492 | -1.3720673 | 6 | PLCD4;ITPR2;ITPR1;PLCD3 |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION | 0.1340782 | 0.5460159 | 0.1644058 | -0.5797855 | -1.3785207 | 11 | ACADSB;ACADS |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.1094620 | 0.4802459 | 0.1830239 | -0.6676370 | -1.3806212 | 7 | ESR1 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1037736 | 0.4654772 | 0.1900233 | -0.6270161 | -1.3940001 | 9 | KIF5C |
| KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 0.1033835 | 0.4654772 | 0.1900233 | -0.6519310 | -1.4017691 | 8 | PGR |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1139706 | 0.4865365 | 0.1782199 | -0.5473925 | -1.4058902 | 15 | COX6C;COX7A1;COX7C;COX4I2 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0935780 | 0.4461554 | 0.1978220 | -0.4741958 | -1.4078001 | 27 | DNALI1;DNAH7;DNAH5;DCTN4;DNAI1;DNAL1;DNAH9;ACTR10;DNAH12;DNAH6;DNAI2;DCTN6 |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.0939850 | 0.4461554 | 0.1999152 | -0.6580868 | -1.4150050 | 8 | VPS18;VPS41;VPS39 |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 0.1066176 | 0.4747937 | 0.1847065 | -0.5551042 | -1.4256966 | 15 | RPA4;RBBP8;BRCA1;RAD50 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_PAI | 0.0692168 | 0.3693549 | 0.2311267 | -0.7276417 | -1.4259436 | 6 | SERPINA5;PLAT |
| KEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.0849057 | 0.4171159 | 0.2114002 | -0.6469012 | -1.4382092 | 9 | VPS18;VPS41;VPS39 |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 0.0729537 | 0.3732096 | 0.2220560 | -0.5207054 | -1.4421440 | 21 | CACNA2D2;CACNG1;CACNG4;CACNG6;CACNB2;RYR2;CACNA2D4;TRDN;CASQ2;CACNG2;CACNA2D3;CACNB4;CACNA2D1;CACNA1C;CACNG7 |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 0.0251175 | 0.1602861 | 0.3524879 | -0.4180733 | -1.4511217 | 54 | ERBB4;RET;FGFR3;MST1;PDGFD;ERBB3;FGFR2;FGFR1;NTRK2;PDGFA;PDGFRB;FGF18;ITPR2;FGF10;ITPR1;NTRK3;PDGFC;HGF;FGF20 |
| KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 0.0474453 | 0.2770624 | 0.2820134 | -0.7894945 | -1.4638508 | 5 | CYP21A2;HSD11B2 |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 0.0741410 | 0.3761747 | 0.2220560 | -0.5629519 | -1.4663881 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 |
| KEGG_MEDICUS_REFERENCE_RENIN_ANGIOTENSIN_SIGNALING_PATHWAY | 0.0244340 | 0.1575486 | 0.3524879 | -0.8009199 | -1.4850353 | 5 | AGTR1;AGT |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 0.0524412 | 0.3033750 | 0.2663507 | -0.5804128 | -1.5118706 | 16 | CCND1;PGR |
| KEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION | 0.0602637 | 0.3391437 | 0.2529611 | -0.6656469 | -1.5318140 | 10 | ACADSB;ACADS |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 0.0090044 | 0.0797310 | 0.3807304 | -0.4045220 | -1.5331974 | 91 | ERBB4;IGF1R;RET;KITLG;IGF2;AREG;FGFR3;PDGFD;ERBB3;FGFR2;INSR;FGFR1;NTRK2;PDGFA;PDGFRB;FGF18;NTF4;ARTN;MAPK3;FGF10;TEK;BDNF;NGFR;PDGFC;SOS2;HGF;FGF20;NTF3 |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 0.0069072 | 0.0705538 | 0.4070179 | -0.4068466 | -1.5340028 | 88 | ERBB4;IGF1R;KITLG;IGF2;AREG;FGFR3;PDGFD;ERBB3;FGFR2;INSR;FGFR1;NTRK2;PDGFA;PDGFRB;FGF18;NTF4;PIK3R1;FGF10;TEK;BDNF;NGFR;PDGFC;PIK3R2;SOS2;HGF;FGF20;NTF3;EGF;FLT3;FGF7;HRAS |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 0.0269185 | 0.1683083 | 0.3524879 | -0.5999696 | -1.5628124 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 0.0065848 | 0.0702753 | 0.4070179 | -0.4219339 | -1.5699625 | 82 | ERBB4;IGF1R;KITLG;IGF2;AREG;FGFR3;PDGFD;ERBB3;FGFR2;INSR;FGFR1;NTRK2;PDGFA;PDGFRB;FGF18;NTF4;PIK3R1;FGF10;TEK;BDNF;NGFR;PDGFC;PIK3R2;HGF;FGF20;NTF3;EGF;FLT3 |
| KEGG_MEDICUS_REFERENCE_CREATINE_PATHWAY | 0.0090164 | 0.0797310 | 0.3807304 | -0.8084445 | -1.5842912 | 6 | GAMT;CKMT2;GATM |
| KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS | 0.0070668 | 0.0705538 | 0.4070179 | -0.8935532 | -1.5860216 | 4 | SULT1A2;SULT1A1;SULT1A4 |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0131799 | 0.1022054 | 0.3807304 | -0.5427943 | -1.6114566 | 27 | DNALI1;DNAH7;DNAH5;DCTN4;DNAI1;DNAL1;SOD1;DNAH9;ACTR10;DNAH12;DNAH6;DNAI2;DCTN6 |
| KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 0.0143480 | 0.1083096 | 0.3807304 | -0.6885143 | -1.6370384 | 11 | IGF1R;IGF2 |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 0.0096417 | 0.0837377 | 0.3807304 | -0.5674861 | -1.6454284 | 25 | ERBB4;IGF1R;FGFR3;ERBB3;FGFR2;INSR;FGFR1;NTRK2;PDGFRB |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 0.0148248 | 0.1092450 | 0.3807304 | -0.5815040 | -1.6565758 | 24 | PIGT;PIGX;PIGB;PIGH;PIGV;PIGQ;PIGF;PIGG;PGAP1;PIGN;GPAA1;PIGP |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 0.0008783 | 0.0156389 | 0.4772708 | -0.9094042 | -1.6861829 | 5 | SCUBE2;HHAT;DISP1 |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 0.0045959 | 0.0526822 | 0.4070179 | -0.5948877 | -1.7248794 | 25 | CACNA2D2;CACNA1H;CACNG1;CACNA1D;CACNG4;CACNG6;CACNB2 |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0000100 | 0.0005151 | 0.5933255 | -0.8665585 | -2.0603633 | 11 | TFF1;ESR1;PGR;BCL2;KRT19 |
# Save fgseaRes_keg as txt file.
write.table(fgseaResTidy_kegg, file.path(output_dir, "pathway_analysis", "full_fgseaRes_kegRank.txt"), sep = "\t", row.names = FALSE, quote = FALSE)
# Mark "significant" if adjusted adj p-value <= 0.05, else "non-significant".
fgseaResTidy_kegg$adjPvalue <- ifelse(fgseaResTidy_kegg$padj <= 0.05, "significant", "non-significant")
# Create a ggplot of significant pathways, with bars colored based on adjusted p-value significance.
ggplot(fgseaResTidy_kegg[fgseaResTidy_kegg$padj < 0.05, ], aes(reorder(pathway, NES), NES, fill = adjPvalue)) +
geom_col() +
scale_fill_manual(values = cols) +
coord_flip() +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
labs(x = "Pathway", y = "Normalized Enrichment Score", title = "KEGG pathways NES Enrichment Score from GSEA")
# Plot significant pathways as points with a gradient color based on p-value and size based on a 'size' variable.
ggplot(fgseaResTidy_kegg[fgseaResTidy_kegg$padj < 0.05, ], aes(y=reorder(pathway, size),x= NES)) + geom_point(aes(color=padj,size=size)) +
scale_color_gradientn(colours = c("red","blue")) +
labs(x='Normalized Enrichment Score', y=NULL ) +
theme( axis.title = element_text(face='bold'), axis.text = element_text (face='bold'))
KEGG_LEGACY
# # Load KEGG_MEDICUS pathways. pathwaysKEGG_LEG <-
# gmtPathways(file.path(input_dir,"c2.cp.kegg_legacy.v2023.2.Hs.symbols.gmt"))
#
# # Perform fgsea with KEGG pathways fgseaResTidy_kegg_leg <-
# fgsea(pathwaysKEGG_LEG, ranks)
#
# # Organize and sort KEGG results by NES fgseaResTidy_kegg_leg <-
# fgseaResTidy_kegg_leg %>% as_tibble() %>% arrange(desc(NES))
#
# # Combine genes in leadingEdge with semicolons
# fgseaResTidy_kegg_leg$leadingEdge <- sapply(fgseaResTidy_kegg_leg$leadingEdge,
# paste, collapse = ";")
#
# # Show in a Tidy table of keg. kable(fgseaResTidy_kegg_leg) %>%
# kable_styling(bootstrap_options = c("striped", "hover", "condensed"),
# full_width = FALSE) %>% scroll_box(height = "400px")
#
# # Save fgseaRes_keg as txt file. write.table(fgseaResTidy_kegg_leg,
# file.path(output_dir,"pathway_analysis","full_fgseaRes_KEGGRank_legacy.txt"),
# sep = "\t", row.names = FALSE, quote = FALSE)
#
# # Plot significant pathways as points with a gradient color based on p-value
# and size based on a 'size' variable.
# ggplot(fgseaResTidy_kegg_leg[fgseaResTidy_kegg_leg$padj < 0.05, ],
# aes(y=reorder(pathway, size),x= NES)) + geom_point(aes(color=padj,size=size))
# + scale_color_gradientn(colours = c("red","blue")) + labs(x='Normalized
# Enrichment Score', y=NULL ) + theme( axis.title = element_text(face='bold'),
# axis.text = element_text (face='bold') )Over-Representation Analysis analysis (ORA)
To identifies whether certain gene sets are over-represented in a target gene group.
# Set a vector of differentially expressed genes for ORA
deGenes <- rownames(top_full)[top_full$pval < 0.05] # ? genes
# Defining the gene universe as all genes considered in the analysis
geneUniverse <- rownames(expr_data)
## Performing ORA
# ORA for Hallmark pathways
oraHallmark <- fora(pathways = pathwaysH, genes = deGenes, universe = geneUniverse, minSize = 15, maxSize = 500)
oraHallmark$Pathway_Set <- "Hallmark"
oraHallmark$Significance <- ifelse(oraHallmark$pval < 0.05, "Significant", "Not Significant")
# ORA for KEGG_MEDICUS pathways
oraKeggMed <- fora(pathways = pathwaysKEGG_MED, genes = deGenes, universe = geneUniverse, minSize = 15, maxSize = 500)
oraKeggMed$Pathway_Set <- "KEGG_MEDICUS"
oraKeggMed$Significance <- ifelse(oraKeggMed$pval < 0.05, "Significant", "Not Significant")
# # ORA for KEGG_LEGACY pathways
# oraKeggLeg <- fora(pathways = pathwaysKEGG_LEG, genes = deGenes, universe = geneUniverse, minSize = 15, maxSize = 500)
# oraKeggLeg$Pathway_Set <- "KEGG_LEGACY"
# oraKeggLeg$Significance <- ifelse(oraKeggLeg$pval < 0.05, "Significant", "Not Significant")
# Display the top results for each pathway set
kable(oraHallmark, caption = "Hallmark Pathway Enrichment Results") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance |
|---|---|---|---|---|---|---|---|
| HALLMARK_ADIPOGENESIS | 1 | 1 | 0 | 192 | Hallmark | Not Significant | |
| HALLMARK_ALLOGRAFT_REJECTION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | |
| HALLMARK_ANDROGEN_RESPONSE | 1 | 1 | 0 | 96 | Hallmark | Not Significant | |
| HALLMARK_ANGIOGENESIS | 1 | 1 | 0 | 36 | Hallmark | Not Significant | |
| HALLMARK_APICAL_JUNCTION | 1 | 1 | 0 | 190 | Hallmark | Not Significant | |
| HALLMARK_APICAL_SURFACE | 1 | 1 | 0 | 43 | Hallmark | Not Significant | |
| HALLMARK_APOPTOSIS | 1 | 1 | 0 | 159 | Hallmark | Not Significant | |
| HALLMARK_BILE_ACID_METABOLISM | 1 | 1 | 0 | 112 | Hallmark | Not Significant | |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 1 | 1 | 0 | 72 | Hallmark | Not Significant | |
| HALLMARK_COAGULATION | 1 | 1 | 0 | 137 | Hallmark | Not Significant | |
| HALLMARK_COMPLEMENT | 1 | 1 | 0 | 198 | Hallmark | Not Significant | |
| HALLMARK_DNA_REPAIR | 1 | 1 | 0 | 145 | Hallmark | Not Significant | |
| HALLMARK_E2F_TARGETS | 1 | 1 | 0 | 195 | Hallmark | Not Significant | |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 1 | 1 | 0 | 190 | Hallmark | Not Significant | |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 1 | 1 | 0 | 192 | Hallmark | Not Significant | |
| HALLMARK_FATTY_ACID_METABOLISM | 1 | 1 | 0 | 152 | Hallmark | Not Significant | |
| HALLMARK_G2M_CHECKPOINT | 1 | 1 | 0 | 188 | Hallmark | Not Significant | |
| HALLMARK_GLYCOLYSIS | 1 | 1 | 0 | 197 | Hallmark | Not Significant | |
| HALLMARK_HEDGEHOG_SIGNALING | 1 | 1 | 0 | 35 | Hallmark | Not Significant | |
| HALLMARK_HEME_METABOLISM | 1 | 1 | 0 | 189 | Hallmark | Not Significant | |
| HALLMARK_HYPOXIA | 1 | 1 | 0 | 191 | Hallmark | Not Significant | |
| HALLMARK_IL2_STAT5_SIGNALING | 1 | 1 | 0 | 194 | Hallmark | Not Significant | |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 1 | 1 | 0 | 87 | Hallmark | Not Significant | |
| HALLMARK_INFLAMMATORY_RESPONSE | 1 | 1 | 0 | 197 | Hallmark | Not Significant | |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 1 | 1 | 0 | 94 | Hallmark | Not Significant | |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 1 | 1 | 0 | 194 | Hallmark | Not Significant | |
| HALLMARK_KRAS_SIGNALING_DN | 1 | 1 | 0 | 191 | Hallmark | Not Significant | |
| HALLMARK_KRAS_SIGNALING_UP | 1 | 1 | 0 | 191 | Hallmark | Not Significant | |
| HALLMARK_MITOTIC_SPINDLE | 1 | 1 | 0 | 197 | Hallmark | Not Significant | |
| HALLMARK_MTORC1_SIGNALING | 1 | 1 | 0 | 194 | Hallmark | Not Significant | |
| HALLMARK_MYC_TARGETS_V1 | 1 | 1 | 0 | 193 | Hallmark | Not Significant | |
| HALLMARK_MYC_TARGETS_V2 | 1 | 1 | 0 | 57 | Hallmark | Not Significant | |
| HALLMARK_MYOGENESIS | 1 | 1 | 0 | 196 | Hallmark | Not Significant | |
| HALLMARK_NOTCH_SIGNALING | 1 | 1 | 0 | 32 | Hallmark | Not Significant | |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 1 | 1 | 0 | 184 | Hallmark | Not Significant | |
| HALLMARK_P53_PATHWAY | 1 | 1 | 0 | 191 | Hallmark | Not Significant | |
| HALLMARK_PANCREAS_BETA_CELLS | 1 | 1 | 0 | 40 | Hallmark | Not Significant | |
| HALLMARK_PEROXISOME | 1 | 1 | 0 | 104 | Hallmark | Not Significant | |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 1 | 1 | 0 | 104 | Hallmark | Not Significant | |
| HALLMARK_PROTEIN_SECRETION | 1 | 1 | 0 | 94 | Hallmark | Not Significant | |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 1 | 1 | 0 | 47 | Hallmark | Not Significant | |
| HALLMARK_SPERMATOGENESIS | 1 | 1 | 0 | 132 | Hallmark | Not Significant | |
| HALLMARK_TGF_BETA_SIGNALING | 1 | 1 | 0 | 54 | Hallmark | Not Significant | |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 1 | 1 | 0 | 197 | Hallmark | Not Significant | |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 1 | 1 | 0 | 106 | Hallmark | Not Significant | |
| HALLMARK_UV_RESPONSE_DN | 1 | 1 | 0 | 138 | Hallmark | Not Significant | |
| HALLMARK_UV_RESPONSE_UP | 1 | 1 | 0 | 154 | Hallmark | Not Significant | |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 1 | 1 | 0 | 42 | Hallmark | Not Significant | |
| HALLMARK_XENOBIOTIC_METABOLISM | 1 | 1 | 0 | 194 | Hallmark | Not Significant |
kable(oraKeggMed, caption = "KEGG Medicus Pathway Enrichment Results") %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance |
|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 1 | 1 | 0 | 33 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 1 | 1 | 0 | 34 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 38 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 32 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 44 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 1 | 1 | 0 | 38 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 82 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 91 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 88 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 32 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 1 | 1 | 0 | 50 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 1 | 1 | 0 | 32 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 1 | 1 | 0 | 56 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 1 | 1 | 0 | 30 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 1 | 1 | 0 | 41 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 42 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 1 | 1 | 0 | 54 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 1 | 1 | 0 | 33 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 1 | 1 | 0 | 81 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 1 | 1 | 0 | 28 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 1 | 1 | 0 | 46 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 31 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 1 | 1 | 0 | 37 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 1 | 1 | 0 | 45 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 1 | 1 | 0 | 44 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 21 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 22 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 17 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 44 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 24 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 1 | 1 | 0 | 39 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 40 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 1 | 1 | 0 | 39 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 1 | 1 | 0 | 25 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 1 | 1 | 0 | 23 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 1 | 1 | 0 | 15 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 20 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 1 | 1 | 0 | 39 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 1 | 1 | 0 | 26 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 1 | 1 | 0 | 29 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 1 | 1 | 0 | 27 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 39 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 39 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 1 | 1 | 0 | 35 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1 | 1 | 0 | 19 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 1 | 1 | 0 | 16 | KEGG_MEDICUS | Not Significant | |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 1 | 1 | 0 | 18 | KEGG_MEDICUS | Not Significant |
# kable(oraKeggLeg, caption = "KEGG Legacy Pathway Enrichment Results") %>%
# kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
# scroll_box(height = "400px")
write.table(transform(oraHallmark, overlapGenes = sapply(overlapGenes, paste, collapse = ",")),
file = file.path(output_dir, "pathway_analysis", "Hallmark_ORA_Results.csv"),
sep = "\t", row.names = FALSE, quote = FALSE)
write.table(transform(oraKeggMed, overlapGenes = sapply(overlapGenes, paste, collapse = ",")),
file = file.path(output_dir, "pathway_analysis", "KeggMed_ORA_Results.csv"),
sep = "\t", row.names = FALSE, quote = FALSE)
# write.table(transform(oraKeggLeg, overlapGenes = sapply(overlapGenes, paste, collapse = ",")),
# file = file.path(output_dir, "pathway_analysis", "KeggLeg_ORA_Results.csv"),
# sep = "\t", row.names = FALSE, quote = FALSE)6. DE by Treatment (R vs NR)
Treatment groups: "chemo",
"chemo+targeted", "IO+chemo",
"targeted"
Summary of Differentially Expressed Genes by Treatment
| Treatment | FDR < 0.05 | FDR < 0.05 & High FC | **Significant Genes ( |
|---|---|---|---|
| Chemo | 0 | 0 | – |
| Chemo + Targeted | 4,152 | 1 | AGR3 |
| IO + Chemo | 521 | 47 | CA12, SLC7A2, LAMP3, CCDC74B, CCL13, ACOX2, AGR2, SCUBE2, GDF15, CRABP1, TNNT1, ELF5, ANXA9, AGR3, ROPN1, IDO1, FOXA1, PROM1, TFF1, TFF3, DYNLRB2, CHI3L1, DNALI1, FSIP1, DHRS2, CLSTN2, EEF1A2, CHI3L2, KRT23, GABRP, CXCL13, GSTA5, MSMB, ROPN1B, KRT5, MARCO, NAT1, CXCL9, STMND1, PPP1R14C, UBD, AR, VGLL1, KRT15, GATA3, PDZK1, MIA |
| Targeted | 5 | 3 | GRB7, MNX1, PNMT |
# Frequency table for the treatment columns
DT::datatable(as.data.frame(table(merged_clin$treatment)),
colnames = c("Treatment", "Count"))treatment_list <- c("chemo", "chemo+targeted", "IO+chemo", "targeted")
sig_gene_list <- list()
top_table_list <- list()
for (treatment in treatment_list) {
cat("\nProcessing:", treatment, "\n")
# Subset data
clin_sub <- clin_data[clin_data$treatment == treatment, ]
matched_ids <- clin_sub$patientid[clin_sub$patientid %in% colnames(expr_data)]
expr_sub <- expr_data[, matched_ids]
# Design and fit
design <- model.matrix(~ clin_sub$response)
fit <- lmFit(expr_sub, design)
fit <- eBayes(fit)
top.table <- topTable(fit, sort.by = "P", n = Inf)
# Count DE genes (adj.P.Val)
cat("DE genes (adj.P.Val < 0.05):", sum(top.table$adj.P.Val < 0.05), "\n")
# Prepare for plotting (remove non-numeric cols)
top.table.clean <- top.table[, sapply(top.table, is.numeric)]
rownames(top.table.clean) <- rownames(top.table)
# Volcano plot: P-value
print(EnhancedVolcano(top.table.clean,
lab = rownames(top.table.clean),
x = 'logFC',
y = 'P.Value',
pCutoff = 0.05,
FCcutoff = 1.5,
xlim = c(-5, 5),
ylim = c(0, 8),
title = paste("Volcano Plot (P value) -", treatment)
))
# Volcano plot: FDR
print(EnhancedVolcano(top.table.clean,
lab = rownames(top.table.clean),
x = 'logFC',
y = 'adj.P.Val',
pCutoff = 0.05,
FCcutoff = 1.5,
xlim = c(-5, 5),
ylim = c(0, 8),
legendLabels = c('Not sig.', 'Log FC', 'adj p-value', 'adj p-value & Log FC'),
title = paste("Volcano Plot (FDR) -", treatment)
))
# Save top table
top.table$Gene <- rownames(top.table)
file_name <- paste0(gsub("\\+", "_", treatment), "_limma_fit.txt")
write.table(top.table, file = file.path(output_dir,"DEG_analysis", file_name),
row.names = FALSE, sep = "\t", quote = FALSE)
# Show datatable
top.display <- top.table
top.display[, sapply(top.display, is.numeric)] <- round(top.display[, sapply(top.display, is.numeric)], 3)
print(DT::datatable(top.display, caption = paste("TopTable -", treatment)))
# Significant gene names
sig_genes <- rownames(top.table)[top.table$adj.P.Val < 0.05 & abs(top.table$logFC) >= 1.5]
cat("DE genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5):", length(sig_genes), "\n")
cat("Significant gene names:\n")
# Store in a named list
top_table_list[[treatment]] <- top.table
sig_gene_list[[treatment]] <- sig_genes
print(sig_genes)
# Optionally save gene list
gene_file <- paste0(gsub("\\+", "_", treatment), "_significant_genes.txt")
writeLines(sig_genes, file.path(output_dir,"DEG_analysis", gene_file))
}Processing: chemo DE genes (adj.P.Val < 0.05): 0
DE
genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5): 0 Significant gene
names: character(0)
Processing: chemo+targeted DE genes (adj.P.Val < 0.05): 4152
DE
genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5): 1 Significant gene
names: [1] “AGR3”
Processing: IO+chemo DE genes (adj.P.Val < 0.05): 521
DE
genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5): 47 Significant gene
names: [1] “CA12” “SLC7A2” “LAMP3” “CCDC74B” “CCL13” “ACOX2”
[7] “AGR2” “SCUBE2” “GDF15” “CRABP1” “TNNT1” “ELF5”
[13] “ANXA9” “AGR3” “ROPN1” “IDO1” “FOXA1” “PROM1”
[19] “TFF1” “TFF3” “DYNLRB2” “CHI3L1” “DNALI1” “FSIP1”
[25] “DHRS2” “CLSTN2” “EEF1A2” “CHI3L2” “KRT23” “GABRP”
[31] “CXCL13” “GSTA5” “MSMB” “ROPN1B” “KRT5” “MARCO”
[37] “NAT1” “CXCL9” “STMND1” “PPP1R14C” “UBD” “AR”
[43] “VGLL1” “KRT15” “GATA3” “PDZK1” “MIA”
Processing: targeted DE genes (adj.P.Val < 0.05): 5
DE
genes (adj.P.Val < 0.05 & abs(logFC) ≥ 1.5): 3 Significant gene
names: [1] “GRB7” “MNX1” “PNMT”
7. Enrichment by Treatment
MSigDB Hallmark Gene Sets
fgsea_result_list <- list()
fgsea_plot_list <- list()
for (treatment in names(top_table_list)) {
message("Running GSEA for: ", treatment)
# Get ranked genes
top_full <- top_table_list[[treatment]]
ranks <- top_full$logFC
names(ranks) <- top_full$Gene
ranks <- sort(ranks, decreasing = TRUE)
# Run GSEA
#fgseaRes <- fgsea(pathways = pathwaysH, stats = ranks)
fgseaRes <- fgsea(pathways = pathwaysH, stats = ranks, nproc = 1)
fgseaRes <- na.omit(fgseaRes)
fgseaResTidy <- fgseaRes %>%
as_tibble() %>%
arrange(desc(NES)) %>%
mutate(
leadingEdge = sapply(leadingEdge, paste, collapse = ";"),
adjPvalue = ifelse(padj <= 0.05, "significant", "non-significant")
)
fgsea_result_list[[treatment]] <- fgseaResTidy
# Barplot for NES
p <- ggplot(fgseaResTidy, aes(reorder(pathway, NES), NES, fill = adjPvalue)) +
geom_col() +
scale_fill_manual(values = c("significant" = "red", "non-significant" = "grey")) +
coord_flip() +
theme_minimal() +
labs(title = paste("Hallmark NES -", treatment), x = "Pathway", y = "Normalized Enrichment Score")
fgsea_plot_list[[treatment]] <- p
print(p)
print(
kable(fgseaResTidy, caption = paste("fgsea results -", treatment)) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")
)
}| | | 0% | |=== | 5% | |====== | 9% | |========== | 14% | |============= | 18% | |================ | 23% | |=================== | 27% | |====================== | 32% | |========================= | 36% | |============================= | 41% | |================================ | 45% | |=================================== | 50% | |====================================== | 55% | |========================================= | 59% | |============================================= | 64% | |================================================ | 68% | |=================================================== | 73% | |====================================================== | 77% | |========================================================= | 82% | |============================================================ | 86% | |================================================================ | 91% | |=================================================================== | 95% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 0.0000000 | 0.0000000 | 1.8202395 | 0.7054869 | 3.9309901 | 194 | IDO1;CXCL9;CXCL10;SOD2;SLAMF7;CCL5;CXCL11;CD38;GZMA;HLA-DRB1;PSMB9;HLA-DMA;GBP4;ICAM1;CCL2;HLA-DQA1;IL2RB;CFB;IFI30;CD74;XCL1;HLA-A;TAP1;FPR1;VCAM1;CASP1;CASP4;BATF2;STAT1;IL15;C1S;FGL2;VAMP5;PLA2G4A;CD40;SPPL2A;IRF1;LCP2;CCL7;PLSCR1;TNFSF10;CD69;HLA-B;NMI;RIPK2;PFKP;B2M;IRF8;PSMB8;IL10RA;GPR18;SERPING1;LAP3;BANK1;PNP;ITGB7;ISG20;SOCS1;CD274;IL18BP;FAS;BST2;IL7;MTHFD2;OGFR;UBE2L6;PSMB10;LYSMD2;JAK2;IFI35;C1R;PTPN6;UPP1;P2RY14;BPGM;NAMPT;PSMB2;PTPN2;IL15RA;CIITA;SOCS3;LY6E;IFNAR2;IRF4;PIM1;APOL6;PML;PSMA2;SAMD9L;CFH;PSME2;EPSTI1;LGALS3BP;MVP;PDE4B;OAS2;ZBP1;CMKLR1;GCH1;IFITM3;NUP93;PELI1;TRIM26;PSMA3 | significant |
| HALLMARK_ALLOGRAFT_REJECTION | 0.0000000 | 0.0000000 | 1.7147970 | 0.6781194 | 3.7844292 | 195 | CXCL13;CXCL9;GZMB;CCL4;CCL5;CD2;CD3D;GZMA;CDKN2A;HLA-DRA;HLA-DMA;ICAM1;LCK;IL27RA;CCL2;HLA-DQA1;IL2RB;TLR1;CD79A;LTB;CD74;HLA-A;CD247;TAP1;CD3G;HLA-E;CD8A;CXCR3;IL18;CAPG;SIT1;IL1B;IFNG;STAT1;EGFR;IL15;TLR2;CD40;LCP2;ZAP70;FLNA;GBP2;HCLS1;CCL7;CCR5;RIPK2;IFNGR1;CCL13;FASLG;TNF;LY75;NCK1;IL2RG;B2M;IRF8;LYN;CD96;CTSS;IGSF6;GPR65;SOCS1;CD8B;CCL19;NCF4;FAS;CD4;HLA-DOB;IL7;C2;SRGN;PSMB10;JAK2;ITGB2;FCGR2B;PTPN6;HLA-DMB;ITK;MMP9;CCR2;TLR6;MAP4K1;HLA-DOA;UBE2D1;TRAT1;CSK;LY86;TGFB1;CD47;IL18RAP;TIMP1;IFNGR2;IFNAR2;IRF4;KLRD1 | significant |
| HALLMARK_E2F_TARGETS | 0.0000000 | 0.0000000 | 1.3951871 | 0.5872240 | 3.2771628 | 195 | CDKN2A;CDK1;TFRC;RAD51C;TK1;MYBL2;DONSON;MCM5;CDC20;DEK;KIF2C;CCNE1;MCM6;SMC6;CCNB2;LBR;BIRC5;MCM2;PRDX4;TUBB;CKS1B;RRM2;CDCA3;CDCA8;DLGAP5;ATAD2;CKS2;AURKA;MAD2L1;CDKN2C;KPNA2;CDKN3;XRCC6;POLD3;POLA2;MELK;MTHFD2;CHEK1;SPC25;RNASEH2A;RAD1;E2F8;EED;USP1;NASP;DCK;MCM7;UBE2T;BARD1;HMGB2;SNRPB;SYNCRIP;CENPM;ANP32E;ORC6;PTTG1;RAN;CENPE;PRPS1;UBE2S;HMGA1;PAICS;SPC24;MMS22L;MSH2;TOP2A;RFC2;SLBP;RANBP1;WEE1;CSE1L;ASF1B;BUB1B;TIPIN;DSCC1;RAD51AP1;DDX39A;CDC25B;PLK1;SMC4;KIF4A;MCM3;DIAPH3;XPO1;SSRP1;SRSF2;EZH2;TRA2B;HMMR;RPA2;PRIM2;CDK4 | significant |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 0.0000000 | 0.0000000 | 1.1239150 | 0.6518779 | 3.2266117 | 94 | CXCL10;CXCL11;PSMB9;GBP4;LAMP3;IFI30;CD74;TAP1;CASP1;BATF2;IL15;C1S;IRF1;GBP2;HLA-C;PLSCR1;NCOA7;NMI;RIPK2;B2M;PSMB8;LAP3;ISG20;IFITM1;BST2;IL7;OGFR;UBE2L6;IFI35;CD47;MVB12A;LY6E;SAMD9L;PSME2;PROCR;EPSTI1;NUB1;LGALS3BP;CCRL2 | significant |
| HALLMARK_MTORC1_SIGNALING | 0.0000000 | 0.0000000 | 1.3267161 | 0.5751547 | 3.2047760 | 194 | FADS2;CORO1A;IFI30;TUBA4A;TFRC;FADS1;ACTR3;DDIT4;CCT6A;PHGDH;CTSC;GMPS;DAPP1;FGL2;PSAT1;PPA1;PSPH;MCM2;DHCR7;PSMA4;SLA;RRM2;ENO1;PGM1;IDI1;LDHA;AURKA;PNP;BUB1;EEF1E1;PFKL;CXCR4;DHCR24;ARPC5L;HMGCS1;MTHFD2;GLRX;EBP;ASNS;IFRD1;ITGB2;SRD5A1;PSMD13;PSMC4;HPRT1;SKAP2;PSMG1;STIP1;PSMC2;PRDX1;PSMD14;PLOD2;FKBP2;SQSTM1;NAMPT;RPN1;SERPINH1;IDH1;SDF2L1;GLA;ELOVL5;UCHL5;STARD4;LTA4H;EDEM1;MLLT11;VLDLR;PDK1;LDLR;ACTR2;SQLE;GAPDH;ME1;PNO1;LGMN;DDX39A;GOT1;PLK1;GSR;SCD;PSMD12;GTF2H1;TPI1;TES;PSMB5;SLC1A5;PSMA3;PPP1R15A;P4HA1;HSP90B1;HSPE1;CALR;GSK3B;CD9;SEC11A;HMGCR;PIK3R3;DHFR | significant |
| HALLMARK_INFLAMMATORY_RESPONSE | 0.0000000 | 0.0000000 | 1.2545135 | 0.5445961 | 3.0518244 | 197 | CXCL9;MARCO;CXCL10;CCL5;CXCL11;LAMP3;ICAM1;LCK;CCL2;IL2RB;TLR1;EDN1;FPR1;CD48;GPR183;IL18;CYBB;CXCR6;RGS1;EMP3;IL1B;IL15;CCR7;PTAFR;PLAUR;TLR2;CD40;IRF1;LCP2;RHOG;CCL7;TNFSF10;CD69;NMI;RIPK2;AQP9;LYN;ADRM1;IL10RA;OSM;CD14;PTGER4;IFITM1;BST2;SLAMF1;CD82;EBI3;AXL;CX3CL1;C3AR1;RNF144B;ADM;ADORA2B;TNFRSF9;NAMPT;IL15RA;MSR1;PDPN;OSMR;IL18RAP;CD70;SLC31A1;TIMP1;IFNGR2;LY6E | significant |
| HALLMARK_MYC_TARGETS_V1 | 0.0000000 | 0.0000000 | 1.2039752 | 0.5298891 | 2.9434352 | 193 | MCM5;CDC20;ODC1;DEK;RFC4;CDC45;MCM6;MCM2;PSMA4;PRDX4;TXNL4A;PSMA7;CLNS1A;LDHA;MAD2L1;CCNA2;KPNA2;XRCC6;PSMB3;CCT7;IFRD1;SNRPD1;POLE3;PSMC4;HPRT1;SNRPG;USP1;CCT4;EIF4A1;PSMD14;MCM7;HNRNPA2B1;SRM;CCT3;SNRPA1;TYMS;PSMB2;SYNCRIP;SRPK1;RAN;YWHAQ;CSTF2;EIF4G2;RANBP1;PSMA2;PPM1G;PSMA1;XPO1;RPS10;SNRPD3;HDGF;RRM1;LSM2;SNRPA;RPS3;SRSF2;TRA2B;C1QBP;CDK4;UBA2;PSMD7;CAD;DDX21;PSMA6;HSPE1;MRPL23;PCNA;RUVBL2;COX5A;NDUFAB1;PRPS2;PRPF31;FBL;UBE2L3;PRDX3;PSMD8;U2AF1;HDDC2;HSPD1;CBX3;LSM7;EIF2S1;EXOSC7;MCM4;TRIM28;NME1;SET;CTPS1;TCP1;AP3S1;PSMD1;EEF1B2;COPS5;XPOT;NOP16;VBP1;SLC25A3;ABCE1;TFDP1;NCBP1;ACP1 | significant |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.0000000 | 0.0000000 | 0.9436322 | 0.5971414 | 2.9338583 | 87 | CXCL13;CXCL9;CXCL10;CXCL11;CD38;LTB;IL1B;STAT1;CXCL1;TLR2;A2M;IRF1;CCL7;CD44;IFNGR1;TNF;IL2RG;SOCS1;CD14;GRB2;TNFRSF12A;FAS;IL7;TNFRSF21;EBI3;PTPN2;IL15RA;TGFB1;OSMR;SOCS3;HAX1;IFNGR2;PIM1;BAK1;IL10RB;JUN;IL13RA1;CSF2RA | significant |
| HALLMARK_COMPLEMENT | 0.0000000 | 0.0000000 | 1.1690700 | 0.5103279 | 2.8496281 | 198 | S100A9;GZMB;CCL5;GZMK;CP;GZMA;PSMB9;LCK;SERPINA1;C1QA;C1QC;CFB;C3;FCER1G;CTSV;CASP1;CASP4;CTSC;CXCL1;APOC1;PLAUR;PLEK;C1S;PLA2G7;CASP5;SPOCK2;PLA2G4A;IRF1;LCP2;RHOG;CTSL;PLSCR1;PFN1;CTSB;APOBEC3G;CEBPB;GNB4;LYN;CTSS;SERPING1;LAP3;CTSD;GRB2;LIPA;C2;APOBEC3F;KYNU;JAK2;C1R;PREP;GNAI2;ANXA5;EHD1;CTSH;CPQ;ACTN2;FCN1;MSRB1;GNGT2;KIF2A;LTA4H;TIMP1;PIM1;GNB2;PHEX;ME1;CFH;ITGAM;LGMN;TIMP2 | significant |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.0000000 | 0.0000000 | 1.0768682 | 0.4899619 | 2.7456634 | 197 | CXCL10;CCL4;SOD2;CCL5;CXCL11;ICAM1;CCL2;BIRC3;EDN1;TAP1;GPR183;IL18;IL1B;RCAN1;CD83;CXCL1;PLAU;SGK1;PLAUR;PLEK;TLR2;IRF1;SAT1;MARCKS;BCL2A1;CD69;RIPK2;CD44;TNF;CEBPB;GFPT2;GADD45A;TNFAIP8;FOS;DUSP1;PTGER4;PANX1;DRAM1;KYNU;ZFP36;NFKBIE;TRIP10;TRIB1;EHD1;DUSP4;BTG3;TNFRSF9;SQSTM1;TRAF1;NAMPT;IL15RA;SLC2A6;JUNB;SERPINB8;SOCS3;LAMB3;IFNGR2;LDLR;MCL1;JUN;ID2;DUSP2;ZC3H12A;TANK;CCRL2;OLR1;PNRC1;PDE4B;PDLIM5;GCH1;BIRC2;RELB;PPP1R15A;LITAF;CCNL1;IL7R;PHLDA2;EGR2;STAT5A;CFLAR;PTX3;CEBPD;TNFAIP2;TNFAIP3 | significant |
| HALLMARK_G2M_CHECKPOINT | 0.0000000 | 0.0000000 | 1.0073180 | 0.4768520 | 2.6307748 | 188 | CDK1;MYBL2;CENPA;MCM5;CDC20;ODC1;KIF2C;TTK;NDC80;CDC45;FBXO5;MCM6;MARCKS;CCNB2;LBR;BIRC5;MCM2;PBK;UBE2C;CKS1B;CKS2;AURKA;MAD2L1;CDKN2C;CCNA2;BUB1;KPNA2;CDKN3;TPX2;POLA2;CHEK1;UCK2;KIF15;SNRPD1;E2F1;CDC7;E2F3;AMD1;NASP;PRC1;KIF11;BARD1;KIF23;SYNCRIP;ORC6;TGFB1;PTTG1;SAP30;CENPE;UBE2S;HMGA1;KATNA1;TOP2A;ATF5;NUSAP1;PML;SQLE;INCENP;TROAP;DDX39A;CDC25B;PLK1;HSPA8;EXO1;SMC4;KIF4A;MCM3;XPO1;SRSF2;EZH2;TRA2B;HMMR;RPA2;PRIM2;CDK4;SMC2;DTYMK;CENPF;RAD54L;STMN1;CBX1;PLK4;RACGAP1;LMNB1;DR1;FANCC;NEK2;CHAF1A;NUP50;STAG1 | significant |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 0.0000003 | 0.0000008 | 0.6749629 | 0.5024611 | 2.3453773 | 72 | FADS2;FDPS;ACAT2;PLAUR;FDFT1;FBXO6;S100A11;PLSCR1;DHCR7;IDI1;MVD;PCYT2;TNFRSF12A;HMGCS1;CXCL16;EBP;FASN;ANXA5;NSDHL;SREBF2;STARD4;ATF5;LDLR;SQLE;ACTG1;LGMN;SCD;GUSB;PNRC1;ETHE1;PMVK;GPX8;STX5;MVK;CD9;HMGCR;LSS;CYP51A1;ECH1;CHKA;ERRFI1 | significant |
| HALLMARK_IL2_STAT5_SIGNALING | 0.0000000 | 0.0000000 | 0.8513391 | 0.4141865 | 2.3078571 | 194 | CXCL10;GBP4;ICOS;IL2RB;LTB;CD48;BATF3;CAPG;ODC1;CD83;FGL2;TGM2;CCNE1;CTSZ;PLSCR1;TNFSF10;TNFRSF8;CD44;IFNGR1;TNFRSF4;IRF8;CD79B;IL10RA;GSTO1;ANXA4;PNP;GPR65;HOPX;SOCS1;MUC1;GALM;TNFRSF18;CD81;TNFRSF21;SPP1;UCK2;CDC42SE2;GLIPR2;TNFRSF9;TRAF1;BATF;FAH;SLC39A8;ADAM19;WLS;IRF4;PIM1;UMPS;EOMES;RNH1;PTRH2;ITGAE;DHRS3;IGF2R;NDRG1;SNX14;AMACR;IL2RA;IFITM3;SLC1A5;RGS16;CST7;ITGA6;TNFRSF1B;CASP3;AHCY;RHOH;P4HA1;CDKN1C;PRNP;DCPS;LRRC8C;MYO1E;PDCD2L | significant |
| HALLMARK_APOPTOSIS | 0.0000000 | 0.0000000 | 0.7881868 | 0.4177410 | 2.2381121 | 159 | SOD2;CD2;CD38;BIRC3;PAK1;TAP1;ANXA1;CASP1;IL18;CASP4;IL1B;IRF1;SAT1;GPX1;TNFSF10;CD69;CD44;IFNGR1;FASLG;TNF;GADD45A;ISG20;BID;CD14;TNFRSF12A;FAS;NEFH;LMNA;EBP;TSPO;PMAIP1;BTG3;DCN;SQSTM1;HMGB2;TIMP1;TOP2A;PEA15;LUM;WEE1;BAX;MCL1;TIMP2;JUN;CDC25B;GSR;PRF1;PPP2R5B;IGF2R;IGFBP6;TGFB2;GCH1;IFITM3 | significant |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 0.0000000 | 0.0000000 | 0.8140358 | 0.3967533 | 2.2141895 | 195 | MMP1;TAGLN;MMP3;IL32;VCAM1;CAPG;EMP3;ACTA2;CRLF1;CXCL1;IL15;DKK1;PLAUR;TPM1;TGM2;SAT1;FLNA;MYL9;CD44;TPM2;LGALS1;GADD45A;TGFBI;SDC1;MFAP5;TNFRSF12A;FAS;TPM4;SPP1;NNMT;LAMC2;FBLN2;PLOD3;COLGALT1;MYLK;CTHRC1;MCM7;PLOD2;FBLN5;PFN2;DCN;SERPINH1;GLIPR1;TNFRSF11B;TGFB1;COL1A1;VIM;PPIB;TIMP1;WIPF1;SFRP4;LUM;JUN;ITGB1;ID2;FSTL1;FBLN1;COL12A1;FN1;DPYSL3;PLOD1;COL5A2 | significant |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 0.0000318 | 0.0000692 | 0.5573322 | 0.5109090 | 2.1642062 | 47 | SOD2;FTL;PRDX4;PFKP;GLRX;MGST1;PRDX1;PDLIM1;GLRX2;JUNB;TXN;GSR;STK25;SOD1;LSP1;NDUFB4;PRNP;NDUFS2;NDUFA6;HMOX2;FES;PRDX6 | significant |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.0000005 | 0.0000014 | 0.6749629 | 0.3519754 | 1.9412644 | 184 | IDH2;MAOB;MRPL11;LDHA;FH;TCIRG1;MPC1;MRPS22;MRPS15;HSD17B10;ACADM;MGST3;CYB5A;IDH1;SLC25A5;ATP6V1E1;SDHD;UQCRFS1;NDUFS8;SDHB;HTRA2;COX7A2;COX8A;NDUFS3;SLC25A11;NDUFV1;BAX;ETFA;NDUFS1;NDUFA9;TIMM50;TIMM10;IDH3G;POR;TOMM22;COX6B1;MRPL34;ACAA2;PDHX;MDH1;UQCRC1;LDHB;NDUFC2;COX7A2L;MRPL35;OAT;DECR1;UQCRH;SDHA;ETFB;MRPS12;NDUFB5;CYB5R3;NDUFB4;COX5A;NDUFAB1;SUCLG1;NDUFS2;TIMM17A;PRDX3;NDUFA8;NDUFA6;SDHC;MRPS11;NDUFS7;ECH1;GPI;PDHA1;PDP1;ATP6V0E1;NDUFB8;NDUFA3;ALAS1;UQCR10;HADHB | significant |
| HALLMARK_KRAS_SIGNALING_UP | 0.0000005 | 0.0000014 | 0.6594444 | 0.3434095 | 1.8908605 | 191 | CXCL10;SLPI;KCNN4;LAPTM5;BIRC3;CFB;GALNT3;FCER1G;LCP1;IL1B;PLAU;ADAM8;PLAUR;ST6GAL1;MMP11;CD37;IL2RG;IRF8;LY96;PSMB8;IL10RA;CTSS;GFPT2;CXCR4;GLRX;SPP1;CLEC4A;HSD11B1;MMD;TMEM176B;GYPC;ITGB2;MAFB;MMP9;TRIB1;C3AR1;MAP4K1;BPGM;TRAF1;LAT2;PCP4;ADAMDEC1 | significant |
| HALLMARK_COAGULATION | 0.0000083 | 0.0000208 | 0.5933255 | 0.3555445 | 1.8355831 | 137 | MMP1;SERPINA1;MMP7;C1QA;MMP3;CFB;C3;ANXA1;CTSV;APOC2;PLAU;APOC1;PLEK;C1S;A2M;MMP11;CTSB;FGG;SERPING1;C2;C1R;CTSK;PREP;PRSS23;MMP9;CTSH;CPQ | significant |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 0.0002458 | 0.0004552 | 0.4984931 | 0.3534580 | 1.7899478 | 104 | LCK;CDK1;ACTR3;CFL1;EGFR;DAPP1;AP2M1;PFN1;FASLG;SLA;NCK1;IL2RG;GRB2;CXCR4;PPP1CA;RPS6KA3;E2F1;SFN;SQSTM1;PDK1;ACTR2;CSNK2B;PIN1;MAP3K7;MAPK1;CDK4;HSP90B1;CALR;GSK3B;PRKCB;PIK3R3 | significant |
| HALLMARK_UV_RESPONSE_UP | 0.0000124 | 0.0000295 | 0.5933255 | 0.3357573 | 1.7815223 | 154 | SOD2;ICAM1;HLA-F;TUBA4A;TFRC;TAP1;CTSV;RFC4;CCNE1;GGH;IRF1;CHRNA5;FEN1;ARRB2;CCK;LYN;PSMC3;CEBPG;BID;GAL;FOS;ASNS;POLE3;AMD1;STIP1;BTG3;SQSTM1;RPN1;MGAT1;JUNB;AGO2;EPHX1;RAB27A | significant |
| HALLMARK_MITOTIC_SPINDLE | 0.0000168 | 0.0000383 | 0.5756103 | 0.3138429 | 1.7587227 | 197 | CDK1;TUBA4A;KIF2C;TTK;NDC80;FBXO5;MARCKS;FLNA;CCNB2;EZR;BIRC5;NCK1;DLGAP5;CDC42EP1;AURKA;BUB1;SAC3D1;TPX2;VCL;MAP1S;KIF15;BIN1;ECT2;PRC1;ANLN;KIF11;KIF23;CSNK1D;MID1IP1;ARHGAP4;CEP57;CENPE;KATNA1;TUBD1;TOP2A;NUSAP1;EPB41L2;INCENP;MAP3K11;MYH9;DYNLL2;PLK1;SMC4;KIF4A;MAPRE1;TUBGCP2;CDC42EP4 | significant |
| HALLMARK_GLYCOLYSIS | 0.0000608 | 0.0001268 | 0.5573322 | 0.3029159 | 1.6974895 | 197 | B3GNT3;CDK1;DDIT4;CENPA;EGFR;SLC16A3;ME2;CD44;PFKP;KDELR3;ENO1;PKM;LDHA;GALK1;AURKA;TGFBI;SDC1;ISG20;AKR1A1;CXCR4;GLRX;UGP2;GMPPB;ELF3;PSMC4;NASP;PLOD2;ADORA2B;DCN;NSDHL;CHST6;KIF20A;B3GAT1;CYB5A;IDH1;COPB2;B3GAT3;SAP30;KIF2A;PRPS1;TXN;SRD5A3;HAX1;LHPP;MIF;VLDLR;ME1;RPE;GOT1;EXT2;PGAM1;IL13RA1;GUSB;PLOD1;MDH1;TALDO1;SLC25A10;TPI1;CLN6;HMMR;B4GALT4;SOD1;GALK2;P4HA1 | significant |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.0009607 | 0.0016564 | 0.4772708 | 0.3351861 | 1.6879920 | 106 | CCL2;DDIT4;PSAT1;SPCS3;CKS1B;CEBPB;KDELR3;BANF1;CEBPG;MTHFD2;ASNS;PDIA6;EIF4A1;EIF4G1;NABP1;LSM4;POP4;EDEM1;CXXC1;HERPUD1;YIF1A;CHAC1;EXOSC5;SRPRB;ATP6V0D1;TATDN2;EXOSC1;WIPI1;ALDH18A1;HSP90B1;CALR;SEC11A;PREB;DNAJB9;EIF4A2 | significant |
| HALLMARK_DNA_REPAIR | 0.0001867 | 0.0003590 | 0.5188481 | 0.3161046 | 1.6463534 | 145 | ZWINT;RFC4;HCLS1;FEN1;ADRM1;PNP;SAC3D1;POLD3;POLA2;ADA;ALYREF;HPRT1;SF3A3;TYMS;VPS37B;RFC2;UMPS;DDB2;SEC61A1;RFC5;POLR2I;POLR2G;GTF2A2;RBX1;MRPL40;MPC2;EDF1;NELFE;CLP1;GTF2H1;PDE4B;SSRP1;NELFCD;NELFB;POLR2H;GUK1;RPA2;TAF10;POLR3GL;ERCC1;PCNA | significant |
| HALLMARK_APICAL_JUNCTION | 0.0000807 | 0.0001614 | 0.5384341 | 0.2963772 | 1.6379163 | 190 | CDH3;ACTG2;ICAM1;VCAM1;MDK;MSN;EGFR;ZYX;CD99;MYL9;PFN1;TSPAN4;ACTN1;CNN2;MVD;TGFBI;CLDN7;CD274;RAC2;VCL;SYK;LAMC2;ALOX15B;ACTA1;ARPC2;GNAI2;NRTN;SKAP2;CRB3;CX3CL1;MMP9;YWHAH;RRAS;TRAF1;ACTN2;SGCE;ACTB;TNFRSF11B;CAP1;IKBKG;LAMB3;ATP1A3;MYL12B;EPB41L2;MAP4K2;ACTG1;ADAM15;MYH9;ITGB1;ICAM2 | significant |
| HALLMARK_PEROXISOME | 0.0023923 | 0.0038585 | 0.4317077 | 0.3184115 | 1.6124684 | 104 | SOD2;CRABP1;IDH2;FADS1;FDPS;ACSL1;IDI1;SLC25A19;PRDX5;DHCR24;FABP6;ALDH1A1;TSPO;SCGB1A1;PRDX1;YWHAH;ACSL5;ITGB1BP1;IDH1;ELOVL5;MSH2;TOP2A | significant |
| HALLMARK_ANDROGEN_RESPONSE | 0.0064593 | 0.0100927 | 0.4070179 | 0.3108165 | 1.5438743 | 96 | FADS1;FKBP5;SGK1;SAT1;SPCS3;B2M;ADRM1;ACTN1;IDI1;DBI;TNFAIP8;MYL12A;XRCC6;DHCR24;HMGCS1;RPS6KA3;ADAMTS1;LMAN1;UAP1;ELOVL5;CENPN;GSR;NCOA4;SCD;SMS;HOMER2;NDRG1;PDLIM5;UBE2J1;RAB4A;DNAJB9;HMGCR;PGM3;NGLY1;XRCC5 | significant |
| HALLMARK_P53_PATHWAY | 0.0003894 | 0.0006954 | 0.4984931 | 0.2782491 | 1.5320783 | 191 | TM4SF1;CDKN2A;IFI30;TAP1;RAD51C;DDIT4;CASP1;SAT1;KRT17;STEAP3;TCN2;GADD45A;SDC1;CTSD;SOCS1;S100A4;FOS;ST14;FAS;ADA;CD81;DRAM1;ALOX15B;CD82;RPS27L;SFN;TPRKB;UPP1;RHBDF2;CEBPA;PMM1;TGFB1;EPHX1;STOM;IRAK1;BAK1;DDB2;SEC61A1;BAX;DEF6;JUN;PROCR;PRMT2;DCXR;LDHB;NDRG1;VDR;SERPINB5;RCHY1;RGS16;PPP1R15A;GM2A;TAX1BP3;PCNA;RRAD;APP;HMOX1 | significant |
| HALLMARK_HYPOXIA | 0.0014357 | 0.0023928 | 0.4550599 | 0.2634093 | 1.4503685 | 191 | CP;DDIT4;TMEM45A;EGFR;CSRP2;PLAUR;EDN2;TGM2;PFKP;KDELR3;ENO1;PGM1;LDHA;GALK1;TGFBI;ISG20;S100A4;FOS;PFKL;CXCR4;PRDX5;DUSP1;LXN;GLRX;NAGK;UGP2;ZFP36;ADM;ADORA2B;DCN;HS3ST1;PLAC8;SAP30;HEXA;JMJD6;MIF;PIM1;VLDLR;PDK1;GAPDH;JUN;MYH9;SIAH2;SLC25A1;SLC2A5;PNRC1;NDRG1;TPI1;TES;ANXA2;XPNPEP1 | significant |
| HALLMARK_FATTY_ACID_METABOLISM | 0.0097216 | 0.0147297 | 0.3807304 | 0.2604739 | 1.3757508 | 152 | TDO2;IL4I1;ACAT2;ODC1;ACSL1;CBR3;IDI1;LGALS1;LDHA;FH;NCAPH2;DHCR24;HMGCS1;ALDH1A1;UBE2L6;FASN;YWHAH;ACSL5;HSD17B10;NSDHL;ACADM;ADSL;IDH1;SDHD;ELOVL5;EPHX1;MIF;OSTC;ME1;PCBD1;SMS;IDH3G;ACAA2;MDH1;FMO1;DECR1;HIBCH;HADH;SDHA | significant |
| HALLMARK_MYC_TARGETS_V2 | 0.1212121 | 0.1515152 | 0.2712886 | 0.2952492 | 1.2884754 | 57 | MCM5;NIP7;WDR74;SRM;LAS1L;EXOSC5;DUSP2;PLK1;CDK4;HSPE1;PLK4;HSPD1;CBX3;MCM4;RABEPK;BYSL;MPHOSPH10;PRMT3;PPAN;NOP16;PES1;TFB2M | non-significant |
| HALLMARK_ADIPOGENESIS | 0.0176946 | 0.0260215 | 0.3524879 | 0.2315803 | 1.2847700 | 192 | ORM1;C3;DHCR7;IFNGR1;PGM1;MCCC1;GADD45A;CDKN2C;PFKL;ATP1B3;APOE;MYLK;UCP2;DDT;NABP1;ALDH2;ACADM;DNAJC15;JAGN1;MGST3;IDH1;FAH;SAMM50;STOM;SDHB;COQ3;COX8A;NDUFS3;AGPAT3;G3BP2;ME1;TANK;SLC25A1;IDH3G;RNF11;POR;NKIRAS1;ACAA2;TALDO1;UQCRC1;SLC25A10;RTN3;DECR1;SLC1A5;HIBCH;HADH;RAB34;SOD1;UCK1;ETFB;AK2;SLC5A6;DHRS7;PREB;DNAJB9;NDUFAB1;RETN;SUCLG1;STAT5A;PRDX3;ESRRA;SDHC;GHITM;ECH1;DRAM2;UBC;TKT;ESYT1;CHCHD10;CPT2;UQCR10;COQ5 | significant |
| HALLMARK_XENOBIOTIC_METABOLISM | 0.0333006 | 0.0462508 | 0.3217759 | 0.2232335 | 1.2438626 | 194 | TDO2;CFB;PTGDS;CYP27A1;AKR1C3;AQP9;IRF8;GSTO1;COMT;FAS;PTGR1;KYNU;HSD11B1;TMEM176B;PSMB10;XDH;APOE;HPRT1;DDT;PAPSS2;UPP1;ALDH2;PMM1;CYB5A;IDH1;FAH;ARG2;ELOVL5;EPHX1;PGD;ASL;MTHFD1;ID2;HACL1;SAR1B;GSR;FBLN1;HSD17B2;NPC1;CNDP2;POR;DCXR;GART;CES1;FMO1;PDLIM5;TGFB2;GCH1;SLC1A5 | significant |
| HALLMARK_PROTEIN_SECRETION | 0.3439153 | 0.3974706 | 0.1737478 | 0.2097041 | 1.0379759 | 94 | CTSC;EGFR;AP2M1;RAB9A;VAMP7;SGMS1;ARFGAP3;RPS6KA3;COPB2;LMAN1;ANP32E;ADAM10;GLA;SCAMP3;COPE;COPB1;IGF2R;MAPK1;RAB5A;SOD1;VPS4B;STX7;AP2S1;ZW10;ATP1A1;PPT1;YKT6;AP3S1;USO1 | non-significant |
| HALLMARK_HEME_METABOLISM | 0.9953757 | 0.9953757 | 0.0183973 | -0.1379143 | -0.6197966 | 189 | TRIM58;MXI1;HBB;HEBP1;SELENBP1;ALDH1L1;SLC22A4;SLC2A1;HBD;BTRC;NUDT4;TMCC2;RHCE;TAL1;EIF2AK1;SLC6A9;ABCG2;RBM5;TRAK2;SNCA;RHD;FOXJ2;ADD1;AGPAT4;SLC25A38;KHNYN;TNS1;GAPVD1;GDE1;GATA1;SPTA1;RAP1GAP;SLC30A10;EPB41;TCEA1;ERMAP;RNF123;TYR;IGSF3;EZH1;CTSE;RHAG;SMOX;PIGQ;OSBP2;GYPB;SPTB;NFE2;ADD2;DAAM1;CLCN3;MYL4;HAGH;GYPE;PC;ALAS2;AHSP;MKRN1;ANK1;CIR1;SYNJ1;ARHGEF12;BTG2;AQP3;DMTN;EPB42;XPO7;SIDT2 | non-significant |
| HALLMARK_SPERMATOGENESIS | 0.9348613 | 0.9539401 | 0.0246382 | -0.1682433 | -0.7280057 | 132 | PCSK4;SLC12A2;CRISP2;CLGN;GSTM3;JAM3;SHE;TNNI3;CCT6B;ADCYAP1;IFT88;GRM8;PDHA2;TEKT2;GPR182;NPHP1;TNP2;HSPA1L;GAPDHS;PHF7;DDX25;DCC;HTR5A;ZPBP;ARL4A;TSSK2;ODF1;SYCP1;SPATA6;MTNR1A;GSG1;PGK2;SCG3;CLVS1;ALOX15;MLLT10;ACRV1;TNP1;DNAJB8;STRBP;DDX4;HSPA2;NOS1;IL13RA2;CFTR;MAP7;DMC1;ACTL7B;MEP1B;ZC3H14;CCNA1;PRM2;PRKAR2A;BRAF;ZNRF4;RAD17;CHFR;CSNK2A2 | non-significant |
| HALLMARK_ANGIOGENESIS | 0.7210884 | 0.7511338 | 0.0430173 | -0.2394942 | -0.8328412 | 36 | SERPINA5;PDGFA;LPL;PTK2;FGFR1;STC1;VAV2;VEGFA;JAG1;PGLYRP1;POSTN;JAG2;PF4 | non-significant |
| HALLMARK_TGF_BETA_SIGNALING | 0.6126482 | 0.6517534 | 0.0489954 | -0.2441685 | -0.9204016 | 54 | NCOR2;SMAD3;TRIM33;HIPK2;SKI;APC;FNTA;SMURF1;LEFTY2;SERPINE1;BMPR2;THBS1;ID1;FURIN;SMAD1;PPM1A;SMAD6 | non-significant |
| HALLMARK_BILE_ACID_METABOLISM | 0.4698068 | 0.5106595 | 0.0572461 | -0.2337019 | -0.9973925 | 112 | AR;ABCA3;NUDT12;ABCA4;ABCA9;DIO1;ABCA6;PEX6;SLCO1A2;RXRA;AGXT;ABCG8;EPHX2;LONP2;ABCA8;PEX12;LIPE;ABCA5;NR3C2;EFHC1;HSD17B4;ALDH8A1;PEX19;NR1I2;SLC23A1;CYP46A1;SLC27A2;AKR1D1;CYP7A1;HAO1;PHYH;PFKM;NR1H4;ABCA2;ISOC1;FDXR;SULT1B1;SLC23A2 | non-significant |
| HALLMARK_APICAL_SURFACE | 0.3577236 | 0.3974706 | 0.0762797 | -0.3018782 | -1.0894231 | 43 | GATA3;ADIPOR2;SHROOM2;TMEM8B;EFNA5;MDGA1;BRCA1;GSTM3;SULF2 | non-significant |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 0.3550136 | 0.3974706 | 0.0766747 | -0.3051342 | -1.0930656 | 42 | HEY1;HEY2;NCOR2;DLL1;NOTCH4;DKK4;WNT5B;TP53;FRAT1;JAG1;NKD1;AXIN2;HDAC11;JAG2;KAT2A;FZD1;PTCH1;HDAC5;FZD8 | non-significant |
| HALLMARK_UV_RESPONSE_DN | 0.1857143 | 0.2264808 | 0.1063233 | -0.2705439 | -1.1769821 | 138 | IGF1R;KIT;IRS1;CDON;MMP16;ICA1;APBB2;SMAD3;RXRA;SCN8A;ITGB3;MAGI2;AMPH;ATP2B4;DBP;CDK13;ZMIZ1;ATRN;VAV2;DLC1;SERPINE1;MIOS;MAP2K5;SYNJ2;INPP4B;SNAI2;PDGFRB;ATRX;RGS4;TGFBR3;BDNF;PRKCE;ID1;ERBB2;YTHDC1;PRKAR2B;CDKN1B;PIAS3;MT1E;PTPRM;AGGF1;SCAF8;RBPMS;RUNX1 | non-significant |
| HALLMARK_NOTCH_SIGNALING | 0.2492997 | 0.2967854 | 0.0982123 | -0.3516182 | -1.1792838 | 32 | CCND1;HEYL;DLL1;TCF7L2;JAG1;DTX1;DTX4;HES1;KAT2A;FZD7;FBXW11;NOTCH3;FZD1 | non-significant |
| HALLMARK_MYOGENESIS | 0.1196778 | 0.1515152 | 0.1342735 | -0.2650694 | -1.1951625 | 196 | CACNA1H;STC2;PPP1R3C;CAMK2B;PGAM2;CACNG1;TNNT3;PPFIA4;ERBB3;LAMA2;BAG1;ADCY9;SGCG;CKMT2;PVALB;MYL7;CD36;HSPB8;ITGA7;MYOM2;MYOM1 | non-significant |
| HALLMARK_KRAS_SIGNALING_DN | 0.0260946 | 0.0372780 | 0.3524879 | -0.3050985 | -1.3739872 | 191 | ADRA2C;KRT1;CACNG1;IGFBP2;TFAP2B;CPB1;CELSR2;GAMT;COL2A1;CAPN9;FGFR3;NR4A2;LGALS7;RGS11;CCDC106;RYR2;KMT2D;TENM2;PAX3;CPEB3;KLK7;GPRC5C;ARPP21;ATP6V1B1;TNNI3;BMPR1B;NRIP2;GP2;DLK2;TFF2;CLSTN3;CDH16;CNTFR;KCNE2;IDUA;NUDT11;ITIH3;KLHDC8A;IRS4;MYH7;MYOT;EGF;SIDT1;DCC;INSL5;WNT16;VPREB1;NGB;SHOX2;MTHFR;KRT15;CHRNG;THNSL2;PNMT;PDK2;CPA2;FSHB;HTR1B;SCN10A;CYP11B2;HTR1D;SNCB;EPHA5;TEX15;NTF3;CD40LG;SERPINB2;NOS1;TAS2R4;GRID2;KCND1;ABCG4;TSHB;MAGIX;BRDT;MYO15A;P2RX6;SLC12A3;CCNA1;EFHD1;ARHGDIG;ZNF112;ABCB11;AMBN;PRODH;SERPINA10;ATP4A;IL5;BTG2;NPHS1;FGF16;FGF22;SLC16A7;CACNA1F;UGT2B17;YBX2 | significant |
| HALLMARK_PANCREAS_BETA_CELLS | 0.0568336 | 0.0747810 | 0.2192503 | -0.4020887 | -1.4315647 | 40 | SYT13;CHGA;PCSK1;ABCC8;SCGN;STXBP1;NKX2-2;ISL1;INSM1;PAK3;NEUROD1;SLC2A2;PDX1 | non-significant |
| HALLMARK_HEDGEHOG_SIGNALING | 0.0487805 | 0.0659196 | 0.2377938 | -0.4248349 | -1.4683850 | 35 | HEY1;HEY2;NRCAM;CRMP1;GLI1;CNTFR;SCG2;SLIT1;TLE3;CELSR1;VEGFA;CDK6;PLG;UNC5C;PTCH1;OPHN1;ETS2;RASA1;L1CAM;NKX6-1;CDK5R1;LDB1 | non-significant |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 0.0000009 | 0.0000023 | 0.6594444 | -0.4124218 | -1.8565881 | 192 | TFF1;TFF3;SCUBE2;CA12;NPY1R;ANXA9;DHRS2;CACNA2D2;PDZK1;MEST;AGR2;DNAJC12;CCND1;SLC22A5;SLC24A3;ASCL1;MAPT;MYB;IL17RB;GPER1;CELSR2;SERPINA5;ABCA3;PDCD4;PTGES;FGFR3;BAG1;ACOX2;KLK10;RET;FLNB;HSPB8;TPSAB1;NCOR2;EGR3;PTGER3;PGR;HMGCS2;BCL2;NRIP1;KLK11;RAPGEFL1;CISH | significant |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 0.0000000 | 0.0000000 | 1.0476265 | -0.5325451 | -2.3954994 | 190 | TFF1;TFF3;SLC7A2;CA12;NPY1R;ANXA9;DHRS2;ELOVL2;SLC19A2;THSD4;PDZK1;STC2;GFRA1;MSMB;CCND1;IGF1R;SLC39A6;TUBB2B;SLC22A5;MLPH;AR;SLC24A3;MAPT;SYT12;ADCY1;MYB;ABAT;IL17RB;CELSR2;CBFA2T3;ABCA3;MAST4;PTGES;BAG1;RHOBTB3;KLK10;RET;ADCY9;FLNB;HSPB8;NCOR2;EGR3;INHBB;SYBU;SLC1A1;PGR;MED13L;BCL2;GREB1;SLC2A1;NRIP1;RAPGEFL1;CISH;KCNK15;REEP1;PODXL;KAZN;WWC1;MPPED2;OLFM1;ABHD2;KRT18;SOX3;AREG | significant |
| | | 0% | |==== | 6% | |======== | 11% | |============ | 17% | |================ | 22% | |=================== | 28% | |======================= | 33% | |=========================== | 39% | |=============================== | 44% | |=================================== | 50% | |======================================= | 56% | |=========================================== | 61% | |=============================================== | 67% | |=================================================== | 72% | |====================================================== | 78% | |========================================================== | 83% | |============================================================== | 89% | |================================================================== | 94% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 0.0000000 | 0.0000000 | 1.7026781 | 0.7740876 | 3.1181767 | 194 | CXCL9;IDO1;CD38;SLAMF7;CXCL10;CCL5;CXCL11;GZMA;TAP1;IL2RB;SOD2;GBP4;BATF2;IRF4;PFKP;ISG20;ICAM1;STAT1;PSMB9;CCL2;BANK1;XCL1;HLA-DRB1;SOCS1;IRF1;IL10RA;CCL7;IFI30;ZBP1;CD74;LCP2;VCAM1;HLA-A;HLA-DMA;PIM1;ITGB7;HLA-DQA1;GPR18;HLA-B;SERPING1;PNP;CD69;CD274;FGL2;CASP1;USP18;OASL;IFIH1;VAMP5;EPSTI1;FPR1;SAMD9L;C1S;SECTM1;CIITA;APOL6;IL15;CD40;TNFAIP2;P2RY14;RTP4;TNFAIP3;CASP4;IRF8;IL15RA;IL18BP;PSMB8;CMKLR1;IFI44L;TNFSF10;B2M;MX2;NMI;MTHFD2;RSAD2;GCH1;PELI1;C1R;MX1;PSMB10;IL6;NLRC5;OAS2;UBE2L6;IRF5;XAF1;UPP1;HLA-G;PARP12;CFH;IFI44;FAS;IFNAR2;IL7;IFIT3;NAMPT;PML;LAP3;NUP93;MT2A;JAK2;RIPK2;PDE4B;LY6E;ST3GAL5;STAT4;PSMB2;KLRK1;MYD88;PLSCR1;HIF1A;IFI27;STAT2;IL4R;PSME2;SOCS3;BST2;PTGS2;LYSMD2;CASP3;NFKBIA;PARP14;TRIM14;PLA2G4A;IFIT2 | significant |
| HALLMARK_ALLOGRAFT_REJECTION | 0.0000000 | 0.0000000 | 1.6533146 | 0.7639199 | 3.0792906 | 195 | CXCL9;CXCL13;GZMB;CCL13;CCL5;CD2;CD79A;CD3D;LTB;GZMA;CCL4;TAP1;LCK;IL2RB;CD3G;IRF4;CXCR3;CD247;CDKN2A;CCR5;ICAM1;STAT1;MMP9;CCL19;HLA-DRA;CCL2;CD8A;FASLG;IFNG;ZAP70;HCLS1;SOCS1;SIT1;CD96;CCL7;HLA-E;CD74;C2;IL2RG;LCP2;HLA-A;HLA-DMA;HLA-DQA1;LYN;CCR2;HLA-DOB;GCNT1;IL18RAP;TLR2;SRGN;GBP2;IL2RA;PRKCB;CTSS;IL27RA;CD8B;FCGR2B;IL1B;TRAT1;CFP;IL15;CD40;ITK;TNF;NCF4;PRF1;IRF8;FGR;CD7;CCR1;IL18;CRTAM;LY75;ITGAL;TLR1;B2M;ITGB2;PTPRC;CCND2;HLA-DMB;IGSF6;PSMB10;IL6;IFNGR1;HLA-DOA;HLA-G;MAP4K1;CAPG;CD47;FAS;KLRD1;IFNAR2;CCL11;ETS1;IL7;CD28;WAS;JAK2;RIPK2;GPR65;CSK;STAT4;IL10;IL16;HIF1A;IL4R;TLR6;TAP2;IFNGR2;NCK1;CD40LG;UBE2D1;LY86;ELF4;CCND3;EIF5A | significant |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 0.0000000 | 0.0000000 | 1.0768682 | 0.7463659 | 2.7754146 | 94 | LAMP3;CXCL10;CXCL11;TAP1;GBP4;BATF2;ISG20;PSMB9;IRF1;IFI30;CD74;HLA-C;GBP2;CASP1;USP18;OASL;IFIH1;EPSTI1;NCOA7;SAMD9L;C1S;IL15;RTP4;PSMB8;IFI44L;B2M;NMI;RSAD2;MX1;UBE2L6;PARP12;CD47;IFI44;SELL;IL7;IFIT3;LAP3;OAS1;RIPK2;LY6E;PLSCR1;IFI27;STAT2;IL4R;PSME2;TMEM140;BST2;CCRL2;PARP14;TRIM14;IFIT2;SLC25A28;TRIM21;NUB1 | significant |
| HALLMARK_INFLAMMATORY_RESPONSE | 0.0000000 | 0.0000000 | 1.2125446 | 0.6608781 | 2.6751422 | 197 | CXCL9;LAMP3;CXCL10;MARCO;CCL5;CXCL11;CCR7;LCK;IL2RB;CCL17;CXCR6;ICAM1;CCL2;CD70;IRF1;IL10RA;CCL7;SLAMF1;CYBB;CD48;GPR183;LCP2;IL7R;LYN;IL18RAP;TLR2;ADM;EBI3;CD69;AQP9;CHST2;IL1B;CD14;FPR1;EDN1;PLAUR;PTGER4;RGS1;OSM;IL15;CD40;RNF144B;RTP4;PTAFR;IL15RA;CD82;IL18;CMKLR1;SLC31A2;TNFSF10;TLR1;ICAM4;TNFRSF9;NMI;GCH1;CCL20;IL6;CX3CL1;EMP3;SLC31A1;SELL;KCNJ2;C3AR1;SLC7A1;NAMPT;ADORA2B;RGS16;NOD2;GPR132;RIPK2;PDE4B;LY6E;KCNA3;MET;IL10;TNFRSF1B;HIF1A;PDPN;RASGRP1;IL4R;IFNGR2;BST2;CCRL2;RHOG;GP1BA;PTGIR;NFKBIA | significant |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.0000000 | 0.0000000 | 0.9865463 | 0.7209242 | 2.6414905 | 87 | CXCL9;CXCL13;CD38;CXCL10;CXCL11;LTB;STAT1;CXCL1;SOCS1;IRF1;CCL7;IL2RG;PIM1;TNFRSF21;TLR2;EBI3;IL2RA;IL1B;CD14;TNF;IL15RA;CCR1;IL6;IFNGR1;BAK1;CD44;IL17RA;IL3RA;FAS;CSF2RA;PLA2G2A;IL7;MAP3K8;MYD88;TNFRSF1B;STAT2;IL4R;IFNGR2;SOCS3;IL1R2;ITGA4;A2M;IL12RB1;IL10RB;CBL;PTPN2 | significant |
| HALLMARK_E2F_TARGETS | 0.0000000 | 0.0000000 | 1.0376962 | 0.6059830 | 2.4426614 | 195 | CDKN2A;CCNE1;MELK;EZH2;TFRC;KIF2C;DLGAP5;CDC20;MYBL2;DEK;NASP;HMGB3;CDC25B;CHEK1;MCM2;MCM5;PTTG1;LBR;MCM6;DONSON;MCM3;HMGA1;MCM4;MTHFD2;CDCA8;TOP2A;SPAG5;ANP32E;STMN1;LMNB1;TUBB;AURKA;KIF4A;KPNA2;MMS22L;CDK1;CTPS1;CCNB2;RRM2;CDKN3;ORC6;BIRC5;NCAPD2;CDCA3;MCM7;PRDX4;SPC25;SYNCRIP;RANBP1;RAD51AP1;HMMR;DSCC1;ASF1A;NUP153;AURKB;CENPE;CDC25A;TRIP13;SMC6;CKS1B;MAD2L1;PLK1;SNRPB;PCNA;SMC4;UBE2T;NUP205;DDX39A;TACC3;CKS2;MKI67;CHEK2;DNMT1;DIAPH3;ZW10;TCF19;CENPM;SSRP1;USP1;E2F8;PRIM2;HELLS;XRCC6;RFC2;RNASEH2A;HMGB2;DEPDC1;LYAR;KIF18B;MSH2;EXOSC8;TRA2B;GINS1;BUB1B;RAD1;ATAD2;RAN;POLA2;LIG1;CIT;RFC3;RPA2;ASF1B;NUDT21;POLD1;NOLC1;SRSF2;RPA1;NME1;WEE1;BRMS1L;CDKN1A | significant |
| HALLMARK_COMPLEMENT | 0.0000000 | 0.0000000 | 1.0376962 | 0.6004412 | 2.4389806 | 198 | S100A9;GZMB;CCL5;GZMA;GZMK;LCK;CXCL1;KYNU;C1QA;PSMB9;PLA2G7;LTF;IRF1;PLEK;CTSV;C1QC;CTSC;C2;CP;LCP2;PIM1;LYN;APOBEC3G;SPOCK2;SERPING1;CASP1;CTSS;CEBPB;C1S;PLAUR;CTSH;FCN1;FCER1G;CTSL;TNFAIP3;CASP5;FYN;C3;CASP4;DUSP6;APOC1;PFN1;LGMN;ITGAM;C1R;CASP10;IL6;PREP;GNB4;CFH;CTSB;APOBEC3F;COL4A2;PIK3CG;GNGT2;CR2;LAP3;S100A12;CPM;WAS;JAK2;EHD1;PLSCR1;ME1;PCSK9;XPNPEP1;RASGRP1;PHEX;LGALS3;KIF2A;MAFF;CD40LG;PDP1;RHOG;GP1BA;CASP3 | significant |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.0000000 | 0.0000000 | 1.0073180 | 0.6004493 | 2.4305348 | 197 | CXCL10;CCL5;CXCL11;CCL4;TAP1;SOD2;ICAM1;CXCL1;KYNU;CCL2;BIRC3;IRF1;PLEK;GPR183;NFIL3;IL7R;CD83;TLR2;CD69;TNFAIP8;EGR2;IFIH1;IL1B;TRAF1;CEBPB;EDN1;PLAUR;PTGER4;NFKBIE;TNFAIP2;BCL2A1;RCAN1;TNF;TNFAIP3;IL15RA;IL18;IL23A;RELB;PLAU;TNFRSF9;B4GALT5;GCH1;CCL20;DUSP2;PNRC1;SGK1;IL6;VEGFA;CFLAR;CD44;BTG3;STAT5A;MARCKS;ZFP36;ZC3H12A;NAMPT;MAP3K8;SAT1;EHD1;RIPK2;SLC2A6;PDE4B;TRIB1;SNN;FUT4;CXCL2;DRAM1;GADD45A;TANK;G0S2;IFNGR2;LITAF;MAFF;SPSB1;MCL1;SOCS3;PTX3;ID2;PTGS2;CCRL2;TUBB2A;SERPINB8;NFKBIA;GFPT2;IFIT2;JUNB;DUSP4;NFKB1;SIK1;MAP2K3;ATF3;NR4A3;BTG1;TNFSF9;SLC2A3;NFKB2;SPHK1;PHLDA2;ETS2;CD80;TNIP1;LDLR;CCNL1;TRIP10;ICOSLG;B4GALT1 | significant |
| HALLMARK_G2M_CHECKPOINT | 0.0000000 | 0.0000000 | 0.9101197 | 0.5726103 | 2.2977586 | 188 | SLC7A5;EZH2;CENPA;CDC45;KIF2C;TTK;CDC20;MYBL2;NASP;HMGB3;BUB1;ODC1;CDC25B;CHEK1;MCM2;MCM5;PTTG1;LBR;TPX2;MCM6;EXO1;MCM3;HMGA1;UCK2;NDC80;E2F3;CCNA2;TOP2A;E2F2;UBE2C;STMN1;LMNB1;AURKA;KIF4A;KPNA2;MARCKS;RAD54L;SLC7A1;AMD1;CDK1;KIF11;TFDP1;PML;CCNB2;CDKN3;ORC6;BIRC5;MT2A;SYNCRIP;E2F1;CUL1;NUP50;HMMR;INCENP;SAP30;CENPF;HIF1A;AURKB;CENPE;CDC25A;CKS1B;FBXO5;MAD2L1;PLK1;SMC4;DDX39A;TACC3;CKS2;MKI67;CDC7;POLQ;FANCC;PRIM2;KIF23;KIF15;CDC6;PRC1;KATNA1;TROAP;SQLE;TRA2B;HIRA;GINS2;POLA2;DKC1;FOXN3;RPA2;CHAF1A;HSPA8;SMC2;E2F4 | significant |
| HALLMARK_IL2_STAT5_SIGNALING | 0.0000000 | 0.0000000 | 0.8140358 | 0.5241944 | 2.1115579 | 194 | CXCL10;LTB;IL2RB;ICOS;GBP4;IRF4;CCNE1;SOCS1;CD79B;IL10RA;CD48;TNFRSF8;PIM1;NFIL3;EOMES;TNFRSF21;CD83;GLIPR2;PNP;IL2RA;FGL2;TNFRSF4;BATF3;TRAF1;ODC1;PLIN2;IRF8;CST7;ITGA6;CTLA4;TNFSF10;COCH;UCK2;TNFRSF9;CCND2;RRAGD;BATF;ADAM19;CKAP4;IFNGR1;CD44;IGF2R;CAPG;SELL;IL3RA;CTSZ;NDRG1;MAP3K8;RGS16;GPR65;LRRC8C;IL10;PRKCH;SMPDL3A;TNFRSF1B;PLSCR1;TIAM1;TTC39B;IL4R;GALM;ETV4;DCPS;MAFF;S100A1;TGM2;NCS1;IL1R2;CASP3;CDC42SE2;CCND3;NT5E;CDCP1;CDC6 | significant |
| HALLMARK_KRAS_SIGNALING_UP | 0.0000000 | 0.0000001 | 0.7337620 | 0.4978637 | 1.9992857 | 191 | CXCL10;SLPI;MYCN;MMP9;ST6GAL1;ADAMDEC1;LCP1;BIRC3;HSD11B1;IL10RA;KCNN4;IL2RG;TMEM176B;IL7R;TMEM176A;LAPTM5;GPRC5B;CTSS;CXCR4;IL1B;TRAF1;CD37;PLAUR;GALNT3;MPZL2;FCER1G;CLEC4A;ADAM8;GLRX;TNFAIP3;IRF8;PSMB8;DUSP6;CMKLR1;TLR8;ITGB2;PLAU;IKZF1;CCND2;CCL20;MALL;PRDM1;PCP4;LY96;MAP4K1;CFH;C3AR1;CSF2RA;ETS1;ALDH1A3;RGS16;SOX9;TMEM158;SATB1;TRIB1;TNFRSF1B;GPNMB;LAT2;G0S2;ETV4;ID2;PTGS2;GYPC;APOD;GFPT2;F13A1;CBL;DOCK2;IGFBP3;MAFB;EPHB2 | significant |
| HALLMARK_MTORC1_SIGNALING | 0.0000001 | 0.0000004 | 0.6901325 | 0.4855135 | 1.9557437 | 194 | PSAT1;PHGDH;DAPP1;CORO1A;IFI30;SLC7A5;CTSC;PDK1;TFRC;NFIL3;SLA;PNP;FGL2;FADS2;GMPS;CXCR4;BUB1;CFP;GLRX;MCM2;DDIT4;ASNS;ITGB2;MCM4;MTHFD2;LGMN;SCD;IFRD1;VLDLR;TES;AURKA;ENO1;NAMPT;ACTR3;DHCR7;AK4;RRM2;ARPC5L;PSMG1;TUBA4A;PGM1;SRD5A1;PSPH;ME1;PITPNB;NFKBIB;CDC25A;SHMT2;EDEM1;PLK1;SDF2L1;IDI1;NUP205;DDX39A;PPA1;HSP90B1;ACTR2;RPN1;STARD4;IDH1;HMBS;BCAT1;TOMM40;CALR;MAP2K3;HMGCS1;SQLE;SLC2A3;PSMA3;EGLN3;SLC37A4;SSR1;PSMB5;PSMA4;SLC1A5;LDLR | significant |
| HALLMARK_MYC_TARGETS_V1 | 0.0000312 | 0.0001038 | 0.5573322 | 0.4301847 | 1.7300491 | 193 | PSMD3;CDC45;CDC20;DEK;PSMB3;ODC1;MCM2;MCM5;MCM6;MCM4;CCNA2;HDAC2;IFRD1;SRPK1;RFC4;ILF2;KPNA2;CTPS1;TFDP1;TYMS;MCM7;PRDX4;SYNCRIP;PSMB2;CUL1;RANBP1;FBL;YWHAQ;PPM1G;MAD2L1;PCNA;SERBP1;HDGF;EIF4A1;MRPL9;U2AF1;USP1;XRCC6;SF3B3;PABPC1;SNRPA;SNRPA1;LSM2;STARD7;GLO1;TRA2B;SNRPD3;NCBP1;PSMA4;TCP1;RAN;CAD;COX5A;PSMD7;UBE2L3;PSMD14;NOLC1;SRSF2;NME1;SET;ABCE1;SRSF3;APEX1;CCT4;EIF3D;SNRPG;PGK1;SMARCC1;SRM;PSMA7;CSTF2;POLE3;CCT3;PSMC4;CCT7 | significant |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 0.0069107 | 0.0172767 | 0.4070179 | 0.4555703 | 1.6053466 | 72 | CBS;NFIL3;FADS2;S100A11;PLAUR;GLDC;LGMN;PNRC1;SCD;CXCL16;SREBF2;DHCR7;FABP5;ACAT2;PLSCR1;FDPS;IDI1;MVD;LPL;LGALS3;FBXO6;STARD4;HMGCS1;ATF3;SQLE | significant |
| HALLMARK_APOPTOSIS | 0.0038891 | 0.0114385 | 0.4317077 | 0.3842947 | 1.5170016 | 159 | CD38;CD2;TAP1;SOD2;ISG20;FASLG;BIRC3;IRF1;ERBB2;CD69;CASP1;IL1B;CD14;TNF;CDC25B;PRF1;CASP4;IL18;TNFSF10;CCND2;GCH1;TOP2A;IL6;IFNGR1;BID;CFLAR;CD44;IGF2R;BTG3;FAS;SAT1;PLCB2;TSPO;SATB1;ANXA1;GADD45A;GSN;LGALS3;MCL1 | significant |
| HALLMARK_MITOTIC_SPINDLE | 0.0023475 | 0.0073358 | 0.4317077 | 0.3721431 | 1.5063835 | 197 | KIF2C;DLGAP5;TTK;BUB1;CDC42EP1;TPX2;NDC80;TOP2A;ANLN;PIF1;LMNB1;AURKA;KIF4A;MARCKS;ARHGAP4;CDK1;KIF11;CCNB2;BIRC5;TUBA4A;BIN1;INCENP;CENPF;MID1;TIAM1;CENPE;FBXO5;GSN;SUN2;PLK1;NCK1;EPB41L2;ARHGAP10;SMC4;ARHGAP27;KNTC1;ECT2;ARHGEF2;KIF23;ACTN4;KIF15;DOCK2;GEMIN4;PRC1;KATNA1;NCK2;CAPZB;MYH9;FLNA;SSH2;ABI1;TUBGCP3;MYO9B;WASF1;NEDD9;DYNC1H1;RANBP9;PLEKHG2;MYO1E;RASA2;DLG1;RASAL2;ARHGEF3;SORBS2;RHOF;AKAP13;PAFAH1B1;NOTCH2;FSCN1;BRCA2;CNTRL;VCL;CSNK1D;TUBD1;SMC3;OPHN1;CKAP5;CDK5RAP2;CENPJ;KIF1B;CCDC88A;DYNLL2;ARHGEF7 | significant |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.0099297 | 0.0207070 | 0.3807304 | 0.3984386 | 1.4944447 | 106 | PSAT1;CCL2;SLC7A5;SPCS3;CEBPB;DDIT4;HERPUD1;ASNS;MTHFD2;VEGFA;NABP1;PDIA6;ATF4;PDIA5;CKS1B;EDEM1;DNAJB9;CHAC1;EIF4G1;HSP90B1;EIF4A1;TUBB2A;HYOU1;TATDN2;GEMIN4;KDELR3;CALR;ATF3;PREB | significant |
| HALLMARK_COAGULATION | 0.0055260 | 0.0153500 | 0.4070179 | 0.3824835 | 1.4825025 | 137 | MMP1;KLK8;MMP9;C1QA;MMP7;MMP3;PLEK;CTSV;C2;SERPING1;C1S;CTSH;SH2B2;FYN;C3;DUSP6;APOC1;PLAU;LGMN;C1R;PREP;CFH;CTSB;APOC2;FGG;ANXA1;GSN;MAFF;S100A1 | significant |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 0.0188121 | 0.0348372 | 0.3524879 | 0.3896067 | 1.4612819 | 104 | LCK;DAPP1;FASLG;PDK1;IL2RG;SLA;PRKCB;CXCR4;PFN1;MAPK1;CDK1;ACTR3;RPS6KA3;E2F1;MYD88;NFKBIB;TIAM1;STAT2;NCK1;HSP90B1;ACTR2;CALR;MAP2K3;MAP3K7;CFL1;NOD1;TRAF2;PAK4 | significant |
| HALLMARK_APICAL_JUNCTION | 0.0099394 | 0.0207070 | 0.3807304 | 0.3563929 | 1.4327358 | 190 | GRB7;CDH3;ICAM1;MMP9;ACTG2;SYK;VCAM1;CD274;MDK;TRAF1;RAC2;MPZL2;NRTN;MSN;CALB2;ICAM2;PTPRC;ICAM4;PFN1;CX3CL1;CNN2;RSU1;SIRPA;LAMC2;ITGB4;TGFBI;SLC30A3;MVD;EPB41L2;ITGA9;ZYX;CD209;VASP;CDH1;MPZL1;CLDN4;COL9A1;ALOX15B;ADAM15;CLDN14;CAP1;ACTN4;ACTB;CD99;ATP1A3;MYH9;CLDN6;MAPK13;ARPC2;CDSN;ACTN1 | significant |
| HALLMARK_HYPOXIA | 0.0076777 | 0.0182802 | 0.4070179 | 0.3509076 | 1.4091501 | 191 | PFKP;ISG20;TMEM45A;CP;PDK1;PIM1;PLAC8;NFIL3;CSRP2;ADM;CHST2;LDHC;CXCR4;PLAUR;GLRX;PLIN2;TNFAIP3;DDIT4;RRAGD;PNRC1;IL6;VEGFA;EDN2;VLDLR;TES;SLC2A5;S100A4;ENO1;ZFP36;NDRG1;ETS1;AK4;ADORA2B;MT2A;PGM1;TPST2;NAGK;SAP30;XPNPEP1;TGFBI;UGP2;KLHL24;MAFF;TGM2;TKTL1;AMPD3;HEXA;FOXO3;IGFBP3;KDELR3;PKP1;ATF3;BTG1;MYH9;GCNT2;CDKN1C;SLC2A3;LALBA;EXT1;SLC37A4 | significant |
| HALLMARK_UV_RESPONSE_UP | 0.0132156 | 0.0254146 | 0.3807304 | 0.3583953 | 1.4083896 | 154 | TAP1;SOD2;ICAM1;STARD3;HLA-F;GAL;CCNE1;IRF1;CTSV;TFRC;LYN;GGH;ASNS;CHRNA5;GCH1;FMO1;IL6;RFC4;BID;BAK1;LHX2;BTG3;MGAT1;CCK;AMD1;FEN1;TUBA4A;ARRB2;CXCL2;RASGRP1;RAB27A;AGO2;PARP2;CASP3;CCND3;NFKBIA;RPN1;SIGMAR1;JUNB;ALAS1;KLHDC3;PPIF;ATF3;PRPF3;BTG1;CREG1;CDKN1C;EPCAM;CNP | significant |
| HALLMARK_KRAS_SIGNALING_DN | 0.0098712 | 0.0207070 | 0.3807304 | 0.3461697 | 1.3901238 | 191 | CALML5;KLK8;PNMT;TCL1A;PDCD1;IFNG;SLC6A14;SOX10;LGALS7;KRT5;CHST2;KRT15;TCF7L1;EDN1;KLK7;IFI44L;KRT4;PRODH;GPR19;CAMK1D;RSAD2;MX1;RYR1;AKR1B10;SGK1;EDN2;TFF2;TGM1;SCGB1A1;GTF3C5;SNN;YPEL1;TFAP2B;SLC30A3;KCNMB1;CDKAL1;CD40LG;STAG3;GP1BA;PLAG1;KRT13;MYH7;YBX2;PKP1 | significant |
| HALLMARK_P53_PATHWAY | 0.0122110 | 0.0244221 | 0.3807304 | 0.3409447 | 1.3691417 | 191 | KLK8;TAP1;KRT17;CDKN2A;SOCS1;CLCA2;IFI30;PERP;TM4SF1;SDC1;CASP1;DDIT4;RHBDF2;TCN2;CD82;CCND2;ST14;LDHB;ADA;BAK1;UPP1;S100A4;FAS;NDRG1;SAT1;TPD52L1;STEAP3;RGS16;GM2A;SERPINB5;ITGB4;DRAM1;GADD45A;PCNA;S100A10;NOTCH1;DEF6;APP;CCND3;CEBPA;VDR;ALOX15B;FBXW7;FOXO3;ATF3;CDK5R1;BTG1;PLK3;SEC61A1;TNFSF9;RPS12 | significant |
| HALLMARK_MYC_TARGETS_V2 | 0.1054767 | 0.1573351 | 0.1957890 | 0.3837853 | 1.3026431 | 57 | MCM5;MCM4;DUSP2;BYSL;PLK1;PUS1;PPAN;PPRC1;NDUFAF4;RCL1;NIP7;NOP2;MYBBP1A;NOLC1;PES1;SLC19A1;SRM;LAS1L;PLK4;CDK4;TCOF1;NOP56;SUPV3L1;MAP3K6;NOP16 | non-significant |
| HALLMARK_GLYCOLYSIS | 0.0689655 | 0.1102571 | 0.2377938 | 0.3113954 | 1.2604851 | 197 | B3GNT3;PFKP;ISG20;CENPA;SDC1;CHST2;LDHC;CXCR4;SPAG4;NASP;MED24;GLRX;DDIT4;KIF20A;RRAGD;DSC2;B3GAT1;SLC16A3;VEGFA;VLDLR;CHST6;STMN1;CD44;AURKA;ENO1;CDK1;AK4;ADORA2B;SOX9;MET;HMMR;ME1;SAP30;TGFBI;UGP2;CHST4;KIF2A;AKR1A1;PLOD1;TKTL1;PYGB;IDH1;NT5E;IGFBP3;KDELR3;CHST12;DEPDC1;SDHC;EGLN3;ME2;PGAM1;EXT1;SLC37A4 | non-significant |
| HALLMARK_SPERMATOGENESIS | 0.1318898 | 0.1735392 | 0.1709323 | 0.3164719 | 1.2239144 | 132 | IL12RB2;ART3;EZH2;KIF2C;DPEP3;TTK;LDHC;POMC;BUB1;CRISP2;GFI1;LPIN1;RFC4;SLC2A5;RPL39L;AURKA;CDK1;CCNB2;CDKN3;PSMG1;AGFG1;PARP2;TKTL1;NCAPH;YBX2;CHRM4 | non-significant |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 0.1132812 | 0.1573351 | 0.1847065 | 0.2974432 | 1.1989660 | 195 | MMP1;DKK1;IL32;CXCL1;MMP3;SFRP1;VCAM1;SDC1;PLAUR;IL15;TNFAIP3;WIPF1;FBLN2;IL6;VEGFA;EMP3;CD44;TPM4;CAPG;COL4A2;FBLN5;FAS;GAS1;SAT1;MCM7;LAMC2;SERPINE2;GADD45A;COLGALT1;TGFBI;NNMT;PTX3;TGM2;ID2;GPX7;PLOD1;PPIB;CTHRC1;CALU;MFAP5;NT5E;PFN2 | non-significant |
| HALLMARK_APICAL_SURFACE | 0.2152642 | 0.2690802 | 0.1301056 | 0.3649624 | 1.1809847 | 43 | IL2RB;GHRL;MAL;IL2RG;LYN;ATP6V0A4;PLAUR;CX3CL1;RHCG;GAS1;PCSK9;AKAP7;APP | non-significant |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 0.2345679 | 0.2860584 | 0.1275053 | 0.3516431 | 1.1447244 | 47 | SOD2;PFKP;GLRX;PRDX4;FTL;PDLIM1;LSP1;JUNB;MGST1;FES;NDUFA6;GPX3 | non-significant |
| HALLMARK_XENOBIOTIC_METABOLISM | 0.3431373 | 0.4084967 | 0.0992333 | 0.2586756 | 1.0419959 | 194 | HSD17B2;PTGDS;TDO2;KYNU;HSD11B1;TMEM176B;AQP9;ALDH2;IRF8;DDC;PAPSS2;NDRG2;GCH1;FMO1;PSMB10;XDH;ABCC3;UPP1;APOE;VNN1;FAS;CES1;COMT;MT2A;SMOX;CYP27A1;GSTA3;SLC35B1;MAN1A1;SHMT2;ID2;PGD;ABCC2;IDH1;NPC1;POR;BCAT1;ALAS1;PGRMC1 | non-significant |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 0.3843058 | 0.4468673 | 0.0940503 | 0.3215755 | 1.0260781 | 42 | WNT6;DKK1;CCND2;HDAC2;CUL1;WNT5B;SKP2;TCF7;NOTCH1;NCSTN;ADAM17;PPARD | non-significant |
| HALLMARK_TGF_BETA_SIGNALING | 0.8941176 | 0.9123649 | 0.0498907 | -0.2160782 | -0.7304125 | 54 | BCAR3;SMAD3;BMPR2;PPM1A;THBS1;NCOR2;TRIM33;TJP1;ARID4B;XIAP;SLC20A1;KLF10;APC;PMEPA1;SMAD7;CDK9;RHOA;CTNNB1;ACVR1;SMAD1;FURIN;RAB31;BMP2;FNTA;LTBP2 | non-significant |
| HALLMARK_HEME_METABOLISM | 0.9815951 | 0.9815951 | 0.0475434 | -0.1813776 | -0.7354361 | 189 | SELENBP1;CA2;HEBP1;TRIM58;TMEM9B;VEZF1;BLVRB;GDE1;HAGH;ALDH6A1;DMTN;SLC22A4;TRAK2;BLVRA;PIGQ;BTRC;NUDT4;ALAD;SLC30A1;RBM5;ERMAP;MBOAT2;ADD1;PRDX2;UROD;KLF3;RNF123;FECH;RAP1GAP;EPOR;EZH1;GCLM;BNIP3L;FTCD;SNCA;TCEA1;NFE2;DCAF10;MXI1;BTG2;CAST;SLC25A38;EIF2AK1 | non-significant |
| HALLMARK_HEDGEHOG_SIGNALING | 0.7351779 | 0.7658103 | 0.0593488 | -0.2680191 | -0.8194731 | 35 | CELSR1;HEY2;GLI1;HEY1;NRCAM;RASA1;TLE3;RTN1 | non-significant |
| HALLMARK_ANGIOGENESIS | 0.6023857 | 0.6547670 | 0.0692836 | -0.2965863 | -0.9097218 | 36 | SERPINA5;POSTN;FGFR1;JAG1;PTK2;PDGFA;MSX1;PF4;JAG2;KCNJ8 | non-significant |
| HALLMARK_DNA_REPAIR | 0.6247465 | 0.6646239 | 0.0684715 | -0.2344357 | -0.9244317 | 145 | NME3;BRF2;CCNO;NME4;VPS28;MPC2;VPS37D;DCTN4;ADCY6;POLD4;TAF9;NT5C;IMPDH2;DUT;TSG101;GPX4;RRM2B;CANT1;MPG;TK2;COX17;SURF1;GMPR2;RAE1;EIF1B;TARBP2;RPA3;SRSF6;CETN2;GTF2H5;NUDT9;GTF2F1;AAAS;POLR2J;ARL6IP1;POLR2G;POLE4 | non-significant |
| HALLMARK_PROTEIN_SECRETION | 0.4746450 | 0.5273834 | 0.0826646 | -0.2643380 | -0.9792939 | 94 | KRT18;TOM1L1;ATP6V1B1;SCAMP1;ICA1;AP2B1;ARFGEF1;SSPN;COG2;TSG101;RAB22A;ARFIP1;DST;TPD52;VPS4B;STX16;ATP6V1H;SOD1 | non-significant |
| HALLMARK_PANCREAS_BETA_CELLS | 0.4040000 | 0.4590909 | 0.0908241 | -0.3248738 | -1.0263443 | 40 | ABCC8;SYT13;SRP14;CHGA;SPCS1;PCSK1;SRP9;STXBP1;SST | non-significant |
| HALLMARK_FATTY_ACID_METABOLISM | 0.1115702 | 0.1573351 | 0.1918922 | -0.3006897 | -1.1924717 | 152 | BMPR1B;SLC22A5;REEP6;CA2;ECI1;UGDH;MAOA;ENO2;LTC4S;ELOVL5;HPGD;AOC3;HMGCL;DHCR24;CD36;HSD17B4;CRYZ;PCBD1;NTHL1;PDHB;ACOT2;ACADS;BLVRA;ALDH3A2;FASN;CIDEA;ECI2;ALAD;EPHX1;ALDOA;GLUL;RETSAT;INMT;ADIPOR2;CPT1A;HSD17B7;ETFDH;UROD;SUCLG2;ENO3;SERINC1;SUCLA2;RAP1GDS1;PTPRG;AUH;HSDL2;HAO2;ECHS1;CA4 | non-significant |
| HALLMARK_UV_RESPONSE_DN | 0.1113320 | 0.1573351 | 0.1882041 | -0.3089245 | -1.2125119 | 138 | IGF1R;IRS1;IGFBP5;SRI;APBB2;GJA1;SLC22A18;BHLHE40;INPP4B;DDAH1;AMPH;ICA1;MAGI2;CDKN1B;CDON;MGMT;PRKCE;CAP2;SMAD3;MMP16;AGGF1;PDGFRB;ITGB3;SYNJ2;CAV1;RUNX1;COL1A1;MIOS;CDC42BPA;PTEN;COL1A2 | non-significant |
| HALLMARK_NOTCH_SIGNALING | 0.2027290 | 0.2599090 | 0.1342735 | -0.4012749 | -1.2202138 | 32 | CCND1;SKP1;HEYL;ARRB1;KAT2A;JAG1;PSEN2 | non-significant |
| HALLMARK_ANDROGEN_RESPONSE | 0.1250000 | 0.1689189 | 0.1797823 | -0.3304711 | -1.2230201 | 96 | CCND1;SPDEF;BMPR1B;STK39;SORD;KRT19;ABHD2;GPD1L;ELOVL5;INPP4B;HPGD;DHCR24;APPBP2;KRT8;ACSL3;NKX3-1;AKAP12 | non-significant |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.0587045 | 0.0978408 | 0.2663507 | -0.3101699 | -1.2547543 | 184 | ACADSB;COX6C;MRPS30;ECI1;NDUFC2;NDUFA7;PDK4;CYB5A;MAOB;ALDH6A1;GLUD1;UQCRQ;NDUFA2;COX7C;TIMM13;PDHB;RHOT2;GPX4;PRDX3;CYC1;ETFB;COX17;PDHX;RETSAT;NDUFS8;SURF1;ATP6V1H;ATP1B1;UQCRC2;UQCR11;NDUFS4;CPT1A;NDUFA5;ETFDH;NDUFC1;HSPA9;ATP6V1G1;ATP6V1C1;NDUFA4;NDUFB4;SLC25A20;ACAT1;SLC25A4;SUCLA2;UQCRB;NDUFB1;NDUFAB1;COX11;COX6A1;ECHS1;ATP6V0C;NDUFS7;MRPL35;BCKDHA;RHOT1;TIMM17A;BDH2;COX8A;MRPL34;ATP6AP1;GRPEL1;ATP6V0B | non-significant |
| HALLMARK_BILE_ACID_METABOLISM | 0.0705645 | 0.1102571 | 0.2413400 | -0.3450906 | -1.3175339 | 112 | AR;ABCA3;SERPINA6;SLC27A2;NUDT12;FDXR;EPHX2;SULT2B1;BCAR3;SLC22A18;PFKM;PEX11A;ISOC1;DHCR24;PEX11G;HSD17B4;CROT;LIPE;PEX12;DIO1;SLC27A5;EFHC1;PEX19;NEDD4;GNMT;RETSAT;GNPAT;SCP2;ABCA9;SOD1;HSD3B1 | non-significant |
| HALLMARK_MYOGENESIS | 0.0227193 | 0.0405702 | 0.3524879 | -0.3314385 | -1.3470726 | 196 | TNNT1;STC2;SPDEF;PPP1R3C;AGL;CACNA1H;CACNG1;MYH11;PVALB;OCEL1;ADCY9;CLU;PGAM2;NQO1;HSPB8;CAMK2B;BHLHE40;ERBB3;PFKM;CD36;BAG1;SGCD;SSPN;ITGB5;FKBP1B;COX7A1;SH2B1;LAMA2;REEP1;TNNT3;CHRNG;SGCA;TNNC2;PSEN2;SPARC;FABP3;TSC2;COL1A1;RB1;VIPR1;MYBPH;CKMT2;EIF4A2;MYL6B;ITGA7;PPFIA4;HDAC5;AGRN;KCNH2;ENO3;COL6A3;SH3BGR;BDKRB2;SGCG;CFD;RIT1;MYOM2 | significant |
| HALLMARK_PEROXISOME | 0.0543260 | 0.0936654 | 0.2765006 | -0.3598859 | -1.3559638 | 104 | ABCC8;SEMA3C;SERPINA6;SLC27A2;CRABP2;EPHX2;SULT2B1;ELOVL5;ABCC5;ALB;PEX11A;ISOC1;HMGCL;DHCR24;HSD17B4;PEX2;CDK7;DIO1;ECI2;HSD11B2;RETSAT;FIS1;GNPAT;VPS4B;SCP2;CLN8;SOD1;PEX11B;HRAS | non-significant |
| HALLMARK_ADIPOGENESIS | 0.0064588 | 0.0169967 | 0.4070179 | -0.3440095 | -1.3979662 | 192 | QDPR;CYP4B1;REEP6;EPHX2;REEP5;CMBL;SNCG;LTC4S;HSPB8;SPARCL1;SULT1A1;DGAT1;FAH;CD36;ADCY6;PTGER3;UQCRQ;DBT;SSPN;LIPE;LPCAT3;ACADS;OMD;CD151;GPX4;PRDX3;CIDEA;RAB34;FABP4;RMDN3;PDCD4;ALDOA;TOB1;CYC1;COQ5;ETFB;MTCH2;RETSAT;GPHN;PHLDB1;LEP;MRAP;GBE1;SCP2;CCNG2;SOD1;MAP4K3;ADIPOR2;SLC27A1;RNF11;UQCR11;ADIPOQ;NDUFA5;ITGA7;LIFR | significant |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 0.0000000 | 0.0000000 | 0.9101197 | -0.5617047 | -2.2826236 | 192 | TFF1;AGR2;SCUBE2;CA12;TFF3;NPY1R;DNAJC12;CCND1;PDZK1;MAPT;ANXA9;SERPINA3;SERPINA5;PGR;COX6C;ABCA3;DHRS2;CACNA2D2;SLC22A5;TSPAN13;TPSAB1;MYB;SLC27A2;RET;BCL2;PRSS23;CHST8;IL6ST;NRIP1;CA2;ACOX2;TPBG;SCNN1A;SORD;KRT19;CELSR2;GPER1;CXCL14;SULT2B1;TFPI2;CPE;FLNB;RABEP1;CHPT1;UGDH;AMFR;ABHD2;XBP1;RBBP8;FGFR3;ELOVL5;HSPB8;ASCL1;IGFBP4;AREG;PLXNB1;ARL3;DLG5;SLC24A3;SIAH2;BAG1;BLVRB;MYOF;PLAC1;FKBP4;PTGER3;OLFM1;TJP3;EMP2;EGR3;PKP3;WFS1;DYNLT3;DCXR;PRLR;ALDH3A2;MOCS2;OVOL2;CISH;CYP4F11 | significant |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 0.0000000 | 0.0000000 | 1.3267161 | -0.6883031 | -2.7932786 | 190 | TFF1;GFRA1;CA12;TFF3;NPY1R;SLC39A6;CCND1;PDZK1;THSD4;MAPT;ANXA9;SLC7A2;SYBU;STC2;ELOVL2;MLPH;PGR;AR;MSMB;ABCA3;DHRS2;SLC22A5;SLC19A2;IGF1R;ABAT;MYB;KRT18;MAST4;SLC27A2;RET;KCNK15;BCL2;PRSS23;GREB1;IL6ST;NRIP1;UGCG;MED13L;ADCY1;RAB17;CELSR1;TPBG;SCNN1A;KRT19;CELSR2;SLC1A1;SULT2B1;ADCY9;FLNB;CHPT1;AMFR;ABHD2;XBP1;RBBP8;TTC39A;ELOVL5;HSPB8;GJA1;SEC14L2;IGFBP4;BHLHE40;AREG;SNX24;ARL3;INHBB;PEX11A;SLC24A3;MUC1;RHOBTB3;SIAH2;MPPED2;BAG1;BLVRB;MYOF;RHOD;LRIG1;FKBP4;ASB13;OLFM1;TJP3;MREG;PMAIP1;EGR3;WFS1;DYNLT3;KRT8 | significant |
| | | 0% | |==== | 5% | |======= | 11% | |=========== | 16% | |=============== | 21% | |================== | 26% | |====================== | 32% | |========================== | 37% | |============================= | 42% | |================================= | 47% | |===================================== | 53% | |========================================= | 58% | |============================================ | 63% | |================================================ | 68% | |==================================================== | 74% | |======================================================= | 79% | |=========================================================== | 84% | |=============================================================== | 89% | |================================================================== | 95% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 0.0000000 | 0.0000000 | 1.5631820 | 0.7297628 | 3.1224395 | 194 | IDO1;CXCL9;CD38;CXCL10;CCL7;CCL5;TAP1;IRF1;SLAMF7;STAT1;IRF4;BATF2;ITGB7;GBP4;CCL2;PSMB9;IL2RB;SOD2;SAMD9L;RTP4;CXCL11;ZBP1;GZMA;SOCS1;BANK1;HLA-DQA1;OASL;ISG20;XCL1;CD74;GPR18;APOL6;IL15;ICAM1;PFKP;PDE4B;PIM1;CD274;CASP1;IFI30;HLA-DMA;IFI44L;HLA-DRB1;IFIH1;PLA2G4A;P2RY14;USP18;PSMB8;MYD88;PELI1;IFI44;IL10RA;PTPN6;VCAM1;PNP;PARP12;RIPK2;C1S;LCP2;PSMB2;LAP3;IRF8;HLA-A;EPSTI1;SECTM1;IFNAR2;IL18BP;NMI;PTPN2;UBE2L6;CD40;B2M;CD69;HLA-G;CMKLR1;FAS;CASP4;IL15RA;LY6E;TAPBP;NUP93;TRIM26;NLRC5;KLRK1;IFIT3;JAK2;FPR1;STAT3;MX1;HLA-B;XAF1;C1R;LYSMD2;SOCS3;RSAD2;ADAR;UPP1;MTHFD2;PARP14;TNFAIP3;IFIT2;PSMB10;MX2;OAS2;VAMP5;STAT4;IL6;IL7;PLSCR1;SLC25A28;CIITA;SERPING1;NOD1;NFKB1 | significant |
| HALLMARK_ALLOGRAFT_REJECTION | 0.0000000 | 0.0000000 | 1.4885397 | 0.7095159 | 3.0314088 | 195 | CCL13;CXCL13;CXCL9;GZMB;CCL19;CCL7;CDKN2A;CCL5;LCK;TAP1;IL27RA;CD2;STAT1;CD79A;IRF4;IFNG;LTB;CD3D;CCL2;HLA-DOB;IL2RB;SIT1;HLA-E;LYN;MMP9;ZAP70;GZMA;SOCS1;HLA-DQA1;CCR2;CCR5;CCL4;CD96;CD247;FASLG;CD3G;CD74;PRKCB;CXCR3;CTSS;IL15;CFP;ICAM1;LY75;IL2RG;CD40LG;NCF4;C2;PRF1;HLA-DMA;HCLS1;NCK1;TLR1;PTPN6;IL2RA;MAP4K1;ITK;TNF;RIPK2;KLRD1;SRGN;LCP2;IRF8;HLA-A;TRAT1;EIF5A;IFNAR2;CD47;CD7;HLA-DRA;CSK;TLR2;CD40;B2M;IL1B;CD8A;TLR6;FGR;HLA-G;CD8B;FAS;CCR1;TAPBP;IL18;CD28;JAK2;TAP2;IL18RAP;TIMP1;CRTAM;ITGAL;CCND2;IL13;PSMB10;FCGR2B;CAPG;SPI1;RPS19;STAT4;PTPRC;IL6;IFNGR1;IL7;GBP2 | significant |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 0.0000000 | 0.0000000 | 1.0476265 | 0.7152560 | 2.7667996 | 94 | LAMP3;CXCL10;TAP1;IRF1;BATF2;GBP4;SELL;PSMB9;SAMD9L;RTP4;CXCL11;OASL;ISG20;CD74;IL15;NCOA7;HLA-C;CASP1;IFI30;IFI44L;IFIH1;USP18;PSMB8;IFI44;PARP12;RIPK2;C1S;LAP3;EPSTI1;CD47;NMI;UBE2L6;B2M;OAS1;LY6E;TRIM26;IFIT3;MX1;RSAD2;ADAR;PARP14;IFIT2;PARP9;IL7;GBP2;PLSCR1;SLC25A28 | significant |
| HALLMARK_E2F_TARGETS | 0.0000000 | 0.0000000 | 1.1512205 | 0.6217707 | 2.6565172 | 195 | CDKN2A;CCNE1;ANP32E;MELK;KIF2C;NCAPD2;CDC20;CDCA3;LBR;MCM2;MYBL2;CDCA8;CKS1B;CHEK1;MCM4;DEK;CTPS1;GINS4;HMGA1;RFC2;RAD51AP1;MCM5;TUBB;CDC25A;NUP205;MCM3;CENPE;ORC6;PLK1;NASP;USP1;KIF4A;CHEK2;EZH2;BUB1B;UBE2T;TACC3;ZW10;MCM6;CDC25B;CDK1;STMN1;SSRP1;KPNA2;AURKB;MMS22L;DLGAP5;NUP153;PRPS1;LYAR;RPA2;TOP2A;DSCC1;TRIP13;CCNB2;PTTG1;SNRPB;RANBP1;MCM7;PCNA;ATAD2;LMNB1;MTHFD2;CDKN2C;PRIM2;GINS3;BIRC5;MAD2L1;POLD1;DONSON;EED;AURKA;SMC6;DEPDC1;MYC;SPAG5;EXOSC8;DIAPH3;ILF3;PRKDC;POLA2;UNG;SHMT1;PRDX4;MSH2;SMC3;ING3;RPA1;MKI67;PLK4;LIG1;RNASEH2A;SRSF2;TCF19;GINS1;KIF18B;SMC4;SLBP;PSMC3IP;RFC3;DNMT1;STAG1;ASF1A;NOP56;NUDT21;RAD1;HMGB3;CIT;PSIP1;UBE2S;XRCC6;POLD2;POLD3;SYNCRIP;RAN | significant |
| HALLMARK_G2M_CHECKPOINT | 0.0000000 | 0.0000000 | 0.9436322 | 0.5588274 | 2.3771761 | 188 | KIF2C;CDC20;LBR;MCM2;MYBL2;NDC80;CCNA2;CKS1B;CENPA;ODC1;CHEK1;TTK;UCK2;RAD54L;BUB1;EXO1;CENPF;TPX2;HMGA1;E2F3;MCM5;EFNA5;CDC25A;MCM3;CENPE;ORC6;CDC45;CDC7;PLK1;NASP;KIF4A;EZH2;KIF11;SMARCC1;PBK;E2F2;TACC3;UBE2C;SLC7A5;MCM6;CDC25B;AMD1;CDK1;STMN1;KPNA2;KIF15;AURKB;NEK2;INCENP;CUL1;WRN;E2F1;RPA2;TOP2A;CCNB2;PTTG1;HIRA;TFDP1;LMNB1;TROAP;FANCC;MTF2;CDKN2C;PRIM2;BIRC5;MAD2L1;TRAIP;POLQ;PAFAH1B1;AURKA;RASAL2;SNRPD1;SAP30;ATF5;KATNA1;MYC;STIL;DR1;ILF3;POLA2;KIF23;NOTCH2;E2F4;DKC1;DMD;CHAF1A;MKI67;PLK4;RBL1;SRSF2 | significant |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.0000000 | 0.0000000 | 0.7749390 | 0.6228651 | 2.3532537 | 87 | CXCL13;CXCL9;CD38;CXCL10;CCL7;CXCL1;IRF1;STAT1;LTB;TNFRSF21;CXCL11;SOCS1;IL1R2;EBI3;CD14;PIM1;IL2RG;MYD88;IL2RA;TNF;PTPN2;IL17RA;TLR2;IL1B;BAK1;FAS;CSF2RA;CCR1;IL15RA;A2M;STAT3;TNFRSF1B;SOCS3;CD44;IL3RA;ACVRL1;IL6;IFNGR1;IL7;LTBR | significant |
| HALLMARK_INFLAMMATORY_RESPONSE | 0.0000000 | 0.0000000 | 0.9325952 | 0.5477553 | 2.3383354 | 197 | MARCO;LAMP3;CXCL9;CXCL10;CCL7;CCR7;CCL5;CCL17;LCK;IRF1;ITGB8;CX3CL1;CCL2;SELL;IL2RB;RASGRP1;CXCR6;LYN;GPR183;RTP4;CXCL11;ADORA2B;IL7R;EBI3;CD82;CHST2;IL15;ICAM1;ICAM4;CD14;SLAMF1;PDE4B;CD48;SPHK1;TLR1;ADM;IL10RA;CYBB;KIF1B;RIPK2;LCP2;TNFRSF9;NMI;TLR2;CD40;IL1B;RNF144B;GPR132;CD69;GNA15;CMKLR1;PTAFR;AQP9;IL15RA;LY6E;TAPBP;IL18;KCNA3;RHOG;IRAK2;FPR1;RAF1;IL18RAP;TIMP1;TNFRSF1B;PROK2;SELE;SGMS2;PLAUR | significant |
| HALLMARK_COMPLEMENT | 0.0000009 | 0.0000042 | 0.6594444 | 0.4350545 | 1.8607071 | 198 | LTF;GZMB;CCL5;CXCL1;LCK;CP;IRF1;PSMB9;CTSV;RASGRP1;GZMK;LYN;GZMA;FCN1;PLA2G7;C1QA;PLEK;CTSS;SPOCK2;PIM1;CD40LG;CR2;CASP1;C2;C1QC;PFN1;CEBPB;PLA2G4A;CTSC;APOBEC3G;C1S;LCP2;LAP3;APOBEC3F;C3;S100A9;CASP4;GNGT2;XPNPEP1;RHOG;JAK2;CASP5;RAF1;PRSS3;KLK1;PREP;CTSL;C1R;TIMP1;L3MBTL4;PLAUR;TNFAIP3;LGMN;EHD1;CPQ;ITGAM;PHEX;PIK3CG;IL6;PLSCR1 | significant |
| HALLMARK_MYC_TARGETS_V1 | 0.0000037 | 0.0000156 | 0.6272567 | 0.4328957 | 1.8532088 | 193 | TYMS;CDC20;MCM2;IFRD1;CCNA2;ODC1;MCM4;DEK;SRPK1;CTPS1;MCM5;ILF2;MRPL9;CDC45;CSTF2;USP1;PSMB2;RFC4;SMARCC1;PSMC4;LSM2;C1QBP;SRM;MCM6;FBL;KPNA2;CUL1;SNRPA1;STARD7;RANBP1;MCM7;PCNA;TFDP1;CAD;LSM7;MAD2L1;PWP1;PPM1G;PHB2;DDX21;SNRPD1;POLE3;MYC;RPS10;CCT4;SERBP1;PSMD7;PRDX4;EIF4A1;VDAC3;YWHAQ;RPS6;HDGF;SRSF2;HSP90AB1;HPRT1;UBA2;HDAC2;DDX18;SF3B3;PSMA4;RUVBL2;PSMD8;NOP56;U2AF1;XPOT;ABCE1;XRCC6;POLD2;CCT3;SYNCRIP;RAN;UBE2L3;NOP16;TUFM;EIF4H;CDK4;EXOSC7;EIF3B;PRPF31;RRP9;EIF4G2;PCBP1;RNPS1;HSPD1;TRA2B;PSMD14 | significant |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.0000073 | 0.0000281 | 0.6105269 | 0.4213221 | 1.7985994 | 197 | CXCL10;CCL5;CXCL1;PTX3;TAP1;IRF1;CCL2;SOD2;GPR183;CXCL11;LAMB3;IL7R;CCL4;BIRC3;NFIL3;BCL2A1;PLEK;BTG3;ICAM1;DUSP2;PDE4B;CFLAR;SPHK1;CEBPB;MAP2K3;NFKBIE;IFIH1;TRAF1;VEGFA;RELB;CD83;TNF;RIPK2;STAT5A;TNFRSF9;TLR2;CXCL2;IL1B;FUT4;CD69;RCAN1;PNRC1;EGR2;TANK;MCL1;B4GALT5;IL15RA;IL18;TUBB2A;SERPINB8;EFNA1;IL23A;TNFAIP8;SOCS3;PLAUR;CD44;TNFAIP3;EHD1;IFIT2;CEBPD;LITAF;IL6;EDN1;FJX1;B4GALT1;MYC;YRDC;DRAM1;NFKB1;TNFAIP2;SLC2A6;BIRC2 | significant |
| HALLMARK_IL2_STAT5_SIGNALING | 0.0000176 | 0.0000628 | 0.5756103 | 0.4131564 | 1.7677743 | 194 | CXCL10;S100A1;CCNE1;GLIPR2;CD79B;IRF4;LTB;GBP4;ICOS;TNFRSF21;SELL;IL2RB;SOCS1;IL1R2;NOP2;NFIL3;ODC1;BATF3;TNFRSF8;UCK2;PIM1;CD48;CTLA4;TRAF1;IL10RA;PNP;IL2RA;TNFRSF4;NDRG1;RRAGD;CD83;IRF6;IRF8;TNFRSF9;EOMES;GALM;SLC1A5;DCPS;ITGA6;TTC39B;COCH;TNFRSF1B;TGM2;CST7;CCND2;IL13;CD44;PDCD2L;CDC42SE2;ETV4;RABGAP1L;CAPG;PUS1;IL3RA;ADAM19;LRRC8C;IFNGR1;FLT3LG;PLSCR1;MYC;PRNP | significant |
| HALLMARK_MTORC1_SIGNALING | 0.0000334 | 0.0001114 | 0.5573322 | 0.4067936 | 1.7405495 | 194 | PHGDH;PSAT1;DAPP1;CORO1A;FADS2;MCM2;IFRD1;NFIL3;PDK1;DDIT4;MCM4;CFP;BUB1;IFI30;ASNS;MAP2K3;STARD4;GLRX;CDC25A;SLA;NUP205;CTSC;TES;PNP;CXCR4;SSR1;ENO1;PLK1;RPN1;PSMC4;SLC7A5;NFKBIB;SLC1A5;UCHL5;GAPDH;PGM1;ACTR3;PITPNB;M6PR;DHCR7;TPI1;VLDLR;EEF1E1;MTHFD2;PSMG1;ABCF2;LGMN;ARPC5L;PSMC2;HMBS;AURKA;SRD5A1;PNO1;TUBA4A;POLR3G;UNG;CALR;GMPS;HMGCS1;SDF2L1;NFYC;YKT6;HSP90B1;CCT6A;SKAP2;MLLT11;FGL2;RPA1;SHMT2;FADS1;HPRT1;GOT1;PPA1;PSME3;EGLN3;ITGB2;ACLY;GSK3B;PSMA4;SLC2A1 | significant |
| HALLMARK_MYC_TARGETS_V2 | 0.0027751 | 0.0069378 | 0.4317077 | 0.4858569 | 1.7169043 | 57 | NOP2;MCM4;DUSP2;MCM5;BYSL;PLK1;SRM;RCL1;MYBBP1A;MPHOSPH10;PUS1;PPRC1;MYC;GRWD1;WDR74;UNG;TFB2M;MRTO4;PLK4;PPAN;DDX18;EXOSC5;NOP56;SUPV3L1;MAP3K6;NDUFAF4;UTP20;NOP16;CDK4;PES1;RRP9;HSPD1;LAS1L;NOC4L;NOLC1;TCOF1 | significant |
| HALLMARK_MITOTIC_SPINDLE | 0.0002783 | 0.0008185 | 0.4984931 | 0.3815961 | 1.6290117 | 197 | KIF2C;NDC80;TTK;BUB1;ANLN;GEMIN4;FSCN1;CENPF;TPX2;CEP72;MID1;NCK1;CENPE;KIF1B;PLK1;NCK2;KIF4A;KIF11;PIF1;ARHGEF2;CDK1;KIF15;CEP192;NEK2;INCENP;DLGAP5;EPB41L2;TOP2A;SUN2;ARHGAP27;CCNB2;CDC42EP1;ECT2;ACTN4;NET1;DOCK2;BIN1;LMNB1;CEP57;RALBP1;BIRC5;ARHGEF3;PAFAH1B1;AURKA;KNTC1;RASAL2;TUBD1;KATNA1;TUBA4A;CDC42EP4;GSN;SORBS2;KIF23;NOTCH2;CENPJ;SMC3;HOOK3;CSNK1D;KIF20B;CKAP5;RHOF;CNTROB;ABI1;SMC4;PLEKHG2;SAC3D1;FLNA;PRC1;DLG1;RASA2 | significant |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.0059718 | 0.0135723 | 0.4070179 | 0.3874692 | 1.5262915 | 106 | PSAT1;CCL2;CKS1B;DDIT4;CEBPG;GEMIN4;CEBPB;ASNS;VEGFA;PDIA5;SSR1;SLC7A5;NABP1;HYOU1;TUBB2A;SPCS3;KDELR3;MTHFD2;CXXC1;HERPUD1;SRPRB;EIF4G1;TATDN2;NFYA;PDIA6;CALR;ATF4;EIF4A1;HSP90B1;POP4;DKC1;PREB;ALDH18A1;EXOSC5;FUS;EXOSC10;NOP56;DNAJB9 | significant |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 0.0187059 | 0.0359729 | 0.3524879 | 0.3712101 | 1.4642968 | 104 | LCK;DAPP1;FASLG;PDK1;PRKCB;IL2RG;PFN1;MAP2K3;NCK1;SLA;MYD88;CXCR4;CDK1;MAPK1;NFKBIB;MAP2K6;E2F1;ACTR3;RAF1;CSNK2B;NGF;ARF1;NOD1;MKNK1;RPS6KA3;MAP3K7;SFN;CALR;HSP90B1;GNGT1 | significant |
| HALLMARK_KRAS_SIGNALING_UP | 0.0032145 | 0.0076537 | 0.4317077 | 0.3380277 | 1.4393875 | 191 | CXCL10;KCNN4;ADAMDEC1;HSD11B1;MPZL2;LCP1;GPRC5B;MMP9;SLPI;SOX9;IL7R;BIRC3;TMEM176B;TMEM100;CTSS;TMEM158;IL2RG;CD37;MALL;GLRX;CLEC4A;IKZF1;PSMB8;LAPTM5;TMEM176A;TRAF1;MYCN;IL10RA;ST6GAL1;CXCR4;MAP4K1;IRF8;GALNT3;IL1B;GYPC;TLR8;BTBD3;CMKLR1;CSF2RA;SATB1;ADAM8;PCSK1N;TNFRSF1B;DOCK2;CCND2;PLAUR;PCP4;ADAM17;TNFAIP3;ETV4;RABGAP1L | significant |
| HALLMARK_KRAS_SIGNALING_DN | 0.0064608 | 0.0140453 | 0.4070179 | 0.3275109 | 1.3946047 | 191 | KRT5;KLK8;KRT15;CALML5;SLC6A14;SOX10;TCL1A;KLK7;TFCP2L1;IFNG;TCF7L1;PDCD1;TGM1;KRT13;LGALS7;CHST2;CD40LG;IFI44L;GPR19;STAG3 | significant |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 0.0681265 | 0.1174595 | 0.2712886 | 0.3942551 | 1.3134104 | 42 | WNT6;DKK1;SKP2;TCF7;CUL1;WNT5B;NOTCH1;CCND2;ADAM17;PPARD;NCSTN;MYC | non-significant |
| HALLMARK_UV_RESPONSE_UP | 0.0265053 | 0.0473309 | 0.3524879 | 0.3171729 | 1.3088239 | 154 | TAP1;IRF1;CCNE1;GAL;CTSV;HLA-F;SOD2;RASGRP1;LYN;CEBPG;CCK;BTG3;ICAM1;ASNS;FEN1;BID;KLHDC3;RFC4;RPN1;E2F5;CHRNA5;COL2A1;GGH;CXCL2;AMD1;BAK1;NPTX2;ALAS1;ARRB2 | significant |
| HALLMARK_P53_PATHWAY | 0.0211672 | 0.0391985 | 0.3524879 | 0.3055945 | 1.3012806 | 191 | KLK8;KRT17;CDKN2A;LDHB;TAP1;TM4SF1;SOCS1;SERPINB5;TCN2;DDIT4;CD82;STEAP3;CASP1;IFI30;SPHK1;NDRG1;APP;ST14;BAK1;SEC61A1;IRAK1;DEF6;FAS;TPD52L1;SLC3A2;PERP;HSPA4L;ADA;S100A10;S100A4;RHBDF2;FBXW7;PCNA;UPP1;NOTCH1;CCND2 | significant |
| HALLMARK_APICAL_JUNCTION | 0.1000000 | 0.1470588 | 0.2343926 | 0.2825600 | 1.2052497 | 190 | CDH3;ACTG2;CX3CL1;MPZL2;NRTN;ICAM2;CLDN4;MMP9;LAMB3;ICAM1;ICAM4;CD274;MDK;PFN1;FSCN1;ITGA9;DSC3;MSN;TRAF1;VCAM1;CALB2;MPZL1;RAC2;NFASC;ADAM15;SYK;RSU1;DHX16;LAMC2;EPB41L2;ACTN4;SPEG;ACTB;COL9A1;PTPRC;ITGB4;SIRPA;TIAL1;B4GALT1;MVD | non-significant |
| HALLMARK_APICAL_SURFACE | 0.1975309 | 0.2469136 | 0.1552420 | 0.3550673 | 1.1866576 | 43 | CX3CL1;IL2RB;LYN;MAL;IL2RG;ATP6V0A4;GHRL;RHCG;EFNA5;APP;AKAP7 | non-significant |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 0.1876543 | 0.2405825 | 0.1596467 | 0.3142112 | 1.1588065 | 72 | CBS;GLDC;FADS2;NFIL3;S100A11;STARD4;FABP5;FBXO6;CXCL16;PNRC1;DHCR7;PLAUR;LGMN;ACAT2;PLSCR1;ATF5;MVD;ANXA5;HMGCS1;SREBF2;PDK3;FDPS | non-significant |
| HALLMARK_APOPTOSIS | 0.1556122 | 0.2047530 | 0.1797823 | 0.2787664 | 1.1576283 | 159 | CD38;TAP1;IRF1;CD2;SOD2;ISG20;FASLG;BIRC3;BTG3;CD14;CFLAR;CASP1;PRF1;BID;TNF;APP;IL1B;CDC25B;CD69;GNA15;NEFH;FAS;MCL1;CASP4;SATB1;CASP6;IL18;TOP2A;DFFA;TIMP1;LMNA;CCND2;CD44;BAX;PAK1;PLCB2;IL6;IFNGR1;CCNA1;DAP;GSN;TSPO;DAP3 | non-significant |
| HALLMARK_HYPOXIA | 0.2060440 | 0.2512731 | 0.1608014 | 0.2586199 | 1.1012534 | 191 | CP;CSRP2;ADORA2B;ISG20;CHST3;NFIL3;PDK1;DDIT4;PLAC8;CHST2;PFKP;PIM1;GLRX;ADM;TES;VEGFA;NDRG1;CXCR4;RRAGD;ENO1;SCARB1;PKP1;GCNT2;PNRC1;CASP6;XPNPEP1;LALBA;TMEM45A;GAPDH;PGM1;EFNA1;S100A4;TGM2;KDELR3;TPI1;VLDLR;NAGK;PLAUR;TNFAIP3;UGP2 | non-significant |
| HALLMARK_GLYCOLYSIS | 0.2136752 | 0.2543753 | 0.1608014 | 0.2571276 | 1.0976627 | 197 | DSC2;SOX9;ADORA2B;ISG20;CHST6;CENPA;DDIT4;CHST2;PFKP;GLRX;VEGFA;GNE;CXCR4;CLDN3;RRAGD;PYGB;ENO1;NASP;KIF20A;PSMC4;PLOD1;CDK1;STMN1;ELF3;CASP6;PRPS1;SLC25A13;GPR87;KDELR3;MDH2;TPI1;SPAG4;VLDLR;PKP2;COPB2;CD44;UGP2;BPNT1;CHST12;AURKA;CHST4;SAP30;DEPDC1;AKR1A1;GALK2;ME2;B4GALT1 | non-significant |
| HALLMARK_SPERMATOGENESIS | 0.4043127 | 0.4594462 | 0.1088201 | 0.2533506 | 1.0136769 | 132 | IL12RB2;ART3;KIF2C;RPL39L;TTK;BUB1;RFC4;EZH2;TLE4;GFI1;LPIN1;CDK1;NEFH;OAZ3;NEK2;PCSK1N;HSPA4L;POMC;CCNB2;PSMG1;AURKA;CCNA1;ADAD1;SLC2A5;VDAC3;BRAF;CFTR;NAA11;MLLT10;MTOR;NF2;NCAPH;TOPBP1;LDHC;TSN;CLPB;DBF4 | non-significant |
| HALLMARK_DNA_REPAIR | 0.5646438 | 0.6195281 | 0.0875697 | 0.2335727 | 0.9499754 | 145 | TYMS;PDE4B;FEN1;RFC2;HCLS1;PNP;RFC4;SF3A3;SUPT5H;VPS37B;SEC61A1;SSRP1;POLR1C;CLP1;ADA;POLR2D;RPA2;TAF1C;RFC5;PCNA;DGCR8;GTF3C5;POLD1;ERCC3;NELFB;POLR2F;RAD51;ITPA;UPF3B;GTF2B;POLA2;NELFE;RNMT;POLR2C;LIG1;HPRT1;NT5C3A;TAF13;RFC3;SAC3D1;PDE6G;NUDT21;RAD52;POLR2J;POLR2I | non-significant |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 0.7261614 | 0.7409810 | 0.0702813 | 0.2546959 | 0.8722800 | 47 | SOD2;MGST1;PFKP;GLRX;LSP1;PRNP;STK25;PRDX4;NDUFS2;FES;MSRA;MPO | non-significant |
| HALLMARK_HEME_METABOLISM | 0.9052133 | 0.9052133 | 0.0394367 | -0.2027954 | -0.8070288 | 189 | HBB;TRIM58;BLVRB;HBD;HAGH;VEZF1;BLVRA;NUDT4;MBOAT2;TRAK2;HEBP1;RAP1GAP;TMEM9B;TSPAN5;ABCB6;ALDH6A1;PIGQ;PGLS;ARL2BP;ABCG2;TAL1;SELENBP1;SLC22A4;TNS1;KLF3;GDE1;DAAM1;FECH;BCAM;HBQ1;GYPA;SYNJ1;BNIP3L | non-significant |
| HALLMARK_HEDGEHOG_SIGNALING | 0.6459732 | 0.6728887 | 0.0577309 | -0.2924631 | -0.8877398 | 35 | GLI1;CELSR1;HEY1;CRMP1;THY1;TLE3;RASA1 | non-significant |
| HALLMARK_NOTCH_SIGNALING | 0.5699659 | 0.6195281 | 0.0645031 | -0.3158700 | -0.9336782 | 32 | CCND1;SKP1;WNT5A;LFNG;ARRB1;HEYL;DLL1 | non-significant |
| HALLMARK_PROTEIN_SECRETION | 0.5904605 | 0.6281495 | 0.0610364 | -0.2572124 | -0.9366284 | 94 | KRT18;TOM1L1;TSPAN8;SCAMP1;SOD1;GALC;SCRN1;RAB22A;SSPN;ARFIP1;STX16;TSG101;ICA1;CAV2;AP2B1;TPD52;SGMS1;CLN5;SH3GL2 | non-significant |
| HALLMARK_PEROXISOME | 0.4029126 | 0.4594462 | 0.0793435 | -0.2795655 | -1.0283971 | 104 | ABCC8;SULT2B1;PEX11A;SEMA3C;CRAT;SLC27A2;DHCR24;ELOVL5;ISOC1;ABCC5;SOD1;LONP2;SERPINA6;CRABP2;HRAS;ALB;ACOX1;RDH11;HMGCL;DIO1;CDK7;SLC25A4;ECI2;CLN8;TTR | non-significant |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.1323764 | 0.1838561 | 0.1521449 | -0.2982483 | -1.1791649 | 184 | COX6C;ACADSB;PDK4;CYB5A;NDUFC2;NDUFA2;ATP6V1G1;GPX4;CPT1A;MRPS30;ETFB;ATP6V1D;ATP6AP1;UQCRQ;TIMM13;HSPA9;ALDH6A1;NDUFB4;NDUFB1;NDUFA7;COX17;UQCRB;COX7C;ETFDH;PDHB;UQCR11;ECI1;COX5A;NDUFA6;ACAA2;SURF1;SLC25A4;COX6A1;RHOT2;GRPEL1;CYC1;PRDX3;COX11;GLUD1;ATP6V1C1;GOT2;MRPL34;NDUFS8;SUCLA2;SLC25A6;CASP7;NDUFS4;NDUFC1 | non-significant |
| HALLMARK_XENOBIOTIC_METABOLISM | 0.1238245 | 0.1768921 | 0.1563124 | -0.2992047 | -1.1938718 | 194 | ACOX2;ESR1;NQO1;FBP1;UGDH;BLVRB;MAOA;ABCC3;PDK4;FAH;ACSM1;CYB5A;DCXR;IGFBP4;CD36;NINJ1;ELOVL5;KYNU;RAP1GAP;MCCC2;CDO1;HES6;SERPINA6;CSAD;GSTT2;ABHD6;CYP26A1;PTGES3;CROT;ETFDH;MPP2;GNMT;FBLN1;GSS;ACOX1 | non-significant |
| HALLMARK_COAGULATION | 0.0985460 | 0.1470588 | 0.1797823 | -0.3221999 | -1.2312381 | 137 | ACOX2;PLAT;COMP;MMP11;HTRA1;TIMP3;PRSS23;FBN1;SPARC;HPN;CFD;MMP10;TFPI2;TMPRSS6;ITGA2;CTSK;CRIP2;MMP14;OLR1;F2RL2;MMP2;FGG;THBS1;F12;CTSO;GNG12;FN1 | non-significant |
| HALLMARK_BILE_ACID_METABOLISM | 0.0830671 | 0.1339792 | 0.1957890 | -0.3406667 | -1.2697958 | 112 | AR;PEX11G;NUDT12;FDXR;SULT2B1;PEX11A;SLC27A2;ABCA3;DHCR24;LIPE;SLC22A18;PEX16;ISOC1;SOD1;LONP2;SERPINA6;HSD3B1;NEDD4;ABCA5;CROT;GNMT;PFKM;ABCA9;DIO1;AKR1D1;BCAR3;PEX7;PEX19;DIO2;TTR;PEX12;HSD17B6;PECR;ATXN1;AMACR;PXMP2;ABCA6;SCP2;ABCA2;HSD17B4;APOA1;RXRA;EPHX2;NR3C2;ABCD3 | non-significant |
| HALLMARK_PANCREAS_BETA_CELLS | 0.1369637 | 0.1850861 | 0.1521449 | -0.4099242 | -1.2832300 | 40 | SYT13;ABCC8;SCGN;STXBP1;SRP9;ELP4;PCSK2;SRP14;GCG;NKX2-2 | non-significant |
| HALLMARK_ANGIOGENESIS | 0.0949153 | 0.1470588 | 0.1882041 | -0.4381199 | -1.3384691 | 36 | SERPINA5;COL3A1;POSTN;COL5A2;LUM;PDGFA;VCAN;OLR1;FGFR1;FSTL1;MSX1 | non-significant |
| HALLMARK_TGF_BETA_SIGNALING | 0.0713101 | 0.1188502 | 0.2165428 | -0.4128886 | -1.3700102 | 54 | RAB31;TGFBR1;CDKN1C;BMPR2;THBS1;PMEPA1;SLC20A1;SMAD3;BCAR3;APC;SMURF1;LTBP2;XIAP;KLF10;NCOR2;SMAD1;SERPINE1;SMAD7;TRIM33;SMAD6;SPTBN1;PPM1A;TJP1;SKIL | non-significant |
| HALLMARK_FATTY_ACID_METABOLISM | 0.0079149 | 0.0164894 | 0.3807304 | -0.3773177 | -1.4564845 | 152 | REEP6;HPGD;UGDH;SLC22A5;FASN;MAOA;CRAT;DHCR24;ACOT2;BLVRA;CD36;BMPR1B;SERINC1;LTC4S;ELOVL5;ENO2;AOC3;MGLL;CIDEA;INMT;CPT1A;ETFDH;SUCLG2;ALDOA;PDHB;ECI1;ACOX1;RDH11;HMGCL;CA4;ACADL;ACAA2;HSDL2;PTPRG;ECI2;ADIPOR2;GLUL;CRYZ;HSPH1;GSTZ1;NTHL1;RDH16;GPD2;ALDH3A2;SUCLA2 | significant |
| HALLMARK_ANDROGEN_RESPONSE | 0.0178799 | 0.0357599 | 0.3524879 | -0.4088864 | -1.4962678 | 96 | SPDEF;HPGD;CCND1;SORD;SCD;INPP4B;GPD1L;DHCR24;STK39;STEAP4;KRT19;AKAP12;KRT8;BMPR1B;ELOVL5;ABHD2;HOMER2;HERC3;ANKH;PMEPA1;ACSL3;KLK3;TPD52;APPBP2;TSC22D1;ZMIZ1;MAK;PA2G4 | significant |
| HALLMARK_ADIPOGENESIS | 0.0004326 | 0.0012015 | 0.4984931 | -0.3920536 | -1.5633620 | 192 | REEP6;CYP4B1;HSPB8;REEP5;FZD4;OMD;TOB1;CRAT;FAH;SPARCL1;LIPE;PTGER3;FABP4;CD36;QDPR;LTC4S;DGAT1;MGLL;CIDEA;SULT1A1;GPX4;ETFB;SOD1;UQCRQ;CD151;SSPN;MAP4K3;ALDOA;UQCR11;SLC27A1;ADIPOQ;ACOX1;DNAJC15;ACADL;ACAA2;STOM;ADCY6;GPHN;PDCD4;SNCG;CCNG2;GPAM;COX6A1;GRPEL1;ADIPOR2;CYC1;GHITM;PFKFB3;PHLDB1;TST;PRDX3;GADD45A;COL15A1;MRAP;GPX3;GPD2;DBT;BAZ2A;BCL6;GBE1;VEGFB;DHRS7;COX8A;LIFR;RMDN3;ARL4A;ITGA7;LEP;SCP2;LPCAT3;PPARG;ELOVL6;LAMA4 | significant |
| HALLMARK_UV_RESPONSE_DN | 0.0014339 | 0.0037734 | 0.4550599 | -0.4131834 | -1.5797795 | 138 | IGFBP5;COL11A1;IRS1;COL3A1;COL1A1;COL1A2;GJA1;IGF1R;PDGFRB;INPP4B;DUSP1;COL5A2;SLC22A18;ANXA2;MAGI2;BHLHE40;AMPH;MGLL;APBB2;MMP16;MGMT;AGGF1;CAV1;SRI;SNAI2;PRKAR2B;KCNMA1;BDNF;LPAR1;RUNX1;ICA1;SMAD3;PTPRM;DLC1;MTA1;DAB2 | significant |
| HALLMARK_MYOGENESIS | 0.0000776 | 0.0002425 | 0.5384341 | -0.4292958 | -1.7197116 | 196 | TNNT1;SPDEF;PPP1R3C;APOD;NQO1;STC2;COL3A1;COL1A1;SCD;CACNA1H;HSPB8;AEBP1;PVALB;SPARC;COX7A1;CRAT;CFD;REEP1;CACNG1;ITGB5;AGL;CAV3;ADCY9;TNNC2;BDKRB2;CD36;CAMK2B;MYOM2;IGFBP7;SGCD;BHLHE40;OCEL1;VIPR1;MYH11;COL6A3;MB;HRC;ERBB3;ATP6AP1;MYL7;SSPN;CHRNG;CDH13;FKBP1B;FST;TAGLN;PFKM;MAPK12;GABARAPL2;CASQ2;PTGIS;TPM2;PLXNB2;MYL2;ADAM12;PGAM2;CTF1;FXYD1;COL15A1;GAA;GPX3;CKMT2;FHL1;MYH8;FABP3;MYBPH | significant |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 0.0000002 | 0.0000008 | 0.6901325 | -0.4777132 | -1.9110822 | 195 | AREG;COMP;COL11A1;MATN3;SPOCK1;COL3A1;HTRA1;COL1A1;IGFBP2;FAP;POSTN;COL1A2;GJA1;COL8A2;TIMP3;PDGFRB;THBS2;SFRP4;FBN1;SPARC;FSTL3;COL12A1;EDIL3;ECM2;RHOB;ITGB5;TFPI2;COL5A2;ECM1;CDH11;INHBA;IGFBP4;LUM;LOXL1;LRRC15;SGCD;MFAP5;ITGA2;COL5A1;DCN;WNT5A;PRRX1;NTM;NID2;ENO2;COL6A3;EFEMP2;ACTA2;GPC1;GREM1;MMP14;CTHRC1;VCAN;SGCB;OXTR;THY1;MMP2;SNAI2;FZD8;THBS1;SDC4;PMEPA1;BDNF;CXCL12;SLIT3;VEGFC;TAGLN;GEM;FBLN1;LAMA3;MYL9;MXRA5;FN1;FSTL1;DPYSL3;MSX1;FERMT2;TPM2;DAB2;SLIT2 | significant |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 0.0000000 | 0.0000000 | 0.9545416 | -0.5718600 | -2.2803623 | 192 | AGR2;TFF1;CA12;TFF3;ACOX2;SCUBE2;DHRS2;PDZK1;ANXA9;AREG;NPY1R;TPSAB1;DNAJC12;CHST8;COX6C;RET;CXCL14;MAPT;SERPINA5;PGR;CACNA2D2;CCND1;UGDH;SORD;SCNN1A;CPE;SLC22A5;MYB;OLFM1;NRIP1;HSPB8;TSPAN13;CISH;BLVRB;SULT2B1;PRSS23;SERPINA3;GPER1;EGR3;TOB1;SLC27A2;ABCA3;TFPI2;AMFR;PTGER3;BCL2;DCXR;KRT19;EMP2;IGFBP4;IL6ST;WFS1;RABEP1;ASCL1;CELSR2;ELOVL5;ABHD2;TPBG;RAB31;ARL3;ST6GALNAC2;CYP4F11;PLAC1;ETFB;DLG5;CAV1;XBP1;HOMER2;SOX3;DYNLT3;TJP3;LLGL2;FGFR3;MYOF;SLC24A3;PRKAR2B;MOCS2;GALE;CXCL12;PRLR | significant |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 0.0000000 | 0.0000000 | 1.1512205 | -0.6378163 | -2.5376347 | 190 | TFF1;CA12;TFF3;MSMB;SLC7A2;DHRS2;PDZK1;ANXA9;AR;AREG;NPY1R;SLC39A6;MLPH;GFRA1;THSD4;RET;MAPT;SLC1A1;SYBU;PGR;MAST4;CCND1;SCNN1A;STC2;SLC22A5;MYB;SLC19A2;KRT18;ELOVL2;OLFM1;UGCG;ABAT;FASN;NRIP1;HSPB8;GREB1;GJA1;IGF1R;CISH;BLVRB;SULT2B1;PEX11A;PRSS23;RAB17;EGR3;TOB1;SLC27A2;REEP1;ABCA3;AMFR;MPPED2;ADCY1;BCL2;KRT19;ADCY9;IGFBP4;IL6ST;WFS1;KRT8;TSKU;RHOBTB3;TTC39A;BHLHE40;CELSR2;KCNK15;ELOVL5;P2RY2;ABHD2;TPBG;CANT1;RAB31;ARL3;DEPTOR;CELSR1;PMAIP1;XBP1;LRIG1;MED13L;SOX3;DYNLT3;TJP3;TIPARP;CBFA2T3;MYOF;SLC24A3;MREG | significant |
| | | 0% | |==== | 5% | |======= | 10% | |========== | 15% | |============== | 20% | |================== | 25% | |===================== | 30% | |======================== | 35% | |============================ | 40% | |================================ | 45% | |=================================== | 50% | |====================================== | 55% | |========================================== | 60% | |============================================== | 65% | |================================================= | 70% | |==================================================== | 75% | |======================================================== | 80% | |============================================================ | 85% | |=============================================================== | 90% | |================================================================== | 95% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_MTORC1_SIGNALING | 0.0000000 | 0.0000000 | 1.0073180 | 0.5716615 | 2.4210066 | 194 | PSAT1;FADS2;PDK1;DDIT4;EGLN3;TRIB3;PHGDH;IFI30;P4HA1;TMEM97;DHCR7;TUBA4A;PSPH;MTHFD2;PNP;TFRC;DHCR24;SDF2L1;GPI;GSR;PGK1;BUB1;AURKA;PSMB5;PIK3R3;SHMT2;ME1;IDH1;LDHA;NAMPT;RRM2;CXCR4;DAPP1;ASNS;ACTR3;SQLE;GAPDH;BCAT1;CTSC;PLOD2;VLDLR;CALR;UFM1;ENO1;AK4;MAP2K3;SLC1A5;SRD5A1;MCM4;TES;SLC2A3;HK2;GMPS;PSMG1;UNG;LDLR;SSR1;ITGB2;GLRX;HMGCS1;HSP90B1;NFIL3;GBE1;PRDX1;PFKL;EBP;PITPNB;PPA1;FKBP2;TXNRD1;HSPD1;ARPC5L;CDC25A;TPI1;RDH11;XBP1;NUPR1;IDI1;PSMA3;HMBS;BTG2;TM7SF2 | significant |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | 0.0000000 | 0.0000000 | 0.9436322 | 0.5520072 | 2.3377701 | 194 | CCL7;CD38;SLAMF7;IRF5;PFKP;IRF4;PDE4B;CXCL9;TNFSF10;IFI30;MT2A;SOD2;ZBP1;ITGB7;STAT1;IDO1;MTHFD2;PNP;APOL6;CXCL10;CXCL11;ISG20;GBP4;HIF1A;UPP1;CASP7;CCL2;BATF2;ICAM1;NAMPT;IL2RB;LAP3;GCH1;HLA-B;CCL5;RSAD2;MX1;CASP8;CASP3;BANK1;CD274;TAP1;IFNAR2;HLA-DRB1;HLA-G;OASL;USP18;GZMA;IL6;B2M;SP110;PSME2;XCL1;CIITA;CD69;PSMB9;ISG15;BST2;IFIT2;FPR1;IL15RA;IL10RA;TRIM14;SAMD9L;IFIT3;NMI;NFKBIA;PNPT1;NCOA3;IRF8;IRF7;PSMA3;ST8SIA4;IRF2;VAMP5;PARP12;GBP6;PSMB10;PARP14 | significant |
| HALLMARK_INFLAMMATORY_RESPONSE | 0.0000000 | 0.0000000 | 0.9325952 | 0.5484666 | 2.3290909 | 197 | MARCO;CCL7;AQP9;ADM;PDE4B;CXCL9;TNFSF10;RNF144B;P2RY2;OLR1;ICAM4;EDN1;TLR2;SLC31A1;CCL20;CXCL10;CXCL11;HIF1A;CCL17;RGS1;OSM;KCNA3;CXCR6;CCL2;ICAM1;SLAMF1;IL18;NAMPT;PLAUR;SLC7A1;IL1R1;IL2RB;GCH1;CCL5;CXCL6;MSR1;IRAK2;CCR7;CCRL2;CYBB;FFAR2;IL6;CD55;SGMS2;LDLR;RGS16;PTGER4;CD69;P2RX7;IL18RAP;SLC31A2;PCDH7;CLEC5A;ATP2B1;PDPN;BST2;CD14;FPR1;C5AR1;IL15RA;IL10RA;CCL24;INHBA;EREG;CD70;LAMP3;NMI;IL1B;HBEGF;ROS1;ADORA2B;GPC3;NFKBIA;CD82;C3AR1;IL10;IRF7;TNFSF15;BTG2;SERPINE1;GPR183;TNFRSF9;OPRK1 | significant |
| HALLMARK_G2M_CHECKPOINT | 0.0000000 | 0.0000000 | 0.8634154 | 0.5364239 | 2.2618981 | 188 | CDC45;CDC20;MT2A;CDK1;HMGB3;KIF2C;UBE2C;CENPA;HMMR;HIF1A;BRCA2;E2F1;CCNB2;CENPF;BUB1;CDKN3;AURKA;RAD54L;TTK;EXO1;FBXO5;NASP;SLC7A1;BIRC5;MYBL2;SQLE;KIF23;NUSAP1;NDC80;NEK2;KIF11;KIF4A;CKS1B;RPS6KA5;RACGAP1;EGF;POLQ;TRAIP;KIF15;SMC4;EZH2;KPNA2;KIF5B;PTTG1;STIL;TRA2B;CENPE;CHEK1;MKI67;EFNA5;UCK2;SLC38A1;ODF2;RAD23B;CKS2;TOP2A;CCNA2;PRC1;BARD1;AURKB;BCL3;NOLC1;E2F2;CDC25A;MCM5;TPX2;LMNB1;E2F3;INCENP;DBF4;MAD2L1;TROAP;KIF20B;ORC6;DTYMK;UPF1;NCL;PLK1;HUS1;SAP30;STMN1;LBR;HMGA1;SMARCC1;NUP50 | significant |
| HALLMARK_ALLOGRAFT_REJECTION | 0.0000000 | 0.0000000 | 0.8266573 | 0.5138500 | 2.1759449 | 195 | CCL7;GZMB;CCL4;IRF4;DEGS1;CD79A;CXCL9;CXCL13;IFNG;FCGR2B;CCR1;STAT1;TLR2;HLA-E;CTSS;HIF1A;CCR2;CCL13;IL12A;TGFB2;SRGN;CD2;CCL2;FASLG;IL13;ICAM1;IL18;FGR;IL2RB;BCAT1;CCL5;NCF4;TAP1;IFNAR2;HLA-G;CCR5;INHBB;IL2RA;CD80;GBP2;KLRD1;GZMA;IL6;B2M;ITGB2;HLA-DOB;CD3D;CD3G;CCL11;IL18RAP;TRAT1;EIF3A;IGSF6;MBL2;INHBA;EREG;CAPG;HLA-DRA;BCL3;IL1B;EIF3D;GALNT1;IL2RG;MRPL3;IL2;HLA-DMB;IL10;BCL10;RPS19;IRF8;TLR6;IRF7;CXCR3;ST8SIA4;PTPRC;PSMB10;IFNGR1;HLA-A;NOS2;CD96;ABCE1;HDAC9;IL7;ICOSLG;CD247;PRF1;RIPK2;HLA-DMA;ABI1;ELANE;CD7;TLR1;C2;RPL9 | significant |
| HALLMARK_E2F_TARGETS | 0.0000000 | 0.0000000 | 0.8012156 | 0.5028306 | 2.1292821 | 195 | SPAG5;CCNE1;E2F8;CDC20;CDK1;MELK;HMGB3;KIF2C;MTHFD2;DLGAP5;TFRC;HMMR;TRIP13;BRCA2;CCNB2;CDKN3;AURKA;UBE2T;TK1;RRM2;CDCA8;NASP;BIRC5;PRDX4;MYBL2;ATAD2;RAD51AP1;MCM4;CTPS1;KIF4A;CKS1B;NCAPD2;GINS1;RANBP1;PAICS;RACGAP1;CHEK2;DEPDC1;UNG;SMC4;PRPS1;EZH2;KPNA2;PTTG1;TRA2B;CENPE;CHEK1;MKI67;DIAPH3;EIF2S1;CKS2;TOP2A;BARD1;AURKB;NOLC1;CDC25A;MCM5;LMNB1;BUB1B;MAD2L1;CDCA3;RFC3;ORC6;PPM1D;SPC25;MXD3;RAD1;PLK1;HUS1;STMN1;XRCC6;LBR;SPC24;EXOSC8;HMGA1;ASF1A;ORC2;CENPM;DEK;MLH1;TIMELESS | significant |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.0000001 | 0.0000004 | 0.7049757 | 0.4679128 | 1.9870152 | 197 | PHLDA2;CCL4;PDE4B;CXCL1;DUSP4;SOD2;KYNU;OLR1;B4GALT5;CEBPB;EDN1;TLR2;CCL20;CXCL10;CXCL11;SGK1;PLAU;DUSP5;CCL2;ICAM1;IL18;NAMPT;PLAUR;BCL2A1;GCH1;CCL5;VEGFA;CXCL6;MAP2K3;TAP1;CD80;SLC2A3;CCRL2;IL6;ZFP36;PANX1;LDLR;NR4A2;FOS;TNFAIP8;TRIB1;PTGER4;CSF2;CD69;NFIL3;F2RL1;CXCL2;ATP2B1;SLC2A6;IFIT2;EGR1;CFLAR;CXCL3;IL15RA;FUT4;ID2;INHBA;PFKFB3;IER2;LITAF;BCL3;IL1B;HBEGF;HES1;RCAN1;NFKBIA;SAT1;DUSP2;KLF9;BTG2;SERPINE1;MCL1;GPR183;SERPINB8;TNFRSF9 | significant |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | 0.0000329 | 0.0001371 | 0.5573322 | 0.5094589 | 1.9402025 | 94 | IFI30;CXCL10;CXCL11;ISG20;GBP4;BATF2;HLA-C;LAP3;RSAD2;MX1;CASP8;TAP1;OASL;GBP2;CCRL2;USP18;B2M;SP110;PSME2;PSMB9;ISG15;BST2;IFIT2;TRIM14;SAMD9L;LAMP3;IFIT3;NMI;PNPT1;NCOA7;IRF7;PSMA3;IRF2;PARP12;PARP14;IFIH1;PLSCR1;IL7;RIPK2;TRIM5 | significant |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.0001059 | 0.0003781 | 0.5384341 | 0.4966328 | 1.8815764 | 87 | CCL7;CD38;CXCL9;CXCL1;CXCL13;CCR1;STAT1;TNFRSF21;TLR2;CXCL10;CXCL11;TNFRSF12A;HMOX1;IL1R1;IL2RA;IL6;IL13RA1;CSF2;CD14;CXCL3;IL15RA;IL1B;IL2RG | significant |
| HALLMARK_GLYCOLYSIS | 0.0000014 | 0.0000070 | 0.6435518 | 0.4418003 | 1.8761272 | 197 | ANGPTL4;GPC4;PFKP;DDIT4;B3GNT3;EGLN3;P4HA1;CDK1;SLC16A3;SRD5A3;SDC1;GNE;SPAG4;CENPA;HMMR;ISG20;PGK1;AURKA;GALE;AKR1A1;ME1;IDH1;LDHA;CXCR4;MIF;CITED2;NASP;MED24;PLOD2;VLDLR;VEGFA;ENO1;AK4;PKP2;HK2;BPNT1;IL13RA1;PYGB;DEPDC1;KDELR3;CHST1;GLRX;PRPS1;PGLS;TXN;COPB2;KIF20A;FBP2;SLC25A13;NDST3;HDLBP;LDHC;LHPP;CHST12;ADORA2B;GPC3;TPI1;GMPPA;HS6ST2;AGRN;GMPPB;CLDN9;CHPF;CHST2;LHX9;PDK3;CASP6;SAP30;G6PD;STMN1 | significant |
| HALLMARK_HYPOXIA | 0.0000993 | 0.0003781 | 0.5384341 | 0.4185119 | 1.7639719 | 191 | ANGPTL4;TMEM45A;CP;ADM;PDK1;GPC4;PFKP;EDN2;DDIT4;MT2A;P4HA1;ISG20;GPI;PGK1;ERRFI1;LDHA;PLAUR;NDRG1;CXCR4;MIF;CITED2;WSB1;HMOX1;GAPDH;SLC2A5;PLIN2;VLDLR;VEGFA;ENO1;AK4;B4GALNT2;TES;SLC2A3;TPST2;FBP1;HK2;IL6;ZFP36;KDELR3;GLRX;FOS;PLAC8;MT1E;NFIL3;GBE1;PFKL;HS3ST1;TGM2;PFKFB3;HDLBP;KLF7;LDHC;ADORA2B;GPC3;HOXB9;TPI1 | significant |
| HALLMARK_COMPLEMENT | 0.0002230 | 0.0007433 | 0.5188481 | 0.3981679 | 1.6948139 | 198 | S100A9;DUSP6;CP;GZMB;PDP1;PRSS36;CXCL1;PLA2G7;APOC1;KYNU;OLR1;PHEX;CEBPB;CPM;CTSS;F7;CD46;CASP7;C1QA;DUSP5;FN1;ME1;PLAUR;CTSD;GPD2;CA2;LAP3;CTSC;CCL5;C1QC;CASP3;FCER1G;GZMA;ITGAM;IL6;CD55;CASP10;MMP13;PIK3CG;PSMB9 | significant |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 0.0054628 | 0.0136569 | 0.4070179 | 0.4564869 | 1.6694648 | 72 | FADS2;TRIB3;TMEM97;DHCR7;CBS;TNFRSF12A;MAL2;ECH1;ERRFI1;PLAUR;SQLE;SREBF2;S100A11;FDPS;LDLR;HMGCS1;TP53INP1;ALCAM;NFIL3;MVD;FASN;EBP;LGALS3;IDI1;LSS;TM7SF2;CXCL16;ETHE1;PDK3;PLSCR1 | significant |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.0015868 | 0.0046671 | 0.4550599 | 0.4314078 | 1.6689450 | 106 | PSAT1;DDIT4;CEBPB;SPCS3;MTHFD2;HERPUD1;NABP1;CCL2;ASNS;ATF4;DNAJB9;CALR;VEGFA;EIF4EBP1;EIF2AK3;CKS1B;KDELR3;SSR1;WIPI1;HSP90B1;KIF5B;YWHAZ;XPOT;EIF2S1;NOLC1;CHAC1;XBP1;PDIA5;ERN1;DNAJC3;EDEM1;ALDH18A1;POP4;YIF1A | significant |
| HALLMARK_MYC_TARGETS_V2 | 0.0256949 | 0.0494132 | 0.3524879 | 0.4488406 | 1.5769026 | 57 | TMEM97;MCM4;HK2;SLC19A1;GNL3;UNG;SRM;IMP4;IPO4;HSPD1;NOLC1;MCM5;DUSP2;RCL1;MRTO4;SLC29A2;DDX18;PLK1;CBX3;NIP7;MAP3K6 | significant |
| HALLMARK_MYC_TARGETS_V1 | 0.0036662 | 0.0096478 | 0.4317077 | 0.3654627 | 1.5454595 | 193 | PSMD3;PABPC1;CDC45;CDC20;TYMS;PGK1;LDHA;PRDX4;EEF1B2;MCM4;CTPS1;RPS5;RANBP1;AP3S1;GNL3;SRM;KPNA2;HDAC2;TRA2B;XPOT;EIF2S1;RAD23B;PABPC4;CCNA2;HSPD1;UBE2L3;EIF3D;NOLC1;MCM5;PSMD8;MAD2L1;SRPK1;EXOSC7;PSMD7;SNRPD3;U2AF1;RFC4;DDX18;RPS6;SNRPG;IMPDH2;CBX3;SET;PSMD14;ABCE1;XRCC6;RPS10;SMARCC1;DDX21;ORC2;DEK;HNRNPA3;EIF4A1;PSMA6;PSMA2;XPO1;SYNCRIP;FBL;BUB3;RPS3;CAD;HSPE1;NCBP1;C1QBP;MCM7;CCT4;SSB;MCM6;POLE3;ACP1;PA2G4;RPL6;COX5A;EIF2S2;HNRNPR;IFRD1;CANX;RPL14;UBA2;CSTF2;NOP56;ODC1;PSMB3;SRSF7 | significant |
| HALLMARK_MITOTIC_SPINDLE | 0.0017057 | 0.0047382 | 0.4550599 | 0.3613035 | 1.5342935 | 197 | CDK1;TUBA4A;KIF2C;ANLN;DLGAP5;DYNLL2;BRCA2;ECT2;CCNB2;CENPF;ARHGAP27;BUB1;AURKA;TUBD1;PIF1;TTK;FBXO5;BIRC5;KIF23;CDC42EP1;NUSAP1;NDC80;NEK2;KIF11;KIF4A;SHROOM1;RACGAP1;STK38L;KIF15;CSNK1D;EZR;SMC4;KIF5B;CENPE;RAB3GAP1;MYO9B;MID1;TOP2A;PRC1;SHROOM2;TPX2;SSH2;LMNB1;INCENP;RANBP9;FGD4;KIF20B;PPP4R2;MAP1S | significant |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 0.0147997 | 0.0308327 | 0.3807304 | 0.3914900 | 1.5097272 | 104 | PDK1;TRIB3;CDK1;E2F1;PIK3R3;FASLG;PRKAA2;CXCR4;DAPP1;ACTR3;CALR;PLCB1;MAP2K3;HSP90B1;MAP2K6;IL2RG;MAPK1;CLTC;NGF;ARF1;ACTR2;DDIT3;SFN;PPP2R1B;MAPK10;PTPN11;TIAM1;FGF17;CAB39L;MAPK9;FGF22;MYD88;IL4 | significant |
| HALLMARK_IL2_STAT5_SIGNALING | 0.0066093 | 0.0157363 | 0.4070179 | 0.3489849 | 1.4779635 | 194 | SPP1;IRF4;CCNE1;TNFSF10;P4HA1;PNP;TNFRSF21;CXCL10;GBP4;PTRH2;CTLA4;IL13;TTC39B;ETV4;NDRG1;ENPP1;IL2RB;ICOS;CA2;PLIN2;CASP3;SLC1A5;IL2RA;SPRED2;SLC2A3;HK2;CD79B;BATF;RGS16;ALCAM;CSF2;NFIL3;GLIPR2;CKAP4;UCK2;SPRY4;TGM2;IL10RA;CAPG;PRKCH;LCLAT1;IL10;NCOA3;CDCP1;PDCD2L;TNFRSF8;XBP1;IRF8;ADAM19;SLC29A2;SLC39A8;TNFRSF9;IFNGR1 | significant |
| HALLMARK_ANDROGEN_RESPONSE | 0.0135917 | 0.0295471 | 0.3807304 | 0.3827311 | 1.4604019 | 96 | DBI;LMAN1;SPDEF;SPCS3;UBE2J1;TMPRSS2;DHCR24;SGK1;GSR;NDRG1;UAP1;PGM3;DNAJB9;CENPN;MYL12A;ELL2;B2M;NGLY1;HMGCS1;ABCC4;TNFAIP8;MAK;SLC38A2;SEC24D;SAT1;IDI1;RAB4A;FKBP5;APPBP2;INSIG1 | significant |
| HALLMARK_XENOBIOTIC_METABOLISM | 0.0097038 | 0.0220542 | 0.3807304 | 0.3416772 | 1.4470148 | 194 | HSD17B2;ACOX2;AQP9;ABCC3;PAPSS2;MT2A;XDH;HSD11B1;TMEM97;KYNU;COMT;TDO2;NQO1;SPINT2;UPP1;GSR;TGFB2;GNMT;ECH1;SHMT2;PYCR1;IDH1;ARG2;HMOX1;IL1R1;BCAT1;DDT;CA2;GCH1;TTPA;SLC1A5;FBP1;APOE | significant |
| HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY | 0.0549928 | 0.0886980 | 0.2311267 | 0.4178187 | 1.4151140 | 47 | PFKP;SOD2;NQO1;MGST1;GSR;PRDX4;FTL;GLRX;PRDX1;TXN;TXNRD1;TXNRD2;PRDX6;G6PD;IPCEF1 | non-significant |
| HALLMARK_KRAS_SIGNALING_UP | 0.0354430 | 0.0632911 | 0.2712886 | 0.3177802 | 1.3394012 | 191 | DUSP6;ANGPTL4;SPP1;MYCN;GALNT3;ADAMDEC1;ST6GAL1;HSD11B1;ADAM8;PLEK2;CCL20;CXCL10;CTSS;TLR8;PLAU;MPZL2;PLAUR;ETV4;CXCR4;PRDM1;CA2;LAPTM5;FCER1G;TRIB2;AMMECR1;ITGB2;GLRX;RGS16;TRIB1;PDCD1LG2;CSF2;CFHR2;F2RL1;IL10RA;ID2;INHBA;EREG;PCP4;GPNMB;IL1B;HBEGF;IL2RG;MMP11;C3AR1 | non-significant |
| HALLMARK_UV_RESPONSE_UP | 0.0676393 | 0.1056863 | 0.1978220 | 0.3137080 | 1.2802817 | 154 | STARD3;CCNE1;SOD2;GAL;TUBA4A;TFRC;ICAM1;BID;PARP2;AQP3;ASNS;HMOX1;PDLIM3;AP2S1;POLR2H;CA2;EPCAM;GCH1;GGH;CASP3;TAP1;CHRNA5;LHX2;IL6;AGO2;ACAA1;FOS | non-significant |
| HALLMARK_PEROXISOME | 0.1547779 | 0.2149693 | 0.1268757 | 0.3116182 | 1.2017127 | 104 | CRAT;PABPC1;SOD2;CRABP1;IDH2;DHCR24;ACSL1;ECH1;NUDT19;IDH1;SLC25A19;FABP6;TSPO;CTPS1;FDPS;ACAA1;SLC25A17;PRDX1;TOP2A;IDE;RDH11;BCL10;IDI1;YWHAH;SCGB1A1;UGT2B17 | non-significant |
| HALLMARK_COAGULATION | 0.1865966 | 0.2332457 | 0.1123785 | 0.2894384 | 1.1654989 | 137 | FGG;MMP1;DUSP6;ACOX2;HMGCS2;APOC1;F12;OLR1;MMP3;C1QA;PLAU;COMP;FN1;CAPN2;PROZ;FGA;ARF4;CTSE;SH2B2;APOC2;THBS1;MBL2 | non-significant |
| HALLMARK_KRAS_SIGNALING_DN | 0.1683544 | 0.2275060 | 0.1167392 | 0.2759224 | 1.1629763 | 191 | PNMT;TFAP2B;AKR1B10;PRODH;CALML5;EDN2;IFNG;SPRR3;RIBC2;EDN1;SGK1;TGFB2;PDCD1;ENTPD7;RSAD2;MX1;CD80;MFSD6;SPTBN2;EGF;NR4A2;TCL1A;KRT4;THRB;SLC30A3;LFNG;GPR19;CCR8;BARD1;CYP11B2;YPEL1;SIDT1;SCN10A;SERPINA10;GPR3;CAMK1D;BTG2;ATP4A;NR6A1;SCGB1A1;UGT2B17;ABCB11;ALOX12B;ARPP21;ITGB1BP2;CHST2;CLPS | non-significant |
| HALLMARK_APOPTOSIS | 0.2015707 | 0.2458179 | 0.1071402 | 0.2801566 | 1.1511715 | 159 | ERBB2;CD38;TNFSF10;SOD2;ISG20;CASP7;TNFRSF12A;GSR;TGFB2;CD2;FASLG;IL18;BID;HMOX1;GCH1;TSPO;CASP8;CASP3;TAP1;IL6;CD69;GPX1;EBP;CD14;LGALS3;CFLAR;EREG;TOP2A | non-significant |
| HALLMARK_SPERMATOGENESIS | 0.2951886 | 0.3514149 | 0.0843144 | 0.2728018 | 1.0956431 | 132 | DPEP3;CRISP2;CDK1;KIF2C;CCNB2;BUB1;CDKN3;AURKA;TTK;PARP2;SLC2A5;OAZ3;NEK2;ADAD1;PSMG1;EZH2;NCAPH;TNP1;AGFG1;LDHC;GAD1;TNP2;IDE;DBF4;DMRT1;RFC4;PGK2;GFI1;PRM2;DNAJB8;ODF1;COIL;PDHA2;GMCL1;NOS1;MEP1B;ELOVL3;TUBA3C;PAPOLB;DMC1;GRM8;HTR5A;AKAP4;CLPB;DDX4;ARL4A;ZPBP;CLVS1;ZNRF4;MTNR1A;TSSK2 | non-significant |
| HALLMARK_P53_PATHWAY | 0.4088608 | 0.4754195 | 0.0661326 | 0.2447962 | 1.0317832 | 191 | CLCA2;TRAF4;DDIT4;TRIB3;IFI30;SDC1;VDR;UPP1;STEAP3;MAPKAPK3;ALOX15B;NDRG1;PERP;CTSD;HMOX1;NUDT15;TAP1;INHBB;GM2A;ITGB4;RGS16;FOS | non-significant |
| HALLMARK_FATTY_ACID_METABOLISM | 0.4776903 | 0.5428299 | 0.0603786 | 0.2423714 | 0.9906777 | 152 | HMGCS2;CRAT;IL4I1;TDO2;DHCR24;ACSL1;ECH1;ME1;IDH1;LDHA;MIF;GPD2;CA2;CBR3;ACSS1;FABP2;ACAA1;HMGCS1;FASN;ACADL;CPT1A | non-significant |
| HALLMARK_PROTEIN_SECRETION | 0.5638298 | 0.6264775 | 0.0532386 | 0.2525287 | 0.9617201 | 94 | LMAN1;BNIP3;OCRL;AP2S1;CTSC;ARFGAP3;SGMS1;AP3S1;COPB2;COPE;ADAM10;SEC24D;RAB5A;RAB2A;SH3GL2;MAPK1;ICA1;CLTC;ARF1 | non-significant |
| HALLMARK_DNA_REPAIR | 0.9456954 | 0.9649953 | 0.0289274 | 0.1801818 | 0.7325841 | 145 | PDE4B;CCNO;PNP;ZWINT;TYMS;POLR2H;RAD51;NELFB;ADA;POLR2K;NT5C3A;GUK1;RBX1;RFC3;RALA;PDE6G;RFC4;POLR2I;POLR2D;IMPDH2;PRIM1;SEC61A1;TAF13;RAD52;ELL;SNAPC4;STX3 | non-significant |
| HALLMARK_APICAL_SURFACE | 0.8798842 | 0.9360470 | 0.0366850 | 0.2152099 | 0.7208213 | 43 | FLOT2;PLAUR;IL2RB;EFNA5;ADAM10;IL2RG;SHROOM2;EPHB4;PKHD1;SLC34A3;CD160;RHCG;NTNG1;CX3CL1;SLC22A12;LYN | non-significant |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.9974619 | 0.9974619 | 0.0238623 | 0.1399962 | 0.5866597 | 184 | PDP1;IDH2;OAT;CASP7;GPI;ECH1;IDH1;LDHA;SLC25A5;ACAA1;UQCRFS1;CPT1A;RHOT1;TIMM17A | non-significant |
| HALLMARK_HEME_METABOLISM | 0.9029126 | 0.9405340 | 0.0956031 | -0.1708860 | -0.8216711 | 189 | NFE2;HBD;HAGH;ALAS2;C3;DMTN;LMO2;HBB;ABCG2;TRIM58;EZH1;TRAK2;ADD1;UROD;MOCOS;XK;TSPAN5;VEZF1;SNCA;SELENBP1;CCND3;ALAD;BTRC;HEBP1;HBQ1;ACSL6;TMCC2;PIGQ;CPOX | non-significant |
| HALLMARK_TGF_BETA_SIGNALING | 0.6531987 | 0.7099985 | 0.0931455 | -0.2351449 | -0.9030487 | 54 | CDKN1C;SMAD3;BCAR3;NCOR2;SKIL;TGFB1;ID3;HDAC1;FKBP1A;LTBP2;ID1;TJP1;KLF10;ENG;RAB31;HIPK2;FURIN | non-significant |
| HALLMARK_BILE_ACID_METABOLISM | 0.1250000 | 0.1838235 | 0.2572065 | -0.2708372 | -1.2068717 | 112 | SLC27A2;ABCA3;TFCP2L1;ABCA5;SERPINA6;SLC27A5;CH25H;NUDT12;BCAR3;ABCA6;PFKM;LIPE;HSD17B4;SLC29A1;PXMP2;ISOC1;PEX19;PEX12;PEX6;FDXR;PEX11A;DIO1;GSTK1;EPHX2;SLC23A2 | non-significant |
| HALLMARK_HEDGEHOG_SIGNALING | 0.1854103 | 0.2332457 | 0.1797823 | -0.3523276 | -1.2180266 | 35 | HEY2;GLI1;NRCAM;HEY1;RTN1;DPYSL2;CRMP1;CELSR1;ETS2;CNTFR;RASA1 | non-significant |
| HALLMARK_ADIPOGENESIS | 0.0410896 | 0.0708441 | 0.3217759 | -0.2560614 | -1.2369430 | 192 | CYP4B1;SPARCL1;ITGA7;PTGER3;LPL;HSPB8;C3;GPAM;SCARB1;NMT1;ADCY6;LIFR;STOM;LIPE;ADIPOR2;ACADS;PHLDB1;PEMT;REEP5;LEP;CDKN2C;HADH;QDPR;ENPP2;COL15A1;DGAT1;SULT1A1;TOB1;MYLK;CD302;LTC4S;ARAF;CMBL;GADD45A;STAT5A;CYC1;PDCD4;EPHX2;GPHN;IDH3A;DHRS7B;NDUFAB1;DHRS7;COL4A1;DNAJC15;ANGPT1;COQ5;SORBS1;CD36 | non-significant |
| HALLMARK_NOTCH_SIGNALING | 0.1849711 | 0.2332457 | 0.1752040 | -0.3650008 | -1.2494887 | 32 | JAG1;CCND1;HEYL;KAT2A;PRKCA;SKP1;DTX1;DLL1;APH1A | non-significant |
| HALLMARK_PANCREAS_BETA_CELLS | 0.1481481 | 0.2116402 | 0.2042948 | -0.3514461 | -1.2546482 | 40 | SYT13;ABCC8;CHGA;LMO2;INSM1;DCX;PCSK1;SRP14;DPP4 | non-significant |
| HALLMARK_APICAL_JUNCTION | 0.0236679 | 0.0473358 | 0.3524879 | -0.2799674 | -1.3469443 | 190 | CD86;IRS1;CALB2;CLDN5;EVL;COL17A1;SLIT2;LAMB3;GAMT;WNK4;TRO;LAMC2;CLDN11;AMIGO2;ITGA10;SRC;NLGN2;FSCN1;NRXN2;THBS3;LAMA3;COL16A1;VWF;HADH;SGCE;PBX2;CD34;MDK;LAYN;ITGA3;STX4;KCNH2;AMIGO1;ACTG2;ADAMTS5;ADRA1B;CTNNA1 | significant |
| HALLMARK_ANGIOGENESIS | 0.0704453 | 0.1067353 | 0.2878051 | -0.3932791 | -1.3626722 | 36 | SERPINA5;LPL;JAG1;COL3A1;MSX1;KCNJ8;CCND2;FSTL1;POSTN;PTK2;VCAN;TIMP1;FGFR1 | non-significant |
| HALLMARK_UV_RESPONSE_DN | 0.0440917 | 0.0734861 | 0.3217759 | -0.2966159 | -1.3724966 | 138 | IGF1R;IRS1;GJA1;CAV1;CACNA1A;COL3A1;CDON;SMAD3;PTPRM;PRKCA;LAMC1;PDGFRB;APBB2;COL1A1;NIPBL;SRI;FYN;FBLN5;DBP;PMP22;COL1A2;PHF3;PRKCE;PTPN21;CAP2;FZD2;GRK5;MAP1B;KIT;AGGF1;MMP16;DLC1;RUNX1;EFEMP1;MGMT;ID1;MAGI2;LPAR1;BHLHE40;TJP1;YTHDC1;TGFBR3;TGFBR2 | non-significant |
| HALLMARK_WNT_BETA_CATENIN_SIGNALING | 0.0305470 | 0.0565685 | 0.3524879 | -0.4309539 | -1.5435261 | 42 | HEY2;FZD8;JAG1;NOTCH4;HDAC5;KAT2A;HEY1;LEF1;NCOR2;DLL1;CCND2;AXIN1;TCF7 | non-significant |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 0.0003024 | 0.0009449 | 0.4984931 | -0.3364986 | -1.6304420 | 195 | SFRP1;AREG;LAMA2;GJA1;SFRP4;IGFBP4;SLIT2;TFPI2;FZD8;DST;GEM;COL3A1;LAMC2;HTRA1;ANPEP;PDLIM4;MATN3;LAMC1;COL5A3;PFN2;COL6A2;PDGFRB;LAMA3;PCOLCE2;COL1A1;MGP;PTX3;GPC1;COL16A1;EFEMP2;COL7A1;FBLN1;CD59;SPARC;ELN;ECM1;SDC4;MSX1;MYLK;FBLN5;PMP22;BASP1;ECM2;COL1A2;PCOLCE;SGCD;SGCB;FBN2;SGCG;TGFB1;FSTL1;POSTN;GADD45A;IGFBP3;VCAN;CAP2;COL6A3 | significant |
| HALLMARK_MYOGENESIS | 0.0000023 | 0.0000106 | 0.6272567 | -0.3957007 | -1.9075130 | 196 | CRYAB;STC2;APOD;LAMA2;MYH11;CLU;ITGA7;MYOM2;PPP1R3C;SH3BGR;HSPB8;TNNC2;COL3A1;HSPB2;ADCY9;GSN;HDAC5;FKBP1B;IGF1;PFKM;AGL;COL6A2;PVALB;BIN1;COL1A1;BAG1;SPARC;FHL1;SOD3;TNNT3;MRAS;SH2B1;COL15A1;TSC2;HRC;IGFBP7;CTF1;MYLK;PKIA;KCNH2;SGCD;FST;SPTAN1;SGCG;TGFB1;GABARAPL2;CAMK2B;IGFBP3;RIT1;MYOM1;FXYD1;COL6A3;COX7A1;RYR1;ANKRD2;CACNG1;CFD;PGAM2;CACNA1H;SORBS1;CD36;COL4A2;EIF4A2 | significant |
| HALLMARK_ESTROGEN_RESPONSE_LATE | 0.0000000 | 0.0000000 | 0.9214260 | -0.5056151 | -2.4424493 | 192 | PDZK1;NPY1R;SERPINA5;SERPINA3;AREG;SLC27A2;DHRS2;DNAJC12;SCUBE2;CHST8;MAPT;GPER1;ABCA3;NRIP1;COX6C;BCL2;PGR;CELSR2;CXCL14;IGSF1;PTGER3;TPSAB1;MYB;RBBP8;IGFBP4;CPE;CHPT1;TFPI2;SIAH2;IL6ST;FLNB;CAV1;HSPB8;SLC22A5;KLK10;AMFR;ANXA9;LAMC2;CCND1;CA12;SORD;CACNA2D2;SCARB1;SCNN1A;IL17RB;LTF;SERPINA1;PRSS23;KRT13;CYP26B1;SLC29A1;ABHD2;ELOVL5;SOX3;ARL3;HSPA4L;BAG1;OLFM1 | significant |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | 0.0000000 | 0.0000000 | 1.2790340 | -0.6204304 | -2.9849373 | 190 | PDZK1;NPY1R;MSMB;ELOVL2;SLC39A6;AREG;SLC27A2;DHRS2;STC2;MAPT;ABCA3;NRIP1;IGF1R;SLC7A2;RHOBTB3;BCL2;PGR;SYBU;CELSR2;GJA1;CALB2;OLFML3;SLC19A2;THSD4;MYB;RBBP8;KRT15;IGFBP4;CHPT1;PMAIP1;SIAH2;IL6ST;FLNB;GFRA1;ADCY1;SLC1A1;HSPB8;SLC22A5;KLK10;AMFR;ANXA9;PODXL;KRT8;CCND1;UGCG;CA12;ADCY9;SCARB1;CBFA2T3;ABAT;SCNN1A;KCNK15;MPPED2;IL17RB;PRSS23;KRT13;GREB1;CYP26B1;MAST4;ABHD2;ELOVL5;SOX3;ARL3;ZNF185;ASB13;KRT18;BAG1;OLFM1;TUBB2B;ELF3;GAB2;SEC14L2;NCOR2;MED13L;MYBL1;TOB1;DYNLT3 | significant |
KEGG_MEDICUS Pathway Analysis
no significant pathways for targetd
fgsea_kegg_result_list <- list()
fgsea_kegg_barplot_list <- list()
fgsea_kegg_dotplot_list <- list()
for (treatment in names(top_table_list)) {
message("Running KEGG GSEA for: ", treatment)
# Ranked gene list
top_full <- top_table_list[[treatment]]
ranks <- setNames(top_full$logFC, top_full$Gene)
ranks <- sort(ranks, decreasing = TRUE)
# Run fgsea
fgseaRes_kegg <- fgsea(pathways = pathwaysKEGG_MED, stats = ranks, nproc = 1)
fgseaRes_kegg <- na.omit(fgseaRes_kegg)
# Format tidy results
fgseaResTidy_kegg <- fgseaRes_kegg %>%
as_tibble() %>%
arrange(desc(NES)) %>%
mutate(
leadingEdge = sapply(leadingEdge, paste, collapse = ";"),
adjPvalue = ifelse(padj <= 0.05, "significant", "non-significant")
)
fgsea_kegg_result_list[[treatment]] <- fgseaResTidy_kegg
write.table(
fgseaResTidy_kegg,
file.path(output_dir, "pathway_analysis", paste0(gsub("\\+", "_", treatment), "_fgseaRes_kegg.txt")),
sep = "\t", row.names = FALSE, quote = FALSE
)
sig_fgsea <- fgseaResTidy_kegg %>% filter(padj <= 0.05)
# --- Plot 1: Bar plot of significant NES ---
p_bar <- ggplot(sig_fgsea, aes(reorder(pathway, NES), NES, fill = adjPvalue)) +
geom_col() +
scale_fill_manual(values = c("significant" = "red")) +
coord_flip() +
theme_minimal() +
labs(
x = "Pathway", y = "Normalized Enrichment Score (NES)",
title = paste("KEGG NES -", treatment)
)
fgsea_kegg_barplot_list[[treatment]] <- p_bar
print(p_bar)
# --- Plot 2: Dot plot by size and padj ---
p_dot <- ggplot(sig_fgsea, aes(y = reorder(pathway, size), x = NES)) +
geom_point(aes(color = padj, size = size)) +
scale_color_gradientn(colours = c("red", "blue")) +
labs(x = "NES", y = NULL, title = paste("KEGG Dot Plot -", treatment)) +
theme(axis.title = element_text(face = 'bold'), axis.text = element_text(face = 'bold'))
fgsea_kegg_dotplot_list[[treatment]] <- p_dot
print(p_dot)
# --- Optional table display ---
print(
kable(fgseaResTidy_kegg, caption = paste("KEGG GSEA results -", treatment)) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE) %>%
scroll_box(height = "400px")
)
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| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8986712 | 0.7678239 | 3.0799630 | 35 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PRNP;PSMD11;PSMD8;PSMD6 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8986712 | 0.7678059 | 3.0798906 | 35 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;APP;PSMD11;PSMD8;PSMD6 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8986712 | 0.7392802 | 3.0546581 | 40 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;UBA52;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;SOD1;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6;UBC;PSMD1;RPS27A;UBB | significant |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8870750 | 0.7488328 | 3.0541805 | 38 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;UBA52;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6;UBC;PSMD1;RPS27A;UBB | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8986712 | 0.7426800 | 3.0488663 | 39 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;UBA52;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6;UBC;PSMD1;RPS27A;UBB | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8986712 | 0.7407616 | 3.0409908 | 39 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;UBA52;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6;UBC;PSMD1;RPS27A;UBB | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8266573 | 0.7329566 | 2.9401002 | 35 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0000000 | 0.0000000 | 0.8266573 | 0.7314598 | 2.9340959 | 35 | PSMA4;PSMA7;PSMC3;ADRM1;PSMB1;PSMD2;PSMB3;PSMD13;PSMC4;PSMC2;PSMD14;PSMC5;PSMB6;PSMB2;PSMA5;PSMB7;PSMA2;PSMB4;PSMA1;PSMD12;PSMB5;PSMA3;PSMD7;PSMA6;PSMD4;PSMD11;PSMD8;PSMD6 | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES | 0.0000000 | 0.0000000 | 0.8513391 | 0.9304779 | 2.8364943 | 13 | HLA-DRB5;HLA-DQA2;HLA-DRB1;HLA-DRA;HLA-DMA;HLA-DPA1;HLA-DQA1;HLA-DQB1;HLA-DPB1;CD74;HLA-DOB;HLA-DMB;HLA-DOA | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION | 0.0000000 | 0.0000001 | 0.7881868 | 0.9072104 | 2.7655651 | 13 | HLA-DRB5;HLA-DQA2;HLA-DRB1;HLA-DRA;HLA-DMA;HLA-DPA1;HLA-DQA1;HLA-DQB1;HLA-DPB1;HLA-DOB;HLA-DMB;HLA-DOA | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000006 | 0.0000251 | 0.6594444 | 0.8703801 | 2.5970017 | 12 | HLA-F;HLA-A;TAP1;HLA-E;HLA-C;HLA-B;B2M | significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY | 0.0000004 | 0.0000190 | 0.6749629 | 0.8418403 | 2.5824971 | 14 | ARPC1B;ACTR3;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 0.0000030 | 0.0001031 | 0.6272567 | 0.8194333 | 2.4979828 | 13 | CCL4;CCL3;CCL5;CCL2;CX3CL1 | significant |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 0.0000018 | 0.0000691 | 0.6435518 | 0.6480235 | 2.4728573 | 30 | MCM5;RFC4;CDC45;MCM6;MCM2;POLA2;POLE3;MCM7;RFC2;POLE2;RFC5;MCM3;RPA2;PRIM2;PCNA;MCM4;MCM10;POLE4;GINS2;PRIM1 | significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 0.0000069 | 0.0002232 | 0.6105269 | 0.7163259 | 2.4677946 | 20 | ARPC1B;ACTR3;ARPC5L;ARPC5;ARPC2;ARPC4;BRK1;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE | 0.0000127 | 0.0003496 | 0.5933255 | 0.8233850 | 2.4567798 | 12 | TTK;NDC80;PPP1CA;SPC25;NUF2;SKA2;SPC24;SKA1;PPP1CB;SKA3;PPP1CC | significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY | 0.0000094 | 0.0002895 | 0.5933255 | 0.8013632 | 2.4428976 | 13 | ARPC1B;ACTR3;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0000170 | 0.0004373 | 0.5756103 | 0.7899388 | 2.4080709 | 13 | MMP1;CCL2;MMP3;CYBB;IL1B;TNF;ACE2 | significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0000184 | 0.0004554 | 0.5756103 | 0.6288997 | 2.3736143 | 29 | ARPC1B;ACTR3;ARPC5L;ARPC5;CYTH1;ARPC2;ARPC4;BRK1;NCKAP1L;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 0.0000302 | 0.0007201 | 0.5756103 | 0.6474924 | 2.3648131 | 24 | MCM5;CCNE1;CDC45;MCM6;MCM2;CCNA2;CDC7;MCM7;CDT1;ORC6;MCM3;TICRR;ORC3;ORC1;MCM4 | significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 0.0000973 | 0.0016274 | 0.5384341 | 0.7093015 | 2.3614668 | 17 | ARPC1B;ACTR3;NCK1;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;WIPF1;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 0.0000130 | 0.0003496 | 0.5933255 | 0.7272775 | 2.3511968 | 16 | CENPW;ZWINT;NDC80;BIRC5;CDCA8;SPC25;NUF2;PMF1;SPC24;INCENP | significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY | 0.0000564 | 0.0011631 | 0.5573322 | 0.7621488 | 2.3233554 | 13 | ARPC1B;ACTR3;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000001 | 0.0000079 | 0.6901325 | 0.9582162 | 2.3158311 | 7 | HLA-F;HLA-A;HLA-E;HLA-C;HLA-B;B2M | significant |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0000773 | 0.0014071 | 0.5384341 | 0.6764701 | 2.2939084 | 19 | CD3D;LCK;CD247;CD3G;VAV1;LCP2;ZAP70;CD4;LAT;PLCG2;ITPR3 | significant |
| KEGG_MEDICUS_REFERENCE_NON_CANONICAL_INFLAMMASOME_SIGNALING_PATHWAY | 0.0000006 | 0.0000251 | 0.6594444 | 0.9477080 | 2.2904346 | 7 | CASP1;IL18;CASP4;IL1B;CASP5 | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 0.0001216 | 0.0019301 | 0.5384341 | 0.6890832 | 2.2900803 | 18 | MCM5;CDC45;MCM6;MCM2;MCM7;RBX1;MCM3;MCM4;LRR1;UBB;GINS2;PIF1;VCP;GINS3;NPLOC4;CUL2 | significant |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0000611 | 0.0011880 | 0.5384341 | 0.6271161 | 2.2809479 | 25 | ARPC1B;ACTR3;ARPC5L;ARPC5;CYTH1;ARPC2;ARPC4;BRK1;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 0.0000704 | 0.0013199 | 0.5384341 | 0.6507889 | 2.2770746 | 21 | ARPC1B;ACTR3;EGFR;NCK1;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;WIPF1;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY | 0.0000918 | 0.0015776 | 0.5384341 | 0.7410559 | 2.2733226 | 14 | ARPC1B;ACTR3;ARPC5L;ARPC5;ARPC2;ARPC4;ACTB;ARPC1A;BAIAP2L1;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 0.0000335 | 0.0007687 | 0.5573322 | 0.6016535 | 2.2592957 | 27 | MCM5;CDC45;MCM6;MCM2;POLE3;MCM7;CDT1;ORC6;POLE2;MCM3;TICRR;TOPBP1;ORC3;ORC1;MCM4;POLE4;GINS2 | significant |
| KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.0000027 | 0.0000994 | 0.6272567 | 0.9338141 | 2.2568556 | 7 | C1QA;C1QB;C1QC;C1S;C2;C1R | significant |
| KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX | 0.0001053 | 0.0017160 | 0.5384341 | 0.7863353 | 2.2468250 | 11 | NDC80;AURKA;PPP1CA;SPC25;NUF2;CENPE;SPC24;PPP1CB;PPP1CC;SPAG5 | significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000003 | 0.0000154 | 0.6749629 | 0.9614338 | 2.2251033 | 6 | HLA-F;HLA-A;HLA-E;HLA-C;HLA-B | significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000106 | 0.0003131 | 0.5933255 | 0.9201546 | 2.2238433 | 7 | HLA-F;HLA-A;HLA-E;HLA-C;HLA-B;BCAP31 | significant |
| KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 0.0005182 | 0.0071179 | 0.4772708 | 0.7123633 | 2.1715876 | 13 | FDFT1;LBR;DHCR7;MSMO1;DHCR24;EBP;NSDHL;SQLE;LSS;CYP51A1 | significant |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0005211 | 0.0071179 | 0.4772708 | 0.6649186 | 2.1200487 | 15 | TNFSF10;FASLG;BID;FAS;BAK1;BAX;CASP3;CASP10;CASP9 | significant |
| KEGG_MEDICUS_REFERENCE_RECRUITMENT_AND_FORMATION_OF_THE_MCC | 0.0003001 | 0.0045308 | 0.4984931 | 0.7836042 | 2.1153401 | 9 | CDC20;TTK;NDC80;MAD2L1;BUB1;BUB1B | significant |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 0.0000614 | 0.0011880 | 0.5384341 | 0.4678373 | 2.1130272 | 56 | NDUFA13;COA6;COX6A2;NDUFA11;SDHD;UQCRFS1;NDUFS8;SDHB;COX8A;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;COX6B1;NDUFA12;NDUFC2;SDHA;COX5A;NDUFS2;NDUFA8;NDUFA6;SDHC;NDUFS7;COA3;NDUFB8;NDUFB7;NDUFB9;NDUFV2;COX4I1 | significant |
| KEGG_MEDICUS_REFERENCE_OKAZAKI_FRAGMENT_MATURATION | 0.0006656 | 0.0080784 | 0.4772708 | 0.7378247 | 2.1082137 | 11 | FEN1;RNASEH2B;POLD3;RNASEH2A;PCNA;DNA2;POLD1;RNASEH2C | significant |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 0.0006214 | 0.0077209 | 0.4772708 | 0.6599038 | 2.1040594 | 15 | MCM5;CDC45;MCM6;MCM2;MCM7;MCM3;MCM4;UBB;GINS2;VCP;GINS3;NPLOC4 | significant |
| KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY | 0.0000407 | 0.0008990 | 0.5573322 | 0.9085726 | 2.1027635 | 6 | CASP1;IL18;IL1B;NLRP3 | significant |
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 0.0002091 | 0.0032364 | 0.5188481 | 0.4891834 | 2.0841072 | 44 | IL2RB;IFNG;STAT1;IL15;IFNGR1;IL2RG;IL7;JAK2;IL15RA;IFNGR2;IFNAR2;PIM1;IL13RA1;IL2RA;IL12RB2;IL6R;IL7R;STAT5A | significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0003899 | 0.0056126 | 0.4984931 | 0.5447894 | 2.0789158 | 30 | ARPC1B;ACTR3;ARPC5L;ARPC5;CYTH1;ARPC2;ARPC4;BRK1;ACTB;ARPC1A;ACTR2;ACTG1;PIK3CG | significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE | 0.0000458 | 0.0009785 | 0.5573322 | 0.9428799 | 2.0699072 | 5 | C1QA;C1QB;C1QC;C1S;C1R | significant |
| KEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION | 0.0005606 | 0.0073831 | 0.4772708 | 0.8082640 | 2.0631901 | 8 | MCM5;MCM6;MCM2;POLD3;MCM7;MCM3;MCM4;PIF1 | significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 0.0016225 | 0.0173164 | 0.4550599 | 0.5735854 | 2.0439802 | 22 | TUBA4A;KIF2C;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;AURKA;TUBB6;MAPRE1;TUBA1B;TUBB3 | significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0008108 | 0.0094692 | 0.4772708 | 0.6267495 | 2.0262024 | 16 | NCF2;CYBB;RAC2;NCF4;NCF1;CYBA | significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0005290 | 0.0071179 | 0.4772708 | 0.4957839 | 2.0220983 | 38 | NDUFA13;NDUFA11;NDUFS8;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;NDUFA12;NDUFC2;NDUFS5;NDUFB5;NDUFB4;NDUFAB1;NDUFS2;NDUFA8;NDUFA6;NDUFS7;NDUFB8;NDUFA3;NDUFV3;NDUFB7;NDUFB9;NDUFV2 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0006237 | 0.0077209 | 0.4772708 | 0.4889744 | 2.0073485 | 39 | NDUFA13;NDUFA11;NDUFS8;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;NDUFA12;NDUFC2;NDUFS5;NDUFB5;NDUFB4;NDUFAB1;NDUFS2;NDUFA8;NDUFA6;NDUFS7;NDUFB8;NDUFA3;NDUFV3;NDUFB7;NDUFB9;NDUFV2 | significant |
| KEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT | 0.0009536 | 0.0105412 | 0.4772708 | 0.8298070 | 2.0054899 | 7 | CP;TFRC;STEAP3;SLC39A8 | significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 0.0017893 | 0.0184598 | 0.4550599 | 0.5240957 | 1.9780594 | 29 | NUP155;NDC1;ALYREF;NUP88;NXT2;NUP85;NUP210;NUP160;NUP37;NUP93;SEH1L;NUP54;NUP107;NUP62;NUP214;NCBP1;NUP35;NUP205;SRSF3 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0009519 | 0.0105412 | 0.4772708 | 0.4798902 | 1.9700558 | 39 | NDUFA13;NDUFA11;NDUFS8;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;NDUFA12;NDUFC2;NDUFS5;NDUFB5;NDUFB4;NDUFAB1;NDUFS2;NDUFA8;NDUFA6;NDUFS7;NDUFB8;NDUFA3;NDUFV3;NDUFB7;NDUFB9;NDUFV2 | significant |
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0029548 | 0.0280273 | 0.4317077 | 0.5421601 | 1.9697010 | 23 | IL21R;IL2RB;STAT1;IL15;IL2RG;IL7;IL15RA;IL2RA;IL7R;IL9R;STAT5A;JAK3;IL4R | significant |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 0.0061726 | 0.0471708 | 0.4070179 | 0.5804985 | 1.9326450 | 17 | RFC4;FEN1;POLD3;POLE3;RFC2;POLE2;RFC5;PCNA | significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 0.0035144 | 0.0315275 | 0.4317077 | 0.5392212 | 1.9215227 | 22 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;AURKA;TUBB6;TUBA1B;TUBB3;CKAP5 | significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 0.0022332 | 0.0219425 | 0.4317077 | 0.5198518 | 1.9182094 | 26 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TPX2;TUBB6;TUBGCP2;TUBA1B;TUBB3;CKAP5 | significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_INNER_KINETOCHORE | 0.0032278 | 0.0298212 | 0.4317077 | 0.6235506 | 1.9128538 | 14 | CENPW;CENPA;CENPQ;CENPM;CENPN;CENPO;CENPL | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0077307 | 0.0558407 | 0.4070179 | 0.5708339 | 1.9004687 | 17 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;TUBB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 0.0037292 | 0.0329769 | 0.4317077 | 0.6172700 | 1.8935869 | 14 | CD19;LYN;SYK;IFITM1;CD81;PIK3R3 | significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 0.0053998 | 0.0434091 | 0.4070179 | 0.5576298 | 1.8909212 | 19 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;CENPE;BUB1B;TUBA1B;TUBB3;CENPF | significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 0.0056439 | 0.0442225 | 0.4070179 | 0.5564101 | 1.8867850 | 19 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;KIF2A;PLK1;TUBA1B;TUBB3 | significant |
| KEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY | 0.0042306 | 0.0358732 | 0.4070179 | 0.6132959 | 1.8813959 | 14 | UBE2T;FANCE;ATR;TOPBP1;FANCI;FANCC;FANCA;UBB | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0021026 | 0.0209921 | 0.4317077 | 0.4578921 | 1.8797489 | 39 | NDUFA13;NDUFA11;NDUFS8;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;NDUFA12;NDUFC2;NDUFS5;NDUFB5;NDUFB4;NDUFAB1;NDUFS2;NDUFA8;NDUFA6;NDUFS7;NDUFB8;NDUFA3;NDUFV3;NDUFB7;NDUFB9;NDUFV2 | significant |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0040758 | 0.0350405 | 0.4070179 | 0.4949572 | 1.8680842 | 29 | NCF2;CYBB;RAC2;NCF4;CREB3L1;NCF1;CYBA;CREB3L2;CREB5;MAPK1;PRNP | significant |
| KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M | 0.0077582 | 0.0558407 | 0.4070179 | 0.6662876 | 1.8652797 | 10 | CDK1;CCNB2;CCNB1;CHEK1;CDC25B;CDC25C;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS | 0.0097682 | 0.0657228 | 0.3807304 | 0.6227000 | 1.8579845 | 12 | IDO1;TDO2;QPRT;KYNU;KMO | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.0102476 | 0.0674815 | 0.3807304 | 0.6204925 | 1.8513980 | 12 | CCR5;CXCR4;GNAI2;BAD | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0050505 | 0.0416833 | 0.4070179 | 0.5724906 | 1.8507903 | 16 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;TUBB3 | significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0059228 | 0.0458279 | 0.4070179 | 0.5349678 | 1.8430028 | 20 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;TUBB3 | significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 0.0074953 | 0.0552329 | 0.4070179 | 0.5715713 | 1.8224171 | 15 | CCNE1;CKS1B;E2F1;E2F3;SKP2;RBX1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M | 0.0121785 | 0.0769233 | 0.3807304 | 0.6472221 | 1.8119057 | 10 | CDK1;CCNB2;CCNB1;CHEK1;CDC25C;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.0051505 | 0.0419494 | 0.4070179 | 0.5162474 | 1.8063213 | 21 | CDC20;MAD2L1;PTTG2;PTTG1;CDC26;BUB1B;MAD2L2;ANAPC11;ANAPC10;CDC27 | significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.0064459 | 0.0480726 | 0.4070179 | 0.4879983 | 1.8006729 | 26 | PAK1;CFL1;CCR5;GNB4;RAC2;CXCR4;GNG10;GNGT2;GNB2 | significant |
| KEGG_MEDICUS_REFERENCE_MODIFYING_OF_CONDENSIN_II_SUBUNITS | 0.0085265 | 0.0593020 | 0.3807304 | 0.7719322 | 1.7865285 | 6 | CDK1;NCAPH2;PLK1;NCAPD3;AURKB | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0099117 | 0.0659711 | 0.3807304 | 0.6205444 | 1.7731045 | 11 | BID;FAS;BAK1;BAX;CASP3;APP;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 0.0079362 | 0.0564653 | 0.3807304 | 0.4789568 | 1.7673104 | 26 | RFC4;POLD3;POLE3;MSH2;RFC2;POLE2;RFC5;EXO1;RPA2;MSH6;PCNA | non-significant |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 0.0055784 | 0.0442225 | 0.4070179 | 0.4510056 | 1.7644455 | 33 | ARPC1B;ACTR3;CLDN7;ARPC5L;ARPC5;ARPC2;ARPC4;CLDN10;ACTB;ARPC1A;ACTR2;ACTG1 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0040186 | 0.0350352 | 0.4070179 | 0.4140900 | 1.7641805 | 44 | NDUFA13;NDUFA11;NDUFS8;NDUFS3;NDUFV1;NDUFB11;NDUFS1;NDUFA9;NDUFA12;NDUFC2;NDUFS5;CAPN2;NDUFB5;NDUFB4;NDUFAB1;APP;CAPN1;NDUFS2;NDUFA8;NDUFA6;NDUFS7;NDUFB8;NDUFA3;NDUFV3;NDUFB7;NDUFB9;NDUFV2 | significant |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 0.0114003 | 0.0735080 | 0.3807304 | 0.5101826 | 1.7576160 | 20 | TLR1;TLR2;TNF;IKBKG;IRAK1;MAP3K7;MYD88;NFKB1;TAB2;TLR4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MEVALONATE_PATHWAY | 0.0191510 | 0.1077682 | 0.3524879 | 0.5809113 | 1.7332974 | 12 | FDPS;ACAT2;IDI1;MVD;HMGCS1;PMVK;MVK;HMGCR | non-significant |
| KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M | 0.0162149 | 0.0955907 | 0.3524879 | 0.7156822 | 1.7296713 | 7 | CDK1;CCNB2;CCNB1;CHEK1;WEE1;ATR | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00264 | 0.0151497 | 0.0910454 | 0.3807304 | 0.6028580 | 1.7225685 | 11 | CCNE1;CCNA2;E2F1;E2F3;SKP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_SECOND_CARBON_OXIDATION_2 | 0.0231047 | 0.1254547 | 0.3524879 | 0.6140359 | 1.7190005 | 10 | FH;SDHD;SDHB;MDH1;SDHA;SUCLG1;SDHC | non-significant |
| KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY | 0.0145976 | 0.0894642 | 0.3807304 | 0.6733830 | 1.7188904 | 8 | FCGR3A;FCGR3B;RAC2;FCGR2A | non-significant |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 0.0093613 | 0.0636775 | 0.3807304 | 0.4457704 | 1.7168249 | 31 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TPX2;TUBB6;HAUS8;TUBGCP2;TUBA1B;TUBB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH | 0.0173474 | 0.0994263 | 0.3524879 | 0.7407697 | 1.7144074 | 6 | PLAU;C1S;SERPING1;C1R | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00482 | 0.0175473 | 0.0996491 | 0.3524879 | 0.6318297 | 1.7056247 | 9 | CCNE1;CCNA2;E2F1;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 0.0321972 | 0.1594403 | 0.3217759 | 0.5095753 | 1.6965213 | 17 | CDC20;MAD2L1;CDC26;BUB1B;ANAPC11;ANAPC10;CDC27;TRIP13 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 0.0173432 | 0.0994263 | 0.3524879 | 0.5252381 | 1.6746866 | 15 | CDK1;CDCA5;PLK1;PPP2R5B;PPP2CB;STAG1;PPP2R1A | non-significant |
| KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 0.0235870 | 0.1269594 | 0.3524879 | 0.6174729 | 1.6668686 | 9 | PDCD1;CD274;PTPN6;PIK3R3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY | 0.0259031 | 0.1347397 | 0.3524879 | 0.5580329 | 1.6650340 | 12 | CCL2;BIRC3;IKBKG;BIRC2;NFKB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 0.0119491 | 0.0762524 | 0.3807304 | 0.4362177 | 1.6646063 | 30 | CCL4;CCL3;CCL2;GNB4;GNG10;GNGT2;GNB2;PIK3CG | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0238411 | 0.1272212 | 0.3524879 | 0.6885976 | 1.6642127 | 7 | IL2RB;IL2RG;STAT5A;JAK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.0173140 | 0.0994263 | 0.3524879 | 0.4509901 | 1.6641157 | 26 | PAK1;CFL1;GNB4;RAC2;CXCR4;GNG10;GNGT2;GNB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00536 | 0.0218298 | 0.1206486 | 0.3524879 | 0.5820829 | 1.6632071 | 11 | CDKN2A;CCNE1;E2F1;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_P27_CELL_CYCLE_G1_S | 0.0216472 | 0.1206486 | 0.3524879 | 0.5406187 | 1.6584455 | 14 | CCNE1;CCNA2;E2F1;E2F3;SKP2;RBX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 0.0244322 | 0.1292611 | 0.3524879 | 0.4808951 | 1.6567185 | 20 | NCAPH2;NCAPG;TOP2A;SMC4;KIF4A;PPP2R5B;SMC2;PPP2CB;NCAPD3;PPP2R1A | non-significant |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 0.0127951 | 0.0792017 | 0.3807304 | 0.4700483 | 1.6446733 | 21 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;MAPRE1;TUBA1B;TUBB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION | 0.0258333 | 0.1347397 | 0.3524879 | 0.6083910 | 1.6423518 | 9 | IDH2;IDH1;IDH3G | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0298714 | 0.1515608 | 0.3524879 | 0.4889744 | 1.6250443 | 18 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 0.0303735 | 0.1528551 | 0.3524879 | 0.4873708 | 1.6197148 | 18 | GSTA5;GSTP1;GSTA2;GSTA1;GSTO1;MGST1;MGST3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 0.0290477 | 0.1485993 | 0.3524879 | 0.4507153 | 1.6061307 | 22 | GSTA5;GSTP1;GSTA2;GSTA1;GSTO1;MGST1;MGST3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.0285797 | 0.1474234 | 0.3524879 | 0.4963146 | 1.6045228 | 16 | CDC20;PTTG2;PTTG1;CDC26;ANAPC11;ANAPC10;CDC27 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_GLC_6P_TO_MAN_P_DOL | 0.0352678 | 0.1705530 | 0.3217759 | 0.5942013 | 1.6040468 | 9 | DPM1;GMPPB;PMM1;GPI | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0328836 | 0.1615473 | 0.3217759 | 0.4824993 | 1.6035250 | 18 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;TUBB3;GSK3B | non-significant |
| KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY | 0.0547134 | 0.2342368 | 0.3217759 | 0.5712500 | 1.5992209 | 10 | PAK1;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;CDC42;RAC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.0365269 | 0.1752727 | 0.3217759 | 0.6594434 | 1.5937525 | 7 | STAT1;EGFR;STAT5A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0316182 | 0.1578360 | 0.3217759 | 0.4461717 | 1.5899396 | 22 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;TUBB3;CAPN2;APP;CAPN1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.0387456 | 0.1844887 | 0.3217759 | 0.6170229 | 1.5750245 | 8 | EGFR;BAD;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M | 0.0411083 | 0.1913235 | 0.3217759 | 0.5828170 | 1.5733149 | 9 | CDK1;CCNB2;CCNB1;CHEK1;ATR | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY | 0.0476903 | 0.2147644 | 0.3217759 | 0.5268972 | 1.5721325 | 12 | FOS;JUN;MAP2K2;MAPK1;PRKCB;RAF1;MAP2K1;ARAF | non-significant |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 0.0476971 | 0.2147644 | 0.3217759 | 0.4323442 | 1.5707331 | 23 | GSTA5;GSTP1;GSTA2;GSTA1;GSTO1;MGST1;MGST3 | non-significant |
| KEGG_MEDICUS_REFERENCE_II_BLOOD_GROUP_ANTIGEN_BIOSYNTHESIS | 0.0409014 | 0.1913235 | 0.3217759 | 0.6497949 | 1.5704338 | 7 | B3GNT3;B3GNT2;B4GALT4;B4GALT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE | 0.0391935 | 0.1851969 | 0.3217759 | 0.6147331 | 1.5691796 | 8 | PPP1CA;PPP1CB;PPP1CC;RAF1;MRAS;ARAF | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCNE_TO_CELL_CYCLE_G1_S | 0.0706215 | 0.2875966 | 0.2878571 | 0.6720627 | 1.5553945 | 6 | CCNE1;E2F1;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00498 | 0.0427769 | 0.1961400 | 0.3217759 | 0.6089759 | 1.5544837 | 8 | CCNE1;E2F1;E2F3;CDKN1A;CCNE2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_P27_CELL_CYCLE_G1_S | 0.0730994 | 0.2914313 | 0.2878571 | 0.6393334 | 1.5451503 | 7 | CCNE1;E2F1;E2F3;CCNE2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.0559544 | 0.2356176 | 0.3217759 | 0.5177897 | 1.5449581 | 12 | CXCR4;GNAI2;BAD;AKT1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_II | 0.0734463 | 0.2914313 | 0.2820134 | 0.6606827 | 1.5290573 | 6 | GSTO1;SDHD;SDHB;SDHA;SDHC | non-significant |
| KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY | 0.0760234 | 0.2978385 | 0.2820134 | 0.6196404 | 1.4975560 | 7 | MAP3K5;FASLG;FAS;DAXX | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.0808383 | 0.3091414 | 0.2765006 | 0.5856965 | 1.4950601 | 8 | EGFR;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0898204 | 0.3232489 | 0.2616635 | 0.5828620 | 1.4878248 | 8 | BID;BAK1;BAX;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0898204 | 0.3232489 | 0.2616635 | 0.5818709 | 1.4852948 | 8 | LYN;SYK;BLNK;PLCG2;BTK;ITPR3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_REL_TO_TRANSCRIPTION | 0.0898204 | 0.3232489 | 0.2616635 | 0.5812865 | 1.4838030 | 8 | BIRC3;CD40;BCL2A1;TRAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0898204 | 0.3232489 | 0.2616635 | 0.5804173 | 1.4815844 | 8 | VCAM1;CYBB;MMP9;MMP2;NFKB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.0589274 | 0.2464598 | 0.3217759 | 0.4011019 | 1.4800323 | 26 | TLR2;FOS;IRAK1;JUN;MAP2K2;MAP3K7;MAPK1;MYD88;MAP2K1;MAPK13;TAB2;TLR4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0544447 | 0.2342368 | 0.3217759 | 0.4560225 | 1.4742634 | 16 | IFNG;STAT1;IFNGR1;JAK2;IFNGR2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY | 0.1033333 | 0.3573371 | 0.2572065 | 0.4811344 | 1.4667034 | 13 | YWHAH;YWHAQ;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.0809061 | 0.3091414 | 0.2878571 | 0.4366844 | 1.4538469 | 17 | LYN;SYK;BLNK;PLCG2;BTK;CALM3;PPP3CA;CALM2;NFATC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 0.0843405 | 0.3183341 | 0.2878051 | 0.3988082 | 1.4488946 | 23 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6 | non-significant |
| KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.1009174 | 0.3515191 | 0.2489111 | 0.5118155 | 1.4328334 | 10 | EGFR;RPS6KB2;AKT1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.0777476 | 0.3007860 | 0.2878051 | 0.3886598 | 1.4194882 | 24 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;TUBA1B;PLEKHM2;TUBB3 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_CDKN1B_TO_P27_CELL_CYCLE_G1_S | 0.1167665 | 0.3784212 | 0.2279872 | 0.5553949 | 1.4177118 | 8 | CCNE1;E2F1;E2F3;CCNE2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.0720530 | 0.2914313 | 0.2878051 | 0.3704406 | 1.4136009 | 30 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6;SNAPIN;TUBA1B;PLEKHM2;TUBB3;BLOC1S2;KXD1;ARL8B | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR2_TO_CELL_SURFACE_MOLECULE_ENDOCYTOSIS | 0.1101695 | 0.3717525 | 0.2279872 | 0.6040413 | 1.3979686 | 6 | ICAM1;IFNGR1;MICA;MICB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00497 | 0.1231231 | 0.3868691 | 0.2220560 | 0.5161558 | 1.3933629 | 9 | CCNE1;E2F1;E2F3;CDKN1A;CCNE2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0890749 | 0.3232489 | 0.2878051 | 0.3800273 | 1.3879600 | 24 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 0.1067961 | 0.3672600 | 0.2489111 | 0.4168725 | 1.3878873 | 17 | IL1B;ZFP36;IRAK1;MAP3K7;MYD88;IL1RAP;TAB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 0.0702034 | 0.2875966 | 0.2878051 | 0.3305362 | 1.3861082 | 41 | TUBA4A;TUBA3C;TUBB;RILP;TUBA1A;TUBA3D;TUBA1C;TUBB6;DYNLT1;DYNLL2;TUBA1B;TUBB3;DYNLL1;ACTR1A;DCTN3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 0.0839826 | 0.3183341 | 0.2878051 | 0.3484267 | 1.3847816 | 34 | FAU;RPS10;RPS21;RPS3;RPS19;RPS16;RPSA;RPS7;RPS12;RPS11;RPS27A;RPS27;RPS13;RPS17;RPS18;RPS5;RPS25;RPS3A;RPS28 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 0.1165049 | 0.3784212 | 0.2377938 | 0.4066018 | 1.3536932 | 17 | TNF;IKBKG;IRAK1;MAP3K7;MYD88;NFKB1;TAB2;IL6;NFKBIA;CHUK;TLR5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS | 0.1467890 | 0.4432311 | 0.2042948 | 0.4832997 | 1.3530030 | 10 | AKR1C3;SRD5A1;SRD5A3;HSD17B2;HSD17B6 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.1461988 | 0.4432311 | 0.1999152 | 0.5550710 | 1.3415039 | 7 | STAT1;EGFR;STAT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 0.1495017 | 0.4466089 | 0.2114002 | 0.4091312 | 1.3226700 | 16 | CDC20;PTTG1;CDC26;ANAPC11;ANAPC10;CDC27 | non-significant |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 0.1208791 | 0.3856916 | 0.2489111 | 0.3582433 | 1.3218876 | 26 | IFNG;STAT1;IFNGR1;JAK2;IFNGR2;IFNAR2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1010830 | 0.3515191 | 0.2712886 | 0.3625481 | 1.3186606 | 25 | TUBA4A;TUBA3C;TUBB;TUBA1A;TUBA3D;TUBA1C;TUBB6 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOD_NFKB_SIGNALING_PATHWAY | 0.1531532 | 0.4471783 | 0.1978220 | 0.4868000 | 1.3141170 | 9 | RIPK2;IKBKG;NFKB1;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 0.1531532 | 0.4471783 | 0.1978220 | 0.4850698 | 1.3094462 | 9 | EGFR;BAD;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 0.1178707 | 0.3794842 | 0.2572065 | 0.3358578 | 1.3076289 | 32 | RAD51C;RFC4;POLD3;POLE3;BARD1;RFC2;POLE2;RFC5;RPA2;PCNA;RAD54L | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.1143911 | 0.3769735 | 0.2572065 | 0.3393021 | 1.3067764 | 31 | CCL2;GNB4;CCR2;GNG10;IKBKG;GNGT2;GNB2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY | 0.1553398 | 0.4514335 | 0.2042948 | 0.4361744 | 1.3014377 | 12 | FOS;JUN;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 0.1634615 | 0.4641408 | 0.1978220 | 0.4532888 | 1.2951990 | 11 | GNAI2;BAD;ADRB2;AKT1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 0.1773700 | 0.4851952 | 0.1847065 | 0.4619184 | 1.2931459 | 10 | BIRC5;NFKB1;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.1632653 | 0.4641408 | 0.2042948 | 0.4024839 | 1.2832931 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 0.1602787 | 0.4614537 | 0.2089550 | 0.3516135 | 1.2774334 | 23 | PFKP;ENO1;PKM;LDHA;PFKL;BPGM;GAPDH;PGAM1;LDHB | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 0.1741742 | 0.4826474 | 0.1847065 | 0.4697369 | 1.2680551 | 9 | EGFR;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.1802721 | 0.4894230 | 0.1938133 | 0.4127299 | 1.2661234 | 14 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 0.1771772 | 0.4851952 | 0.1830239 | 0.4685284 | 1.2647927 | 9 | ICOS;PIK3R3;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 0.1746575 | 0.4826474 | 0.1978220 | 0.3456162 | 1.2622816 | 24 | TNF;RPS6KA4;CREB3L1;CREB3L2;CREB5;MAP3K7;TRADD | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST | 0.1987179 | 0.5134452 | 0.1782199 | 0.4374276 | 1.2498781 | 11 | RPN1;ALG6;DDOST;ALG8;RPN2;STT3A;STT3B | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 0.1904762 | 0.4995964 | 0.1882041 | 0.3905413 | 1.2452148 | 15 | EGFR;GRB2;BAD | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_TP53_TO_TRANSCRIPTION | 0.1861862 | 0.4989145 | 0.1782199 | 0.4597539 | 1.2411060 | 9 | GADD45A;BAK1;DDB2;BAX | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_E2_TO_NOD_NFKB_SIGNALING_PATHWAY | 0.1891892 | 0.4995964 | 0.1766943 | 0.4576732 | 1.2354891 | 9 | RIPK2;IKBKG;NFKB1;CDC42;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY | 0.2147436 | 0.5447798 | 0.1709323 | 0.4316429 | 1.2333493 | 11 | IKBKG;MAP3K7;TRADD;NFKB1;TAB2;NFKBIA;CHUK;TAB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.2147436 | 0.5447798 | 0.1709323 | 0.4316324 | 1.2333193 | 11 | EGFR;RPS6KB2;AKT1 | non-significant |
| KEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION | 0.2307692 | 0.5736793 | 0.1644058 | 0.4265266 | 1.2187302 | 11 | GZMB;HDAC2;SIN3A;HDAC1;CSF2;ELANE;MPO;RUNX1;NCOR1;DEFA3;IL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 0.2119205 | 0.5420612 | 0.1752040 | 0.3589172 | 1.2170871 | 19 | IL1B;FOS;IRAK1;JUN;MAP3K7;MYD88;IL1RAP | non-significant |
| KEGG_MEDICUS_VARIANT_EREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.2354740 | 0.5807108 | 0.1585141 | 0.4327006 | 1.2113504 | 10 | EGFR;RPS6KB2;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY | 0.2335329 | 0.5782275 | 0.1574029 | 0.4743708 | 1.2108880 | 8 | EGFR;PLCG2;PRKCB | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 0.2197802 | 0.5530242 | 0.1813831 | 0.3274942 | 1.2084262 | 26 | CCL5;CCR5;GNB4;GNG10;GNGT2;GNB2;GNG5;PRKCB | non-significant |
| KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.2395210 | 0.5825107 | 0.1552420 | 0.4709269 | 1.2020970 | 8 | EGFR;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2459547 | 0.5878222 | 0.1596467 | 0.3609337 | 1.2016510 | 17 | GSTO1;COX6A2;COX7A2;COX8A;COX6B1;COX7A2L;COX5A;COX5B;COX4I1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY | 0.2455090 | 0.5878222 | 0.1531588 | 0.4677716 | 1.1940427 | 8 | MAP3K5;FOS;JUN | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 0.2538226 | 0.5981370 | 0.1521449 | 0.4255004 | 1.1911931 | 10 | BAD;AKT1;PIK3CB;MET;PIK3CD;AKT3;PIK3CA;HGF;GAB1;AKT2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY | 0.2282282 | 0.5696503 | 0.1596467 | 0.4409486 | 1.1903410 | 9 | BIRC5;E2F1;RAF1;SRC | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.2380952 | 0.5825107 | 0.1669338 | 0.3725398 | 1.1878183 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 0.1899441 | 0.4995964 | 0.2450418 | 0.2454585 | 1.1758539 | 81 | UBA52;RPL18A;RPL35A;FAU;RPL15;RPS10;RPL35;RPS21;RPS3;RPL17;RPS19;RPS16;RPSA;RPS7;RPL4;RPL24;RPS12;RPS11;RPS27A;RPL27;RPL32;RPS27;RPL7;RPS13;RPS17;RPL10;RPL39;RPS18;RPS5;RPL21;RPL12;RPL10A;RPLP0;RPS25;RPS3A;RPS28;RPL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 0.2404181 | 0.5825107 | 0.1682382 | 0.3235963 | 1.1756453 | 23 | KDELR3;TMED1;COPB2;COPE;TMED9;COPB1;TMED3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.2551020 | 0.5981370 | 0.1608014 | 0.3651715 | 1.1643249 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY | 0.2631579 | 0.6018075 | 0.1455161 | 0.4800677 | 1.1602347 | 7 | CD40;RELB;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_PI3K_SIGNALING_PATHWAY | 0.2966361 | 0.6266817 | 0.1395997 | 0.4136397 | 1.1579891 | 10 | GNAI2;ADRB2;AKT1;PIK3CB;PIK3CD;AKT3;PIK3CA;GNAI3;AKT2;GNAI1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.2631579 | 0.6018075 | 0.1455161 | 0.4789054 | 1.1574255 | 7 | FKBP8;CISD1;CISD2;OPTN;HK1;FAF2;PINK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.2566038 | 0.5990373 | 0.1695706 | 0.3028597 | 1.1557123 | 30 | ACTN1;ITGB7;VCL;ACTB;ACTG1;ITGB1;FN1;ILK;ITGB8;ITGA9;ITGB5;ITGA4;ITGA5;ITGB4;ACTN4;ITGA1;ITGAV;ITGA10 | non-significant |
| KEGG_MEDICUS_VARIANT_TMPRSS2_ERG_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.2631579 | 0.6018075 | 0.1455161 | 0.4771974 | 1.1532978 | 7 | MMP3;PLAU;MMP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY | 0.2933333 | 0.6234891 | 0.1301056 | 0.5247409 | 1.1519653 | 5 | E2F1;RAF1;SRC;ARRB1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.2672673 | 0.6029221 | 0.1464162 | 0.4254761 | 1.1485730 | 9 | AKT1;PIK3CB;MET;MTOR;PIK3CD;AKT3;PIK3CA;GAB1;AKT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.2672673 | 0.6029221 | 0.1464162 | 0.4254761 | 1.1485730 | 9 | BAD;AKT1;PIK3CB;MET;PIK3CD;AKT3;PIK3CA;GAB1;AKT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 0.2583893 | 0.5990373 | 0.1585141 | 0.3455341 | 1.1483384 | 18 | CCT6A;CCT7;CCT4;CCT3;NOP10;RUVBL2;TCP1;DKC1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2524917 | 0.5981370 | 0.1596467 | 0.3549923 | 1.1476456 | 16 | COX6A2;COX7A2;COX8A;COX6B1;COX7A2L;COX5A;APP;COX5B;COX4I1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY | 0.2884615 | 0.6234891 | 0.1455161 | 0.3992667 | 1.1408396 | 11 | EGFR;GRB2;NRAS;RASSF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2678571 | 0.6029221 | 0.1608014 | 0.3037639 | 1.1406772 | 27 | IL27RA;STAT1;OSM;JAK2;OSMR;IL13RA1;IL6R | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.2634731 | 0.6018075 | 0.1473312 | 0.4467900 | 1.1404847 | 8 | EGFR;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S | 0.3058104 | 0.6373624 | 0.1372508 | 0.4060902 | 1.1368541 | 10 | CDKN2A;E2F1;E2F3;CDK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX | 0.2814371 | 0.6177645 | 0.1420566 | 0.4430295 | 1.1308857 | 8 | SMC6;RAD18;RNF168;UBB;NSMCE4A | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.2792793 | 0.6152095 | 0.1429011 | 0.4180127 | 1.1284256 | 9 | VCL;ACTB;ACTG1;ITGB1;ITGA5 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2925170 | 0.6234891 | 0.1492075 | 0.3535353 | 1.1272237 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 0.3106796 | 0.6424574 | 0.1404062 | 0.3352148 | 1.1160257 | 17 | CCR5;CXCR4;PLCG2;CALM3;PPP3CA;CALM2;NFATC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_LIGHT_HVEM_NFKB_SIGNALING_PATHWAY | 0.3211009 | 0.6558174 | 0.1335550 | 0.3982128 | 1.1148013 | 10 | TNFSF14;IKBKG;NFKB1;TNFRSF14;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY | 0.3241590 | 0.6578834 | 0.1328463 | 0.3971583 | 1.1118492 | 10 | IKBKG;MAP3K7;NFKB1;TICAM1;TLR3;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_PKR_EIF2ALPHA_SIGNALING_PATHWAY | 0.3099415 | 0.6424574 | 0.1328463 | 0.4584379 | 1.1079594 | 7 | EIF2B3;EIF2S1;EIF2B5;EIF2B4;EIF2B1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.3401361 | 0.6748212 | 0.1372508 | 0.3432069 | 1.0942925 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 0.3300971 | 0.6641133 | 0.1357409 | 0.3277284 | 1.0911012 | 17 | TNF;MAP2K2;MAPK1;APP;RAF1;MAP2K1;NFKB1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 0.3401361 | 0.6748212 | 0.1372508 | 0.3421713 | 1.0909905 | 15 | GRB2;MAP2K2;MAPK1;RAF1;SRC;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 0.3113772 | 0.6424574 | 0.1342735 | 0.4254519 | 1.0860166 | 8 | AKT1;PIK3CB;PDGFRA;MTOR;PIK3CD;AKT3;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.3493590 | 0.6821868 | 0.1307771 | 0.3798765 | 1.0854351 | 11 | EGFR;RPS6KB2;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_INTRINSIC_APOPTOTIC_PATHWAY | 0.3566667 | 0.6877778 | 0.1321473 | 0.3555333 | 1.0838175 | 13 | PMAIP1;BAD;BAK1;BAX;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION | 0.3600000 | 0.6886217 | 0.1157344 | 0.4932149 | 1.0827561 | 5 | HEXA;HEXB;GLB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P53_MEDIATED_TRANSCRIPTION | 0.3608563 | 0.6886217 | 0.1250334 | 0.3862339 | 1.0812661 | 10 | GADD45A;BAK1;DDB2;BAX | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS | 0.3531073 | 0.6834019 | 0.1209851 | 0.4661826 | 1.0789141 | 6 | UGP2;GYG1;GBE1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ANXA2_S100A10_REGULATED_ACTIN_CYTOSKELETON | 0.3626667 | 0.6886217 | 0.1152400 | 0.4901655 | 1.0760617 | 5 | ACTB;ACTG1;ANXA2;S100A10 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 0.3455150 | 0.6790717 | 0.1342735 | 0.3325988 | 1.0752501 | 16 | TNF;FOS;JUN;MAP3K7;TRADD | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2 | 0.3626667 | 0.6886217 | 0.1152400 | 0.4872306 | 1.0696189 | 5 | NRBF2;PIK3C3;BECN1;PIK3R4;UVRAG | non-significant |
| KEGG_MEDICUS_VARIANT_AREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.3822630 | 0.7146174 | 0.1209851 | 0.3807502 | 1.0659146 | 10 | EGFR;RPS6KB2;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY | 0.3653846 | 0.6902241 | 0.1275053 | 0.3704117 | 1.0583910 | 11 | EGFR;GRB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.4013605 | 0.7262250 | 0.1250334 | 0.3311922 | 1.0559842 | 15 | COX6A2;COX7A2;COX8A;COX6B1;COX7A2L;COX5A;COX5B;COX4I1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.4217687 | 0.7367644 | 0.1215433 | 0.3418200 | 1.0485944 | 14 | EGFR;IKBKG;NFKB1;AKT1;NFKBIA;PIK3CB;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY | 0.3975535 | 0.7262250 | 0.1182875 | 0.3721808 | 1.0419245 | 10 | TNF;CASP3;TRADD;FADD | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 0.4047619 | 0.7262250 | 0.1244342 | 0.3016356 | 1.0391566 | 20 | PTPN7;DUSP1;DUSP4;DUSP10;DUSP2;MAPK1;DUSP6 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.3532934 | 0.6834019 | 0.1250334 | 0.4066366 | 1.0379885 | 8 | BAD;AKT1;PIK3CB;PIK3CD;AKT3;PIK3CA;AKT2;ALK | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.4319728 | 0.7370440 | 0.1198878 | 0.3383407 | 1.0379212 | 14 | EGFR;PLCG2;MAP2K2;MAPK1;PRKCB;RAF1;MAP2K1;ARAF | non-significant |
| KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY | 0.4006116 | 0.7262250 | 0.1177658 | 0.3700747 | 1.0360283 | 10 | MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 0.3851133 | 0.7146174 | 0.1244342 | 0.3102681 | 1.0329710 | 17 | DDB2;RBX1;GTF2H1;CETN2;CDK7;ERCC2;RAD23A;GTF2H4;DDB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 0.3976608 | 0.7262250 | 0.1152400 | 0.4254276 | 1.0281797 | 7 | RPS6KB2;AKT1;MTOR;AKT3;PIK3CA;RPS6KB1;AKT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S | 0.4350282 | 0.7370440 | 0.1071402 | 0.4427388 | 1.0246567 | 6 | E2F1;E2F3;CDK4 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM | 0.4373089 | 0.7370440 | 0.1119183 | 0.3640128 | 1.0190581 | 10 | AKR1C3;AKR1A1;EPHX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 0.4234234 | 0.7367644 | 0.1128434 | 0.3756415 | 1.0140444 | 9 | CXCR4;RHOA;GNA13;ARHGEF1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY | 0.3922156 | 0.7247207 | 0.1177658 | 0.3956274 | 1.0098860 | 8 | AKR1C3;AKR1A1;HMOX1;KEAP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.4354354 | 0.7370440 | 0.1110115 | 0.3731801 | 1.0073999 | 9 | UQCRFS1;UQCRC1;UQCRH;UQCR10;CYC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066 | 0.4400000 | 0.7370440 | 0.1172497 | 0.3297344 | 1.0051715 | 13 | CDKN2A;E2F1;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.4661017 | 0.7612584 | 0.1028218 | 0.4333846 | 1.0030078 | 6 | MAP2K2;MAP2K1;MAP2K6;MAP2K3;MAP2K4 | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP | 0.4384384 | 0.7370440 | 0.1105647 | 0.3714092 | 1.0026194 | 9 | PNP;HPRT1;LACC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 0.4451827 | 0.7387885 | 0.1162341 | 0.3100815 | 1.0024545 | 16 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.4689266 | 0.7618518 | 0.1024494 | 0.4322845 | 1.0004616 | 6 | FUT3;FUT7;ST3GAL6;FUT4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_K15_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.4221557 | 0.7367644 | 0.1128434 | 0.3893639 | 0.9938977 | 8 | IKBKG;MAP3K7;NFKB1;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY | 0.4385965 | 0.7370440 | 0.1088201 | 0.4112238 | 0.9938516 | 7 | RAC2;SRC;RHOA;ITGAV;RAC1;RAC3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 0.4375000 | 0.7370440 | 0.1287887 | 0.2529912 | 0.9897644 | 33 | GNB4;CREB3L1;GNG10;CREB3L2;GNGT2;CREB5;GNB2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4829932 | 0.7663109 | 0.1123785 | 0.3102327 | 0.9891562 | 15 | GRB2;MAP2K2;MAPK1;RAF1;SRC;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_CELL_CYCLE_G1_S | 0.4745763 | 0.7658240 | 0.1017139 | 0.4260264 | 0.9859782 | 6 | E2F1;E2F3;RBL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 0.4774011 | 0.7663109 | 0.1013507 | 0.4254033 | 0.9845362 | 6 | AKT1;PIK3CB;PIK3CD;AKT3;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 0.4750831 | 0.7658240 | 0.1119183 | 0.3029887 | 0.9795245 | 16 | TNF;MAP2K2;MAPK1;RAF1;MAP2K1;NFKB1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY | 0.4733333 | 0.7658240 | 0.1123785 | 0.3209031 | 0.9782499 | 13 | EGFR;GRB2 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.4789644 | 0.7663109 | 0.1096841 | 0.3272059 | 0.9763024 | 12 | EGFR;RPS6KB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_UREA_CYCLE | 0.4887006 | 0.7677808 | 0.0999277 | 0.4187592 | 0.9691593 | 6 | ASS1;ARG2;ASL | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA1_TO_P53_MEDIATED_TRANSCRIPTION | 0.4862385 | 0.7663109 | 0.1051251 | 0.3460126 | 0.9686663 | 10 | GADD45A;BAK1;DDB2;BAX | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.4862385 | 0.7663109 | 0.1051251 | 0.3457744 | 0.9679994 | 10 | SQSTM1;FKBP8;CISD1;CISD2 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION | 0.4943503 | 0.7745245 | 0.0992333 | 0.4176501 | 0.9665924 | 6 | IKBKG;SHARPIN;TNFRSF1A;RIPK1;RNF31;RBCK1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5102041 | 0.7793801 | 0.1088201 | 0.3141605 | 0.9637439 | 14 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_HEME_BIOSYNTHESIS | 0.4954955 | 0.7745245 | 0.1028218 | 0.3563690 | 0.9620184 | 9 | HMBS;ALAS1;UROS;PPOX;UROD | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.4821429 | 0.7663109 | 0.1157344 | 0.2561497 | 0.9618791 | 27 | POMC;GNAI2;CREB3L1;ADCY7;ADCY3;CREB3L2;CREB5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 0.5016611 | 0.7770996 | 0.1083943 | 0.2973628 | 0.9613368 | 16 | TNF;IKBKG;MAP3K7;TRADD;NFKB1;TAB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 0.5136054 | 0.7793801 | 0.1083943 | 0.3010903 | 0.9600063 | 15 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;FLT3LG;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5170068 | 0.7805542 | 0.1079724 | 0.3127578 | 0.9594409 | 14 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS | 0.5000000 | 0.7770996 | 0.0985500 | 0.4098878 | 0.9486276 | 6 | B3GNT5;B4GALT4;B4GALT3;B4GALT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 0.5496689 | 0.7966696 | 0.1024494 | 0.2779620 | 0.9425685 | 19 | CXCR4;PLCG2;MAP2K2;MAPK1;PRKCB;RAF1;MAP2K1;ARAF | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 0.5646259 | 0.8082962 | 0.1024494 | 0.2943904 | 0.9386441 | 15 | EGFR;PLCG2;MAP2K2;MAPK1;PRKCB;RAF1;MAP2K1;ARAF | non-significant |
| KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.5306667 | 0.7858437 | 0.0916795 | 0.4261169 | 0.9354558 | 5 | FUT3;FUT4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 0.5719557 | 0.8101615 | 0.1067299 | 0.2426371 | 0.9344843 | 31 | GNB4;FOS;GNG10;GNGT2;GNB2;JUN;MAP2K2;MAPK1;GNG5;RAF1;MAP2K1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 0.5793358 | 0.8150201 | 0.1059203 | 0.2482181 | 0.9329694 | 28 | RHOG;ITGB7;RAC2;ITGB1;FN1;ITGB8;ITGA9;ITGB5;ITGA4;ITGA5;ITGB4;ITGA1;ITGAV;ITGA10;RAC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION | 0.5141243 | 0.7793801 | 0.0968878 | 0.4030494 | 0.9328011 | 6 | CDCA5;STAG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_VALINE_DEGRADATION | 0.5149701 | 0.7793801 | 0.1002791 | 0.3649011 | 0.9314535 | 8 | ACADM;HIBCH;ECHS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 0.5680272 | 0.8082962 | 0.1020801 | 0.2691468 | 0.9272301 | 20 | CREB3L1;CREB3L2;CREB5;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY | 0.5345345 | 0.7896823 | 0.0982123 | 0.3420145 | 0.9232685 | 9 | MYL9;MYL12A;MYL12B | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 0.5884354 | 0.8259444 | 0.0999277 | 0.2892200 | 0.9221586 | 15 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.5466667 | 0.7962039 | 0.0899861 | 0.4192998 | 0.9204902 | 5 | BAX;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE | 0.5259939 | 0.7853821 | 0.1002791 | 0.3275660 | 0.9170247 | 10 | TFEB;CALM3;PPP3CA;CALM2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.5367232 | 0.7899898 | 0.0943564 | 0.3952454 | 0.9147400 | 6 | MAPK1;MAPK13;MAPK11 | non-significant |
| KEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING | 0.5480226 | 0.7963051 | 0.0931455 | 0.3924052 | 0.9081666 | 6 | RPS6KA3;MAPK1;RPS6KA1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.5535168 | 0.7986641 | 0.0972151 | 0.3214818 | 0.8999918 | 10 | MYL9;MYL12A;MYL12B | non-significant |
| KEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM | 0.5680000 | 0.8082962 | 0.0878313 | 0.4091938 | 0.8983044 | 5 | MAOB;DDC;MAOA;TPH1;TPH2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.5760000 | 0.8140274 | 0.0870516 | 0.4070153 | 0.8935220 | 5 | FOS;JUN | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6156463 | 0.8375003 | 0.0972151 | 0.2878765 | 0.8831132 | 14 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR4_IRF3_7_SIGNALING_PATHWAY | 0.6167665 | 0.8375003 | 0.0897105 | 0.3410685 | 0.8706179 | 8 | IRF3;TICAM1;IRF7;TLR4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY | 0.6101695 | 0.8340381 | 0.0870516 | 0.3728159 | 0.8628301 | 6 | MAP3K5;DAXX;PARK7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.6377246 | 0.8489280 | 0.0878313 | 0.3371185 | 0.8605352 | 8 | BAK1;BAX;SOD1;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 0.6759582 | 0.8680874 | 0.0931455 | 0.2366722 | 0.8598445 | 23 | GNB4;GNG10;LPAR2;GNGT2;GNB2;LPAR5;GNG5 | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6428571 | 0.8539240 | 0.0946646 | 0.2802712 | 0.8597825 | 14 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6836735 | 0.8707693 | 0.0911073 | 0.2645291 | 0.8434335 | 15 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6730769 | 0.8661842 | 0.0886261 | 0.2909569 | 0.8313619 | 11 | MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048 | 0.6695906 | 0.8652956 | 0.0838361 | 0.3431322 | 0.8292870 | 7 | HTRA2;CASP3;CASP9;TRAP1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.7176871 | 0.8974713 | 0.0883594 | 0.2567689 | 0.8186906 | 15 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 0.6802721 | 0.8682236 | 0.0913924 | 0.2648232 | 0.8123930 | 14 | GRB2;BAD;NRAS;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 0.7375415 | 0.8986973 | 0.0855357 | 0.2508815 | 0.8110684 | 16 | ST6GAL1;MGAT1;MOGS;MAN2A1;MGAT2;B4GALT3;B4GALT2;GANAB;MAN1B1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.7375415 | 0.8986973 | 0.0855357 | 0.2507306 | 0.8105805 | 16 | EGFR;PLCG2;CALM3;PPP3CA;CALM2;NFATC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY | 0.7222222 | 0.8986973 | 0.0797706 | 0.3346063 | 0.8086815 | 7 | TNF;TRADD | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.8037736 | 0.9387469 | 0.0878313 | 0.2086773 | 0.7963125 | 30 | GNB4;GNG10;IKBKG;GNGT2;GNB2 | non-significant |
| KEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.8192308 | 0.9449005 | 0.0530213 | 0.5868574 | 0.7958546 | 1 | CCND2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050 | 0.7062147 | 0.8871321 | 0.0791317 | 0.3421698 | 0.7919038 | 6 | BAX;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 0.7912088 | 0.9275724 | 0.0870516 | 0.2116866 | 0.7811058 | 26 | GNB4;GNG10;GNGT2;GNB2;MAP2K2;MAPK1;GNG5;RAF1;MAP2K1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY | 0.7660819 | 0.9119949 | 0.0766747 | 0.3175229 | 0.7673941 | 7 | MAP3K5;TRAF2;MAPK8;MAPK9;ERN1;MAP2K7 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR | 0.7633333 | 0.9119949 | 0.0838361 | 0.2463870 | 0.7510930 | 13 | SQSTM1;UBA52;UBC;RPS27A;UBB;OPTN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY | 0.7627119 | 0.9119949 | 0.0751182 | 0.3244621 | 0.7509219 | 6 | MAP3K5;APP | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8338870 | 0.9501235 | 0.0789210 | 0.2290856 | 0.7406049 | 16 | EGFR;GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY | 0.7706422 | 0.9119949 | 0.0787114 | 0.2631009 | 0.7365539 | 10 | JAK2;IL12RB2;IL12RB1;STAT3;STAT4;TYK2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.7737003 | 0.9122295 | 0.0785029 | 0.2627209 | 0.7354902 | 10 | UQCRFS1;UQCRC1;UQCRH;UQCR10;CYC1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 0.8333333 | 0.9501235 | 0.0802023 | 0.2288352 | 0.7296258 | 15 | IKBKG;PRKD3;SRC;NFKB1;PRKD2;ACP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_C9ORF72_MEDIATED_AUTOPHAGY_INITIATION | 0.8099415 | 0.9406263 | 0.0738053 | 0.3011973 | 0.7279380 | 7 | WDR41;ATG13;RAB1A | non-significant |
| KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.8061224 | 0.9387603 | 0.0819779 | 0.2365824 | 0.7257593 | 14 | SQSTM1;FKBP8;CISD1;CISD2;OPTN | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS | 0.8365385 | 0.9501235 | 0.0768737 | 0.2517949 | 0.7194630 | 11 | GPX1;GPX8;GSS;GPX7;GPX4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_NFKB_SIGNALING_PATHWAY | 0.8163842 | 0.9449005 | 0.0716527 | 0.3106336 | 0.7189179 | 6 | IKBKG;NFKB1;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION | 0.8197279 | 0.9449005 | 0.0810802 | 0.2324997 | 0.7132349 | 14 | MUS81;MAD2L2;ERCC1;FANCI;SLX1A;UBB;DCLRE1A | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.8421053 | 0.9517984 | 0.0718276 | 0.2911669 | 0.7036964 | 7 | IKBKG;NFKB1;NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_INACTIVATION_OF_CONDENSIN_I | 0.8361582 | 0.9501235 | 0.0704501 | 0.3006414 | 0.6957922 | 6 | NCAPG;SMC4;NCAPD2;NCAPH | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN | 0.8470948 | 0.9517984 | 0.0738053 | 0.2481164 | 0.6946047 | 10 | FGG;FCN1;FGB | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.8508772 | 0.9517984 | 0.0713053 | 0.2871993 | 0.6941074 | 7 | BAK1;BAX;CASP3;CASP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55 | 0.8480000 | 0.9517984 | 0.0668966 | 0.3117660 | 0.6844210 | 5 | LAMP2;MAP1LC3A;MAP1LC3B | non-significant |
| KEGG_MEDICUS_VARIANT_DELETED_DMD_TO_DYSTROPHIN_ASSOCIATED_PROTEIN_COMPLEX | 0.8715596 | 0.9668377 | 0.0723571 | 0.2437514 | 0.6823848 | 10 | ACTB;ACTG1;SNTA1;SNTB2;DTNA | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 0.8707483 | 0.9668377 | 0.0778840 | 0.2119630 | 0.6758300 | 15 | GRB2;FLT3LG;NRAS;AKT1;HRAS;PIK3CB;MTOR;PIK3CD;AKT3;PIK3CA;SOS1;AKT2;SOS2;FLT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8936877 | 0.9825084 | 0.0753094 | 0.2090012 | 0.6756746 | 16 | SLC25A5;CASP3;CASP9;VDAC3;SLC25A6;VDAC2;MCU | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP | 0.8918919 | 0.9825084 | 0.0702813 | 0.2491326 | 0.6725337 | 9 | PNP;LACC1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 0.9051988 | 0.9830141 | 0.0704501 | 0.2353432 | 0.6588460 | 10 | SLC25A5;APP;VDAC3;SLC25A6;VDAC2;PPID | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.9314079 | 0.9846534 | 0.0774768 | 0.1808079 | 0.6576348 | 25 | GNB4;GNG10;GNGT2;GNB2;PIK3CG;GNG5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.8841808 | 0.9773356 | 0.0676760 | 0.2804718 | 0.6491125 | 6 | HK3;BAX | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_BIFUNCTIONAL_GLYCOSYLASE | 0.8952096 | 0.9825084 | 0.0699459 | 0.2540320 | 0.6484470 | 8 | PARP2;XRCC1;OGG1;APEX1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_NEF_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.8945578 | 0.9825084 | 0.0764767 | 0.2112348 | 0.6480008 | 14 | IKBKG;MAP3K7;TRADD;NFKB1;TAB2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9013605 | 0.9830141 | 0.0760837 | 0.2014443 | 0.6422917 | 15 | GRB2;MAP2K2;MAPK1;RAF1;MAP2K1;ARAF;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.9219219 | 0.9846534 | 0.0686326 | 0.2365150 | 0.6384724 | 9 | SQSTM1;OPTN | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 0.9409594 | 0.9846534 | 0.0780892 | 0.1691075 | 0.6356188 | 28 | POLR2I;POLR2G;RBX1;GTF2H1;POLR2H;CDK7;ERCC2;POLR2B;GTF2H4;POLR2F;POLR2C;ERCC6;DDB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN | 0.9226667 | 0.9846534 | 0.0628004 | 0.2830920 | 0.6214728 | 5 | CFH;CFI | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION | 0.9101796 | 0.9846534 | 0.0691198 | 0.2432008 | 0.6207991 | 8 | PGM1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION | 0.9320388 | 0.9846534 | 0.0718276 | 0.2077675 | 0.6199274 | 12 | ATG7;ATG5;ATG3;ATG4A | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 0.9711191 | 0.9985428 | 0.0753094 | 0.1657992 | 0.6030451 | 25 | EED;E2F6;EZH2;CBX3;UBB;PCGF6;TFDP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA | 0.9341317 | 0.9846534 | 0.0678338 | 0.2361298 | 0.6027493 | 8 | TGFB1;TGFB2;LTBP4;FBN1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.9523810 | 0.9874771 | 0.0732559 | 0.1852392 | 0.5906228 | 15 | IKBKG;MAP3K7;TRADD;NFKB1;TAB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 0.9900000 | 1.0000000 | 0.0702813 | 0.1695257 | 0.5167867 | 13 | LPAR2;LPAR5;RHOA;GNA13;ARHGEF1;GNA12;LPAR3;ROCK2;LPAR1;ARHGEF11;ROCK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY | 0.9849850 | 1.0000000 | 0.0653834 | 0.1875785 | 0.5063683 | 9 | LPAR2;LPAR5;RHOA | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_HOLLIDAY_JUNCTION_RESOLUTION | 0.9840000 | 1.0000000 | 0.0597318 | 0.2300194 | 0.5049623 | 5 | MUS81;SLX1A | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.9967949 | 1.0000000 | 0.0679923 | 0.1681409 | 0.4804353 | 11 | BAD;AKT1;PIK3CB;PIK3CD;CBL;AKT3;PIK3CA;CRK;ABL1;AKT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_PERK_ATF4_SIGNALING_PATHWAY | 1.0000000 | 1.0000000 | 0.0617054 | 0.2035802 | 0.4711577 | 6 | SOD1;EIF2S1;ATF4 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PERK_ATF4_SIGNALING_PATHWAY | 1.0000000 | 1.0000000 | 0.0617054 | 0.2035802 | 0.4711577 | 6 | PRNP;EIF2S1;ATF4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 1.0000000 | 1.0000000 | 0.0697793 | 0.1434079 | 0.4371685 | 13 | SLC25A5;CASP3;CASP9;VDAC3;SLC25A6;VDAC2;MCU | non-significant |
| KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION | 0.9970060 | 1.0000000 | 0.0646485 | 0.1705913 | 0.4354545 | 8 | RAB5C;RAB5A | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION | 1.0000000 | 1.0000000 | 0.0678338 | 0.1494222 | 0.4269495 | 11 | ADAM17;PSENEN;APH1B;APH1A | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUCONEOGENESIS | 1.0000000 | 1.0000000 | 0.0352404 | -0.2007422 | -0.4029696 | 5 | PCK1;PC;MDH2 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION | 0.9884560 | 1.0000000 | 0.0309901 | -0.1798485 | -0.4681646 | 12 | SEC31B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9895210 | 1.0000000 | 0.0327242 | -0.2104632 | -0.4919658 | 8 | PROK2;MAPK3;PROKR2;PROKR1;GNAI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 0.9929577 | 1.0000000 | 0.0295645 | -0.1558471 | -0.4931594 | 24 | PIGV;PIGL;PGAP1;PIGQ;PIGO;PIGG;PIGM;PIGT;PIGH;DPM2;PIGB;PIGS;PIGU;PIGN | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.9907407 | 1.0000000 | 0.0341205 | -0.2391574 | -0.5118109 | 6 | TCF7L2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9820359 | 1.0000000 | 0.0330894 | -0.2201857 | -0.5146925 | 8 | PROK2;PROK1;MAPK3;PROKR2;GNAI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY | 0.9816384 | 1.0000000 | 0.0302754 | -0.1903619 | -0.5221101 | 14 | TELO2;RRAGA;DEPTOR;SLC7A5;TTI1;RRAGB;FLCN;MLST8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 0.9790732 | 1.0000000 | 0.0331626 | -0.2270977 | -0.5458025 | 9 | KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9653680 | 0.9942808 | 0.0321428 | -0.1919784 | -0.5507284 | 17 | PDGFA;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY | 0.9618644 | 0.9934568 | 0.0312771 | -0.2097618 | -0.5753187 | 14 | TELO2;RRAGA;DEPDC5;DEPTOR;TTI1;RRAGB | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9519774 | 0.9874771 | 0.0317813 | -0.2077063 | -0.5798276 | 15 | FGFR1;KRAS;FGF8 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG7_TO_ALG11 | 0.9629630 | 0.9934568 | 0.0354665 | -0.2721880 | -0.5824984 | 6 | ALG1;ALG2;ALG13 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9502841 | 0.9874771 | 0.0321428 | -0.2001215 | -0.5883475 | 18 | BCL2;KRAS;CHRNB2;CHRNA4;CHRNB4;BRAF;CHRNA3;MAPK3 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 0.9502841 | 0.9874771 | 0.0321428 | -0.2008949 | -0.5906215 | 18 | GRIN2C;SLC25A31;GRIN2A;GRIN2B | non-significant |
| KEGG_MEDICUS_VARIANT_DAB1_OVEREXPRESSION_TO_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.9417040 | 0.9846534 | 0.0350151 | -0.2468048 | -0.5931663 | 9 | RELN | non-significant |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 0.9457143 | 0.9871790 | 0.0326513 | -0.2009146 | -0.5951026 | 19 | PPP2R2C | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_DEGRADATION_BY_EXTRACELLULAR_ENDOLYSOSOMAL_DNASE | 0.9409091 | 0.9846534 | 0.0356933 | -0.2687604 | -0.6004880 | 7 | DNASE1L2;DNASE2B;DNASE1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9300999 | 0.9846534 | 0.0333827 | -0.2129433 | -0.6056470 | 16 | FGFR3;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 0.9350282 | 0.9846534 | 0.0326513 | -0.2173762 | -0.6068220 | 15 | ATG14;TELO2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.9357250 | 0.9846534 | 0.0353157 | -0.2539132 | -0.6102506 | 9 | PROK2;PROK1;MAPK3;PROKR2;PROKR1;GNAI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_NEIL_GLYCOSYLASE | 0.9282511 | 0.9846534 | 0.0356933 | -0.2563166 | -0.6160267 | 9 | POLB;NEIL1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA2_TO_RBP_JK_MEDIATED_TRANSCRIPTION | 0.9303030 | 0.9846534 | 0.0362255 | -0.2760149 | -0.6166966 | 7 | HES1;FCER2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION | 0.9314195 | 0.9846534 | 0.0385579 | -0.3107381 | -0.6237751 | 5 | TAT;HPD;GSTZ1;HGD | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.9408451 | 0.9846534 | 0.0322153 | -0.1975404 | -0.6250930 | 24 | GNG13;GNG3;GNG4;GNGT1;GNG7;PIK3R5;GNB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 0.9548564 | 0.9883881 | 0.0300618 | -0.1901168 | -0.6263904 | 28 | RPA4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION | 0.9212963 | 0.9846534 | 0.0375363 | -0.2936271 | -0.6283794 | 6 | SLC1A6;GRM1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 0.9201141 | 0.9846534 | 0.0338984 | -0.2213093 | -0.6294413 | 16 | PPP2R2C | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_SPRED_AND_NF1 | 0.9151235 | 0.9846534 | 0.0378488 | -0.2983692 | -0.6385276 | 6 | KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.9328671 | 0.9846534 | 0.0322878 | -0.2051864 | -0.6426612 | 23 | CAMK2B;CREB1;CREB3L3;CALM1;CYP11B2;CAMK2A | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS | 0.9186603 | 0.9846534 | 0.0391956 | -0.3203285 | -0.6430268 | 5 | FUT2;B3GALT5;B3GALT1;B3GALT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 0.9081921 | 0.9845375 | 0.0340464 | -0.2347641 | -0.6438932 | 14 | CACNA1D;CACNA1C;SLC25A31 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPG_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.9045455 | 0.9830141 | 0.0375363 | -0.2884560 | -0.6444935 | 7 | BTRC | non-significant |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.8983051 | 0.9830141 | 0.0345664 | -0.2309430 | -0.6446945 | 15 | RELN;TSC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRAPPI_RAB1_SIGNALING_PATHWAY | 0.9028401 | 0.9830141 | 0.0369933 | -0.2709229 | -0.6511312 | 9 | TRAPPC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CN_SIGNALING_PATHWAY | 0.8686869 | 0.9668377 | 0.0371479 | -0.2515249 | -0.6547458 | 12 | NFATC4;CALM1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27 | 0.8753623 | 0.9693189 | 0.0369933 | -0.2567485 | -0.6580479 | 11 | PCGF3;EP300;AUTS2;RYBP;RNF2;YAF2;FBRS | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.8518519 | 0.9517984 | 0.0392759 | -0.2758257 | -0.6835668 | 10 | COLEC11;MBL2;MASP1;MASP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 0.8516949 | 0.9517984 | 0.0370705 | -0.2499221 | -0.6976760 | 15 | CCND1;EP300;TP53;CDK6;RB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY | 0.8318841 | 0.9501235 | 0.0393562 | -0.2722590 | -0.6978015 | 11 | ACVR2B;SMAD9;BMPR2;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 0.8487874 | 0.9517984 | 0.0376923 | -0.2454742 | -0.6981705 | 16 | TERT | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.8333333 | 0.9501235 | 0.0380842 | -0.2541358 | -0.7094392 | 15 | CAMK2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 0.8632011 | 0.9627414 | 0.0349401 | -0.2158140 | -0.7110567 | 28 | GNG13;GNG3;GNG4;MAPK10;GNGT1;GNG7;PIK3R5;GNB3 | non-significant |
| KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.8318182 | 0.9501235 | 0.0414044 | -0.3191607 | -0.7130968 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_FKTN_TO_LARGE | 0.9041812 | 0.9830141 | 0.0439759 | -0.4597321 | -0.7134334 | 2 | FKTN;FKRP | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 0.8485714 | 0.9517984 | 0.0377705 | -0.2438239 | -0.7221986 | 19 | WNT3;WNT4;WNT2B;WNT5B;WNT16 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 0.8305085 | 0.9501235 | 0.0382417 | -0.2398640 | -0.7223556 | 20 | BCORL1;USP7;AEBP2;BCOR | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION | 0.7979798 | 0.9337420 | 0.0410713 | -0.2776954 | -0.7228704 | 12 | CREBBP;CREB1;CREB3L3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS | 0.8494272 | 0.9517984 | 0.0439759 | -0.3892919 | -0.7306066 | 4 | CYP2A6;CYP2A13 | non-significant |
| KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY | 0.7893939 | 0.9272009 | 0.0438002 | -0.3346401 | -0.7476822 | 7 | GHR | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8068182 | 0.9387603 | 0.0398407 | -0.2572202 | -0.7562149 | 18 | PLCB1;ATXN2;SLC25A31;GRM1;ATXN3;PLCB4;VDAC1;GNAQ;CYCS;SLC25A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2 | 0.7604618 | 0.9119949 | 0.0432769 | -0.2907342 | -0.7568116 | 12 | PCGF3;CSNK2A1;AUTS2;RYBP;CSNK2A2;RNF2;YAF2;FBRS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.7711864 | 0.9119949 | 0.0416557 | -0.2780105 | -0.7625061 | 14 | CAMK2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE | 0.7824074 | 0.9207418 | 0.0450443 | -0.3568436 | -0.7636664 | 6 | COLEC11;MBL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 0.8186739 | 0.9449005 | 0.0369161 | -0.2242142 | -0.7639666 | 32 | GNG13;GNG3;LPAR4;GNG4;CHRM1;GNGT1;GNG7;F2R;PIK3R5;GNB3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7542373 | 0.9118611 | 0.0426734 | -0.2811179 | -0.7710287 | 14 | KIT;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS | 0.7681159 | 0.9119949 | 0.0430173 | -0.3014368 | -0.7725842 | 11 | ACSL3;ACSBG1;CPT1B;CPT1C;CPT1A;ACSBG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 0.7720280 | 0.9119949 | 0.0411544 | -0.2495197 | -0.7815169 | 23 | ESR1;KRAS;CREB1;CREB3L3;ESR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HYDROLYSIS_OF_SPHINGOMYELIN | 0.7606061 | 0.9119949 | 0.0454968 | -0.3500134 | -0.7820306 | 7 | SMPD3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_LOADING | 0.7683109 | 0.9119949 | 0.0444181 | -0.3260196 | -0.7835498 | 9 | DDX11;ATRX;RAD21;MAU2;NIPBL | non-significant |
| KEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION | 0.7629630 | 0.9119949 | 0.0443293 | -0.3172891 | -0.7863239 | 10 | AHCYL2;MAT2A;AHCYL1;MAT1A;DNMT3B | non-significant |
| KEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION | 0.7560606 | 0.9119949 | 0.0457704 | -0.3544275 | -0.7918929 | 7 | IVD;AUH;HMGCL;HMGCLL1;MCCC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.7324930 | 0.8986973 | 0.0436251 | -0.2590065 | -0.7920460 | 21 | PLCB1;NFATC4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 0.7245763 | 0.8986973 | 0.0445071 | -0.2868677 | -0.8008124 | 15 | GRIN2C;SLC25A31;GRIN2A;GRIN2B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.7361111 | 0.8986973 | 0.0478300 | -0.3750580 | -0.8026461 | 6 | SNCA;HSPA5 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.7325103 | 0.8986973 | 0.0426734 | -0.2472152 | -0.8027931 | 26 | IGF1R;MLLT3;CCNT2;KMT2A;SMAD1;CDKN1B;CDK9;HMGA2;SUPT3H;FLT3;AFF1;CCNT1;KLF3;MLLT1;RUNX2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 0.7471429 | 0.9050517 | 0.0436251 | -0.2719703 | -0.8055673 | 19 | GRIN2C;HTT;SLC25A31;GRIN2A;GRIN2B | non-significant |
| KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY | 0.7443946 | 0.9034907 | 0.0458620 | -0.3363116 | -0.8082853 | 9 | SLC2A1;TGFB3;VEGFA;TGFA | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 0.7343750 | 0.8986973 | 0.0441523 | -0.2751715 | -0.8089911 | 18 | IFNA4;IFNA6;IRF9;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.7410180 | 0.9011594 | 0.0461379 | -0.3466712 | -0.8103571 | 8 | PTK2 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR | 0.7283951 | 0.8986973 | 0.0483118 | -0.3794123 | -0.8119647 | 6 | CFHR4;CFHR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 0.7313433 | 0.8986973 | 0.0422468 | -0.2417258 | -0.8133475 | 30 | DYNLRB2;DYNC1I1;ACTR10;DYNC2H1;DCTN4 | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_STRAND_BREAK_SIGNALING | 0.7202899 | 0.8986973 | 0.0459538 | -0.3177183 | -0.8143140 | 11 | RAD50;PIAS4;ATM;HERC2;UBE2V2;RNF8 | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING | 0.7150997 | 0.8960460 | 0.0454968 | -0.3056601 | -0.8155598 | 13 | PAXIP1;LIG4;PRKDC;POLL;DNTT;POLM;TP53BP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_MONOFUNCTIONAL_GLYCOSYLASE | 0.7350299 | 0.8986973 | 0.0465084 | -0.3491574 | -0.8161686 | 8 | POLB;SMUG1;UNG | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY | 0.7012987 | 0.8859263 | 0.0469759 | -0.3143642 | -0.8183230 | 12 | SLC2A1;TGFB3;VEGFA;VHL;TGFA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6920904 | 0.8778770 | 0.0466015 | -0.2943358 | -0.8216603 | 15 | CCND1;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P15_CELL_CYCLE_G1_S | 0.7065527 | 0.8871321 | 0.0460458 | -0.3082080 | -0.8223581 | 13 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE | 0.7240829 | 0.8986973 | 0.0500923 | -0.4113850 | -0.8258135 | 5 | XYLT1;B3GALT6;XYLT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 0.7031250 | 0.8864244 | 0.0461379 | -0.2840936 | -0.8352216 | 18 | CAMK2B;CAMKK1;CALM1;MYLK3;MYLK2;CAMK2A | non-significant |
| KEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION | 0.6874074 | 0.8737273 | 0.0490940 | -0.3398724 | -0.8422911 | 10 | ACADSB | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S | 0.7010463 | 0.8859263 | 0.0486034 | -0.3508589 | -0.8432481 | 9 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 0.6724387 | 0.8661842 | 0.0488971 | -0.2944182 | -0.8445974 | 17 | IFNA4;IFNA6;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 0.6780627 | 0.8682236 | 0.0479259 | -0.3177858 | -0.8479134 | 13 | PDGFA | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.6483051 | 0.8572856 | 0.0495902 | -0.3102908 | -0.8510420 | 14 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_V_D_J_RECOMBINATION | 0.6652237 | 0.8614507 | 0.0493910 | -0.3271125 | -0.8515081 | 12 | LIG4;RAG1;RAG2;PRKDC;POLL;DNTT;POLM | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY | 0.6623377 | 0.8612843 | 0.0495902 | -0.3281306 | -0.8541584 | 12 | PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS | 0.6637037 | 0.8612843 | 0.0507028 | -0.3460406 | -0.8575775 | 10 | SHC2;SHC4;SHC3 | non-significant |
| KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6797101 | 0.8682236 | 0.0486034 | -0.3349393 | -0.8584515 | 11 | RET;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_SIGNALING | 0.6594517 | 0.8611827 | 0.0497903 | -0.3307457 | -0.8609659 | 12 | RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY | 0.6571856 | 0.8600379 | 0.0516356 | -0.3705680 | -0.8662167 | 8 | SMAD3;TGFB3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6509972 | 0.8572856 | 0.0497903 | -0.3250000 | -0.8671623 | 13 | ITPR2 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6509972 | 0.8572856 | 0.0497903 | -0.3250782 | -0.8673710 | 13 | MEIS1;HOXA11;HPGD;KMT2A;GRIA3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.6276748 | 0.8427997 | 0.0515309 | -0.3050840 | -0.8677108 | 16 | CREB1;ADCY5;PRKACG;DRD1;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION | 0.6497006 | 0.8572856 | 0.0521630 | -0.3726705 | -0.8711315 | 8 | IDUA;HYAL1;SPAM1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S | 0.6608696 | 0.8612174 | 0.0498907 | -0.3414548 | -0.8751507 | 11 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION | 0.6560606 | 0.8600379 | 0.0522693 | -0.3930596 | -0.8782082 | 7 | IDUA;HGSNAT | non-significant |
| KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 0.6523126 | 0.8572856 | 0.0549074 | -0.4402007 | -0.8836579 | 5 | CYP11B2;CYP21A2;CYP11B1;HSD11B2;CYP17A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 0.6316508 | 0.8447867 | 0.0491928 | -0.2665109 | -0.8859505 | 29 | ADCY1;ADCY9;ADCY8;CREB1;ADCY5;PRKACG;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN | 0.6373457 | 0.8489280 | 0.0544556 | -0.4141583 | -0.8863232 | 6 | ATG14;EPM2A;UVRAG;PIK3R4;BECN1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 0.6267806 | 0.8427997 | 0.0515309 | -0.3327643 | -0.8878790 | 13 | ITPR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 0.6169631 | 0.8375003 | 0.0503964 | -0.2703845 | -0.8908536 | 28 | WNT3;WNT4;FRZB;WIF1;WNT2B;WNT5B;WNT16;SFRP1;WNT9B;SFRP5;CER1;WNT8B;WNT8A | non-significant |
| KEGG_MEDICUS_REFERENCE_BILE_ACID_BIOSYNTHESIS | 0.6059322 | 0.8340381 | 0.0526973 | -0.3259568 | -0.8940094 | 14 | ACOX2;HSD17B4;AKR1D1;CYP7A1;AKR1C4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 0.5953361 | 0.8265327 | 0.0521630 | -0.2753287 | -0.8940874 | 26 | ITGA7;ITGA2;PTK2;ITGB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.5966387 | 0.8265327 | 0.0530213 | -0.2924685 | -0.8943735 | 21 | PLCB1;CGA | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION | 0.6318841 | 0.8447867 | 0.0519512 | -0.3493113 | -0.8952869 | 11 | ACADSB | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.6188272 | 0.8381926 | 0.0558265 | -0.4216973 | -0.9024570 | 6 | ATG14 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 0.6231884 | 0.8422568 | 0.0525899 | -0.3521252 | -0.9024990 | 11 | RYR2;CACNA1C;CALM1;CACNA1S;RYR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1 | 0.6103704 | 0.8340381 | 0.0545681 | -0.3644875 | -0.9032937 | 10 | ATG14;WIPI2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 0.6265390 | 0.8427997 | 0.0496901 | -0.2674218 | -0.9044725 | 31 | BMI1;CBX6;SCML2;AEBP2;PHC1;PHC3;LCORL;EZH1;LCOR | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCND1_TO_CELL_CYCLE_G1_S | 0.6080247 | 0.8340381 | 0.0566484 | -0.4248144 | -0.9091279 | 6 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 0.6028571 | 0.8329656 | 0.0534572 | -0.3075178 | -0.9108577 | 19 | IFNA4;IFNA6;IFNA8;MAVS;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_STRAD_STK11_TSC_SIGNALING_PATHWAY | 0.5943114 | 0.8265327 | 0.0562941 | -0.3906371 | -0.9131291 | 8 | PRKAA2;TSC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.6073871 | 0.8340381 | 0.0511148 | -0.2705673 | -0.9151111 | 31 | PLCB1;PTK2;GNG13;GNG3;GNG4 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BPA_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5968661 | 0.8265327 | 0.0537873 | -0.3436427 | -0.9169047 | 13 | ESR1;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S | 0.5913174 | 0.8265327 | 0.0565300 | -0.3924668 | -0.9174061 | 8 | CCND1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.5661972 | 0.8082962 | 0.0557104 | -0.2922235 | -0.9247066 | 24 | ADCY1;ADCY9;ADCY8;CREB1;ADCY5;PRKACG;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 0.5564972 | 0.8010971 | 0.0566484 | -0.3316130 | -0.9257225 | 15 | IFNA4;IFNA6;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S | 0.5916306 | 0.8265327 | 0.0547940 | -0.3561215 | -0.9270218 | 12 | CCND1;TP53;MDM2;CDK6;RB1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.5508475 | 0.7966696 | 0.0571259 | -0.3392192 | -0.9303847 | 14 | CAMK2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.5445816 | 0.7950378 | 0.0562941 | -0.2867059 | -0.9310330 | 26 | ADCY1;ADCY9;ADCY8;CREB1;ADCY5;PRKACG;CREB3L3;GNAO1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.5418381 | 0.7929026 | 0.0565300 | -0.2870341 | -0.9320986 | 26 | ADCY1;ADCY9;CRH;ADCY8;CREB1;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN | 0.5658683 | 0.8082962 | 0.0585938 | -0.3987752 | -0.9321523 | 8 | COLEC11;MBL2;MASP2;F2;COLEC10 | non-significant |
| KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY | 0.5718519 | 0.8101615 | 0.0576091 | -0.3772293 | -0.9348712 | 10 | PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSC1_2_MTORC1_SIGNALING_PATHWAY | 0.5782609 | 0.8150201 | 0.0560596 | -0.3658204 | -0.9375998 | 11 | TSC1;TELO2;TSC2;DEPTOR;RHEB;TTI1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5278174 | 0.7853821 | 0.0596037 | -0.3336695 | -0.9490128 | 16 | ESR1;CHRNA9;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.5216783 | 0.7837837 | 0.0592219 | -0.3034056 | -0.9502920 | 23 | ITGA7;ITGA2;PTK2;ITGB3 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.5385714 | 0.7899898 | 0.0587186 | -0.3212608 | -0.9515642 | 19 | ITPR2;RYR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 0.5216783 | 0.7837837 | 0.0592219 | -0.3038119 | -0.9515647 | 23 | ITGA7;ITGA2;ARHGAP35;ITGB3 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_RASSF1_TO_RAS_RASSF1_SIGNALING_PATHWAY | 0.5293210 | 0.7857307 | 0.0632191 | -0.4518669 | -0.9670219 | 6 | KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION | 0.5378788 | 0.7899898 | 0.0615707 | -0.4330964 | -0.9676619 | 7 | HTT;BDNF;REST;RCOR1;HDAC1;SIN3A | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 0.5113636 | 0.7793801 | 0.0609039 | -0.3293860 | -0.9683789 | 18 | IFNA4;IFNA6;IFNA8;MAVS;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS | 0.5239521 | 0.7852938 | 0.0622490 | -0.4148902 | -0.9698216 | 8 | CHSY3;CHST7;CHST3;CSGALNACT1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5042373 | 0.7772130 | 0.0613026 | -0.3481205 | -0.9718043 | 15 | FGFR2;FGFR1;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.5277778 | 0.7853821 | 0.0633597 | -0.4541421 | -0.9718908 | 6 | CACNA1D;CACNA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 0.4978602 | 0.7762606 | 0.0623861 | -0.3418774 | -0.9723577 | 16 | IGF1R;IGF2;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5021645 | 0.7770996 | 0.0625237 | -0.3756724 | -0.9779147 | 12 | CCND1;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 0.4852321 | 0.7663109 | 0.0629395 | -0.3168355 | -0.9799381 | 22 | PPP2R2C;CD86 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 0.5047490 | 0.7772130 | 0.0593488 | -0.2916043 | -0.9811764 | 30 | ITGA7;ITGA2;PTK2;DOCK1;ITGB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 0.5089820 | 0.7793801 | 0.0636424 | -0.4200019 | -0.9817704 | 8 | ATP2A1;ELN;ATP2A2;MLN;ATP2A3;SLN;PLN | non-significant |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.4792244 | 0.7663109 | 0.0628004 | -0.3011330 | -0.9837042 | 27 | ADCY1;ADCY9;CRH;ADCY8;CREB1;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_ | 0.5066667 | 0.7782299 | 0.0691198 | -0.5735759 | -0.9867175 | 3 | MGAM | non-significant |
| KEGG_MEDICUS_REFERENCE_AHR_SIGNALING_PATHWAY | 0.4865269 | 0.7663109 | 0.0658312 | -0.4268671 | -0.9978181 | 8 | IL22;VEGFA;CYP1A1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.4687500 | 0.7618518 | 0.0650878 | -0.3405235 | -1.0011226 | 18 | PLCB1;NFATC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 0.4618644 | 0.7563335 | 0.0655321 | -0.3600741 | -1.0051738 | 15 | RPA4;BRCA1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY | 0.4603175 | 0.7557998 | 0.0667426 | -0.3867782 | -1.0068245 | 12 | IFNA4;IFNA6;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION | 0.4565217 | 0.7515611 | 0.0673624 | -0.3958155 | -1.0144774 | 11 | RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 0.4469357 | 0.7397145 | 0.0699459 | -0.4237832 | -1.0185130 | 9 | CREBBP;EP300 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY | 0.4444444 | 0.7387885 | 0.0684715 | -0.3925207 | -1.0217726 | 12 | CCND1;APC;TCF7L2 | non-significant |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 0.4405594 | 0.7370440 | 0.0673624 | -0.3262380 | -1.0218052 | 23 | CACNA1H;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 0.4350205 | 0.7370440 | 0.0668966 | -0.3107063 | -1.0237046 | 28 | ADCY1;ADCY9;GHRH;ADCY8;CREB1;ADCY5;PRKACG;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 0.4207723 | 0.7367644 | 0.0672065 | -0.2957937 | -1.0239181 | 35 | ADCY1;ADCY9;ARID1A;SMARCD3;KDM3B;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION | 0.4439462 | 0.7387885 | 0.0702813 | -0.4260474 | -1.0239548 | 9 | C7;C6;C9;C8B;VTN;C8A;C8G | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 0.4279601 | 0.7370440 | 0.0697793 | -0.3610068 | -1.0267650 | 16 | CCND1;PGR;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY | 0.4394619 | 0.7370440 | 0.0707899 | -0.4279312 | -1.0284823 | 9 | SMAD9;BMPR2;SMAD1;BMP10;SMAD5;ACVR2A;GDF2;ACVRL1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4227994 | 0.7367644 | 0.0709609 | -0.3585942 | -1.0286992 | 17 | PBX1;NR4A1;CREB1;STAR;CREB3L3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4303977 | 0.7370440 | 0.0692836 | -0.3500346 | -1.0290850 | 18 | PBX1;NR4A1;CREB1;STAR;CREB3L3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY | 0.4222222 | 0.7367644 | 0.0723571 | -0.4152761 | -1.0291607 | 10 | CCND1;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.4213564 | 0.7367644 | 0.0711327 | -0.3588639 | -1.0294728 | 17 | ADCY1;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 0.4311377 | 0.7370440 | 0.0718276 | -0.4421473 | -1.0335361 | 8 | PGR | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_PAI | 0.4506173 | 0.7438189 | 0.0711327 | -0.4835516 | -1.0348290 | 6 | SERPINA5;PLAT | non-significant |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 0.4041451 | 0.7262250 | 0.0678338 | -0.2909338 | -1.0367114 | 42 | TUBB2B;DNALI1;DNAI1;DNAH5;DNAH7;DNAH9;ACTR10;DNAH12;TUBA8;DNAH2;DCTN4;DNAH10;TUBB1;DNAH6 | non-significant |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4237288 | 0.7367644 | 0.0697793 | -0.3715267 | -1.0371445 | 15 | IGF1R;IGF2;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 0.4145658 | 0.7367644 | 0.0704501 | -0.3403164 | -1.0406932 | 21 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION | 0.4045584 | 0.7262250 | 0.0725352 | -0.3915360 | -1.0446931 | 13 | PPARGC1A;CREB1;HTT;CREB3L3;TAF4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.4153846 | 0.7367644 | 0.0702813 | -0.3339322 | -1.0459040 | 23 | ADCY1;ADCY9;ADCY8;CREB1;ADCY5;PRKACG;CREB3L3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.4069930 | 0.7281175 | 0.0713053 | -0.3357580 | -1.0516227 | 23 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.4025424 | 0.7262250 | 0.0723571 | -0.3836560 | -1.0522626 | 14 | IGF1R | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.3965763 | 0.7262250 | 0.0736213 | -0.3707638 | -1.0545155 | 16 | ADCY1;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.3830911 | 0.7146174 | 0.0714786 | -0.3034274 | -1.0595088 | 37 | CCND1;LRP6;WNT3;WNT4;APC;WNT2B;TCF7L2;WNT5B;WNT16;FRAT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY | 0.3855072 | 0.7146174 | 0.0758887 | -0.4139258 | -1.0608941 | 11 | PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 0.4011299 | 0.7262250 | 0.0725352 | -0.3531823 | -1.0636162 | 20 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY | 0.3777778 | 0.7107734 | 0.0780892 | -0.4319555 | -1.0704965 | 10 | MAP3K10;MAP3K12;MAPK10 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY | 0.3855932 | 0.7146174 | 0.0745501 | -0.3904749 | -1.0709650 | 14 | IFNA4;IFNA6;IFNA8;IFNA10;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 0.3419355 | 0.6762238 | 0.0760837 | -0.3013281 | -1.0829599 | 44 | TUBB2B;DNALI1;DNAI1;DNAH5;DNAH7;DNAH9;ACTR10;DNAH12;TUBA8;HTT;DNAH2;DCTN4;DNAH10;TUBB1;DNAH6 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR | 0.3657407 | 0.6902241 | 0.0819779 | -0.5068321 | -1.0846506 | 6 | ACVR2B;BMPR2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.3459916 | 0.6790717 | 0.0799859 | -0.3530915 | -1.0920741 | 22 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 0.3466667 | 0.6790717 | 0.0826646 | -0.4411048 | -1.0931710 | 10 | CD86 | non-significant |
| KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY | 0.3512706 | 0.6834019 | 0.0824344 | -0.4565996 | -1.0973834 | 9 | BMPR1B;SMAD9;AMHR2;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP | 0.3398204 | 0.6748212 | 0.0843144 | -0.4721852 | -1.1037509 | 8 | KRAS;RASA3;RASA4 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 0.3578644 | 0.6879442 | 0.0795565 | -0.4247759 | -1.1057364 | 12 | ESR1;CHRNA9 | non-significant |
| KEGG_MEDICUS_VARIANT_EWSR1_WT1_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.3287037 | 0.6641133 | 0.0878313 | -0.5216456 | -1.1163523 | 6 | BAIAP3;PDGFA;TSPAN7 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.3318903 | 0.6648547 | 0.0835991 | -0.3903830 | -1.1198917 | 17 | CAMK2B;PDGFA | non-significant |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 0.3220339 | 0.6558174 | 0.0840746 | -0.4016773 | -1.1213121 | 15 | ADCY1;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY | 0.3124066 | 0.6424574 | 0.0888945 | -0.4675716 | -1.1237533 | 9 | THRA;RXRA | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.3220816 | 0.6558174 | 0.0838361 | -0.3639324 | -1.1256037 | 22 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381 | 0.3304473 | 0.6641133 | 0.0838361 | -0.4348611 | -1.1319892 | 12 | HEY1;NOTCH4;HES1;MAML3;NOTCH3;RBPJL | non-significant |
| KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY | 0.2992593 | 0.6300731 | 0.0908241 | -0.4596035 | -1.1390155 | 10 | ADCY9;AVPR2;PRKACG | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY | 0.3030303 | 0.6337019 | 0.0913924 | -0.5107626 | -1.1411904 | 7 | CCND1;TCF7L2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME | 0.3015152 | 0.6326708 | 0.0916795 | -0.5117899 | -1.1434856 | 7 | PRKACG;PRKAR2B;PRKAR2A;PRKACB;PRKAR1B | non-significant |
| KEGG_MEDICUS_REFERENCE_RENIN_ANGIOTENSIN_SIGNALING_PATHWAY | 0.2886762 | 0.6234891 | 0.0972151 | -0.5699981 | -1.1442131 | 5 | AGTR1;AGTR2;REN | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_MESP2_SIGNALING | 0.2870813 | 0.6234891 | 0.0975449 | -0.5705505 | -1.1453219 | 5 | EPHA4;RIPPLY2;TBX6 | non-significant |
| KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY | 0.2924242 | 0.6234891 | 0.0934449 | -0.5131877 | -1.1466088 | 7 | PLCB1;CASR;PTH | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_ITPR1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.2924242 | 0.6234891 | 0.0934449 | -0.5132216 | -1.1466846 | 7 | PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.2941176 | 0.6234891 | 0.0873098 | -0.3480737 | -1.1468216 | 28 | CAMK2B;PLCB1;AGTR1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_RXRA_LXRA_MEDIATED_TRANSCRIPTION | 0.2716049 | 0.6069439 | 0.0988903 | -0.5368077 | -1.1488001 | 6 | CCND1;RXRA | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 0.2923729 | 0.6234891 | 0.0894367 | -0.4128697 | -1.1525566 | 15 | KITLG;KIT;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.2735426 | 0.6079319 | 0.0965630 | -0.4830366 | -1.1609217 | 9 | VPS18;VPS41 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_REPRESSION | 0.2577160 | 0.5990373 | 0.1020801 | -0.5443749 | -1.1649944 | 6 | NGFR | non-significant |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2900433 | 0.6234891 | 0.0911073 | -0.4063842 | -1.1657944 | 17 | LEP;GHR;PRL;CSF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 0.2546296 | 0.5981370 | 0.1028218 | -0.5463040 | -1.1691229 | 6 | MAGI1;MAGI2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 0.2792023 | 0.6152095 | 0.0925529 | -0.4384385 | -1.1698381 | 13 | IGF1R;TSC1;IGF1;TSC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2714286 | 0.6069439 | 0.0943564 | -0.3964175 | -1.1741759 | 19 | IFNK;IFNA4;IFNW1;IFNA6;IFNE;IRF9;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 0.2740113 | 0.6079319 | 0.0931455 | -0.4217508 | -1.1773489 | 15 | ADCY1;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION | 0.2409091 | 0.5825107 | 0.1051251 | -0.5283352 | -1.1804527 | 7 | C7;C6;C9;C8B;C5;C8A;C8G | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 0.2655367 | 0.6029221 | 0.0949752 | -0.4322660 | -1.1855865 | 14 | RPA4;BRCA1 | non-significant |
| KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.2440120 | 0.5877176 | 0.1035763 | -0.5092634 | -1.1904226 | 8 | CCND1;TCF7L2 | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 0.2117177 | 0.5420612 | 0.1051251 | -0.3454760 | -1.1958983 | 35 | FGFR2;FGFR3;FGFR1;KRAS;FGF5;FGF10;FGF7;FGF8;FGF20;FGF2;FGF18;FGF17;FGF19;FGF3;FGF23;BRAF;FGF16;FGF22;MAPK3;SOS2;FGFR4 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS | 0.2391304 | 0.5825107 | 0.1028218 | -0.4679601 | -1.1993845 | 11 | EXTL1;NDST1;GLCE;HS6ST1;NDST3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_CAMP_SIGNALING_PATHWAY | 0.2471751 | 0.5884670 | 0.0992333 | -0.4399943 | -1.2067829 | 14 | ADCY1;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RAS_UBIQUITINATION_BY_CUL3_COMPLEX | 0.2237654 | 0.5607725 | 0.1110115 | -0.5651747 | -1.2095072 | 6 | KRAS;CUL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 0.2185629 | 0.5522058 | 0.1105647 | -0.5193335 | -1.2139619 | 8 | CDON;LRP2 | non-significant |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.1709986 | 0.4811280 | 0.1209851 | -0.3663885 | -1.2391968 | 31 | ADCY1;PBX1;ADCY9;NR4A1;MRAP;ADCY8;CREB1;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.1990741 | 0.5134452 | 0.1188150 | -0.5791058 | -1.2393206 | 6 | PLCB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.1944444 | 0.5078528 | 0.1204334 | -0.5813402 | -1.2441024 | 6 | MAP3K10;MAPK10;HTT | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY | 0.1893939 | 0.4995964 | 0.1209851 | -0.5582425 | -1.2472741 | 7 | BMPR1B;SMAD9;BMPR2;SMAD1;BMP15 | non-significant |
| KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY | 0.1971014 | 0.5126294 | 0.1152400 | -0.4876719 | -1.2499059 | 11 | IFNA4;IFNA6;IFNA8;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 0.1901198 | 0.4995964 | 0.1198878 | -0.5352805 | -1.2512385 | 8 | KIT | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM | 0.1738437 | 0.4826474 | 0.1307771 | -0.6244247 | -1.2534688 | 5 | GRIN2C;GRIN2A;GRIN2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.1811377 | 0.4896256 | 0.1232572 | -0.5369570 | -1.2551574 | 8 | VPS18;VPS41 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 0.1514763 | 0.4471783 | 0.1250334 | -0.3415572 | -1.2595320 | 50 | OXTR;ITPR2;PLCB1;AGTR1;ADRA1B;PTGER3;CHRM1;TACR1;HTR2A;GRPR;LHCGR;GNA14;HTR2C;EDNRB;CYSLTR2;F2R;GRM1;PTGER1;TRHR;TACR3;CHRM3;BDKRB1;NTSR1;PLCB4;AVPR1B;AVPR1A;GNA11;ADRA1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.1779310 | 0.4851952 | 0.1188150 | -0.3909363 | -1.2600255 | 25 | CACNA1H;CAMK2B;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL | 0.1826087 | 0.4914556 | 0.1204334 | -0.4921893 | -1.2614840 | 11 | GRIN2C;P2RX2;GRIN2A;P2RX1;P2RX6 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.1718310 | 0.4812823 | 0.1226792 | -0.3997010 | -1.2648061 | 24 | CACNA1H;CAMK2B;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 0.1594203 | 0.4611269 | 0.1301056 | -0.5000084 | -1.2815244 | 11 | ERBB4;NRG3;NRG1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.1517241 | 0.4471783 | 0.1301056 | -0.3990268 | -1.2861021 | 25 | CACNA1H;CAMK2B;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_POMT_TO_POMK | 0.1435407 | 0.4398598 | 0.1455161 | -0.6441182 | -1.2930016 | 5 | POMT2;POMK;POMT1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.1435185 | 0.4398598 | 0.1429011 | -0.6050207 | -1.2947801 | 6 | ATG14;HTT | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 0.1227621 | 0.3868691 | 0.1404062 | -0.3561606 | -1.2963268 | 46 | CCND1;LRP6;WNT3;FZD9;FZD4;WNT4;FZD6;FZD3;APC;WNT2B;TCF7L2;WNT5B;WNT16;FRAT1;AXIN2;FZD7;WNT9B;WNT8B;FZD1;WNT8A;FZD8;DVL1;FZD10;DVL2 | non-significant |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.1183206 | 0.3794842 | 0.1429011 | -0.3594793 | -1.3042470 | 45 | CCND1;LRP6;WNT3;FZD9;FZD4;WNT4;FZD6;FZD3;APC;WNT2B;TCF7L2;WNT5B;WNT16;FRAT1;AXIN2;FZD7;WNT9B;WNT8B;FZD1;WNT8A;FZD8;DVL1;FZD10;DVL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1652422 | 0.4670543 | 0.1262540 | -0.4911387 | -1.3104523 | 13 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY | 0.1317365 | 0.4118430 | 0.1473312 | -0.5608067 | -1.3109070 | 8 | SMAD3;ACVR2B;ACVR1B;ACVR1C | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST | 0.1623932 | 0.4641408 | 0.1275053 | -0.4928184 | -1.3149340 | 13 | GDF6;BMP4;GREM2;CHRD;BMP8A;BMP5;BMP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 0.1483595 | 0.4457987 | 0.1342735 | -0.4644699 | -1.3210316 | 16 | ADCY1;CGA;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 0.1227545 | 0.3868691 | 0.1531588 | -0.5659958 | -1.3230367 | 8 | RET | non-significant |
| KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.1500722 | 0.4466089 | 0.1342735 | -0.5090301 | -1.3250590 | 12 | PLCB1;TRH | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.1096076 | 0.3717525 | 0.1541910 | -0.3899768 | -1.3287708 | 32 | ADCY1;PBX1;ADCY9;NR4A1;MRAP;ADCY8;CREB1;STAR;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 0.1369472 | 0.4238516 | 0.1404062 | -0.4685887 | -1.3327461 | 16 | ADCY1;CGA;ADCY9;ADCY8;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 0.1355207 | 0.4215442 | 0.1412251 | -0.4695384 | -1.3354471 | 16 | IFNA4;IKBKB;IFNA6;IFNA8;MAVS;IFNA10;IFNB1;IFNA21;IFNA5;IFNA2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.1159618 | 0.3784212 | 0.1501698 | -0.4024014 | -1.3376851 | 29 | ADCY1;PBX1;ADCY9;NR4A1;ADCY8;CREB1;STAR;ADCY5;PRKACG | non-significant |
| KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1457431 | 0.4432311 | 0.1364904 | -0.5140700 | -1.3381783 | 12 | KIF5C;CSNK2A1;KLC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY | 0.1122754 | 0.3747033 | 0.1608014 | -0.5741169 | -1.3420201 | 8 | MSTN;ACVR2B;SMAD9;ACVR1B;SMAD1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.1105048 | 0.3717525 | 0.1541910 | -0.4065919 | -1.3516154 | 29 | GLI3;GLI1;WNT3;WNT4;BMP4;SMO;WNT2B;HHIP;WNT5B;KIF7;WNT16 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.1105048 | 0.3717525 | 0.1541910 | -0.4065919 | -1.3516154 | 29 | GLI3;GLI1;WNT3;WNT4;BMP4;SMO;WNT2B;HHIP;WNT5B;KIF7;WNT16 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY | 0.1125926 | 0.3747033 | 0.1596467 | -0.5487813 | -1.3600211 | 10 | CCND1;APC;TCF7L2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1144928 | 0.3769735 | 0.1563124 | -0.5349517 | -1.3710845 | 11 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0927978 | 0.3263740 | 0.1709323 | -0.4199236 | -1.3717547 | 27 | DNALI1;DNAI1;DNAH5;DNAH7;DNAH9;ACTR10;DNAH12;DNAH2;DCTN4;DNAH10;DNAH6 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 0.0885714 | 0.3232489 | 0.1782199 | -0.4654385 | -1.3786138 | 19 | GDF6;BMP4;BMPR1B;ACVR2B;SMAD9;BMPR2;SMAD1;BMP8A;BMP5;BMP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 0.0926756 | 0.3263740 | 0.1782199 | -0.5752557 | -1.3825592 | 9 | PAQR5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.0875706 | 0.3232489 | 0.1782199 | -0.4604664 | -1.3867045 | 20 | PDE8B;PBX1;NR4A1;PDE11A;CREB1;STAR;CREB3L3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM | 0.0910494 | 0.3239056 | 0.1830239 | -0.6494388 | -1.3898374 | 6 | GRIN2C;PDYN;GRIN2A;GRIN2B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.0903704 | 0.3233483 | 0.1797823 | -0.5670044 | -1.4051825 | 10 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 0.0854701 | 0.3206423 | 0.1813831 | -0.5312756 | -1.4175451 | 13 | GLI3;GLI1;SMO;HHIP;KIF7;EVC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0777280 | 0.3007860 | 0.1957890 | -0.5911928 | -1.4208623 | 9 | KIF5C;KLC3;KLC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR | 0.0748588 | 0.2951438 | 0.1938133 | -0.5200609 | -1.4263836 | 14 | VPS18;TECPR2;VPS41;EPG5;BIRC6;MAP1LC3C;VPS16 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382 | 0.0726496 | 0.2914313 | 0.1978220 | -0.5376425 | -1.4345333 | 13 | HEY1;NOTCH4;HES1;MAML3;NOTCH3;RBPJL;NFX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY | 0.0553892 | 0.2348351 | 0.2343926 | -0.6216854 | -1.4532134 | 8 | SMAD3;ACVR2B;NODAL;ACVR1B;ACVR1C | non-significant |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 0.0548697 | 0.2342368 | 0.2249661 | -0.4479605 | -1.4546824 | 26 | FOXK1;BMI1;CBX6;SCML2;PHC1;PHC3;MBD5;MBD6;ASXL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CREATINE_PATHWAY | 0.0601852 | 0.2500311 | 0.2279872 | -0.6815252 | -1.4585042 | 6 | GAMT;CKMT2;GATM | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 0.0478796 | 0.2147644 | 0.2413400 | -0.4343082 | -1.4689144 | 31 | FGFR2;FGFR3;FGFR1;FGF5;FGF10;FGF7;FGF8;FGF20;FGF2;FGF18;FGF17;FGF19;FGF3;FGF23 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY | 0.0509259 | 0.2235684 | 0.2489111 | -0.6878242 | -1.4719843 | 6 | ITPR2;PLCD4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380 | 0.0678211 | 0.2798749 | 0.2065879 | -0.5680924 | -1.4788042 | 12 | HEY1;NOTCH4;JAG1;HES1;MAML3;NOTCH3;RBPJL | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GRM1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.0493274 | 0.2196664 | 0.2489111 | -0.6184111 | -1.4862783 | 9 | ITPR2;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 0.0513552 | 0.2238653 | 0.2377938 | -0.5241032 | -1.4906387 | 16 | FZD9;FZD4;FZD6;FZD3;ROR2;FZD7;FZD1;FZD8;DVL1;FZD10;DVL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0498575 | 0.2204416 | 0.2413400 | -0.5623518 | -1.5004624 | 13 | IL20;IL24;IL19;IL26;IL22 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 0.0420290 | 0.1941488 | 0.2663507 | -0.5960037 | -1.5275609 | 11 | IGF1R;IGF2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS | 0.0148139 | 0.0899000 | 0.3807304 | -0.8145699 | -1.5287504 | 4 | SULT1A2;SULT1A4;SULT1A1;CYP1A2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0351918 | 0.1705530 | 0.3217759 | -0.4743711 | -1.5496171 | 27 | DNALI1;DNAI1;DNAH5;DNAH7;DNAH9;ACTR10;DNAH12;DNAH2;DCTN4;DNAH10;DNAH6 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 0.0224240 | 0.1228358 | 0.3524879 | -0.5443302 | -1.6003046 | 18 | RNF43;FZD9;FZD4;FZD6;RSPO1;FZD3;ZNRF3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 0.0153186 | 0.0911750 | 0.3807304 | -0.6799536 | -1.6341884 | 9 | FGFR2;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 0.0089632 | 0.0616470 | 0.3807304 | -0.8201388 | -1.6463450 | 5 | SCUBE2;HHAT | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0106579 | 0.0694445 | 0.3807304 | -0.7372856 | -1.6473079 | 7 | ESR1;DLL1;DLL3;EGF;ESR2;DLL4 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION | 0.0063754 | 0.0480726 | 0.4070179 | -0.7736140 | -1.6555795 | 6 | PTK2;BMI1;TP53;MDM2 | significant |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 0.0124674 | 0.0779524 | 0.3807304 | -0.5433145 | -1.6614645 | 21 | CACNA2D2;CACNG1;CACNG4;CACNG6;CACNB2;TRDN;CACNA2D3;CASQ2;CACNG2;CACNA2D1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 0.0019953 | 0.0202474 | 0.4317077 | -0.4072656 | -1.6748833 | 91 | IGF1R;KITLG;KIT;FGFR2;ERBB3;FGFR3;PDGFA;RET;ERBB4;PDGFD;EFNA5;NTRK2;IGF2;NGFR;FGFR1;INSR;NTF4;KRAS;AREG;FGF5;FGF10;FGF7;FGF8;EGF;VEGFA;PDGFRB;FGF20;FLT1;BDNF;ERBB2;FGF2;IGF1;ANGPT1;FLT4;TEK;TGFA;EFNA3;FGF18;FGF17;FGF19;FGF3;FGF23;NTF3 | significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION | 0.0084131 | 0.0591783 | 0.3807304 | -0.7207366 | -1.6847494 | 8 | DLL1;DLL3;NEURL1B;JAG1;DLL4;MIB1;MIB2;JAG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 0.0033547 | 0.0305372 | 0.4317077 | -0.6857208 | -1.7575065 | 11 | KITLG;KIT | significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY | 0.0029808 | 0.0280273 | 0.4317077 | -0.6628251 | -1.7685444 | 13 | HEY1;DLL1;DLL3;NOTCH4;JAG1;DLL4;HES1;JAG2;NOTCH3;RBPJL | significant |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 0.0009227 | 0.0105412 | 0.4772708 | -0.4728724 | -1.7691336 | 54 | FGFR2;ITPR2;ERBB3;FGFR3;PDGFA;MST1;RET;ERBB4;NTRK3;PDGFD;NTRK2;FGFR1;FGF5;FGF10;FGF7;FGF8;EGF;VEGFA;PDGFRB;FGF20;FLT1;ERBB2;FGF2;FLT4;FGF18;FGF17;FGF19;FGF3;FGF23 | significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4 | 0.0045771 | 0.0382867 | 0.4070179 | -0.6453183 | -1.7699301 | 14 | LRP6;FZD9;FZD4;LRP4;FZD6;FZD3 | significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 0.0029884 | 0.0280273 | 0.4317077 | -0.5519486 | -1.7789839 | 25 | CACNA1H;CACNA2D2;CACNG1;CACNG4;CACNA1D;CACNG6;CACNB2;CACNA1C;CACNA2D3;CACNA1I;CACNG2;CACNA2D1 | significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 0.0003137 | 0.0046239 | 0.4984931 | -0.4402473 | -1.7960031 | 88 | IGF1R;KITLG;KIT;FGFR2;ERBB3;FGFR3;PDGFA;ERBB4;PDGFD;EFNA5;NTRK2;IGF2;NGFR;FGFR1;INSR;NTF4;KRAS;AREG;FGF5;FGF10;FGF7;FGF8;EGF;VEGFA;PDGFRB;FGF20;FLT1;BDNF;ERBB2;PIK3R2;FGF2;IGF1;ANGPT1;FLT4;TEK;TGFA;EFNA3;FGF18;FGF17;FGF19;FGF3;FGF23;NTF3 | significant |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 0.0016646 | 0.0174641 | 0.4550599 | -0.6041535 | -1.8475112 | 21 | CACNA2D2;CACNG1;RYR2;CACNG4;CACNG6;CACNB2;TRDN;CACNA1C;CACNA2D3;CASQ2;CACNG2;CACNA2D1 | significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0011095 | 0.0120484 | 0.4550599 | -0.7293461 | -1.8693183 | 11 | TFF1;ESR1;PGR;BCL2 | significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 0.0000880 | 0.0015557 | 0.5384341 | -0.4651827 | -1.8726034 | 82 | IGF1R;KITLG;KIT;FGFR2;ERBB3;FGFR3;PDGFA;ERBB4;PDGFD;EFNA5;NTRK2;IGF2;NGFR;FGFR1;INSR;NTF4;AREG;FGF5;FGF10;FGF7;FGF8;EGF;VEGFA;PDGFRB;FGF20;FLT1;BDNF;ERBB2;PIK3R2;FGF2;IGF1;ANGPT1;FLT4;TEK;TGFA;EFNA3;FGF18;FGF17;FGF19;FGF3;FGF23;NTF3 | significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 0.0006892 | 0.0082040 | 0.4772708 | -0.5891203 | -1.8987919 | 25 | IGF1R;KIT;FGFR2;ERBB3;FGFR3;ERBB4;NTRK2;NGFR;FGFR1;INSR | significant |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 0.0005824 | 0.0075104 | 0.4772708 | -0.6759522 | -1.9225233 | 16 | HEY1;HEY2;HES5;HEYL;DLL1;DLL3;NOTCH4;JAG1;DLL4;ERBB2;HES1;JAG2;FLT4;RBPJL | significant |
| | | 0% | |== | 3% | |==== | 6% | |====== | 9% | |======== | 12% | |=========== | 15% | |============= | 18% | |=============== | 21% | |================= | 24% | |=================== | 27% | |===================== | 30% | |======================= | 33% | |========================= | 36% | |============================ | 39% | |============================== | 42% | |================================ | 45% | |================================== | 48% | |==================================== | 52% | |====================================== | 55% | |======================================== | 58% | |========================================== | 61% | |============================================= | 64% | |=============================================== | 67% | |================================================= | 70% | |=================================================== | 73% | |===================================================== | 76% | |======================================================= | 79% | |========================================================= | 82% | |=========================================================== | 85% | |============================================================== | 88% | |================================================================ | 91% | |================================================================== | 94% | |==================================================================== | 97% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 0.0000000 | 0.0000107 | 0.7195128 | 0.7299846 | 2.3044790 | 44 | IL2RB;STAT1;IL12RB2;IFNG;IL2RG;PIM1;IL7R;IL2RA;IL15;IL15RA;IL23A;JAK3;IL6;IFNGR1;IL6R;IL3RA;STAT5A;IFNAR2;IL7;JAK2;STAT4;STAT2;IL4R;IFNGR2 | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES | 0.0000000 | 0.0000013 | 0.7749390 | 0.9426258 | 2.2649202 | 13 | HLA-DRA;HLA-DPA1;HLA-DRB1;HLA-DRB5;HLA-DQA2;CD74;HLA-DMA;HLA-DPB1;HLA-DQA1;HLA-DOB;HLA-DQB1;HLA-DMB;HLA-DOA | significant |
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0000031 | 0.0003846 | 0.6272567 | 0.7927872 | 2.2104485 | 23 | IL21R;IL2RB;STAT1;IL2RG;IL7R;IL2RA;IL15;IL15RA;JAK3;STAT5A;IL7;IL4R | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION | 0.0000001 | 0.0000201 | 0.7049757 | 0.9175572 | 2.2046860 | 13 | HLA-DRA;HLA-DPA1;HLA-DRB1;HLA-DRB5;HLA-DQA2;HLA-DMA;HLA-DPB1;HLA-DQA1;HLA-DOB;HLA-DQB1;HLA-DMB;HLA-DOA | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 0.0000080 | 0.0008208 | 0.5933255 | 0.7677257 | 2.1519538 | 24 | CCNE1;CDC45;CDT1;MCM2;MCM5;MCM6;MCM3;MCM4;CCNA2;CCNE2;TICRR;ORC6;MCM7;CDC7;CDC6;ORC3 | significant |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 0.0000950 | 0.0053448 | 0.5384341 | 0.6958115 | 2.0679940 | 30 | CDC45;MCM10;MCM2;MCM5;MCM6;MCM3;MCM4;RFC4;MCM7;PCNA;WDHD1;PRIM2;RFC2;GINS1;GINS2;POLA2;RFC3;RPA2;RPA1;POLE2;GINS3;GINS4;POLE3 | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 0.0000624 | 0.0038600 | 0.5384341 | 0.7776543 | 2.0320431 | 18 | CDC45;MCM2;MCM5;MCM6;MCM3;MCM4;PIF1;MCM7;VCP;GINS1;GINS2;LRR1;CUL2;GINS3;GINS4 | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0002114 | 0.0093481 | 0.5188481 | 0.8322507 | 1.9680718 | 12 | TAP1;HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;B2M;HLA-G;TAP2;CALR;TAPBP | significant |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0005522 | 0.0201060 | 0.4772708 | 0.7385714 | 1.9489038 | 19 | CD3D;LCK;CD3G;CD247;PLCG2;ZAP70;LCP2;VAV1;LAT;FYN;ITPR3 | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000127 | 0.0011189 | 0.5933255 | 0.9402509 | 1.9421088 | 7 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;B2M;HLA-G | significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0004931 | 0.0201060 | 0.4772708 | 0.8069369 | 1.9388901 | 13 | MMP1;CCL2;MMP3;ACE2;CYBB;IL1B;TNF;IL6 | significant |
| KEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION | 0.0000321 | 0.0022092 | 0.5573322 | 0.9201977 | 1.9340094 | 8 | MCM2;MCM5;MCM6;MCM3;MCM4;PIF1;MCM7 | significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0007835 | 0.0226410 | 0.4772708 | 0.7660215 | 1.9312921 | 16 | CYBB;NCF1;NCF2;RAC2;NCF4;FYN;CYBA;PIK3CD | significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000263 | 0.0020344 | 0.5756103 | 0.9322385 | 1.9255592 | 7 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;HLA-G | significant |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 0.0006451 | 0.0210171 | 0.4772708 | 0.7709981 | 1.9192004 | 15 | CDC45;MCM2;MCM5;MCM6;MCM3;MCM4;MCM7;VCP;GINS1;GINS2;GINS3;GINS4 | significant |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 0.0005223 | 0.0201060 | 0.4772708 | 0.6731846 | 1.9167064 | 26 | STAT1;IFNG;JAK3;IFNGR1;STAT5A;IFNAR2;JAK2;STAT4;STAT2;IFNGR2 | significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 0.0008615 | 0.0231857 | 0.4772708 | 0.7946764 | 1.9094308 | 13 | CCL5;CCL4;CCL2;CCL3;CX3CL1 | significant |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 0.0010882 | 0.0259082 | 0.4550599 | 0.6584822 | 1.9078497 | 27 | CDC45;CDT1;MCM2;MCM5;MCM6;MCM3;MCM4;TICRR;ORC6;MCM7;CDC6;ORC3;GINS1;GINS2;ORC1;POLE2;GINS3;GINS4;POLE3 | significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0001559 | 0.0080403 | 0.5188481 | 0.9401973 | 1.8743655 | 6 | HLA-F;HLA-E;HLA-A;HLA-C;HLA-B;HLA-G | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0008047 | 0.0226410 | 0.4772708 | 0.6140080 | 1.8587529 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;APP;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0005997 | 0.0206231 | 0.4772708 | 0.5950252 | 1.8495552 | 39 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;VCP;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0009094 | 0.0234559 | 0.4772708 | 0.6106846 | 1.8486923 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PRNP;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX | 0.0014007 | 0.0298971 | 0.4550599 | 0.8025874 | 1.8372135 | 11 | NUF2;NDC80;SPAG5;AURKA;SPC25;AURKB;CENPE;PPP1CB | significant |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0018965 | 0.0378688 | 0.4550599 | 0.5898594 | 1.8223631 | 38 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0010535 | 0.0259082 | 0.4550599 | 0.5830043 | 1.8121900 | 39 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0007587 | 0.0226410 | 0.4772708 | 0.8738290 | 1.8049130 | 7 | IL2RB;IL2RG;JAK3;STAT5A | significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 0.0042546 | 0.0731559 | 0.4070179 | 0.7158902 | 1.8049010 | 16 | CENPW;NUF2;NDC80;CDCA8;BIRC5;SPC25;INCENP;AURKB;ZWINT;PMF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE | 0.0001914 | 0.0091121 | 0.5188481 | 0.9482385 | 1.8015722 | 5 | C1QB;C1QA;C1QC;C1S;C1R | significant |
| KEGG_MEDICUS_REFERENCE_NON_CANONICAL_INFLAMMASOME_SIGNALING_PATHWAY | 0.0012028 | 0.0270623 | 0.4550599 | 0.8639833 | 1.7845765 | 7 | CASP1;IL1B;CASP5;CASP4;IL18;NLRP3 | significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 0.0059241 | 0.0991080 | 0.4070179 | 0.6930733 | 1.7778660 | 17 | WIPF1;ACTR3;ARPC5L;NCK1;ARPC1B;ACTR2;ACTB;NCK2;WIPF2;ARPC2;ARPC5;WIPF3;ARPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH | 0.0027320 | 0.0512450 | 0.4317077 | 0.8873680 | 1.7690457 | 6 | SERPING1;C1S;PLAU;C1R | non-significant |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0076743 | 0.1131043 | 0.4070179 | 0.6000956 | 1.7680350 | 29 | CYBB;NCF1;NCF2;RAC2;NCF4;FYN;CYBA;CREB3L2;MAPK1;ATF4;PIK3CD | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 0.0080742 | 0.1162315 | 0.3807304 | 0.6516863 | 1.7639139 | 20 | TLR2;TNF;TLR1;IL6;MYD88;TLR4;NFKBIA;NFKB1;MAP3K7;IRAK1;IKBKG;IL12A | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0072531 | 0.1110057 | 0.4070179 | 0.6971414 | 1.7576317 | 16 | STAT1;IFNG;IFNGR1;JAK2;IFNGR2;IL27 | non-significant |
| KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE | 0.0084870 | 0.1167438 | 0.3807304 | 0.7416345 | 1.7537863 | 12 | TTK;NUF2;NDC80;SKA3;SPC25;AURKB;PPP1CB;SKA1;SKA2;PPP1CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0036738 | 0.0668843 | 0.4317077 | 0.5778654 | 1.7493405 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0021130 | 0.0408730 | 0.4317077 | 0.5581768 | 1.7396004 | 40 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;DERL1;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | significant |
| KEGG_MEDICUS_REFERENCE_RECRUITMENT_AND_FORMATION_OF_THE_MCC | 0.0073526 | 0.1110057 | 0.4070179 | 0.7889877 | 1.7267857 | 9 | TTK;CDC20;BUB1;NDC80;AURKB;MAD2L1;BUB1B | non-significant |
| KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY | 0.0042468 | 0.0731559 | 0.4070179 | 0.8306422 | 1.7157098 | 7 | FASLG;MAP3K5;FAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00482 | 0.0100864 | 0.1328406 | 0.3807304 | 0.7796930 | 1.7064431 | 9 | CCNE1;E2F3;CCNA2;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0155778 | 0.1691698 | 0.3807304 | 0.5757728 | 1.6963736 | 29 | CYTH1;NCKAP1L;ACTR3;WASF3;ARPC5L;CYTH4;ARPC1B;PIK3CD;ACTR2;ACTB;ABI1;ARPC2;ARPC5;WASF1;ARPC4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0072292 | 0.1110057 | 0.4070179 | 0.5583426 | 1.6902401 | 35 | PSMD3;PSMB3;PSMB2;PSMD11;PSMD2;PSMA3;PSMB4;PSMB5;PSMA4;PSMC2;PSMD7;PSMD14;ADRM1;PSMA7;PSMC4;PSMB7;PSMD12;PSMB6;PSMD8;PSMA5;PSMB1;PSMC1;PSMA6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_P27_CELL_CYCLE_G1_S | 0.0070015 | 0.1110057 | 0.4070179 | 0.8178697 | 1.6893279 | 7 | CCNE1;E2F3;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00536 | 0.0108951 | 0.1405009 | 0.3807304 | 0.7377999 | 1.6889075 | 11 | CDKN2A;CCNE1;E2F3;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 0.0162207 | 0.1701803 | 0.3524879 | 0.6374660 | 1.6821122 | 19 | PLCG2;PRKCB;CXCR4;MAPK1;PLCB2;PLCB4;PRKCA;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0113561 | 0.1434576 | 0.3807304 | 0.6747887 | 1.6797121 | 15 | FASLG;TNFSF10;CASP10;BID;BAK1;FAS;CASP3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY | 0.0210233 | 0.2016400 | 0.3524879 | 0.6841903 | 1.6727117 | 14 | ACTR3;ARPC5L;ARPC1B;ACTR2;ACTB;ABI1;ARPC2;ARPC5;ARPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS | 0.0176838 | 0.1765532 | 0.3524879 | 0.7067724 | 1.6713457 | 12 | IDO1;TDO2;KYNU;KMO;QPRT | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0138042 | 0.1612229 | 0.3807304 | 0.5621585 | 1.6707691 | 30 | CYTH1;PIK3CG;ACTR3;WASF3;ARPC5L;CYTH4;ARPC1B;PIK3CD;ACTR2;ACTB;ABI1;ARPC2;ARPC5;WASF1;ARPC4;PIK3CA;PIK3C2B;ACTG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0149664 | 0.1684399 | 0.3807304 | 0.7430294 | 1.6639715 | 10 | IL12RB2;IL23A;JAK2;STAT4;IL12RB1;STAT3;IL12A | non-significant |
| KEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT | 0.0126880 | 0.1517126 | 0.3807304 | 0.8013498 | 1.6552057 | 7 | CP;TFRC;STEAP3;SLC11A2;TF | non-significant |
| KEGG_MEDICUS_REFERENCE_II_BLOOD_GROUP_ANTIGEN_BIOSYNTHESIS | 0.0142259 | 0.1630709 | 0.3807304 | 0.7976795 | 1.6476246 | 7 | B3GNT3;B4GALT3;GCNT2;B3GNT4;B4GALT1;B4GALT4 | non-significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 0.0251402 | 0.2255332 | 0.3524879 | 0.5567593 | 1.6403550 | 29 | ALYREF;NUP93;NUP155;NUP205;NXT1;NCBP1;NUP210;NUP88;SRSF3;NUP160;NUP85;NUP214;SEH1L;DDX19B;NUP62;NDC1;NXT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00498 | 0.0171910 | 0.1744467 | 0.3524879 | 0.7774105 | 1.6339089 | 8 | CCNE1;E2F3;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0171910 | 0.1744467 | 0.3524879 | 0.7773046 | 1.6336863 | 8 | PLCG2;SYK;LYN;BTK;ITPR3;BLNK | non-significant |
| KEGG_MEDICUS_REFERENCE_INACTIVATION_OF_CONDENSIN_I | 0.0279940 | 0.2406705 | 0.3524879 | 0.8177305 | 1.6302173 | 6 | NCAPD2;SMC4;NCAPG;NCAPH;CSNK2A2 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 0.0155139 | 0.1691698 | 0.3807304 | 0.5926888 | 1.6295780 | 21 | WIPF1;ACTR3;ARPC5L;NCK1;ARPC1B;ACTR2;ACTB;NCK2;WIPF2;ARPC2;ARPC5;WIPF3;ARPC4;SRC;EGFR | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00497 | 0.0256156 | 0.2265147 | 0.3524879 | 0.7419909 | 1.6239281 | 9 | CCNE1;E2F3;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 0.0127448 | 0.1517126 | 0.3807304 | 0.5696363 | 1.6218815 | 26 | CCL5;CCR5;PRKCB;GNB4;GNGT2;PLCB2;GNG4;PLCB4;GNG7 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY | 0.0190101 | 0.1867820 | 0.3524879 | 0.7845609 | 1.6205277 | 7 | CD40;RELB;CD40LG;TRAF2;NFKB2;TRAF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0353577 | 0.2842392 | 0.3217759 | 0.8098788 | 1.6145642 | 6 | FUT3;FUT4;FUT7;ST3GAL6;FUT5 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.0211738 | 0.2016400 | 0.3524879 | 0.7803172 | 1.6117624 | 7 | STAT1;ERBB2;VEGFA;EGFR;STAT3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_REL_TO_TRANSCRIPTION | 0.0221469 | 0.2046108 | 0.3524879 | 0.7641875 | 1.6061177 | 8 | BIRC3;TRAF1;CD40;BCL2A1;CCND2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.0299531 | 0.2539861 | 0.3524879 | 0.6248342 | 1.6028198 | 17 | PLCG2;SYK;LYN;BTK;BLNK | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCNE_TO_CELL_CYCLE_G1_S | 0.0402769 | 0.3136029 | 0.3217759 | 0.8012080 | 1.5972782 | 6 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MODIFYING_OF_CONDENSIN_II_SUBUNITS | 0.0408918 | 0.3136029 | 0.3217759 | 0.7981871 | 1.5912558 | 6 | CDK1;AURKB;PLK1;NCAPG2;NCAPD3;NCAPH2 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN | 0.0272158 | 0.2372758 | 0.3524879 | 0.7097914 | 1.5895368 | 10 | FCN1;FCN3;FGG | non-significant |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0219825 | 0.2046108 | 0.3524879 | 0.5609857 | 1.5818087 | 25 | CYTH1;ACTR3;WASF3;ARPC5L;CYTH4;ARPC1B;ACTR2;ACTB;ABI1;ARPC2;ARPC5;WASF1;ARPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 0.0425568 | 0.3136029 | 0.3217759 | 0.5831469 | 1.5783987 | 20 | DNMT3B;TOP2A;KIF4A;NCAPD2;SMC4;NCAPG;NCAPG2;NCAPH;PPP2R5D;PPP2R5C;NCAPD3;SMC2;NCAPH2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00264 | 0.0343743 | 0.2799697 | 0.3217759 | 0.6891123 | 1.5774560 | 11 | CCNE1;E2F3;CCNA2;E2F2;CCNE2;E2F1;SKP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY | 0.0501154 | 0.3433963 | 0.3217759 | 0.6447504 | 1.5762888 | 14 | FANCE;FANCA;UBE2T;FANCC;FANCG;FANCD2;FANCI;FANCB;FANCL | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 0.0418329 | 0.3136029 | 0.3217759 | 0.5694410 | 1.5710094 | 22 | TUBB3;KIF2C;TUBB;AURKA;TUBA4A;AURKB;TUBB6;TUBB2A;TUBB4A;TUBA1C;KIF18B;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 0.0527358 | 0.3500680 | 0.3217759 | 0.6415370 | 1.5684327 | 14 | CD19;SYK;LYN;CR2;PIK3CD | non-significant |
| KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.0338592 | 0.2794514 | 0.3217759 | 0.7556669 | 1.5608466 | 7 | C1QB;C1QA;C1QC;C2;C1S;C1R | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 0.0481481 | 0.3386780 | 0.3217759 | 0.5765744 | 1.5606090 | 20 | ACTR3;WASF3;ARPC5L;ARPC1B;ACTR2;ACTB;ABI1;ARPC2;ARPC5;WASF1;ARPC4 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_REPRESSION | 0.0538048 | 0.3500680 | 0.3217759 | 0.7806147 | 1.5562236 | 6 | MYCN;MAX | non-significant |
| KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY | 0.0550346 | 0.3512004 | 0.3217759 | 0.7791292 | 1.5532622 | 6 | CASP1;IL1B;IL18;NLRP3;IL33 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 0.0338199 | 0.2794514 | 0.3217759 | 0.6218404 | 1.5479109 | 15 | CCNE1;E2F3;E2F2;CCNE2;E2F1;CUL1;CKS1B;SKP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 0.0423646 | 0.3136029 | 0.3217759 | 0.6026910 | 1.5460181 | 17 | TNF;IL6;MYD88;NFKBIA;NFKB1;MAP3K7;IRAK1;IKBKG;IL12A | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE | 0.0605688 | 0.3542628 | 0.3217759 | 0.7721483 | 1.5393452 | 6 | FCN1;FCN3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 0.0461869 | 0.3286174 | 0.3217759 | 0.5982440 | 1.5346106 | 17 | CCR5;PLCG2;CXCR4;NFATC3;CALM3;PLCG1;NFATC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_AHR_SIGNALING_PATHWAY | 0.0413998 | 0.3136029 | 0.3217759 | 0.7263873 | 1.5266718 | 8 | IL6;VEGFA;PTGS2;CYP1B1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 0.0643069 | 0.3685739 | 0.2878051 | 0.5621153 | 1.5214729 | 20 | PTPN7;DUSP6;DUSP2;MAPK1;DUSP10;DUSP4;DUSP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_INNER_KINETOCHORE | 0.0757094 | 0.3992852 | 0.2878051 | 0.6199022 | 1.5155398 | 14 | CENPW;CENPA;CENPO;CENPN;CENPM | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN | 0.0538302 | 0.3500680 | 0.2820134 | 0.7160833 | 1.5050156 | 8 | FCN1;FCN3 | non-significant |
| KEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION | 0.0542917 | 0.3500680 | 0.3217759 | 0.6572295 | 1.5044727 | 11 | GZMB;HDAC2;CSF2;ELANE | non-significant |
| KEGG_MEDICUS_REFERENCE_P27_CELL_CYCLE_G1_S | 0.0928259 | 0.4336151 | 0.2878051 | 0.6111256 | 1.4940828 | 14 | CCNE1;E2F3;CCNA2;E2F2;CCNE2;E2F1;CUL1;SKP2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY | 0.0600727 | 0.3542628 | 0.3217759 | 0.6214724 | 1.4932600 | 13 | ACTR3;ARPC5L;ARPC1B;ACTR2;ACTB;ARPC2;ARPC5;ARPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY | 0.0600414 | 0.3542628 | 0.2663507 | 0.7080865 | 1.4882085 | 8 | PLCG2;PRKCB;PRKCA;EGFR;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 0.0568421 | 0.3542628 | 0.2765006 | 0.5625191 | 1.4843461 | 19 | TUBB3;TUBB;TUBA4A;CENPF;CENPE;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBB2B;BUB1B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 0.0594262 | 0.3542628 | 0.2663507 | 0.4982898 | 1.4809475 | 30 | CCL4;CCL2;CCL3;GNB4;PIK3CG;GNGT2;GNG4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY | 0.0705966 | 0.3867193 | 0.2878051 | 0.6157455 | 1.4794996 | 13 | ACTR3;ARPC5L;ARPC1B;ACTR2;ACTB;ARPC2;ARPC5;ARPC4;SRC;ACTG1 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_CDKN1B_TO_P27_CELL_CYCLE_G1_S | 0.0662526 | 0.3728214 | 0.2529611 | 0.7021367 | 1.4757035 | 8 | CCNE1;E2F3;E2F2;CCNE2;E2F1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S | 0.0879346 | 0.4219496 | 0.2165428 | 0.7335798 | 1.4624556 | 6 | E2F3;E2F2;CDK6;E2F1;CDK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0800000 | 0.4090180 | 0.2311267 | 0.7658450 | 1.4550400 | 5 | FUT3;FUT4;FUT5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0589474 | 0.3542628 | 0.2712886 | 0.5509821 | 1.4539029 | 19 | STAT1;IFNAR2;STAT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 0.0720339 | 0.3877303 | 0.2450418 | 0.5619806 | 1.4415880 | 17 | IL1B;ZFP36;MYD88;MAP2K3;MAP3K7;IL1R1;IRAK1;MAPK14;IL1RAP;MAP2K6 | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 0.0774059 | 0.3992852 | 0.2343926 | 0.5224322 | 1.4413184 | 22 | TUBB3;TUBB;AURKA;TUBA4A;TUBB6;TACC3;TUBB2A;TUBB4A;TUBA1C;TUBB2B;CLTA;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0910973 | 0.4304522 | 0.2139279 | 0.6832342 | 1.4359755 | 8 | MMP9;CYBB;VCAM1;IL6;NFKB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY | 0.0765957 | 0.3992852 | 0.2377938 | 0.6406071 | 1.4346027 | 10 | PRKCB;PLCB2;PLCB4;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY | 0.0931677 | 0.4336151 | 0.2114002 | 0.6802807 | 1.4297682 | 8 | FCGR3A;RAC2;FCGR3B;FCGR2A | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 0.0715789 | 0.3877303 | 0.2450418 | 0.5380891 | 1.4198817 | 19 | TUBB3;TUBB;TUBA4A;TUBB6;PLK1;KIF2A;TUBB2A;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 0.0866808 | 0.4219496 | 0.2220560 | 0.5414989 | 1.4149591 | 18 | STAT1;IFNAR2;STAT2;EIF2AK2;IRF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS | 0.1031579 | 0.4603744 | 0.2020717 | 0.7442514 | 1.4140140 | 5 | B3GNT5;FUT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY | 0.1087866 | 0.4809922 | 0.1957890 | 0.5896365 | 1.3943478 | 12 | CCL2;BIRC3;NFKBIA;NFKB1;TRAF2;TNFRSF14;IKBKG | non-significant |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0903361 | 0.4301390 | 0.2165428 | 0.4800453 | 1.3908565 | 27 | STAT1;IL27RA;OSM;IL6;IL6R;JAK2;IL4R;IL27 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.1177686 | 0.4951717 | 0.1864326 | 0.6706127 | 1.3851654 | 7 | STAT1;STAT5A;EGFR;STAT3;STAT5B | non-significant |
| KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M | 0.1170213 | 0.4951717 | 0.1900233 | 0.6180130 | 1.3840043 | 10 | CDC25B;CHEK1;CDK1;CCNB2;CHEK2;CDC25C;CCNB1;ATM;ATR | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 0.1016949 | 0.4594829 | 0.2042948 | 0.5362592 | 1.3756078 | 17 | TNF;IL6;MAPK1;APP;NFKB1;NRAS;RAF1;NOS2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.1150628 | 0.4951717 | 0.1900233 | 0.5806313 | 1.3730526 | 12 | CCR5;CXCR4;PIK3CD | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_CELL_CYCLE_G1_S | 0.1411043 | 0.5410985 | 0.1682382 | 0.6794008 | 1.3544449 | 6 | E2F3;E2F2;E2F1;RBL1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA2_TO_RBP_JK_MEDIATED_TRANSCRIPTION | 0.1446281 | 0.5492319 | 0.1669338 | 0.6548450 | 1.3525968 | 7 | RUNX3;CR2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY | 0.1234310 | 0.5051602 | 0.1830239 | 0.5712405 | 1.3508457 | 12 | PRKCB;MAPK1;PRKCA;RAF1;FOS;JUN | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION | 0.1554622 | 0.5573229 | 0.1619789 | 0.6167544 | 1.3498343 | 9 | IDH2;IDH1;ACO2;IDH3G;ACLY;IDH3B | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 0.1291759 | 0.5162186 | 0.1847065 | 0.5400458 | 1.3443044 | 15 | PRKD3;NFKBIA;NFKB1;PTPRJ;PRKD2;SRC;IKBKG | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.1511387 | 0.5567088 | 0.1631801 | 0.6390077 | 1.3430232 | 8 | BID;BAK1;CASP3;BAX;CASP8;CYCS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.1155462 | 0.4951717 | 0.1900233 | 0.4714402 | 1.3422952 | 26 | CCR5;CXCR4;RAC2;GNB4;GNGT2;GNG4;GNG7;CFL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOD_NFKB_SIGNALING_PATHWAY | 0.1575630 | 0.5573229 | 0.1608014 | 0.6130826 | 1.3417983 | 9 | NOD2;RIPK2;NFKBIA;NFKB1;NOD1;IKBKG | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 0.1183932 | 0.4951717 | 0.1882041 | 0.4746441 | 1.3383516 | 25 | EZH2;JARID2;HDAC2;TFDP1;WDR5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY | 0.1317992 | 0.5163524 | 0.1766943 | 0.5644909 | 1.3348844 | 12 | PRKCB;PLCB2;PLCB4;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.1281513 | 0.5162186 | 0.1797823 | 0.4647271 | 1.3231816 | 26 | TLR2;MAPK1;MYD88;TLR4;MAP2K3;MAP3K7;MAPK13;IRAK1;FOS;JUN;MAPK14 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.1331967 | 0.5185457 | 0.1737478 | 0.4422250 | 1.3210556 | 31 | CCL2;CCR2;GNB4;GNGT2;GNG4;PIK3CD;NFKBIA;NFKB1;GNG7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY | 0.1416122 | 0.5410985 | 0.1737478 | 0.5390512 | 1.3178750 | 14 | ACTR3;ARPC5L;ARPC1B;ACTR2;ACTB;ARPC2;ARPC5;ARPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 0.1300813 | 0.5162186 | 0.1752040 | 0.4362134 | 1.3151759 | 33 | CLDN1;ACTR3;ARPC5L;CLDN10;ARPC1B;ACTR2;CLDN23;CLDN4;CLDN14;ACTB;CLDN6;ARPC2;ARPC5;ARPC4 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.1590414 | 0.5593558 | 0.1631801 | 0.5326050 | 1.3021154 | 14 | PLCG2;CAMK1D;PDGFRA;CAMK2D;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.1575492 | 0.5573229 | 0.1644058 | 0.5130470 | 1.2934932 | 16 | CDC20;PTTG2;PTTG1;CDC16 | non-significant |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 0.1619256 | 0.5599550 | 0.1619789 | 0.5117919 | 1.2903288 | 16 | TNF;IL6;MAPK1;NFKB1;NRAS;RAF1;NOS2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.1619256 | 0.5599550 | 0.1619789 | 0.5117909 | 1.2903262 | 16 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.1540041 | 0.5573229 | 0.1608014 | 0.4685862 | 1.2883621 | 21 | PLCG2;CXCR4;PLCB2;PLCB4;NFATC3;CALM3;PLCG1;NFATC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.1495902 | 0.5567088 | 0.1631801 | 0.4306900 | 1.2865974 | 31 | PRKCB;CXCR4;GNB4;GNGT2;PLCB2;GNG4;PLCB4;PTK2B;GNG7;PRKCA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.1816239 | 0.6067892 | 0.1501698 | 0.5615237 | 1.2853912 | 11 | BID;BAK1;FAS;CASP3;APP;BAX;CASP8;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.1528926 | 0.5567088 | 0.1619789 | 0.4748326 | 1.2852254 | 20 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;ARHGEF2;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.0857143 | 0.4219496 | 0.2192503 | 0.9526958 | 1.2822368 | 1 | CCND2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 0.2205882 | 0.6827206 | 0.1335550 | 0.5831164 | 1.2762138 | 9 | PDCD1;CD274;PIK3CD;PTPN6;PDCD1LG2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR2_TO_CELL_SURFACE_MOLECULE_ENDOCYTOSIS | 0.2229039 | 0.6864552 | 0.1307771 | 0.6384864 | 1.2728784 | 6 | ICAM1;IFNGR1;CLEC2B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.1822034 | 0.6067892 | 0.1492075 | 0.4891011 | 1.2546383 | 17 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_PATHOGEN_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_II | 0.2413088 | 0.6967974 | 0.1250334 | 0.6238793 | 1.2437579 | 6 | SDHA;SDHC;GSTO1;SDHD | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 0.2093541 | 0.6749490 | 0.1420566 | 0.4991840 | 1.2425895 | 15 | CDCA5;CDK1;AURKB;PLK1;PPP2R5D;PPP2R5C | non-significant |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.1991786 | 0.6455057 | 0.1395997 | 0.4501843 | 1.2377667 | 21 | CDC20;PTTG2;PTTG1;MAD2L1;MAD2L2;BUB1B;CDC16 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS | 0.2525880 | 0.7042881 | 0.1226792 | 0.5872855 | 1.2343171 | 8 | CSGALNACT1;CHPF2;CHST3;CHPF | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR | 0.2453988 | 0.6967974 | 0.1238422 | 0.6188363 | 1.2337043 | 6 | CFH;CFHR3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_E2_TO_NOD_NFKB_SIGNALING_PATHWAY | 0.2668067 | 0.7221520 | 0.1198878 | 0.5633421 | 1.2329357 | 9 | RIPK2;NFKBIA;NFKB1;NOD1;IKBKG | non-significant |
| KEGG_MEDICUS_VARIANT_DAB1_OVEREXPRESSION_TO_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.2689076 | 0.7221520 | 0.1193484 | 0.5617109 | 1.2293655 | 9 | VLDLR;PIK3CD;DAB1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 0.2275711 | 0.6926151 | 0.1342735 | 0.4861864 | 1.2257723 | 16 | ST6GAL1;MGAT1;B4GALT3;MAN1A1;MOGS;B4GALT1;GANAB | non-significant |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 0.2156057 | 0.6764697 | 0.1335550 | 0.4448692 | 1.2231529 | 21 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_ | 0.2739130 | 0.7276917 | 0.1204334 | 0.7343072 | 1.2221984 | 3 | AMY1C;GAA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 0.2446809 | 0.6967974 | 0.1268757 | 0.5449659 | 1.2204197 | 10 | BIRC5;PIK3CD;NFKB1;PIK3CA;RELA;AKT1;MTOR | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.2483660 | 0.7020026 | 0.1275053 | 0.4977582 | 1.2169217 | 14 | PLCG2;CAMK1D;CAMK2D;EGFR;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS | 0.2510638 | 0.7032059 | 0.1250334 | 0.5410677 | 1.2116899 | 10 | HSD17B2;SRD5A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 0.2151899 | 0.6764697 | 0.1357409 | 0.4312124 | 1.2086988 | 24 | TNF;CREB3L2;ATF4;TRADD;RPS6KA4;MAP2K3;MAP3K7;CREB5;TRAF2;CREB3L1;TNFRSF1A;RIPK1;MAPK14 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 0.2357895 | 0.6950175 | 0.1287887 | 0.4569279 | 1.2057176 | 19 | IL1B;MYD88;MAP3K7;IL1R1;IRAK1;FOS;JUN;IL1RAP | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 0.2309322 | 0.6926151 | 0.1307771 | 0.4699251 | 1.2054481 | 17 | TLR8;IRF5;MYD88;TLR9;IRAK1;TLR7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M | 0.2787234 | 0.7341693 | 0.1177658 | 0.5357163 | 1.1997058 | 10 | CHEK1;CDK1;CCNB2;CDC25C;CCNB1;CUL4A;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M | 0.2706612 | 0.7221520 | 0.1177658 | 0.5787422 | 1.1954048 | 7 | CHEK1;CDK1;CCNB2;WEE1;CCNB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY | 0.2924335 | 0.7532323 | 0.1119183 | 0.5954898 | 1.1871609 | 6 | MAP3K5;APP | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS | 0.2944785 | 0.7532323 | 0.1114627 | 0.5949464 | 1.1860777 | 6 | B3GNT5;B4GALT3;B4GALT1;B4GALT4 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 0.2157676 | 0.6764697 | 0.1342735 | 0.4036940 | 1.1816462 | 28 | WNT6;SFRP1;WNT10A;WNT2;TRABD2A;WNT5B | non-significant |
| KEGG_MEDICUS_VARIANT_TMPRSS2_ERG_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.2830579 | 0.7361883 | 0.1147507 | 0.5712401 | 1.1799091 | 7 | MMP9;MMP3;PLAU;IL1R2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.3013100 | 0.7581397 | 0.1142665 | 0.4883780 | 1.1734638 | 13 | PRKCB;ITPR3;PLCB2;PLCB4;PRKCA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 0.2566735 | 0.7061373 | 0.1209851 | 0.4262531 | 1.1719687 | 21 | CHRM1;ITPR3;PLCB2;PLCB4;SLC25A5;APP | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY | 0.3119658 | 0.7724274 | 0.1105647 | 0.5110007 | 1.1697383 | 11 | TRADD;NFKBIA;NFKB1;MAP3K7;IKBKG | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.3200837 | 0.7865837 | 0.1075544 | 0.4924704 | 1.1645734 | 12 | ERBB2;PIK3CD;EGFR;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.2694878 | 0.7221520 | 0.1232572 | 0.4677570 | 1.1643601 | 15 | PLCG2;CAMK1D;CAMK2D;EGFR;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 0.2844639 | 0.7367496 | 0.1182875 | 0.4588592 | 1.1568750 | 16 | TNF;TRADD;NFKBIA;NFKB1;MAP3K7;TRAF2;IKBKG;TNFRSF1A;RIPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.3234043 | 0.7912539 | 0.1079724 | 0.5163349 | 1.1563022 | 10 | C2;FCN1;FCN3 | non-significant |
| KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S | 0.3297872 | 0.8005423 | 0.1067299 | 0.5149079 | 1.1531066 | 10 | CDKN2A;CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_K15_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.3250518 | 0.7921537 | 0.1059203 | 0.5456390 | 1.1467873 | 8 | NFKBIA;NFKB1;MAP3K7;TRAF2;IKBKG | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.3333333 | 0.8059896 | 0.1035763 | 0.5711640 | 1.1386654 | 6 | TCF7L1;TCF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 0.2815126 | 0.7352587 | 0.1162341 | 0.3963276 | 1.1284330 | 26 | TUBB3;TPX2;TUBB;TUBA4A;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBGCP3;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY | 0.3611111 | 0.8284158 | 0.1013507 | 0.4912756 | 1.1245854 | 11 | PRKCB;PLCB2;PLCB4;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M | 0.3613445 | 0.8284158 | 0.1002791 | 0.5116186 | 1.1197332 | 9 | CHEK1;CDK1;CCNB2;CDKN1A;CCNB1;ATM;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 0.2971311 | 0.7568896 | 0.1110115 | 0.3730446 | 1.1143935 | 31 | TUBB3;TPX2;TUBB;TUBA4A;TUBB6;TUBB2A;HAUS8;TUBB4A;TUBA1C;TUBGCP3;TUBB2B;TUBA1A;HAUS6;TUBA1B;HAUS7 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.3025210 | 0.7581397 | 0.1114627 | 0.3913245 | 1.1141881 | 26 | CXCR4;RAC2;GNB4;GNGT2;GNG4;GNG7;CFL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 0.3389831 | 0.8101564 | 0.1047328 | 0.4318251 | 1.1077143 | 17 | RFC4;FEN1;PCNA;RFC2;LIG1;RFC3;POLD1;POLE2;POLE3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066 | 0.3820961 | 0.8599383 | 0.0992333 | 0.4602424 | 1.1058603 | 13 | CDKN2A;CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 0.3389474 | 0.8101564 | 0.1043440 | 0.4184886 | 1.1042860 | 19 | WNT6;WNT10A;WNT2;WNT5B | non-significant |
| KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY | 0.3512397 | 0.8246180 | 0.1009906 | 0.5294421 | 1.0935744 | 7 | MAP3K5;TRAF2;ERN1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.3451883 | 0.8199569 | 0.1028218 | 0.3959932 | 1.0924907 | 22 | ITPR3;PLCB2;PLCB4;CASP3;SLC25A5;APP | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 0.3457330 | 0.8199569 | 0.1055209 | 0.4327141 | 1.0909581 | 16 | TNF;TRADD;MAP3K7;TRAF2;FOS;TNFRSF1A;RIPK1;JUN | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.3933747 | 0.8703832 | 0.0943564 | 0.5170915 | 1.0867880 | 8 | PRKCB;PTK2B;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.3516949 | 0.8246180 | 0.1024494 | 0.4229262 | 1.0848869 | 17 | PLCG2;CAMK1D;PDGFRA;CAMK2D;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE | 0.4078675 | 0.8703832 | 0.0922597 | 0.5096343 | 1.0711150 | 8 | MRAS;PPP1CB;RAF1;PPP1CA;PPP1CC | non-significant |
| KEGG_MEDICUS_REFERENCE_MEVALONATE_PATHWAY | 0.4079498 | 0.8703832 | 0.0928481 | 0.4528971 | 1.0709922 | 12 | ACAT2;FDPS;IDI1;MVD;HMGCS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION | 0.4151329 | 0.8703832 | 0.0905429 | 0.5324077 | 1.0614013 | 6 | CDCA5;STAG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LIGHT_HVEM_NFKB_SIGNALING_PATHWAY | 0.4234043 | 0.8703832 | 0.0916795 | 0.4732583 | 1.0598347 | 10 | TNFSF14;NFKBIA;NFKB1;TRAF2;TNFRSF14;IKBKG | non-significant |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 0.3987603 | 0.8703832 | 0.0934449 | 0.3910132 | 1.0583521 | 20 | CHRM1;ITPR3;PLCB2;PLCB4;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_RASSF1_TO_RAS_RASSF1_SIGNALING_PATHWAY | 0.4233129 | 0.8703832 | 0.0894367 | 0.5308145 | 1.0582252 | 6 | RASSF5;NRAS;STK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 0.4028926 | 0.8703832 | 0.0928481 | 0.3894817 | 1.0542069 | 20 | EZH2;JARID2;TRIM27 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION | 0.4355828 | 0.8703832 | 0.0878313 | 0.5265623 | 1.0497479 | 6 | MYCN;MAX | non-significant |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 0.3970588 | 0.8703832 | 0.0946646 | 0.3670708 | 1.0451323 | 26 | EXO1;RFC4;PCNA;RFC2;MSH2;MSH6;LIG1;RFC3;RPA2;POLD1;RPA1;POLE2;POLE3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.4558824 | 0.8723536 | 0.0867950 | 0.4737747 | 1.0369076 | 9 | MET;PIK3CD;PIK3CA;AKT1;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY | 0.4235808 | 0.8703832 | 0.0931455 | 0.4304882 | 1.0343675 | 13 | MAPK1;YWHAQ;YWHAH;RAF1;YWHAZ | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 0.4492754 | 0.8703832 | 0.0867950 | 0.4919980 | 1.0340482 | 8 | PIK3CD;PDGFRA;PIK3CA;AKT1;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY | 0.4357298 | 0.8703832 | 0.0913924 | 0.4220333 | 1.0317892 | 14 | SLC7A5;RRAGD | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 0.4372385 | 0.8703832 | 0.0888945 | 0.3735816 | 1.0306603 | 22 | GSTA5;GSTA2;GSTA1;GSTP1;GSTA4;GSTA3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.4421488 | 0.8703832 | 0.0875697 | 0.4979124 | 1.0284489 | 7 | NFKBIA;NFKB1;TRAF2;IKBKG;RELA | non-significant |
| KEGG_MEDICUS_REFERENCE_OKAZAKI_FRAGMENT_MATURATION | 0.4444444 | 0.8703832 | 0.0891647 | 0.4486347 | 1.0269757 | 11 | FEN1;PCNA;RNASEH2A;LIG1;POLD1;RNASEH2B;DNA2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.4098361 | 0.8703832 | 0.0913924 | 0.3455027 | 1.0268551 | 30 | IL6;GNB4;GNGT2;GNG4;PIK3CD;NFKBIA;NFKB1;GNG7 | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS | 0.4444444 | 0.8703832 | 0.0891647 | 0.4485791 | 1.0268483 | 11 | ACSL1;ACSL5;ACSL4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.4478528 | 0.8703832 | 0.0862866 | 0.5147799 | 1.0262587 | 6 | PLCB2;PLCB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_UREA_CYCLE | 0.4478528 | 0.8703832 | 0.0862866 | 0.5132006 | 1.0231103 | 6 | ASS1;ARG2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 0.4291755 | 0.8703832 | 0.0905429 | 0.3913415 | 1.0225916 | 18 | GSTA5;GSTA2;GSTA1;GSTP1;GSTA4;GSTA3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 0.4594017 | 0.8749836 | 0.0873098 | 0.4444402 | 1.0173738 | 11 | RYR1;CACNA1A;CALM3;CACNA1B;CACNA1E;CACNA1S;RYR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN | 0.4884211 | 0.8787182 | 0.0831291 | 0.5354838 | 1.0173735 | 5 | CFH;CFI;CD55 | non-significant |
| KEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING | 0.4539877 | 0.8723536 | 0.0855357 | 0.5092275 | 1.0151895 | 6 | MAPK1;RPS6KA3;RPS6KA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY | 0.4566116 | 0.8723536 | 0.0857844 | 0.4905725 | 1.0132884 | 7 | PLCB2;PLCB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 0.4675052 | 0.8771162 | 0.0852885 | 0.3606714 | 1.0056238 | 23 | PFKP;LDHC;LDHB;ENO1;PGAM1;GPI;GAPDH;PGK1;PFKL;PKM | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY | 0.4811715 | 0.8771162 | 0.0835991 | 0.4246167 | 1.0041157 | 12 | TNF;NFKB1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY | 0.4831933 | 0.8771162 | 0.0835991 | 0.4581603 | 1.0027338 | 9 | BIRC5;E2F1;CDC25A;CDC6;RAF1;SRC | non-significant |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.4432071 | 0.8703832 | 0.0916795 | 0.4024545 | 1.0018064 | 15 | VLDLR;PIK3CD;DAB1;RHEB;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY | 0.4808511 | 0.8771162 | 0.0845557 | 0.4466200 | 1.0001796 | 10 | NFKBIA;NFKB1;MAP3K7;IKBKG;RELA;TLR3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY | 0.4744376 | 0.8771162 | 0.0831291 | 0.5012341 | 0.9992540 | 6 | MAP3K5;DAXX | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 0.4762887 | 0.8771162 | 0.0833634 | 0.3335933 | 0.9992507 | 32 | GNB4;CHRM1;PIK3CG;GNGT2;GNG4;LPAR3;GNG7 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P15_CELL_CYCLE_G1_S | 0.4716157 | 0.8771162 | 0.0870516 | 0.4143435 | 0.9955755 | 13 | CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 0.4507659 | 0.8703832 | 0.0897105 | 0.3906339 | 0.9848655 | 16 | CDC20;PTTG1;CDC16 | non-significant |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 0.5157233 | 0.9021400 | 0.0799859 | 0.3528147 | 0.9837176 | 23 | GSTA5;GSTA2;GSTA1;GSTP1;GSTA4;GSTA3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 0.4703390 | 0.8771162 | 0.0855357 | 0.3829319 | 0.9822938 | 17 | CDC20;TRIP13;MAD2L1;BUB1B;CDC16;MAD2L1BP | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.5230126 | 0.9043150 | 0.0791317 | 0.3538798 | 0.9763057 | 22 | ITPR3;PLCB2;PLCB4;CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 0.4938525 | 0.8821723 | 0.0810802 | 0.3261569 | 0.9743262 | 31 | VEGFA;GNB4;MAPK1;GNGT2;GNG4;HIF1A;GNG7;NRAS;RAF1;FOS;GNG5;JUN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.5251046 | 0.9054032 | 0.0789210 | 0.3527566 | 0.9732070 | 22 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;APP;TUBB4A;TUBA1C;CDK5R1;CAPN2;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.5173824 | 0.9021400 | 0.0785029 | 0.4869870 | 0.9708511 | 6 | HK3;BAX | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.4897541 | 0.8787182 | 0.0815265 | 0.3248661 | 0.9655219 | 30 | ITGB7;ITGB6;ITGB4;ITGA9;ITGA4;ACTN4;ACTB;ACTN1;ITGB8;ITGA5;VCL;ITGA8;ACTG1;TLN1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 0.5294118 | 0.9064769 | 0.0787114 | 0.4394731 | 0.9618349 | 9 | ICOS;PIK3CD;ICOSLG | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.5167038 | 0.9021400 | 0.0831291 | 0.3859224 | 0.9606540 | 15 | TRADD;NFKBIA;NFKB1;MAP3K7;TRAF2;IKBKG;TNFRSF1A;RIPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.4945295 | 0.8821723 | 0.0845557 | 0.3808331 | 0.9601558 | 16 | PLCG2;NFATC3;EGFR;CALM3;PLCG1;NFATC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 0.5103734 | 0.9000603 | 0.0799859 | 0.3280193 | 0.9601400 | 28 | ITGB7;ITGB6;RAC2;ITGB4;ITGA9;RHOG;ITGA4;ELMO1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S | 0.5213675 | 0.9039958 | 0.0804200 | 0.4179983 | 0.9568453 | 11 | CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY | 0.5433884 | 0.9064769 | 0.0764767 | 0.4620274 | 0.9543277 | 7 | TNF;TRADD;TRAF2;TNFRSF1A;RIPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.5431579 | 0.9064769 | 0.0774768 | 0.4998828 | 0.9497347 | 5 | CASP3;BAX;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_EWSR1_WT1_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.5460123 | 0.9064769 | 0.0756946 | 0.4763676 | 0.9496805 | 6 | IL2RB;MLF1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_TP53_TO_TRANSCRIPTION | 0.5525210 | 0.9064769 | 0.0764767 | 0.4323631 | 0.9462739 | 9 | BAK1;GADD45A;BAX;CDKN1A;GADD45B | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 0.5273523 | 0.9064769 | 0.0810802 | 0.3742596 | 0.9435825 | 16 | ERBB2;MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY | 0.5548654 | 0.9064769 | 0.0755015 | 0.4471717 | 0.9398353 | 8 | MAP3K5;FOS;JUN;MAP2K4 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.5642702 | 0.9064769 | 0.0772747 | 0.3830007 | 0.9363618 | 14 | PIK3CD;NFKBIA;NFKB1;IKBKG;EGFR;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION | 0.5557895 | 0.9064769 | 0.0762797 | 0.4922556 | 0.9352436 | 5 | HEXA;GLB1;GALNS;HEXB | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 0.5471311 | 0.9064769 | 0.0756946 | 0.3135613 | 0.9319233 | 30 | ITGB7;ITGB6;RAC2;ITGB4;ITGA9;ITGA4;ELMO1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.5631470 | 0.9064769 | 0.0747385 | 0.4430858 | 0.9312479 | 8 | PIK3CD;EGFR;PIK3CA;AKT1;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S | 0.5756303 | 0.9136285 | 0.0743625 | 0.4251840 | 0.9305615 | 9 | CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 0.5640496 | 0.9064769 | 0.0745501 | 0.3433404 | 0.9293166 | 20 | CREB3L2;MAPK1;ATF4;NRAS;CREB5;RAF1;CREB3L1 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.5795207 | 0.9148432 | 0.0758887 | 0.3793164 | 0.9273546 | 14 | PLCG2;PRKCB;MAPK1;PRKCA;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.5564854 | 0.9064769 | 0.0758887 | 0.3905781 | 0.9236227 | 12 | CXCR4;PIK3CD;PIK3CA | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 0.5829876 | 0.9148432 | 0.0730744 | 0.3143811 | 0.9202200 | 28 | IL6;GNB4;PIK3CG;GNGT2;GNG4;NFKB1;GNG7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.5576923 | 0.9064769 | 0.0768737 | 0.3998891 | 0.9153915 | 11 | ITPR3;PLCB2;PLCB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 0.6008403 | 0.9196718 | 0.0721798 | 0.4160794 | 0.9106351 | 9 | PIK3CD;EGFR;PIK3CA;TGFA;AKT1;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 0.5968820 | 0.9196718 | 0.0755015 | 0.3655849 | 0.9100290 | 15 | CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY | 0.6008403 | 0.9196718 | 0.0721798 | 0.4157777 | 0.9099749 | 9 | VEGFA;HIF1A;TGFA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6106383 | 0.9196718 | 0.0720033 | 0.4059929 | 0.9091976 | 10 | ITPR3;PLCB2;PLCB4;SPTBN2 | non-significant |
| KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.6045549 | 0.9196718 | 0.0711327 | 0.4323847 | 0.9087570 | 8 | PIK3CD;EGFR;PIK3CA;TGFA;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 0.6100629 | 0.9196718 | 0.0713053 | 0.3253689 | 0.9071933 | 23 | TUBB3;TUBB;TUBA4A;TUBB6;TUBB2A;TUBB4A;TUBA1C;TUBB2B;TUBA1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.5969499 | 0.9196718 | 0.0743625 | 0.3702007 | 0.9050685 | 14 | PLCG2;PRKCB;MAPK1;PRKCA;RAF1;EGFR;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY | 0.6212766 | 0.9212545 | 0.0711327 | 0.4019583 | 0.9001625 | 10 | TNF;CASP3;TRADD;TRAF2;TNFRSF1A;RIPK1;CASP8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GRM1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6092437 | 0.9196718 | 0.0714786 | 0.4097867 | 0.8968629 | 9 | ITPR3;PLCB2;PLCB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_MESP2_SIGNALING | 0.5852632 | 0.9148432 | 0.0736213 | 0.4718960 | 0.8965621 | 5 | EPHA4;RBPJ;LFNG;RIPPLY2;TBX6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_NEF_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.6100218 | 0.9196718 | 0.0732559 | 0.3662915 | 0.8955113 | 14 | TRADD;NFKBIA;NFKB1;MAP3K7;TRAF2;IKBKG;RIPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.6226415 | 0.9212545 | 0.0702813 | 0.3208291 | 0.8945354 | 23 | CREB3L2;CAMK1D;ATF4;CAMK2D;CREB5;CREB3L1;CALM3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 0.6258352 | 0.9223619 | 0.0730744 | 0.3585899 | 0.8926168 | 15 | PLCG2;PRKCB;MAPK1;PRKCA;RAF1;EGFR;PLCG1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.6164948 | 0.9212545 | 0.0699459 | 0.3023260 | 0.8907295 | 29 | WNT6;WNT10A;WNT2;SMO;WNT5B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.6164948 | 0.9212545 | 0.0699459 | 0.3023260 | 0.8907295 | 29 | WNT6;WNT10A;WNT2;SMO;WNT5B | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 0.6155462 | 0.9212545 | 0.0709609 | 0.4068831 | 0.8905080 | 9 | CXCR4;ARHGEF1;ROCK2;GNA12 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.6407563 | 0.9245411 | 0.0689567 | 0.3056101 | 0.8854575 | 27 | RASD1;POMC;CREB3L2;ADCY7;ATF4;CREB5;ADCY3 | non-significant |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.6549587 | 0.9298611 | 0.0670513 | 0.2853287 | 0.8794234 | 37 | WNT6;WNT10A;TCF7L1;WNT2;FZD7;WNT5B;TCF7;FRAT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 0.6365546 | 0.9245411 | 0.0692836 | 0.3088647 | 0.8794067 | 26 | ITGB7;ITGB6;ITGB4;ITGA9;ITGA4;ITGB8;SRC;GIT2;ITGA5;ITGA8;ARHGEF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.6365503 | 0.9245411 | 0.0681513 | 0.3183484 | 0.8752881 | 21 | PRKCB;MAPK1;PLCB2;PLCB4;LHB;PRKCA;RAF1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6378947 | 0.9245411 | 0.0692836 | 0.3304426 | 0.8719548 | 19 | RYR1;ITPR3;CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S | 0.6359833 | 0.9245411 | 0.0691198 | 0.3680926 | 0.8704499 | 12 | CCND2;E2F3;E2F2;CDK6;E2F1;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_SECOND_CARBON_OXIDATION_2 | 0.6510638 | 0.9298611 | 0.0687943 | 0.3873814 | 0.8675182 | 10 | SDHA;SDHC;SDHD;FH;SUCLG1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6603774 | 0.9336350 | 0.0673624 | 0.3109660 | 0.8670350 | 23 | ITPR3;PLCB2;PLCB4;CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_NFKB_SIGNALING_PATHWAY | 0.6359918 | 0.9245411 | 0.0679923 | 0.4346440 | 0.8665009 | 6 | NFKBIA;NFKB1;IKBKG;RELA | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 0.6645702 | 0.9336350 | 0.0670513 | 0.3099723 | 0.8642644 | 23 | ITGB7;ITGB6;ITGB4;ITGA9;ITGA4;ITGB8;SRC;ITGA5 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.6666667 | 0.9336350 | 0.0668966 | 0.3095161 | 0.8629925 | 23 | ITGB7;ITGB6;ITGB4;ITGA9;ITGA4;ITGB8 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.6867220 | 0.9459115 | 0.0649408 | 0.2890657 | 0.8461196 | 28 | CREB3L2;CAMK1D;PLCB2;ATF4;PLCB4;CAMK2D;CREB5;CREB3L1;CALM3 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY | 0.6548117 | 0.9298611 | 0.0676760 | 0.3570775 | 0.8444019 | 12 | VEGFA;HIF1A;CUL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 0.6904232 | 0.9459115 | 0.0681513 | 0.3369806 | 0.8388260 | 15 | MYD88;TLR9;IRAK1;IRF7;TLR7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.7004219 | 0.9459115 | 0.0647943 | 0.2987277 | 0.8373410 | 24 | GNB4;PIK3CG;GNGT2;GNG4;GNG7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 0.7032520 | 0.9459115 | 0.0628004 | 0.2775591 | 0.8368357 | 33 | CREB3L2;GNB4;GNGT2;GNG4;ATF4;GNG7;CREB5;MAPK13 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 0.6659389 | 0.9336350 | 0.0689567 | 0.3458399 | 0.8309765 | 13 | LPAR3;LPAR2;ARHGEF1;LPAR5;ROCK2;GNA12;GNA13;ARHGEF11 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6799163 | 0.9457712 | 0.0658312 | 0.3489195 | 0.8251103 | 12 | MAPK1;NRAS;RAF1;FOS;JUN | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP | 0.6911765 | 0.9459115 | 0.0652353 | 0.3745021 | 0.8196387 | 9 | PNP;NT5C2;NT5E;LACC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKR_EIF2ALPHA_SIGNALING_PATHWAY | 0.7004132 | 0.9459115 | 0.0637845 | 0.3949829 | 0.8158459 | 7 | EIF2AK2;EIF2B3;EIF2S1;EIF2B5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 0.7193764 | 0.9459115 | 0.0661326 | 0.3273762 | 0.8149184 | 15 | MAPK1;PTK2B;NRAS;RAF1;SRC | non-significant |
| KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7148936 | 0.9459115 | 0.0642141 | 0.3609396 | 0.8083033 | 10 | PIK3CD;EGFR;PIK3CA;AKT1;MTOR;RPS6KB2;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY | 0.7066116 | 0.9459115 | 0.0633597 | 0.3908379 | 0.8072842 | 7 | STAT5A;JAK2;STAT5B | non-significant |
| KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7167756 | 0.9459115 | 0.0652353 | 0.3290197 | 0.8043890 | 14 | MAPK1;MET;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.6830266 | 0.9459115 | 0.0645031 | 0.4029669 | 0.8033498 | 6 | MAP2K3;MAP2K6;MAP2K4;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST | 0.7158120 | 0.9459115 | 0.0643583 | 0.3507847 | 0.8029858 | 11 | DDOST;RPN2;RPN1;STT3A;ALG6;STT3B | non-significant |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 0.7622951 | 0.9571210 | 0.0593488 | 0.2681617 | 0.8010776 | 31 | EZH2;JARID2;PHF19;CBX2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P53_MEDIATED_TRANSCRIPTION | 0.7212766 | 0.9459115 | 0.0637845 | 0.3570779 | 0.7996554 | 10 | BAK1;GADD45A;BAX;CDKN1A;GADD45B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.7100840 | 0.9459115 | 0.0639272 | 0.3649197 | 0.7986665 | 9 | MET;PIK3CD;PIK3CA | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA1_TO_P53_MEDIATED_TRANSCRIPTION | 0.7234043 | 0.9460907 | 0.0636424 | 0.3564481 | 0.7982449 | 10 | BAK1;GADD45A;BAX;CDKN1A;GADD45B | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR4_IRF3_7_SIGNALING_PATHWAY | 0.7184265 | 0.9459115 | 0.0626618 | 0.3775367 | 0.7934812 | 8 | TLR4;IRF7;TRAF3;IKBKE;IRF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.7801268 | 0.9657970 | 0.0597318 | 0.2810900 | 0.7925881 | 25 | GNB4;PIK3CG;GNGT2;GNG4;GNG7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION | 0.7280335 | 0.9463845 | 0.0625237 | 0.3321626 | 0.7854842 | 12 | CREB3L2;ATF4;PCNA;CREB5;CREB3L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS | 0.7055215 | 0.9459115 | 0.0629395 | 0.3926765 | 0.7828350 | 6 | UGP2;GYG1;GYG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 0.7055215 | 0.9459115 | 0.0629395 | 0.3920996 | 0.7816849 | 6 | PIK3CD;PIK3CA;AKT1;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP | 0.7184874 | 0.9459115 | 0.0633597 | 0.3571392 | 0.7816382 | 9 | PNP;NT5C2;NT5E;LACC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 0.7819706 | 0.9661474 | 0.0592219 | 0.2791848 | 0.7784228 | 23 | GNB4;GNGT2;GNG4;LPAR3;GNG7;LPAR2;GNG5;LPAR5 | non-significant |
| KEGG_MEDICUS_VARIANT_EREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7382979 | 0.9520966 | 0.0626618 | 0.3448568 | 0.7722869 | 10 | PIK3CD;EGFR;PIK3CA;AKT1;RPS6KB2;PIK3CB | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.8088235 | 0.9809867 | 0.0577309 | 0.2706901 | 0.7707150 | 26 | PROM1;LMO2;MEF2C;BMP2K | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.8054968 | 0.9795728 | 0.0582216 | 0.2935660 | 0.7671001 | 18 | PLCB2;PLCB4;PTGS2;NFATC3;CALM3;NFATC2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7734205 | 0.9617672 | 0.0615707 | 0.3134906 | 0.7664232 | 14 | MAPK1;PDGFRA;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.7564103 | 0.9571210 | 0.0617054 | 0.3329639 | 0.7621921 | 11 | PIK3CD;EGFR;PIK3CA;AKT1;MTOR;RPS6KB2;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 0.8224101 | 0.9811562 | 0.0572461 | 0.2909711 | 0.7603197 | 18 | TCP1;DKC1;GAR1;CCT4;CCT3;CCT7;CCT6A;TERT | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY | 0.7438017 | 0.9538429 | 0.0609039 | 0.3678189 | 0.7597381 | 7 | RAC2;SRC | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP | 0.7515528 | 0.9571210 | 0.0605093 | 0.3607285 | 0.7581549 | 8 | RASAL1;NRAS;RASA3;RASA2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.7198364 | 0.9459115 | 0.0619763 | 0.3798438 | 0.7572518 | 6 | MAPK1;MAPK13;MAPK14 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7556936 | 0.9571210 | 0.0602484 | 0.3584825 | 0.7534343 | 8 | PIK3CD;EGFR;PIK3CA;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 0.8361345 | 0.9835154 | 0.0561767 | 0.2640513 | 0.7518129 | 26 | GNB4;MAPK1;GNGT2;GNG4;GNG7;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY | 0.7606838 | 0.9571210 | 0.0614364 | 0.3272146 | 0.7490313 | 11 | RASSF5;NRAS;STK4;EGFR | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 0.7617021 | 0.9571210 | 0.0611693 | 0.3341959 | 0.7484123 | 10 | CD28;PIK3CD;CD80;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 0.8378947 | 0.9835154 | 0.0561767 | 0.2822267 | 0.7447251 | 19 | IFIH1;TANK;IRF7;TBKBP1;TRAF3;IKBKE;IRF3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS | 0.7648352 | 0.9583663 | 0.0625237 | 0.4191167 | 0.7397140 | 4 | HSD11B1;CBR1 | non-significant |
| KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7713675 | 0.9617672 | 0.0607719 | 0.3211072 | 0.7350507 | 11 | MAPK1;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION | 0.7970711 | 0.9712343 | 0.0582216 | 0.3103507 | 0.7339044 | 12 | SEC13;PREB;SEC24A;SEC23B;SEC23A;SAR1A;SEC24C;SEC31A;SEC31B;SAR1B;SEC24D;SEC24B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.7600000 | 0.9571210 | 0.0607719 | 0.3848478 | 0.7311779 | 5 | FOS;JUN;MAPK10 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050 | 0.7730061 | 0.9617672 | 0.0585938 | 0.3643423 | 0.7263483 | 6 | CASP3;BAX;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 0.8218263 | 0.9811562 | 0.0597318 | 0.2912595 | 0.7250152 | 15 | MAPK1;MET;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_ITPR1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.7913223 | 0.9699575 | 0.0579755 | 0.3460976 | 0.7148722 | 7 | PLCB2;PLCB4 | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.8098291 | 0.9809867 | 0.0584693 | 0.3102280 | 0.7101470 | 11 | PIK3CD;CBL;PIK3CA;AKT1;ABL1;PIK3CB;CRKL | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL | 0.8226496 | 0.9811562 | 0.0577309 | 0.3087730 | 0.7068163 | 11 | GRIN2D;P2RX5;P2RX7;P2RX3;P2RX1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 0.8127660 | 0.9811115 | 0.0580984 | 0.3152382 | 0.7059577 | 10 | SLC25A5;APP;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_PI3K_SIGNALING_PATHWAY | 0.8404255 | 0.9835154 | 0.0565300 | 0.3073604 | 0.6883159 | 10 | PIK3CD;ADRB2;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 0.8404255 | 0.9835154 | 0.0565300 | 0.3069173 | 0.6873236 | 10 | MET;PIK3CD;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY | 0.8404255 | 0.9835154 | 0.0565300 | 0.3068851 | 0.6872514 | 10 | MAPK1;RAF1;MAP2K1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.8214286 | 0.9811562 | 0.0570060 | 0.3139551 | 0.6871251 | 9 | ACTB;ITGA5;VCL;ACTG1;TLN1;ITGB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 0.8624454 | 0.9974792 | 0.0565300 | 0.2856427 | 0.6863359 | 13 | ITPR3;SLC25A5;SIGMAR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.8834746 | 0.9974792 | 0.0540088 | 0.2672568 | 0.6855649 | 17 | CREB3L2;ATF4;CREB5;STAR;CREB3L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27 | 0.8675214 | 0.9974792 | 0.0552496 | 0.2933130 | 0.6714267 | 11 | TEX10;DCAF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY | 0.8319328 | 0.9835154 | 0.0564118 | 0.3048808 | 0.6672650 | 9 | SLC16A10;RXRB;SLC16A2;THRA;ATP2A2;MYH6;RXRG;THRB;RXRA | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381 | 0.8912134 | 0.9974792 | 0.0530213 | 0.2772267 | 0.6555742 | 12 | MFNG;NOTCH1;NOTCH2;MAML2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 0.9133192 | 0.9974792 | 0.0523759 | 0.2491400 | 0.6510131 | 18 | FZD9;FZD7;RSPO3;LGR6 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 0.9109131 | 0.9974792 | 0.0549074 | 0.2612110 | 0.6502171 | 15 | GRIN2D;SLC25A5;APP | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY | 0.8824786 | 0.9974792 | 0.0544556 | 0.2840046 | 0.6501187 | 11 | BMP6;HAMP | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 0.9198218 | 0.9974792 | 0.0544556 | 0.2585789 | 0.6436652 | 15 | MAPK1;NRAS;FLT3LG;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST | 0.9039301 | 0.9974792 | 0.0543434 | 0.2640700 | 0.6345014 | 13 | BMP6;BMP7;GREM1;GDF5;BMP5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION | 0.8863636 | 0.9974792 | 0.0526973 | 0.3069449 | 0.6340014 | 7 | HDAC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 0.9061135 | 0.9974792 | 0.0542316 | 0.2636828 | 0.6335712 | 13 | LBR;DHCR7;SQLE;EBP;NSDHL | non-significant |
| KEGG_MEDICUS_VARIANT_DELETED_DMD_TO_DYSTROPHIN_ASSOCIATED_PROTEIN_COMPLEX | 0.8872340 | 0.9974792 | 0.0540088 | 0.2811831 | 0.6296934 | 10 | ACTB;SNTB1;ACTG1;DTNA | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.8813906 | 0.9974792 | 0.0524828 | 0.3148581 | 0.6276971 | 6 | ATF4;PRNP;EIF2AK3;EIF2S1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.8737060 | 0.9974792 | 0.0534572 | 0.2982980 | 0.6269426 | 8 | MAPK1;PROKR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55 | 0.8926316 | 0.9974792 | 0.0532386 | 0.3298416 | 0.6266709 | 5 | GORASP2;MAP1LC3B;LAMP2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9259259 | 0.9974792 | 0.0531298 | 0.2558086 | 0.6254022 | 14 | MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.9323467 | 0.9974792 | 0.0514265 | 0.2377301 | 0.6211986 | 18 | CREB3L2;ATF4;CREB5;STAR;CREB3L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.8907563 | 0.9974792 | 0.0532386 | 0.2833213 | 0.6200795 | 9 | MAPK1;PROKR1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9331849 | 0.9974792 | 0.0537873 | 0.2480419 | 0.6174362 | 15 | MAPK1;NRAS;RAF1;SRC | non-significant |
| KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 0.8928571 | 0.9974792 | 0.0531298 | 0.2819002 | 0.6169693 | 9 | PIK3CD;PAQR8;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.8881988 | 0.9974792 | 0.0526973 | 0.2924698 | 0.6146932 | 8 | MAPK1;PROKR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9376392 | 0.9974792 | 0.0535669 | 0.2461021 | 0.6126076 | 15 | MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_REFERENCE_V_D_J_RECOMBINATION | 0.9267782 | 0.9974792 | 0.0512184 | 0.2574280 | 0.6087550 | 12 | XRCC6;DCLRE1C;PRKDC;XRCC5;NHEJ1;XRCC4;LIG4;RAG2;POLL;RAG1;DNTT;POLM | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION | 0.9230769 | 0.9974792 | 0.0523759 | 0.2639911 | 0.6043055 | 11 | NOTCH1;NCSTN;ADAM17;NOTCH2;APH1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.9132231 | 0.9974792 | 0.0513223 | 0.2907070 | 0.6004616 | 7 | OPTN;FKBP8;FAF2;CISD2;CISD1;HK1;PINK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9420935 | 0.9974792 | 0.0533478 | 0.2409781 | 0.5998526 | 15 | MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.9109731 | 0.9974792 | 0.0515309 | 0.2837986 | 0.5964688 | 8 | PIK3CD;EGFR;PIK3CA;AKT1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 0.9513742 | 0.9974792 | 0.0504983 | 0.2268724 | 0.5928271 | 18 | GRIN2D;CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY | 0.9234043 | 0.9974792 | 0.0521630 | 0.2645541 | 0.5924535 | 10 | MAPK1;RAF1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 0.9117647 | 0.9974792 | 0.0521630 | 0.2688017 | 0.5883019 | 9 | PIK3CD;NRAS;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9556025 | 0.9974792 | 0.0502948 | 0.2228752 | 0.5823823 | 18 | PLCB2;PLCB4;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9586057 | 0.9974792 | 0.0515309 | 0.2365021 | 0.5782016 | 14 | MAPK1;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9586057 | 0.9974792 | 0.0515309 | 0.2344146 | 0.5730979 | 14 | MAPK1;NRAS;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUCONEOGENESIS | 0.9389474 | 0.9974792 | 0.0509083 | 0.2997948 | 0.5695845 | 5 | PC;MDH1;MDH2 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9643653 | 0.9974792 | 0.0522693 | 0.2281001 | 0.5677963 | 15 | MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_SPRED_AND_NF1 | 0.9325153 | 0.9974792 | 0.0498907 | 0.2813072 | 0.5608104 | 6 | NRAS;SPRED1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 0.9661734 | 0.9974792 | 0.0497903 | 0.2126063 | 0.5555492 | 18 | CAMK1D;CAMK2D;CALM3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9710468 | 0.9974792 | 0.0519512 | 0.2190764 | 0.5453341 | 15 | MAPK1;NRAS;RAF1;EGFR | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY | 0.9474790 | 0.9974792 | 0.0503964 | 0.2396524 | 0.5245055 | 9 | LPAR3;LPAR2;LPAR5 | non-significant |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.9759300 | 0.9974792 | 0.0509083 | 0.2078240 | 0.5239655 | 16 | CREB3L2;ATF4;CREB5;CREB3L1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 0.9722222 | 0.9974792 | 0.0499914 | 0.2264572 | 0.5183862 | 11 | PIK3CD;ADRB2;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 0.9777283 | 0.9974792 | 0.0516356 | 0.2079162 | 0.5175537 | 15 | PIK3CD;NRAS;FLT3LG;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 0.9607438 | 0.9974792 | 0.0489954 | 0.2493729 | 0.5150851 | 7 | PIK3CA;AKT1;MTOR;RPS6KB2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9716157 | 0.9974792 | 0.0510114 | 0.2142413 | 0.5147743 | 13 | ITPR3;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.9803493 | 0.9974792 | 0.0506004 | 0.2092811 | 0.5028560 | 13 | CASP3;SLC25A5;CYCS;VDAC3;APAF1;VDAC2;MCU;SLC25A31;VDAC1;SLC25A6;CASP9;SNCA;SLC25A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 0.9579832 | 0.9974792 | 0.0498907 | 0.2253743 | 0.4932562 | 9 | PIK3CD;EGFR;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 0.9873684 | 0.9974792 | 0.0486034 | 0.1863081 | 0.4916202 | 19 | GRIN2D;CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048 | 0.9814050 | 0.9974792 | 0.0480220 | 0.2247434 | 0.4642125 | 7 | CASP3;CYCS;HTRA2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9956236 | 0.9974792 | 0.0499914 | 0.1772777 | 0.4469523 | 16 | CASP3;SLC25A5 | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 0.9956236 | 0.9974792 | 0.0499914 | 0.1725536 | 0.4350419 | 16 | NFKBIA;NFKB1;IKBKG | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_DEGRADATION_BY_EXTRACELLULAR_ENDOLYSOSOMAL_DNASE | 0.9958678 | 0.9974792 | 0.0473534 | 0.1993891 | 0.4118426 | 7 | DNASE1L3;DNASE2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 1.0000000 | 1.0000000 | 0.0482150 | 0.1254383 | 0.3277755 | 18 | TANK;IRF7;TBKBP1;TRAF3;IKBKE;IRF3 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.9922929 | 0.9974792 | 0.0443293 | -0.2110059 | -0.4432157 | 8 | BAD;AKT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 0.9903661 | 0.9974792 | 0.0444181 | -0.2129586 | -0.4473172 | 8 | BAD;AKT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_BIFUNCTIONAL_GLYCOSYLASE | 0.9884393 | 0.9974792 | 0.0445071 | -0.2183379 | -0.4586164 | 8 | NTHL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CN_SIGNALING_PATHWAY | 0.9885496 | 0.9974792 | 0.0440640 | -0.2001183 | -0.4724387 | 12 | PPP3CB;NFATC4;PPP3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM | 0.9848197 | 0.9974792 | 0.0439759 | -0.2558196 | -0.4741717 | 5 | GRIN2C | non-significant |
| KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE | 0.9868421 | 0.9974792 | 0.0434507 | -0.2130864 | -0.4793488 | 10 | PPP3CB;PPP3CA;CALM2;CALM1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2 | 0.9866412 | 0.9974792 | 0.0441523 | -0.2067935 | -0.4881975 | 12 | PCGF3;PCGF5;RYBP;YAF2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS | 0.9831461 | 0.9974792 | 0.0434507 | -0.2142536 | -0.4927699 | 11 | GPX4;GCLM;GSS | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY | 0.9797422 | 0.9974792 | 0.0428451 | -0.1980266 | -0.5000735 | 14 | TBK1;IFNA6;IFNA8;IFNA2;IFNA16;IFNA21;IFNA5;IFNA10;TICAM1;IFNA4;TLR3;IKBKE;TRAF3;IRF7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 0.9797422 | 0.9974792 | 0.0428451 | -0.1995691 | -0.5039688 | 14 | CACNA1D | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM | 0.9688109 | 0.9974792 | 0.0459538 | -0.2742450 | -0.5312566 | 6 | GRIN2C;GRIN2B;GRIN2A;PDYN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.9688109 | 0.9974792 | 0.0459538 | -0.2750939 | -0.5329009 | 6 | SNCA;HSPA5;DDIT3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382 | 0.9632353 | 0.9974792 | 0.0435378 | -0.2236167 | -0.5467295 | 13 | HEY1;NOTCH4;NOTCH3;HES1 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_GLC_6P_TO_MAN_P_DOL | 0.9467681 | 0.9974792 | 0.0458620 | -0.2570507 | -0.5585011 | 9 | MPI;DPM2;DPM3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1 | 0.9473684 | 0.9974792 | 0.0453152 | -0.2487468 | -0.5595689 | 10 | BECN1;ATG14;PIK3C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 0.9503676 | 0.9974792 | 0.0441523 | -0.2316665 | -0.5664107 | 13 | PDGFRB;PDGFA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.9376218 | 0.9974792 | 0.0474483 | -0.2999604 | -0.5810713 | 6 | SOD1;HSPA5;DDIT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 0.9658444 | 0.9974792 | 0.0448645 | -0.2210090 | -0.5855875 | 19 | PPP2R5A;PPP2R2C;PPP2CA;PPP2R2A;PPP2CB | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION | 0.9376218 | 0.9974792 | 0.0474483 | -0.3025793 | -0.5861446 | 6 | ITPR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING | 0.9375000 | 0.9974792 | 0.0447749 | -0.2421055 | -0.5919335 | 13 | TP53BP1;PAXIP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 0.9427481 | 0.9974792 | 0.0462303 | -0.2157386 | -0.5939604 | 22 | CD86;PPP2R5A;PPP2R2C;PPP2CA;PPP2R2A;PPP2CB | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS | 0.9250936 | 0.9974792 | 0.0462303 | -0.2602212 | -0.5984927 | 11 | GLCE;EXTL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 0.9376147 | 0.9974792 | 0.0446854 | -0.2334386 | -0.6045535 | 16 | FZD8;FZD6;WNT5A;DVL1;FZD3;FZD4 | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9300184 | 0.9974792 | 0.0452247 | -0.2395979 | -0.6050528 | 14 | MAPK3;SOS2;HRAS;FLT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 0.9466667 | 0.9974792 | 0.0459538 | -0.2205300 | -0.6153233 | 23 | COPZ2;COPG2;TMED7;COPZ1;COPB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION | 0.9209559 | 0.9974792 | 0.0455878 | -0.2520337 | -0.6162073 | 13 | CREB3L4;HTT;CREB1;TAF4 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY | 0.8973384 | 0.9974792 | 0.0483118 | -0.2900742 | -0.6302522 | 9 | BMPR2;SMAD5;SMAD4;SMAD1;BMP10 | non-significant |
| KEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.8840304 | 0.9974792 | 0.0489954 | -0.2961838 | -0.6435266 | 9 | NBR1;TBK1;MAP1LC3A;SQSTM1;TAX1BP1;CALCOCO2;MAP1LC3C | non-significant |
| KEGG_MEDICUS_REFERENCE_HEME_BIOSYNTHESIS | 0.8783270 | 0.9974792 | 0.0492918 | -0.2988817 | -0.6493886 | 9 | ALAD;UROD;FECH | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 0.9005425 | 0.9974792 | 0.0458620 | -0.2538783 | -0.6517246 | 15 | BAD;SOS2;HRAS;AKT2;EGF;KRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 0.8862385 | 0.9974792 | 0.0472587 | -0.2534362 | -0.6563428 | 16 | PPP2R5A;PPP2R2C;PPP2CA;PPP2R2A;PPP2CB | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR | 0.8786765 | 0.9974792 | 0.0477342 | -0.2690654 | -0.6578489 | 13 | NBR1;WDFY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 0.8612717 | 0.9974792 | 0.0508054 | -0.3190682 | -0.6701993 | 8 | PLN;C4orf3;MLN;ATP2A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY | 0.8899431 | 0.9974792 | 0.0486034 | -0.3633748 | -0.6735296 | 5 | ARRB1;RB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_STRAD_STK11_TSC_SIGNALING_PATHWAY | 0.8477842 | 0.9882833 | 0.0515309 | -0.3252533 | -0.6831912 | 8 | PRKAA2;TSC2;STRADB;STK11 | non-significant |
| KEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION | 0.8571429 | 0.9954436 | 0.0498907 | -0.3067529 | -0.6900564 | 10 | AHCYL2;AHCYL1;GNMT;MAT2A | non-significant |
| KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY | 0.8362235 | 0.9835154 | 0.0521630 | -0.3337272 | -0.7009904 | 8 | ACVR2B;SMAD5;SMAD4;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY | 0.8389513 | 0.9835154 | 0.0507028 | -0.3050311 | -0.7015526 | 11 | SOS2;HRAS;RALGDS;EGF;KRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8408680 | 0.9835154 | 0.0489954 | -0.2737621 | -0.7027680 | 15 | PDGFRB;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_HYDROLYSIS_OF_SPHINGOMYELIN | 0.8262548 | 0.9835154 | 0.0528050 | -0.3485108 | -0.7084614 | 7 | ASAH1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION | 0.8421053 | 0.9835154 | 0.0523759 | -0.3660078 | -0.7090157 | 6 | SHARPIN;RBCK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ANXA2_S100A10_REGULATED_ACTIN_CYTOSKELETON | 0.8519924 | 0.9913220 | 0.0506004 | -0.3826750 | -0.7093033 | 5 | AHNAK | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4 | 0.8158379 | 0.9811562 | 0.0512184 | -0.2858094 | -0.7217502 | 14 | FZD8;LRP6;FZD6 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_MONOFUNCTIONAL_GLYCOSYLASE | 0.8188825 | 0.9811562 | 0.0531298 | -0.3442915 | -0.7231806 | 8 | MPG;SMUG1;POLB | non-significant |
| KEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX | 0.8131021 | 0.9811115 | 0.0534572 | -0.3470838 | -0.7290458 | 8 | NSMCE1 | non-significant |
| KEGG_MEDICUS_VARIANT_AREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.7894737 | 0.9696115 | 0.0536770 | -0.3313814 | -0.7454597 | 10 | AREG | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_NEIL_GLYCOSYLASE | 0.7870722 | 0.9685839 | 0.0543434 | -0.3445656 | -0.7486472 | 9 | NEIL1;NEIL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.7846442 | 0.9675194 | 0.0537873 | -0.3262520 | -0.7503594 | 11 | AREG | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7958412 | 0.9712343 | 0.0535669 | -0.2870468 | -0.7543265 | 18 | BCL2;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY | 0.7775735 | 0.9645652 | 0.0533478 | -0.3106692 | -0.7595677 | 13 | MAP3K1;SOS2;HRAS;EGF;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.7476980 | 0.9542784 | 0.0552496 | -0.3034062 | -0.7661869 | 14 | NBR1;MAP1LC3A;PINK1;SQSTM1;HK1;CISD1;TAX1BP1;CISD2;CALCOCO2;MAP1LC3C | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 0.7476980 | 0.9542784 | 0.0552496 | -0.3035939 | -0.7666610 | 14 | BAD;SOS2;HRAS;FLT3;AKT2;KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 0.7547170 | 0.9571210 | 0.0559429 | -0.3008498 | -0.7822348 | 17 | GHR;PRLR;LEP;EPOR | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_SIGNALING | 0.7442748 | 0.9538429 | 0.0571259 | -0.3328128 | -0.7857035 | 12 | RPA4;ATRIP;RAD17 | non-significant |
| KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION | 0.7292818 | 0.9463845 | 0.0564118 | -0.3111792 | -0.7858161 | 14 | FAN1;SLX4 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION | 0.7404580 | 0.9528971 | 0.0573667 | -0.3338923 | -0.7882522 | 12 | ATG4D;MAP1LC3A;ATG16L1;ATG12;ATG4B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.7244701 | 0.9460907 | 0.0588438 | -0.3761112 | -0.7900176 | 8 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.7270992 | 0.9463845 | 0.0582216 | -0.3365584 | -0.7945462 | 12 | TRH | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2 | 0.7362429 | 0.9520966 | 0.0573667 | -0.4307459 | -0.7984046 | 5 | BECN1;UVRAG;PIK3C3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY | 0.7186898 | 0.9459115 | 0.0592219 | -0.3801087 | -0.7984143 | 8 | NQO1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY | 0.7003676 | 0.9459115 | 0.0582216 | -0.3275479 | -0.8008351 | 13 | HEY1;JAG1;JAG2;NOTCH4;NOTCH3;HES1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7965779 | 0.9712343 | 0.0537873 | -0.2767925 | -0.8034731 | 27 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY | 0.7142857 | 0.9459115 | 0.0583453 | -0.3586836 | -0.8068774 | 10 | MAP3K12;MAP3K10;MAP2K7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7737643 | 0.9617672 | 0.0551352 | -0.2804446 | -0.8070718 | 26 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380 | 0.6870229 | 0.9459115 | 0.0609039 | -0.3490012 | -0.8239211 | 12 | HEY1;JAG1;NOTCH4;NOTCH3;HES1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.7373541 | 0.9520966 | 0.0584693 | -0.2800625 | -0.8259081 | 30 | KIF5C;TUBA3D | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6636528 | 0.9336350 | 0.0599892 | -0.3224818 | -0.8278351 | 15 | FGFR1;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 0.6901141 | 0.9459115 | 0.0605093 | -0.3841882 | -0.8347363 | 9 | FGFR1;FGFR2;AKT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.6698113 | 0.9359215 | 0.0615707 | -0.3220925 | -0.8374676 | 17 | PDGFRB;MAPK3;PDGFA;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_LOADING | 0.6863118 | 0.9459115 | 0.0607719 | -0.3868233 | -0.8404617 | 9 | MAU2;ATRX;RAD21;STAG2;NIPBL | non-significant |
| KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.6397059 | 0.9245411 | 0.0625237 | -0.3475977 | -0.8498556 | 13 | IL20;IL20RA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.6466165 | 0.9265177 | 0.0630790 | -0.3795171 | -0.8537433 | 10 | MAP1LC3A;PINK1;SQSTM1;HK1;CISD1;CISD2;MAP1LC3C | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S | 0.6531792 | 0.9298611 | 0.0637845 | -0.4076163 | -0.8561937 | 8 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 0.7126214 | 0.9459115 | 0.0599892 | -0.2627454 | -0.8587940 | 50 | GRPR;AGTR1;PTGER3;ITPR1;EDNRA;HTR2B;OXTR;F2R;ADRA1B;GNAQ;BDKRB2;ITPR2;EDNRB;PTGER1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6184448 | 0.9212545 | 0.0633597 | -0.3350343 | -0.8600581 | 15 | FGFR1;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.6447876 | 0.9260407 | 0.0645031 | -0.4271762 | -0.8683744 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.6742424 | 0.9399911 | 0.0614364 | -0.3079275 | -0.8687747 | 24 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG7_TO_ALG11 | 0.6374269 | 0.9245411 | 0.0655321 | -0.4487431 | -0.8692871 | 6 | ALG13;ALG1;ALG11;ALG14 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.6039783 | 0.9196718 | 0.0645031 | -0.3395160 | -0.8715630 | 15 | AREG;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_STRAND_BREAK_SIGNALING | 0.6235955 | 0.9212545 | 0.0646485 | -0.3794761 | -0.8727715 | 11 | RAD50;HERC2;UBE2N | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.6616257 | 0.9336350 | 0.0622490 | -0.3067039 | -0.8746066 | 25 | KIF5C;TUBA3D | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_FKTN_TO_LARGE | 0.6947566 | 0.9459115 | 0.0594760 | -0.5968176 | -0.8771064 | 2 | FKTN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.6439394 | 0.9260407 | 0.0636424 | -0.3138491 | -0.8854816 | 24 | KIF5C;TUBA3D | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPG_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.6274131 | 0.9224910 | 0.0658312 | -0.4358609 | -0.8860289 | 7 | SKP1;BTRC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.6219282 | 0.9212545 | 0.0652353 | -0.3164023 | -0.9022629 | 25 | CACNA1H;CAMK2B;CACNA1D;CREB3L4;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_POMT_TO_POMK | 0.5958254 | 0.9196718 | 0.0675189 | -0.4887617 | -0.9059391 | 5 | POMT2;POMGNT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.6098485 | 0.9196718 | 0.0662842 | -0.3227143 | -0.9104937 | 24 | KIF5C;TUBA3D | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 0.5958254 | 0.9196718 | 0.0675189 | -0.3440058 | -0.9114809 | 19 | BMPR1B;ACVR2B;BMP4;BMPR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 0.5846154 | 0.9148432 | 0.0691198 | -0.3168008 | -0.9192010 | 28 | RPA4;POLK;POLD4;XPA;RPA3;POLD2;GTF2H5;POLE4 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 0.6046512 | 0.9196718 | 0.0678338 | -0.2866632 | -0.9227344 | 46 | CCND1;WNT3;FZD8;WNT4;AXIN2;LRP6;LEF1;FZD6 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RAS_UBIQUITINATION_BY_CUL3_COMPLEX | 0.5847953 | 0.9148432 | 0.0697793 | -0.4769889 | -0.9240040 | 6 | CUL3;HRAS;RIT1;KRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.5803403 | 0.9148432 | 0.0686326 | -0.3246026 | -0.9256470 | 25 | CACNA1H;CAMK2B;CACNA1D;CREB3L4;CREB1 | non-significant |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.5969290 | 0.9196718 | 0.0679923 | -0.2883039 | -0.9264899 | 45 | CCND1;WNT3;FZD8;WNT4;AXIN2;LRP6;LEF1;FZD6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 0.5722543 | 0.9106052 | 0.0702813 | -0.3054795 | -0.9269918 | 34 | RPS23;RPS5;RPS13;RPS14;RPS15A;RPS9;RPS15;RPS4X;RPS2;RPS26;RPS3A;RPS24;RPS8;RPS29;RPS11;RPS3;RPS28 | non-significant |
| KEGG_MEDICUS_REFERENCE_INTRINSIC_APOPTOTIC_PATHWAY | 0.5422794 | 0.9064769 | 0.0706196 | -0.3807489 | -0.9309083 | 13 | BCL2;PMAIP1;BAD | non-significant |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 0.5357798 | 0.9064769 | 0.0711327 | -0.3603127 | -0.9331288 | 16 | HEY2;HEYL;HEY1;JAG1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5357798 | 0.9064769 | 0.0711327 | -0.3604640 | -0.9335206 | 16 | FGFR3;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.5432781 | 0.9064769 | 0.0706196 | -0.3701289 | -0.9346808 | 14 | IGF1R;IKBKB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.5684411 | 0.9068686 | 0.0699459 | -0.3248456 | -0.9348501 | 26 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 0.5667311 | 0.9064769 | 0.0709609 | -0.3187558 | -0.9365456 | 29 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY | 0.5665399 | 0.9064769 | 0.0701132 | -0.4317113 | -0.9379911 | 9 | MYL5;MYL7;MYL9;MYL10;RHOA | non-significant |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 0.5561905 | 0.9064769 | 0.0711327 | -0.3362051 | -0.9380804 | 23 | CACNA1H;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM | 0.5559772 | 0.9064769 | 0.0709609 | -0.5071388 | -0.9400018 | 5 | MAOA;MAOB | non-significant |
| KEGG_MEDICUS_REFERENCE_TRAPPI_RAB1_SIGNALING_PATHWAY | 0.5608365 | 0.9064769 | 0.0706196 | -0.4330049 | -0.9408017 | 9 | TRAPPC6A;TRAPPC5;TRAPPC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION | 0.5626204 | 0.9064769 | 0.0711327 | -0.4480557 | -0.9411363 | 8 | MIB1;JAG1;JAG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 0.5500000 | 0.9064769 | 0.0721798 | -0.3258385 | -0.9454238 | 28 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.5492424 | 0.9064769 | 0.0714786 | -0.3354871 | -0.9465303 | 24 | CACNA1H;CAMK2B;CACNA1D;CREB3L4;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME | 0.5501931 | 0.9064769 | 0.0723571 | -0.4660084 | -0.9473134 | 7 | PRKAR1A;PRKAR2A;PRKACB;PRKACG;PRKACA;PRKAR2B | non-significant |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 0.5192661 | 0.9028811 | 0.0727141 | -0.3673926 | -0.9514643 | 16 | RTEL1;TERF1;NHP2;RUVBL2;CTC1 | non-significant |
| KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5056180 | 0.8942215 | 0.0751182 | -0.4186314 | -0.9628263 | 11 | RET;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCND1_TO_CELL_CYCLE_G1_S | 0.5302144 | 0.9064769 | 0.0747385 | -0.5012264 | -0.9709558 | 6 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 0.5048544 | 0.8942215 | 0.0770737 | -0.3091447 | -0.9725316 | 41 | DYNLRB2;TUBA3D;DCTN4;DYNLT3;DYNC2H1;DYNC2LI1;OSBPL1A;DCTN6;DYNLRB1;DYNC1LI1;DYNC1I2;RAB7A;TUBA3C;ACTR10 | non-significant |
| KEGG_MEDICUS_REFERENCE_BILE_ACID_BIOSYNTHESIS | 0.4880295 | 0.8787182 | 0.0760837 | -0.3854729 | -0.9734288 | 14 | ACOX2;HSD17B4;SLC27A5;SCP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY | 0.4962547 | 0.8827059 | 0.0760837 | -0.4236278 | -0.9743178 | 11 | TBK1;IFNA6;IFNA8;IFNA2;IFNA16;IFNA21;IFNA5;IFNA10 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY | 0.5163776 | 0.9021400 | 0.0755015 | -0.4661712 | -0.9791876 | 8 | TGFB3;SMAD3;TGFB2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM | 0.4830827 | 0.8771162 | 0.0776799 | -0.4385545 | -0.9865510 | 10 | EPHX2;EPHX4;EPHX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 0.4785992 | 0.8771162 | 0.0799859 | -0.3314655 | -0.9871893 | 31 | FGFR3;FGFR1;FGF18;FGF10;FGFR2;FGF20;FGF3;AKT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION | 0.4812734 | 0.8771162 | 0.0776799 | -0.4292429 | -0.9872322 | 11 | RPA4;RAD51C | non-significant |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 0.4647619 | 0.8771162 | 0.0804200 | -0.3549324 | -0.9903331 | 23 | ESR1;CREB3L4;MAPK3;CREB1;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4729730 | 0.8771162 | 0.0802023 | -0.3717714 | -0.9929534 | 20 | PDE8B;PBX1;CREB3L4;CREB1;PDE11A | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4719536 | 0.8771162 | 0.0804200 | -0.3317142 | -0.9956422 | 32 | ADCY1;ADCY9;ADCY6;PBX1;CREB3L4;ADCY5;CREB1;MRAP | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.4495238 | 0.8703832 | 0.0822055 | -0.3571938 | -0.9966430 | 23 | ADCY1;ADCY9;ADCY6;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.4892788 | 0.8787182 | 0.0789210 | -0.5176953 | -1.0028587 | 6 | CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS | 0.4680451 | 0.8771162 | 0.0793435 | -0.4464072 | -1.0042160 | 10 | SHC2;SOS2;GAB2 | non-significant |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4513619 | 0.8703832 | 0.0831291 | -0.3401840 | -1.0131551 | 31 | ADCY1;ADCY9;ADCY6;PBX1;CREB3L4;ADCY5;CREB1;MRAP | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR | 0.4678363 | 0.8771162 | 0.0813027 | -0.5246651 | -1.0163603 | 6 | ACVR2B;BMPR2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4466546 | 0.8703832 | 0.0797706 | -0.3961285 | -1.0168915 | 15 | FGFR1;MAPK3;FGFR2;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.4404537 | 0.8703832 | 0.0828962 | -0.3872214 | -1.0175741 | 18 | MAPT;TUBA3D | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 0.4410058 | 0.8703832 | 0.0840746 | -0.3414774 | -1.0249466 | 32 | BRCA1;RPA4;RAD51C;POLK;POLD4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.4417293 | 0.8703832 | 0.0824344 | -0.4563239 | -1.0265243 | 10 | MYL5;ROCK1;MYL7;MYL9;MYL10;RHOA | non-significant |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 0.4319066 | 0.8703832 | 0.0855357 | -0.3484517 | -1.0275887 | 30 | DYNLRB2;DCTN4;DYNLT3;DYNC2H1;DYNC2LI1;DCTN6;DYNLRB1;DYNC1LI1;DYNC1I2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION | 0.4412331 | 0.8703832 | 0.0838361 | -0.4893299 | -1.0278323 | 8 | AGL;PYGL;G6PC3;PGM2 | non-significant |
| KEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION | 0.4393064 | 0.8703832 | 0.0840746 | -0.4906169 | -1.0305356 | 8 | IDUA;IDS;HYAL3;HYAL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 0.4356618 | 0.8703832 | 0.0819779 | -0.4226124 | -1.0332621 | 13 | IGF1R;TSC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 0.4168260 | 0.8703832 | 0.0865400 | -0.3375902 | -1.0332910 | 35 | ADCY1;SMARCD3;ADCY9;ADCY6 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.4234405 | 0.8703832 | 0.0850427 | -0.3943586 | -1.0363298 | 18 | MAPT;TUBA3D | non-significant |
| KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY | 0.4277457 | 0.8703832 | 0.0855357 | -0.4952368 | -1.0402397 | 8 | SMAD3;ACVR2B;NODAL;SMAD4;ACVR1C | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 0.3977055 | 0.8703832 | 0.0891647 | -0.3415478 | -1.0454044 | 35 | FGFR3;FGFR1;FGF18;MAPK3;FGF10;FGFR2;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY | 0.4142582 | 0.8703832 | 0.0873098 | -0.4984525 | -1.0469942 | 8 | SMAD3;ACVR2B;INHBA;SMAD4;ACVR1C | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.4171540 | 0.8703832 | 0.0875697 | -0.5434689 | -1.0527863 | 6 | BECN1;ATG14;PIK3C3 | non-significant |
| KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.4084778 | 0.8703832 | 0.0880945 | -0.5015726 | -1.0535480 | 8 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_HOLLIDAY_JUNCTION_RESOLUTION | 0.4326376 | 0.8703832 | 0.0840746 | -0.5686366 | -1.0539904 | 5 | SLX4 | non-significant |
| KEGG_MEDICUS_REFERENCE_C9ORF72_MEDIATED_AUTOPHAGY_INITIATION | 0.4092664 | 0.8703832 | 0.0880945 | -0.5227566 | -1.0626725 | 7 | SMCR8;RB1CC1;WDR41 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.4035088 | 0.8703832 | 0.0894367 | -0.5487937 | -1.0631013 | 6 | HTT;MAP3K10;MAP2K7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.3713733 | 0.8451473 | 0.0937465 | -0.3618488 | -1.0631583 | 29 | ADCY1;ADCY9;ADCY6;PBX1;CREB3L4;ADCY5;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION | 0.4034749 | 0.8703832 | 0.0888945 | -0.5240246 | -1.0652501 | 7 | C5;C6 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 0.3851718 | 0.8607269 | 0.0878313 | -0.4176567 | -1.0721561 | 15 | KITLG;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 0.3557692 | 0.8278991 | 0.0959207 | -0.3707070 | -1.0756103 | 28 | POLR2L;UVSSA;MNAT1;CDK7;CCNH;GTF2H5;POLR2J;POLR2G;POLR2E | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 0.3775322 | 0.8528922 | 0.0899861 | -0.4275598 | -1.0797102 | 14 | BRCA1;RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 0.3834297 | 0.8599383 | 0.0916795 | -0.5162058 | -1.0842849 | 8 | LRP2;CDON | non-significant |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 0.3384030 | 0.8101564 | 0.0982123 | -0.3776203 | -1.0867267 | 26 | CBX4;CBX8;BMI1;PHC3;MBD6;MBD5;SCML1;BAP1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY | 0.3740602 | 0.8481437 | 0.0916795 | -0.4845116 | -1.0899338 | 10 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION | 0.3479087 | 0.8219676 | 0.0965630 | -0.5064516 | -1.1003815 | 9 | CLU;C6;C8B;VTN;C7;CD59 | non-significant |
| KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY | 0.3609023 | 0.8284158 | 0.0937465 | -0.4898183 | -1.1018715 | 10 | ADCY9;ADCY6 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY | 0.3530534 | 0.8246795 | 0.0959207 | -0.4679693 | -1.1047806 | 12 | CCND1;AXIN2;LEF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY | 0.3629344 | 0.8289903 | 0.0949752 | -0.5442619 | -1.1063891 | 7 | CCND1;LEF1 | non-significant |
| KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.3571429 | 0.8279829 | 0.0959207 | -0.5483966 | -1.1147942 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 0.2447013 | 0.6967974 | 0.1198878 | -0.3636624 | -1.1474356 | 42 | DNALI1;TUBA3D;DNAH5;DCTN4;DNAH7;DNAL1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 0.2301741 | 0.6926151 | 0.1244342 | -0.3605994 | -1.1479442 | 44 | DNALI1;TUBA3D;DNAH5;DCTN4;DNAH7;DNAL1;HTT | non-significant |
| KEGG_MEDICUS_REFERENCE_TSC1_2_MTORC1_SIGNALING_PATHWAY | 0.3202247 | 0.7865837 | 0.1006334 | -0.4993772 | -1.1485366 | 11 | TELO2;MLST8;TSC2;DEPTOR;AKT1S1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 0.1967871 | 0.6411118 | 0.1388051 | -0.3241623 | -1.1522990 | 81 | RPS23;RPL22;RPL9;RPL29;RPL41;RPS5;RPS13;RPL13A;RPL14;RPS14;RPS15A;RPS9;RPLP1;RPL8;RPS15;RPL28;RPL12;RPS4X;RPLP0;RPL37A;RPS2;RPL31;RPL18;RPL36;RPS26;RPS3A;RPS24;RPS8;RPL15;RPL23A;RPL17;RPS29;RPS11;RPS3;RPS28;RPL10A;RPL30;RPL34;RPL11;RPL38;RPS21;RPL26;RPL37;RPLP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.3079848 | 0.7687201 | 0.1039585 | -0.5334381 | -1.1590157 | 9 | UQCRQ;CYC1;UQCRC2;UQCR11;UQCRB | non-significant |
| KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA | 0.3102119 | 0.7711695 | 0.1043440 | -0.5533320 | -1.1622681 | 8 | TGFB3;TGFB2;LTBP3;FBN1 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 0.2996255 | 0.7581397 | 0.1047328 | -0.5060738 | -1.1639385 | 11 | KITLG | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY | 0.2943470 | 0.7532323 | 0.1083943 | -0.6009186 | -1.1640755 | 6 | PLCD4;ITPR1;PLCD3;ITPR2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.2807339 | 0.7352587 | 0.1075544 | -0.4506006 | -1.1669543 | 16 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2770642 | 0.7329177 | 0.1083943 | -0.4513610 | -1.1689235 | 16 | ESR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 0.3014706 | 0.7581397 | 0.1031975 | -0.4816751 | -1.1776669 | 13 | GLI3;GLI1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2585895 | 0.7082607 | 0.1119183 | -0.4640063 | -1.1911390 | 15 | CCND1;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION | 0.2702703 | 0.7221520 | 0.1133129 | -0.5900798 | -1.1995289 | 7 | IDUA;HGSNAT;IDS;GNS;NAGLU;GUSB;SGSH | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_CAMP_SIGNALING_PATHWAY | 0.2559853 | 0.7061373 | 0.1137873 | -0.4753816 | -1.2004739 | 14 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2671756 | 0.7221520 | 0.1133129 | -0.5122773 | -1.2093829 | 12 | CCND1;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.2339623 | 0.6929313 | 0.1215433 | -0.4657818 | -1.2110720 | 17 | ADCY1;ADCY9;CX3CR1;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 0.2562620 | 0.7061373 | 0.1167392 | -0.5766243 | -1.2111933 | 8 | RET | non-significant |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 0.2423146 | 0.6967974 | 0.1162341 | -0.4718639 | -1.2113099 | 15 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2330275 | 0.6929313 | 0.1198878 | -0.4678614 | -1.2116558 | 16 | COX6C;COX7C;COX7A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 0.2174757 | 0.6764697 | 0.1287887 | -0.4497596 | -1.2136105 | 21 | CACNA2D2;CACNG1;CACNG4 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE | 0.2296015 | 0.6926151 | 0.1232572 | -0.6579821 | -1.2195958 | 5 | XYLT1;XYLT2;B3GAT3;B3GALT6 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 0.2264151 | 0.6926151 | 0.1238422 | -0.4695145 | -1.2207774 | 17 | MNAT1;CDK7;CCNH;CETN2;GTF2H5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 0.2509506 | 0.7032059 | 0.1172497 | -0.5635268 | -1.2243903 | 9 | CREBBP;TBK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION | 0.2413127 | 0.6967974 | 0.1209851 | -0.6030997 | -1.2259961 | 7 | IVD;HMGCL;MCCC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION | 0.2397004 | 0.6967974 | 0.1193484 | -0.5333671 | -1.2267113 | 11 | ACADSB;ACADS;ACAT1;ECHS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.2165138 | 0.6764697 | 0.1250334 | -0.4756881 | -1.2319253 | 16 | CCND1;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR | 0.2375691 | 0.6967974 | 0.1188150 | -0.4895980 | -1.2363743 | 14 | VPS18;VPS41;VPS39;RAB7A;MAP1LC3A;EPG5 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BPA_TO_RAS_ERK_SIGNALING_PATHWAY | 0.2316176 | 0.6926151 | 0.1204334 | -0.5097794 | -1.2463803 | 13 | ESR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY | 0.2161654 | 0.6764697 | 0.1268757 | -0.5577783 | -1.2547511 | 10 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY | 0.2148289 | 0.6764697 | 0.1281429 | -0.5776531 | -1.2550828 | 9 | BMPR1B;AMH;AMHR2;SMAD5;SMAD4;ACVR1;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 0.1898734 | 0.6251683 | 0.1335550 | -0.4961966 | -1.2737738 | 15 | ADCY1;ADCY9;ADCY6;ADCY5;PLN | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_RXRA_LXRA_MEDIATED_TRANSCRIPTION | 0.1910331 | 0.6256588 | 0.1388051 | -0.6586535 | -1.2759173 | 6 | CCND1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.1844485 | 0.6105540 | 0.1357409 | -0.4980287 | -1.2784770 | 15 | CCND1;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 0.1033797 | 0.4603744 | 0.1957890 | -0.3864811 | -1.2787802 | 54 | ERBB4;RET;MST1;FGFR3;ERBB3;PDGFD;FGFR1;ITPR1;NTRK2;PDGFRB;FGF18;PDGFA;FGF10;FGFR2;PDGFC | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY | 0.1814672 | 0.6067892 | 0.1420566 | -0.6328934 | -1.2865613 | 7 | BMPR1B;BMPR2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1773585 | 0.6065464 | 0.1420566 | -0.4950217 | -1.2870982 | 17 | COX6C;COX7C;COX7A1;COX4I2;COX6A1;AS3MT;COX8A;COX7B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.1823308 | 0.6067892 | 0.1395997 | -0.5739595 | -1.2911514 | 10 | UQCRQ;HTT;CYC1;UQCRC2;UQCR11;UQCRB | non-significant |
| KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 0.1797753 | 0.6067892 | 0.1404062 | -0.5625468 | -1.2938229 | 11 | ERBB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION | 0.1612903 | 0.5599550 | 0.1501698 | -0.6995828 | -1.2967044 | 5 | HGD;FAH | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 0.1688073 | 0.5805097 | 0.1437590 | -0.5025593 | -1.3015156 | 16 | IGF1R;IGF2;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.1559454 | 0.5573229 | 0.1552420 | -0.6731884 | -1.3040737 | 6 | HTT;BECN1;ATG14;PIK3C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION | 0.1522158 | 0.5567088 | 0.1563124 | -0.6280826 | -1.3192810 | 8 | RABEP1;EEA1;PIK3C3;RAB5B;RABGEF1;RAB5C | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 0.1522158 | 0.5567088 | 0.1563124 | -0.6286871 | -1.3205507 | 8 | PGR | non-significant |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.1518987 | 0.5567088 | 0.1511488 | -0.5153984 | -1.3230665 | 15 | IGF1R;IGF2;MAPK3;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 0.1300971 | 0.5162186 | 0.1709323 | -0.4909497 | -1.3247561 | 21 | CACNA2D2;CACNG1;CACNG4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0867052 | 0.4219496 | 0.2114002 | -0.4278326 | -1.3322791 | 39 | NDUFC2;NDUFA7;NDUFA2;NDUFB10;NDUFS8;NDUFS4;NDUFA5;NDUFC1;NDUFA4;NDUFB4;NDUFB1;NDUFAB1;NDUFS7 | non-significant |
| KEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.1463878 | 0.5525248 | 0.1585141 | -0.6137865 | -1.3335910 | 9 | VPS18;VPS41;VPS39;RAB7A | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1392405 | 0.5386867 | 0.1585141 | -0.5214292 | -1.3385480 | 15 | COX6C;COX7C;COX7A1;COX4I2;COX6A1;COX8A;COX7B | non-significant |
| KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 0.1195446 | 0.4966316 | 0.1766943 | -0.7236248 | -1.3412671 | 5 | CYP21A2;HSD11B2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.1310212 | 0.5163524 | 0.1695706 | -0.6401903 | -1.3447130 | 8 | VPS18;VPS41;VPS39;RAB7A | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 0.1240458 | 0.5051602 | 0.1737478 | -0.5697200 | -1.3449934 | 12 | ESR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0806142 | 0.4090180 | 0.2192503 | -0.4339800 | -1.3474524 | 38 | NDUFC2;NDUFA7;NDUFA2;NDUFB10;NDUFS8;NDUFS4;NDUFA5;NDUFC1;NDUFA4;NDUFB4;NDUFB1;NDUFAB1;NDUFS7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0828516 | 0.4135900 | 0.2165428 | -0.4330480 | -1.3485199 | 39 | NDUFC2;NDUFA7;NDUFA2;NDUFB10;NDUFS8;NDUFS4;NDUFA5;NDUFC1;NDUFA4;NDUFB4;NDUFB1;NDUFAB1;NDUFS7;NDUFB7;PINK1;NDUFA10;NDUFV2;NDUFA13;NDUFV3;NDUFA3;NDUFB6 | non-significant |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 0.0606654 | 0.3542628 | 0.2572065 | -0.4057919 | -1.3510611 | 56 | NDUFC2;NDUFAF1;COX20;COA3;NDUFAF3;UQCRQ;NDUFA2;NDUFB10;CYC1;NDUFS8;COX14;UQCRC2;NDUFS4;NDUFA4;COX16;UQCRB;NDUFAF6;COX11;NDUFS7;NDUFAF2;COX8A;COA5;NDUFB7;UCP1;NDUFA10 | non-significant |
| KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 0.1111111 | 0.4877857 | 0.1864326 | -0.6976492 | -1.3514582 | 6 | MAGI2;MAGI1;PTEN;AKT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 0.0571992 | 0.3542628 | 0.2663507 | -0.3735001 | -1.3532113 | 88 | ERBB4;IGF1R;KITLG;IGF2;FGFR3;ERBB3;AREG;PDGFD;FGFR1;PIK3R1;INSR;NTRK2;PDGFRB;FGF18;PIK3R2;PDGFA;FGF10;FGFR2;NTF4;PDGFC;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1183206 | 0.4951717 | 0.1782199 | -0.5768603 | -1.3618503 | 12 | KIF5C | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 0.0455869 | 0.3281199 | 0.3217759 | -0.3841852 | -1.3670426 | 82 | ERBB4;IGF1R;KITLG;IGF2;FGFR3;ERBB3;AREG;PDGFD;FGFR1;PIK3R1;INSR;NTRK2;PDGFRB;FGF18;PIK3R2;PDGFA;FGF10;FGFR2;NTF4;PDGFC | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 0.0248330 | 0.2255332 | 0.3524879 | -0.3779576 | -1.3715445 | 91 | ERBB4;IGF1R;RET;KITLG;IGF2;FGFR3;ERBB3;AREG;PDGFD;FGFR1;INSR;NTRK2;ARTN;PDGFRB;FGF18;MAPK3;PDGFA;FGF10;FGFR2;NTF4;PDGFC;SOS2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_PAI | 0.0974659 | 0.4477396 | 0.1999152 | -0.7107976 | -1.3769287 | 6 | SERPINA5;PLAT | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 0.1229656 | 0.5051602 | 0.1695706 | -0.5369342 | -1.3783504 | 15 | TELO2;MLST8;BECN1;DEPTOR;AKT1S1;ATG14;PIK3C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION | 0.1165414 | 0.4951717 | 0.1782199 | -0.6129337 | -1.3788260 | 10 | ACADSB;ACADS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0638298 | 0.3685739 | 0.2489111 | -0.4334876 | -1.3799788 | 44 | MAPT;NDUFC2;NDUFA7;NDUFA2;NDUFB10;NDUFS8;NDUFS4;NDUFA5;NDUFC1;NDUFA4;NDUFB4;NDUFB1;NDUFAB1;NDUFS7;CDK5;CAPN1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.0674374 | 0.3760697 | 0.2413400 | -0.4453732 | -1.3869009 | 39 | NDUFC2;NDUFA7;NDUFA2;NDUFB10;NDUFS8;NDUFS4;NDUFA5;NDUFC1;NDUFA4;NDUFB4;SNCA;NDUFB1;NDUFAB1;NDUFS7 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN | 0.0877193 | 0.4219496 | 0.2114002 | -0.7211792 | -1.3970395 | 6 | BECN1;UVRAG;ATG14;PIK3C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 0.0812854 | 0.4090707 | 0.2165428 | -0.4914906 | -1.4015500 | 25 | ERBB4;IGF1R;FGFR3;ERBB3;FGFR1;INSR;NTRK2;PDGFRB;FGFR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY | 0.0994475 | 0.4526324 | 0.1918922 | -0.5564828 | -1.4052775 | 14 | NPRL2;TELO2;MLST8;RRAGB;DEPTOR;AKT1S1;NPRL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_VALINE_DEGRADATION | 0.0770713 | 0.3992852 | 0.2249661 | -0.6756992 | -1.4192991 | 8 | ALDH6A1;ACADS;ECHS1;HIBADH;HIBCH | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 0.0976492 | 0.4477396 | 0.1918922 | -0.5579452 | -1.4322871 | 15 | RBBP8;BRCA1;RAD50;RPA4 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.0698529 | 0.3860622 | 0.2311267 | -0.5938908 | -1.4520275 | 13 | HPGD;FUT8;SIX1;SIX4;EYA1;HOXA10;HOXA11 | non-significant |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 0.0752294 | 0.3992852 | 0.2220560 | -0.5652217 | -1.4637973 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CREATINE_PATHWAY | 0.0495292 | 0.3433963 | 0.3217759 | -0.7655688 | -1.4830293 | 6 | GAMT;GATM;CKMT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0517350 | 0.3480868 | 0.3217759 | -0.6873897 | -1.4935107 | 9 | KIF5C | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0600860 | 0.3542628 | 0.3217759 | -0.7350948 | -1.4943189 | 7 | ESR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 0.0413875 | 0.3136029 | 0.3217759 | -0.6564693 | -1.5098389 | 11 | IGF1R;IGF2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0431603 | 0.3143082 | 0.3217759 | -0.5267528 | -1.5290578 | 27 | DNALI1;DNAH5;DCTN4;DNAH7;DNAL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 0.0659803 | 0.3728214 | 0.2878051 | -0.5906345 | -1.5296106 | 16 | CCND1;PGR | non-significant |
| KEGG_MEDICUS_REFERENCE_RENIN_ANGIOTENSIN_SIGNALING_PATHWAY | 0.0160396 | 0.1701803 | 0.3524879 | -0.8316585 | -1.5415119 | 5 | AGTR1;AGT | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS | 0.0083690 | 0.1167438 | 0.3807304 | -0.8920724 | -1.5583412 | 4 | SULT1A2;SULT1A1;SULT1A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 0.0504831 | 0.3433963 | 0.3217759 | -0.6075885 | -1.5735177 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0116749 | 0.1445348 | 0.3807304 | -0.5794074 | -1.6819035 | 27 | DNALI1;DNAH5;DCTN4;DNAH7;DNAL1;DCTN6;SOD1;DNAI1;DNAH9;ACTR10 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 0.0018706 | 0.0378688 | 0.4550599 | -0.9078236 | -1.6826870 | 5 | SCUBE2;HHAT;DISP1 | significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 0.0092166 | 0.1240234 | 0.3807304 | -0.5903510 | -1.6834634 | 25 | CACNA2D2;CACNA1H;CACNG1;CACNA1D;CACNG4 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 0.0012241 | 0.0270623 | 0.4550599 | -0.6521348 | -1.8399079 | 24 | PIGT;PIGH;PIGB;PIGX;PIGF;PIGQ;PIGV;GPAA1;PIGG;PIGN;PIGP;PGAP1;MPPE1;PIGK;DPM2 | significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0000009 | 0.0001321 | 0.6594444 | -0.9103855 | -2.0938303 | 11 | TFF1;ESR1;PGR;BCL2;KRT19 | significant |
| | | 0% | |== | 3% | |==== | 6% | |====== | 9% | |======== | 12% | |========== | 15% | |============ | 18% | |============== | 21% | |================ | 24% | |=================== | 26% | |===================== | 29% | |======================= | 32% | |========================= | 35% | |=========================== | 38% | |============================= | 41% | |=============================== | 44% | |================================= | 47% | |=================================== | 50% | |===================================== | 53% | |======================================= | 56% | |========================================= | 59% | |=========================================== | 62% | |============================================= | 65% | |=============================================== | 68% | |================================================= | 71% | |=================================================== | 74% | |====================================================== | 76% | |======================================================== | 79% | |========================================================== | 82% | |============================================================ | 85% | |============================================================== | 88% | |================================================================ | 91% | |================================================================== | 94% | |==================================================================== | 97% | |======================================================================| 100%
| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0000004 | 0.0002295 | 0.6749629 | 0.8043145 | 2.2963612 | 23 | IL21R;STAT1;IL2RB;IL7R;IL15;IL2RG;IL2RA;STAT5A;IL15RA;STAT3;IL21;JAK3;IL7 | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES | 0.0000015 | 0.0004028 | 0.6435518 | 0.8918513 | 2.2397086 | 13 | HLA-DOB;HLA-DQA1;CD74;HLA-DPB1;HLA-DPA1;HLA-DMA;HLA-DRB5;HLA-DRB1;HLA-DQA2;HLA-DQB1;HLA-DRA | significant |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 0.0000020 | 0.0004028 | 0.6272567 | 0.7357555 | 2.2112525 | 30 | MCM10;MCM2;MCM4;GINS4;RFC2;MCM5;MCM3;CDC45;RFC4;MCM6;RPA2;RFC5;MCM7;PCNA;PRIM2;GINS3;POLE3;POLA2;WDHD1;RPA1;GINS1;RFC3 | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 0.0000091 | 0.0009411 | 0.5933255 | 0.7598085 | 2.1900912 | 24 | CCNE1;MCM2;CCNA2;MCM4;MCM5;MCM3;CDT1;ORC6;CDC45;CDC7;MCM6;TICRR;MCM7;ORC1;CCNA1;MTBP;ORC3;DBF4 | significant |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 0.0000358 | 0.0022159 | 0.5573322 | 0.8192209 | 2.1441703 | 15 | MCM2;MCM4;GINS4;MCM5;MCM3;CDC45;MCM6;VCP;MCM7;GINS3;TRAIP | significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 0.0000312 | 0.0022159 | 0.5573322 | 0.7827012 | 2.1424093 | 18 | MCM2;MCM4;GINS4;MCM5;MCM3;CDC45;PIF1;MCM6;VCP;MCM7;GINS3 | significant |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 0.0000201 | 0.0017786 | 0.5756103 | 0.7145344 | 2.1280468 | 27 | MCM2;MCM4;GINS4;MCM5;MCM3;CDT1;ORC6;CDC45;MCM6;TICRR;MCM7;ORC1;GINS3;POLE3;MTBP;ORC3;GINS1;TOPBP1 | significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0000345 | 0.0022159 | 0.5573322 | 0.8545582 | 2.1119358 | 12 | TAP1;HLA-F;HLA-E;HLA-C;HLA-A;B2M;HLA-G;TAPBP;TAP2;HLA-B | significant |
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 0.0000062 | 0.0007652 | 0.6105269 | 0.6511423 | 2.1096561 | 44 | IL12RB2;STAT1;IFNG;IL2RB;IL7R;IL15;PIM1;IL2RG;IL2RA;STAT5A;IFNAR2;IL15RA;JAK2;IL23A;STAT3;IL13;IL3RA;STAT4;IL6;JAK3;IFNGR1;IL7;IL12A | significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION | 0.0000900 | 0.0050656 | 0.5384341 | 0.8363963 | 2.1004442 | 13 | HLA-DOB;HLA-DQA1;HLA-DPB1;HLA-DPA1;HLA-DMA;HLA-DRB5;HLA-DRB1;HLA-DQA2;HLA-DQB1;HLA-DRA | significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 0.0008967 | 0.0326521 | 0.4772708 | 0.7903832 | 1.9848915 | 13 | CCL5;CX3CL1;CCL2;CCL4;CCL3 | significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 0.0002514 | 0.0121274 | 0.4984931 | 0.6551020 | 1.9624694 | 29 | NUP205;SEH1L;NXT2;NUP210;NUP93;NUP155;NUP88;NDC1;NXT1;NUP62;NUP214;NUP160;DDX19B;NXF1;NUP37 | significant |
| KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M | 0.0003514 | 0.0155352 | 0.4984931 | 0.8427229 | 1.9496122 | 10 | CHEK1;CHEK2;CDC25B;CDK1;CCNB2;ATM;ATR | significant |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0014992 | 0.0515574 | 0.4550599 | 0.6909091 | 1.9188325 | 19 | LCK;CD3D;PLCG2;ZAP70;CD247;CD3G;VAV1;LCP2;LAT | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0002547 | 0.0121274 | 0.4984931 | 0.9087229 | 1.9000031 | 7 | HLA-F;HLA-E;HLA-C;HLA-A;B2M;HLA-G;HLA-B | significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 0.0023619 | 0.0639724 | 0.4317077 | 0.7176124 | 1.8982011 | 16 | NDC80;CDCA8;CENPW;NUF2;AURKB;INCENP;BIRC5;PMF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION | 0.0005589 | 0.0230624 | 0.4772708 | 0.8639958 | 1.8835111 | 8 | MCM2;MCM4;MCM5;MCM3;PIF1;MCM6;MCM7 | significant |
| KEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY | 0.0038955 | 0.0861195 | 0.4317077 | 0.7153796 | 1.8427296 | 14 | FANCE;FANCA;FANCG;UBE2T;FANCC;ATR;FANCL;TOPBP1;FANCB | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 0.0037070 | 0.0849863 | 0.4317077 | 0.6631685 | 1.8417896 | 19 | TUBB2B;CENPF;TUBB;TUBB3;CENPE;TUBB6;BUB1B;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M | 0.0021308 | 0.0639724 | 0.4317077 | 0.8135528 | 1.8415247 | 9 | CHEK1;CDK1;CCNB2;ATM;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_RECRUITMENT_AND_FORMATION_OF_THE_MCC | 0.0023744 | 0.0639724 | 0.4317077 | 0.8105788 | 1.8347930 | 9 | CDC20;NDC80;TTK;BUB1;BUB1B;AURKB;MAD2L1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00264 | 0.0023301 | 0.0639724 | 0.4317077 | 0.7653155 | 1.8276163 | 11 | CCNE1;CCNA2;E2F3;SKP2;E2F2;E2F1;CCNA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00536 | 0.0025011 | 0.0645068 | 0.4317077 | 0.7634484 | 1.8231575 | 11 | CDKN2A;CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0006394 | 0.0247374 | 0.4772708 | 0.9086711 | 1.8066244 | 6 | HLA-F;HLA-E;HLA-C;HLA-A;HLA-G;HLA-B | significant |
| KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX | 0.0043394 | 0.0866487 | 0.4070179 | 0.7485380 | 1.7875507 | 11 | NDC80;NUF2;CENPE;AURKB;AURKA;SPAG5;PPP1CA;PPP1CC;PPP1CB;SPC25 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00482 | 0.0059142 | 0.1039612 | 0.4070179 | 0.7856265 | 1.7783120 | 9 | CCNE1;CCNA2;E2F3;E2F2;E2F1;CCNA1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00497 | 0.0060774 | 0.1039612 | 0.4070179 | 0.7832480 | 1.7729279 | 9 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0105724 | 0.1308861 | 0.3807304 | 0.6698995 | 1.7719928 | 16 | STAT1;IFNG;IL27;JAK2;STAT3;IFNGR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_CANONICAL_INFLAMMASOME_SIGNALING_PATHWAY | 0.0054730 | 0.1035137 | 0.4070179 | 0.8422463 | 1.7610105 | 7 | CASP1;IL1B;CASP4;IL18;CASP5;NLRP3;PYCARD | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0061314 | 0.1039612 | 0.4070179 | 0.8401201 | 1.7565650 | 7 | HLA-F;HLA-E;HLA-C;HLA-A;HLA-G;HLA-B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M | 0.0096460 | 0.1259970 | 0.3807304 | 0.7587663 | 1.7553813 | 10 | CHEK1;CDK1;CCNB2;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 0.0086358 | 0.1259970 | 0.3807304 | 0.6234345 | 1.7446618 | 20 | TLR1;MYD88;TNF;TLR2;IRAK1;IL6;NFKB1;IL12A;MAP3K7;IKBKG;RELA | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 0.0067535 | 0.1071898 | 0.4070179 | 0.6472401 | 1.7438497 | 17 | NCK1;NCK2;ARPC1B;WIPF1;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A | non-significant |
| KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0110118 | 0.1336531 | 0.3807304 | 0.7534885 | 1.7431714 | 10 | IL12RB2;JAK2;IL23A;STAT3;STAT4;IL12A;TYK2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 0.0043344 | 0.0866487 | 0.4070179 | 0.6163489 | 1.7412629 | 22 | TUBB2B;KIF2C;TUBB;TUBB3;TUBB6;AURKB;TUBB2A;TUBA1C;TUBA1A;AURKA;TUBA4A;KIF18B;TUBB4A | non-significant |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 0.0041069 | 0.0866487 | 0.4070179 | 0.5953129 | 1.7379867 | 26 | STAT1;IFNG;STAT5A;IFNAR2;JAK2;STAT3;STAT4;JAK3;IFNGR1;TYK2;IFNGR2;STAT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE | 0.0023770 | 0.0639724 | 0.4317077 | 0.9055980 | 1.7350903 | 5 | C1QA;C1QB;C1QC;C1S;C1R | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 0.0118222 | 0.1407301 | 0.3807304 | 0.6234075 | 1.7313632 | 19 | TUBB2B;TUBB;TUBB3;TUBB6;PLK1;PSRC1;TUBB2A;TUBA1C;TUBA1A;TUBA4A;KIF2A;TUBB4A | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00498 | 0.0055185 | 0.1035137 | 0.4070179 | 0.7928499 | 1.7284130 | 8 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE | 0.0218319 | 0.2006472 | 0.3524879 | 0.6966318 | 1.7216400 | 12 | NDC80;TTK;NUF2;SKA3;AURKB;SKA1;PPP1CA;PPP1CC;PPP1CB | non-significant |
| KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M | 0.0096768 | 0.1259970 | 0.3807304 | 0.8177669 | 1.7098278 | 7 | CHEK1;CDK1;CCNB2;ATR | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 0.0074858 | 0.1158432 | 0.4070179 | 0.5999571 | 1.6949539 | 22 | TUBB2B;TUBB;TUBB3;TUBB6;TACC3;TUBB2A;TUBA1C;CLTA;TUBA1A;AURKA;TUBA4A;CKAP5;TUBB4A | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_P27_CELL_CYCLE_G1_S | 0.0139774 | 0.1602229 | 0.3807304 | 0.8035217 | 1.6800432 | 7 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 0.0204920 | 0.1955259 | 0.3524879 | 0.6399970 | 1.6750825 | 15 | CCNE1;CKS1B;E2F3;SKP2;E2F2;CUL1;E2F1;MYC | non-significant |
| KEGG_MEDICUS_REFERENCE_P27_CELL_CYCLE_G1_S | 0.0175715 | 0.1812792 | 0.3524879 | 0.6494707 | 1.6729564 | 14 | CCNE1;CCNA2;E2F3;SKP2;E2F2;CUL1;E2F1;CCNA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY | 0.0099413 | 0.1259970 | 0.3807304 | 0.8400319 | 1.6701556 | 6 | CASP1;IL1B;IL18;NLRP3;PYCARD;IL33 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0167894 | 0.1761469 | 0.3524879 | 0.7967195 | 1.6658207 | 7 | IL2RB;IL2RG;STAT5A;JAK3;IL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0178767 | 0.1814044 | 0.3524879 | 0.5936431 | 1.6612915 | 20 | TUBB2B;TUBB;TUBB3;TUBB6;ARHGEF2;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_CDKN1B_TO_P27_CELL_CYCLE_G1_S | 0.0145421 | 0.1612735 | 0.3807304 | 0.7617576 | 1.6606319 | 8 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT | 0.0184517 | 0.1842195 | 0.3524879 | 0.7920205 | 1.6559959 | 7 | CP;TF;STEAP3;SLC39A14;SLC11A2;TFRC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0083669 | 0.1259970 | 0.3807304 | 0.5260380 | 1.6495369 | 35 | PSMB2;APP;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 0.0163759 | 0.1747706 | 0.3524879 | 0.6104484 | 1.6447225 | 17 | FEN1;RFC2;RFC4;RFC5;PCNA;POLD1;POLE3;LIG1;RFC3;POLD2;POLD3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0474958 | 0.3230761 | 0.3217759 | 0.6543258 | 1.6432101 | 13 | MMP1;CCL2;CYBB;TNF;IL1B;ACE2;IL6;NFKB1;IL12A | non-significant |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 0.0220420 | 0.2006472 | 0.3524879 | 0.5870325 | 1.6427921 | 20 | NCAPD2;KIF4A;DNMT3B;TOP2A;NCAPG;PPP2R5D;NCAPD3;PPP2R5A;NCAPH;SMC4;NCAPG2 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0096460 | 0.1259970 | 0.3807304 | 0.5200416 | 1.6307333 | 35 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PRNP;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0122898 | 0.1435359 | 0.3807304 | 0.5066228 | 1.6206775 | 39 | PSMB2;PSMC4;PSMB6;PSMD11;VCP;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION | 0.0258602 | 0.2254576 | 0.3524879 | 0.6773965 | 1.6176607 | 11 | APH1A;NOTCH1;ADAM17;NCSTN;NOTCH2;PSENEN | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 0.0234092 | 0.2080923 | 0.3524879 | 0.5992778 | 1.6146258 | 17 | MYD88;TNF;IRAK1;IL6;NFKB1;IL12A;MAP3K7;IKBKG;RELA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCNE_TO_CELL_CYCLE_G1_S | 0.0213018 | 0.1997850 | 0.3524879 | 0.8106446 | 1.6117275 | 6 | CCNE1;E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 0.0334967 | 0.2591809 | 0.3217759 | 0.5695432 | 1.6041568 | 21 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.0298884 | 0.2461430 | 0.3524879 | 0.7352106 | 1.6027594 | 8 | PLCG2;LYN;SYK;BTK;BLNK | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0314140 | 0.2461430 | 0.3217759 | 0.6701263 | 1.6002991 | 11 | BID;APP;BAK1;FAS;BAX | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0312094 | 0.2461430 | 0.3524879 | 0.7329339 | 1.5977961 | 8 | BID;BAK1;BAX;CASP3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0392361 | 0.2891327 | 0.3217759 | 0.6034751 | 1.5962894 | 16 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 0.0346439 | 0.2647475 | 0.3217759 | 0.6191515 | 1.5948579 | 14 | CD19;LYN;CR2;SYK;PIK3CD;PIK3AP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_II_BLOOD_GROUP_ANTIGEN_BIOSYNTHESIS | 0.0390902 | 0.2891327 | 0.3217759 | 0.7573935 | 1.5835961 | 7 | B4GALT3;GCNT2;B4GALT1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0293934 | 0.2458722 | 0.3524879 | 0.5874149 | 1.5826638 | 17 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0279069 | 0.2399217 | 0.3524879 | 0.7954953 | 1.5816076 | 6 | FUT3;FUT4;FUT7;ST3GAL6 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY | 0.0417630 | 0.2937648 | 0.3217759 | 0.7541615 | 1.5768384 | 7 | CD40LG;RELB;CD40;NFKB2;TRAF2;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0145902 | 0.1612735 | 0.3807304 | 0.4954252 | 1.5736433 | 38 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0190952 | 0.1876183 | 0.3524879 | 0.4907196 | 1.5698033 | 39 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY | 0.0414864 | 0.2937648 | 0.3217759 | 0.7161670 | 1.5612442 | 8 | PLCG2;PRKCB;PRKCA;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE | 0.0414864 | 0.2937648 | 0.3217759 | 0.7155797 | 1.5599639 | 8 | MRAS;RAF1;BRAF;PPP1CA;PPP1CC;PPP1CB;ARAF | non-significant |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0606072 | 0.3572938 | 0.3217759 | 0.5875039 | 1.5376907 | 15 | FASLG;BID;BAK1;FAS;BAX;CASP10;TNFSF10;TNFRSF10B | non-significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_INNER_KINETOCHORE | 0.0514608 | 0.3388749 | 0.3217759 | 0.5903775 | 1.5207397 | 14 | CENPA;CENPW;CENPN;CENPI;CENPL;CENPO;CENPQ | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S | 0.0554256 | 0.3572938 | 0.3217759 | 0.7620298 | 1.5150714 | 6 | CDK6;E2F3;E2F2;E2F1;CDK4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0307107 | 0.2461430 | 0.3524879 | 0.4823646 | 1.5125867 | 35 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_INACTIVATION_OF_CONDENSIN_I | 0.0551876 | 0.3572938 | 0.2878571 | 0.7558635 | 1.5028115 | 6 | NCAPD2;NCAPG;NCAPH;SMC4;CSNK2A2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY | 0.0626398 | 0.3616280 | 0.2712886 | 0.5805180 | 1.4953428 | 14 | ARPC1B;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A;ABI1;WASF2;ARPC2;ACTG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.0600000 | 0.3572938 | 0.2765006 | 0.7149570 | 1.4948677 | 7 | C1QA;C1QB;C2;C1QC;C1S;C1R | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.0600000 | 0.3572938 | 0.2765006 | 0.7139520 | 1.4927665 | 7 | STAT1;STAT5A;STAT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.0722147 | 0.3887036 | 0.2878051 | 0.5273319 | 1.4852660 | 21 | CDC20;MAD2L2;PTTG2;BUB1B;PTTG1;MAD2L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 0.0588235 | 0.3572938 | 0.2878571 | 0.5497769 | 1.4812562 | 17 | CDC20;BUB1B;TRIP13;MAD2L1;MAD2L1BP;ANAPC5;CDC26 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 0.0451040 | 0.3102154 | 0.3217759 | 0.5064934 | 1.4738769 | 25 | EZH2;EHMT2;JARID2;TFDP1;EED;WDR5;AEBP2;PCGF6;HDAC2;RING1;L3MBTL2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0403454 | 0.2937648 | 0.3217759 | 0.4689809 | 1.4706185 | 35 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 0.0991088 | 0.4612656 | 0.2878051 | 0.6341455 | 1.4670751 | 10 | BIRC5;NFKB1;PIK3CD;MTOR;RELA;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 0.0635294 | 0.3616280 | 0.2765006 | 0.5268459 | 1.4631867 | 19 | PLCG2;PRKCB;PLCB4;CXCR4;MAPK1;RAF1;PLCB2;BRAF;PRKCA | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0435937 | 0.3031966 | 0.3217759 | 0.4844690 | 1.4513091 | 29 | NCKAP1L;CYTH4;ARPC1B;CYTH1;ACTR3;ACTB;ARPC5;ARPC5L;ARF1;ARPC1A;BRK1;PIK3CD;ABI1;PIK3CB;WASF1;WASF2;ARPC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_OKAZAKI_FRAGMENT_MATURATION | 0.0719258 | 0.3887036 | 0.2572065 | 0.6050914 | 1.4449921 | 11 | FEN1;DNA2;PCNA;POLD1;LIG1;RNASEH2A;POLD2;POLD3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY | 0.0894855 | 0.4344341 | 0.2249661 | 0.5588936 | 1.4396410 | 14 | ARPC1B;ACTR3;BAIAP2L1;ACTB;ARPC5;ARPC5L;ARPC1A | non-significant |
| KEGG_MEDICUS_REFERENCE_UREA_CYCLE | 0.0971302 | 0.4554820 | 0.2139279 | 0.7212979 | 1.4340881 | 6 | ASS1;ARG2;ARG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 0.0606061 | 0.3572938 | 0.2820134 | 0.4747360 | 1.4303891 | 31 | TUBB2B;TPX2;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A;HAUS8;HAUS6 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 0.0696056 | 0.3881608 | 0.2616635 | 0.5057347 | 1.4244359 | 21 | CHRM1;PLCB4;APP;CHRM3;PLCB2;VDAC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 0.0636792 | 0.3616280 | 0.2765006 | 0.4874132 | 1.4229789 | 26 | CCL5;CCR5;PRKCB;PLCB4;GNGT2;GNG5;PLCB2;GNGT1;PRKCA;GNG4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY | 0.0931818 | 0.4436888 | 0.2220560 | 0.5660628 | 1.4215550 | 13 | ARPC1B;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 0.0776471 | 0.4107994 | 0.2489111 | 0.5269454 | 1.4197414 | 17 | MAP2K3;MYD88;IL1B;IRAK1;MAP2K6;MAP3K7;IL1RAP;ZFP36 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOD_NFKB_SIGNALING_PATHWAY | 0.0969163 | 0.4554820 | 0.2139279 | 0.6248808 | 1.4144545 | 9 | RIPK2;NOD1;NFKB1;NOD2;IKBKG;RELA;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 0.0660377 | 0.3716123 | 0.2712886 | 0.4839423 | 1.4128457 | 26 | EXO1;RFC2;RFC4;RPA2;RFC5;PCNA;POLD1;POLE3;MSH2;RPA1;LIG1;MSH6;RFC3;POLD2;POLD3;PMS1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 0.0776471 | 0.4107994 | 0.2489111 | 0.5240950 | 1.4120616 | 17 | TNF;APP;NRAS;MAPK1;RAF1;IL6;NFKB1;BRAF;RELA | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 0.0707547 | 0.3887036 | 0.2616635 | 0.4823824 | 1.4082916 | 26 | TUBB2B;TPX2;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A;CKAP5;TUBB4A | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH | 0.1169978 | 0.5097167 | 0.1938133 | 0.7063970 | 1.4044620 | 6 | C1S;C1R;SERPING1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AHR_SIGNALING_PATHWAY | 0.1037528 | 0.4695639 | 0.2065879 | 0.6440727 | 1.4040787 | 8 | CYP1B1;VEGFA;IL6;PTGS2;AHR | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.0847059 | 0.4250380 | 0.2377938 | 0.5191478 | 1.3987324 | 17 | PLCG2;LYN;SYK;BTK;NFATC3;PPP3CC;BLNK;CALM3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 0.0835267 | 0.4250380 | 0.2377938 | 0.4957550 | 1.3963273 | 21 | NCK1;NCK2;ARPC1B;WIPF1;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0567816 | 0.3572938 | 0.3217759 | 0.4333070 | 1.3917127 | 40 | PSMB2;PSMC4;PSMB6;PSMD11;PSMC2;PSMB4;PSMA8;PSMD7;PSMA5;PSMA4;PSMD8;PSMD2;PSMD6;PSMD13;ADRM1;PSMD14;PSMC3;PSMD1;PSMD12;PSMA2;PSMB5;PSMB3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.1236203 | 0.5101398 | 0.1882041 | 0.6991501 | 1.3900536 | 6 | MAP2K3;MAP2K6;MAP2K7;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MODIFYING_OF_CONDENSIN_II_SUBUNITS | 0.1236203 | 0.5101398 | 0.1882041 | 0.6989364 | 1.3896287 | 6 | PLK1;CDK1;AURKB;NCAPD3;NCAPG2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 0.0898345 | 0.4344341 | 0.2311267 | 0.4893451 | 1.3824612 | 22 | GSTA5;GSTA1;GSTA2;GSTP1;MGST1;CYP1B1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 0.1189427 | 0.5101398 | 0.1918922 | 0.6079968 | 1.3762366 | 9 | PDCD1;CD274;PTPN6;PIK3CD;PDCD1LG2;PIK3R3 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.1449893 | 0.5624174 | 0.1695706 | 0.7178632 | 1.3753978 | 5 | FUT3;FUT4;FUT9 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 0.1202673 | 0.5101398 | 0.1918922 | 0.5245622 | 1.3729515 | 15 | PLK1;CDK1;CDCA5;AURKB;PPP2R5D;PPP2R5A;STAG1;PPP2R1A | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.1039261 | 0.4695639 | 0.2114002 | 0.5177546 | 1.3695447 | 16 | CYBA;NCF1;NCF4;CYBB;RAC2;NCF2;PRNP;FYN;PIK3CD | non-significant |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0906977 | 0.4352082 | 0.2279872 | 0.4680450 | 1.3619933 | 25 | CYTH4;ARPC1B;CYTH1;ACTR3;ACTB;ARPC5;ARPC5L;ARF1;ARPC1A;BRK1;ABI1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 0.1079812 | 0.4808660 | 0.2089550 | 0.4970344 | 1.3604824 | 18 | GSTA5;GSTA1;GSTA2;GSTP1;MGST1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.0813953 | 0.4250380 | 0.2413400 | 0.4510249 | 1.3555183 | 30 | CYTH4;ARPC1B;CYTH1;ACTR3;ACTB;ARPC5;ARPC5L;PIK3CG;ARF1;ARPC1A;BRK1;PIK3CD;ABI1;PIK3CB;WASF1;WASF2;ARPC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0867580 | 0.4296256 | 0.2311267 | 0.4523325 | 1.3550390 | 29 | CYBA;NCF1;NCF4;CREB3L2;CYBB;RAC2;MAPK1;NCF2;CREB3;PRNP;FYN;ATF4;PIK3CD | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_ | 0.1393805 | 0.5460541 | 0.1766943 | 0.8210419 | 1.3528054 | 3 | AMY1C;MGAM | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.1355556 | 0.5376375 | 0.1797823 | 0.6459538 | 1.3505923 | 7 | STAT1;VEGFA;STAT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066 | 0.1363636 | 0.5376375 | 0.1813831 | 0.5348164 | 1.3430858 | 13 | CDKN2A;CDK6;E2F3;E2F2;E2F1;CCND2 | non-significant |
| KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S | 0.1307339 | 0.5289171 | 0.1864326 | 0.5796382 | 1.3409742 | 10 | CDKN2A;CDK6;E2F3;E2F2;E2F1;CCND2 | non-significant |
| KEGG_MEDICUS_VARIANT_DAB1_OVEREXPRESSION_TO_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.1453744 | 0.5624174 | 0.1723243 | 0.5907121 | 1.3371118 | 9 | VLDLR;PIK3CD;PIK3CB;DAB1;AKT2;AKT1;PIK3CA;RELN | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS | 0.1641791 | 0.6030484 | 0.1585141 | 0.6977279 | 1.3368193 | 5 | B3GNT5;B3GALT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.1334842 | 0.5330755 | 0.1830239 | 0.5388414 | 1.3316805 | 12 | CCR5;CXCR4;PIK3CD;GNAI1;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY | 0.1488889 | 0.5682789 | 0.1709323 | 0.6318519 | 1.3211074 | 7 | FASLG;FAS;DAXX | non-significant |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 0.1229698 | 0.5101398 | 0.1938133 | 0.4715957 | 1.3197459 | 20 | CHRM1;PLCB4;CHRM3;PLCB2;VDAC3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_CELL_CYCLE_G1_S | 0.1876380 | 0.6381753 | 0.1501698 | 0.6601948 | 1.3126025 | 6 | E2F3;E2F2;E2F1;RBL1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1252955 | 0.5102495 | 0.1938133 | 0.4635378 | 1.3095523 | 22 | TUBB2B;TUBB;TUBB3;TUBB6;APP;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA2_TO_RBP_JK_MEDIATED_TRANSCRIPTION | 0.1688889 | 0.6042903 | 0.1596467 | 0.6258696 | 1.3085994 | 7 | RUNX3;CR2;MYC | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY | 0.1636364 | 0.6030484 | 0.1644058 | 0.5166638 | 1.2974991 | 13 | ARPC1B;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A;SRC;ARPC2;ACTG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 0.1496437 | 0.5682789 | 0.1766943 | 0.4486705 | 1.2932594 | 24 | MAP2K3;CREB3L2;TNF;MAP2K6;TRADD;CREB3;MAP3K7;RPS6KA4;ATF4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 0.1600928 | 0.5969726 | 0.1682382 | 0.4607316 | 1.2893430 | 20 | ARPC1B;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A;BRK1;ABI1;WASF1;WASF2;ARPC2;ACTG1 | non-significant |
| KEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION | 0.1508121 | 0.5692236 | 0.1737478 | 0.5396205 | 1.2886440 | 11 | GZMB;DEFA3;HDAC2;MPO;CSF2;ELANE | non-significant |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 0.1824480 | 0.6274185 | 0.1563124 | 0.4853061 | 1.2837133 | 16 | TNF;NRAS;MAPK1;RAF1;IL6;NFKB1;BRAF;RELA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_REL_TO_TRANSCRIPTION | 0.1810155 | 0.6259696 | 0.1531588 | 0.5849818 | 1.2752604 | 8 | BIRC3;BCL2A1;TRAF1;CD40;CCND2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY | 0.1740139 | 0.6155121 | 0.1608014 | 0.5287711 | 1.2627350 | 11 | TRADD;NFKB1;MAP3K7;IKBKG;RELA;CHUK;NFKBIA;TAB1;TRAF6;TAB2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_II | 0.2406181 | 0.7373396 | 0.1307771 | 0.6341090 | 1.2607386 | 6 | SDHA;SDHD;SDHC;GSTO1;SDHB;AS3MT | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.2406181 | 0.7373396 | 0.1307771 | 0.6338497 | 1.2602230 | 6 | TCF7L1;TCF7;MYC | non-significant |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 0.1674528 | 0.6030484 | 0.1656567 | 0.4413625 | 1.2601136 | 23 | GSTA5;GSTA1;GSTA2;GSTP1;MGST1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_E2_TO_NOD_NFKB_SIGNALING_PATHWAY | 0.2048458 | 0.6854030 | 0.1429011 | 0.5559805 | 1.2584946 | 9 | RIPK2;NOD1;NFKB1;IKBKG;RELA;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 0.1491841 | 0.5682789 | 0.1752040 | 0.4144355 | 1.2487023 | 31 | EZH2;JARID2;PHF19;CBX2;MTF2;EED;AEBP2;PHC2;SCMH1;RING1;SCML2;PHF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 0.2158590 | 0.7032460 | 0.1388051 | 0.5508438 | 1.2468674 | 9 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;TGFA;PIK3CA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.1971831 | 0.6633497 | 0.1511488 | 0.4540612 | 1.2428562 | 18 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 0.2093541 | 0.6929957 | 0.1420566 | 0.4746528 | 1.2423223 | 15 | CDK6;E2F3;E2F2;E2F1;CCND2;ATM;ATR | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.2147806 | 0.7032460 | 0.1429011 | 0.4655433 | 1.2314375 | 16 | CDC20;PTTG2;PTTG1;ANAPC5;CDC26;ESPL1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY | 0.2217195 | 0.7111106 | 0.1388051 | 0.4946321 | 1.2224227 | 12 | CCL2;BIRC3;NFKB1;BIRC2;IKBKG;RELA;TRAF2;TNFRSF14;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.2276995 | 0.7254293 | 0.1395997 | 0.4437940 | 1.2147527 | 18 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A;GSK3B;TUBB4A | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY | 0.2330317 | 0.7254293 | 0.1350020 | 0.4885180 | 1.2073122 | 12 | PRKCB;PLCB4;PLCB2;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS | 0.2330317 | 0.7254293 | 0.1350020 | 0.4861042 | 1.2013469 | 12 | IDO1;TDO2;IDO2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS | 0.2891832 | 0.7872319 | 0.1177658 | 0.5963122 | 1.1855909 | 6 | B3GNT5;B4GALT3;B4GALT1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.2304038 | 0.7254293 | 0.1395997 | 0.4109667 | 1.1845808 | 24 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;PLEKHM2;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY | 0.2683486 | 0.7783700 | 0.1256399 | 0.5112025 | 1.1826504 | 10 | PRKCB;PLCB4;PLCB2;PRKCA | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE | 0.2891832 | 0.7872319 | 0.1177658 | 0.5940783 | 1.1811494 | 6 | FCN1;FCN3;COLEC11 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 0.2393736 | 0.7373396 | 0.1321473 | 0.3928882 | 1.1794227 | 28 | SFRP1;WNT6;WIF1;WNT10A;WNT5B;TRABD2A | non-significant |
| KEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.2541667 | 0.7674593 | 0.1226792 | 0.8953608 | 1.1790260 | 1 | CCND2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.2847682 | 0.7872319 | 0.1188150 | 0.5399777 | 1.1771514 | 8 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 0.2605634 | 0.7733698 | 0.1294429 | 0.4281051 | 1.1718090 | 18 | STAT1;IFNAR2;TYK2;STAT2;IFNB1;EIF2AK2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_K15_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.2891832 | 0.7872319 | 0.1177658 | 0.5344016 | 1.1649957 | 8 | NFKB1;MAP3K7;IKBKG;RELA;TRAF2;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2623318 | 0.7733698 | 0.1256399 | 0.3905187 | 1.1630540 | 27 | IL27RA;STAT1;IL27;JAK2;STAT3;IL13;IL6;OSM;TYK2;IL6R | non-significant |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 0.2443946 | 0.7415699 | 0.1307771 | 0.3749026 | 1.1613301 | 33 | CLDN4;CLDN3;ARPC1B;CLDN10;ACTR3;ACTB;ARPC5;ARPC5L;ARPC1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 0.2935982 | 0.7872319 | 0.1167392 | 0.5319027 | 1.1595480 | 8 | KIT;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 0.2783964 | 0.7872319 | 0.1209851 | 0.4425685 | 1.1583472 | 15 | PRKD3;PRKD2;NFKB1;IKBKG;RELA;SRC;ACP1;CHUK;PTPN11;NFKBIA;ABL2;PTPRJ;ABL1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 0.2847059 | 0.7872319 | 0.1232572 | 0.4282609 | 1.1538573 | 17 | PLCG2;CCR5;CXCR4;NFATC3;PPP3CC;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.3289183 | 0.8261482 | 0.1092500 | 0.5773679 | 1.1479256 | 6 | HK3;BAX | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2729412 | 0.7827886 | 0.1262540 | 0.4128292 | 1.1465329 | 19 | STAT1;IFNAR2;TYK2;STAT2;IFNB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN | 0.3200883 | 0.8236170 | 0.1110115 | 0.5244453 | 1.1432908 | 8 | FCN1;FCN3;COLEC11 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.2735849 | 0.7827886 | 0.1262540 | 0.3911985 | 1.1420847 | 26 | MAP2K3;MYD88;TLR2;IRAK1;MAPK1;MAP2K6;MAP3K7;MAPK13 | non-significant |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.2744186 | 0.7827886 | 0.1250334 | 0.3760249 | 1.1301120 | 30 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;PLEKHM2;TUBA4A | non-significant |
| KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.3333333 | 0.8261482 | 0.1083943 | 0.5170310 | 1.1271276 | 8 | PIK3CD;PIK3CB;AKT2;AKT1;TGFA;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.3159091 | 0.8236170 | 0.1137873 | 0.4487328 | 1.1269038 | 13 | PRKCB;PLCB4;PLCB2;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 0.2948113 | 0.7872319 | 0.1209851 | 0.3946887 | 1.1268576 | 23 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P15_CELL_CYCLE_G1_S | 0.3386364 | 0.8261482 | 0.1092500 | 0.4432583 | 1.1131558 | 13 | CDK6;E2F3;E2F2;E2F1;CCND2;MYC;CCND3;ZBTB17;CDK4;CDKN2B | non-significant |
| KEGG_MEDICUS_VARIANT_DELETED_DMD_TO_DYSTROPHIN_ASSOCIATED_PROTEIN_COMPLEX | 0.3394495 | 0.8261482 | 0.1096841 | 0.4800787 | 1.1106466 | 10 | ACTB;DMD;DAG1;SNTB1;SNTG2;SNTA1;ACTG1;DTNA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S | 0.3573086 | 0.8386418 | 0.1071402 | 0.4647942 | 1.1099545 | 11 | CDK6;E2F3;E2F2;E2F1;CCND2;MYC;CCND3;CDK4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.3487859 | 0.8335848 | 0.1055209 | 0.5086621 | 1.1088835 | 8 | PRKCB;CRK;PTK2B;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 0.3664459 | 0.8432343 | 0.1024494 | 0.5564549 | 1.1063464 | 6 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY | 0.3417431 | 0.8261482 | 0.1092500 | 0.4759345 | 1.1010590 | 10 | NFKB1;MAP3K7;IKBKG;RELA;CHUK;NFKBIA;TRAF6 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY | 0.3590308 | 0.8386418 | 0.1035763 | 0.4850334 | 1.0979017 | 9 | CDC25A;E2F1;RAF1;BIRC5;SRC | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY | 0.3325792 | 0.8261482 | 0.1101223 | 0.4437980 | 1.0967923 | 12 | PRKCB;MAPK1;RAF1;BRAF;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 0.3027523 | 0.8008704 | 0.1172497 | 0.3587687 | 1.0959779 | 32 | RAD54L;RFC2;RFC4;RPA2;RFC5;PCNA;POLD1;RAD51;POLE3;RPA1;RFC3;POLD2;POLD3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3206651 | 0.8236170 | 0.1157344 | 0.3801896 | 1.0958681 | 24 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 0.3443396 | 0.8261482 | 0.1105647 | 0.3818500 | 1.0902023 | 23 | LDHB;PFKP;ENO1;GAPDH | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.3310023 | 0.8261482 | 0.1123785 | 0.3607683 | 1.0870021 | 31 | CCL2;CCR2;GNGT2;GNG5;NFKB1;PIK3CD;GNGT1;IKBKG;GNG4;RELA;PIK3CB;AKT2;AKT1;GNG7;GNB3;PIK3CA;CHUK;GNB4;NFKBIA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3534884 | 0.8383498 | 0.1079724 | 0.3733080 | 1.0863123 | 25 | TUBB2B;TUBB;TUBB3;TUBB6;TUBB2A;TUBA1C;TUBA1A;TUBA4A | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.3410673 | 0.8261482 | 0.1101223 | 0.3848317 | 1.0839044 | 21 | PLCG2;PLCB4;CXCR4;PLCB2;NFATC3;PPP3CC | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.3443396 | 0.8261482 | 0.1105647 | 0.3705694 | 1.0818590 | 26 | CCR5;CXCR4;RAC2;GNGT2;GNG5;LIMK1;PAK1;GNGT1;CFL1;GNG4 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.3810573 | 0.8594720 | 0.0999277 | 0.4777993 | 1.0815268 | 9 | MET;PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S | 0.3876652 | 0.8594720 | 0.0988903 | 0.4757491 | 1.0768861 | 9 | CDK6;E2F3;E2F2;E2F1;CCND2;CCND3;CDK4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 0.3876652 | 0.8594720 | 0.0988903 | 0.4740276 | 1.0729894 | 9 | NRAS;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.3566434 | 0.8386418 | 0.1075544 | 0.3545697 | 1.0683254 | 31 | PRKCB;PLCB4;CXCR4;GNGT2;GNG5;PLCB2;CRK;PTK2B;GNGT1;PRKCA;GNG4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 0.3929412 | 0.8594720 | 0.1020801 | 0.3950738 | 1.0644417 | 17 | MYD88;TLR8;IRAK1;TLR9;IFNB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.4039735 | 0.8730330 | 0.0965630 | 0.4869165 | 1.0614780 | 8 | MMP9;VCAM1;CYBB;IL6;NFKB1;RELA | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 0.3781903 | 0.8594720 | 0.1035763 | 0.3787612 | 1.0599514 | 20 | CREB3L2;NRAS;MAPK1;RAF1;CREB3;ATF4;BRAF | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S | 0.3891403 | 0.8594720 | 0.1002791 | 0.4263029 | 1.0535555 | 12 | CDK6;E2F3;E2F2;E2F1;CCND2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.3892617 | 0.8594720 | 0.0995791 | 0.4061940 | 1.0463055 | 14 | PLCG2;PRKCB;MAPK1;RAF1;BRAF;PRKCA;PLCG1 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.3914989 | 0.8594720 | 0.0992333 | 0.4052044 | 1.0437565 | 14 | PLCG2;PRKCB;MAPK1;RAF1;BRAF;PRKCA;PLCG1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.4266667 | 0.9074630 | 0.0937465 | 0.4986793 | 1.0426636 | 7 | NFKB1;IKBKG;RELA;TRAF2;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55 | 0.4392324 | 0.9088860 | 0.0897105 | 0.5402304 | 1.0350604 | 5 | GORASP2;MAP1LC3B;LAMP2;MAP1LC3A | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST | 0.4431555 | 0.9088860 | 0.0940503 | 0.4264296 | 1.0183377 | 11 | DDOST;RPN1;TUSC3;ALG6;STT3A | non-significant |
| KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY | 0.4357798 | 0.9088860 | 0.0943564 | 0.4391060 | 1.0158575 | 10 | MAPK1;RAF1;PAK1;BRAF;ARAF;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.4410377 | 0.9088860 | 0.0952880 | 0.3225562 | 1.0149181 | 37 | WNT6;TCF7L1;WNT10A;FZD7;TCF7;LRP6;WNT5B;FRAT2;MYC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4340045 | 0.9088860 | 0.0931455 | 0.3915719 | 1.0086410 | 14 | KIT;NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 0.4411085 | 0.9088860 | 0.0940503 | 0.3804805 | 1.0064327 | 16 | CDC20;PTTG1;ANAPC5;CDC26;ESPL1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_REPRESSION | 0.4768212 | 0.9460010 | 0.0870516 | 0.5029431 | 0.9999540 | 6 | MYCN;ZBTB17;NTRK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY | 0.4840909 | 0.9512771 | 0.0878313 | 0.3940071 | 0.9894710 | 13 | MAPK1;RAF1;BRAF;YWHAQ;YWHAH;ARAF;MAP2K1;MAP2K2;YWHAE;YWHAG | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.4885321 | 0.9547389 | 0.0878313 | 0.4261220 | 0.9858194 | 10 | FCN1;C2;FCN3;COLEC11 | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.5104408 | 0.9547389 | 0.0860347 | 0.4099004 | 0.9788651 | 11 | CRK;PIK3CD;CBL;PIK3CB;AKT2;AKT1;PIK3CA;ABL1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 0.5099338 | 0.9547389 | 0.0833634 | 0.4482767 | 0.9772433 | 8 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 0.5174014 | 0.9547389 | 0.0852885 | 0.4082016 | 0.9748082 | 11 | RYR1;RYR3;CACNA1E;CALM3;CACNA1A | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.5165563 | 0.9547389 | 0.0826646 | 0.4468092 | 0.9740441 | 8 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA;ALK | non-significant |
| KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY | 0.5066667 | 0.9547389 | 0.0840746 | 0.4655518 | 0.9733988 | 7 | PLCB4;PLCB2 | non-significant |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.5214286 | 0.9547389 | 0.0862866 | 0.2971129 | 0.9726548 | 45 | WNT6;TCF7L1;FZD9;WNT10A;FZD7;TCF7;LRP6;WNT5B;FRAT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 0.5070423 | 0.9547389 | 0.0870516 | 0.3545559 | 0.9704902 | 18 | GAR1;CCT4;RUVBL1;DKC1;CCT6A;RUVBL2;WRAP53;CCT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 0.5213270 | 0.9547389 | 0.0860347 | 0.2939923 | 0.9695959 | 46 | WNT6;TCF7L1;FZD9;WNT10A;FZD7;TCF7;LRP6;WNT5B;FRAT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 0.5035294 | 0.9547389 | 0.0875697 | 0.3485933 | 0.9681333 | 19 | WNT6;WNT10A;WNT5B | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 0.5055679 | 0.9547389 | 0.0843144 | 0.3668626 | 0.9602000 | 15 | NRAS;MAPK1;RAF1;FLT3LG;BRAF | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_NFKB_SIGNALING_PATHWAY | 0.5187638 | 0.9547389 | 0.0824344 | 0.4808852 | 0.9560982 | 6 | NFKB1;IKBKG;RELA;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.4966443 | 0.9547389 | 0.0855357 | 0.3706500 | 0.9547487 | 14 | PLCG2;CAMK1D;CALM3;CAMK2D;PLCG1;CAMK2G;CAMK1G;CAMK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 0.5313225 | 0.9644828 | 0.0838361 | 0.3406786 | 0.9533784 | 20 | TRIM27;EZH2;JARID2;EED;AEBP2;KDM2B;RING1;PCGF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 0.5189310 | 0.9547389 | 0.0828962 | 0.3633961 | 0.9511270 | 15 | PLCG2;PRKCB;MAPK1;RAF1;BRAF;PRKCA;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_PI3K_SIGNALING_PATHWAY | 0.5366972 | 0.9672239 | 0.0826646 | 0.4110894 | 0.9510421 | 10 | PIK3CD;GNAI1;PIK3CB;AKT2;AKT1;PIK3CA;ADRB2;GNAI2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 0.5400943 | 0.9672239 | 0.0838361 | 0.3314851 | 0.9464078 | 23 | ITGB8;ITGB7;ITGA9 | non-significant |
| KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY | 0.5055928 | 0.9547389 | 0.0845557 | 0.3670659 | 0.9455164 | 14 | RRAGD;SLC7A5;SLC3A2;MTOR;RRAGC | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_RASSF1_TO_RAS_RASSF1_SIGNALING_PATHWAY | 0.5430464 | 0.9672239 | 0.0799859 | 0.4720801 | 0.9385919 | 6 | NRAS;RASSF5;STK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 0.5511628 | 0.9677562 | 0.0819779 | 0.3118860 | 0.9373477 | 30 | CCL2;CCL4;CCL3;GNGT2;GNG5;PIK3CG;GNGT1;CCL1;GNG4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.5518868 | 0.9677562 | 0.0826646 | 0.3272553 | 0.9343314 | 23 | ITGB8;ITGB7;ITGA9 | non-significant |
| KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 0.5484581 | 0.9672239 | 0.0793435 | 0.4117487 | 0.9320176 | 9 | ICOS;PIK3CD;PIK3R3;AKT2;AKT1 | non-significant |
| KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5234899 | 0.9547389 | 0.0826646 | 0.3610712 | 0.9300748 | 14 | NRAS;MAPK1;RAF1;BRAF;MET | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 0.5478842 | 0.9672239 | 0.0799859 | 0.3552977 | 0.9299308 | 15 | MYD88;IRAK1;TLR9;IFNB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS | 0.5591647 | 0.9732704 | 0.0810802 | 0.3891197 | 0.9292397 | 11 | ACSL1;ACSL5;ACSL6;ACSL4 | non-significant |
| KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5614849 | 0.9732704 | 0.0808589 | 0.3881847 | 0.9270068 | 11 | NRAS;MAPK1;RAF1;BRAF;ARAF;MAP2K1;MAP2K2;NTRK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS | 0.5849890 | 0.9732704 | 0.0760837 | 0.4229492 | 0.9220293 | 8 | CHST3;CSGALNACT1;CHPF2;CHSY1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 0.5788235 | 0.9732704 | 0.0799859 | 0.3278059 | 0.9104013 | 19 | IFIH1;TANK;IKBKE;IRF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 0.5966981 | 0.9732704 | 0.0785029 | 0.3099126 | 0.9047747 | 26 | ITGB8;ITGB7;ITGA9 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6037736 | 0.9732704 | 0.0778840 | 0.3072280 | 0.8969370 | 26 | PROM1;HOXA10;MEF2C | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS | 0.6215596 | 0.9760617 | 0.0749279 | 0.3855588 | 0.8919777 | 10 | SHC4;PTPN11 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.5838926 | 0.9732704 | 0.0768737 | 0.3461303 | 0.8915889 | 14 | PLCG2;CAMK1D;CALM3;CAMK2D;PLCG1;CAMK2G;CAMK1G;CAMK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.5968820 | 0.9732704 | 0.0755015 | 0.3402174 | 0.8904607 | 15 | VLDLR;PIK3CD;MTOR;PIK3CB;DAB1;AKT2;AKT1;RHEB;PIK3CA;RELN | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 0.6013363 | 0.9732704 | 0.0751182 | 0.3391750 | 0.8877325 | 15 | NRAS;MAPK1;RAF1;PTK2B;BRAF;SRC;ARAF;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.6114790 | 0.9760617 | 0.0738053 | 0.4065353 | 0.8862470 | 8 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6164706 | 0.9760617 | 0.0766747 | 0.3181518 | 0.8835894 | 19 | RYR1;PRNP;RYR3;VDAC3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.5970149 | 0.9732704 | 0.0732559 | 0.4608230 | 0.8829189 | 5 | BAX;CASP3;APAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.5950783 | 0.9732704 | 0.0758887 | 0.3415872 | 0.8798864 | 14 | NFKB1;PIK3CD;IKBKG;RELA;PIK3CB;AKT2;AKT1;PIK3CA;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6359338 | 0.9760617 | 0.0753094 | 0.3099915 | 0.8757648 | 22 | PLCB4;APP;PLCB2;VDAC3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S | 0.6247241 | 0.9760617 | 0.0727141 | 0.4015446 | 0.8753673 | 8 | E2F3;E2F2;E2F1;CCND2;CCND3;CDK4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION | 0.6266968 | 0.9760617 | 0.0738053 | 0.3534851 | 0.8735951 | 12 | CREB3L2;PCNA;CREB3;ATF4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 0.6806527 | 0.9760617 | 0.0711327 | 0.2890456 | 0.8709000 | 31 | VEGFA;NRAS;MAPK1;GNGT2;GNG5;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.6289593 | 0.9760617 | 0.0736213 | 0.3513267 | 0.8682608 | 12 | PRKCB;PLCB4;PLCB2;PRKCA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS | 0.6355556 | 0.9760617 | 0.0721798 | 0.4830384 | 0.8663729 | 4 | HSD11B1;CBR1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.6335541 | 0.9760617 | 0.0720033 | 0.4353397 | 0.8655445 | 6 | PLCB4;PLCB2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY | 0.6425339 | 0.9760617 | 0.0725352 | 0.3467406 | 0.8569269 | 12 | TNF;NFKB1;RELA;IFNB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_SECOND_CARBON_OXIDATION_2 | 0.6720183 | 0.9760617 | 0.0709609 | 0.3703834 | 0.8568699 | 10 | MDH2;FH;SDHA;SDHD;SUCLG1;MDH1;SDHC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.6497797 | 0.9760617 | 0.0706196 | 0.3780651 | 0.8557727 | 9 | MET;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 0.6658933 | 0.9760617 | 0.0720033 | 0.3052326 | 0.8541837 | 20 | PTPN7;DUSP2;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 0.6581986 | 0.9760617 | 0.0723571 | 0.3219762 | 0.8516792 | 16 | TNF;TRADD;NFKB1;MAP3K7;IKBKG;RELA;TRAF2;RIPK1;CHUK;NFKBIA;TAB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP | 0.6585903 | 0.9760617 | 0.0699459 | 0.3747691 | 0.8483119 | 9 | PNP;NT5C2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.6774942 | 0.9760617 | 0.0711327 | 0.3009068 | 0.8475243 | 21 | PRKCB;PLCB4;MAPK1;RAF1;PLCB2;GNRH1;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION | 0.6834862 | 0.9760617 | 0.0701132 | 0.3660543 | 0.8468549 | 10 | DNMT3B;MAT1A;DNMT1;AHCY;DNMT3A | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.7162791 | 0.9797159 | 0.0684715 | 0.2815485 | 0.8461707 | 30 | ITGB8;ITGB7;ITGA9;ACTN4;ACTB;ITGB4 | non-significant |
| KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY | 0.6857798 | 0.9760617 | 0.0699459 | 0.3648819 | 0.8441424 | 10 | MAPK1;RAF1;MYC;BRAF;ARAF;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MEVALONATE_PATHWAY | 0.6742081 | 0.9760617 | 0.0701132 | 0.3412133 | 0.8432669 | 12 | ACAT2;MVD;HMGCS1;FDPS;IDI1 | non-significant |
| KEGG_MEDICUS_VARIANT_TMPRSS2_ERG_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6644444 | 0.9760617 | 0.0699459 | 0.4026574 | 0.8418962 | 7 | MMP9;IL1R2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6857798 | 0.9760617 | 0.0699459 | 0.3635245 | 0.8410021 | 10 | PLCB4;PLCB2;SPTBN2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GRM1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6718062 | 0.9760617 | 0.0689567 | 0.3705569 | 0.8387774 | 9 | PLCB4;PLCB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP | 0.6718062 | 0.9760617 | 0.0689567 | 0.3695001 | 0.8363852 | 9 | PNP;NT5C2;HPRT1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 0.6983759 | 0.9760617 | 0.0696133 | 0.3501993 | 0.8362955 | 11 | PIK3CD;GNAI1;PIK3CB;AKT2;AKT1;PIK3CA;ADRB2;GNAI2 | non-significant |
| KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.6926606 | 0.9760617 | 0.0694481 | 0.3611502 | 0.8355093 | 10 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_LIGHT_HVEM_NFKB_SIGNALING_PATHWAY | 0.6972477 | 0.9760617 | 0.0691198 | 0.3597230 | 0.8322074 | 10 | TNFSF14;NFKB1;IKBKG;RELA;TRAF2;TNFRSF14;CHUK;NFKBIA | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR4_IRF3_7_SIGNALING_PATHWAY | 0.6821192 | 0.9760617 | 0.0683111 | 0.3809354 | 0.8304393 | 8 | IKBKE;IRF3;IFNB1;TLR4 | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6823266 | 0.9760617 | 0.0689567 | 0.3222593 | 0.8301001 | 14 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 0.7613365 | 0.9880170 | 0.0667426 | 0.2570145 | 0.8299875 | 41 | TUBB2B;TUBB;TUBB3;TUBB6;OSBPL1A;TUBB2A;TUBA1C;TUBA1A;RILP;TUBA4A;ACTR1A;TUBB4A;DCTN3;DYNLL1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048 | 0.6822222 | 0.9760617 | 0.0686326 | 0.3964082 | 0.8288300 | 7 | HTRA2;TRAP1;CASP3;APAF1;CASP9;PINK1;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING | 0.6886364 | 0.9760617 | 0.0692836 | 0.3300234 | 0.8287887 | 13 | RIF1;PRKDC;DCLRE1C;XRCC6 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.7169811 | 0.9797159 | 0.0691198 | 0.2831521 | 0.8266486 | 26 | CXCR4;RAC2;GNGT2;GNG5;LIMK1;PAK1;GNGT1;CFL1;GNG4 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.7104072 | 0.9786298 | 0.0675189 | 0.3317023 | 0.8197615 | 12 | CXCR4;PIK3CD;GNAI1;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY | 0.7238979 | 0.9812475 | 0.0678338 | 0.3422903 | 0.8174085 | 11 | PRKCB;PLCB4;PLCB2;PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.7048458 | 0.9760617 | 0.0665892 | 0.3603798 | 0.8157409 | 9 | MAPK1;PROK2;GNAI1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.6843267 | 0.9760617 | 0.0681513 | 0.3741763 | 0.8157044 | 8 | MAPK1;PROK2;GNAI1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.7720930 | 0.9880170 | 0.0647943 | 0.2714053 | 0.8156863 | 30 | GNGT2;GNG5;IL6;NFKB1;PIK3CD;GNGT1;IKBKG;GNG4;RELA;PIK3CB;AKT2;AKT1;GNG7;GNB3;PIK3CA;CHUK;GNB4;NFKBIA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_ITPR1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.6911111 | 0.9760617 | 0.0679923 | 0.3900450 | 0.8155255 | 7 | PLCB4;PLCB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP | 0.6843267 | 0.9760617 | 0.0681513 | 0.3731262 | 0.8134152 | 8 | RASAL1;NRAS;RASA2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7046980 | 0.9760617 | 0.0673624 | 0.3154991 | 0.8126867 | 14 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7046980 | 0.9760617 | 0.0673624 | 0.3154183 | 0.8124785 | 14 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 0.7294118 | 0.9812475 | 0.0681513 | 0.2921946 | 0.8114996 | 19 | MYD88;IL1B;IRAK1;MAP3K7;MAP2K7;IL1RAP | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 0.7297921 | 0.9812475 | 0.0672065 | 0.3067340 | 0.8113613 | 16 | PPP2R2B;PPP2R5D;PPP2R3A;PPP2R3B;PPP2R5A;PPP2R1A;PPP2R2A | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.7230047 | 0.9812475 | 0.0684715 | 0.2961599 | 0.8106486 | 18 | PLCB4;PLCB2;NFATC3;PPP3CC;PTGS2;CALM3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.6931567 | 0.9760617 | 0.0675189 | 0.3706926 | 0.8081101 | 8 | MAPK1;PROK2;GNAI1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.7378190 | 0.9864146 | 0.0668966 | 0.3373500 | 0.8056107 | 11 | PLCB4;PLCB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY | 0.7000000 | 0.9760617 | 0.0673624 | 0.3851698 | 0.8053322 | 7 | STAT5A;JAK2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 0.7483296 | 0.9880170 | 0.0642141 | 0.3053883 | 0.7993014 | 15 | NRAS;MAPK1;RAF1;BRAF;MET | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCND1_TO_CELL_CYCLE_G1_S | 0.7041943 | 0.9760617 | 0.0667426 | 0.4001260 | 0.7955325 | 6 | E2F3;E2F2;E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.7594655 | 0.9880170 | 0.0635008 | 0.3038564 | 0.7952921 | 15 | NRAS;MAPK1;RAF1;BRAF;ARAF;MAP2K1;MAP2K2;TGFA | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 0.7616927 | 0.9880170 | 0.0633597 | 0.3023023 | 0.7912244 | 15 | NRAS;FLT3LG;PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.7616927 | 0.9880170 | 0.0633597 | 0.3019611 | 0.7903314 | 15 | PLCG2;CAMK1D;CALM3;CAMK2D;PLCG1;CAMK2G;CAMK1G;CAMK4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7616927 | 0.9880170 | 0.0633597 | 0.3017812 | 0.7898605 | 15 | NRAS;MAPK1;RAF1;BRAF;SRC;ARAF;MAP2K1;MAP2K2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050 | 0.7130243 | 0.9786298 | 0.0661326 | 0.3963856 | 0.7880958 | 6 | BAX;CASP3;APAF1;CASP9;PINK1;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION | 0.7601810 | 0.9880170 | 0.0642141 | 0.3165225 | 0.7822466 | 12 | SEC13;PREB;SEC31B;SEC24A;SEC24C;SEC23B;SAR1B | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN | 0.7866972 | 0.9880170 | 0.0632191 | 0.3375076 | 0.7808130 | 10 | FCN1;FCN3;COLEC11 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 0.7900943 | 0.9880170 | 0.0643583 | 0.2663337 | 0.7775482 | 26 | NRAS;MAPK1;GNGT2;GNG5;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 0.7600000 | 0.9880170 | 0.0661326 | 0.2797272 | 0.7768745 | 19 | PPP2R2B;PPP2R5D;PPP2R3A;PPP2R3B;PPP2R5A;PPP2R1A;PPP2R2A;AKT2;AKT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY | 0.7292111 | 0.9812475 | 0.0633597 | 0.4039305 | 0.7739150 | 5 | E2F1;RAF1;SRC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7852194 | 0.9880170 | 0.0636424 | 0.2915648 | 0.7712361 | 16 | NRAS;MAPK1;RAF1;MYC;BRAF | non-significant |
| KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 0.7885463 | 0.9880170 | 0.0611693 | 0.3380254 | 0.7651404 | 9 | PAQR8;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7695749 | 0.9880170 | 0.0630790 | 0.2965619 | 0.7639069 | 14 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7941176 | 0.9910460 | 0.0621124 | 0.3077562 | 0.7605818 | 12 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.7682119 | 0.9880170 | 0.0625237 | 0.3476488 | 0.7578745 | 8 | TCF7L1;TCF7;MYC | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 0.7792494 | 0.9880170 | 0.0618406 | 0.3444469 | 0.7508944 | 8 | ELN;C4orf3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION | 0.7660044 | 0.9880170 | 0.0626618 | 0.3767952 | 0.7491460 | 6 | MYCN | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 0.8632287 | 0.9925013 | 0.0577309 | 0.2413912 | 0.7477539 | 33 | CREB3L2;GNGT2;MAP2K6;GNG5;CREB3;ATF4;MAPK13;GNGT1;GNG4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY | 0.7822222 | 0.9880170 | 0.0619763 | 0.3576172 | 0.7477239 | 7 | TCF7L1;TCF7;GSK3B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8151448 | 0.9925013 | 0.0601186 | 0.2840262 | 0.7433898 | 15 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY | 0.7880795 | 0.9880170 | 0.0613026 | 0.3400015 | 0.7412034 | 8 | RAC2;FCGR3B;CRK;FCGR2A;FCGR3A | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_STRAND_BREAK_SIGNALING | 0.8213457 | 0.9925013 | 0.0617054 | 0.3095276 | 0.7391692 | 11 | ATM;RNF8;MDC1;L3MBTL2;RNF168;NBN | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.8267898 | 0.9925013 | 0.0611693 | 0.2777536 | 0.7347033 | 16 | PLCG2;NFATC3;PPP3CC;CALM3;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 0.8876147 | 0.9934889 | 0.0574877 | 0.2397474 | 0.7323878 | 32 | CHRM1;GNGT2;GNG5;PIK3CG;CHRM2;LPAR3;GNGT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_LOADING | 0.8193833 | 0.9925013 | 0.0593488 | 0.3225240 | 0.7300520 | 9 | DDX11;SMC3;STAG1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 0.8215859 | 0.9925013 | 0.0592219 | 0.3215896 | 0.7279371 | 9 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8262806 | 0.9925013 | 0.0594760 | 0.2781010 | 0.7278818 | 15 | NRAS;MAPK1;RAF1;BRAF | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_NEF_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.8076063 | 0.9925013 | 0.0607719 | 0.2825664 | 0.7278561 | 14 | TRADD;NFKB1;MAP3K7;IKBKG;RELA;TRAF2;RIPK1;CHUK;NFKBIA;TAB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381 | 0.8371041 | 0.9925013 | 0.0596037 | 0.2922919 | 0.7223636 | 12 | MFNG;NOTCH1;NOTCH2;RBPJ;MAML2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKR_EIF2ALPHA_SIGNALING_PATHWAY | 0.8355556 | 0.9925013 | 0.0588438 | 0.3338816 | 0.6980963 | 7 | EIF2B1;EIF2B3;EIF2AK2;EIF2B4;EIF2B5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 0.8678414 | 0.9925013 | 0.0566484 | 0.3009721 | 0.6812680 | 9 | CXCR4;ARHGEF1;GNA12;ROCK2;GNA13;RHOA | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY | 0.8644444 | 0.9925013 | 0.0572461 | 0.3237316 | 0.6768741 | 7 | TNF;TRADD;TRAF2;RIPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEME_BIOSYNTHESIS | 0.8722467 | 0.9925013 | 0.0564118 | 0.2954697 | 0.6688131 | 9 | ALAS1;HMBS;CPOX;PPOX | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY | 0.8587196 | 0.9925013 | 0.0572461 | 0.3361638 | 0.6683626 | 6 | APP;MAP2K7;MAPK8 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.9020045 | 0.9934889 | 0.0553643 | 0.2532055 | 0.6627219 | 15 | TRADD;NFKB1;MAP3K7;IKBKG;RELA;TRAF2;RIPK1;CHUK;NFKBIA;TAB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 0.8967890 | 0.9934889 | 0.0570060 | 0.2838073 | 0.6565791 | 10 | APP;VDAC3;PPID | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27 | 0.8955916 | 0.9934889 | 0.0576091 | 0.2740114 | 0.6543545 | 11 | TEX10;RING1;DCAF7 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.8697572 | 0.9925013 | 0.0566484 | 0.3242120 | 0.6445999 | 6 | PRNP;ATF4;EIF2AK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_FKTN_TO_LARGE | 0.9117647 | 1.0000000 | 0.0521630 | 0.4230693 | 0.6440970 | 2 | FKRP;FKTN | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION | 0.9096916 | 1.0000000 | 0.0544556 | 0.2730642 | 0.6180969 | 9 | IDH2;ACLY;IDH3B;IDH1;IDH3A | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.9257541 | 1.0000000 | 0.0560596 | 0.2514405 | 0.6004541 | 11 | PIK3CD;MTOR;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION | 0.9161148 | 1.0000000 | 0.0542316 | 0.3012443 | 0.5989354 | 6 | CDCA5;STAG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE | 0.9357798 | 1.0000000 | 0.0550211 | 0.2536107 | 0.5867201 | 10 | PPP3CC;CALM3;MCOLN1;PPP3R1 | non-significant |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.9468822 | 1.0000000 | 0.0547940 | 0.2196496 | 0.5810088 | 16 | CREB3L2;CREB3;ATF4 | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 0.9694836 | 1.0000000 | 0.0544556 | 0.2109311 | 0.5773604 | 18 | TANK;IKBKE;IRF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 0.9811321 | 1.0000000 | 0.0541201 | 0.1975012 | 0.5765950 | 26 | CBX2;PHC2;SCMH1;RING1;SCML2;ASXL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2 | 0.9445629 | 1.0000000 | 0.0512184 | 0.2890580 | 0.5538237 | 5 | NRBF2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 0.9665924 | 1.0000000 | 0.0521630 | 0.2110980 | 0.5525128 | 15 | APP;VDAC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 0.9722864 | 1.0000000 | 0.0535669 | 0.2046090 | 0.5412239 | 16 | NFKB1;IKBKG;RELA;IFNB1;CHUK;NFKBIA;IFNA10 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 0.9533333 | 1.0000000 | 0.0526973 | 0.2576830 | 0.5387764 | 7 | MTOR;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.9624724 | 1.0000000 | 0.0519512 | 0.2467981 | 0.5380199 | 8 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 0.9772727 | 1.0000000 | 0.0525899 | 0.2123611 | 0.5333031 | 13 | LPAR3;ARHGEF1;GNA12;ARHGEF11;LPAR2;ROCK2;GNA13;LPAR5;RHOA | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 0.9625551 | 1.0000000 | 0.0518458 | 0.2290835 | 0.5185440 | 9 | IKBKE;IRF3;IFNB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 0.9747706 | 1.0000000 | 0.0531298 | 0.2236412 | 0.5173866 | 10 | MET;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_V_D_J_RECOMBINATION | 0.9751131 | 1.0000000 | 0.0524828 | 0.2083262 | 0.5148527 | 12 | PRKDC;DCLRE1C;XRCC6 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS | 0.9757174 | 1.0000000 | 0.0513223 | 0.2503759 | 0.4977987 | 6 | UGP2;GYG1;GYS1;GYG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_POMT_TO_POMK | 0.9786780 | 1.0000000 | 0.0495902 | 0.2538956 | 0.4864540 | 5 | B3GALNT2;POMK;POMGNT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION | 0.9888143 | 1.0000000 | 0.0513223 | 0.1887526 | 0.4862034 | 14 | MAD2L2;MUS81 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2 | 0.9841629 | 1.0000000 | 0.0520570 | 0.1965378 | 0.4857192 | 12 | CSNK2B;RING1;CSNK2A2;DCAF7;CSNK2A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION | 0.9786780 | 1.0000000 | 0.0495902 | 0.2516776 | 0.4822044 | 5 | GALNS;HEXA;HEXB;GLB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_MONOFUNCTIONAL_GLYCOSYLASE | 0.9889625 | 1.0000000 | 0.0507028 | 0.2204801 | 0.4806466 | 8 | UNG;MUTYH;MBD4;APEX1 | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 0.9932886 | 1.0000000 | 0.0511148 | 0.1838532 | 0.4735831 | 14 | NRAS;PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 0.9867841 | 1.0000000 | 0.0507028 | 0.2011948 | 0.4554164 | 9 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_EREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.9931193 | 1.0000000 | 0.0522693 | 0.1834610 | 0.4244311 | 10 | PIK3CD;PIK3CB;AKT2;AKT1;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 0.9976526 | 1.0000000 | 0.0531298 | 0.1528895 | 0.4184891 | 18 | PRNP;VDAC3;CASP3;GRIN2D;SLC25A5;APAF1;SLC25A31;MCU;CASP9;VDAC2;VDAC1;GRIN2A;GRIN2B;GRIN1;CYCS;GRIN2C;SLC25A6;SLC25A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_BIFUNCTIONAL_GLYCOSYLASE | 1.0000000 | 1.0000000 | 0.0501934 | 0.1738982 | 0.3790981 | 8 | PARP1;PARP2;OGG1;APEX1;XRCC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1 | 0.9982332 | 1.0000000 | 0.0400846 | -0.1650122 | -0.3651388 | 10 | ATG14;BECN1;ZFYVE1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 1.0000000 | 1.0000000 | 0.0391956 | -0.1492522 | -0.3831096 | 18 | CAMK2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382 | 0.9946619 | 1.0000000 | 0.0405756 | -0.1747845 | -0.4057591 | 13 | HEY1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 1.0000000 | 1.0000000 | 0.0403295 | -0.1397615 | -0.4109005 | 34 | RPS29;RPS14;RPS23;RPS4Y2;RPS13;RPS9;RPS17;RPS12;RPS15;RPS3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION | 1.0000000 | 1.0000000 | 0.0414880 | -0.1939485 | -0.4114486 | 9 | C7;VTN;C8B;C6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380 | 0.9910714 | 1.0000000 | 0.0409056 | -0.1895708 | -0.4327337 | 12 | HEY1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY | 0.9747748 | 1.0000000 | 0.0420772 | -0.2051493 | -0.4816850 | 14 | IFNA4;TBK1;IFNA5;IFNA16;IFNA21;IFNA6 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION | 0.9857143 | 1.0000000 | 0.0411544 | -0.2127562 | -0.4856590 | 12 | ATG4D;ATG16L1;ATG12 | non-significant |
| KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY | 0.9754816 | 1.0000000 | 0.0407404 | -0.2203404 | -0.4952585 | 11 | IFNA4;TBK1;IFNA5;IFNA16;IFNA21;IFNA6 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_NEIL_GLYCOSYLASE | 0.9817518 | 1.0000000 | 0.0423318 | -0.2344282 | -0.4973234 | 9 | NEIL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUCONEOGENESIS | 0.9718574 | 1.0000000 | 0.0440640 | -0.2740345 | -0.4994284 | 5 | PCK1;PCK2 | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_HOLLIDAY_JUNCTION_RESOLUTION | 0.9662289 | 1.0000000 | 0.0443293 | -0.2772634 | -0.5053130 | 5 | SLX4;EME1;SLX1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 0.9733096 | 1.0000000 | 0.0415718 | -0.2248680 | -0.5220271 | 13 | SLC25A4;SLC25A6;ITPR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RAS_UBIQUITINATION_BY_CUL3_COMPLEX | 0.9581056 | 1.0000000 | 0.0433637 | -0.2724262 | -0.5281717 | 6 | HRAS;CUL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 0.9878893 | 1.0000000 | 0.0395979 | -0.1962526 | -0.5303716 | 23 | COPZ2;TMED10;TMED7;TMED4;TMED3;COPG2;COPB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY | 0.9637681 | 1.0000000 | 0.0428451 | -0.2662761 | -0.5343761 | 7 | RAC3;ITGB3;ITGAV;RAC1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.9861592 | 1.0000000 | 0.0396787 | -0.2028535 | -0.5482103 | 23 | CAMK2B;CREB3L4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9792746 | 1.0000000 | 0.0399219 | -0.2072724 | -0.5547329 | 22 | GNAQ;SLC25A4;SLC25A6;CASP7;ITPR1;PLCB1 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.9607143 | 1.0000000 | 0.0423318 | -0.2434406 | -0.5557024 | 12 | EGF;ERBB2;RPS6KB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.9525547 | 1.0000000 | 0.0437126 | -0.2620157 | -0.5558484 | 9 | TLN2;PXN | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL | 0.9457093 | 1.0000000 | 0.0421619 | -0.2490888 | -0.5598763 | 11 | P2RX2;P2RX4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY | 0.9362477 | 1.0000000 | 0.0444181 | -0.2929752 | -0.5680114 | 6 | MAPK9 | non-significant |
| KEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION | 0.9326047 | 1.0000000 | 0.0445962 | -0.2747611 | -0.5694005 | 8 | IDS;HYAL1;HYAL4;HYAL2;IDUA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 0.9688042 | 1.0000000 | 0.0405756 | -0.2210121 | -0.5754774 | 19 | HTT;SLC25A4;SLC25A6 | non-significant |
| KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY | 0.9513514 | 1.0000000 | 0.0431902 | -0.2483098 | -0.5830245 | 14 | DEPTOR;NPRL2;TELO2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9461806 | 1.0000000 | 0.0417397 | -0.2332677 | -0.5987659 | 18 | GNAQ;ATXN3;SLC25A4;SLC25A6;ITPR1;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_MESP2_SIGNALING | 0.8968105 | 0.9934889 | 0.0477342 | -0.3345401 | -0.6096999 | 5 | LFNG | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION | 0.9199288 | 1.0000000 | 0.0441523 | -0.2669742 | -0.6197758 | 13 | CREB3L4;HTT;CREB1;TAF4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.8925319 | 0.9934889 | 0.0466015 | -0.3262609 | -0.6325447 | 6 | HSPA5;SNCA;EIF2S1;DDIT3 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY | 0.9000000 | 0.9934889 | 0.0453152 | -0.2781161 | -0.6348563 | 12 | TGFB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.9388112 | 1.0000000 | 0.0424170 | -0.2336039 | -0.6401336 | 25 | PIK3R5;GNG11 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.9414802 | 1.0000000 | 0.0415718 | -0.2365013 | -0.6425369 | 24 | PIK3R5;GNG11 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8822496 | 0.9934889 | 0.0454968 | -0.2599277 | -0.6439128 | 16 | SLC25A4;SLC25A6;CASP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY | 0.8967972 | 0.9934889 | 0.0453152 | -0.2778947 | -0.6451275 | 13 | HEY1;DLL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSC1_2_MTORC1_SIGNALING_PATHWAY | 0.8896673 | 0.9934889 | 0.0449543 | -0.2879985 | -0.6473337 | 11 | DEPTOR;TELO2;TSC1;MLST8;TSC2;RPTOR | non-significant |
| KEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX | 0.8998179 | 0.9934889 | 0.0462303 | -0.3124963 | -0.6476009 | 8 | NSMCE1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 0.8915009 | 0.9934889 | 0.0463228 | -0.2700639 | -0.6511082 | 15 | HRAS;EGF;SOS2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.8779599 | 0.9934889 | 0.0473534 | -0.3369069 | -0.6531848 | 6 | MAPK3;MAPK12;MAPK11 | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 0.8717047 | 0.9925013 | 0.0460458 | -0.2675797 | -0.6628690 | 16 | TRAF5;MAPK9;JUN;FOS | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY | 0.8740876 | 0.9927710 | 0.0476387 | -0.3140276 | -0.6661881 | 9 | BMPR2;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 0.8664323 | 0.9925013 | 0.0463228 | -0.2698407 | -0.6684700 | 16 | HRAS;EGF;MAPK3;SOS2;ERBB2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8958333 | 0.9934889 | 0.0442407 | -0.2619110 | -0.6722892 | 18 | BCL2;HRAS;MAPK3;JUN;FOS;CHRNB2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.9013841 | 0.9934889 | 0.0438002 | -0.2517626 | -0.6803869 | 23 | GNAQ;HTT;SLC25A4;SLC25A6;CASP7;ITPR1;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY | 0.8621908 | 0.9925013 | 0.0467883 | -0.3091632 | -0.6841159 | 10 | TRAF5;FADD;CASP7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8625678 | 0.9925013 | 0.0478300 | -0.2846372 | -0.6862436 | 15 | HRAS;FGFR1;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_STRAD_STK11_TSC_SIGNALING_PATHWAY | 0.8561020 | 0.9925013 | 0.0485060 | -0.3326161 | -0.6892960 | 8 | PRKAA2;TSC1;TSC2;STRADB | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS | 0.8511384 | 0.9925013 | 0.0469759 | -0.3070297 | -0.6901099 | 11 | GPX4;GSS;GPX3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING | 0.8542805 | 0.9925013 | 0.0486034 | -0.3564580 | -0.6910900 | 6 | MAPK3;RPS6KA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.8666667 | 0.9925013 | 0.0474483 | -0.2956680 | -0.6942203 | 14 | IGF1R | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_TP53_TO_TRANSCRIPTION | 0.8412409 | 0.9925013 | 0.0493910 | -0.3273418 | -0.6944334 | 9 | GADD45A;POLK;GADD45G;GADD45B | non-significant |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 0.8910035 | 0.9934889 | 0.0443293 | -0.2570398 | -0.6946486 | 23 | GNG11;LPAR1;GNG12;GNB5;LPAR4;GNG13;GNG10 | non-significant |
| KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY | 0.8394161 | 0.9925013 | 0.0494905 | -0.3277495 | -0.6952982 | 9 | THRA;SLC16A2;RXRA;ATP2A2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY | 0.8375912 | 0.9925013 | 0.0495902 | -0.3284294 | -0.6967405 | 9 | TGFB3 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8553345 | 0.9925013 | 0.0482150 | -0.2891828 | -0.6972028 | 15 | HRAS;EGF;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY | 0.8498233 | 0.9925013 | 0.0474483 | -0.3153629 | -0.6978345 | 10 | CCND1;LEF1;APC | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8553345 | 0.9925013 | 0.0482150 | -0.2904277 | -0.7002042 | 15 | HRAS;FGFR1;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION | 0.8451730 | 0.9925013 | 0.0490940 | -0.3614937 | -0.7008530 | 6 | SHARPIN | non-significant |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 0.8990991 | 0.9934889 | 0.0457704 | -0.2536743 | -0.7052019 | 28 | RPA4;POLD4;RPA3;GTF2H5;POLK;XPA | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY | 0.8266200 | 0.9925013 | 0.0483118 | -0.3141261 | -0.7060605 | 11 | HRAS;EGF;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8462929 | 0.9925013 | 0.0487011 | -0.2940815 | -0.7090133 | 15 | HRAS;FGFR1;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 0.8306011 | 0.9925013 | 0.0498907 | -0.3427325 | -0.7102607 | 8 | LRP2;CDON;DHH;PTCH2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.8370884 | 0.9925013 | 0.0472587 | -0.2822878 | -0.7149259 | 17 | CREB3L4;PBX1;NR4A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY | 0.8188406 | 0.9925013 | 0.0502948 | -0.3563407 | -0.7151223 | 7 | MAPK9 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CN_SIGNALING_PATHWAY | 0.8303571 | 0.9925013 | 0.0489954 | -0.3133250 | -0.7152277 | 12 | NFATC4 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM | 0.8268551 | 0.9925013 | 0.0487011 | -0.3241091 | -0.7171881 | 10 | AKR1C1;AKR1C4;AKR1C3;EPHX3;EPHX2;EPHX1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8309609 | 0.9925013 | 0.0487990 | -0.3091140 | -0.7176027 | 13 | SLC25A4;SLC25A6;ITPR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS | 0.8215548 | 0.9925013 | 0.0489954 | -0.3261279 | -0.7216552 | 10 | HSD17B8;HSD3B1;SRD5A3;HSD17B6;AKR1C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 0.8390597 | 0.9925013 | 0.0490940 | -0.2998104 | -0.7228254 | 15 | RPA4;RPA3;RAD50;UIMC1;BRCC3;RBBP8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.8437500 | 0.9925013 | 0.0469759 | -0.2820318 | -0.7239364 | 18 | CREB3L4;PBX1;NR4A1;PRKAR1A;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_SIGNALING | 0.8160714 | 0.9925013 | 0.0497903 | -0.3190954 | -0.7283998 | 12 | RPA4;RAD17;RPA3;ATRIP | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_SPRED_AND_NF1 | 0.8069217 | 0.9925013 | 0.0512184 | -0.3775256 | -0.7319351 | 6 | SPRED2;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 0.8113879 | 0.9925013 | 0.0498907 | -0.3193690 | -0.7414095 | 13 | IGF1R | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_GLC_6P_TO_MAN_P_DOL | 0.7864964 | 0.9880170 | 0.0524828 | -0.3498326 | -0.7421460 | 9 | MPI;DPM2;DPM1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.7832423 | 0.9880170 | 0.0525899 | -0.3859542 | -0.7482762 | 6 | SOD1;HSPA5;EIF2S1;DDIT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY | 0.7892857 | 0.9880170 | 0.0513223 | -0.3280895 | -0.7489307 | 12 | CCND1;AXIN2;LEF1;APC | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.7989324 | 0.9925013 | 0.0506004 | -0.3232102 | -0.7503268 | 13 | SLC25A4;SLC25A6;SNCA | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS | 0.7723292 | 0.9880170 | 0.0514265 | -0.3345389 | -0.7519422 | 11 | GLCE;NDST4;EXTL1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.7807971 | 0.9880170 | 0.0524828 | -0.3751720 | -0.7529139 | 7 | FAF2;CISD2;CISD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 0.8049209 | 0.9925013 | 0.0496901 | -0.3043109 | -0.7538622 | 16 | RTEL1;NHP2;TERF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.7789855 | 0.9880170 | 0.0525899 | -0.3761327 | -0.7548418 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 0.8048359 | 0.9925013 | 0.0488971 | -0.2844146 | -0.7611921 | 22 | CD86;PPP2R2C | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.8036036 | 0.9925013 | 0.0509083 | -0.2789110 | -0.7753586 | 28 | AGTR1;CAMK2B;CREB3L4;GNAQ | non-significant |
| KEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM | 0.7692308 | 0.9880170 | 0.0547940 | -0.4291120 | -0.7820573 | 5 | MAOA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY | 0.7402827 | 0.9875754 | 0.0537873 | -0.3539675 | -0.7832588 | 10 | CCND1;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 0.7539543 | 0.9880170 | 0.0526973 | -0.3171627 | -0.7856998 | 16 | FUT8;ST6GAL2;MAN2A1;MGAT2;MAN2A2;MAN1C1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 0.7441441 | 0.9880170 | 0.0544556 | -0.3379428 | -0.7934804 | 14 | CACNA1D;SLC25A4;CACNA1F;SLC25A6 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 0.7447552 | 0.9880170 | 0.0530213 | -0.2810178 | -0.8013923 | 30 | ITGA11;ITGB5;DOCK1;ITGA3;ITGA2;RAC3;FN1;PXN;ITGB3;BCAR1;ITGA7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPG_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.7264493 | 0.9812475 | 0.0558265 | -0.4017740 | -0.8063000 | 7 | SKP1;UBE2D2;FBXW11;BTRC;RBX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 0.7323689 | 0.9812475 | 0.0553643 | -0.3349112 | -0.8074513 | 15 | DEPTOR;ATG14;TELO2;ULK1;BECN1;MLST8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7500000 | 0.9880170 | 0.0540088 | -0.2930144 | -0.8090362 | 27 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 0.6882662 | 0.9760617 | 0.0567672 | -0.3638600 | -0.8178473 | 11 | ERBB4 | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 0.7508834 | 0.9880170 | 0.0531298 | -0.2772173 | -0.8217547 | 35 | HRAS;FGFR3;FGFR1;MAPK3;FGF18;SOS2;FGF1;FGF3;FGF7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.6943942 | 0.9760617 | 0.0578530 | -0.3413128 | -0.8228853 | 15 | PDGFRB;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.7320144 | 0.9812475 | 0.0551352 | -0.3000559 | -0.8284783 | 27 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 0.6892361 | 0.9760617 | 0.0562941 | -0.3233692 | -0.8300440 | 18 | FZD4;RNF43;FZD10;FZD8 | non-significant |
| KEGG_MEDICUS_VARIANT_EWSR1_WT1_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6830601 | 0.9760617 | 0.0589694 | -0.4315140 | -0.8366061 | 6 | BAIAP3;PDGFA;TSPAN7 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM | 0.7073171 | 0.9772975 | 0.0587186 | -0.4603924 | -0.8390659 | 5 | GRIN2C;GRIN1;GRIN2B;GRIN2A | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 0.7117117 | 0.9786298 | 0.0565300 | -0.3019756 | -0.8394770 | 28 | PIK3R5;GNG11;PREX1;MAPK9;GNG12 | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_DEGRADATION_BY_EXTRACELLULAR_ENDOLYSOSOMAL_DNASE | 0.6847826 | 0.9760617 | 0.0585938 | -0.4194647 | -0.8418026 | 7 | DNASE1L2;DNASE1;DNASE1L1;DNASE2B | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 0.6998255 | 0.9760617 | 0.0558265 | -0.2940185 | -0.8453048 | 31 | FGFR3;FGFR1;FGF18;FGF1;FGF3;FGF7;RPS6KB1;FGF20;FGF19;FGF10;FGF4;FGF5;FGF22;FGF23;AKT3;FGF6;FGF8;FGF2;FGFR4 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 0.6618445 | 0.9760617 | 0.0601186 | -0.3536758 | -0.8526917 | 15 | KITLG;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRAPPI_RAB1_SIGNALING_PATHWAY | 0.6532847 | 0.9760617 | 0.0611693 | -0.4030085 | -0.8549549 | 9 | TRAPPC6A;TRAPPC4;TRAPPC2;RAB1B;TRAPPC6B;TRAPPC5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 0.6431095 | 0.9760617 | 0.0603786 | -0.3879320 | -0.8584152 | 10 | CD86 | non-significant |
| KEGG_MEDICUS_REFERENCE_INTRINSIC_APOPTOTIC_PATHWAY | 0.6494662 | 0.9760617 | 0.0602484 | -0.3702225 | -0.8594649 | 13 | BCL2;PMAIP1;CASP7;BCL2L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 0.6828829 | 0.9760617 | 0.0584693 | -0.3091810 | -0.8595077 | 28 | MNAT1;CCNH;POLR2E;ERCC8;CDK7;GTF2H5;POLR2L;UVSSA;POLR2A;POLR2J2 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.6539162 | 0.9760617 | 0.0610364 | -0.4449650 | -0.8626845 | 6 | CACNA1D;CACNA1F;CACNA1B;CACNA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION | 0.6199650 | 0.9760617 | 0.0617054 | -0.3849878 | -0.8653362 | 11 | RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 0.7188552 | 0.9801132 | 0.0529130 | -0.2428201 | -0.8675404 | 81 | RPS29;RPS14;RPL17;RPS23;RPL29;RPL23;RPLP1;RPL9;RPL31;RPL41;RPL22;RPS4Y2;RPL23A;RPL24;RPL13A;RPS13;RPS9;RPL38;RPL10;RPL21;RPL37A;RPS17;RPL14;RPL8;RPS12 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 0.6387900 | 0.9760617 | 0.0610364 | -0.3737095 | -0.8675600 | 13 | DHCR24;TM7SF2;SC5D;SQLE;NSDHL;FDFT1;HSD17B7;MSMO1;CYP51A1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P53_MEDIATED_TRANSCRIPTION | 0.6307420 | 0.9760617 | 0.0613026 | -0.3928272 | -0.8692472 | 10 | MDM2;GADD45A;POLK;GADD45G;GADD45B | non-significant |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 0.6031196 | 0.9732704 | 0.0625237 | -0.3442021 | -0.8717311 | 17 | GHR;EPO;PRLR;PRL;LEP;EPOR;CSF3R;LEPR | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.5996534 | 0.9732704 | 0.0628004 | -0.3467103 | -0.8780833 | 17 | PDGFRB;CAMK2B;PDGFA | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR2_TO_CELL_SURFACE_MOLECULE_ENDOCYTOSIS | 0.6338798 | 0.9760617 | 0.0625237 | -0.4540360 | -0.8802712 | 6 | CD86 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION | 0.6268116 | 0.9760617 | 0.0628004 | -0.4386593 | -0.8803233 | 7 | BDNF;HTT | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 0.6436170 | 0.9760617 | 0.0605093 | -0.3133353 | -0.8821421 | 29 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN | 0.6510319 | 0.9760617 | 0.0626618 | -0.4848299 | -0.8836033 | 5 | CD46;CFH;CR1;CD55 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY | 0.6338798 | 0.9760617 | 0.0625237 | -0.4560289 | -0.8841349 | 6 | PLCD4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 0.6211293 | 0.9760617 | 0.0635008 | -0.4607796 | -0.8933455 | 6 | MAGI2;MAGI1;PTEN;AKT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6003617 | 0.9732704 | 0.0647943 | -0.3708814 | -0.8941733 | 15 | CCND1;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION | 0.6174863 | 0.9760617 | 0.0637845 | -0.4318530 | -0.8949495 | 8 | AGL;PYGL | non-significant |
| KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.6014493 | 0.9732704 | 0.0647943 | -0.4470281 | -0.8971182 | 7 | BCL2;CASP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 0.6144144 | 0.9760617 | 0.0635008 | -0.3227923 | -0.8973464 | 28 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 0.6024735 | 0.9732704 | 0.0635008 | -0.3027202 | -0.8973532 | 35 | ADCY1;ADCY9;SMARCD3;SMARCA4;ADCY6;ADCY5;DPF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4 | 0.6036036 | 0.9732704 | 0.0643583 | -0.3834393 | -0.9003050 | 14 | FZD4;LRP4;FZD10;FZD8 | non-significant |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 0.6003460 | 0.9732704 | 0.0626618 | -0.3350571 | -0.9054899 | 23 | ESR1;CREB3L4;HRAS;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 0.5979021 | 0.9732704 | 0.0633597 | -0.3185603 | -0.9084541 | 30 | DYNLRB2;DYNC2LI1;DYNLT3;DCTN4;ACTR10;DYNC2H1 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 0.5761821 | 0.9732704 | 0.0652353 | -0.4051888 | -0.9107419 | 11 | KITLG | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA1_TO_P53_MEDIATED_TRANSCRIPTION | 0.5777385 | 0.9732704 | 0.0655321 | -0.4120541 | -0.9117925 | 10 | USP7;GADD45A;POLK;GADD45G;GADD45B | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5711775 | 0.9732704 | 0.0658312 | -0.3690375 | -0.9142079 | 16 | ESR1;HRAS;MAPK3;JUN;FOS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.5817556 | 0.9732704 | 0.0639272 | -0.3375543 | -0.9170824 | 24 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.5847751 | 0.9732704 | 0.0639272 | -0.3313631 | -0.9190773 | 26 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5;PRKAR1A;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY | 0.5894161 | 0.9732704 | 0.0661326 | -0.4343625 | -0.9214705 | 9 | BMPR1B;SMAD1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM | 0.6029144 | 0.9732704 | 0.0649408 | -0.4753131 | -0.9215225 | 6 | GRIN2C;PDYN;GRIN1;GRIN2B;GRIN2A | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5660714 | 0.9732704 | 0.0670513 | -0.4044496 | -0.9232381 | 12 | CCND1;HRAS;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION | 0.5760870 | 0.9732704 | 0.0668966 | -0.4614900 | -0.9261411 | 7 | C5;C7 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.5674740 | 0.9732704 | 0.0653834 | -0.3344077 | -0.9275216 | 26 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.5611888 | 0.9732704 | 0.0664364 | -0.3417555 | -0.9364965 | 25 | CACNA1H;CAMK2B;CREB3L4;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 0.5444840 | 0.9672239 | 0.0687943 | -0.4034459 | -0.9365925 | 13 | PDGFRB;PDGFA | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 0.5351351 | 0.9672239 | 0.0702813 | -0.4007794 | -0.9410188 | 14 | RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 0.5387387 | 0.9672239 | 0.0699459 | -0.3390793 | -0.9426234 | 28 | ELMO3;ITGA11;ITGB5;DOCK1;ITGA3;ITGA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 0.5184534 | 0.9547389 | 0.0706196 | -0.3816393 | -0.9454261 | 16 | FZD4;WNT5A;FZD10;FZD8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5244123 | 0.9547389 | 0.0714786 | -0.3925093 | -0.9463170 | 15 | CCND1;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION | 0.5464481 | 0.9672239 | 0.0697793 | -0.4601065 | -0.9535005 | 8 | DLL1;DLL4;JAG1;NEURL1B;MIB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.5446266 | 0.9672239 | 0.0699459 | -0.4613258 | -0.9560274 | 8 | BCL2;SOD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY | 0.5602190 | 0.9732704 | 0.0686326 | -0.4507142 | -0.9561593 | 9 | GNAQ;LPAR1;LPAR4;ARHGEF12 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.5035587 | 0.9547389 | 0.0727141 | -0.4166514 | -0.9672488 | 13 | IL20;IL20RA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.5157343 | 0.9547389 | 0.0706196 | -0.3533106 | -0.9681604 | 25 | CACNA1H;CAMK2B;CREB3L4;CACNA1D | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 0.4821124 | 0.9504064 | 0.0727141 | -0.3087516 | -0.9694325 | 44 | DNALI1;DNAH7;DNAH5;TUBA3D;DCTN4;ACTR10;DNAI1;DNAL1;HTT | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.5078809 | 0.9547389 | 0.0714786 | -0.3724631 | -0.9735954 | 20 | PDE8B;CREB3L4;PBX1;NR4A1;PRKAR1A;CREB1;PDE11A | non-significant |
| KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME | 0.5036232 | 0.9547389 | 0.0736213 | -0.4874190 | -0.9781766 | 7 | PRKAR2B;PRKAR1A;PRKACG;PRKAR1B;PRKAR2A | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG7_TO_ALG11 | 0.5227687 | 0.9547389 | 0.0720033 | -0.5047561 | -0.9786058 | 6 | ALG11;ALG2;ALG1;ALG13;ALG14 | non-significant |
| KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 0.5196998 | 0.9547389 | 0.0738053 | -0.5375532 | -0.9796916 | 5 | CYP17A1;CYP21A2;HSD11B2;CYP11B2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_RXRA_LXRA_MEDIATED_TRANSCRIPTION | 0.5191257 | 0.9547389 | 0.0723571 | -0.5063630 | -0.9817212 | 6 | CCND1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 0.4786477 | 0.9465908 | 0.0753094 | -0.4246988 | -0.9859306 | 13 | GLI3;GLI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.4766031 | 0.9460010 | 0.0741759 | -0.3905857 | -0.9892027 | 17 | PDGFRB;PDGFA;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 0.4604569 | 0.9261970 | 0.0766747 | -0.4016344 | -0.9949595 | 16 | HEY1;HEYL;DLL1;HES5;ERBB2;DLL4;HES1;HEY2;JAG1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BPA_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4608541 | 0.9261970 | 0.0772747 | -0.4294639 | -0.9969929 | 13 | ESR1;HRAS;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY | 0.4711033 | 0.9406870 | 0.0753094 | -0.4436504 | -0.9971921 | 11 | BMPR2;ACVR2B;HAMP;SMAD1 | non-significant |
| KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4711033 | 0.9406870 | 0.0753094 | -0.4437731 | -0.9974678 | 11 | RET;HRAS;MAPK3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.4561102 | 0.9256793 | 0.0760837 | -0.3680213 | -0.9998562 | 24 | CACNA1H;CAMK2B;CREB3L4;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 0.4517241 | 0.9228292 | 0.0766747 | -0.3265781 | -1.0050290 | 42 | DNALI1;DNAH7;DNAH5;TUBA3D;DCTN4;ACTR10;DNAI1;DNAL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BILE_ACID_BIOSYNTHESIS | 0.4594595 | 0.9261970 | 0.0780892 | -0.4290929 | -1.0074983 | 14 | ACOX2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.4325260 | 0.9088860 | 0.0791317 | -0.3754344 | -1.0146092 | 23 | ADCY1;ADCY9;CREB3L4;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION | 0.4553734 | 0.9256793 | 0.0791317 | -0.5251636 | -1.0181711 | 6 | ATXN1;ITPR1;RORA;GRM1;SLC1A6 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4134276 | 0.8855075 | 0.0826646 | -0.3526161 | -1.0212708 | 32 | ADCY1;ADCY9;CREB3L4;PBX1;NR4A1;ADCY6;ADCY5;MRAP;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY | 0.4363958 | 0.9088860 | 0.0797706 | -0.4640587 | -1.0268684 | 10 | MAPK9;MAP3K12 | non-significant |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.4280763 | 0.9074630 | 0.0797706 | -0.4067500 | -1.0301408 | 17 | ADCY1;ADCY9;CX3CR1;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.4434307 | 0.9088860 | 0.0806388 | -0.4881493 | -1.0355753 | 9 | UQCRQ;UQCRB;UQCR11;CYC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY | 0.4343257 | 0.9088860 | 0.0795565 | -0.4613170 | -1.0369012 | 11 | RALGDS;HRAS;EGF;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3829787 | 0.8594720 | 0.0870516 | -0.3722375 | -1.0479712 | 29 | GLI3;WNT2B;BMP4;GLI1;WNT5A;WNT3A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3829787 | 0.8594720 | 0.0870516 | -0.3722375 | -1.0479712 | 29 | GLI3;WNT2B;BMP4;GLI1;WNT5A;WNT3A | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 0.3919156 | 0.8594720 | 0.0852885 | -0.4253740 | -1.0537689 | 16 | IGF1R;IGF2;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY | 0.4045936 | 0.8730330 | 0.0838361 | -0.4766106 | -1.0546432 | 10 | ADCY9;ADCY6;AQP2;AVPR2 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION | 0.4221014 | 0.9009683 | 0.0828962 | -0.5299676 | -1.0635653 | 7 | IVD;MCCC2;HMGCL;AUH | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.4061931 | 0.8730330 | 0.0852885 | -0.5504612 | -1.0672174 | 6 | MAPK9;HTT | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.4061931 | 0.8730330 | 0.0852885 | -0.5509835 | -1.0682300 | 6 | ATG14;ATXN3;BECN1;AMBRA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.3796134 | 0.8594720 | 0.0870516 | -0.4315819 | -1.0691477 | 16 | CCND1;HRAS;EGF;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.4007286 | 0.8730330 | 0.0860347 | -0.5527019 | -1.0715615 | 6 | ATG14;HTT;BECN1;AMBRA1 | non-significant |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.3652803 | 0.8432343 | 0.0908241 | -0.4469314 | -1.0775254 | 15 | IGF1R;IGF2;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.3510638 | 0.8358020 | 0.0919686 | -0.3848016 | -1.0833432 | 29 | ADCY1;ADCY9;CREB3L4;PBX1;NR4A1;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 0.3607143 | 0.8394066 | 0.0908241 | -0.4747728 | -1.0837649 | 12 | ESR1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ANXA2_S100A10_REGULATED_ACTIN_CYTOSKELETON | 0.3902439 | 0.8594720 | 0.0891647 | -0.5965371 | -1.0871898 | 5 | AHNAK;ANXA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_VALINE_DEGRADATION | 0.3770492 | 0.8594720 | 0.0894367 | -0.5291093 | -1.0964983 | 8 | ALDH6A1;ECHS1;HIBADH;ACADM | non-significant |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 0.3184165 | 0.8236170 | 0.0959207 | -0.4072892 | -1.1065410 | 24 | PIGV;PIGH;PIGT;PIGX;PIGQ;PIGP;PIGS;PIGB;PIGF;PIGG;DPM2;PGAP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST | 0.3434164 | 0.8261482 | 0.0934449 | -0.4767868 | -1.1068521 | 13 | BMP4;CHRD;GREM1;GREM2;GDF6 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY | 0.3661202 | 0.8432343 | 0.0911073 | -0.5342586 | -1.1071694 | 8 | MAPK9;JUN;FOS | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 0.3362218 | 0.8261482 | 0.0931455 | -0.4270804 | -1.1120437 | 19 | BMP4;BMPR1B;BMPR2;GDF6;ACVR2B;BMP8B;SMAD1;BMP8A | non-significant |
| KEGG_MEDICUS_REFERENCE_C9ORF72_MEDIATED_AUTOPHAGY_INITIATION | 0.3586957 | 0.8386418 | 0.0919686 | -0.5562430 | -1.1162960 | 7 | SMCR8;WDR41;ULK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.3303887 | 0.8261482 | 0.0952880 | -0.5056437 | -1.1188874 | 10 | SQSTM1;FAF2;CISD2;CISD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.3128391 | 0.8205397 | 0.0999277 | -0.4645203 | -1.1199313 | 15 | AREG;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.2827225 | 0.7872319 | 0.1039585 | -0.3921093 | -1.1273161 | 31 | ADCY1;ADCY9;CREB3L4;PBX1;NR4A1;ADCY6;ADCY5;MRAP;CREB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR | 0.3406193 | 0.8261482 | 0.0952880 | -0.5818918 | -1.1281541 | 6 | CFHR3;CFHR2;CFHR4;CFH;CFHR5 | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 0.3333333 | 0.8261482 | 0.0965630 | -0.5499055 | -1.1395952 | 8 | PGR | non-significant |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 0.3171577 | 0.8236170 | 0.0965630 | -0.4502092 | -1.1402061 | 17 | MNAT1;CETN2;CCNH;CDK7;GTF2H5 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE | 0.3227017 | 0.8254229 | 0.1002791 | -0.6256876 | -1.1403168 | 5 | XYLT2;XYLT1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.2834783 | 0.7872319 | 0.1035763 | -0.3782005 | -1.1448013 | 39 | NDUFC2;NDUFA2;NDUFB10;NDUFB4;NDUFB1;NDUFA7;NDUFA6;NDUFS8;NDUFS4;NDUFC1;NDUFA1;NDUFA5 | non-significant |
| KEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION | 0.3074205 | 0.8097587 | 0.0995791 | -0.5194874 | -1.1495208 | 10 | ACADSB;ACAA2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY | 0.3242259 | 0.8259087 | 0.0982123 | -0.5552263 | -1.1506217 | 8 | NQO1;AKR1C1;AKR1C4;AKR1C3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.2690972 | 0.7783700 | 0.1067299 | -0.3867883 | -1.1666751 | 38 | NDUFC2;NDUFA2;NDUFB10;NDUFB4;NDUFB1;NDUFA7;NDUFA6;NDUFS8;NDUFS4;NDUFC1;NDUFA1;NDUFA5 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN | 0.2969035 | 0.7887693 | 0.1035763 | -0.6019969 | -1.1671333 | 6 | ATG14;UVRAG;BECN1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.2626087 | 0.7733698 | 0.1083943 | -0.3859867 | -1.1683701 | 39 | NDUFC2;NDUFA2;NDUFB10;NDUFB4;NDUFB1;NDUFA7;NDUFA6;NDUFS8;NDUFS4;NDUFC1;NDUFA1;NDUFA5 | non-significant |
| KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.2785714 | 0.7872319 | 0.1063233 | -0.5124059 | -1.1696701 | 12 | KIF5C | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION | 0.2934783 | 0.7872319 | 0.1039585 | -0.5841858 | -1.1723730 | 7 | GUSB;IDS;GNS | non-significant |
| KEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.2937956 | 0.7872319 | 0.1043440 | -0.5527414 | -1.1726032 | 9 | CALCOCO2;SQSTM1;TBK1;NBR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.2950530 | 0.7872319 | 0.1020801 | -0.5303676 | -1.1735965 | 10 | UQCRQ;UQCRB;UQCR11;HTT;CYC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 0.2332155 | 0.7254293 | 0.1172497 | -0.3643591 | -1.1739505 | 50 | AGTR1;GRPR;PTGER3;BDKRB2;HTR2B;GNA14;BDKRB1;F2R;EDNRA;GNAQ;OXTR | non-significant |
| KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.2666667 | 0.7783700 | 0.1096841 | -0.5018870 | -1.1784167 | 14 | CALCOCO2;SQSTM1;FAF2;NBR1;CISD2;CISD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION | 0.2859745 | 0.7872319 | 0.1059203 | -0.5725806 | -1.1865860 | 8 | RABEP1;RABGEF1;EEA1;RAB5C;RAB5B | non-significant |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 0.2422145 | 0.7385753 | 0.1133129 | -0.4410330 | -1.1918890 | 23 | CACNA1H;CACNA1D;SLC25A4;CACNA1F;SLC25A6;CASP7;CACNA1G | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 0.2636204 | 0.7733698 | 0.1088201 | -0.4824572 | -1.1951797 | 16 | PGR;CCND1;HRAS;MAPK3;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 0.2609457 | 0.7733698 | 0.1092500 | -0.5343962 | -1.2011611 | 11 | IGF1R;IGF2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.2139130 | 0.7032460 | 0.1221079 | -0.3977670 | -1.2040287 | 39 | NDUFC2;NDUFA2;NDUFB10;NDUFB4;NDUFB1;NDUFA7;NDUFA6;NDUFS8;NDUFS4;NDUFC1;SNCA;NDUFA1;NDUFA5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 0.2604736 | 0.7733698 | 0.1119183 | -0.5817500 | -1.2055881 | 8 | RET | non-significant |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 0.1807018 | 0.6259696 | 0.1350020 | -0.3700185 | -1.2223269 | 56 | NDUFC2;NDUFA2;NDUFB10;UQCRQ;NDUFAF1;UQCRB;NDUFAF6;COX16;COX5A;NDUFA6;COX14;CYC1;COX11;NDUFS8;COA3;NDUFS4;COX8A;NDUFAF3;NDUFAF2;NDUFA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR | 0.2295374 | 0.7254293 | 0.1188150 | -0.5315721 | -1.2340352 | 13 | WDFY3;CALCOCO2;SQSTM1;NBR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.1737649 | 0.6155121 | 0.1357409 | -0.3941004 | -1.2374143 | 44 | MAPT;NDUFC2;NDUFA2;NDUFB10;NDUFB4;NDUFB1;NDUFA7;NDUFA6;NDUFS8;NDUFS4;NDUFC1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.2214411 | 0.7111106 | 0.1204334 | -0.5014132 | -1.2421390 | 16 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2214411 | 0.7111106 | 0.1204334 | -0.5014451 | -1.2422180 | 16 | COX6C;COX7A1;COX7C;COX5A;COX6A1;COX4I2 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.2081851 | 0.6928309 | 0.1256399 | -0.5422459 | -1.2588142 | 13 | HPGD;FUT8;SIX4;MEIS1;EYA1;SIX1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.1913696 | 0.6473103 | 0.1357409 | -0.6994542 | -1.2747565 | 5 | MAPK9;JUN;FOS | non-significant |
| KEGG_MEDICUS_REFERENCE_CREATINE_PATHWAY | 0.1839709 | 0.6291600 | 0.1364904 | -0.6584896 | -1.2766596 | 6 | GAMT;GATM | non-significant |
| KEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.1770073 | 0.6190255 | 0.1395997 | -0.6081679 | -1.2901867 | 9 | VPS18 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR | 0.1675676 | 0.6030484 | 0.1429011 | -0.5526473 | -1.2976004 | 14 | VPS18;BIRC6;TECPR2;VPS41 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR | 0.1657559 | 0.6030484 | 0.1446305 | -0.6694562 | -1.2979214 | 6 | BMPR2;ACVR2B | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY | 0.1672598 | 0.6030484 | 0.1420566 | -0.5613900 | -1.3032569 | 13 | MAPK9;HRAS;EGF;MAP3K1;SOS2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY | 0.1757246 | 0.6180315 | 0.1395997 | -0.6495160 | -1.3034809 | 7 | BMPR1B;BMPR2;SMAD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.1523643 | 0.5715969 | 0.1482615 | -0.5899608 | -1.3260535 | 11 | AREG | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS | 0.1177536 | 0.5097167 | 0.1737478 | -0.7717608 | -1.3289909 | 4 | SULT1A2;SULT1A1;CYP1A2;SULT1A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY | 0.1220401 | 0.5101398 | 0.1709323 | -0.6513699 | -1.3498647 | 8 | TGFBR1;ACVR2B;ACVR1B;SMAD1;MSTN;SMAD9 | non-significant |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 0.1320072 | 0.5306005 | 0.1631801 | -0.5630075 | -1.3573781 | 15 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.1074681 | 0.4808660 | 0.1830239 | -0.6577679 | -1.3631235 | 8 | VPS18 | non-significant |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 0.1103327 | 0.4878284 | 0.1766943 | -0.5179239 | -1.3666050 | 21 | CACNA2D2;CACNG6;CACNG1;CACNG4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.1219081 | 0.5101398 | 0.1682382 | -0.6181280 | -1.3677926 | 10 | MYL5;MYL7;MYL9;MYL2;MYL10 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1247740 | 0.5102495 | 0.1682382 | -0.5706777 | -1.3758705 | 15 | COX6C;COX7A1;COX7C;COX5A;COX6A1;COX4I2;COX8A | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY | 0.0875912 | 0.4303094 | 0.2042948 | -0.6539076 | -1.3872204 | 9 | MYL5;MYL7;MYL9;MYL2;MYL10 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0851449 | 0.4250380 | 0.2065879 | -0.6925451 | -1.3898339 | 7 | ESR1;EGF;DLL1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_CAMP_SIGNALING_PATHWAY | 0.1117117 | 0.4904223 | 0.1782199 | -0.5920588 | -1.3901376 | 14 | ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_VARIANT_AREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.1024735 | 0.4695639 | 0.1847065 | -0.6308793 | -1.3960086 | 10 | AREG | non-significant |
| KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY | 0.0837887 | 0.4250380 | 0.2089550 | -0.6761078 | -1.4011301 | 8 | ACVR2B;SMAD3;SMAD2;ACVR1B;NODAL | non-significant |
| KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA | 0.0837887 | 0.4250380 | 0.2089550 | -0.6783604 | -1.4057983 | 8 | FBN1;TGFB3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1005199 | 0.4643421 | 0.1847065 | -0.5595054 | -1.4170111 | 17 | COX6C;COX7A1;COX7C;COX5A;COX6A1;COX4I2;COX8A | non-significant |
| KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY | 0.0710383 | 0.3887036 | 0.2279872 | -0.6891892 | -1.4282394 | 8 | TGFB3;TGFBR1;SMAD3;SMAD2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION | 0.0619137 | 0.3615526 | 0.2489111 | -0.7880964 | -1.4363070 | 5 | HGD;FAH;HPD | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.0602190 | 0.3572938 | 0.2489111 | -0.6796629 | -1.4418585 | 9 | KIF5C | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION | 0.0840630 | 0.4250380 | 0.2042948 | -0.6417366 | -1.4424300 | 11 | ACADSB;ACADL;ACAA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 0.0595447 | 0.3572938 | 0.2450418 | -0.5466766 | -1.4424725 | 21 | CACNA2D2;CACNG6;CACNG1;CACNG4;CASQ2;CACNB2;ASPH;CACNB4;CACNG3;CACNA2D4;CACNA1C;TRDN;CACNG7 | non-significant |
| KEGG_MEDICUS_REFERENCE_RENIN_ANGIOTENSIN_SIGNALING_PATHWAY | 0.0506567 | 0.3371664 | 0.2765006 | -0.7963963 | -1.4514336 | 5 | AGTR1;AGT | non-significant |
| KEGG_MEDICUS_REFERENCE_HYDROLYSIS_OF_SPHINGOMYELIN | 0.0579710 | 0.3572938 | 0.2529611 | -0.7266394 | -1.4582561 | 7 | ASAH1;SMPD3;SMPD2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY | 0.0293027 | 0.2458722 | 0.3524879 | -0.7307353 | -1.5143373 | 8 | INHBA;ACVR2B;SMAD3;SMAD2;ACVR1B | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 0.0506329 | 0.3371664 | 0.2712886 | -0.6281947 | -1.5145406 | 15 | ADCY1;ADCY9;PLN;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 0.0153815 | 0.1670379 | 0.3807304 | -0.4603405 | -1.5180683 | 54 | RET;ERBB4;PDGFRB;PDGFD;PDGFC;PDGFA;ERBB3;MST1R;FGFR3;HGF;EGF;FGFR1;VEGFC;FGF18;MST1;FGF1;FGF3;FGF7;ERBB2;VEGFB | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 0.0205318 | 0.1955259 | 0.3524879 | -0.5590444 | -1.5319230 | 25 | CACNA2D2;CACNA1H;CACNG6;CACNG1;CACNG4;CACNA1D | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 0.0063821 | 0.1039612 | 0.4070179 | -0.4233752 | -1.5352386 | 88 | AREG;KITLG;IGF1R;ERBB4;PDGFRB;IGF2;PDGFD;INSR;PDGFC;PDGFA;ERBB3;TEK;PIK3R1;HRAS;FGFR3;HGF;BDNF;EGF;FGFR1;VEGFC;FGF18 | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 0.0098371 | 0.1259970 | 0.3807304 | -0.4266119 | -1.5517417 | 91 | AREG;RET;KITLG;IGF1R;ERBB4;PDGFRB;IGF2;PDGFD;INSR;PDGFC;PDGFA;ERBB3;TEK;HRAS;FGFR3;HGF;BDNF;EGF;FGFR1;MAPK3;ARTN;VEGFC;FGF18 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_PAI | 0.0358751 | 0.2708131 | 0.3217759 | -0.8017397 | -1.5543885 | 6 | PLAT;SERPINA5 | non-significant |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 0.0303865 | 0.2461430 | 0.3524879 | -0.6321956 | -1.5661233 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 0.0063072 | 0.1039612 | 0.4070179 | -0.4374738 | -1.5673584 | 82 | AREG;KITLG;IGF1R;ERBB4;PDGFRB;IGF2;PDGFD;INSR;PDGFC;PDGFA;ERBB3;TEK;PIK3R1;FGFR3;HGF;BDNF;EGF;FGFR1;VEGFC;FGF18 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0099739 | 0.1259970 | 0.3807304 | -0.5725315 | -1.5808049 | 27 | DNALI1;DNAH7;DNAH5;DCTN4;ACTR10;DNAI1;DNAL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 0.0235322 | 0.2080923 | 0.3524879 | -0.6456455 | -1.5994424 | 16 | CGA;ADCY1;ADCY9;ADCY6;ADCY5 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 0.0095648 | 0.1259970 | 0.3807304 | -0.5878981 | -1.6109894 | 25 | IGF1R;ERBB4;PDGFRB;INSR;ERBB3;TEK;FGFR3;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 0.0031633 | 0.0753105 | 0.4317077 | -0.8958220 | -1.6326370 | 5 | SCUBE2;HHAT;DISP1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.0027010 | 0.0668773 | 0.4317077 | -0.6165121 | -1.7022389 | 27 | DNALI1;DNAH7;DNAH5;SOD1;DCTN4;ACTR10;DNAI1;DNAL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0000031 | 0.0004805 | 0.6272567 | -0.9029928 | -2.0296548 | 11 | TFF1;ESR1;PGR;BCL2;KRT19 | significant |
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| pathway | pval | padj | log2err | ES | NES | size | leadingEdge | adjPvalue |
|---|---|---|---|---|---|---|---|---|
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.0001248 | 0.0772313 | 0.5188481 | 0.8088672 | 2.0319843 | 13 | MMP1;ACE2;MMP3;IL12A;CCL2;CYBB;IL6;IL1B | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M | 0.0009670 | 0.0777494 | 0.4772708 | 0.8137620 | 1.8949339 | 10 | CDK1;CCNB2;CCNB3;CCNB1;CHEK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M | 0.0004487 | 0.0777494 | 0.4984931 | 0.8369124 | 1.8857954 | 9 | CDK1;CCNB2;CCNB3;CCNB1;CHEK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY | 0.0017724 | 0.0777494 | 0.4550599 | 0.7500257 | 1.8841664 | 13 | CCL3;CCL4;CCL2;CCL5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0010505 | 0.0777494 | 0.4550599 | 0.7202251 | 1.8638882 | 15 | TNFSF10;CASP7;FASLG;BID;CASP8;CASP3;CASP10 | non-significant |
| KEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS | 0.0019869 | 0.0777494 | 0.4317077 | 0.7598298 | 1.8622520 | 12 | KMO;KYNU;TDO2;IDO1;QPRT | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00536 | 0.0006872 | 0.0777494 | 0.4772708 | 0.7835811 | 1.8599025 | 11 | CCNE1;E2F1;CCNE2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00264 | 0.0008287 | 0.0777494 | 0.4772708 | 0.7799189 | 1.8512101 | 11 | CCNE1;E2F1;CCNE2;SKP2;CCNA2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0024579 | 0.0777494 | 0.4317077 | 0.7541528 | 1.8483384 | 12 | HLA-E;HLA-C;HLA-B;CALR;TAP1;HLA-G;B2M;HLA-F;HLA-A;PDIA3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M | 0.0022106 | 0.0777494 | 0.4317077 | 0.7907350 | 1.8413131 | 10 | CDK1;CCNB2;CCNB3;CHEK2;CCNB1;CHEK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M | 0.0003597 | 0.0777494 | 0.4984931 | 0.8808840 | 1.8385470 | 7 | CDK1;CCNB2;CCNB3;CCNB1;CHEK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00497 | 0.0012597 | 0.0777494 | 0.4550599 | 0.8085437 | 1.8218729 | 9 | CCNE1;E2F1;CCNE2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE | 0.0041709 | 0.0956218 | 0.4070179 | 0.7367972 | 1.8058018 | 12 | TTK;SKA3;NDC80;NUF2;AURKB;SKA2;SPC25;SKA1;SPC24 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P27_CELL_CYCLE_G1_S | 0.0021114 | 0.0777494 | 0.4317077 | 0.6965906 | 1.8027239 | 15 | CCNE1;E2F1;CCNE2;CKS1B;SKP2;RBX1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P27_CELL_CYCLE_G1_S_N00482 | 0.0018427 | 0.0777494 | 0.4550599 | 0.7981953 | 1.7985551 | 9 | CCNE1;E2F1;CCNE2;CCNA2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_P27_CELL_CYCLE_G1_S | 0.0024794 | 0.0777494 | 0.4317077 | 0.6953757 | 1.7857072 | 14 | CCNE1;E2F1;CCNE2;SKP2;RBX1;CCNA2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX | 0.0026259 | 0.0777494 | 0.4317077 | 0.7455273 | 1.7695782 | 11 | SPAG5;AURKA;NDC80;NUF2;CENPE;AURKB;SPC25;SPC24 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.0019207 | 0.0777494 | 0.4550599 | 0.8399880 | 1.7531904 | 7 | ERBB2;STAT1;VEGFA;EGF | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_P21_CELL_CYCLE_G1_S_N00498 | 0.0028143 | 0.0777494 | 0.4317077 | 0.8086184 | 1.7432957 | 8 | CCNE1;E2F1;CCNE2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_RECRUITMENT_AND_FORMATION_OF_THE_MCC | 0.0035229 | 0.0908609 | 0.4317077 | 0.7724751 | 1.7406004 | 9 | CDC20;BUB1;TTK;NDC80;AURKB;BUB1B;MAD2L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION | 0.0013919 | 0.0777494 | 0.4550599 | 0.4595694 | 1.7339640 | 81 | RPL23A;RPL23;RPL18A;RPS5;RPS8;RPSA;RPL36A;RPL7A;RPL38;RPLP2;RPL30;RPS12;RPS19;RPS13;RPLP1;RPL36;RPL19;RPL10A;RPL31;RPL24;RPS6;RPS20;RPS10;RPS4Y2;RPL37A;RPS17;RPS27;RPL9;RPL12;RPS16;RPL35A;RPL35;RPS4X;RPL3;RPL41;RPS3;RPL39;RPL21;RPS28;RPS7;RPL10;RPS27A;RPS4Y1;RPL6;RPL29;RPL14;RPS24;RPL37;RPL32;RPS11;RPL5;RPS25;RPS18;RPL18 | non-significant |
| KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS | 0.0078512 | 0.1318114 | 0.3807304 | 0.7442364 | 1.7330359 | 10 | HSD17B2;SRD5A3;HSD17B6;HSD3B1;SRD5A1;HSD3B2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_P27_CELL_CYCLE_G1_S | 0.0027952 | 0.0777494 | 0.4317077 | 0.8294369 | 1.7311686 | 7 | CCNE1;E2F1;CCNE2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_OUTER_KINETOCHORE | 0.0053713 | 0.0996580 | 0.4070179 | 0.6550176 | 1.7250308 | 16 | ZWINT;CDCA8;BIRC5;NDC80;NUF2;AURKB;INCENP;SPC25;SPC24 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0028889 | 0.0777494 | 0.4317077 | 0.8262258 | 1.7244665 | 7 | HLA-E;HLA-C;HLA-B;HLA-G;B2M;HLA-F;HLA-A | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_CDKN1B_TO_P27_CELL_CYCLE_G1_S | 0.0038868 | 0.0925361 | 0.4317077 | 0.7962770 | 1.7166889 | 8 | CCNE1;E2F1;CCNE2;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.0102855 | 0.1637641 | 0.3807304 | 0.6955688 | 1.7047560 | 12 | ERBB2;RPS6KB2;EGF;RPS6KB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0036722 | 0.0909225 | 0.4317077 | 0.8112163 | 1.6931392 | 7 | HLA-E;HLA-C;HLA-B;HLA-G;HLA-F;HLA-A | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING | 0.0123304 | 0.1734661 | 0.3807304 | 0.5651701 | 1.6610601 | 24 | CCNE1;CDC45;CCNE2;MCM4;CDT1;CCNA2;MCM5;DBF4;ORC6 | non-significant |
| KEGG_MEDICUS_REFERENCE_INACTIVATION_OF_CONDENSIN_I | 0.0045981 | 0.0981462 | 0.4070179 | 0.8317481 | 1.6607549 | 6 | NCAPD2;NCAPG;SMC4;NCAPH | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES | 0.0054739 | 0.0996580 | 0.4070179 | 0.8261787 | 1.6496345 | 6 | HLA-E;HLA-C;HLA-B;HLA-G;HLA-F;HLA-A | non-significant |
| KEGG_MEDICUS_REFERENCE_IL2_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0151759 | 0.1914478 | 0.3807304 | 0.5692994 | 1.6481225 | 23 | IL21R;STAT1;IL2RB;IL2RA;IL21;IL15RA;IL2RG;IL2;IL7R;IL7;IL4R;IL9;CRLF2;TSLP;IL4 | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_TERMINATION | 0.0141619 | 0.1914478 | 0.3807304 | 0.6033481 | 1.6407267 | 18 | CDC45;PIF1;VCP;MCM4;GINS1;RBX1;MCM5 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION | 0.0162035 | 0.1928835 | 0.3524879 | 0.5762377 | 1.6395238 | 22 | TUBA4A;KIF2C;AURKA;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C;AURKB | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCNE_TO_CELL_CYCLE_G1_S | 0.0067270 | 0.1189712 | 0.4070179 | 0.8193396 | 1.6359788 | 6 | CCNE1;E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY | 0.0103479 | 0.1637641 | 0.3807304 | 0.4874927 | 1.6314411 | 44 | IFNG;STAT1;EPO;IL12A;IL13;IL2RB;IFNAR2;IL2RA;IL23R;IL6;IL13RA1;IL15RA;IL5RA;IL2RG;IL2;IL6R;IFNGR1;IL7R;IL7;IL3;IL4R;JAK2;IL4;CSF2RB;IFNGR2;STAT4;IL5;IL12RB2;JAK3;IL15;STAT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 0.0229524 | 0.2277509 | 0.3524879 | 0.6463993 | 1.6238428 | 13 | DHCR7;DHCR24;MSMO1;SQLE;EBP;LSS;TM7SF2;LBR;NSDHL | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOLYSIS | 0.0189997 | 0.2138683 | 0.3524879 | 0.5606507 | 1.6230847 | 23 | PFKP;GPI;PGK1;LDHA;GAPDH;ENO1;LDHAL6B;PFKL;LDHC | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT | 0.0146601 | 0.1914478 | 0.3807304 | 0.5916747 | 1.6116417 | 19 | TUBA4A;CENPF;TUBB4B;TUBB1;TUBB3;TUBA1B;CENPE;TUBA1C;BUB1B | non-significant |
| KEGG_MEDICUS_REFERENCE_TRAIP_DEPENDENT_REPLISOME_DISASSEMBLY | 0.0154643 | 0.1914478 | 0.3807304 | 0.6190420 | 1.6020339 | 15 | CDC45;VCP;MCM4;GINS1;TRAIP;MCM5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE | 0.0183529 | 0.2138683 | 0.3524879 | 0.8335290 | 1.5976873 | 5 | C1QB;C1QA;C1QC | non-significant |
| KEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0151692 | 0.1914478 | 0.3807304 | 0.5166228 | 1.5895671 | 29 | NCF2;NCF1;CYBA;ATF4;NCF4;CYBB;CREB3L4;CREB3L2;CREB3L1;EGR1;MAPK1;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP | 0.0261799 | 0.2410547 | 0.3524879 | 0.5693409 | 1.5829618 | 20 | DUSP6;DUSP4;DUSP10;DUSP5;PTPN7;DUSP2;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_VCP_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0230427 | 0.2277509 | 0.3524879 | 0.4846783 | 1.5787006 | 39 | PSMD3;PSMB5;VCP;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;RPS27A;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;UBC;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1;UBA52 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0234157 | 0.2277509 | 0.3524879 | 0.8220841 | 1.5757501 | 5 | FUT3;FUT6;FUT4;FUT9;FUT5 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY | 0.0216978 | 0.2238494 | 0.3524879 | 0.5883526 | 1.5750913 | 17 | IRF5;TLR8;IFNA10;TLR9;IFNA21;IFNA5;IFNA2;MYD88;IFNA8;IFNA6;TLR7 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN | 0.0355892 | 0.2654186 | 0.3217759 | 0.6725261 | 1.5660507 | 10 | FGG;FGB;FGA;MBL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING | 0.0316651 | 0.2622362 | 0.3217759 | 0.5601619 | 1.5574409 | 20 | DNMT3B;KIF4A;NCAPD2;NCAPG;SMC4;NCAPH;TOP2A;NCAPG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0275675 | 0.2473082 | 0.3524879 | 0.4806792 | 1.5555502 | 38 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;RPS27A;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;UBC;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1;UBA52 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_UBQLN2_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0294305 | 0.2581187 | 0.3524879 | 0.4737820 | 1.5432091 | 39 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;RPS27A;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;UBC;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1;UBA52 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 0.0471545 | 0.3243180 | 0.2663507 | 0.6799626 | 1.5321440 | 9 | PIK3R3;PDCD1;CD274;PDCD1LG2;PIK3R2;PTPN11 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.0416667 | 0.2987233 | 0.2820134 | 0.5801996 | 1.5279929 | 16 | IFNG;STAT1;IL27;IFNA10;IFNGR1;IFNA21;IFNA5;IFNA2;JAK2;IFNA8;IFNA6;IFNGR2;IFNA16;STAT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0300235 | 0.2581187 | 0.3524879 | 0.4776813 | 1.5259775 | 35 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0377644 | 0.2775287 | 0.2878571 | 0.4646831 | 1.5242622 | 40 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;DERL1;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;RPS27A;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;UBC;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1;UBA52 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY | 0.0512821 | 0.3488307 | 0.2529611 | 0.5732241 | 1.5096225 | 16 | ERBB2;KRAS;EGF;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0381098 | 0.2775287 | 0.2878571 | 0.4720409 | 1.5079590 | 35 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1;PRNP | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY | 0.0549451 | 0.3618190 | 0.2413400 | 0.5087037 | 1.4951029 | 24 | ATF4;MAP2K3;RPS6KA5;CREB3L4;CREB3L2;CREB3L1;MAP2K6;RPS6KA4;CREB3L3;TAB1;CREB1;TRADD;CREB5;TRAF2;ATF2;MAPK14;TAB2;ATF6B;RIPK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VCYCLIN_TO_CELL_CYCLE_G1_S | 0.0540541 | 0.3597791 | 0.2529611 | 0.7422879 | 1.4821294 | 6 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS | 0.0574324 | 0.3742176 | 0.2450418 | 0.7370619 | 1.4716947 | 6 | FUT3;FUT6;FUT4;FUT5;FUT7 | non-significant |
| KEGG_MEDICUS_REFERENCE_II_BLOOD_GROUP_ANTIGEN_BIOSYNTHESIS | 0.0694915 | 0.4340549 | 0.2220560 | 0.6974408 | 1.4556715 | 7 | B3GNT3;B4GALT3;B3GNT2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.0753205 | 0.4500683 | 0.2065879 | 0.5522482 | 1.4543811 | 16 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION | 0.0651466 | 0.4177465 | 0.2249661 | 0.5110351 | 1.4540078 | 22 | TUBA4A;AURKA;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C;CLTC | non-significant |
| KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION | 0.0658784 | 0.4177465 | 0.2279872 | 0.7201041 | 1.4378348 | 6 | CDCA5;PDS5B;STAG1;STAG2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION | 0.0969793 | 0.4764302 | 0.1797823 | 0.5712203 | 1.4349829 | 13 | HLA-DRB1;HLA-DQB1;HLA-DOB;HLA-DRA;HLA-DMB;HLA-DRB5;HLA-DPB1;HLA-DMA;HLA-DPA1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PRNP_PI3K_NOX2_SIGNALING_PATHWAY | 0.0913462 | 0.4731730 | 0.1864326 | 0.5448611 | 1.4349268 | 16 | NCF2;NCF1;CYBA;NCF4;CYBB | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.0709459 | 0.4348073 | 0.2192503 | 0.7164438 | 1.4305263 | 6 | ATF4;EIF2AK3;EIF2S1;DDIT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1014493 | 0.4853996 | 0.1766943 | 0.6142485 | 1.4303449 | 10 | PLCB4;PLCB1;SPTBN2;GRM1;PLCB3;ITPR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY | 0.0881410 | 0.4731730 | 0.1900233 | 0.5511289 | 1.4262801 | 15 | IFNA10;IRF7;TLR9;IFNA21;IFNA5;IFNA2;MYD88;IFNA8;IFNA6;TLR7;IFNA16;IFNB1;IFNA4;IRAK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 0.0785256 | 0.4500683 | 0.2020717 | 0.5317721 | 1.4236185 | 17 | IL1R1;MAP2K3;ZFP36;IL1B;MAP2K6;IL1RAP;MYD88;TAB1;IL1A;MAPK14;TAB2;IRAK4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.0701220 | 0.4340549 | 0.2089550 | 0.4456214 | 1.4235606 | 35 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY | 0.1040650 | 0.4917272 | 0.1752040 | 0.6316871 | 1.4233660 | 9 | HIF1A;TGFB2;VEGFA | non-significant |
| KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY | 0.0765625 | 0.4500683 | 0.2020717 | 0.4724445 | 1.4155529 | 26 | IFNG;STAT1;IFNAR2;IFNA10;IFNGR1;IFNA21;IFNA5;IFNA2;JAK2;IFNA8;IFNA6;IFNGR2;STAT4;IFNA16;JAK3;STAT3;STAT2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY | 0.0915254 | 0.4731730 | 0.1918922 | 0.6777454 | 1.4145640 | 7 | PLCB4;PLCB1;CASR;PTH;PLCB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AHR_SIGNALING_PATHWAY | 0.0989761 | 0.4824111 | 0.1847065 | 0.6542471 | 1.4104875 | 8 | VEGFA;IL6;PTGS2;AHR;IL22;CYP1A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MODIFYING_OF_CONDENSIN_II_SUBUNITS | 0.0777027 | 0.4500683 | 0.2089550 | 0.7059397 | 1.4095528 | 6 | CDK1;NCAPG2;AURKB;PLK1;NCAPH2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_NSP1_TO_TRANSLATION_INITIATION | 0.0816641 | 0.4614959 | 0.1938133 | 0.4424208 | 1.4032200 | 34 | RPS5;RPS8;RPSA;RPS12;RPS19;RPS13;RPS6;RPS20;RPS10;RPS4Y2;RPS17;RPS27;RPS16;RPS4X;RPS3;RPS28;RPS7;RPS27A;RPS4Y1;RPS24;RPS11;RPS25;RPS18 | non-significant |
| KEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION | 0.0860215 | 0.4731730 | 0.1882041 | 0.4458008 | 1.3907413 | 31 | TUBA4A;TUBB4B;HAUS8;TUBB1;TUBB3;TUBA1B;TUBA1C;TPX2;HAUS3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 0.1257962 | 0.5333413 | 0.1563124 | 0.5411238 | 1.3895921 | 14 | CD19;PIK3R3;PIK3AP1;PIK3R2;SYK;LYN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 0.0955519 | 0.4731730 | 0.1847065 | 0.4927661 | 1.3851849 | 21 | PLCB4;SLC25A5;PLCB1;CHRM1;CHRM3;SLC25A31;CHRM5;VDAC2;CYCS;PLCB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES | 0.1351351 | 0.5525905 | 0.1501698 | 0.5512682 | 1.3848605 | 13 | HLA-DRB1;HLA-DQB1;HLA-DOB;HLA-DRA;HLA-DMB;HLA-DRB5;HLA-DPB1;HLA-DMA;HLA-DPA1;CD74;HLA-DOA | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.0945946 | 0.4731730 | 0.1882041 | 0.6927920 | 1.3833007 | 6 | HK3;HK2;HKDC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.0890625 | 0.4731730 | 0.1864326 | 0.4518435 | 1.3796475 | 28 | PLCB4;ATF4;PLCB1;CREB3L4;CREB3L2;CREB3L1;CYP11B2;CAMK1D;CREB3L3;CAMK1G;CAMK2D;CAMK2A;PLCB3;CREB1;CREB5;CALM2;ATF2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.1089744 | 0.5033965 | 0.1695706 | 0.5150041 | 1.3787284 | 17 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.0945946 | 0.4731730 | 0.1882041 | 0.6903444 | 1.3784136 | 6 | ATF4;EIF2AK3;EIF2S1;DDIT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 0.1160862 | 0.5075966 | 0.1669338 | 0.4952406 | 1.3769377 | 20 | PLCB4;SLC25A5;PLCB1;CHRM1;CHRM3;SLC25A31;CHRM5;VDAC2;CYCS;PLCB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY | 0.1160862 | 0.5075966 | 0.1669338 | 0.4941311 | 1.3738528 | 20 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION | 0.1062500 | 0.4945019 | 0.1695706 | 0.4577711 | 1.3715879 | 26 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C;TPX2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 0.1365854 | 0.5525905 | 0.1511488 | 0.6074950 | 1.3688545 | 9 | PIK3R3;ICOS;PIK3R2;ICOSLG | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY | 0.1172529 | 0.5075966 | 0.1669338 | 0.5020699 | 1.3675705 | 19 | STAT1;IFNAR2;IFNW1;IFNK;IFNA10;IFNA21;IFNA5;IFNA2;IFNA8;IFNA6;IFNA16;STAT2;IFNE;IFNB1;IFNA4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1351792 | 0.5525905 | 0.1521449 | 0.5752629 | 1.3654399 | 11 | PLCB4;PLCB1;GRM1;PLCB3;PRKCG;ITPR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY | 0.1433172 | 0.5614770 | 0.1464162 | 0.5833344 | 1.3583581 | 10 | CASP7;CASP8;CASP3;TRADD;TRAF2;FADD;RIPK1;TNF | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_ITPR1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1254237 | 0.5333413 | 0.1619789 | 0.6467625 | 1.3498976 | 7 | PLCB4;PLCB1;GRM1;PLCB3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.1165541 | 0.5075966 | 0.1682382 | 0.6746180 | 1.3470126 | 6 | PLCB4;PLCB1;PLCB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_UREA_CYCLE | 0.1165541 | 0.5075966 | 0.1682382 | 0.6742081 | 1.3461942 | 6 | ASS1;ARG2;OTC | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.1172638 | 0.5075966 | 0.1644058 | 0.4731137 | 1.3461132 | 22 | PLCB4;CASP7;SLC25A5;PLCB1;CASP3;SLC25A31;APAF1;VDAC2;CYCS;PLCB3;GRM5;ITPR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT | 0.1322034 | 0.5525905 | 0.1574029 | 0.6444487 | 1.3450685 | 7 | CP;TFRC;STEAP3;SLC39A8 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION | 0.1233108 | 0.5300652 | 0.1631801 | 0.6703629 | 1.3385165 | 6 | MYCN;MAX;MDM2 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.1405751 | 0.5577947 | 0.1473312 | 0.4598643 | 1.3313077 | 23 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY | 0.1356784 | 0.5525905 | 0.1541910 | 0.4886527 | 1.3310238 | 19 | IL1R1;FOS;IL1B;IL1RAP;MAPK10;MAPK9;MYD88;TAB1;IL1A;MAP2K4;JUN;TAB2;IRAK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY | 0.1359867 | 0.5525905 | 0.1531588 | 0.4781615 | 1.3294520 | 20 | ATF4;KRAS;CREB3L4;CREB3L2;CREB3L1;MAPK1;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY | 0.1671975 | 0.5895450 | 0.1335550 | 0.5164409 | 1.3262072 | 14 | IFNA10;IRF7;IFNA21;IFNA5;IFNA2;IFNA8;TRAF3;IFNA6;IFNA16;IKBKE;IFNA4;TBK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GRM1_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.1642276 | 0.5895450 | 0.1364904 | 0.5885213 | 1.3261014 | 9 | PLCB4;PLCB1;GRM1;PLCB3;ITPR3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.1405751 | 0.5577947 | 0.1473312 | 0.4571785 | 1.3235324 | 23 | ATF4;CREB3L4;CREB3L2;CREB3L1;CYP11B2;CAMK1D;CREB3L3;CAMK1G;CAMK2D;CAMK2A;CREB1;CREB5;CALM2;ATF2;ATP2B3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1 | 0.1690821 | 0.5895450 | 0.1335550 | 0.5672791 | 1.3209714 | 10 | WIPI1;WDR45B;NRBF2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION | 0.1587031 | 0.5895450 | 0.1429011 | 0.6122390 | 1.3199224 | 8 | PIF1;MCM4;MCM5;MCM7;MCM6;POLD3 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY | 0.1789137 | 0.5895450 | 0.1287887 | 0.5359148 | 1.3134629 | 12 | HIF1A;TGFB2;VEGFA;RBX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MEVALONATE_PATHWAY | 0.1789137 | 0.5895450 | 0.1287887 | 0.5358344 | 1.3132659 | 12 | HMGCS2;FDPS;HMGCS1;MVD;IDI1;GGPS1;ACAT2;MVK | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_SPRED_AND_NF1 | 0.1469595 | 0.5619099 | 0.1482615 | 0.6563314 | 1.3104998 | 6 | KRAS;SPRED2;SPRED1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY | 0.1453125 | 0.5619099 | 0.1429011 | 0.4277306 | 1.3060217 | 28 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY | 0.1699029 | 0.5895450 | 0.1335550 | 0.4788420 | 1.3021484 | 18 | STAT1;IFNAR2;IFNA10;IRF7;IFNA21;IFNA5;IFNA2;IFNA8;IFNA6;IFNA16;STAT2;IFNB1;IFNA4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.1774744 | 0.5895450 | 0.1342735 | 0.6028627 | 1.2997083 | 8 | BID;CASP8;CASP3;APAF1;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.1731392 | 0.5895450 | 0.1321473 | 0.4773343 | 1.2980484 | 18 | PLCB4;SLC25A5;PLCB1;SLC25A31;VDAC2;GRM1;CYCS;PLCB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY | 0.1775244 | 0.5895450 | 0.1307771 | 0.5466608 | 1.2975502 | 11 | HAMP;BMP6;ACVR1;SMAD5 | non-significant |
| KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH | 0.1647446 | 0.5895450 | 0.1372508 | 0.4585924 | 1.2891212 | 21 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY | 0.1629393 | 0.5895450 | 0.1357409 | 0.4445176 | 1.2868791 | 23 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY | 0.1640625 | 0.5895450 | 0.1335550 | 0.4278286 | 1.2818731 | 26 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS | 0.1691792 | 0.5895450 | 0.1364904 | 0.4700861 | 1.2804508 | 19 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT | 0.1709265 | 0.5895450 | 0.1321473 | 0.4422448 | 1.2802992 | 23 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;KIF5B;TUBA1C | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.1726845 | 0.5895450 | 0.1301056 | 0.4353341 | 1.2794663 | 24 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;KIF5B;TUBA1C | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS | 0.1954397 | 0.6168603 | 0.1238422 | 0.5376062 | 1.2760582 | 11 | BID;CASP8;CASP3;APAF1;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_ORIGIN_UNWINDING_AND_ELONGATION | 0.1499227 | 0.5682357 | 0.1395997 | 0.4129875 | 1.2752372 | 30 | CDC45;MCM10;MCM4;GINS1;MCM5;RFC3;RFC4;PRIM1;POLE2;RFC2;MCM7;WDHD1;MCM6;POLE3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.1693811 | 0.5895450 | 0.1342735 | 0.4464424 | 1.2702273 | 22 | PLCB4;SLC25A5;PLCB1;CASP3;SLC25A31;APAF1;VDAC2;CYCS;PLCB3;GRM5;ITPR3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_PERK_ATF4_SIGNALING_PATHWAY | 0.1790541 | 0.5895450 | 0.1328463 | 0.6360637 | 1.2700310 | 6 | ATF4;EIF2AK3;EIF2S1;DDIT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.1514683 | 0.5682357 | 0.1388051 | 0.4109108 | 1.2688246 | 30 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY | 0.2178060 | 0.6401527 | 0.1147507 | 0.5036012 | 1.2651146 | 13 | ACTR3;ARPC2;ARPC5L;ACTR2;ACTB;ARPC5;CDC42;ARPC1B;ARPC4;ARPC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE | 0.2179487 | 0.6401527 | 0.1152400 | 0.4847005 | 1.2543682 | 15 | CDK1;CDCA5;AURKB;PLK1;PPP2R1B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.1939587 | 0.6168603 | 0.1226792 | 0.4234800 | 1.2509012 | 25 | ATF4;CREB3L4;CREB3L2;CREB3L1;CYP11B2;CAMK1D;CREB3L3;CAMK1G;CAMK2D;CAMK2A;CREB1;CREB5;KCNJ5;CALM2;ATF2;CACNA1D;CALM3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY | 0.1959459 | 0.6168603 | 0.1262540 | 0.6241896 | 1.2463221 | 6 | MAP3K5;MAPK10;MAPK9 | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY | 0.2115385 | 0.6401527 | 0.1172497 | 0.4654592 | 1.2460907 | 17 | ACTR3;WIPF3;ARPC2;ARPC5L;ACTR2;ACTB;ARPC5;ARPC1B;NCK2;ARPC4;WIPF1;ARPC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.2163462 | 0.6401527 | 0.1157344 | 0.4718422 | 1.2426268 | 16 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;CREB1;PRKACB;PRKACG;CREB5;ATF2;ADCY5;DRD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PRE_IC_FORMATION | 0.1959565 | 0.6168603 | 0.1204334 | 0.4085597 | 1.2407957 | 27 | CDC45;MCM4;CDT1;GINS1;MCM5;ORC6;POLE2;ORC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY | 0.2356688 | 0.6661141 | 0.1096841 | 0.4825501 | 1.2391763 | 14 | UBE2T;FANCG;FANCA;FANCB;FANCD2;FANCE;FANCM | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.2166405 | 0.6401527 | 0.1142665 | 0.4188276 | 1.2309531 | 24 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;KIF5B;TUBA1C | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.2182104 | 0.6401527 | 0.1137873 | 0.4172328 | 1.2262658 | 24 | ATF4;CREB3L4;CREB3L2;CREB3L1;CYP11B2;CAMK1D;CREB3L3;CAMK1G;CAMK2D;CAMK2A;CREB1;CREB5;CALM2;ATF2;CACNA1D;CALM3 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_GLC_6P_TO_MAN_P_DOL | 0.2325203 | 0.6659295 | 0.1119183 | 0.5438815 | 1.2255155 | 9 | GPI;GMPPA;GMPPB | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY | 0.2436306 | 0.6676285 | 0.1075544 | 0.4769678 | 1.2248411 | 14 | ACTR3;ARPC2;ARPC5L;ACTR2;BAIAP2L1;ACTB;ARPC5;ARPC1B;ARPC4;ARPC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.2140625 | 0.6401527 | 0.1147507 | 0.4077726 | 1.2217809 | 26 | TLR2;MAP2K3;FOS;MAP2K6;MAPK1;MAPK10;MAPK9;MYD88;TLR4;MAP2K4;JUN;MAPK14;TAB2;IRAK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY | 0.2415459 | 0.6676285 | 0.1088201 | 0.5237831 | 1.2196862 | 10 | IL12A;IL23R;JAK2;STAT4;IL12RB2;STAT3;IL12RB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION | 0.2103659 | 0.6401527 | 0.1142665 | 0.3806149 | 1.2158941 | 35 | PSMD3;PSMB5;PSMD11;PSMD8;PSMA3;PSMD7;PSMD14;PSMC5;PSMA6;PSMA2;PSMB6;PSMD2;PSMB7;PSMC1;PSMB3;PSMD12;PSMD1;PSMA1;PSMA8;PSMA5;PSMB4;PSMD4;PSMB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY | 0.2338983 | 0.6659295 | 0.1142665 | 0.5814304 | 1.2135391 | 7 | MAP3K5;ERN1;MAPK10;MAPK9;TRAF2 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY | 0.2440273 | 0.6676285 | 0.1119183 | 0.5622486 | 1.2121485 | 8 | FCGR3A;FCGR3B;FCGR2A;RAC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY | 0.2024730 | 0.6235361 | 0.1177658 | 0.3911301 | 1.2077451 | 30 | ITGB6;ITGB7;ITGA11;FN1;ITGB4;ITGA8 | non-significant |
| KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY | 0.2557003 | 0.6678418 | 0.1059203 | 0.5065579 | 1.2023624 | 11 | IFNA10;IFNA21;IFNA5;IFNA2;IFNA8;IFNA6;IFNA16;IFNB1;IFNA4;TBK1;IRF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.2542662 | 0.6678418 | 0.1092500 | 0.5575331 | 1.2019822 | 8 | BLNK;BTK;SYK;LYN;ITPR3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR1_2_4_NFKB_SIGNALING_PATHWAY | 0.2388060 | 0.6676285 | 0.1114627 | 0.4307468 | 1.1976228 | 20 | TLR2;IL12A;IL6;NFKBIA;TLR1;MYD88;TLR4;CHUK;TAB2;IRAK4;TNF;TIRAP | non-significant |
| KEGG_MEDICUS_REFERENCE_COPII_VESICLE_FORMATION | 0.2587859 | 0.6730609 | 0.1039585 | 0.4885713 | 1.1974298 | 12 | SEC24A;SEC13;SEC24D;SEC24C;SAR1A;SEC23B;SEC23A | non-significant |
| KEGG_MEDICUS_REFERENCE_ORGANIZATION_OF_THE_INNER_KINETOCHORE | 0.2707006 | 0.6894431 | 0.1009906 | 0.4643099 | 1.1923360 | 14 | CENPA;CENPN;CENPI;CENPL;CENPM;CENPO | non-significant |
| KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY | 0.2707006 | 0.6894431 | 0.1009906 | 0.4641543 | 1.1919365 | 14 | ACTR3;ARPC2;ARPC5L;ACTR2;ABI1;ACTB;ARPC5;ARPC1B;ARPC4;ARPC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY | 0.2495812 | 0.6678418 | 0.1092500 | 0.4373806 | 1.1913656 | 19 | IFNA10;IRF7;IFIH1;IFNA21;IFNA5;IFNA2;IFNA8;TRAF3;IFNA6;IFNA16;AZI2;IKBKE;TANK;IFNB1;IFNA4;TBK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.2345277 | 0.6659295 | 0.1114627 | 0.4180550 | 1.1894591 | 22 | TUBA4A;CAPN2;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN | 0.2690355 | 0.6894431 | 0.1051251 | 0.6177086 | 1.1840083 | 5 | CD46;CD55 | non-significant |
| KEGG_MEDICUS_REFERENCE_COPI_VESICLE_FORMATION | 0.2539936 | 0.6678418 | 0.1051251 | 0.4081647 | 1.1816372 | 23 | KDELR2;KDELR3;COPB2;COPE;TMED3;ARF1;ARCN1;COPZ1;TMED10;TMED5;COPG1;KDELR1;TMED6;GBF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY | 0.2728814 | 0.6894431 | 0.1043440 | 0.5660500 | 1.1814377 | 7 | MAP3K5;FASLG;MAPK10;MAPK9 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY | 0.2448331 | 0.6676285 | 0.1071402 | 0.3996289 | 1.1804485 | 25 | ATF4;CREB3L4;CREB3L2;CREB3L1;CYP11B2;CAMK1D;CREB3L3;CAMK1G;CAMK2D;CAMK2A;CREB1;CREB5;CALM2;ATF2;CACNA1D;CALM3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY | 0.2781570 | 0.6999154 | 0.1035763 | 0.5472527 | 1.1798190 | 8 | MAP3K5;FOS;MAPK10;MAPK9;MAP2K4;JUN | non-significant |
| KEGG_MEDICUS_VARIANT_EREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.2834138 | 0.7045509 | 0.0988903 | 0.5059822 | 1.1782351 | 10 | RPS6KB2;RPS6KB1;EREG | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY | 0.2718447 | 0.6894431 | 0.1017139 | 0.4290979 | 1.1668760 | 18 | IFNA10;IRF7;IFNA21;IFNA5;IFNA2;IFNA8;TRAF3;IFNA6;IFNA16;AZI2;IKBKE;TANK;IFNB1;IFNA4;TBK1;IRF3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR | 0.2804054 | 0.7019909 | 0.1024494 | 0.5819779 | 1.1620378 | 6 | HFE;TFR2;ACVR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.2916667 | 0.7149810 | 0.0968878 | 0.4395432 | 1.1575653 | 16 | CASP7;SLC25A5;CASP3;SLC25A31;APAF1;VDAC2;CYCS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY | 0.2987220 | 0.7194901 | 0.0952880 | 0.4708340 | 1.1539579 | 12 | IFNA10;IFNA21;IFNA5;IFNA2;IFNA8;IFNA6;IFNA16;IFNB1;IFNA4;TNF | non-significant |
| KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.2922297 | 0.7149810 | 0.0999277 | 0.5777208 | 1.1535376 | 6 | MAP2K3;MAP2K6;MAP2K4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY | 0.3191126 | 0.7435265 | 0.0952880 | 0.5304527 | 1.1436000 | 8 | TGFBR1;MSTN | non-significant |
| KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS | 0.3310580 | 0.7561805 | 0.0931455 | 0.5283623 | 1.1390932 | 8 | CSGALNACT1;CSGALNACT2;CHPF | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.3299492 | 0.7561805 | 0.0928481 | 0.5905729 | 1.1319953 | 5 | FOS;MAPK10;MAPK9;JUN | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.2971246 | 0.7194901 | 0.0956031 | 0.3908923 | 1.1316337 | 23 | PLCB4;CASP7;SLC25A5;PLCB1;CASP3;SLC25A31;APAF1;VDAC2;CYCS;PLCB3;GRM5;ITPR3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_REPRESSION | 0.3175676 | 0.7435265 | 0.0949752 | 0.5661369 | 1.1304080 | 6 | MYCN;NTRK1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY | 0.3344710 | 0.7583793 | 0.0925529 | 0.5228026 | 1.1271070 | 8 | NQO1;AKR1A1;HMOX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.3338983 | 0.7583793 | 0.0922597 | 0.5331015 | 1.1126688 | 7 | C1QB;C1QA;C1QC;C2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD40_NFKB_SIGNALING_PATHWAY | 0.3474576 | 0.7774292 | 0.0899861 | 0.5301375 | 1.1064825 | 7 | TRAF3;CD40LG;TRAF2;CD40;CHUK;NFKB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_CANONICAL_INFLAMMASOME_SIGNALING_PATHWAY | 0.3525424 | 0.7812621 | 0.0891647 | 0.5283163 | 1.1026813 | 7 | IL18;IL1B;PYCARD;CASP1;CASP4;CASP5 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS | 0.3705584 | 0.7812621 | 0.0862866 | 0.5752676 | 1.1026584 | 5 | FUT2;B3GALT5;B3GALT1;B3GALT2;B3GNT5 | non-significant |
| KEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.3707317 | 0.7812621 | 0.0840746 | 0.4882302 | 1.1001178 | 9 | PROKR2;MAPK1;PROK1;PROKR1;GNAI3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY | 0.3106646 | 0.7367869 | 0.0911073 | 0.3562536 | 1.1000524 | 30 | CCL3;CCL4;CCL2;CCL1;PIK3CG;CCR8;GNB3;CCR3;GNGT2;PIK3R6 | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.3550489 | 0.7812621 | 0.0865400 | 0.4610646 | 1.0943797 | 11 | RPS6KB2;RPS6KB1;EREG | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION | 0.3738019 | 0.7812621 | 0.0826646 | 0.4438545 | 1.0878343 | 12 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;CREB1;CREB5;ATF2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3478964 | 0.7774292 | 0.0873098 | 0.3981254 | 1.0826502 | 18 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CCND1_TO_CELL_CYCLE_G1_S | 0.3682432 | 0.7812621 | 0.0865400 | 0.5412857 | 1.0807875 | 6 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_CELL_CYCLE_G1_S | 0.3750000 | 0.7812621 | 0.0855357 | 0.5390729 | 1.0763691 | 6 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY | 0.3745928 | 0.7812621 | 0.0835991 | 0.4512052 | 1.0709775 | 11 | KRAS;EGF;RALA;RALB;SOS2;GRB2;SOS1;NRAS;RALGDS | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION | 0.4016260 | 0.7872529 | 0.0797706 | 0.4748950 | 1.0700700 | 9 | IDH2;IDH1;CS | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY | 0.3942308 | 0.7846587 | 0.0799859 | 0.4060504 | 1.0693597 | 16 | FOS;MAPK10;MAPK9;TAB1;TRADD;TRAF2;MAP2K4;JUN;TAB2;RIPK1;TNF | non-significant |
| KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT | 0.3523957 | 0.7812621 | 0.0840746 | 0.3456395 | 1.0672779 | 30 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;KIF5B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY | 0.3827362 | 0.7844596 | 0.0824344 | 0.4493248 | 1.0665143 | 11 | PLCB4;PLCB1;KISS1R;PLCB3;PRKCG;PRKCB;KISS1 | non-significant |
| KEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION | 0.3843648 | 0.7844596 | 0.0822055 | 0.4489607 | 1.0656500 | 11 | GZMB;CSF2;HDAC2;IL3;ELANE | non-significant |
| KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY | 0.3852596 | 0.7844596 | 0.0835991 | 0.3912267 | 1.0656486 | 19 | VAV1;CD3D;CD3G;CD247;VAV2;LCP2;LCK;ZAP70;ITPR3;CD4;GRAP2;CD3E | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY | 0.3937397 | 0.7846587 | 0.0815265 | 0.3787690 | 1.0647344 | 21 | ACTR3;EGF;WIPF3;ARPC2;ARPC5L;ACTR2;ACTB;CTTN;ARPC5;ARPC1B;NCK2;ARPC4;WIPF1;ARPC3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR4_IRF3_7_SIGNALING_PATHWAY | 0.3924915 | 0.7846587 | 0.0835991 | 0.4933682 | 1.0636497 | 8 | IRF7;TRAF3;TLR4;IKBKE;IFNB1;TBK1;IRF3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3899676 | 0.7846587 | 0.0810802 | 0.3902582 | 1.0612563 | 18 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR5_NFKB_SIGNALING_PATHWAY | 0.3894231 | 0.7846587 | 0.0806388 | 0.3960704 | 1.0603285 | 17 | IL12A;IL6;NFKBIA;MYD88;CHUK;TAB2;TLR5;IRAK4;TNF | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3704293 | 0.7812621 | 0.0828962 | 0.3588402 | 1.0599642 | 25 | TUBA4A;TUBB4B;TUBB1;TUBB3;TUBA1B;KIF5B;TUBA1C | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY | 0.4203390 | 0.8030550 | 0.0795565 | 0.5075783 | 1.0593977 | 7 | STAT1;EGF | non-significant |
| KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY | 0.3926868 | 0.7846587 | 0.0797706 | 0.4209139 | 1.0573928 | 13 | PLCB4;PLCB1;GRM1;PLCB3;PRKCG;ITPR3;PRKCB | non-significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 0.3978328 | 0.7847072 | 0.0776799 | 0.3401750 | 1.0466651 | 29 | NDC1;NXT2;SEH1L;NUP43;NCBP1;NUP205;NUP155;SRSF7;NUP133;NUP188;SRSF3;RANBP2;NUP62;ALYREF;GLE1;NUP107;NUP35;NXT1;NUP88 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY | 0.4044369 | 0.7872529 | 0.0819779 | 0.4851484 | 1.0459285 | 8 | TGFBR1;TGFB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY | 0.4043210 | 0.7872529 | 0.0766747 | 0.3289227 | 1.0374197 | 33 | CLDN14;ACTR3;CLDN1;CLDN2;CLDN7;ARPC2;ARPC5L;CLDN9;ACTR2;CLDN22;CLDN16;CLDN17 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY | 0.4201278 | 0.8030550 | 0.0764767 | 0.4215179 | 1.0330898 | 12 | PLCB4;PLCB1;TSHR;PLCB3;PRKCG;TSHB;PRKCB;DUOX2 | non-significant |
| KEGG_MEDICUS_REFERENCE_METHIONINE_DEGRADATION | 0.4331723 | 0.8149959 | 0.0753094 | 0.4418913 | 1.0289923 | 10 | DNMT3B;GNMT;DNMT3A | non-significant |
| KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.4323484 | 0.8149959 | 0.0736213 | 0.3387326 | 1.0287309 | 27 | STAT1;OSM;IL13;IL27;IL6;IL13RA1;IL6R;IL31;IL31RA;IL4R;JAK2;IL11 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS | 0.4543919 | 0.8297008 | 0.0753094 | 0.5145675 | 1.0274392 | 6 | GBE1;UGP2;GYS2;GYG1;GYG2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY | 0.4422764 | 0.8221294 | 0.0747385 | 0.4557875 | 1.0270156 | 9 | E2F1;BIRC5;CDC25A | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 0.4331210 | 0.8149959 | 0.0747385 | 0.3954454 | 1.0154937 | 14 | BRCA2;BARD1;MCM8;BRIP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY | 0.4535256 | 0.8297008 | 0.0727141 | 0.3851704 | 1.0143710 | 16 | NFKBIA;IFNA10;IFNA21;IFNA5;IFNA2;IFNA8;IFNA6;IFNA16;CHUK;IFNB1;IFNA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY | 0.4388610 | 0.8198756 | 0.0766747 | 0.3723968 | 1.0143585 | 19 | PLCB4;CXCR4;PLCB1;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.4873096 | 0.8527089 | 0.0718276 | 0.5291258 | 1.0142150 | 5 | CASP3;APAF1;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST | 0.4397394 | 0.8198756 | 0.0751182 | 0.4259423 | 1.0110135 | 11 | STT3B;STT3A;RPN1;ALG10;DDOST;ALG8;RPN2 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT | 0.4357798 | 0.8174173 | 0.0723571 | 0.3081617 | 1.0104955 | 41 | TUBA4A;DYNLL2;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY | 0.4631410 | 0.8314343 | 0.0716527 | 0.3766354 | 1.0082987 | 17 | KRAS;IL6;MAPK1;NOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.4505119 | 0.8274982 | 0.0762797 | 0.4671122 | 1.0070445 | 8 | PROKR2;MAPK1;PROK1;GNAI3 | non-significant |
| KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY | 0.4634146 | 0.8314343 | 0.0723571 | 0.4460960 | 1.0051779 | 9 | SLC16A10;THRB;SLC16A2;MYH6;RXRG | non-significant |
| KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY | 0.4647436 | 0.8314343 | 0.0714786 | 0.3798713 | 1.0004155 | 16 | KRAS;IL6;MAPK1;NOS2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 0.4796610 | 0.8527089 | 0.0727141 | 0.4792342 | 1.0002390 | 7 | RPS6KB2;RPS6KB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY | 0.4578696 | 0.8314343 | 0.0718276 | 0.3959530 | 0.9946877 | 13 | IL10RA;IL10;IL24;IL26;IL19;IL22;STAT3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS | 0.5159129 | 0.8697293 | 0.0684715 | 0.5522798 | 0.9920379 | 4 | HSD11B1;CYP2A6 | non-significant |
| KEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC | 0.4871795 | 0.8527089 | 0.0691198 | 0.3703706 | 0.9915269 | 17 | CDC20;TRIP13;BUB1B;MAD2L1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY | 0.4662480 | 0.8317220 | 0.0702813 | 0.2890784 | 0.9874943 | 50 | CYSLTR1;PLCB4;CXCR4;PLCB1;CYSLTR2;CHRM1;CHRM3;HTR2C;LTB4R2;CCKAR;TRHR;TACR3;GRM1;NTSR1;PLCB3;AVPR1A;PTAFR;TACR1;HTR2A;GRM5;ITPR3;CHRM2;HRH1 | non-significant |
| KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.4967949 | 0.8599266 | 0.0681513 | 0.3810039 | 0.9860092 | 15 | VLDLR;RPS6KB2;RPS6KB1 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 0.4854369 | 0.8527089 | 0.0697793 | 0.3600220 | 0.9790329 | 18 | SLC25A5;CASP3;SLC25A31;GRIN1;APAF1;VDAC2;GRIN2B;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION | 0.5160745 | 0.8697293 | 0.0689567 | 0.5093115 | 0.9762354 | 5 | GLB1;GNS;HEXB;GALNS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.5064103 | 0.8691934 | 0.0672065 | 0.3644563 | 0.9756936 | 17 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;CREB1;CYP11B1;CREB5;ATF2;NR5A1 | non-significant |
| KEGG_MEDICUS_VARIANT_LOSS_OF_RASSF1_TO_RAS_RASSF1_SIGNALING_PATHWAY | 0.5135135 | 0.8697293 | 0.0691198 | 0.4882693 | 0.9749293 | 6 | KRAS;RASSF5;STK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY | 0.4902280 | 0.8527089 | 0.0696133 | 0.4105866 | 0.9745655 | 11 | KRAS;EGF;RASSF5;STK4;SOS2;GRB2;SOS1;RASSF1;NRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 0.4880546 | 0.8527089 | 0.0721798 | 0.4508879 | 0.9720666 | 8 | SLN;ATP2A1;PLN;ATP2A3;MLN;C4orf3 | non-significant |
| KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION | 0.5069124 | 0.8691934 | 0.0650878 | 0.3075843 | 0.9681515 | 32 | BRCA2;RAD54L;RAD51;BARD1;RFC3;RFC4;RAD54B;XRCC2;POLE2;XRCC3;RFC2;POLD3;POLE3;POLD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST | 0.4864865 | 0.8527089 | 0.0687943 | 0.3844278 | 0.9657348 | 13 | BMP6;BMP5;GREM1;BMP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY | 0.5296875 | 0.8790256 | 0.0637845 | 0.3152990 | 0.9627261 | 28 | GHRH;ATF4;CREB3L4;CREB3L2;CREB3L1;GH1;GH2;ADCY8;CREB3L3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.5255354 | 0.8751294 | 0.0667426 | 0.3395175 | 0.9543970 | 21 | PLCB4;CXCR4;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY | 0.5120773 | 0.8697293 | 0.0668966 | 0.4096271 | 0.9538615 | 10 | PLCB4;PLCB1;TACR3;PLCB3;PRKCG;PRKCB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY | 0.5525424 | 0.8906868 | 0.0656814 | 0.4557031 | 0.9511260 | 7 | IL2RB;IL2RG;IL2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY | 0.5238908 | 0.8751294 | 0.0686326 | 0.4390348 | 0.9465126 | 8 | PROKR2;MAPK1;PROKR1;GNAI3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTION_COUPLED_NER | 0.5546875 | 0.8918222 | 0.0615707 | 0.3081209 | 0.9408086 | 28 | POLR2H;POLR2J2;POLR2K;RBX1;POLR2I;POLR2D;GTF2H3;ERCC2;ERCC6 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5351438 | 0.8825400 | 0.0643583 | 0.3832471 | 0.9392928 | 12 | KRAS;FOS;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_NEIL_GLYCOSYLASE | 0.5382114 | 0.8836946 | 0.0649408 | 0.4167157 | 0.9389760 | 9 | TDP1;PARP2;PARP1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY | 0.5574324 | 0.8926225 | 0.0650878 | 0.4682789 | 0.9350145 | 6 | MAP3K5;MAPK10;MAPK9 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY | 0.5472637 | 0.8891992 | 0.0650878 | 0.3358655 | 0.9338206 | 20 | WASF3;ACTR3;ARPC2;ARPC5L;ACTR2;ABI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT | 0.5426829 | 0.8886792 | 0.0614364 | 0.2810548 | 0.9308529 | 42 | TUBA4A;DNAH11;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C;DNAH17;DNAH3 | non-significant |
| KEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.5667216 | 0.8926225 | 0.0630790 | 0.3311373 | 0.9308399 | 21 | CDC20;PTTG1;BUB1B;MAD2L1;PTTG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG7_TO_ALG11 | 0.5777027 | 0.9030252 | 0.0633597 | 0.4646263 | 0.9277213 | 6 | ALG2;ALG11;DPAGT1;ALG14;ALG13 | non-significant |
| KEGG_MEDICUS_VARIANT_DELETED_DMD_TO_DYSTROPHIN_ASSOCIATED_PROTEIN_COMPLEX | 0.5523349 | 0.8906868 | 0.0632191 | 0.3971360 | 0.9247747 | 10 | SNTG1;SNTB1;ACTB;SNTG2;DTNA | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY | 0.5612083 | 0.8926225 | 0.0618406 | 0.3646389 | 0.9160223 | 13 | ACTR3;ARPC2;ARPC5L;ACTR2;ACTB;CTTN;ARPC5;ARPC1B;ARPC4;ARPC3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION | 0.5659777 | 0.8926225 | 0.0614364 | 0.3637022 | 0.9136693 | 13 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;PPARGC1A;CREB1;CREB5;ATF2 | non-significant |
| KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.5797101 | 0.9038806 | 0.0609039 | 0.3900739 | 0.9083298 | 10 | RPS6KB2;RPS6KB1;PIK3CB;MTOR | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY | 0.6067588 | 0.9182976 | 0.0565300 | 0.2904748 | 0.9061790 | 31 | FGFR4;FGF19;RPS6KB2;RPS6KB1;FGF21;FGF5;FGF17;FGF16;FGF22;FGF4;PIK3CB;FGF6;FGF23 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5897436 | 0.9172143 | 0.0598603 | 0.3482205 | 0.9011683 | 15 | KRAS;EGF;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY | 0.5990415 | 0.9176949 | 0.0589694 | 0.3109984 | 0.9003407 | 23 | ATF4;KRAS;CREB3L4;CREB3L2;CREB3L1;MAPK1;CREB3L3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.6205288 | 0.9302737 | 0.0560596 | 0.2952132 | 0.8965624 | 27 | RASD1;ATF4;CREB3L4;CREB3L2;CREB3L1;ADCY8;CREB3L3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.6006390 | 0.9176949 | 0.0588438 | 0.3629717 | 0.8896003 | 12 | CXCR4;CCR5;GNAI3;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY | 0.6041335 | 0.9176949 | 0.0583453 | 0.3521011 | 0.8845257 | 13 | YWHAZ;MAPK1;YWHAH | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.6041335 | 0.9176949 | 0.0583453 | 0.3519730 | 0.8842039 | 13 | SLC25A5;CASP3;SLC25A31;APAF1;VDAC2;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.6294498 | 0.9302737 | 0.0572461 | 0.3244037 | 0.8821736 | 18 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;CREB1;CYP11B1;CREB5;ATF2;NR5A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ASSEMBLY_AND_TRAFFICKING_OF_TELOMERASE | 0.6326861 | 0.9302737 | 0.0570060 | 0.3238430 | 0.8806489 | 18 | TERT;NAF1;CCT4;NOP10;DKC1;CCT6B;GAR1;RUVBL1;CCT2;WRAP53;CCT5;CCT6A | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_MESP2_SIGNALING | 0.6311337 | 0.9302737 | 0.0592219 | 0.4583193 | 0.8784948 | 5 | LFNG;TBX6;EPHA4;RIPPLY2 | non-significant |
| KEGG_MEDICUS_REFERENCE_DYNEIN_RECRUITMENT_TO_THE_KINETOCHORE | 0.6476043 | 0.9302737 | 0.0537873 | 0.2825392 | 0.8724343 | 30 | DYNLL2;CENPF;BUB1;ZWILCH;ACTR10 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY | 0.6343750 | 0.9302737 | 0.0552496 | 0.2898420 | 0.8684335 | 26 | PLCB4;CCL5;PLCB1;CCR5 | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.6448911 | 0.9302737 | 0.0577309 | 0.3184346 | 0.8673728 | 19 | SLC25A5;CASP3;SLC25A31;APAF1;VDAC2;RYR2;CYCS | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR | 0.6655405 | 0.9309071 | 0.0566484 | 0.4336865 | 0.8659436 | 6 | CFHR2;CFHR1;CFHR4;CFHR5 | non-significant |
| KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.6410256 | 0.9302737 | 0.0559429 | 0.3336962 | 0.8635807 | 15 | KRAS;EREG;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_STRAD_STK11_TSC_SIGNALING_PATHWAY | 0.6706485 | 0.9328795 | 0.0567672 | 0.3981961 | 0.8584687 | 8 | PRKAA2;PRKAA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BILE_ACID_BIOSYNTHESIS | 0.6496815 | 0.9302737 | 0.0550211 | 0.3339850 | 0.8576651 | 14 | ACOX2;CYP7B1;CYP27A1;AKR1D1;CYP39A1;CYP7A1;AKR1C4;CYP8B1 | non-significant |
| KEGG_MEDICUS_REFERENCE_V_D_J_RECOMBINATION | 0.6453674 | 0.9302737 | 0.0554793 | 0.3496113 | 0.8568555 | 12 | XRCC6;LIG4;RAG2;DCLRE1C;XRCC4;RAG1;XRCC5 | non-significant |
| KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY | 0.6625954 | 0.9309071 | 0.0521630 | 0.2465312 | 0.8557105 | 54 | ERBB2;FGFR4;MST1R;FGF19;VEGFA;EGF;FGF21;FGF5 | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP | 0.6471545 | 0.9302737 | 0.0561767 | 0.3789329 | 0.8538408 | 9 | PNP;LACC1;NT5C1A;NT5C2;NT5C1B | non-significant |
| KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 0.6875000 | 0.9419275 | 0.0551352 | 0.4275096 | 0.8536102 | 6 | CACNA1S;CACNA1B;CACNA1D;PRNP;CACNA1F | non-significant |
| KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066 | 0.6550079 | 0.9304798 | 0.0545681 | 0.3384303 | 0.8501829 | 13 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S | 0.6553945 | 0.9304798 | 0.0551352 | 0.3641526 | 0.8479692 | 10 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY | 0.6743472 | 0.9359213 | 0.0516356 | 0.2717656 | 0.8478130 | 31 | HIF1A;VEGFA;KRAS;FOS;MAPK1;GNB3 | non-significant |
| KEGG_MEDICUS_REFERENCE_N_GLYCAN_BIOSYNTHESIS | 0.6522436 | 0.9302737 | 0.0551352 | 0.3217639 | 0.8473858 | 16 | ST6GAL1;B4GALT3;B4GALT2;MGAT2;GANAB;B4GALT1;MGAT1;MAN1B1;MOGS | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH | 0.6942568 | 0.9424068 | 0.0546808 | 0.4242319 | 0.8470656 | 6 | PLAU;MASP1;MASP2;SERPING1 | non-significant |
| KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 0.6805112 | 0.9381657 | 0.0530213 | 0.2925642 | 0.8469739 | 23 | CASP7;SLC25A5;CASP3;SLC25A31;CACNA1S;APAF1;VDAC2;CYCS;CACNA1E | non-significant |
| KEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP | 0.6585366 | 0.9309071 | 0.0553643 | 0.3746938 | 0.8442888 | 9 | PNP;LACC1;NT5C1A;NT5C2;NT5C1B | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6677266 | 0.9309071 | 0.0536770 | 0.3350161 | 0.8416059 | 13 | SIX1;SIX4;HOXA11;HOXA9;HOXA10 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 0.6650641 | 0.9309071 | 0.0542316 | 0.3237145 | 0.8377486 | 15 | SLC25A5;SLC25A31;GRIN1;VDAC2;GRIN2B;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 0.6666667 | 0.9309071 | 0.0543434 | 0.3589049 | 0.8357493 | 10 | SLC25A5;SLC25A31;VDAC2;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S | 0.6789137 | 0.9381657 | 0.0531298 | 0.3399649 | 0.8332133 | 12 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S | 0.6945392 | 0.9424068 | 0.0551352 | 0.3859351 | 0.8320353 | 8 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY | 0.6910569 | 0.9424068 | 0.0531298 | 0.3670893 | 0.8271538 | 9 | CXCR4;RHOA;GNA12;ROCK2;ROCK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S | 0.6926829 | 0.9424068 | 0.0530213 | 0.3658603 | 0.8243846 | 9 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT | 0.7373272 | 0.9487678 | 0.0475434 | 0.2462432 | 0.8240767 | 44 | TUBA4A;DNAH11;TUBB4B;TUBB1;TUBB3;TUBA1B;TUBA1C;DNAH17;DNAH3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7019231 | 0.9465876 | 0.0517405 | 0.3109299 | 0.8188539 | 16 | KRAS;RPS6KA5;MAPK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY | 0.7044728 | 0.9465876 | 0.0514265 | 0.3327858 | 0.8156182 | 12 | CCL2;NFKBIA;BIRC3;TRAF2;TNFRSF14;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY | 0.7150171 | 0.9487678 | 0.0537873 | 0.3778547 | 0.8146147 | 8 | CYBB;IL6;VCAM1;MMP9 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RAS_UBIQUITINATION_BY_CUL3_COMPLEX | 0.7331081 | 0.9487678 | 0.0521630 | 0.4077733 | 0.8142026 | 6 | KRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY | 0.7381757 | 0.9487678 | 0.0518458 | 0.4042310 | 0.8071297 | 6 | IL18;IL1B;PYCARD | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S | 0.7263844 | 0.9487678 | 0.0509083 | 0.3395495 | 0.8059522 | 11 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY | 0.7163462 | 0.9487678 | 0.0508054 | 0.3006564 | 0.8048937 | 17 | EPO;GH1;PRL;GH2;JAK2;MPL;CSF3R;STAT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY | 0.7300813 | 0.9487678 | 0.0506004 | 0.3542445 | 0.7982111 | 9 | LPAR3;RHOA;LPAR2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.7712519 | 0.9545496 | 0.0457704 | 0.2584504 | 0.7980522 | 30 | WASF3;ACTR3;PIK3CG;ARPC2;ARPC5L;ARF1;ACTR2;ABI1;ACTB;PIK3CB;CYTH1;ARPC5;ARPC1B;CYTH4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY | 0.7638889 | 0.9545496 | 0.0461379 | 0.2511744 | 0.7922022 | 33 | ATF4;CREB3L4;CREB3L2;CREB3L1;MAP2K6;GNB3;CREB3L3;GNGT2;RHOA;GNB1;CREB1;CREB5;ATF2 | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE | 0.7307692 | 0.9487678 | 0.0498907 | 0.2998385 | 0.7896438 | 16 | CDC20;PTTG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY | 0.7360406 | 0.9487678 | 0.0520570 | 0.4116820 | 0.7891016 | 5 | E2F1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.7615262 | 0.9545496 | 0.0476387 | 0.2666215 | 0.7875629 | 25 | WASF3;ACTR3;ARPC2;ARPC5L;ARF1;ACTR2;ABI1;ACTB;CYTH1;ARPC5;ARPC1B;CYTH4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 0.7308917 | 0.9487678 | 0.0495902 | 0.3065312 | 0.7871644 | 14 | SLC25A5;SLC25A31;CACNA1S;VDAC2;CYCS;CACNA1D;SLC25A6;MCU;CACNA1F | non-significant |
| KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING | 0.7387821 | 0.9487678 | 0.0493910 | 0.2980785 | 0.7850088 | 16 | CDC20;PTTG1;PTTG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING | 0.7759473 | 0.9545496 | 0.0484088 | 0.2789510 | 0.7841422 | 21 | ASPH;CACNB4;CACNB1;CACNG7;RYR2;CACNG2;CACNG5 | non-significant |
| KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING | 0.7808896 | 0.9545496 | 0.0481184 | 0.2778741 | 0.7811149 | 21 | ASPH;CACNB4;CACNA1S;CACNB1;CACNG7;CACNG2;CACNG5 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_BIFUNCTIONAL_GLYCOSYLASE | 0.7713311 | 0.9545496 | 0.0502948 | 0.3550339 | 0.7654155 | 8 | PARP2;PARP1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY | 0.7987616 | 0.9545496 | 0.0442407 | 0.2480257 | 0.7631360 | 29 | WASF3;ACTR3;ARPC2;ARPC5L;ARF1;ACTR2;ABI1;ACTB;PIK3CB;NCKAP1L;CYTH1;ARPC5;ARPC1B;CYTH4 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY | 0.7756410 | 0.9545496 | 0.0471642 | 0.2921042 | 0.7559436 | 15 | EGF;CAMK1D;CAMK1G;CAMK2D;CAMK2A;CALM2;CALM3;CAMK2G;PLCG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_RASGAP | 0.7798635 | 0.9545496 | 0.0497903 | 0.3503730 | 0.7553672 | 8 | RASAL1;KRAS;RASA2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.8059701 | 0.9545496 | 0.0469759 | 0.2706328 | 0.7524513 | 20 | ATF4;CREB3L4;CREB3L2;CREB3L1;CREB3L3;CREB1;CYP11B1;CREB5;ATF2;NR5A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY | 0.7745572 | 0.9545496 | 0.0474483 | 0.3221596 | 0.7501838 | 10 | MAP3K9;MAPK10;MAP3K13;MAPK9;MAP2K4 | non-significant |
| KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S | 0.7852564 | 0.9545496 | 0.0466015 | 0.2884539 | 0.7464969 | 15 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY | 0.7949126 | 0.9545496 | 0.0456790 | 0.2962264 | 0.7441609 | 13 | KRAS;EGF;MAPK10;MAPK9;MAP2K4;SOS2;GRB2;SOS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_FKTN_TO_LARGE | 0.8521127 | 0.9590141 | 0.0471642 | 0.4972357 | 0.7438924 | 2 | FKTN;FKRP | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_P15_CELL_CYCLE_G1_S | 0.7965024 | 0.9545496 | 0.0455878 | 0.2959880 | 0.7435621 | 13 | E2F1;E2F2;E2F3 | non-significant |
| KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8399390 | 0.9568901 | 0.0412376 | 0.2324838 | 0.7426816 | 35 | FGFR4;FGF19;KRAS;FGF21;FGF5;MAPK1;FGF17;FGF16;FGF22;FGF4;FGF6;FGF23 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKR_EIF2ALPHA_SIGNALING_PATHWAY | 0.7915254 | 0.9545496 | 0.0487990 | 0.3527617 | 0.7362707 | 7 | EIF2S1;EIF2AK2;EIF2B4;EIF2B5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY | 0.8016260 | 0.9545496 | 0.0463228 | 0.3234323 | 0.7287825 | 9 | MYL12A;MYL12B;RHOA;MYL2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 0.8076312 | 0.9545496 | 0.0449543 | 0.2898805 | 0.7282191 | 13 | SLC25A5;SLC25A31;VDAC2;CYCS;ITPR3;SLC25A6;MCU | non-significant |
| KEGG_MEDICUS_REFERENCE_LONG_PATCH_BER | 0.8141026 | 0.9545496 | 0.0449543 | 0.2716379 | 0.7272075 | 17 | RFC3;RFC4;POLE2;RFC2;POLD3;POLE3;POLD1;POLB;LIG1;POLD4 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 0.8341709 | 0.9568901 | 0.0458620 | 0.2667098 | 0.7264815 | 19 | SLC25A5;CASP3;SLC25A31;GRIN1;APAF1;VDAC2;GRIN2B | non-significant |
| KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.8083067 | 0.9545496 | 0.0451344 | 0.2962596 | 0.7260969 | 12 | PLCB4;PLCB1;TRHR;PLCB3;PRKCG;TSHB;PRKCB | non-significant |
| KEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR | 0.8359375 | 0.9568901 | 0.0425878 | 0.2420556 | 0.7252544 | 26 | EXO1;RFC3;RFC4;POLE2;MLH1;RFC2;PMS1;POLD3;POLE3;POLD1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BASE_EXCISION_AND_STRAND_CLEAVAGE_BY_MONOFUNCTIONAL_GLYCOSYLASE | 0.8122867 | 0.9545496 | 0.0479259 | 0.3358482 | 0.7240533 | 8 | UNG;TDG;MBD4;POLB;MUTYH;APEX1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY | 0.8203883 | 0.9545496 | 0.0450443 | 0.2650644 | 0.7208082 | 18 | PLCB4;PLCB1;PTGS2;PLCB3;PPP3R2;CALM2 | non-significant |
| KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY | 0.7987118 | 0.9545496 | 0.0460458 | 0.3095334 | 0.7207824 | 10 | RPS6KA5;MAPK1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY | 0.8083736 | 0.9545496 | 0.0454968 | 0.3080508 | 0.7173300 | 10 | MYL12A;MYL12B;RHOA;MYL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA | 0.8174061 | 0.9545496 | 0.0476387 | 0.3326412 | 0.7171392 | 8 | TGFB2;PLG | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 0.8301282 | 0.9568901 | 0.0440640 | 0.2765022 | 0.7155667 | 15 | KRAS;EGF | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_E2_TO_NOD_NFKB_SIGNALING_PATHWAY | 0.8162602 | 0.9545496 | 0.0454968 | 0.3167970 | 0.7138313 | 9 | NFKBIA;RIPK2;CDC42;NOD1;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL | 0.8306189 | 0.9568901 | 0.0447749 | 0.2963439 | 0.7033999 | 11 | P2RX7;P2RX1;GRIN1;P2RX3;P2RX6 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 0.8322476 | 0.9568901 | 0.0446854 | 0.2948196 | 0.6997818 | 11 | RPS6KB2;RPS6KB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_NFKB_SIGNALING_PATHWAY | 0.8322476 | 0.9568901 | 0.0446854 | 0.2947356 | 0.6995822 | 11 | NFKBIA;TAB1;TRADD;CHUK;TAB2 | non-significant |
| KEGG_MEDICUS_VARIANT_DAB1_OVEREXPRESSION_TO_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 0.8390244 | 0.9568901 | 0.0442407 | 0.3091885 | 0.6966872 | 9 | VLDLR;PIK3CB;RELN;PIK3CD;AKT1;DAB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8429487 | 0.9568901 | 0.0433637 | 0.2631840 | 0.6931119 | 16 | KRAS;EGF;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 0.8410175 | 0.9568901 | 0.0431037 | 0.2756755 | 0.6925343 | 13 | RPS6KB2;RPS6KB1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_NEF_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.8471338 | 0.9568901 | 0.0428451 | 0.2670535 | 0.6857866 | 14 | NFKBIA;TAB1;TRADD;TRAF2;CHUK;TAB2;RIPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.9078341 | 0.9808677 | 0.0380056 | 0.2179529 | 0.6799363 | 31 | PLCB4;CXCR4;PLCB1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.8601626 | 0.9610842 | 0.0431037 | 0.2991516 | 0.6740714 | 9 | UQCRFS1;UQCRH;UQCR10;UQCRC1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 0.8537361 | 0.9590973 | 0.0424170 | 0.2680812 | 0.6734563 | 13 | SLC25A5;SLC25A31;VDAC2;CYCS;ITPR3;SLC25A6;MCU | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 0.8582931 | 0.9607295 | 0.0427591 | 0.2874793 | 0.6694271 | 10 | BIRC5;PIK3CB;MTOR;PIK3CD;AKT1;RELA | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.8701923 | 0.9687932 | 0.0419082 | 0.2576857 | 0.6668712 | 15 | NFKBIA;TAB1;TRADD;TRAF2;CHUK;TAB2;RIPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY | 0.8994975 | 0.9808677 | 0.0424170 | 0.2445643 | 0.6661600 | 19 | BMP6;BMP5;BMP7 | non-significant |
| KEGG_MEDICUS_REFERENCE_HYDROLYSIS_OF_SPHINGOMYELIN | 0.8762712 | 0.9725729 | 0.0441523 | 0.3148239 | 0.6570884 | 7 | SMPD2;ASAH2;ACER1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY | 0.8962109 | 0.9808677 | 0.0418239 | 0.2328580 | 0.6545730 | 21 | PLCB4;PLCB1;GNRHR;MAPK1;PLCB3;ELK1;FSHB;PRKCG;PRKCB | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA2_TO_RBP_JK_MEDIATED_TRANSCRIPTION | 0.8847458 | 0.9744798 | 0.0437126 | 0.3121300 | 0.6514657 | 7 | HES1;RUNX3;FCER2;SNW1;CR2 | non-significant |
| KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8794788 | 0.9725729 | 0.0421619 | 0.2722617 | 0.6462385 | 11 | KRAS;MAPK1;NTRK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES | 0.9252782 | 0.9899868 | 0.0387167 | 0.2183767 | 0.6450544 | 25 | JARID2;EZH2;HDAC2;AEBP2;CBX3;SUZ12;L3MBTL2;PCGF6;WDR5;EHMT1;MGA;MAX;EED;RYBP | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_NFKB_SIGNALING_PATHWAY | 0.8878205 | 0.9761295 | 0.0409884 | 0.2438733 | 0.6422559 | 16 | NFKBIA;TAB1;TRADD;TRAF2;CHUK;TAB2;RIPK1;TNF | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.8917197 | 0.9786782 | 0.0404935 | 0.2490914 | 0.6396604 | 14 | EGF;NFKBIA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050 | 0.9003378 | 0.9808677 | 0.0427591 | 0.3179083 | 0.6347689 | 6 | CASP3;APAF1;CYCS | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9044586 | 0.9808677 | 0.0398407 | 0.2437238 | 0.6258765 | 14 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.8993174 | 0.9808677 | 0.0432769 | 0.2892392 | 0.6235691 | 8 | EGF;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_LIGHT_HVEM_NFKB_SIGNALING_PATHWAY | 0.9033816 | 0.9808677 | 0.0404114 | 0.2661696 | 0.6198049 | 10 | NFKBIA;TNFSF14;TRAF2;TNFRSF14;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM | 0.9086294 | 0.9808677 | 0.0424170 | 0.3215759 | 0.6163886 | 5 | GRIN1;GRIN2B | non-significant |
| KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION | 0.9153976 | 0.9854454 | 0.0420772 | 0.3195856 | 0.6125736 | 5 | HPD;GSTZ1;FAH;HGD | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.9278846 | 0.9899868 | 0.0389556 | 0.2352700 | 0.6088611 | 15 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY | 0.9089431 | 0.9808677 | 0.0405756 | 0.2677813 | 0.6033854 | 9 | GDF2;BMP10;SMAD5;ACVR2A | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9187898 | 0.9873800 | 0.0391155 | 0.2343090 | 0.6016995 | 14 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUCONEOGENESIS | 0.9340102 | 0.9899868 | 0.0411544 | 0.3059760 | 0.5864870 | 5 | PCK2;MDH2 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOD_NFKB_SIGNALING_PATHWAY | 0.9219512 | 0.9890603 | 0.0399219 | 0.2587225 | 0.5829734 | 9 | NFKBIA;RIPK2;NOD1;CHUK | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9299363 | 0.9899868 | 0.0385579 | 0.2265101 | 0.5816721 | 14 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9331210 | 0.9899868 | 0.0383996 | 0.2244298 | 0.5763301 | 14 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_REFERENCE_C9ORF72_MEDIATED_AUTOPHAGY_INITIATION | 0.9322034 | 0.9899868 | 0.0413210 | 0.2759912 | 0.5760382 | 7 | RAB1A;C9orf72 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.9378981 | 0.9907149 | 0.0381629 | 0.2226122 | 0.5716625 | 14 | CAMK1D;CAMK1G;CAMK2D;CAMK2A;CALM2;CALM3;CAMK2G;PLCG2;CAMK4 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS | 0.9543919 | 0.9928884 | 0.0400846 | 0.2841808 | 0.5674250 | 6 | B4GALT3;B4GALT2;B4GALT1;B3GNT5 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION | 0.9376997 | 0.9907149 | 0.0383206 | 0.2306092 | 0.5651956 | 12 | ATG5;ATG16L1;MAP1LC3C;ATG12;ATG4A;MAP1LC3B | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY | 0.9498382 | 0.9928884 | 0.0383206 | 0.2060865 | 0.5604253 | 18 | CAMKK1;CAMK1D;CAMK1G;CAMK2D | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 0.9536741 | 0.9928884 | 0.0375363 | 0.2224813 | 0.5452750 | 12 | CXCR4;GNAI3;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY | 0.9597424 | 0.9936433 | 0.0376143 | 0.2305696 | 0.5369065 | 10 | NFKBIA;CHUK | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY | 0.9633758 | 0.9938827 | 0.0369161 | 0.2082096 | 0.5346770 | 14 | CAMK1D;CAMK1G;CAMK2D;CAMK2A;CALM2;CALM3;CAMK2G;PLCG2;CAMK4 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY | 0.9695946 | 0.9986340 | 0.0393562 | 0.2673208 | 0.5337606 | 6 | MAPK1;MAPK14 | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY | 0.9615385 | 0.9936433 | 0.0373030 | 0.2052098 | 0.5310674 | 15 | KRAS;MAPK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION | 0.9729730 | 0.9993770 | 0.0391956 | 0.2655508 | 0.5302263 | 6 | GRM1;ATXN1;ITPR1;SLC1A6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_NFKB_SIGNALING_PATHWAY | 0.9763514 | 1.0000000 | 0.0390355 | 0.2632474 | 0.5256272 | 6 | NFKBIA;CHUK;RELA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM | 0.9847973 | 1.0000000 | 0.0386372 | 0.2565864 | 0.5123272 | 6 | GRIN1;GRIN2B;PDYN | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION | 0.9795222 | 1.0000000 | 0.0393562 | 0.2352900 | 0.5072604 | 8 | PYGB;G6PC2;PGM1;PGM2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRAPPI_RAB1_SIGNALING_PATHWAY | 0.9788618 | 1.0000000 | 0.0371479 | 0.2148414 | 0.4840971 | 9 | TRAPPC6B;RAB1A;TRAPPC4 | non-significant |
| KEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX | 0.9914676 | 1.0000000 | 0.0387962 | 0.2178193 | 0.4695953 | 8 | RAD18;RNF168 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_K15_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.9931741 | 1.0000000 | 0.0387167 | 0.2119079 | 0.4568511 | 8 | NFKBIA;TRAF2;CHUK | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VFLIP_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.9847458 | 1.0000000 | 0.0387962 | 0.2169259 | 0.4527593 | 7 | NFKBIA;TRAF2;CHUK | non-significant |
| KEGG_MEDICUS_REFERENCE_TELOMERE_ELONGATION | 0.9947090 | 1.0000000 | 0.0588438 | -0.1519023 | -0.4344545 | 16 | ACD;TERF2IP;TERF2;TERF1;TINF2;NHP2;RUVBL2;POT1;CTC1;WRAP53;RUVBL1;GAR1;DKC1;NOP10;RTEL1;TERT | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY | 1.0000000 | 1.0000000 | 0.0585938 | -0.1498563 | -0.4380062 | 17 | PDGFRB;CAMK2B;CAMK1;PLCG1 | non-significant |
| KEGG_MEDICUS_REFERENCE_MITOCHONDRIAL_COMPLEX_UCP1_IN_THERMOGENESIS | 0.9970501 | 1.0000000 | 0.0639272 | -0.1170245 | -0.4506011 | 56 | NDUFAF1;NDUFB10;NDUFA2;NDUFAF2;CYC1;COA3;COA5;NDUFS3;UQCRC2;COX14;NDUFS4;NDUFA12;NDUFAF5;SDHC;NDUFA13 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_I | 1.0000000 | 1.0000000 | 0.0618406 | -0.1309451 | -0.4553916 | 38 | NDUFA7;NDUFB10;NDUFA2;NDUFAB1;NDUFS3;NDUFC1;NDUFS4;NDUFA12;NDUFB5;NDUFB2;NDUFA13;NDUFA5;NDUFS7;NDUFB11;NDUFA1;NDUFC2;NDUFB6;NDUFA4;NDUFA8;NDUFA10;NDUFB8;NDUFS5;NDUFA9;NDUFB7;NDUFB4;NDUFA3;NDUFB1;NDUFS2;NDUFS8;NDUFB3;NDUFV1;NDUFA6;NDUFV2;NDUFA11;NDUFS6;NDUFV3;NDUFS1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TDP43_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 1.0000000 | 1.0000000 | 0.0632191 | -0.1325973 | -0.4645402 | 39 | NDUFA7;NDUFB10;NDUFA2;NDUFAB1;NDUFS3;NDUFC1;NDUFS4;NDUFA12;NDUFB5;NDUFB2;NDUFA13;NDUFA5;NDUFS7;NDUFB11;NDUFA1;NDUFC2;NDUFB6;NDUFA4;NDUFA8;NDUFA10;NDUFB8;NDUFS5;NDUFA9;NDUFB7;NDUFB4;NDUFA3;TARDBP;NDUFB1;NDUFS2;NDUFS8;NDUFB3;NDUFV1;NDUFA6;NDUFV2;NDUFA11;NDUFS6;NDUFV3;NDUFS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY | 0.9892761 | 1.0000000 | 0.0597318 | -0.1758473 | -0.4725397 | 13 | ARHGEF11 | non-significant |
| KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING | 0.9892761 | 1.0000000 | 0.0597318 | -0.1772169 | -0.4762201 | 13 | PAXIP1;TP53BP1;POLL | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 0.9735450 | 0.9993770 | 0.0598603 | -0.1940703 | -0.5428940 | 15 | FLT3;PIK3CA;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS | 0.9536082 | 0.9928884 | 0.0596037 | -0.2140933 | -0.5456317 | 11 | GPX2;GCLC;GCLM;GPX7;GSS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.9912536 | 1.0000000 | 0.0636424 | -0.1578044 | -0.5528506 | 39 | NDUFA7;NDUFB10;NDUFA2;SNCA;NDUFAB1;NDUFS3;NDUFC1;NDUFS4;NDUFA12;NDUFB5;NDUFB2;NDUFA13;NDUFA5 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ANXA2_S100A10_REGULATED_ACTIN_CYTOSKELETON | 0.9440389 | 0.9928884 | 0.0573667 | -0.2781325 | -0.5638779 | 5 | AHNAK;ACTG1;S100A10;ANXA2;ACTB | non-significant |
| KEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING | 0.9512195 | 0.9928884 | 0.0571259 | -0.2616323 | -0.5645907 | 6 | MAPK3;RPS6KA3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9603175 | 0.9936433 | 0.0605093 | -0.2027919 | -0.5672919 | 15 | ARAF;MAPK3;HRAS;FGFR1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E7_TO_PP2A_AKT_SIGNALING_PATYWAY | 0.9576720 | 0.9936433 | 0.0606404 | -0.1994182 | -0.5703540 | 16 | PPP2CA;PPP2R5A;PPP2R2A;PPP2R3B;PPP2R5D;PPP2CB;PPP2R2D;PPP2R2B;PPP2R1A;PPP2R5B;PPP2R2C;PPP2R5C;PPP2R3C;PPP2R3A;PPP2R5E;PPP2R1B | non-significant |
| KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY | 0.9501312 | 0.9928884 | 0.0606404 | -0.2338665 | -0.5747137 | 10 | ARAF;MAPK3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.9825073 | 1.0000000 | 0.0640704 | -0.1725226 | -0.6044144 | 39 | PINK1;NDUFA7;NDUFB10;NDUFA2 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLOBAL_GENOME_NER | 0.9497354 | 0.9928884 | 0.0610364 | -0.2079589 | -0.6078309 | 17 | DDB2;CCNH;XPC;CETN2;GTF2H5 | non-significant |
| KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 0.9481481 | 0.9928884 | 0.0578530 | -0.1994523 | -0.6082621 | 19 | PPP2CA;PPP2R5A;PPP2R2A;PPP2R3B;AKT3;PPP2R5D;PPP2CB;PPP2R2D;PPP2R2B;PPP2R1A;AKT2;PPP2R5B;AKT1;PPP2R2C;PPP2R5C;PPP2R3C;PPP2R3A;PPP2R5E;PPP2R1B | non-significant |
| KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 0.9095607 | 0.9808677 | 0.0619763 | -0.2497434 | -0.6092650 | 9 | CREBBP;TLR3;TICAM1;IRF3;TBK1;IFNB1;IKBKE;EP300;TRAF3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF8_TO_RAS_ERK_SIGNALING_PATHWAY | 0.9285714 | 0.9899868 | 0.0621124 | -0.2186239 | -0.6115805 | 15 | ARAF;MAPK3;HRAS;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_OKAZAKI_FRAGMENT_MATURATION | 0.8814433 | 0.9725729 | 0.0633597 | -0.2500605 | -0.6372967 | 11 | RNASEH2C;PCNA | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION | 0.8786408 | 0.9725729 | 0.0606404 | -0.2822121 | -0.6413271 | 7 | GUSB;HGSNAT;IDUA;NAGLU;SGSH;IDS;GNS | non-significant |
| KEGG_MEDICUS_PATHOGEN_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_II | 0.8804878 | 0.9725729 | 0.0607719 | -0.3012371 | -0.6500560 | 6 | SDHC;SDHD;SDHA;SDHB;AS3MT;GSTO1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 0.8556701 | 0.9595286 | 0.0647943 | -0.2618881 | -0.6674402 | 11 | CACNA1A | non-significant |
| KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS | 0.8427835 | 0.9568901 | 0.0655321 | -0.2687526 | -0.6849349 | 11 | GLCE | non-significant |
| KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 0.8463415 | 0.9568901 | 0.0626618 | -0.3189128 | -0.6881994 | 6 | PIK3CA;AKT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME | 0.8155340 | 0.9545496 | 0.0642141 | -0.3067275 | -0.6970384 | 7 | PRKACA;PRKAR1A;PRKAR2B;PRKAR1B;PRKAR2A;PRKACG;PRKACB | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN | 0.8269231 | 0.9568901 | 0.0630790 | -0.2932561 | -0.6995531 | 8 | COLEC11 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY | 0.8422460 | 0.9568901 | 0.0673624 | -0.2528725 | -0.6996000 | 14 | ARAF;MAPK3;KIT;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_MANNOSE_TYPE_O_GLYCAN_BIOSYNTHESIS_POMT_TO_POMK | 0.8199513 | 0.9545496 | 0.0640704 | -0.3481080 | -0.7057442 | 5 | POMGNT2;POMT2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 0.8139535 | 0.9545496 | 0.0673624 | -0.2900380 | -0.7075663 | 9 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.8197115 | 0.9545496 | 0.0635008 | -0.2975654 | -0.7098329 | 8 | PIK3CA;AKT3;AKT2;EGFR;AKT1;PIK3CD;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 0.8197115 | 0.9545496 | 0.0635008 | -0.2975654 | -0.7098329 | 8 | PIK3CA;AKT3;PDGFRA;AKT2;AKT1;PIK3CD;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.8197115 | 0.9545496 | 0.0635008 | -0.2975654 | -0.7098329 | 8 | PIK3CA;AKT3;TGFA;AKT2;EGFR;AKT1;PIK3CD;PIK3CB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.8465608 | 0.9568901 | 0.0665892 | -0.2564610 | -0.7174262 | 15 | ARAF;MAPK3;ATP6V0C;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION | 0.7936893 | 0.9545496 | 0.0655321 | -0.3170766 | -0.7205567 | 7 | C5;C7 | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_PI3K_SIGNALING_PATHWAY | 0.8057743 | 0.9545496 | 0.0686326 | -0.2936648 | -0.7216648 | 10 | PIK3CA;AKT3;GNAI2;AKT2;GNAI1;AKT1;PIK3CD;ADRB2;PIK3CB;GNAI3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 0.7829457 | 0.9545496 | 0.0692836 | -0.2975824 | -0.7259713 | 9 | PIK3CA;AKT3;TGFA;AKT2;EGFR;AKT1;PIK3CD;MTOR;PIK3CB | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.7829457 | 0.9545496 | 0.0692836 | -0.2975824 | -0.7259713 | 9 | PIK3CA;AKT3;AKT2;AKT1;PIK3CD;MET;MTOR;GAB1;PIK3CB | non-significant |
| KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY | 0.7815534 | 0.9545496 | 0.0662842 | -0.3208666 | -0.7291695 | 7 | RIPK3;TRAF5;TNFRSF1A;TNF;RIPK1;TRAF2;TRADD | non-significant |
| KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY | 0.7836538 | 0.9545496 | 0.0656814 | -0.3068805 | -0.7320538 | 8 | PRKCA | non-significant |
| KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY | 0.8632479 | 0.9627936 | 0.0692836 | -0.2214518 | -0.7378455 | 32 | GNG11;PIK3R5;GNG13;GNG4;GNG12;GNG2;LPAR1;AKT3;GNB4;F2R;GNB2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 0.7692308 | 0.9545496 | 0.0665892 | -0.3114301 | -0.7429068 | 8 | PIK3CA;RET;AKT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.8518519 | 0.9590141 | 0.0699459 | -0.2250037 | -0.7453074 | 31 | GNG11;GNG13;GNG4;PIK3CA;GNG12;GNG2;IKBKB | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY | 0.7739362 | 0.9545496 | 0.0713053 | -0.2854537 | -0.7502652 | 12 | PRKCA;ARAF;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS | 0.7731959 | 0.9545496 | 0.0697793 | -0.2978611 | -0.7591198 | 11 | CPT1C;CPT1B;ACSL3;ACSL6 | non-significant |
| KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7680412 | 0.9545496 | 0.0701132 | -0.3007019 | -0.7663598 | 11 | ARAF;MAPK3;HRAS;RET;RAF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE | 0.7365854 | 0.9487678 | 0.0694481 | -0.3565768 | -0.7694766 | 6 | COLEC11 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPG_TO_TNF_NFKB_SIGNALING_PATHWAY | 0.7257282 | 0.9487678 | 0.0699459 | -0.3393509 | -0.7711750 | 7 | SKP1;BTRC;FBXW11;CUL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY | 0.7830688 | 0.9545496 | 0.0704501 | -0.2759194 | -0.7718594 | 15 | FLT3;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAQ_PLCB_G_CALCINEURIN | 0.7724868 | 0.9545496 | 0.0711327 | -0.2645608 | -0.7732692 | 17 | NFATC4;NFATC1;PPP3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 0.7286822 | 0.9487678 | 0.0728939 | -0.3187064 | -0.7775047 | 9 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 0.7500000 | 0.9545496 | 0.0713053 | -0.3054180 | -0.7783792 | 11 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55 | 0.7080292 | 0.9465876 | 0.0713053 | -0.3842368 | -0.7789907 | 5 | MAP1LC3A | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7647059 | 0.9545496 | 0.0721798 | -0.2816224 | -0.7791399 | 14 | FLT3;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119 | 0.7920228 | 0.9545496 | 0.0736213 | -0.2360698 | -0.7819630 | 31 | CBX4;CTBP1;EZH1;SCML1;RING1;PHF1;CBX6;RBBP4;PHC3;BMI1;PHC2;CTBP2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.7458564 | 0.9538948 | 0.0751182 | -0.2436166 | -0.7855441 | 26 | GNG11;GNG13;CFL2;GNG4;GNG12;GNG2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY | 0.7566138 | 0.9545496 | 0.0721798 | -0.2816597 | -0.7879172 | 15 | SRC;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY | 0.7539683 | 0.9545496 | 0.0723571 | -0.2820387 | -0.7889775 | 15 | SRC;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY | 0.6826923 | 0.9390812 | 0.0725352 | -0.3314116 | -0.7905720 | 8 | SMAD3 | non-significant |
| KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.7407407 | 0.9493137 | 0.0732559 | -0.2731327 | -0.7983234 | 17 | NFATC4;NFATC1;PPP3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY | 0.7287234 | 0.9487678 | 0.0743625 | -0.2555217 | -0.8046340 | 23 | GNG11;GNG13;GNG4;GNG12;GNG2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL | 0.7238606 | 0.9487678 | 0.0751182 | -0.2509139 | -0.8056132 | 25 | CACNA1A;CACNA2D2;CACNG6;CACNG1;CACNA1H;CACNA2D4 | non-significant |
| KEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION | 0.7164948 | 0.9487678 | 0.0736213 | -0.3180661 | -0.8106137 | 11 | RPA4 | non-significant |
| KEGG_MEDICUS_VARIANT_EWSR1_WT1_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.6878049 | 0.9419275 | 0.0728939 | -0.3763296 | -0.8121023 | 6 | BAIAP3;TSPAN7 | non-significant |
| KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 0.7071823 | 0.9465876 | 0.0778840 | -0.2518925 | -0.8122297 | 26 | CBX4;MBD5;SCML1;RING1;CBX6;PHC3;BMI1;PHC2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CORE_NER_REACTION | 0.7237569 | 0.9487678 | 0.0766747 | -0.2492588 | -0.8122633 | 28 | RPA4;POLE4;PCNA;ERCC5;XRCC1;GTF2H5 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 0.7036082 | 0.9465876 | 0.0745501 | -0.2608078 | -0.8172806 | 22 | CD86 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.7116402 | 0.9487678 | 0.0753094 | -0.2949804 | -0.8251807 | 15 | PDGFRB;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY | 0.6480583 | 0.9302737 | 0.0756946 | -0.3637535 | -0.8266300 | 7 | SRC | non-significant |
| KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY | 0.6957672 | 0.9424068 | 0.0764767 | -0.2837996 | -0.8295010 | 17 | PDGFRB;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_ATR_SIGNALING | 0.6648936 | 0.9309071 | 0.0791317 | -0.3157625 | -0.8299264 | 12 | RPA4 | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_HOLLIDAY_JUNCTION_RESOLUTION | 0.6520681 | 0.9302737 | 0.0755015 | -0.4103250 | -0.8318811 | 5 | SLX4;SLX1A | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048 | 0.6432039 | 0.9302737 | 0.0760837 | -0.3666482 | -0.8332082 | 7 | TRAP1;PINK1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_TUBA4A_TO_RETROGRADE_AXONAL_TRANSPORT | 0.6796657 | 0.9381657 | 0.0804200 | -0.2594826 | -0.8402301 | 27 | DNALI1;DNAI1;DCTN4;DCTN1 | non-significant |
| KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.6649485 | 0.9309071 | 0.0774768 | -0.3309327 | -0.8434052 | 11 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_I | 0.7065527 | 0.9465876 | 0.0795565 | -0.2348868 | -0.8551566 | 44 | MAPT;NDUFA7;NDUFB10;NDUFA2;CDK5;NDUFAB1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY | 0.6375661 | 0.9302737 | 0.0810802 | -0.3058011 | -0.8554507 | 15 | CCND1;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.6043689 | 0.9176949 | 0.0793435 | -0.3771942 | -0.8571741 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY | 0.6375661 | 0.9302737 | 0.0810802 | -0.3069282 | -0.8586035 | 15 | ARAF;MAPK3;KITLG;KIT;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 0.6382429 | 0.9302737 | 0.0797706 | -0.3523756 | -0.8596427 | 9 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE | 0.6430446 | 0.9302737 | 0.0802023 | -0.3502600 | -0.8607442 | 10 | TFEB;PPP3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR | 0.6407507 | 0.9302737 | 0.0815265 | -0.3215544 | -0.8640862 | 13 | MAP1LC3A;NBR1;WDFY3;OPTN;CALCOCO2;SQSTM1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY | 0.6298343 | 0.9302737 | 0.0840746 | -0.2697530 | -0.8698214 | 26 | GNG11;GNG13;CFL2;GNG4;GNG12;GNG2 | non-significant |
| KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 0.6336898 | 0.9302737 | 0.0819779 | -0.3146157 | -0.8704194 | 14 | BAD;FLT3;PIK3CA;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_STEROID_HORMONE_BIOSYNTHESIS_PROGESTERONE_TO_CORTISOL_CORTISONE | 0.6082725 | 0.9183431 | 0.0791317 | -0.4297528 | -0.8712685 | 5 | HSD11B2;CYP21A2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CREATINE_PATHWAY | 0.6048780 | 0.9176949 | 0.0795565 | -0.4050324 | -0.8740416 | 6 | GAMT | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119 | 0.6390977 | 0.9302737 | 0.0780892 | -0.2839228 | -0.8743892 | 20 | USP7;EZH1;SKP1;RING1;YAF2;RBBP4;PCGF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2 | 0.5985401 | 0.9176949 | 0.0799859 | -0.4331651 | -0.8781865 | 5 | UVRAG | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION | 0.5631068 | 0.8926225 | 0.0831291 | -0.3866027 | -0.8785548 | 7 | HTT | non-significant |
| KEGG_MEDICUS_VARIANT_TMPRSS2_ERG_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.5631068 | 0.8926225 | 0.0831291 | -0.3866602 | -0.8786856 | 7 | PLAT | non-significant |
| KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 0.6115486 | 0.9210427 | 0.0828962 | -0.3586668 | -0.8814036 | 10 | BAD;PIK3CA;HGF;AKT3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM | 0.5984252 | 0.9176949 | 0.0840746 | -0.3602071 | -0.8851886 | 10 | AKR1C3;EPHX4;EPHX2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY | 0.5697115 | 0.8927885 | 0.0819779 | -0.3716300 | -0.8865116 | 8 | PRKCA;PTK2 | non-significant |
| KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_SECOND_CARBON_OXIDATION_2 | 0.5984252 | 0.9176949 | 0.0840746 | -0.3608941 | -0.8868770 | 10 | SDHC;SUCLG1;FH;SUCLA2;MDH1;SDHD;SDHA;SDHB;MDH2;SUCLG2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_P53_MEDIATED_TRANSCRIPTION | 0.5695538 | 0.8927885 | 0.0867950 | -0.3673426 | -0.9027237 | 10 | DDB2;GADD45A | non-significant |
| KEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION | 0.5480769 | 0.8891992 | 0.0840746 | -0.3798112 | -0.9060276 | 8 | HYAL1;HYAL3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY | 0.5661376 | 0.8926225 | 0.0875697 | -0.3244979 | -0.9077532 | 15 | SRC;PRKD3;PRKD1;IKBKB | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.5634921 | 0.8926225 | 0.0878313 | -0.3251503 | -0.9095782 | 15 | CCND1;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 0.5915493 | 0.9176949 | 0.0886261 | -0.2764740 | -0.9113908 | 30 | GNG11;GNG13;GNG4;PIK3CA;GNG12;GNG2;IKBKB | non-significant |
| KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.5441595 | 0.8887461 | 0.0940503 | -0.2828758 | -0.9370042 | 31 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3;PBX1 | non-significant |
| KEGG_MEDICUS_REFERENCE_DOUBLE_STRAND_BREAK_SIGNALING | 0.5360825 | 0.8825400 | 0.0891647 | -0.3682590 | -0.9385338 | 11 | RAD50;UBE2N;MDC1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY | 0.5223097 | 0.8751294 | 0.0916795 | -0.3819285 | -0.9385678 | 10 | CCND1;ARAF;MAPK3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ELECTRON_TRANSFER_IN_COMPLEX_III | 0.5170604 | 0.8697293 | 0.0922597 | -0.3822600 | -0.9393825 | 10 | HTT | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT | 0.5487465 | 0.8891992 | 0.0922597 | -0.2918824 | -0.9451439 | 27 | DNALI1;DNAI1;DCTN4;DCTN1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY | 0.5337079 | 0.8825400 | 0.0943564 | -0.2912723 | -0.9469777 | 29 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY | 0.5120192 | 0.8697293 | 0.0878313 | -0.3975191 | -0.9482693 | 8 | SMAD3 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION | 0.5259259 | 0.8751294 | 0.0878313 | -0.3119567 | -0.9513623 | 19 | WNT3;WNT4 | non-significant |
| KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 0.5167959 | 0.8697293 | 0.0913924 | -0.3912103 | -0.9543827 | 9 | PIK3CA;PAQR5;AKT3;PAQR8 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_TP53_TO_TRANSCRIPTION | 0.5012920 | 0.8643447 | 0.0931455 | -0.3953805 | -0.9645561 | 9 | DDB2;GADD45A | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4973404 | 0.8599266 | 0.0952880 | -0.3676593 | -0.9663280 | 12 | CCND1;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_COHESIN_LOADING | 0.4832041 | 0.8527089 | 0.0952880 | -0.3986529 | -0.9725393 | 9 | NIPBL;RAD21 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.4904110 | 0.8527089 | 0.0978773 | -0.3106747 | -0.9802519 | 24 | GNG11;PIK3R5;GNG13;GNG4;GNG12;GNG2 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY | 0.4629630 | 0.8314343 | 0.0992333 | -0.3517755 | -0.9840599 | 15 | FGFR2;ARAF;MAPK3;HRAS;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY | 0.4444444 | 0.8236860 | 0.1017139 | -0.3475572 | -0.9940452 | 16 | NFATC4;NFATC1;PPP3CA | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 0.4639423 | 0.8314343 | 0.0934449 | -0.4174248 | -0.9957537 | 8 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS | 0.4617284 | 0.8314343 | 0.0952880 | -0.5329788 | -1.0001343 | 4 | SULT1A1;SULT1A4 | non-significant |
| KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.4472934 | 0.8244376 | 0.1059203 | -0.3004014 | -1.0008941 | 32 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3;PBX1;PRKACA;STAR | non-significant |
| KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY | 0.4223301 | 0.8043764 | 0.0995791 | -0.4422471 | -1.0050067 | 7 | IGF1;STAT5A;STAT5B;GHR | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY | 0.4475138 | 0.8244376 | 0.1039585 | -0.3139989 | -1.0124925 | 26 | GNG11;GNG13;GNG4;GNG12;MAPK3;GNG2;CXCR2;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.4302885 | 0.8149959 | 0.0978773 | -0.4303385 | -1.0265589 | 8 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.4160207 | 0.7997416 | 0.1043440 | -0.4218662 | -1.0291695 | 9 | MAP1LC3A;NBR1 | non-significant |
| KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.4122340 | 0.7974582 | 0.1067299 | -0.3948278 | -1.0377358 | 12 | KIF5C | non-significant |
| KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.4122563 | 0.7974582 | 0.1096841 | -0.3215898 | -1.0413394 | 27 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 0.4155496 | 0.7997416 | 0.1067299 | -0.3247950 | -1.0428248 | 25 | GNG11;PIK3R5;GNG13;GNG4;GNG12;GNG2;CXCR2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY | 0.3980583 | 0.7847072 | 0.1031975 | -0.4604833 | -1.0464486 | 7 | BCL2 | non-significant |
| KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION | 0.4041995 | 0.7872529 | 0.1071402 | -0.4269466 | -1.0491973 | 10 | C4B;COLEC11 | non-significant |
| KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY | 0.3968254 | 0.7847072 | 0.1088201 | -0.3771297 | -1.0549860 | 15 | CCND1;PRKCA;ARAF;MAPK3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.3784530 | 0.7812621 | 0.1147507 | -0.3272638 | -1.0552653 | 26 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY | 0.3875969 | 0.7846587 | 0.1088201 | -0.4335395 | -1.0576473 | 9 | BMPR1B | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY | 0.3671875 | 0.7812621 | 0.1128434 | -0.3564465 | -1.0578730 | 18 | BCL2;ARAF;CHRNB2;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN | 0.3731707 | 0.7812621 | 0.1075544 | -0.4904339 | -1.0583341 | 6 | UVRAG | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.3729282 | 0.7812621 | 0.1157344 | -0.3287827 | -1.0601630 | 26 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.3674033 | 0.7812621 | 0.1167392 | -0.3291151 | -1.0612350 | 26 | IGF1R;LMO2;FLT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 0.3840206 | 0.7844596 | 0.1092500 | -0.4166735 | -1.0619215 | 11 | ERBB4;PIK3CA;NRG2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY | 0.3764045 | 0.7812621 | 0.1162341 | -0.3267086 | -1.0621873 | 29 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3;PBX1;PRKACA;STAR | non-significant |
| KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY | 0.3786408 | 0.7812621 | 0.1063233 | -0.4691776 | -1.0662063 | 7 | BMPR1B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY | 0.3643836 | 0.7812621 | 0.1167392 | -0.3381072 | -1.0668081 | 24 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY | 0.3535912 | 0.7812621 | 0.1193484 | -0.3298237 | -1.0748011 | 28 | PREX1;GNG11;PIK3R5;GNG13;GNG4;GNG12;GNG2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3595506 | 0.7812621 | 0.1193484 | -0.3315140 | -1.0778107 | 29 | WNT3;WNT4;GLI1;SMO;GLI3;WNT2B | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 0.3595506 | 0.7812621 | 0.1193484 | -0.3315140 | -1.0778107 | 29 | WNT3;WNT4;GLI1;SMO;GLI3;WNT2B | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_MIR2_TO_CELL_SURFACE_MOLECULE_ENDOCYTOSIS | 0.3634146 | 0.7812621 | 0.1092500 | -0.5010045 | -1.0811451 | 6 | CD86 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAS_AC_PKA_SIGNALING_PATHWAY | 0.3590426 | 0.7812621 | 0.1157344 | -0.3448947 | -1.0860681 | 23 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY | 0.3386243 | 0.7649944 | 0.1193484 | -0.3848626 | -1.1007419 | 16 | ESR1;SRC;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT | 0.3307494 | 0.7561805 | 0.1193484 | -0.4514043 | -1.1012298 | 9 | KIF5C | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_DEGRADATION_BY_EXTRACELLULAR_ENDOLYSOSOMAL_DNASE | 0.3300971 | 0.7561805 | 0.1152400 | -0.4878229 | -1.1085778 | 7 | DNASE1L3;DNASE1L2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_RXRA_LXRA_MEDIATED_TRANSCRIPTION | 0.3414634 | 0.7686031 | 0.1133129 | -0.5143137 | -1.1098657 | 6 | CCND1;PSME3 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 0.3058511 | 0.7309722 | 0.1268757 | -0.4280200 | -1.1249757 | 12 | ESR1;PIK3CA;CCND3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 0.3228346 | 0.7484444 | 0.1221079 | -0.4584383 | -1.1265864 | 10 | CD86;PIK3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 0.3173077 | 0.7435265 | 0.1172497 | -0.4765623 | -1.1368242 | 8 | BAD;PIK3CA | non-significant |
| KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY | 0.2971576 | 0.7194901 | 0.1268757 | -0.4666768 | -1.1384880 | 9 | PTK2;TLN2;VCL;ITGA5 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY | 0.3195122 | 0.7435265 | 0.1177658 | -0.5280757 | -1.1395635 | 6 | HTT;MAP3K10 | non-significant |
| KEGG_MEDICUS_REFERENCE_VALINE_DEGRADATION | 0.3076923 | 0.7325444 | 0.1193484 | -0.4779259 | -1.1400772 | 8 | ACADS;HIBADH;ACADM;HADHA | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 0.2919897 | 0.7149810 | 0.1281429 | -0.4700840 | -1.1468001 | 9 | FGFR2;PIK3CA;FGFR1;AKT3 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_LINKAGE_TETRASACCHARIDE | 0.3187348 | 0.7435265 | 0.1177658 | -0.5657414 | -1.1469681 | 5 | B3GALT6;XYLT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_INTRINSIC_APOPTOTIC_PATHWAY | 0.2975871 | 0.7194901 | 0.1294429 | -0.4276325 | -1.1491411 | 13 | BCL2;PMAIP1;BAD | non-significant |
| KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION | 0.3028846 | 0.7266883 | 0.1204334 | -0.4820081 | -1.1498150 | 8 | EEA1;RABEP1;RAB5C;RAB5B | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_ARSENIC_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2698413 | 0.6894431 | 0.1357409 | -0.3951828 | -1.1550563 | 17 | COX6C;COX4I2;COX7A1 | non-significant |
| KEGG_MEDICUS_VARIANT_AMPLIFIED_REL_TO_TRANSCRIPTION | 0.2812500 | 0.7019909 | 0.1256399 | -0.4907944 | -1.1707746 | 8 | CD86;CCND2 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381 | 0.2712766 | 0.6894431 | 0.1357409 | -0.4501769 | -1.1832112 | 12 | NOTCH4;HEY1;MFNG | non-significant |
| KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 0.2853659 | 0.7065659 | 0.1256399 | -0.5489995 | -1.1847161 | 6 | MAGI2;AKT3;PTEN;AKT2;MAGI1;AKT1 | non-significant |
| KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.2513369 | 0.6678418 | 0.1420566 | -0.4313787 | -1.1934575 | 14 | CCND1;PRKCA;ARAF;MAPK3 | non-significant |
| KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27 | 0.2500000 | 0.6678418 | 0.1395997 | -0.4705051 | -1.1991152 | 11 | PCGF5;PCGF3;RING1;YAF2;FBRS;DCAF7 | non-significant |
| KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.2120344 | 0.6401527 | 0.1619789 | -0.3475978 | -1.1997649 | 37 | WNT3;WNT4;CCND1;LEF1;LRP6;AXIN1;TCF7;WNT2B;DVL3 | non-significant |
| KEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION | 0.2440945 | 0.6676285 | 0.1429011 | -0.4883025 | -1.1999761 | 10 | ACADSB;ACADS;HADH | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382 | 0.2466488 | 0.6678418 | 0.1437590 | -0.4487671 | -1.2059343 | 13 | NOTCH4;HEY1 | non-significant |
| KEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION | 0.1963190 | 0.6168603 | 0.1404062 | -0.9065314 | -1.2126116 | 1 | CCND2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 0.2386059 | 0.6676285 | 0.1464162 | -0.4515200 | -1.2133321 | 13 | GLI1;SMO;GLI3 | non-significant |
| KEGG_MEDICUS_REFERENCE_RENIN_ANGIOTENSIN_SIGNALING_PATHWAY | 0.2554745 | 0.6678418 | 0.1335550 | -0.5999366 | -1.2162945 | 5 | AGT;AGTR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION | 0.2536585 | 0.6678418 | 0.1342735 | -0.5649057 | -1.2190411 | 6 | RBCK1;SHARPIN | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 0.2293814 | 0.6634912 | 0.1464162 | -0.4795007 | -1.2220410 | 11 | AREG | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.2548544 | 0.6678418 | 0.1335550 | -0.5407865 | -1.2289375 | 7 | ESR1;DLL1 | non-significant |
| KEGG_MEDICUS_VARIANT_AREG_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 0.2283465 | 0.6634912 | 0.1482615 | -0.5028394 | -1.2356997 | 10 | AREG | non-significant |
| KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY | 0.2010582 | 0.6235361 | 0.1596467 | -0.4321849 | -1.2360878 | 16 | HEY2;JAG1;NOTCH4;HEYL;HEY1 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 0.2403846 | 0.6676285 | 0.1372508 | -0.5195865 | -1.2394571 | 8 | CDON;LRP2;BOC;GAS1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.2169312 | 0.6401527 | 0.1531588 | -0.4439662 | -1.2419550 | 15 | COX6C;COX4I2;COX7A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION | 0.2192513 | 0.6401725 | 0.1531588 | -0.4490814 | -1.2424338 | 14 | SLX4;FAN1;SLX1A;REV3L | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 0.2331731 | 0.6659295 | 0.1395997 | -0.5219935 | -1.2451990 | 8 | BAD;PIK3CA;KIT;AKT3 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ELECTRON_TRANSFER_IN_COMPLEX_IV | 0.1931217 | 0.6168603 | 0.1631801 | -0.4411156 | -1.2616306 | 16 | COX6C;COX4I2;COX7A1 | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_CAM_CN_SIGNALING_PATHWAY | 0.2021277 | 0.6235361 | 0.1596467 | -0.4823244 | -1.2677053 | 12 | NFATC4;NFATC1;PPP3CA | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY | 0.1978610 | 0.6185653 | 0.1619789 | -0.4597532 | -1.2719586 | 14 | CCND1;PRKCA;ARAF;MAPK3;PLCG1;RAF1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_EBV_EBNA1_TO_P53_MEDIATED_TRANSCRIPTION | 0.1837270 | 0.5985633 | 0.1669338 | -0.5218243 | -1.2823540 | 10 | USP7;DDB2;GADD45A | non-significant |
| KEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS | 0.1452055 | 0.5619099 | 0.1938133 | -0.4086145 | -1.2892751 | 24 | PIGT;PIGP;PIGG;PIGX;PIGB;PIGQ;PIGY;GPAA1;PIGL | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.1829268 | 0.5985633 | 0.1608014 | -0.6032502 | -1.3017868 | 6 | AMBRA1;BECN1;PIK3R4;PIK3C3;ATXN3 | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 0.0900000 | 0.4731730 | 0.2765006 | -0.3075067 | -1.3055278 | 88 | AREG;IGF1R;ERBB4;IGF2;PDGFD;FGF18;FGFR2;IGF1;TEK;PDGFRB;INSR;NGFR;NTRK2;FLT3;PGF;PIK3CA;NTF4;KDR;KITLG;KIT;ANGPT1;HRAS;FGFR3;EFNA1;FGFR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY | 0.1728723 | 0.5895450 | 0.1737478 | -0.4969404 | -1.3061209 | 12 | CCND1;LEF1;AXIN1;TCF7;AXIN2 | non-significant |
| KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2 | 0.1728723 | 0.5895450 | 0.1737478 | -0.4971097 | -1.3065658 | 12 | PCGF5;PCGF3;RING1;YAF2;FBRS;DCAF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE | 0.1899038 | 0.6154475 | 0.1563124 | -0.5482322 | -1.3077906 | 8 | MRAS;ARAF;SHOC2;RAF1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 0.1649485 | 0.5895450 | 0.1752040 | -0.5156258 | -1.3141084 | 11 | IGF1R;IGF2 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEME_BIOSYNTHESIS | 0.1782946 | 0.5895450 | 0.1682382 | -0.5429657 | -1.3245996 | 9 | ALAS2;UROD;ALAD;CPOX;PPOX | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION | 0.1757106 | 0.5895450 | 0.1695706 | -0.5452932 | -1.3302777 | 9 | CLU;CD59;C7 | non-significant |
| KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY | 0.1375661 | 0.5529444 | 0.1957890 | -0.4770600 | -1.3345317 | 15 | AREG;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4 | 0.1470588 | 0.5619099 | 0.1900233 | -0.4838448 | -1.3386107 | 14 | FZD8;FZD10;FZD3;LRP6;FZD2 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_BPA_TO_RAS_ERK_SIGNALING_PATHWAY | 0.1420912 | 0.5602193 | 0.1938133 | -0.4984046 | -1.3393211 | 13 | ESR1;SRC;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 0.0330017 | 0.2622362 | 0.3217759 | -0.3203571 | -1.3439890 | 82 | AREG;IGF1R;ERBB4;IGF2;PDGFD;FGF18;FGFR2;IGF1;TEK;PDGFRB;INSR;NGFR;NTRK2;FLT3;PGF;PIK3CA;NTF4;KDR;KITLG;KIT;ANGPT1;FGFR3;EFNA1;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY | 0.1011561 | 0.4853996 | 0.2413400 | -0.3955031 | -1.3478657 | 35 | SMARCD3;ADCY1;ADCY9;ADCY4;ADCY6;ADCY3;DPF3;PRKACA;KDM3B | non-significant |
| KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY | 0.0333310 | 0.2622362 | 0.3217759 | -0.3187302 | -1.3545088 | 91 | AREG;IGF1R;ERBB4;IGF2;PDGFD;FGF18;FGFR2;IGF1;TEK;PDGFRB;INSR;NGFR;NTRK2;FLT3;PGF;ARAF;NTF4;KDR;MAPK3;KITLG;KIT;ANGPT1;HRAS;FGFR3;EFNA1;FGFR1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.1338583 | 0.5525905 | 0.1978220 | -0.5518905 | -1.3562401 | 10 | MAP1LC3A;PINK1;FAF2;CISD2;FKBP8;SQSTM1 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.1512195 | 0.5682357 | 0.1782199 | -0.6288302 | -1.3569871 | 6 | LEF1;TCF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_MTORC1_PI3KC3_C1 | 0.1058201 | 0.4945019 | 0.2249661 | -0.4987457 | -1.3951955 | 15 | MLST8;TELO2;RPTOR;ULK1;TTI1;AKT1S1;ATG13;BECN1;RB1CC1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TSC1_2_MTORC1_SIGNALING_PATHWAY | 0.1159794 | 0.5075966 | 0.2114002 | -0.5516774 | -1.4059884 | 11 | MLST8;TELO2;TSC2;RPTOR;TTI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION | 0.1159794 | 0.5075966 | 0.2114002 | -0.5534543 | -1.4105170 | 11 | NOTCH4;APH1A | non-significant |
| KEGG_MEDICUS_REFERENCE_BETA_OXIDATION | 0.1134021 | 0.5075966 | 0.2139279 | -0.5569229 | -1.4193570 | 11 | ACADSB;ACADS;HADH;ACAT1 | non-significant |
| KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY | 0.0944882 | 0.4731730 | 0.2377938 | -0.5791823 | -1.4233080 | 10 | ADCY9;ADCY6;ADCY3;PRKACA | non-significant |
| KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY | 0.0899471 | 0.4731730 | 0.2450418 | -0.5098282 | -1.4261978 | 15 | IGF1R;IGF2;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS | 0.0918635 | 0.4731730 | 0.2413400 | -0.5852488 | -1.4382162 | 10 | SHC2;SHC4;GAB2 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY | 0.0820106 | 0.4614959 | 0.2572065 | -0.5054450 | -1.4456184 | 16 | FZD8;FZD10;FZD3;DVL3;FZD2;DVL2;ROR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL | 0.0455475 | 0.3203855 | 0.3217759 | -0.4526316 | -1.4532717 | 25 | IGF1R;ERBB4;FGFR2;TEK;PDGFRB;INSR;NGFR;NTRK2;FLT3;KDR;KIT;FGFR3;FGFR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM | 0.0948905 | 0.4731730 | 0.2279872 | -0.7205382 | -1.4607987 | 5 | DDC;MAOA | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 0.0831099 | 0.4634688 | 0.2572065 | -0.5455854 | -1.4661062 | 13 | IGF1R;IGF1;TSC2;PIK3CA | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 0.0775401 | 0.4500683 | 0.2663507 | -0.5385360 | -1.4899200 | 14 | IGF1R;IGF1;PIK3CA;IKBKB | non-significant |
| KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY | 0.0951220 | 0.4731730 | 0.2279872 | -0.6919213 | -1.4931348 | 6 | PLCD4;PLCD1;PLCD3 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY | 0.0297929 | 0.2581187 | 0.3524879 | -0.4067549 | -1.4959586 | 46 | WNT3;WNT4;FZD8;CCND1;FZD10;LEF1;FZD3;LRP6;AXIN1;TCF7;WNT2B;DVL3;FZD2;AXIN2 | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY | 0.0661376 | 0.4177465 | 0.2878571 | -0.5236681 | -1.4977383 | 16 | PGR;CCND1;SRC;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY | 0.1019417 | 0.4853996 | 0.2192503 | -0.6608308 | -1.5017384 | 7 | CCND1;LEF1;TCF7 | non-significant |
| KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 0.0236338 | 0.2277509 | 0.3524879 | -0.4136161 | -1.5031242 | 45 | WNT3;WNT4;FZD8;CCND1;FZD10;LEF1;FZD3;LRP6;AXIN1;TCF7;WNT2B;DVL3;FZD2;AXIN2 | non-significant |
| KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY | 0.0419853 | 0.2987233 | 0.3217759 | -0.4789604 | -1.5082390 | 23 | GSTM1;GSTM4;GSTM3;GSTT2;GSTM5;KEAP1;GSTA3;GSTA4;GSTA5;GSTA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_ | 0.0328275 | 0.2622362 | 0.3217759 | -0.8637943 | -1.5152311 | 3 | AMY1C | non-significant |
| KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.0721925 | 0.4381095 | 0.2765006 | -0.5512201 | -1.5250122 | 14 | MAP1LC3A;PINK1;NBR1;FAF2;CISD2;OPTN;FKBP8;CALCOCO2;SQSTM1 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION | 0.0780488 | 0.4500683 | 0.2529611 | -0.7080348 | -1.5279071 | 6 | HTT;AMBRA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY | 0.0160217 | 0.1928835 | 0.3524879 | -0.5652853 | -1.5639250 | 14 | RRAGB;MLST8;TELO2;RPTOR;NPRL3;RRAGA;TTI1 | non-significant |
| KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY | 0.0310693 | 0.2622362 | 0.3524879 | -0.5473469 | -1.5654617 | 16 | IGF1R;IGF2;IGF1;ARAF;MAPK3;HRAS | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY | 0.0536089 | 0.3597791 | 0.3217759 | -0.5829095 | -1.5664040 | 13 | JAG1;NOTCH4;HEY1;DLL1 | non-significant |
| KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY | 0.0342355 | 0.2622362 | 0.3217759 | -0.5613204 | -1.5702425 | 15 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_DNA_END_RESECTION_AND_RPA_LOADING | 0.0342355 | 0.2622362 | 0.3217759 | -0.5618300 | -1.5716683 | 15 | RBBP8;RPA4;RAD50 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380 | 0.0348155 | 0.2628147 | 0.3217759 | -0.5983294 | -1.5726040 | 12 | JAG1;NOTCH4;HEY1 | non-significant |
| KEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION | 0.0470746 | 0.3243180 | 0.3217759 | -0.6982710 | -1.5868211 | 7 | IVD;MCCC2;HMGCL;ACADM;AUH | non-significant |
| KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_PAI | 0.0326582 | 0.2622362 | 0.3217759 | -0.7423584 | -1.6019758 | 6 | SERPINA5;PLAT | non-significant |
| KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY | 0.0203832 | 0.2206952 | 0.3524879 | -0.5782457 | -1.6175897 | 15 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY | 0.0112451 | 0.1657314 | 0.3807304 | -0.5875049 | -1.6253981 | 14 | RRAGB;MLST8;TELO2;SLC3A2;RPTOR;RRAGA;TTI1;FLCN;AKT1S1 | non-significant |
| KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY | 0.0260734 | 0.2410547 | 0.3524879 | -0.6815535 | -1.6258245 | 8 | CCND1;LEF1;TCF7 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 0.0343152 | 0.2622362 | 0.3217759 | -0.7170691 | -1.6295398 | 7 | PINK1;FAF2;CISD2;OPTN;FKBP8 | non-significant |
| KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 0.0216586 | 0.2238494 | 0.3524879 | -0.8061650 | -1.6343961 | 5 | SCUBE2;DISP1 | non-significant |
| KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY | 0.0108394 | 0.1637641 | 0.3807304 | -0.6434909 | -1.6399815 | 11 | BCL2;PGR;ESR1 | non-significant |
| KEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.0264810 | 0.2410547 | 0.3524879 | -0.6722975 | -1.6401128 | 9 | VPS18;VPS16;VPS39;VPS11 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_CAMP_SIGNALING_PATHWAY | 0.0108471 | 0.1637641 | 0.3807304 | -0.5930233 | -1.6406652 | 14 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.0190028 | 0.2138683 | 0.3524879 | -0.5737308 | -1.6409220 | 16 | ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION | 0.0239157 | 0.2277509 | 0.3524879 | -0.6885516 | -1.6425181 | 8 | JAG1;DLL1;NEURL1B;MIB1;JAG2 | non-significant |
| KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY | 0.0198301 | 0.2191929 | 0.3524879 | -0.6695191 | -1.6453057 | 10 | CCND1;LEF1;AXIN1;TCF7 | non-significant |
| KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 0.0206790 | 0.2206952 | 0.3524879 | -0.6976694 | -1.6642683 | 8 | PGR;SRC;PIK3CA | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY | 0.0119904 | 0.1726061 | 0.3807304 | -0.5334724 | -1.6717167 | 22 | GSTM1;GSTM4;GSTM3;GSTT2;GSTM5;GSTA3;GSTA4;GSTA5;GSTA1 | non-significant |
| KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS | 0.0148291 | 0.1914478 | 0.3807304 | -0.5661082 | -1.6801135 | 18 | GSTM1;GSTM4;GSTM3;GSTT2;GSTM5;GSTA3;GSTA4;GSTA5;GSTA1 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR | 0.0048102 | 0.0992515 | 0.4070179 | -0.5308334 | -1.7298344 | 28 | SFRP1;WNT3;WNT4;SFRP4;FRZB;SFRP2 | non-significant |
| KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR | 0.0051988 | 0.0996580 | 0.4070179 | -0.6320984 | -1.7487708 | 14 | VPS18;MAP1LC3A;VPS16;VPS39;VPS11;BIRC6 | non-significant |
| KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES | 0.0078789 | 0.1318114 | 0.3807304 | -0.7493919 | -1.7876507 | 8 | VPS18;VPS16;VPS39;VPS11 | non-significant |
| KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY | 0.0051438 | 0.0996580 | 0.4070179 | -0.6288868 | -1.7986732 | 16 | CGA;ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY | 0.0043629 | 0.0964514 | 0.4070179 | -0.6352794 | -1.8568205 | 17 | CX3CR1;ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY | 0.0024133 | 0.0777494 | 0.4317077 | -0.6554193 | -1.8745584 | 16 | CGA;ADCY1;ADCY9;ADCY4;ADCY6;ADCY3 | non-significant |
| KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO | 0.0028552 | 0.0777494 | 0.4317077 | -0.6328870 | -1.8783018 | 18 | FZD8;ZNRF3;FZD10;FZD3;RNF43;LGR4;FZD2;RSPO1 | non-significant |
Over-Representation Analysis analysis (per-treat) (ORA)
ora_hallmark_result_list <- list()
ora_keggmed_result_list <- list()
for (treatment in names(top_table_list)) {
message("Running ORA for: ", treatment)
# Extract top table and DE genes
top_full <- top_table_list[[treatment]]
deGenes <- rownames(top_full)[top_full$pval < 0.05]
# Gene universe is all genes in expr_data (assumes same for all treatments)
geneUniverse <- rownames(expr_data)
# # Skip if not enough DE genes
# if (length(deGenes) < 10) {
# message("Skipping ORA for ", treatment, ": too few DE genes")
# next
# }
# ORA Hallmark
oraHallmark <- fora(
pathways = pathwaysH,
genes = deGenes,
universe = geneUniverse,
minSize = 15, maxSize = 500
)
oraHallmark$Pathway_Set <- "Hallmark"
oraHallmark$Significance <- ifelse(oraHallmark$pval < 0.05, "Significant", "Not Significant")
oraHallmark$Treatment <- treatment
ora_hallmark_result_list[[treatment]] <- oraHallmark
# ORA KEGG_MEDICUS
oraKeggMed <- fora(
pathways = pathwaysKEGG_MED,
genes = deGenes,
universe = geneUniverse,
minSize = 15, maxSize = 500
)
oraKeggMed$Pathway_Set <- "KEGG_MEDICUS"
oraKeggMed$Significance <- ifelse(oraKeggMed$pval < 0.05, "Significant", "Not Significant")
oraKeggMed$Treatment <- treatment
ora_keggmed_result_list[[treatment]] <- oraKeggMed
# Save to .tsv files
write.table(
transform(oraHallmark, overlapGenes = sapply(overlapGenes, paste, collapse = ",")),
file = file.path(output_dir, "pathway_analysis", paste0(gsub("\\+", "_", treatment), "_Hallmark_ORA.tsv")),
sep = "\t", row.names = FALSE, quote = FALSE
)
write.table(
transform(oraKeggMed, overlapGenes = sapply(overlapGenes, paste, collapse = ",")),
file = file.path(output_dir, "pathway_analysis", paste0(gsub("\\+", "_", treatment), "_KeggMed_ORA.tsv")),
sep = "\t", row.names = FALSE, quote = FALSE
)
# Optional: Print top hits
print(kable(head(oraHallmark, 10), caption = paste("Top Hallmark ORA -", treatment)) %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed"), full_width = FALSE))
}| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance | Treatment |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_ADIPOGENESIS | 1 | 1 | 0 | 192 | Hallmark | Not Significant | chemo | |
| HALLMARK_ALLOGRAFT_REJECTION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | chemo | |
| HALLMARK_ANDROGEN_RESPONSE | 1 | 1 | 0 | 96 | Hallmark | Not Significant | chemo | |
| HALLMARK_ANGIOGENESIS | 1 | 1 | 0 | 36 | Hallmark | Not Significant | chemo | |
| HALLMARK_APICAL_JUNCTION | 1 | 1 | 0 | 190 | Hallmark | Not Significant | chemo | |
| HALLMARK_APICAL_SURFACE | 1 | 1 | 0 | 43 | Hallmark | Not Significant | chemo | |
| HALLMARK_APOPTOSIS | 1 | 1 | 0 | 159 | Hallmark | Not Significant | chemo | |
| HALLMARK_BILE_ACID_METABOLISM | 1 | 1 | 0 | 112 | Hallmark | Not Significant | chemo | |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 1 | 1 | 0 | 72 | Hallmark | Not Significant | chemo | |
| HALLMARK_COAGULATION | 1 | 1 | 0 | 137 | Hallmark | Not Significant | chemo |
| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance | Treatment |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_ADIPOGENESIS | 1 | 1 | 0 | 192 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_ALLOGRAFT_REJECTION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_ANDROGEN_RESPONSE | 1 | 1 | 0 | 96 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_ANGIOGENESIS | 1 | 1 | 0 | 36 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_APICAL_JUNCTION | 1 | 1 | 0 | 190 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_APICAL_SURFACE | 1 | 1 | 0 | 43 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_APOPTOSIS | 1 | 1 | 0 | 159 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_BILE_ACID_METABOLISM | 1 | 1 | 0 | 112 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 1 | 1 | 0 | 72 | Hallmark | Not Significant | chemo+targeted | |
| HALLMARK_COAGULATION | 1 | 1 | 0 | 137 | Hallmark | Not Significant | chemo+targeted |
| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance | Treatment |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_ADIPOGENESIS | 1 | 1 | 0 | 192 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_ALLOGRAFT_REJECTION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_ANDROGEN_RESPONSE | 1 | 1 | 0 | 96 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_ANGIOGENESIS | 1 | 1 | 0 | 36 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_APICAL_JUNCTION | 1 | 1 | 0 | 190 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_APICAL_SURFACE | 1 | 1 | 0 | 43 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_APOPTOSIS | 1 | 1 | 0 | 159 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_BILE_ACID_METABOLISM | 1 | 1 | 0 | 112 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 1 | 1 | 0 | 72 | Hallmark | Not Significant | IO+chemo | |
| HALLMARK_COAGULATION | 1 | 1 | 0 | 137 | Hallmark | Not Significant | IO+chemo |
| pathway | pval | padj | overlap | size | overlapGenes | Pathway_Set | Significance | Treatment |
|---|---|---|---|---|---|---|---|---|
| HALLMARK_ADIPOGENESIS | 1 | 1 | 0 | 192 | Hallmark | Not Significant | targeted | |
| HALLMARK_ALLOGRAFT_REJECTION | 1 | 1 | 0 | 195 | Hallmark | Not Significant | targeted | |
| HALLMARK_ANDROGEN_RESPONSE | 1 | 1 | 0 | 96 | Hallmark | Not Significant | targeted | |
| HALLMARK_ANGIOGENESIS | 1 | 1 | 0 | 36 | Hallmark | Not Significant | targeted | |
| HALLMARK_APICAL_JUNCTION | 1 | 1 | 0 | 190 | Hallmark | Not Significant | targeted | |
| HALLMARK_APICAL_SURFACE | 1 | 1 | 0 | 43 | Hallmark | Not Significant | targeted | |
| HALLMARK_APOPTOSIS | 1 | 1 | 0 | 159 | Hallmark | Not Significant | targeted | |
| HALLMARK_BILE_ACID_METABOLISM | 1 | 1 | 0 | 112 | Hallmark | Not Significant | targeted | |
| HALLMARK_CHOLESTEROL_HOMEOSTASIS | 1 | 1 | 0 | 72 | Hallmark | Not Significant | targeted | |
| HALLMARK_COAGULATION | 1 | 1 | 0 | 137 | Hallmark | Not Significant | targeted |
8. Gene–Response Correlation
- Tool:
PredictioRR package - Goal: identify individual gene-level associations with response status (R vs NR)
9. Stratified Signature Analysis
- Repeated signature-based analysis (Step 3) within subgroups
- Netx step: Grouped patients by treatment arms to detect treatment-specific associations